Purpose. We aimed to investigate whether the anterior superior iliac spine could provide consistent rotational landmark of the tibial component during mobile-bearing medial unicompartmental knee arthroplasty (UKA) using computed tomography (CT). Methods. During sagittal tibial resection, we utilized the ASIS as a rotational landmark. In 47 knees that underwent postoperative CT scans after medial UKA, the tibial component position was assessed by drawing a line tangential to the lateral wall of the tibial component. Rotation of the tibial component was measured using two reference lines: a line perpendicular to the posterior cortical rim of the tibia (angle α) and Akagi's line (angle β). Instant bearing position and posterior cruciate ligament fossa involvement were also evaluated. External rotation of the tibial component relative to each reference line and external rotation of the bearing relative to the lateral wall of the tibial component were considered positive values. Results. The mean angle α and β were 8.0 ± 6.1° (range, −4.0 – 24.3) and 8.7 ± 4.8° (range, 1.9 – 25.2), respectively. The mean instant bearing position was 4.3 ± 28.6° (range, −52.9 – 179.7). One bearing showed complete 180° rotation at 2 weeks postoperatively. Fourteen knees (29.8%) showed posterior cruciate ligament fossa involvement of the tibial resection margin. Conclusions. Due to the wide variation in, and inherent difficulty in identification of, the ASIS during the operation, it is not recommended for guidance of sagittal tibial resection during mobile-bearing medial UKA. Level of Evidence: Level IV

Aims. The main objective of this study is to analyze the penetration of bone cement in four different full cementation techniques of the tibial tray. Methods. In order to determine the best tibial tray cementation technique, we applied cement to 40 cryopreserved donor tibiae by four different techniques: 1) double-layer cementation of the tibial component and tibial bone with bone restrictor; 2) metallic cementation of the tibial component without bone restrictor; 3) bone cementation of the tibia with bone restrictor; and 4) superficial bone cementation of the tibia and metallic keel cementation of the tibial component without bone restrictor. We performed CT exams of all 40 subjects, and measured cement layer thickness at both levels of the resected surface of the epiphysis and the endomedular metaphyseal level. Results. At the epiphyseal level, Technique 2 gave the greatest depth compared to the other investigated techniques. At the endomedular metaphyseal level, Technique 1 showed greater cement penetration than the other techniques. Conclusion. The best metaphyseal cementation technique of the tibial component is bone cementation with cement restrictor. Additionally, if full tibial component cementation is to be done, the cement volume used should be about 40 g of cement, and not the usual 20 g. Cite this article: Bone Joint Res 2021;10(8):467–473

Aims. Thresholds of acceptable early migration of the components in total knee arthroplasty (TKA) have traditionally ignored the effects of patient and implant factors that may influence migration. The aim of this study was to determine which of these factors are associated with overall longitudinal migration of well-fixed tibial components following TKA. Methods. Radiostereometric analysis (RSA) data over a two-year period were available for 419 successful primary TKAs (267 cemented and 152 uncemented in 257 female and 162 male patients). Longitudinal analysis of data using marginal models was performed to examine the associations of patient factors (age, sex, BMI, smoking status) and implant factors (cemented or uncemented, the size of the implant) with maximum total point motion (MTPM) migration. Analyses were also performed on subgroups based on sex and fixation. Results. In the overall group, only fixation was significantly associated with migration (p < 0.001). For uncemented tibial components in males, smoking was significantly associated with lower migration (p = 0.030) and BMI approached significance (p = 0.061). For females with uncemented components, smoking (p = 0.081) and age (p = 0.063) approached significance and were both associated with increased migration. The small number of self-reported smokers in this study warrants cautious interpretation and further investigation. For cemented components in females, larger sizes of tibial component were significantly associated with increased migration (p = 0.004). No factors were significant for cemented components in males. Conclusion. The migration of uncemented tibial components was more sensitive to patient factors than cemented implants. These differences were not consistent by sex, suggesting that it may be of value to evaluate female and male patients separately following TKA. Cite this article: Bone Joint J 2022;104-B(4):444–451

Aims. Stemmed tibial components are frequently used in revision total knee arthroplasty (TKA). The purpose of this study was to evaluate patient satisfaction, overall pain, and diaphyseal tibial pain in patients who underwent revision TKA with cemented or uncemented stemmed tibial components. Methods. This is a retrospective cohort study involving 110 patients with revision TKA with cemented versus uncemented stemmed tibial components. Patients who underwent revision TKA with stemmed tibial components over a 15-year period at a single institution with at least two-year follow-up were assessed. Pain was evaluated through postal surveys. There were 63 patients with cemented tibial stems and 47 with uncemented stems. Radiographs and Knee Society Scores were used to evaluate for objective findings associated with pain or patient dissatisfaction. Postal surveys were analyzed using Fisher’s exact test and the independent-samples t-test. Logistic regression was used to adjust for age, sex, and preoperative bone loss. Results. No statistically significant differences in stem length, operative side, or indications for revision were found between the two cohorts. Tibial pain at the end of the stem was present in 25.3% (16/63) of cemented stems and 25.5% (12/47) of uncemented stems (p = 1.000); 74.6% (47/63) of cemented patients and 78.7% (37/47) of uncemented patients were satisfied following revision TKA (p = 0.657). Conclusion. There were no differences in patient satisfaction, overall pain, and diaphyseal tibial pain in cemented and uncemented stemmed tibial components in revision TKA. Patient factors, rather than implant selection and surgical technique, likely play a large role in the presence of postoperative pain. Stemmed tibial components have been shown to be a possible source of pain in revision TKA. There is no difference in patient satisfaction or postoperative pain with cemented or uncemented stemmed tibial components in revision TKA. Cite this article: Bone Joint J 2021;103-B(6 Supple A):165–170

Aims. A fracture of the medial tibial plateau is a serious complication of Oxford mobile-bearing unicompartmental knee arthroplasty (OUKA). The risk of these fractures is reportedly lower when using components with a longer keel-cortex distance (KCDs). The aim of this study was to examine how slight varus placement of the tibial component might affect the KCDs, and the rate of tibial plateau fracture, in a clinical setting. Methods. This retrospective study included 255 patients who underwent 305 OUKAs with cementless tibial components. There were 52 males and 203 females. Their mean age was 73.1 years (47 to 91), and the mean follow-up was 1.9 years (1.0 to 2.0). In 217 knees in 187 patients in the conventional group, tibial cuts were made orthogonally to the tibial axis. The varus group included 88 knees in 68 patients, and tibial cuts were made slightly varus using a new osteotomy guide. Anterior and posterior KCDs and the origins of fracture lines were assessed using 3D CT scans one week postoperatively. The KCDs and rate of fracture were compared between the two groups. Results. Medial tibial fractures occurred after surgery in 15 patients (15 OUKAs) in the conventional group, but only one patient (one OUKA) had a tibial fracture after surgery in the varus group. This difference was significant (6.9% vs 1.1%; p = 0.029). The mean posterior KCD was significantly shorter in the conventional group (5.0 mm (SD 1.7)) than in the varus group (6.1 mm (SD 2.1); p = 0.002). Conclusion. In OUKA, the distance between the keel and posterior tibial cortex was longer in our patients with slight varus alignment of the tibial component, which seems to decrease the risk of postoperative tibial fracture. Cite this article: Bone Joint J 2022;104-B(10):1118–1125

We studied the effect of a metal tray with an intramedullary stem on the micromotion of the tibial component in total knee arthroplasty. Of 32 uncemented Freeman-Samuelson knee arthroplasties performed in London and Gothenburg, nine had a metal backing and stem added to the tibial component. Micromotion of the tibial components, expressed as migration and inducible displacement, was analysed using roentgen stereophotogrammetric analysis up to two years follow-up. The addition of a metal back and a 110 mm stem to the standard polyethylene component significantly reduced both migration over two years and inducible displacement

Aims. We aimed to examine the long-term mechanical survivorship, describe the modes of all-cause failure, and identify risk factors for mechanical failure of all-polyethylene tibial components in endoprosthetic reconstruction. Methods. This is a retrospective database review of consecutive endoprosthetic reconstructions performed for oncological indications between 1980 and 2019. Patients with all-polyethylene tibial components were isolated and analyzed for revision for mechanical failure. Outcomes included survival of the all-polyethylene tibial component, revision surgery categorized according to the Henderson Failure Mode Classification, and complications and functional outcome, as assessed by the Musculoskeletal Tumor Society (MSTS) score at the final follow-up. Results. A total of 278 patients were identified with 289 all-polyethylene tibial components. Mechanical survival was 98.4%, 91.1%, and 85.2% at five, ten and 15 years, respectively. A total of 15 mechanical failures were identified at the final follow-up. Of the 13 all-polyethylene tibial components used for revision of a previous tibial component, five (38.5%) failed mechanically. Younger patients (< 18 years vs > 18 years; p = 0.005) and those used as revision components (p < 0.001) had significantly increased rates of failure. Multivariate logistic regression modelling showed revision status to be a positive risk factor for failure (odds ratio (OR) 19.498, 95% confidence interval (CI) 4.598 to 82.676) and increasing age was a negative risk factor for failure (OR 0.927, 95% CI 0.872 to 0.987). Age-stratified risk analysis showed that age > 24 years was no longer a statistically significant risk factor for failure. The final mean MSTS score for all patients was 89% (8.5% to 100.0%). Conclusion. The long-term mechanical survivorship of all-polyethylene tibial components when used for tumour endoprostheses was excellent. Tumour surgeons should consider using these components for their durability and the secondary benefits of reduced cost and ease of removal and revision. However, caution should be taken when using all-polyethylene tibial components in the revision setting as a significantly higher rate of mechanical failure was seen in this group of patients. Cite this article: Bone Joint J. 2020;102-B(2):170–176

Aims. This study aimed to identify the effect of anatomical tibial component (ATC) design on load distribution in the periprosthetic tibial bone of Koreans using finite element analysis (FEA). Methods. 3D finite element models of 30 tibiae in Korean women were created. A symmetric tibial component (STC, NexGen LPS-Flex) and an ATC (Persona) were used in surgical simulation. We compared the FEA measurements (von Mises stress and principal strains) around the stem tip and in the medial half of the proximal tibial bone, as well as the distance from the distal stem tip to the shortest anteromedial cortical bone. Correlations between this distance and FEA measurements were then analyzed. Results. The distance from the distal stem tip to the shortest cortical bone showed no statistically significant difference between implants. However, the peak von Mises stress around the distal stem tip was higher with STC than with ATC. In the medial half of the proximal tibial bone: 1) the mean von Mises stress, maximum principal strain, and minimum principal strain were higher with ATC; 2) ATC showed a positive correlation between the distance and mean von Mises stress; 3) ATC showed a negative correlation between the distance and mean minimum principal strain; and 4) STC showed no correlation between the distance and mean measurements. Conclusion. Implant design affects the load distribution on the periprosthetic tibial bone, and ATC can be more advantageous in preventing stress-shielding than STC. However, under certain circumstances with short distances, the advantage of ATC may be offset. Cite this article: Bone Joint Res 2022;11(5):252–259

Aims. The objective of this study was to compare the two-year migration pattern and clinical outcomes of a total knee arthroplasty (TKA) with an asymmetrical tibial design (Persona PS) and a well-proven TKA with a symmetrical tibial design (NexGen LPS). Methods. A randomized controlled radiostereometric analysis (RSA) trial was conducted including 75 cemented posterior-stabilized TKAs. Implant migration was measured with RSA. Maximum total point motion (MTPM), translations, rotations, clinical outcomes, and patient-reported outcome measures (PROMs) were assessed at one week postoperatively and at three, six, 12, and 24 months postoperatively. Results. A linear mixed-effect model using RSA data of 31 asymmetrical and 38 symmetrical TKAs did not show a difference in mean MTPM migration pattern of the tibial or femoral components. Mean tibial component MTPM at two years postoperative of the asymmetrical TKA design was 0.93 mm and 1.00 mm for the symmetrical design. For the femoral component these values were 1.04 mm and 1.14 mm, respectively. No significant differences were observed in other migration parameters or in clinical and PROM measurements. Conclusion. The TKA design with an asymmetrical tibial component has comparable component migration with the proven TKA with a symmetrical tibial component. This suggests the risk of long-term aseptic loosening of the two designs is comparable. Cite this article: Bone Joint J 2021;103-B(5):855–863

Objectives. Unicompartmental knee arthroplasty (UKA) is one surgical option for treating symptomatic medial osteoarthritis. Clinical studies have shown the functional benefits of UKA; however, the optimal alignment of the tibial component is still debated. The purpose of this study was to evaluate the effects of tibial coronal and sagittal plane alignment in UKA on knee kinematics and cruciate ligament tension, using a musculoskeletal computer simulation. Methods. The tibial component was first aligned perpendicular to the mechanical axis of the tibia, with a 7° posterior slope (basic model). Subsequently, coronal and sagittal plane alignments were changed in a simulation programme. Kinematics and cruciate ligament tensions were simulated during weight-bearing deep knee bend and gait motions. Translation was defined as the distance between the most medial and the most lateral femoral positions throughout the cycle. Results. The femur was positioned more medially relative to the tibia, with increasing varus alignment of the tibial component. Medial/lateral (ML) translation was smallest in the 2° varus model. A greater posterior slope posteriorized the medial condyle and increased anterior cruciate ligament (ACL) tension. ML translation was increased in the > 7° posterior slope model and the 0° model. Conclusion. The current study suggests that the preferred tibial component alignment is between neutral and 2° varus in the coronal plane, and between 3° and 7° posterior slope in the sagittal plane. Varus > 4° or valgus alignment and excessive posterior slope caused excessive ML translation, which could be related to feelings of instability and could potentially have negative effects on clinical outcomes and implant durability. Cite this article: K. Sekiguchi, S. Nakamura, S. Kuriyama, K. Nishitani, H. Ito, Y. Tanaka, M. Watanabe, S. Matsuda. Bone Joint Res 2019;8:126–135. DOI: 10.1302/2046-3758.83.BJR-2018-0208.R2

Objectives. The primary stability of the cementless Oxford Unicompartmental Knee Replacement (OUKR) relies on interference fit (or press fit). Insufficient interference may cause implant loosening, whilst excessive interference could cause bone damage and fracture. The aim of this study was to identify the optimal interference fit by measuring the force required to seat the tibial component of the cementless OUKR (push-in force) and the force required to remove the component (pull-out force). Materials and Methods. Six cementless OUKR tibial components were implanted in 12 new slots prepared on blocks of solid polyurethane foam (20 pounds per cubic foot (PCF), Sawbones, Malmo, Sweden) with a range of interference of 0.1 mm to 1.9 mm using a Dartec materials testing machine HC10 (Zwick Ltd, Herefordshire, United Kingdom) . The experiment was repeated with cellular polyurethane foam (15 PCF), which is a more porous analogue for trabecular bone. Results. The push-in force progressively increased with increasing interference. The pull-out force was related in a non-linear fashion to interference, decreasing with higher interference. Compared with the current nominal interference, a lower interference would reduce the push-in forces by up to 45% (p < 0.001 One way ANOVA) ensuring comparable (or improved) pull-out forces (p > 0.05 Bonferroni post hoc test). With the more porous bone analogue, although the forces were lower, the relationship between interference and push-in and pull-out force were similar. Conclusions. This study suggests that decreasing the interference fit of the tibial component of the cementless OUKR reduces the push-in force and can increase the pull-out force. An optimal interference fit may both improve primary fixation and decrease the risk of fracture. Cite this article: S. Campi, S. J. Mellon, D. Ridley, B. Foulke, C. A. F. Dodd, H. G. Pandit, D. W. Murray. Optimal interference of the tibial component of the cementless Oxford Unicompartmental Knee Replacement. Bone Joint Res 2018;7:226–231. DOI: 10.1302/2046-3758.73.BJR-2017-0193.R1

Aims. A novel enhanced cement fixation (EF) tibial implant with deeper cement pockets and a more roughened bonding surface was released to market for an existing total knee arthroplasty (TKA) system.This randomized controlled trial assessed fixation of the both the EF (ATTUNE S+) and standard (Std; ATTUNE S) using radiostereometric analysis. Methods. Overall, 50 subjects were randomized (21 EF-TKA and 23 Std-TKA in the final analysis), and had follow-up visits at six weeks, and six, 12, and 24 months to assess migration of the tibial component. Low viscosity bone cement with tobramycin was used in a standardized fashion for all subjects. Patient-reported outcome measure data was captured at preoperative and all postoperative visits. Results. The patient cohort mean age was 66 years (SD seven years), 59% were female, and the mean BMI was 32 kg/m. 2. (SD 6 kg/m. 2. ). Mean two-year subsidence of the EF-TKA was 0.056 mm (95% confidence interval (CI) 0.025 to 0.086) versus 0.006 mm (95% CI -0.029 to 0.040) for the Std-TKA, and the two-year maximum total point motion (MTPM) was 0.285 mm (95% upper confidence limit (UCL) ≤ 0.363) versus 0.346 mm (95% UCL ≤ 0.432), respectively, for a mean difference of -0.061 mm (95% CI -0.196 to 0.074). Inducible displacement also did not differ between groups. The MTPMs between 12 and 24 months for each group was below the published threshold of 0.2 mm for predicting early aseptic loosening (p < 0.001 and p = 0.001, respectively). Conclusion. Both the enhanced fixation and the standard tibial implant design showed fixation with a predicted low risk of long-term aseptic loosening. Cite this article: Bone Jt Open 2024;5(1):20–27

Aims. The introduction of a novel design of total knee arthroplasty (TKA) must achieve outcomes at least as good as existing designs. A novel design of TKA with a reducing radius of the femoral component and a modified cam-post articulation has been released and requires assessment of the fixation to bone. Radiostereometric analysis (RSA) of the components within the first two postoperative years has been shown to be predictive of medium- to long-term fixation. The aim of this study was to assess the stability of the tibial component of this system during this period of time using RSA. Patients and Methods. A cohort of 30 patients underwent primary, cemented TKA using the novel posterior stabilized fixed-bearing (ATTUNE) design. There was an even distribution of men and women (15:15). The mean age of the patients was 64 years (sd 8) at the time of surgery; their mean body mass index (BMI) was 35.4 kg/m2 (sd 7.9). RSA was used to assess the stability of the tibial component at 6, 12, and 24 months compared with a six-week baseline examination. Patient-reported outcome measures were also assessed. Results. The mean maximum total point motion (MTPM) of the tibial component between 12 and 24 months postoperatively was 0.08 mm (sd 0.08), which is well below the published threshold of 0.2 mm (p < 0.001). Patient-reported outcome measures consistently improved. Conclusion. The tibial component of this novel design of TKA showed stability between assessment 12 and 24 months postoperatively, suggesting an acceptably low risk of medium- to long-term failure due to aseptic loosening

Objectives. Malalignment of the tibial component could influence the long-term survival of a total knee arthroplasty (TKA). The object of this study was to investigate the biomechanical effect of varus and valgus malalignment on the tibial component under stance-phase gait cycle loading conditions. Methods. Validated finite element models for varus and valgus malalignment by 3° and 5° were developed to evaluate the effect of malalignment on the tibial component in TKA. Maximum contact stress and contact area on a polyethylene insert, maximum contact stress on patellar button and the collateral ligament force were investigated. Results. There was greater total contact stress in the varus alignment than in the valgus, with more marked difference on the medial side. An increase in ligament force was clearly demonstrated, especially in the valgus alignment and force exerted on the medial collateral ligament also increased. Conclusion. These results highlight the importance of accurate surgical reconstruction of the coronal tibial alignment of the knee joint. Varus and valgus alignments will influence wear and ligament stability, respectively in TKA. Cite this article: D-S. Suh, K-T. Kang, J. Son, O-R. Kwon, C. Baek, Y-G. Koh. Computational study on the effect of malalignment of the tibial component on the biomechanics of total knee arthroplasty: A Finite Element Analysis. Bone Joint Res 2017;6:623–630. DOI: 10.1302/2046-3758.611.BJR-2016-0088.R2

Aims. Hydroxyapatite coatings for uncemented fixation in total knee arthroplasty can theoretically provide a long-lasting biological interface with the host bone. The objective of this study was to test this hypothesis with propriety hydroxyapatite, peri-apatite, coated tibial components using component migration measured with radiostereometric analysis over two years as an indicator of long-term fixation. Patients and Methods. A total of 29 patients at two centres received uncemented PA-coated tibial components and were followed for two years with radiostereometric analysis exams to quantify the migration of the component. Results. While there was significant variation in individual migration patterns, the overall migration of the tibial component in the study group demonstrated a pattern of initial migration followed by stabilisation after one year, with mean maximum total point motion (MTPM) of 0.02 mm (standard deviation (. sd. ) 0.20) between one and two years post-operatively. The direction of greatest motion was subsidence, which stabilised at three months post-operatively (mean translation of 0.21 mm, . sd. 0.40). Conclusion. The tibial component migration pattern of stabilisation in the second post-operative year is indicative of successful long-term fixation for this PA-coated tibial component. Cite this article: Bone Joint J 2017;99-B:1596–1602

Abstract. Introduction. Long term survivorship in Total Knee Arthroplasty is significantly dependent on prosthesis alignment. The aim of this study was to determine, compare and analyse the coronal alignment of the tibial component of a single implant system using 3 different techniques. Method. Retrospective study of cases from a prospectively collected database. Radiological assessment included measurement of the coronal alignment of tibial components of total knee arthroplasties, and its deviation from the mechanical axis. A comparison study of intramedullary, extramedullary and tibial crest alignment methods was performed. Results. 66 consecutive patients (3 groups of 22 each). Mean BMI was 26. The mean angle of deviation from the mechanical axis was significantly lesser (p< 0.05) in the Tibial crest alignment group patients compared to the other 2 groups. Moreover, the number of outliers (+/-3 degrees) were 2 and 4 in the intra and extramedullary group, whereas there were none in the tibial crest group. The inter and intraclass correlation coefficient was 0.8 and 0.9 respectively. Conclusion. The Tibial Crest Alignment Technique is an effective technique to produce consistent results to achieve optimal coronal alignment of the tibial component in TKA, even in patients with high BMI. Declaration of Interest. (b) declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research reported:I declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research project

Abstract. Introduction. Cementless fixation of Oxford Unicompartmental Knee Replacements (UKRs) is an alternative to cemented fixation, however, it is unknown whether cementless fixation is as good long-term. This study aimed to compare primary and long-term fixation of cemented and cementless Oxford UKRs using radiostereometric analysis (RSA). Methodology. Twenty-nine patients were randomised to receive cemented or cementless Oxford UKRs and followed for ten years. Differences in primary fixation and long-term fixation of the tibial components (inferred from 0/3/6-month and 6-month/1-year/2-year/5-year/10-year migration, respectively) were analysed using RSA and radiolucencies were assessed on radiographs. Migration rates were determined by linear regression and clinical outcomes measured using the Oxford Knee Score (OKS). Results. Preliminary analysis of Maximum Total Point Motion (MTPM) indicated cementless tibial components undergo significantly more migration than cemented components during the first 6 months (1.6mm/year, SD=0.92 versus 1.3mm/year, SD=1.1, p<0.001). Cementless migration was predominantly subsidence inferiorly (Mean=0.51mm/year, SD=0.29, p<0.001) and posteriorly (0.13mm/year, SD=0.21, p=0.03). Contrastingly, from 6 months to 10 years cemented components migrated significantly (MTPM=0.039mm/year, SD=0.11, p=0.04) whereas cementless components did not (MTPM=0.002mm/year, SD=0.02, p=0.744). Radiolucent lines occurred more frequently below cemented (10/13) than cementless (4/16) tibial components, but radiolucencies did not correlate with differences in migration or OKS. There was no significant difference in OKS between cemented and cementless. Conclusion. These results suggest that cementless tibial components migrate more than cemented before achieving primary fixation. However, long-term fixation of cementless tibial components appears to be as good, if not better, than cemented with the benefit of fewer radiolucent lines

Abstract. Introduction. In cementless UKR, primary fixation of the tibial component is achieved by press-fitting a keel (i.e. with interference) into a vertical slot cut into the proximal tibia. This may adversely affect the structural integrity of surrounding bone. Early post-operative peri-prosthetic tibial fractures are 7x more common in very small knees, but the aetiology of these fractures is unknown - such sizes are rarely used in the UK but more common in Asian populations. This study explores the effect of keel-related features in fracture risk of these very small tibias. Method. This in vitro study compares the effect of keel and slot depth (standard vs 33% shallower vs nil) and loading position (anterior/posterior gait range limits: mid-tibia vs 8mm posterior) on fracture load and path. 3D-printed titanium components were implanted using surgical instrumentation/technique, in bone-analogue foam machined to a CT-reconstructed very small tibia which subsequently experienced a peri-prosthetic fracture. Results. Introducing a standard slot reduces load-to-fracture by 50% (1421N-vs-710N, p<0.0001). Press-fitting a standard keel further reduces load-to-fracture by 40% (710N-vs-423N, p=0.0001). A shallower slot/keel increases load-to-fracture substantially (slot: 27% increase, 904N-vs-710N p=0.0003, slot+keel: 60% increase, 683N-vs-423N p=0.0004). Deeper keels fractured more vertically (current 8.2° vs shallow 15.5° vs nil 21°, degrees-to-vertical, p<0.0001). There was no difference caused by loading position. Conclusion. In very small tibias, a standard cementless keel significantly weakens the bone and may contribute to fractures. Therefore, decreasing interference or using a shallower keel should decrease the risk of fracture, although it might compromise fixation

Aims. The Vantage Total Ankle System is a fourth-generation low-profile fixed-bearing implant that has been available since 2016. We aimed to describe our early experience with this implant. Methods. This is a single-centre retrospective review of patients who underwent primary total ankle arthroplasty (TAA) with a Vantage implant between November 2017 and February 2020, with a minimum of two years’ follow-up. Four surgeons contributed patients. The primary outcome was reoperation and revision rate of the Vantage implant at two years. Secondary outcomes included radiological alignment, peri-implant complications, and pre- and postoperative patient-reported outcomes. Results. There were 168 patients (171 ankles) included with a mean follow-up of 2.81 years (2 to 4.6) and mean age of 63.0 years (SD 9.4). Of the ten ankles with implant failure (5.8%), six had loosening of the tibial component. In the remaining four failed implants, one was due to periprosthetic joint infection (PJI), one was due to loosening of the talar component, and two were due to loosening of both the tibial and talar components. Seven patients underwent reoperation: irrigation and debridement for superficial infection (n = 4); bone grafting for cysts (n = 2); and open reduction internal fixation (n = 1). Asymptomatic peri-implant lucency/subsidence occurred in 20.1% of ankles, with the majority involving the tibial component (n = 25). There were statistically significant improvements in PROMs in all domains. Conclusion. Short-term results of this implant demonstrate early survival comparable to the reported survivorship of similar low-profile, non-stemmed implants. Radiological lucency occurred more commonly at the tibial component, and revisions occurred primarily due to loosening of the tibial component. Further research is needed to evaluate longer-term survivorship. Cite this article: Bone Joint J 2023;105-B(10):1099–1107

Introduction. Today TKR is considered one of the most successful operative procedures in orthopedic surgery. Nevertheless, failure rates of 2 – 10% depending on the length of the study and the design are still reported. This provides evidence for further development in knee arthroplasty. Particularly the oxide ceramics used now in THA show major advantages due to their excellent tribological properties, their significantly reduced third-body wear as well as their high corrosion resistance. A further advantage of ceramic materials is their potential use in patients with metal allergy. Metallic wear induces immunological reactions resulting in hypersensitivity, pain, osteolysis and implant loosening. The purpose of our study was to examine the safety of the tibial component of a novel all-ceramic TKR. Materials and Methods. We tested the tibial components of the primary knee implant BPK-S Integration Ceramic. Both the tibial and the femoral component consist of BIOLOX®delta ceramic The standards ISO 14879-1 and ASTM F1800-07 describe the test set-up for the experimental fatigue strength testing of tibial components from knee implants. We conducted the testing with a significantly increased maximum load of 5,300 N (900 N are required). A final burst strength test was carried out after the fatigue load testing in the same embedding and with the same test set-up. Results. No specimen failed during fatigue load testing. The subsequent post-fatigue burst strength testing showed a maximum strength against fracture of at least 9.7 kN for size 3 and at least 12.1 kN for size 6. Discussion. The good results of the strength testing of the tibial component of the BPK-S Integration Ceramic tibial plateau supported the good initial clinical outcome without any implant specific complications of this knee design. Further clinical studies have to show if this design fulfills the high expectations over long periods of time

Abstract. Introduction. After remodelling, loss of bone density beside the keel of cementless UKR tibial components has been observed as a potential cause of concern. How this affects patient-reported outcomes, and further clinical implications, is unclear. This study aims to assess the effect of cementless UKR implantation on tibial bone density, and to explore its relationship to patient demographics and outcomes. Method. This prospective study assesses 115 anterior-posterior radiographs from cementless UKR postoperatively and five years after surgery. Grey values from nine regions around each keel were collected and standardised to enable inter-radiograph comparison. Change between the post-operative and 5-year radiographs (indicating bone density) was calculated, and effect on 5-year patient demographics and pain and functional outcomes was assessed. Repeat measurements were performed by two operators to assess reliability. Results. There was excellent inter-operator correlation. There was increased bone density directly below the keel (9.1% vs 3.3%: p<0.0001), and reduced density beside the keel (−5.9% vs -1.0%, p<0.0001); comparisons to adjacent regions. Overall remodelling was significantly greater in smaller tibias (p=0.006), and females (p=0.01). Remodelling was unrelated to outcomes (OKS, ICOAP-A/B, TAS), age, and BMI. Conclusion. Remodelling patterns suggest increased loading below and decreased loading adjacent to the tibial keel. Remodelling is greater in smaller tibias and females. Remodelling is not related to any patient-reported pain or function five years after surgery, suggesting that remodelling is successful in removing any mechanical source of bone pain. Therefore, clinicians viewing such remodelling patterns can ignore them as they are of no consequence

The biomechanics of the patellofemoral joint can become disturbed during total knee replacement by alterations induced by the position and shape of the different prosthetic components. The role of the patella and femoral trochlea has been well studied. We have examined the effect of anterior or posterior positioning of the tibial component on the mechanisms of patellofemoral contact in total knee replacement. The hypothesis was that placing the tibial component more posteriorly would reduce patellofemoral contact stress while providing a more efficient lever arm during extension of the knee. We studied five different positions of the tibial component using a six degrees of freedom dynamic knee simulator system based on the Oxford rig, while simulating an active knee squat under physiological loading conditions. The patellofemoral contact force decreased at a mean of 2.2% for every millimetre of posterior translation of the tibial component. Anterior positions of the tibial component were associated with elevation of the patellofemoral joint pressure, which was particularly marked in flexion > 90°. From our results we believe that more posterior positioning of the tibial component in total knee replacement would be beneficial to the patellofemoral joint

We prospectively assessed the benefits of using either a range-of-movement technique or an anatomical landmark method to determine the rotational alignment of the tibial component during total knee replacement. We analysed the cut proximal tibia intraoperatively, determining anteroposterior axes by the range-of-movement technique and comparing them with the anatomical anteroposterior axis. We found that the range-of-movement technique tended to leave the tibial component more internally rotated than when anatomical landmarks were used. In addition, it gave widely variable results (mean 7.5°; 2° to 17°), determined to some extent by which posterior reference point was used. Because of the wide variability and the possibilities for error, we consider that it is inappropriate to use the range-of-movement technique as the sole method of determining alignment of the tibial component during total knee replacement

Introduction. Malrotation of the tibial component would lead to various complications after total knee arthroplasty (TKA) such as improper joint kinematics, patellofemoral instability, or excessive wear of polyethylene. However, despite reports of internal rotation of the tibial component being associated with more severe pain or stiffness than external rotation, the biomechanical reasons remain largely unknown. In this study, we used a musculoskeletal computer model to simulate a squat (0°–130°–0° flexion) and analyzed the effects of malrotated tibial component on lateral and medial collateral ligament (LCL and MCL) tensions, tibiofemoral and patellofemoral contact stresses, during the weight-bearing deep knee flexion. Materials and Methods. A musculoskeletal model, replicating the dynamic quadriceps-driven weight-bearing knee flexion in previous cadaver studies, was simulated with a posterior cruciate-retaining TKA. The model included tibiofemoral and patellofemoral contact, passive soft tissue and active muscle elements. The soft tissues were modeled as nonlinear springs using previously reported stiffness parameters, and the bony attachments were also scaled to some cadaver reports. The neutral rotational alignment of the femoral and tibial components was aligned according to the femoral epicondylar axis and the tibial anteroposterior axis, respectively. Knee kinematics and ligament tensions were computed during a squat for malrotated conditions of the tibial component. The tibial rotational alignments were changed from 15° external rotation to 15° internal rotation in 5° increments. The MCL and LCL tensions, the tibiofemoral and patellofemoral contact stresses were compared among the knees with different rotational alignment. Results. For the MCL, the neutral rotated tibial components caused a maximum tension of 67.3 N. However, the 15° internally rotated tibial components increased tensions to 285.2N as a maximum tension [Fig.1]. By contrast, with external rotation of the tibial component, the MCL tensions increased only a small amount. The LCL tension also increased but up to less than half of the MCL value [Fig.2]. The tibiofemoral and patellofemoral contact stresses increased because of a decreased contact area [Fig.3]. Discussion and Conclusion: In this computer simulation, excessive internal rotation in the tibial component increased MCL tensions and patellofemoral and tibiofemoral contact stresses. The current study suggests that increased MCL tensions and patellofemoral and tibiofemoral contact stresses caused by a malrotated tibial component could be one cause of patient complaints and polyethylene problems after TKA

Purpose. To achieve 3D kinematic analysis of total knee arthroplasty (TKA), 2D/3D registration techniques, which use X-ray fluoroscopic images and computer aided design model of the knee implants, have been applied to clinical cases. However, most conventional methods have needed time-consuming and labor-intensive manual operations in some process. In particular, for the 3D pose estimation of tibial component model from X-ray images, these manual operations were carefully performed because the pose estimation of symmetrical tibial component get severe local minima rather than that of unsymmetrical femoral component. In this study, therefore, we propose an automated 3D kinematic estimation method of tibial component based on statistical motion model, which is created from previous analyzed 3D kinematic data of TKA. Methods. The used 2D/3D registration technique is based on a robust feature-based (contour-based) algorithm. In our proposed method, a statistical motion model which represents average and variability of joint motion is incorporated into the robust feature-based algorithm, particularly for the pose estimation of tibial component. The statistical motion model is created from previous a lot of analyzed 3D kinematic data of TKA. In this study, a statistical motion model for relative knee motion of the tibial component with respect to the femoral component was created and utilized. Fig. 1 shows each relative knee motion model for six degree of freedom (three translations and three rotations parameter). Thus, after the pose estimation of the femoral component model, 3D pose of the tibial component model is determined by maximum a posteriori (MAP) estimation using the new cost function introduced the statistical motion model. Experimental results. To validate the feasibility and effectiveness of 3D pose estimation for the tibial component using the proposed method, experiments using X-ray fluoroscopic images of 20 TKA patients under the squatting knee motion were performed. For the creation of correct pose (reference data) and the statistical motion model, we used the 3D pose data which were got by carefully applying previous method to the contour images which spurious edges and noises were removed manually. In order to ensure the validity for the statistical motion model of the proposed method, leave-one-out cross validation method was applied. In the 3D pose estimation of tibial component model, for the only first frame, initial guess pose of the model was manually given. For all images except for the first frame, the 3D pose of the model was automatically estimated without manual initial guess pose of the model. To assess the automation performance, the automation rate was calculated, and the rate was defined as the X-ray frame number of satisfying clinical required accuracy (error within 1mm, 1 degree) relative to all X-ray frame number. As results of the experiments, 3D pose of the tibial component model for all X-ray images except for the first frame was full-automatically stably-estimated, and the automation rate was 80.1 %. Conclusions. The proposed method by MAP estimation introduced the statistical motion model was successfully performed, and did not need labor-intensive manual operations for 3D pose estimation of tibial component. For any figures or tables, please contact authors directly (see Info & Metrics tab above).

Aims. Total knee arthroplasty is an established treatment for knee osteoarthritis with excellent long-term results, but there remains controversy about the role of uncemented prostheses. We present the long-term results of a randomized trial comparing an uncemented tantalum metal tibial component with a conventional cemented component of the same implant design. Methods. Patients under the age of 70 years with symptomatic osteoarthritis of the knee were randomized to receive either an uncemented tantalum metal tibial monoblock component or a standard cemented modular component. The mean age at time of recruitment to the study was 63 years (50 to 70), 46 (51.1%) knees were in male patients, and the mean body mass index was 30.4 kg/m. 2. (21 to 36). The same cruciate retaining total knee system was used in both groups. All patients received an uncemented femoral component and no patients had their patella resurfaced. Patient outcomes were assessed preoperatively and postoperatively using the modified Oxford Knee Score, Knee Society Score, and 12-Item Short-Form Health Survey questionnaire (SF-12) score. Radiographs were analyzed using the American Knee Society Radiograph Evaluation score. Operative complications, reoperations, or revision surgery were recorded. A total of 90 knees were randomized and at last review 77 knees were assessed. In all, 11 patients had died and two were lost to follow-up. Results. At final review all patients were between 11 and 15 years following surgery. In total, 41 of the knees were cemented and 36 uncemented. There were no revisions in the cemented group and one revision in the uncemented group for fracture. The uncemented group reported better outcomes with both statistically and clinically significant (p = 0.001) improvements in knee-specific Oxford and Knee Society scores compared with the cemented group. The global SF-12 scores demonstrated no statistical difference (p = 0.812). Uncemented knees had better radiological analysis compared with the cemented group (p < 0.001). Conclusion. Use of an uncemented trabecular metal tibial implant can afford better long-term clinical outcomes when compared to cemented tibial components of a matched design. However, both have excellent survivorship up to 15 years after implantation. Cite this article: Bone Joint J 2020;102-B(8):1025–1032

Aims. Micromotion of the polyethylene (PE) inlay may contribute to backside PE wear in addition to articulate wear of total knee arthroplasty (TKA). Using radiostereometric analysis (RSA) with tantalum beads in the PE inlay, we evaluated PE micromotion and its relationship to PE wear. Methods. A total of 23 patients with a mean age of 83 years (77 to 91), were available from a RSA study on cemented TKA with Maxim tibial components (Zimmer Biomet). PE inlay migration, PE wear, tibial component migration, and the anatomical knee axis were evaluated on weightbearing stereoradiographs. PE inlay wear was measured as the deepest penetration of the femoral component into the PE inlay. Results. At mean six years’ follow-up, the PE wear rate was 0.08 mm/year (95% confidence interval 0.06 to 0.09 mm/year). PE inlay external rotation was below the precision limit and did not influence PE wear. Varus knee alignment did not influence PE wear (p = 0.874), but increased tibial component total translation (p = 0.041). Conclusion. The PE inlay was well fixed and there was no relationship between PE stability and PE wear. The PE wear rate was low and similar in the medial and lateral compartments. Varus knee alignment did not influence PE wear. Cite this article: Bone Joint Res 2024;13(5):226–236

At least four ways have been described to determine femoral component rotation, and three ways to determine tibial component rotation in total knee replacement (TKR). Each method has its advocates and each has an influence on knee kinematics and the ultimate short and long term success of TKR. Of the four femoral component methods, the author prefers rotating the femoral component in flexion to that amount that establishes a stable symmetrical flexion gap. This judgement is made after the soft tissues of the knee have been balanced in extension. Of the three tibial component methods, the author prefers rotating the tibial component into congruency with the established femoral component rotation with the knee is in extension. This yields a rotationally congruent articulation during weight-bearing and should minimise the torsional forces being transferred through a conforming tibial insert, which could lead to wear to the underside of the tibial polyethylene. Rotating platform components will compensate for any mal-rotation, but can still lead to pain if excessive tibial insert rotation causes soft-tissue impingement. Cite this article: Bone Joint J 2013;95-B, Supple A:140–3

Improper rotation of the femoral and tibial components in total knee arthroplasty may leads to various patellofemoral(PF) complications. As for the femoral component, alignment it to the epicondylar axis of the femur has been a widely used method. The tibial component traditionally has been aligned to the medial 1/3 of the tibial tuberosity. However, there is no consensus concerning how to determine the tibial component rotation. The purpose of the current study is to evaluate the influence rotational alignment of tibial component upon PF joint. We divided the cases to two groups. Group A: 41cases 50knees (OA 34cases, RA16cases). The average age was 69.5(35~84). Group B: 30cases 30knees (OA 25 cases, RA 5cases). The average age was 72.6(59~86). In group A, the anteropostrior (AP) axis was defined as the line connecting the medial 1/3 of tibial tuberosity and the center of PCL attachment. In group B, the line connecting the medial edge of patellar tendon attachment and the center of PCL attachment was defined as AP axis. We measured the PF alignment on postoperative X-rays. Tangential radiographs were used to measure the amount of patellar tilt (tilting angle: TA), subluxation and patellar lateral shift (LS). Group A showed that tilting angle 14±4°, lateral shift 0.3±0. These values of group B were 12±5°,0.2±0.1, respectively. In rotation of tibial component, Insall reported that the landmark in front of tibia was medial 1/3 tibial tuberosity. Akagi et,, al reported that the landmark was midial edge of patellar tendon attachment. This study indicated that the latter had better alignment in patellofemoral joint

Background. Trabecular metal (TM) cones are designed to fill up major bone defects in total knee arthroplasty. Tibial components can be implanted in combination with a stem, but it is unclear if this is necessary after reconstruction with a TM cone. Implanting a stem may give extra stability, but may also have negative side-effects. Aim of this study was to investigate stability and strain distribution of a tibial plateau reconstruction with a TM cone while the tibal component is implanted with and without a stem, and whether prosthetic stability was influenced by bone mineral density (BMD). Methods. Tibial revision arthroplasties were performed after reconstruction of an AORI 2B bone defect with TM cones. Plateaus were implanted in seven pairs of cadaveric tibiae; of each pair, one was implanted with and the other without stem. All specimens were loaded to one bodyweight alternating between the medial and lateral tibia plateau. Implant-bone micro motions, bone strains, BMD and correlations were measured and/or calculated. Results. Tibial components without a stem showed only more varus tilt (difference in median 0.14 degrees (P<0.05), but this was not considered clinically relevant. Strain distribution did not differ. BMD had only an effect on the anterior/posterior tilt ρ:-0.72 (P<0.01). Conclusions. Tibial components, with or without a stem, which are implanted after reconstruction of major bone defects using TM cones produce very similar biomechanical conditions in terms of stability and strain distribution. Additional stem extension of the tibial component may not be required after reconstruction of major bone defects using TM cones. Level of evidence. IIb. Disclosures. The department of Orthopaedics, University of Groningen, University Medical Center Groningen has received direct funding from the Anna Fonds (Oegstgeest, NL). Zimmer (Warsaw, IN, USA) has provided the instrumentation and tools for this study. The department of Orthopaedics, University of Groningen, University Medical Center Groningen receives research institutional support from InSpine (Schiedam, NL) and Stryker (Kalamazoo, Mich. USA). One of the authors (ALB) will be and has been paid as a consultant by Zimmer (Warsaw, IN, USA) for purposes of education and training in knee arthroplasty

Objectives. All Polyethylene Tibial components in Total Knee Arthroplasty have been in use for some years, studies showing equivalent results to Total Knee Arthroplasty (TKA) with metal-backed Tibial components at 10 years have shown no significant difference between the two on radiostereometric analysis and revision rates[1]. Post operative patient outcome data using standard metal-backed Tibial components is widely reported in the literature. This study is looking at patient outcomes following All-polyethylene tibial component TKA. We hypothesize that using standard patient outcome measures, an improvement comparable with that expected for metal-backed tibial component TKA will be shown with All-polyethylene tibial component TKA. Methods. Between August 2006 and August 2008, 229 all-polyethylene tibial component TKA were implanted at the elective orthopedic unit. The choice of implant was entirely dependent on surgeon's preference. Of the 229 patient's, 225 details were available for review, 27 did not wish to take part in the study and 1 patient died a year following surgery of an unrelated illness. The remaining 197 patients agreed to take part in the study. The patient's were contacted either in person or over the telephone and asked to completed questionnaires for standard knee scoring. These included: the Oxford Knee Score (OKS), the WOMAC Score and the SF-12 Score, both pre-operatively and post operatively. Results. All three Scoring systems used showed an overall improvement post-operatively, as would be reasonably be expected. The results for the OKS, WOMAC and SF-12 all showed an improvement comparable with that expected for metal-backed tibial component TKA. Conclusions. Total Knee Arthroplasty using an all-polyethylene tibial component has been shown with these early results to be a reasonable alternative to metal-backed options offering some advantages. [1,2]

Abstract. Objective. Up to 20% of patients can remain dissatisfied following TKR. A proportion of TKRs will need early revision with aseptic loosening the most common. The ATTUNE TKR was introduced in 2011 as successor to its predicate design The PFC Sigma (DePuy Synthes, Warsaw, In). However, following reports of early failures of the tibial component there have been ongoing concerns of increased loosening rates with the ATTUNE TKR. In 2017 a redesigned tibial baseplate (S+) was introduced, which included cement pockets and an increased surface roughness to improve cement bonding. Given the concerns of early tibial loosening with the ATTUNE knee system, this study aimed to compare revision rates and those specific to aseptic loosening of the ATTUNE implant in comparison to an established predicate as well as other implant designs used in a high-volume arthroplasty centre. Methods. The Attune TKR was introduced to our unit in December 2011. Prior to this we routinely used a predicate design with an excellent long-term track record (PFC Sigma) which remains in use. In addition, other designs were available and used as per surgeon preference. Using a prospectively maintained database, we identified 10,202 patients who underwent primary cemented TKR at our institution between 01/04/2003–31/03/2022 with a minimum of 1 year follow-up (Mean 8.4years, range 1–20years): 1) 2406 with ATTUNE TKR (of which 557 were S+) 2) 4652 with PFC TKR 3) 3154 with other cemented designs. All implants were cemented using high viscosity cement. The primary outcome measures were all-cause revision, revision for aseptic loosening, and revision for tibial loosening. Kaplan-Meier survival analysis and Cox regression models were used to compare the primary outcomes between groups. Matched cohorts were selected from the ATTUNE subsets (original and S+) and PFC groups using the nearest neighbor method for radiographic analysis. Radiographs were assessed to compare the presence of radiolucent lines in the Attune S+, standard Attune, and PFC implants. Results. At a mean of 8.4 years follow-up, 308 implants underwent revision equating to 3.58 revisions per 1000 implant-years. The lowest risk of revision was noted in the ATTUNE cohort with 2.98 per 1000-implant-years where the PFC and All Other Implant groups were 3.15 and 4.4 respectively. Aseptic loosing was the most common cause for revision across all cemented implants with 76% (65/88) of involving loosening of the tibia. Survival analysis comparing the ATTUNE cohort to the PFC and All Other Cemented Implant cohorts showed no significant differences for: all-cause revision, aseptic loosening, or tibial loosening (p=0.15,0.77,0.47). Radiolucent lines were detected in 4.6%, 5.8%, and 5.0% of the ATTUNE S+, standard ATTUNE, and PFC groups respectively. These differences were not significant. Conclusion. This study represents the largest non-registry review of the original and S+ ATTUNE TKR in comparison to its predicate design as well as other cemented implants. There appears to be no significant increased revision rate for all-cause revision or aseptic loosening. Radiographic analysis also showed no significant difference in peri-implant radiolucency. It appears that concerns of early loosening may be unfounded. Declaration of Interest. (a) fully declare any financial or other potential conflict of interest

Introduction. Tibial component malrotation is one of the commonest causes of pain and stiffness following total knee arthroplasties, however, the assessment of tibial component malrotation on imaging is not a clear-cut. Aim. The objective of this study was to assess tibial component rotation in cases with pain following total knee replacement using MRI with metal artifact reduction technique. Methods. In 35 consecutive patients presented to our clinic between January 2016 and April 2017 with persistent unexplained moderate to severe pain for at least 6 months following total knee arthroplasties after exclusion of infection, MRI evaluation of tibial component rotation using O-MAR technique-(Metal Artifact Reduction for Orthopedic implants) to improve visualization of soft tissue and bone by reducing artifacts caused by metal implants- was done according to the technique of Berger et al. Results. 25 cases showed internal rotation of tibial component, 5 cases showed neutral rotation, 5 cases showed external rotation with presence of abnormal intraarticular fibrous bands. Conclusion. Two main conclusions are obtained from this study:. Firstly: Internal rotation of tibial component must be excluded in all cases of persistent pain following total knee replacement. Secondly: Magnetic resonance imaging with the newly developed metal artifact reduction techniques is a very useful tool in evaluating cases of unexplained pain following total knee replacement

This prospective study compares the outcome of 157 hydroxyapatite (HA)-coated tibial components with 164 cemented components in the ROCC Rotating Platform total knee replacement in 291 patients. The mean follow-up was 7.6 years (5.2 to 11). There were two revisions for loosening: one for an HA-coated and one for a cemented tibial component. Radiological evaluation demonstrated no radiolucent lines with the HA-coated femoral components. A total of three HA-coated tibial components exhibited radiolucent lines at three months post-operatively and these disappeared after three further months of protected weight-bearing. With HA-coated components the operating time was shorter (p <  0.006) and the radiological assessment of the tibial interface was more stable (p < 0.01). Using revision for aseptic loosening of the tibial component as the end point, the survival rates at nine years was identical for both groups at 99.1%. Our results suggest that HA-coated components perform at least as well as the same design with cemented components and compare favourably with those of series describing cemented or porous-coated knee replacements, suggesting that fixation of both components with hydroxyapatite is a reliable option in primary total knee replacement

Background. Total knee prostheses are continually being redesigned to improve performance, longevity and closer mimic kinematics of the native knee. Despite continued improvements, all knee implants even those with proven design features, have failures. We identified a cohort of patients with isolated tibial component failures that occurred in a popular and successful knee system. Our purpose was to (1) characterize the observed radiographic failure pattern; (2) investigate the biologic response that may contribute to the failure; and (3) to determine if the failure mechanism was of a biological or a mechanical nature. Methods. Twenty-one knees from 19 patients met the inclusion criteria of having isolated tibial component failure in a commonly used knee implant system. Radiographs from the primary and revision knee surgery were analyzed for implant positioning and failure pattern, respectively. Inflammatory biomarkers IL-1β, IL-6 and TNF-α were available in 16/21 knees and peripheral CD14. +. /16. +. monocytes were measured in 10 of the above mentioned 16 knee revisions. Additionally, white blood cell (WBC) count, erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) were measured to rule out infection as the cause of the cytokine upregulation. Results. Radiograph findings demonstrated that all of the 21 tibial components were implanted in either neutral or 2–3° varus position, none of the revisions were implanted in valgus (figure 1). All tibias showed obvious radiographic loosening and failed into varus. The inflammatory biomarkers IL-1b, IL-6, & TNF-a were negative. WBC, ESR, CRP were normal. Peripheral CD14+/16+ and total CD16+ monocytesmeasurements were consistent with previous findings of patients with osteoarthritis (figure 2). Conclusions. The findings supported a mechanical failure mechanism rather than that of a wear debris induced inflammatory pattern. The loosening, collapse and debonding from the cement may have been related to the implantation technique, stresses due to rotational freedom of the implant, or patient characteristics/behavior. For any figures or tables, please contact authors directly (see Info & Metrics tab above).

Introduction. Stiffness postTotal Knee Replacement (TKR) is a common, complex and multifactorial problem. Many reports claim that component mal-rotation plays an important role in this problem. Internal mal-rotation of the tibial component is underestimated among surgeons when compared to femoral internal mal-rotation. We believe the internal mal- rotation of thetibial component can negatively affect the full extension of Knee. We performed an in-vivo study of the impact of tibial internal mal-rotation on knee extension in 31 cases. Method. During TKR, once all bony cuts were completed and flexion/extension gaps balanced, we assessed the degree of knee extension using the trial component in the setting of normaltibial rotation and with varying degrees of internal rotation (13–33°, mean 21.2±4.6°). Intra-operative lateral knee X-ray was done to measure the degree of flexion contracture in both groups. We also compared the degree of flexion contracture between CR and PS spacers. Results. The average degree of knee flexion contracture with normal rotation of the tibial component was 0.7±4.1° (range:-9 to 10), whereas after tibial internal rotation was 7.3±4.6° (range:-1 to 23)(P – value:0.001). The increase in the flexion contracture deformity was higher with PS spacer (7.18±2.61) than with CR spacers (5.22±2.05). Conclusion. The internal mal-rotation of the tibial component limits the ability of the tibia to externally rotate on the femur, thereby limiting full knee extension and leading to flexion contracture

[Introduction]. One of the modern design total knee arthroplasty (TKA) system, the NexGen Legacy posterior-stabilized (LPS) Flex prosthesis, has been in use at our hospital since 2001. Between 2006 and 2011, NexGen LPS-Flex primary TKA were mainly performed in combination with a cemented short-keeled minimally invasive version tibial tray (MIS tibial component) instead of the traditional NexGen stemmed tibial tray. We observed some cases required early revision of isolated tibial component in primary TKA performed in this period. Therefore, our objectives were to report the series of this revision cases and to consider this failure mechanism. [Patients & Methods]. A total of 526 primary TKAs were performed using a NexGen LPS-Flex prosthesis and MIS tibial component during five-year period at our hospital. The mean age was 74 years at the time of the index procedure. We assessed revision rate of this tibial tray in this study and described clinical course of the revision cases. We also examined the clinical and radiographic features which could be associated with the failure. [Results]. The mean duration of follow-up was 2.5 years and there were 13 knees received tibial component revision during this period. Twelve knees were diagnosed with osteoarthritis and one knee with rheumatoid arthritis. The duration between primary TKA and revision averaged at 3.3 years, and the mean age at the second procedure was 67 years. TKAs were performed without applying the tibial central extension stem in all 13 knees, and thick polyethylene insert like 17 or 20 mm were selected for seven and 14 mm for five of 13 knees, that were the typical features on the primary TKA. Postoperative course of all 13 cases was uneventful and 10 of 13 knees achieved deep knee flexion over at 125 degrees. Prerevision radiographs showed characteristic pattern with tibial tray debonding at the cement-implant interface and subsidence into varus and flexion in all 13 knees. In all cases, intraoperative findings revealed a grossly loose tibial component with most of the cement mantle still attached to the bone. No case exhibited signs of macroscopic polyethylene wear and femoral component loosening. [Discussion]. The most common reason for failure of TKA is infection followed by implant loosening, polyethylene wear, and instability. Several studies document survival rates of over 90% up to 20 years with modern TKA designs using a cemented stemmed tibial component. Although failure of the tibial component was more prevalent in some early TKA designs, in recent years, failure of tibial fixation has been a rare cause of revision. Our experience with early aseptic loosening of this tibial component has suggested the low-profile design with no central stem as a cause for accelerated failure. Furthermore, other factors associated with increased this failure could include a thicker insert and postoperative achievement of high flexion

Purpose. Medial tibial condylar fractures (MTCFs) are rare but a serious complication after unicompartmental knee arthroplasty (UKA). The reasons for MTCFs was thought to be associated with the surgical procedures that are the halls for the guide pins, extended cut of the posterior tibial cortex, an incorrect positioning of the tibial keel groove, and an excessive force application when placing the tibial component. However, the relationship between MTCFs and the alignment of the tibial component has not been proven. The purpose of the study was to investigate the effect of the tibial component alignment to the MTCFs using the finite element method (FEM). Materials and Methods. We used three-dimensional (3D) image model of the tibia (Sawbones: Washington, US) on the FEM analysis software (ANSYS Design Space ver. 12, Tokyo, Japan). We measured the bone stresses in the 3D image model of the tibia at the site of the medial metaphyseal cortex and the anterior/posterior cortex. The tibial component was placed 0°, 3°varus, 3°valgus, 6°varus, and 6° valgus relative to the tibial anatomical axis in the coronal plane (Figure 1). In sagittal plane, tibial component was positioned 7° posterior inclination relative to the tibial anatomical axis. And, making an additional vertical groove at the posterior cortex by the extended sagittal saw cut of 2° and 10° posterior inclination, the impact of posterior cortical bone stress was evaluated (Figure 2). A load of 900 N was applied to the center of the tibial component parallel to the tibial axis, the maximum bone stress was subsequently calculated. Furthermore, to evaluate the stress distribution, we calculated the bone mass of the 3D bone model below the tibia component under the various alignment of the tibial component (Figure 3). Results. The bone stress at the medial metaphyseal cortex and the anterior cortex did not change depending on the alignment of the tibial component (Figure 4). When the tibial component was placed varus, the bone stress at the posteiror cortex decreased. By contrast, the valgus position of the tibial component increased the bone stress. An extended sagittal saw cut increased the bone stress depending on the depth of the groove. The bone mass of the tibia below the tibial component decreased as positioning the tibial component valgus. Conclusions. Surgeons should be aware of the potential pitfalls of valgus alignemnt of the tibial component and an extended sagittal saw cut, because this can lead to increased risk of the MTCFs

Purpose: To evaluate the effects of underhanging/overhanging tibial components on clinical outcome following the Oxford unicompartmental knee arthroplasty (UKA), and to identify an acceptable sizing limit. Method: One hundred and sixty-three knees which had undergone the Phase 3 medial Oxford UKA (Biomet, Swindon) were measured. Based on five-year post-operative radiographs, they were divided into groups with tibial component underhang (n=38), none or minimal overhang of less than three millimetres (n=121), and a group with overhang equal to or in excess of three millimetres (n=13). Clinical outcome was assessed by changes in the twelve-question Oxford Knee Score (ΔOKS) and pain score (ΔPS) component (questions 1,4,5,8,9) from pre-operative assessment to five years following surgery. Results: At five years after surgery, ΔOKS was significantly worse in the overhang group compared to both the neutral and underhang groups (p=0.015, and p=0.028 respectively). ΔPS was also shown to be significantly worse between the overhang and the neutral group (p=0.026 respectively). Conclusion: Appropriate sizing of the tibial component is essential to optimise load bearing in total knee arthroplasty. In UKA such sizing is critical due to halving of the bony support for the tibial component and the lack of room for a large stem. Excessive undersizing of the prosthesis may lead to subsidence and loosening, whilst excessive overhanging may cause local soft tissue irritation and pain. This study demonstrates that medial overhang of less than three millimetres for the tibial component is acceptable in the Oxford UKA. Excessive overhang equal to this or more results in significantly worse ΔOKS and ΔPS. However, no difference in the five year ΔOKS and ΔPS was demonstrated between underhang and the other two groups in this study

Introduction. Stiffness post Total Knee Replacement (TKR) is a common, complex and multifactorial problem. Many reports claim that component mal-rotation plays an important role in this problem. Internal mal-rotation of the tibial component is underestimated among surgeons when compared to femoral internal mal-rotation. We believe the internal mal-rotation of the tibial component can negatively affect the full extension of Knee. We performed an in-vivo study of the impact of tibial internal mal-rotation on knee extension in 31 cases. Method. During TKR, once all bony cuts were completed and flexion/extension gaps balanced, we assessed the degree of knee extension using the trial component in the setting of normal tibial rotation and with varying degrees of internal rotation (13–33°, mean 21.2±4.6°). Intra-operative lateral knee X-ray was done to measure the degree of flexion contracture in both groups. We also compared the degree of flexion contracture between CR and PS spacers. Results. The average degree of knee flexion contracture with normal rotation of the tibial component was 0.7±4.1° (range: −9 to 10), whereas after tibial internal rotation was 7.3±4.6° (range: −1 to 23) (P – value:0.001). The increase in the flexion contracture deformity was higher with PS spacer (7.18±2.61) than with CR spacers (5.22±2.05). Conclusion. The internal mal-rotation of the tibial component limits the ability of the tibia to externally rotate on the femur, thereby limiting full knee extension and leading to flexion contracture

Tibial component loosening is an important failure mode in unicompartmental knee arthroplasty (UKA) which may be due to the 6–8 mm of bone resection required or the limited surface area. To address component loosening and fixation, a new Early Intervention (EI) design is proposed which reverses the traditional material scheme between femoral and tibial components. That is, the EI design consists of a plastic inlay component for the distal femur and a thin metal plate for the proximal tibia. With this reversed materials scheme, the EI design requires minimal tibial bone resection compared to traditional UKA to preserve the dense and stiff bone in the proximal tibia. This study investigated, by means of finite element (FE) simulations, the potential advantages of a thin metal tibial component compared with traditional UKA tibial components, such as an all-plastic inlay or a metal-backed onlay. We hypothesized that an EI component would produce comparable stress, strain, and strain energy density characteristics to an intact knee and more favorable values than UKA components. Indeed, the finite element results showed that an EI design reduced stresses, strains and strain energy density in the underlying support bone compared to an all-plastic UKA component. Analyzed parameters were similar for an EI and a metal-backed onlay, but the EI component had the advantage of minimal resection of the stiffest bone

We compared the performance of uncemented trabecular metal tibial components in total knee replacement with that of cemented tibial components in patients younger than 60 years over two years using radiostereophotogrammetric analysis (RSA). A total of 22 consecutive patients (mean age 53 years, 33 to 59, 26 knees) received an uncemented NexGen trabecular metal cruciate-retaining monobloc tibial component and 19 (mean 53 years, 44 to 59, 21 knees) a cemented NexGen Option cruciate-retaining modular tibial component. All the trabecular metal components migrated during the initial three months and then stabilised. The exception was external rotation, which did not stabilise until 12 months. Unlike conventional metal-backed implants which displayed a tilting migration comprising subsidence and lift-off from the tibial tray, most of the trabecular metal components showed subsidence only, probably due to the elasticity of the implant. This pattern of subsidence is regarded as being beneficial for uncemented fixation

It is very important for implanting tibial component to prevent bearing dislocation in Oxford UKA. One of the keys is accurate rotational position of tibia. But the problem remains what is accurate rotation of tibia in UKA. Oxford Signature decided the rotation of tibia component from MRI images. We measured the component rotation of tibia using CT after operation. Patients and Methods. 14 patients were operated by Oxford Signature and 11 patients were operated by Microplasty method. Patients were examined by CT 2 or 3 weeks later after operation. We compared component axis of tibia and A-P axis by best fit circle, Akagi's line. Results. In Oxford Signature group, component angle were 7.1 degree external rotation compared with A-P axis by best fit circle and were 3.6 degree external rotation compared with Akagi's line. In Microplasty group, component angle were 8.1 degree external rotation compared with A-P axis by best fit circle and were 3.8 degree external rotation compared with Akagi's line. Discussion. It is difficult to decide accurate position of tibial component for UKA. The A-P axis by best fit circle and Akagi's line are reliable methods for tibial axis in TKA. We examined component axis of Signature Oxford and Microplasty, these were same tendency toward external rotation

Accurate quantitative measurements of micromovement immediately after operation would be a reliable indicator of the stability of an individual component. We have therefore developed a system for measuring micromovement of the tibial component using three non-contact displacement transducers attached to the tibial cortex during total knee arthroplasty (TKA). Using this system we measured the initial stability in 31 uncemented TKAs. All the tibial components were fixed by a stem and four screws. The initial stability was defined as the amount of displacement when a load of 20 kg was applied. The mean subsidence was 60.7 μm and the mean lift-off was 103.3 μm. We also studied the migration of the tibial component using roentgen stereophotogrammetric analysis (RSA) for up to two years after operation. Most migration occurred during the first six months, after which all prostheses remained stable. We defined migration as the maximum total point motion (MTPM) at two years after operation. The mean migration was 1.29 mm at two years. Our results show that there was a significant correlation between the initial stability and migration (p < 0.05) and emphasise the importance of the initial stability of the tibial component

Introduction. Tibial component malrotation is associated with pain, stiffness and altered patellofemoral kinematics in total knee arthroplasty (TKA). However, accurately measuring tibial component rotation following TKA is difficult. Proposed protocols utilizing computed tomography (CT) are not well validated and can be time consuming. This study aimed to; 1) Validate and compare the reproducibility of the Berger (2D-CT) and Mayo (3D-CT) protocols; 2) Validate a simple, and potentially rapid screening measurement using an anatomical distance on 2D axial CT- the Centre of Tibial Tray to Tibial Tubercle (CTTT) distance. Methods. Rotational alignment of 70 TKA patients were evaluated by 3 independent observers using the Berger, and Mayo protocols, which have been previously described, and a new CTTT protocol (Figure 1). The inter and intra-rater interclass correlation coefficients (ICC's), mean difference between measurements and the mean measurement times were calculated. Linear regression analysis was performed to give a coefficient of determination (R2). Results. The intra-rater reliability for all 3 protocols was rated as “very good” (Mayo 0.96, Berger 0.85 and CTTT 0.85). The inter-rater reliability for the Mayo and the Berger method was rated as “very good” (0.87 and 0.83 respectively), the CTTT was rated as “good” (0.79). The Mayo method had a lower mean difference in intra-rater measurements than the Berger method (1.42° vs 2.60° p= <0.01). Comparing the CTTT to the Mayo method produced an R2 value of 0.73 indicating strong correlation. As a screening tool, 92% of patients with CTTT ≤ 6mm had < 9° of tibial component internal rotation (IR), and 93% of patients with a CTTT ≥ 10mm had ≥ 9° IR. The Mayo method takes 3 minutes, 29 seconds; Berger method: 2 minutes, 5 seconds; CTTT method: 39 seconds to perform. Conclusion. 3D CT is the gold standard for formally determining tibial component rotational alignment. The CTTT has the strongest correlation to the Mayo method, and is the least time consuming. The CTTT method can be used as a reliable, simple and rapid screening tool in daily clinical practice to assess tibial component rotational alignment following TKA, prior to formal measurement. For any figures or tables, please contact authors directly

Background. Finite element (FE) models are frequently used in biomechanics to predict the behaviour of new implant designs. To increase the stability after severe bone loss tibial components with long stems are used in revision total knee replacements (TKR). A clinically reported complication after revision surgery is the occurrence of pain in the stem-end region. The aim of this analysis was the development of a validated FE-model of a fully cemented implant and to evaluate the effect of different tibial stem orientations. Methods. A scanned 4th generation synthetic left tibia (Sawbones) was used to develop the FE-model with a virtually implanted fully cemented tibial component. The 500 N load was applied with medial:lateral compartment distributions of 60:40 and 80:20. Different stem positons were simulated by modifying the resection surface angle posterior to the tibias shaft axis. The results were compared with an experimental study which used strain gauges on Sawbones tibias with an implanted tibial TKR component. The locations of the experimental strain gauges were modelled in the FE study. Results. Similar patterns and magnitudes of the predicted and experimentally measured strains were observed which validated the FE-model. An increase of strain at the most distal gauge locations were measured with the stem-end in contact to the posterior cortical bone. More uniform strain distributions were observed with the stem aligned to the intramedullary canal axis. The load distribution of 80:20 shifts the strains to tensile laterally and a large increase of compressive strain in the medial distal tibia. Conclusions. A contributory factor of the clinically reported stem-end pain is possibly the direct effect of contact of the tibial stem-end to the posterior region of the cortical bone. The increased load to the medial tibial compartment is more critical for the development of pain

When performing total knee replacement (TKR), surgeons must select a size of tibial component tray that most closely matches the anatomy of the proximal tibia. As implants are available in a limited range of sizes, it may be necessary to slightly under or oversize the component. There are concerns overhang could lead to pain from irritation of soft tissues, and underhang could lead to subsidence and failure. 154 TKRs at 1- or 5-year follow up were reviewed prospectively. Oxford Knee Score (OKS), WOMAC and SF-12 was recorded along with pain scores. Scaled radiographs were reviewed and grouped into perfect sizing (78 TKRs, 50.6%), underhang in isolation (48 TKRs, 31.1%), minor overhang 1–3 mm (10 TKRs, 6.49%) or major overhang >3 mm (18 TKRs, 11.7%). There was no significant difference in the SF-12 (p=0.356), post-operative OKS (p=0.401) or WOMAC (p=0.466) score. For the OKS, there was no difference for the scores collected at 1 year (p=0.176) or at 5 years (p=0.883). Pre-operative OKS was well matched between the groups (p=0.152). There was no significant difference in the improvement in OKS from pre-operative scores (p=0.662). There was no significant difference in either the OKS or WOMAC pain scores (p=0.237 and 0.542 respectively). There was no significant association of medial overhang with?medial knee pain (p=1.000) or lateral overhang with lateral knee pain (p=0.569) when compared to the group of patients with a well sized tibial component. Our results suggest that tibial component overhang or underhang has no detrimental affect on outcome or pain scores. Surgeons should continue to select the tibial component that most closely fits the rim of the proximal tibia while accepting slight overhang if necessary due to the potential longer-term complications of subsidence and premature failure with an undersized tibial tray

Background. Several studies have reported that tibial component in varus alignment can worsen the survivorship of medial unicompartmental knee arthroplasty (UKA). On the other hand, Varus/valgus inclination of the tibial component can affect the location of the contact point between femoral and tibial component especially in round on flat bearing surface design. Along with the tibial component inclination, changes in the contact point may also alter the tibial condylar bone stress, which would affect the longevity or complications after UKA. Method. We constructed a validated three-dimensional finite element model of the tibia with a medial component and assessed stress concentrations by changing the tibial component coronal inclinations (squale inclination, 3° and 6° varus, 3° and 6° valgus inclination). We evaluated the Von Mises stress on the medial tibial metaphyseal cortex and the proximal resected surface when a load of 900N was applied on the tibial component surface by two conditions in each inclination models; one is that the loading site is fixed at the mediolateral center of the tibial component (fixed model), and the other is that the loading site is variable depending on the tibial component inclination (variable model) (Fig.1). Result. In variable models, the loading site moved medially 22.8% of the tibial component width as the tibial component inclination changed from 6°varus to 6°valgus. The Von Mises stress concentrations were observed on the medial tibial metaphyseal cortices and on the anterior and posterior corner of the resected surface in all models (Fig.2). Stress concentration was also observed along the medial cortical rim of the resected surface in valgus tibial component inclination of the fixed model and varus inclination of the variable model (Fig.2). The stress on the medial tibial metaphyseal cortices did not markedly change in any inclination of fixed models, but increased in variable models as the tibial component inclination changed from varus to valgus (Fig.3A). The stress on the medial cortical rim of the resected surface increased with varus inclination in the fixed model and decreased with varus inclination in the variable model (Fig.3B). Changes in the Von Mises stress on the anterior and posterior corner of the resected surfaces did not differ between the fixed and variable model. Discussion. Varus inclination of the tibial component has been considered to increase the bone stress in previous studies. However, in the current study, bone stress on the medial metaphyseal cortex and the medial cortical rim of the resected surface conversely decreased in varus inclination when the change of the femorotibial contact point was taken into consideration. Recent opinion has advocated that restoring the constitutive patient's anatomy by compensating cartilage wear is critical in producing the excellent clinical outcome after UKA. Therefore, three to five degrees of anatomical varus inclination of the tibial component would reduce the tibial condylar bone stress and protective against complications such as unknown postoperative pain or tibial component migration. For figures/tables, please contact authors directly.

The aim of this study is to identify the incidence of mal-rotation of TKR components in a group of patients with unexplained knee pain identified from the University of Dundee joint replacement database and compare that group with a group of painless TKRs. 38 of 45 NexGen LPS Total Knee Replacements identified with unexplained pain at a minimum of 1 year following surgery underwent CT scanning to determine rotational alignment. All patients had a Knee Society Pain score of 20 points or less and a mean Visual Analogue Pain Score of greater than 4.0. This group was compared with a control group of 26 TKRs all of which had never reported pain from 1 year post surgery. In the painful group mean femoral component rotation was 2.2° of internal rotation (range 8.8°IR to 3.9°ER, sd 3.6, SEm 0.59) compared to 0.9°IR (range 6.9°IR to 6.8°ER, sd 3.39, SEm 0.67) in the painless group (p= 0.15). In the painful group 21.6% of femoral components were more than 6° internally rotated compared with 7.7% in the painless group however this was not statistically significant (p=0.18). No femoral components in either group were in excessive (over 8 degrees) ER. Tibial component rotation was much more variable than femoral component rotation in both groups particularly in the painful group. Mean tibial component rotation was 4.1°IR (range 37.9°IR to 31.1°ER, sd 14.6, SEm 2.4) in the painful group compared to 2.2°ER (range 8.5°IR to 18.2°ER, sd 6.95, SEm 1.36) in the painless group (p=0.024). 15 tibial components (39.5%) were greater than 10° internally rotated in the painful group whilst no tibial components were more than 10° internally rotated in the pain free group (p< 0.001). In the painful group 7 tibial components (18.4%) were more than 10° externally rotated whilst 4 (15.4%) were in more than 10° ER in the painless group (p=1.00). Overall 22 tibial components (57.9%) were in more than 10° of malrotation in the painful group compared with 4 (15.4%) in the pain free group (p=0.05). Mean rotational mismatch between femoral and tibial components was 1.9° tibial IR (range 39.7° tibial IR to 35.1° tibial ER, sd 16.1, SEm 2.7) in the painful group whilst in the painless group mean rotational mismatch was 3.1 degrees tibial ER (range 10.3° tibial IR to 22.1° tibial ER, sd 8.4, SEm 1.65). This difference was not significant (p=0.12). 16 TKRs (55.3%) had rotational mismatch of more than 10° in the painful group compared to 7 (26.9%) in the control group (p=0.02). We conclude that rotational malalignment is frequent in painful total knee replacements and may be a major cause of pain after TKR. In particular tibial internal rotation is the most frequent alignment error in the painful TKR and appears to play a major role in the aetiology of pain after TKR

Rotational malalignment in total knee arthroplasty (TKA) may lead to several complications. Transepicondylar axis has been accepted for a reference of femoral rotation. In contrast, standard reference of tibial rotation remains controversial. Currently, two techniques are widely used, the anatomical landmarks technique and the range-of-movement (ROM) technique. Fifty-one patients underwent posterior-stabilized TKA with center-post self-align ROM technique for tibial component placement. Laurin view radiograph and computer tomography (CT) were used to assess the prosthetic position. The rotational mismatch between tibial and femoral components was 2.00° ± 0.34° (range, 0.1°-5.8°). All TKA showed a tibiofemoral mismatch within 10° (range, 0.1° −5.8°). Intraoperative evaluation of patellar tracking by no-thumb test and the Laurin view showed normal range in 90%. We concluded that tibial component placement with center-post self-align technique in PS-TKA can produce good patellar tracking with acceptable range of tibiofemoral mismatch

There are basically 4 ways advocated to determine the proper femoral component rotation during TKA: (1) The Trans-epicondylar Axis, (2) Perpendicular to the “Whiteside Line,” (3) Three to five degrees of external rotation off the posterior condyles, and (4) Rotation of the component to a point where there is a balanced symmetric flexion gap. This last method is the most logical and functionally, the most appropriate. Of interest is the fact that the other 3 methods often yield flexion gap symmetry, but the surgeon should not be wed to any one of these individual methods at the expense of an unbalanced knee in flexion. In correcting a varus knee, the knee is balanced first in extension by the appropriate medial release and then balanced in flexion by the appropriate rotation of the femoral component. In correcting a valgus knee, the knee can be balanced first in flexion by the femoral component rotation since balancing in extension almost never involves release of the lateral collateral ligament (LCL) but rather release of the lateral retinaculum. If a rare LCL release is anticipated for extension balancing, then it would be performed prior to determining the femoral rotation since the release may open up the lateral flexion gap to a point where even more femoral component rotation is needed to close down that lateral gap. It is important to know and accept the fact that some knees will require internal rotation of the femoral component to yield flexion gap symmetry. The classic example of this is a knee that has previously undergone a valgus tibial osteotomy that has led to a valgus tibial joint line. In such a case, if any of the first 3 methods described above is utilised for femoral component rotation, it will lead to a knee that is very unbalanced in flexion being much tighter laterally than medially. A LCL release to open the lateral gap will be needed, increasing the complexity of the case. My experience has shown that intentional internal rotation of the femoral component when required is well-tolerated and rarely causes problems with patellar tracking. It is also of interest to note that mathematical calculations reveal that internally rotating a femoral component as much as 4 degrees will displace the trochlear groove no more that 2–3 mm (depending on the FC size), an amount easily compensated for by undersizing the patellar component and shifting it medially those few mm. There are basically 3 ways to determine the proper tibial component rotation during TKA: (1) Anatomically cap the tibial cut surface with an asymmetric tibial component, (2) Align the tibial rotation relative to a fixed anatomic tibial landmark (most surgeons use this method and align relative to the medial aspect of the tibial tubercle), (3) Rotate the tibial component to a point where there is rotational congruency in extension between the femoral and tibial articulating surfaces. This third method must be used with fixed bearing arthroplasties (especially with conforming articulations) to avoid rotational incongruency between the components during weight-bearing that can create abnormal and deleterious torsional forces on posterior stabilised posts, insert tray interfaces and bone-cement interfaces. Rotating platform articulations can tolerate rotational mismatch unless it is to a point where the polyethylene insert rotates excessively and causes symptomatic soft tissue impingement

Between December 1998 and December 1999 twenty-one patients with painful knee arthroplasties underwent assessment by radionuclide arthrography. There were eleven female and ten male patients, with an average age of 60 years at the time of the index procedure. The index procedure was a primary total knee arthroplasty, primary medial unicompartmental knee arthroplasty and revision medial UKA in seventeen, three and one patients respectively. Nineteen arthroplasties were uncemented and two were hybrids. All patients had previously been investigated by clinical examination, serological testing, fluoroscopic AP and lateral radiographs, and Tc99 bone scan with equivocal results. The presence of radionuclide about the tibial stem was considered diagnostic of tibial loosening. Nine patients underwent revision knee arthroplasty. The presence of radionuclide about the tibial stem correctly predicted a loose tibial component in four of five cases. Similarly, the absence of radionuclide about the tibial stem correctly predicted a stable tibial component in four of four cases. In the single misdiagnosed case the tibial component did not have a large central stem, had focal osteolysis about several screws, but remained stable. Radionuclide arthrogram is a useful tool in the investigation of painful knee arthroplasty. Radionuclide about the tibial stem is the key predictor of tibial component loosening

The anterior curve of the tibial plateau cortex represents a realiable and reproducible landmark which may help aligning the tibial component with the femoral component and the extensor mechanism. Few studies analyzed the tibial component rotational alignment during total knee arthroplasty. Malrotation can affect both patello-femoral and tibio-femoral postoperative function. We evaluated the rotational relationship between femur and tibia, and we investigated which tibial landmark consistently matches the rotation of the femoral epicondylar axis in full extension (Fig 1). Axial magnetic resonance images of 124 normal knees (statistical power 1-beta=0.8) were analyzed separately by three authors. Scanograms were obtained with the knee in full extension and with the long axis of the foot (second metatarsal bone) aligned on the neutral sagittal plane. The surgical epicondylar axis was drawn and projected over the proximal tibia and tibial tuberosity slices. Multiple anatomical tibial rotational landmarks were drawn and symmetric tibial component digital templates of different sizes were aligned according to each landmark. Alignment of the virtual tibial components was then compared to that of the projected femoral epicondylar axis (Fig 2). The best antero-posterior line to achieve rotational matching between the components was drawn on the proximal tibia slice of each patient. Results of rotation (positive = external rotation, negative = internal) relative to the epicondylar axis were (Fig 3): (a) Medial third-to the middle third of the tibial tubercle 1.2°+/−5.7, (b) Akagi's line (centre of the posterior cruciate ligament tibial insertion to the most medial part of the tibial tubercle) -11.5+/−6.5, (c) The anterior curved tibial plateau cortex (curve-on-curve matching between the tibial template and the anterior cortex) 1.0+/−2.9. Intraclass correlation coefficient resulted 0.923, 0,881, and 0.949 for the Akagi's line, Middle third of tibial tubercle, and the curve-on-curve reference respectively. The anterior curve of the tibial plateau cortex represents a realiable and reproducible landmark which may help aligning the tibial component with the femoral component and the extensor mechanism (Fig 4, 5)

Background. Although early TKA designs were symmetrical, during the past two decades TKA have been designed to include asymmetry, pertaining to either the trochlear groove, femoral condylar shapes or the tibial component. More recently, a new TKA was designed to include symmetry in all areas of the design, in the hopes of reducing design and inventory costs. Objective. The objective of this study was to determine the in vivo kinematics for subjects implanted with this symmetrical TKA during a weight-bearing deep knee bend activity. Methods. In vivo deep knee bend (DKB) kinematics for 21 subjects implanted with symmetrical posterior cruciate sacrificing (PCS) fixed bearing TKA were obtained using fluoroscopy. A 3D-to-2D registration technique was used to determine each subjects anteroposterior translation of lateral (LAP) and medial (MAP) femoral condyles and tibiofemoral axial rotation and their weight-bearing knee flexion. Results. During the DKB, the average maximum weight-bearing flexion was 111.7° ± 13.3°. On average, from full extension to maximum knee flexion, subjects experienced 2.5 mm ± 2.0 mm femoral rollback on lateral condyle −2.5 mm ± 2.2 mm of medial condyle motion in the anterior direction (Figure 1). This medial condyle motion was consistent for the majority of the subjects with the lateral condyle exhibiting rollback from 0° to 60° of flexion and then an average anterior slide of 0.3 mm from 60° to 90° of flexion. On average, the subjects in this study experienced 6.6° ± 3.3° of axial rotation, with most of rotation occurring in early flexion, averaging 4.9° (Figure 2). Discussion. Although subjects in this study were implanted with a symmetrical TKA, they did experience femoral rollback of the lateral condyle and positive axial rotation. Both of these kinematic parameters were normal-like in pattern, compared to the normal knee in early flexion, but in deeper flexion the pattern of motion varied from the normal knee. Also, the magnitude of posterior femoral rollback and axial rotation revealed similarities to previous fluoroscopy studies on subjects implanted with an asymmetrical TKA design. This was only a single surgeon study, so it is unclear if the results are TKA or surgeon influenced. Therefore, it is proposed that more patients be analyzed having this TKA implanted by other surgeons. For any figures or tables, please contact the authors directly

Introduction The tibial component of a total knee arthroplasty is subjected to eccentric medial and lateral plateau tibial loading during various phases of stance. The resultant coronal planar tilting forces may provoke early subsidence and loosening. The addition of a long non cemented stem is postulated to act as an outrigger, diminishing the rate of aseptic loosening. Methods Two hundred and thirteen primary total knee arthroplasties using proximally cemented tibial components with long non cemented Pressfit stems have been reviewed. Stem lengths varied from 110 mm to 140 mm. Patients were seen at an average of 8.7 years after surgery (two to 13 years) and were assessed using the Knee Society (IKS) pain and function scores, IKS radiographic analysis and Short Form-12 and Western Ontario Macmasters University Osteoarthritis Index (WOMAC questionnaires). Results Average range of motion was 115° at latest follow-up. The average IKS pain and function scores at the time of assessment were 90 and 89 respectively. Radiographic assessment revealed no case of tibial implant loosening. Kaplan-Meier survivorship was 98.6% at 13 years. Conclusions The results lend clinical support to the known theoretical advantages of adding a stem to the tibial component in primary knee arthroplasty. In relation to the conduct of this study, one or more the authors have received, or are likely to receive direct material benefits

Introduction. Proper rotational alignment of the tibial component in total knee arthroplasty (TKA) could be achieved using several techniques. The self adjustment methodology allows the alignment of the tibial component under the femoral component after several flexion-extension movements. Our hypothesis was that this technique allowed a posterior tibial component alignment parallel to the femoral component posterior bicondylar axis. The aim of this study was to access this hypothesis using a post-operative CT-scan study. Materials and Methods. This prospective CT-scan study involved 94 TKA. Theses TKA were divided in two groups: group1: 50 knees with a pre-operative genu varum deformity (mean HKA: 172.2°), operated using a medial parapatellar approach, and group 2: 44 knees with a preoperative valgus deformity (mean HKA: 188.7°), operated using a lateral parapatellar approach. Four measures were done on each post-operative CT-scan: angle between anatomical transepicondylar axis and femoral component posterior bicondylar axis (FCPCA), angle between FCPCA and tibial component marginal posterior axis, angle between tibial component marginal posterior axis and bony tibial plateau marginal posterior axis (BTPMPA), angle between transepicondylar axis and tibial component marginal posterior axis. Each measure was repeated, after one month by the same independent observer. Statistical evaluation used non-parametric Wilcoxon–Mann–Whitney test to compare each group of measures, and intraobserver reproducibility was assessed using ANOVA test, with an error rate of 5%. Results. Intraobserver measurements were reproducible. Mean FCPCA was to 3,1° (SD:1,91) in group 1 and 4,7° (DS: 2,96) in group 2. Tibial component was positioned in external rotation in both groups, in relation to FCPCA: (group 1: mean angle: 0,7° (SD:4,45), group 2: mean angle: 0,9° (SD:4,53)) and in relation to BTPMPA: (group1: mean angle: 6,1° (SD: 5,85); group2: mean angle: 12,5° (SD: 8,6)). There was no statistical difference between these two groups. Tibial component was positioned in internal rotation in relation to anatomical transepicondylar axis: (Group1: mean angle: 1,9° (SD: 4,93); group 2: mean angle: 3° (SD: 4.38)). Discussion. By using the self adjustment technique, tibial component is aligned parallel to the femoral component regardless of the initial frontal deformity and the surgical approach. However, there was a difference in tibial component axis and BTPMPA, between the two groups. This difference should be explained by the difference in morphology of the tibial plateau bone in knee with genu valgum deformity. The self adjustment technique is a reliable method to obtain a proper rotational alignment of the tibial component in TKA

We studied the quality of fixation of the tibial component using radiostereometric analysis (RSA) in 40 patients who had undergone a cemented Freeman-Samuelson total knee arthroplasty. They were prospectively randomised to either a stemmed metal-backed (MB) or non-stemmed all-polyethylene (AP) tibial component. The articulating geometry of the implants was identical, as was the operative technique and the postoperative regime. The study showed no complications of fixation using AP tibial components, and the migration was the same as that of their metal-backed counterparts. There was no bony collapse or increased subsidence of any part of the tibial component or increased incidence of radiolucent lines in the knees with AP components. Most AP implants were stable between one and two years after surgery, a finding known to be of positive prognostic significance when predicting future aseptic loosening

This study used CT analysis to determine the rotational alignment of 39 painful and 26 painless fixed-bearing total knee replacements (TKRs) from a cohort of 740 NexGen Legacy posterior-stabilised and cruciate-retaining prostheses implanted between May 1996 and August 2003. The mean rotation of the tibial component was 4.3° of internal rotation (25.4° internal to 13.9° external rotation) in the painful group and 2.2° of external rotation (8.5° internal to 18.2° external rotation) in the painfree group (p = 0.024). In the painful group 17 tibial components were internally rotated more than 9° compared with none in the painfree group (p < 0.001). Additionally, six femoral components in the painful group were internally rotated more than 6° compared with none in the painfree group (p = 0.017). External rotational errors were not found to be associated with pain. Overall, 22 (56.4%) of the painful TKRs had internal rotational errors involving the femoral, the tibial or both components. It is estimated that at least 4.6% of all our TKRs have been implanted with significant internal rotational errors

Introduction: Concerns of backside wear have made the use of the all polyethylene tibial component a viable choice in primary total knee arthroplasty. This study compares the results of two groups, one with a modular tibial component and one with an all polyethylene tibial component. Materials: Between 1986 and 1995, 670 patients underwent total knee arthroplasty using one design with a PCL retaining prosthesis. 500 patients in this group were implanted with a modular tibial component and 170 an all polyethylene tibial tray. The groups were comparable in sex and age (74.1 years for the metal trays and 75.8 years for the all polyethylene components.). The average follow up is 83.9 months for the metal tray group and 74.8 months for the all poly tibial group. The arthroplasties were evaluated annually using the Knee Society guidelines. Results: The postoperative Knee Society Score were 74.5 (metal) and 73.9 (all polyethylene). Joint specific scores for the all polyethylene were slightly higher at 89.9 compared to 88.5 for the metal tray group. Revision rates were 1.8% (3 cases in the polyethylene group) and .8% for the metal group (8 cases). The 3 revisions in the all polyethylene group were for late infections while 5 of the 8 in the metal group demonstrated polyethylene wear/osteolysis. Discussion and conclusions: The clinical results of the all polyethylene group are equal the modular tibial tray group. Because of the excellent radiographic results and non-existent mechanical failure rate to date, the all polyethylene group also provides an opportunity to reduce wear debris with subsequent osteolysis

We evaluated the survival of moulded monoblock and modular tibial components of the AGC total knee replacement in patients with rheumatoid arthritis. Between 1985 and 1995, 751 knees with this diagnosis were replaced at our institution. A total of 256 tibial components were of the moulded design and 495 of the modular design. The mean follow-up of the moulded subgroup was 9.6 years (0.5 to 14.7), and that of the modular group 7.0 years (0.1 to 14.7). The groups differed significantly from each other in Larsen grade, cementing of components and patellar resurfacing, but no statistically significant difference between the survival of the components was found (Log rank test, p = 0.91). The cumulative success rate of the moulded group was 96.8% (95% confidence interval 93.6% to 98.4%) at five years and 94.4% (95% confidence interval 90.4% to 96.7%) at ten years, and of the modular group 96.2% (95% confidence interval 94% to 97.6%) and 93.6% (95% confidence interval 89.7% to 96%), respectively. Revision was required in 37 total knee replacements, the main causes were infection, pain, loosening of the tibial component and patellar problems. Survival rates for both components were satisfactory

INTRODUCTION. Cemented total knee arthroplasty (TKA) is a widely accepted treatment for end-stage knee osteoarthritis. During this procedure, the surgeon targets proper alignment of the leg and balanced flexion/extension gaps. However, the cement layer may impact the placement of the component, leading to changes in the mechanical alignment and gap size. The goal of the study was to assess the impact of cement layer on the tibial mechanical alignment and joint gap during cemented TKA. MATERIAL. Computer-assisted TKAs (ExactechGPS®, Blue-Ortho, Grenoble, FR) were performed by two fellowship trained orthorpaedic surgeons on five fresh-frozen non-arthritic pelvis-to-ankle cadaver legs. All the surgeries used a cemented cruciate retaining system (Optetrak Logic CR, Exactech, Gainesville, FL). After the bony resection, the proximal tibial resection plane was acquired by manually pressing an instrumented checker onto the resected tibial surface (resection plane). Once the prosthesis was implanted through standard cementing techniques, the top surface of the implanted tibial component was probed and recorded using an instrumented probe. A best fit plane was then calculated from the probed points and offset by the thickness of the prosthesis, representing the bottom plane of the component (component plane). The deviation of component alignment caused by the cement layer was calculated as the coronal and sagittal projection of the three-dimensional angle between the resection plane and the component plane. The deviation of the component height, reflecting a change in the joint gap, was assessed as the distance between the two planes calculated at the lowest points on the medial and lateral compartments of the proximal tibial surface. Statistical significance was defined as p≤0.05. RESULTS. The differences in alignment and component height between the tibial component placement and the ideal placement based on the bony resection are presented in Table 1. The magnitude of deviation in alignment was 1.2±0.9° for varus/valgus and 1.7±0.7° for posterior slope, with a tendency towards valgus (−0.2±1.6°) and reduced posterior slope (0.6±1.9°). The lateral compartment (2.4±0.9mm) had a generally higher increase in the height of the component compared to the medial compartment (1.0±0.9mm), the difference was close to being statistically significant (p=0.055). DISCUSSION. The finding of this study demonstrated that standard cement fixation during TKA may potentially influence the alignment and position of the tibial component. The formed cement layer generally results in elevated height, slightly more varus tibial alignment (overall limb valgus alignment) and less posterior slope in the implanted component. The results on the alignment are comparable to a previous study by Catani et al. [1]. More than 2°/2mm of deviation was found in the sagittal alignment (2 out of 5 knees), and medial (1 out of 5 knees) and lateral (3 out of 5 knees) component height, which may clinically impact the joint gap [2]. The varus/valgus alignment deviation found was clinically acceptable (≤3°). However when combined with other surgical variables, the accumulated impact on the alignment may warrant more investigation

Restoration of natural range and pattern of motion is the primary goal of joint replacement. In total ankle replacement, proper implant positioning is a major requirement to achieve good clinical results and to prevent instability, aseptic loosening, meniscal bearing premature wear and dislocation at the replaced ankle. The current operative techniques support limitedly the surgeon in achieving a best possible prosthetic component alignment and in assessing proper restoration of ligament natural tensioning, which could be well aided by computer-assisted surgical systems. Therefore the outcome of this replacement is, at present, mainly associated to surgeon's experience and visual inspection. In some of the current ankle prosthetic designs, tibial component positioning along the anterior/posterior (A/P) and medio/lateral axes is critical, particularly in those designs not with a flat articulation between the tibial and the meniscal or talar components. The general aim of this study was assessing in-vitro the effects of the A/P malpositioning of the tibial component on three-dimensional kinematics of the replaced joint and on tensioning of the calcaneofibular (CaFiL) and tibiocalcaneal (TiCaL) ligaments, during passive flexion. Particularly, the specific objective is to compare the intact ankle kinematics with that measured after prosthesis component implantation over a series of different positions of the tibial component. Four fresh-frozen specimens from amputation were analysed before and after implantation of an original convex-tibia fully-congruent three-component design of ankle replacement (Box Ankle, Finsbury Orthopaedics, UK). Each specimen included the intact tibia, fibula and ankle joint complex, completed with entire joint capsule, ligaments, muscular structures and skin. The subtalar joint was fixed with a pin protruding from the calcaneus for isolating tibiotalar joint motion. A rig was used to move the ankle joint complex along its full range of flexion while applying minimum load, i.e. passive motion. In these conditions, motion at the ankle was constrained only by the articular surfaces and the ligaments. A stereofotogrammetric system for surgical navigation (Stryker-Leibinger, Freiburg, Germany) was used to track the movement of the talus/calcaneus and tibial segments, by using trackers instrumented with five active markers. Anatomical based kinematics was obtained after digitization by an instrumented pointer of a number of anatomical landmarks and by a standard joint convention. The central point of the attachment areas of CaFiL e TiCaL was also digitised. Passive motion and ankle joint neutral position were acquired, and the standard operative technique was performed to prepare the bones for prosthesis component implantation. The final component for the talus was implanted, the tibial component was initially positioned well in front of the nominal right (NR) position, the meniscal bearing was instrumented with an additional special tracker, and passive motion was collected again in passive flexion. Data collection was repeated for progressively more posterior locations for the tibial component, for a total of six different locations along the tibial A/P axis: three anterior (PA), the NR, and two more posterior (PP), approximately 3 to 5 mm far apart each. The following three-dimensional kinematics variables were analyzed: the three anatomical components of the ankle joint (talus-to-tibial) rotation (dorsi/plantar flexion, prono/supination and internal/external rotation respectively in the sagittal, frontal and transverse planes), the meniscal bearing pose with respect to the talar and tibial components, the ‘ligament effective length fraction’ as the ratio between the instantaneous distance between the ligament attachment points and the corresponding maximum distance, and the instantaneous and mean helical axes in the tibial anatomical reference frame. In all specimens and in all conditions, physiological ranges of flexion, prono/supination and internal/external rotation were observed at the ankle joint. A good restoration of motion was observed at the replaced joint, demonstrated also by the coupling between axial rotation and flexion and the physiological location of the mean helical axis, in all specimens and in most of the component positions. Larger plantar- and smaller dorsi-flexion were observed when the tibial component was positioned more anteriorly than NR, and the opposite occurred for more posterior positions. In regards to the meniscal bearing, rotations were small and followed approximately the same patterns of the ankle rotations, accounted for the full conformity of the articulating surfaces. Translations in A/P were larger than in other directions, the bearing moving backward in plantarflexion and forward in dorsiflexion with respect to both components. It was observed that the closer to NR the position of the tibial component is, the larger this A/P motion is, accounted mainly to the associated larger range of flexion. The change of CaFiL and TiCaL effective length fraction over the flexion arc was found smaller than 0.1 in three specimens, smaller than 0.2 in the fourth, larger both in more anterior and more posterior locations of the tibial component. The simulated malpositioning did not affect much position and orientation of the mean helical axis in both the transversal and frontal planes. The experimental protocol and measurements were appropriate to achieve the proposed goals. All kinematics variables support the conclusion that the ankle replaced with this original prosthesis behaves as predicted by the relevant computer models, i.e. physiological joint motion and ligament tension is experienced resulting in a considerable A/P motion of the meniscal bearing. These observations are particularly true in the NR postion for the prosthesis, but are somehow correct also in most of the tibial malpositions analysed, in particular those on the back

Tibial component loosening continues to be the most common mode of TKA failure. A debate persists on the dependence of mobilisation of this component on the equilibrium between mechanical load transfer and counterbalancing bone resistance. The aim of the present work is to study the in-vivo kinematics of TKA and to relate it with the degree of posterior slope with which the tibial component was implanted for two prosthesis designs with congruent polyethylene insert. Twenty-three patients with osteoarthritis of the knee had TKA using a cemented prosthesis (OPTETRAK, Exactech). A cruciate retaining (CR, 10 knees) or a posterior stabilized (PS, 13 knees) implant was randomly assigned at operation. Standard pre- and post-operative antero-posterior and lateral roentgenograms of the knee were taken. Fluoroscopic analysis was performed after at least 18 and 7 months after surgery for the CR and the PS group, respectively. Patients performed stair ascending, chair rising-sitting and step up-down motor tasks. Articular contacts were assumed as the two points on the medial and lateral femoral prosthetic condyles closest to the tibial component base-plate. The spine-cam distance was calculated as the minimum distance between corresponding surfaces. Only small differences in the position of the contacts over knee flexion angles were found among the motor tasks and between the two TKA designs. An overall posterior location of the tibio-femoral contact points was found at the medial and lateral compartments over all motor tasks, a little more pronounced for the PS patients. Statistically significant correlation over the three motor tasks analysed was found between posterior position of the tibio-femoral medial contact in maximum knee flexion and the post-operative tibial posterior slope. This is true for the PS and for the aggregated groups. Although no statistically significant, a general trend is observed of higher degree of flexion at which the cam contacts the spine as the post-operative posterior slopes increases: a 35 higher knee flexion angle for a tibial component implanted with a 5 of posterior slope. Generally, even when the correlations were statistically significant the correlation coefficients were always lower than 0.4. The present work reports combined measurements of post-operative posterior slope and full in-vivo relative motion of the components in both CR and PS TKAs. General trends were found between posterior slope of the tibial component and positions of the tibio-femoral contacts, but a statistically significant correlation was found only for the tibio-femoral medial contact in maximum knee flexion in the PS and in the aggregated. General trends were found between posterior slope of the tibial component and degree of flexion at which the cam starts to be in contact with the spine. The nearly standard antero-posterior translation of the tibio-femoral contacts can be bigger in flatter polyethylene inserts

Introduction. The precise indications for tibial component metal backing and modularity remain controversial in routine primary total knee arthroplasty. This is particularly true in elderly patients where the perceived benefits of metal backing such as load redistribution and the reduction of polyethylene strain may be clinically less relevant. The cost implications for choosing a metal-backed design over an all-polyethylene design may exceed USD500 per primary knee arthroplasty case. Methods. A prospective randomised clinical trial was carried out at the QEII Health Sciences Centre, Halifax, Nova Scotia, to compare modular metal-backed versus an all-polyethylene tibial component. Outcome measures included clinical range of motion, radiographs, survivorship, Knee Society Clinical Rating System, WOMAC and SF-12. Results. 116 patients requesting primary knee arthroplasty were recruited and randomised between the Smith & Nephew Genesis I non-modular (57) and modular (59) tibial designs between September 1995 and August 1997. At 10 years clinical follow-up, 4 implant revisions or intention-to-revise decisions were recorded in the metal-tray/modular group of which 2 were for aseptic tibial component loosening. 2 implant revisions in the all-polyethylene non-modular group were recorded, neither of which were for tibial component loosening. At 5, 7 and 10 year review; the KSCRS, WOMAC and SF12 scores were similar in both groups. As most patients randomised were over seventy years of age, this impacted significantly on the numbers available for longer term review and data was analysed by comparing pre- and post-operative scores for individual patients. Conclusion. There was no difference in performance between the all-polyethylene tibial component and the metal-backed tibial component. The case for using the all-polyethylene tibia in elderly patients is justified on both clinical efficacy and cost-containment grounds

Antibiotic-impregnated cement is frequently used for fixation of total knee prostheses as a measure to prevent postoperative infection. In recent years, more cementless knee prostheses have been implanted especially for younger patients. In 1997 to June 2004, 35044 primary total knee arthroplasties for primary or secondary osteoarthritis were performed in Finland and registered in nationwide arthroplasty register. The patients aged 70 years (range 21–96) on average, and 71.7% were women. During the median follow-up of 39 months (range 0–104), 978 (2.8%) knees were revised. There were 188 (0.58%), 21 (1.09%) and 10 (1.18%) reoperations due to infection after cemented, hybrid and cementless arthroplasties, respectively (p=0.003). In hybrid arthroplasties with cemented tibial component, the septic reoperation rate did not significantly differ from cemented arthroplasties. Instead, the higher number of infections after hybrid arthroplasty was related to use of cementless tibial components (5.3% vs. 0.9%, p< 0.008). In Cox regression model adjusted for age, gender and diagnosis, the hazard ratio for septic reoperation after knee replacement with cementless tibial component was 2.4 (95% CI 1.4–4.1) compared to the cemented alternative. The fixation method did not affect the rate of septic reoperations occurring after the first postoperative year. Cementless fixation of tibial component in primary total knee arthroplasty may associate with an increased risk of early septic reoperation. Until this finding is confirmed in other materials, cementless fixation in primary knee arthroplasty should be used cautiously in patients with increased risk for infection

Unicompartmental knee replacements (UKRs) have inconsistent and variable survivorships reported in the literature. It has been suggested that many are revised for ongoing pain with no other mode of failure identified. Using a medial UKR with an all-polyethylene non-congruent tibial component from 2004–7, we noted a revision rate of 9/98 cases (9.2%) at a mean of 39 months. Subchondral sclerosis was noted under the tibial component in 3/9 revisions with well fixed implants, and the aim of this study was to investigate this as a mode of failure. 89 UKRs in 77 patients were investigated radiographically (at mean 50 months) and with SF-12 and Oxford Knee scores at mean follow up 55 months. Subjectively 23/89 cases (25%) had sclerosis under the tibial component. We describe a method of quantifying this sclerosis as a greyscale ratio (GSR), which was significantly correlated with presence/absence of sclerosis (p<0.001). Significant predictors of elevated GSR (increasing sclerosis) were female sex (p<0.001) and elevated BMI (P=0.010) on both univariate and multivariate analysis. In turn, elevated GSR was significantly associated with poorer improvement in OKS (p<0.05) at the time of final follow up. We hypothesise that this sclerosis results from repetitive microfracture and adaptive remodelling in the proximal tibia due to increased strain. Finite element analysis is required to investigate this further, but we suggest caution should be employed when considering all polyethylene UKR implants in older women and in those with BMI >35

Purpose. The aim of the present study was to look at survivorship and patient satisfaction of a fixed bearing unicompartmental knee arthroplasty with an all-polyethylene tibial component. Materials and Methods. We report the survivorship of 91 fixed bearing unicompartmental arthroplasties with all-polyethylene tibial components (Preservation DePuy UK), which were used for medial compartment osteoarthritis in 79 patients between 2004 and 2007. The satisfaction level of patients who had not undergone revision of the implant was also recorded. For comparison, we reviewed 49 mobile bearing unicompartmental arthroplasties (Oxford UKA Biomet UK Ltd), which had been used in 44 patients between 1998 and 2007. Results. Mean length of follow up of patients with the fixed bearing implant was 44.7 months (range 24 - 74 months) and for the mobile bearing replacement, the mean follow up was 67.6 months (24 - 119). In the fixed bearing design, at maximum follow up period of 74 months, 8 implants (8.8%) had been revised (or were listed for revision) to total knee replacement and in the mobile bearing design over the maximum follow up period of 119 months there had been only one revision (2.0%). Patients who had not undergone revision were asked if they were satisfied with their knee following the unicompartmental arthroplasty. In the fixed bearing design, 83.5% said that they were satisfied with the outcome of the operation compared to 93.9% of the patients receiving the mobile bearing design. Conclusion. We conclude that there is a higher incidence of revision of this fixed bearing design using an all-polyethylene tibial component compared to the mobile bearing design. We found that those patients who had not required revision had a lower rate of satisfaction with the fixed bearing compared to the mobile bearing design

Introduction. For nearly 58% of total knee arthroplasty (TKA) revisions, the reason for revision is exacerbated by component malalignment. Proper TKA component alignment is critical to functional outcomes/device longevity. Several methods exist for orthopedic surgeons to validate their cuts, however, each has its limitations. This study developed/validated an accurate, low-cost, easy to implement first-principles method for calculating 2D (sagittal/frontal plane) tibial tray orientation using a triaxial gyroscope rigidly affixed to the tibial plateau of a simulated leg jig and validated 2D tibial tray orientation in a human cadaveric model. Methods. An initial simulation assessed error in the sagittal/frontal planes associated with all geometric assumptions over a range of positions (±10°, ±10°, and −3°/0°/+3° in the sagittal, frontal, and transverse planes, respectively). Benchtop experiments (total positions - TP, clinically relevant repeated measures - RM, novice user - NU) were completed using a triaxial gyroscope rigidly affixed to and aligned with the tibial tray of the fully adjustable leg-simulation jig. Finally, two human cadaveric experiments were completed. A similar triaxial gyroscope was mounted to the tibial tray of a fresh frozen human cadaver to validate sagittal and frontal plane tibial tray orientation. In cadaveric experiment one, three unique frontal plane shims were utilized to measure changes in frontal plane angle. In cadaveric experiment two, measurements using the proprosed gyroscopic method were compared with computer navigation at a series of positions. For all experiments, one rotation of the leg was completed and gyroscopic data was processed through a custom analysis algorithm. Results. Mathematical simulations showed that over the range of tested orientations, error from our geometric assumptions would be less than 1° and 0.2° in the sagittal and frontal planes, respectively. Results of all bench-top experiments are shown in Figure 1. The average angular error during the TP experiment (black bars) was 1.09°±0.80° and 0.60°±0.46° in the sagittal/frontal planes. The average angular error during the RM experiment (white bars) in the sagittal/frontal planes was 0.27°±0.25° and 0.30°±0.23°. The average angular error from the NU experiment (grey bars) in the sagittal/frontal planes was 1.50°±1.57° and 0.82°±0.77°. During cadaveric experiment one (Figure 2), computed frontal plane angles were 2.83°±0.98°, −1.67°±1.99°, and −4.33°±0.53° after placing distinct 2° lateral, 2° medial, and 4° medial shims. Finally, the average angular error from cadaveric experiment two (Figure 3) over all positions was 1.73°±1.12° and 1.56°±1.45° in the sagittal and frontal planes, respectively. Discussion. Despite the high frequency of TKA procedures, a significant number fail and need to be revised for improper component alignment. This study showed through a first-principles approach that surgeons can assess 2D orientation of the tibial component intraoperatively with 1° of accuracy with a single triaxial gyroscope rigidly affixed to the tibial plateau. Moreover, this study showed through the use of a cadaveric model that surgeons could assess 2D alignment of the tibial component with a gyroscope rigidly affixed to the tibial plateau. To our knowledge, this is first method to offer true 2D tibial tray orientation assessment using only a single triaxial gyroscope

Recent analyses of failure mechanisms continue to show aseptic loosening as the predominant mechanism of total knee arthroplasty (TKA) failure. Evaluation for aseptic loosening begins with careful assessment of plain films radiographs, however the utility of examining lucent lines under a cemented tibial tray remains unclear. The purpose of this study is to examine the distribution of lucent lines under cemented tibial components on single-series anteroposterior (AP) and lateral plain radiographs and to determine their significance in the prediction of aseptic loosening found during revision TKA surgery. Retrospective chart and radiographic review of all patients that underwent revision TKA between 2001–2014 at a single academic hospital center. Revision TKA for periprosthetic fracture, stem fracture, implant dissociation and periprosthetic joint infection were excluded. The most recent pre-revision surgery AP and lateral knee radiographs were assessed by two fellowship trained adult reconstruction surgeons blinded to patient demographics and intraoperative details. Lucent lines under the tibia tray defined as >2mm were documented according to the new KSS radiographic scoring system. Demographic details and the surgeon's assessment whether the tibia tray was loose intraoperatively were extracted from chart review and the operative note, respectively. Univariate and multivariable logistic regression modeling was used to predict the outcome of aseptic loosening. Between 2001 and 2014, 312 revision TKAs were performed that met our inclusion criteria. Of these, 84 (26.9%) had intraoperative loose tibia trays. We observed a significantly increased risk of aseptic tibia loosening among older patients at time of surgery (odds ratio [OR] 1.05, 95% CI 1.02, 1.08). Posterior stabilised primary TKA components conferred a significantly decreased risk of aseptic tibia loosening (OR 0.36, 95% 0.21, 0.60). On an AP radiograph, after adjustment for other zones, the presence of a lucent line in zone 1, 2 or 3 were all significantly associated with tibia loosening, OR 7.35, 8.69 and 22.26 (p<0.0001) respectively. On a lateral radiograph, after adjustment for other zones, the presence of a lucent line in zone 1, 2 or 3 were all significantly associated with tibia loosening, OR 12.89, 18.03, and 11.63 (p<0.004) respectively. The complete absence of lucent lines under a tibia tray on an AP or lateral radiograph were associated with 96% (CI 0.02, 0.07) and 95% (CI 0.02, 0.09) reduced odds of aseptic tibia loosening. Careful examination of lucent lines under a tibia component can be highly predictive of aseptic loosening. The areas associated with highest risk of tibia loosening occur in zone 3 on the AP radiograph (medial or lateral to the keel) and zone 2 on the lateral radiograph (posteriorly). The risk of loosening in the absence of lucent line findings on plain films is significantly low

Aim: The difficulty in accurately assessing coronal alignment of a total knee prosthesis (TKR) is widely accepted in the literature yet standard practice in the UK is to obtain AP and lateral knee views only; we compared standard AP knee films with long leg views of TKR in order to determine the most optimal way of assessment of the prosthetic knee alignment. Methods: We included all patients who underwent TKR between January and September 2005 at Kings College Hospital under the care of one orthopaedic consultant. We excluded 11 patients with revision surgery, augmented prosthesis, high tibial osteotomies or severe tibiotalar joint arthritis. We included 50 sets of radiographs from 48 patients (17 men and 31 women). The prostheses used were PFC (40) and Scorpio (10) and six of them were navigated and 44 were standard TKR. We compared the difference between the angle of the tibial component with the mechanical axis of the tibia in the long leg image and the angle of the prosthesis with the midline of the visualised tibia in a standard antero-posterior knee view. Statistical analysis was carried out using the student t-test. Results: The mean difference between the two views was 5.34o (range 1.9o – 12o) (p< 0.001). We did not find any difference between the Scorpio and PFC knees or between navigated and non navigated prostheses. Conclusion:We concluded that the long leg views compared with the standard antero-posterior knee views provide more accurate information on the position and alignment of the tibial component of a TKR

In a single-blind, randomised series of knee replacements in 116 patients, we used radiostereometric analysis (RSA) to measure micromotion in three types of tibial implant fixation for two years after knee replacement. We compared hydroxyapatite-augmented porous coating, porous coating, and cemented fixation of the same design of tibial component. At one to two years, porous-coated implants migrated at a statistically significantly higher rate than hydroxyapatite-augmented or cemented implants. There was no significant difference between hydroxyapatite-coated and cemented implants. We conclude that hydroxyapatite augmentation may offer a clinically relevant advantage over a simple porous coating for tibial component fixation, but is no better than cemented fixation

Introduction Cemented fixation of the tibial component is the standard treatment for patients older than 65 with long-standing excellent results. Whether cemented fixation is best even for younger patients is still debated, and if uncemented fixation is chosen, the question remains as to whether screws are necessary as an adjunct. We present the results of a prospective randomized study comparing cemented and two modes of uncemented fixation. Methods Thirty-five patients (mean age 56 years, range 29 to 64) were operated with the Profix (Smith& Nephew) TKA for gonarthrosis grade III to V. At the operation, the patients were randomly allocated to fixation of the tibial component with cement (Group C, n=6), uncemented fixation with hydroxyapatite (HA) coating without screws (Group HA, n=14), or uncemented fixation with HA coating and with screws (Group HA+, n=15). The implants and tibiae were prepared for RSA with tantalum markers. RSA was performed post-operatively, three, 12 and 24 months post-op. Results There were no complications or revisions during the follow-up. For all three types of fixation the migration was larger during the initial three months, after which the migration leveled off. At three months, subsidence and tilting of the implant was significantly larger for group HA- compared to group C (P = 0.009 − 0.036), with the migration for group HA+ in between. This difference between the groups persisted up to 24 months. When examining the migration from three to 24 months, the implants in all three groups displayed very small migration, magnitudes well below the detection limit of RSA. There were no differences in magnitude of migration between the three groups between three and 24 months. Conclusions The uncemented tibial component displays relatively large migration within the first three months compared to the cemented implant, and uncemented fixation without screws has larger migration than when screws are used. This larger initial migration for the uncemented fixation probably is due to “setting-in” of the prostheses. However, if the uncemented implant “survives” this early period, the results of the present study indicate a good long term prognosis, even when no screws are used for additional stability. This is important, since osteolysis frequently has been observed in relation to screws in the proximal tibia. One reason for the stable fixation of the uncemented implants may be the use of HA-coating. In relation to the conduct of this study, one or more of the authors is in receipt of a research grant from a non-commercial source

Introduction Mobile-bearing total ankle arthroplasty has gained more interest in recent years. Clinical results show favourable but varying results, with survival rates between 70% and 90% at 10-year follow-up. Design-specific differences in early migration patterns might explain differences in result and possible modes of failure. Methods Prospective study of a cementless mobile-bearing total ankle arthroplasty by radiostereometric analysis (RSA). Fifteen total ankle arthroplasties were performed in patients with rheumatoid arthritis. The American Orthopaedic Foot and Ankle Society ankle score and radiostereometric radiographs were evaluated at regular intervals throughout the follow-up period: immediately postoperatively, 6 weeks postoperatively, 3 months, 6 months, and 12 months postoperatively and yearly thereafter. Results The postoperative clinical results improved. We observed increased migration of the tibial component during the first 3 months, but this stabilized by the 6-months followup. The mean lateral-medial migration was 0.8 mm, distal-proximal migration was 0.9 mm, and posteroanterior migration was −0.5 mm. The latter implicated that the total resultant migration was in anterior and valgus tilting of this tibial component. This resulted in a main mode of migration proximal, anterior and valgus tilting of the tibial component. Discussion This pilot study showed initial migration of this mobile-bearing ankle prosthesis into upward anterior and valgus tilting. However, migration stabilized at 6 months postoperatively. We think the surgical technique (anterior cortical window for placement) and the method of tibial fixation likely explain this migration

Introduction We report the early results of a series of 80 primary total knee replacements (TKRs) using a trabecular metal tibial component (TMT). Methods Significant tibial bone loss and scarcity of kit were the only reasons for patients not receiving a TMT. Age, sex, diagnosis and body mass index (BMI) were recorded. Patients were scored pre-operatively using the Oxford Knee and SF-12 scores. These were repeated at subsequent clinical follow up where standard X-rays were also taken. Range of movement was estimated using a goniometer and stability assessed clinically. This regimen was identical to that in place for the standard knee previously used by the senior author with a cemented tibial component and this group is used in comparison as possible. Results To date there are 80 TMT knees in the series with 36 standard cemented TKRs in comparison. The mean age of the whole series is 70 years (20–90) with no difference between the groups. Sixty five per cent of the series were female. All bar three patients had osteoarthritis. The mean BMI was 30.3 (20.9–46.2). The mean pre-op Oxford score was 45.8 in the TMT group and 44.5 in the cemented group. At a mean follow up of 13.3 (9–17) months in the TMT group and 18.7 (9–19) months in the cemented group this fell to 22.5 and 20.5 respectively. The physical component of the SF-12 score improved from 27.3 to 40.7 in the TMT group and from 27.5 to 45.5 in the cemented group. There was no statistical difference between the groups using either score. The mean amount of flexion pre-operatively was 106 (65–135) degrees for the series. This was maintained postoperatively at 105 degrees (70–125) with no difference between the groups. There was one deep infection in the cemented group that underwent revision and one non-fatal pulmonary embolus in the cemented group. There were no worrying radiological signs in either group. Conclusion Trabecular metal is made from elemental tantalum. The TMT is an uncemented component with a truly porous structure for bone ingrowth and a modulus of elasticity equivalent to bone that allows physiological transfer of stresses. The early clinical and radiological results are equal to a cemented prosthesis. Further follow up is required to see whether this is maintained over time

Background: Correct rotational alignment of the femoral and tibial component is an important factor for successful TKA. The transepicondylar axis is widely accepted as a reference for the femoral component. There is no such reference for the tibial component. CT scans were used in this study to measure which tibial landmark most reliably reproduces a correct femoro-tibial rotational alignment in TKA. Furthermore, the impact of computer-assisted navigation on rotational alignment is investigated. Materials and Methods: After informed consent, 80 patients were randomized to receive either navigated or conventional TKA. All patients received a cemented, unconstrained, cruciate-retaining TKA with a rotating platform. CT scans were performed 5–7 days postoperatively but before discharge. The rotational variance between the femoral and tibial components was measured. Results: There was notable rotational variance between the femoral and tibial components in both groups. In the navigated group, the median variance was 1.2° relative external rotation of the femur (range: 16.2° relative external to 12.7° relative internal rotation of the femur). In the conventional group, the median variance was 1.7° relative internal rotation of the femur (range: 9.0° relative external to 14.4° relative internal rotation of the femur). Using the medial third of the tuberosity as reference for tibial rotational alignment, 67.5% of all TKA had a femoro-tibial variance within ± 5°, 85% within ± 10° and 97.5% within ± 20°. Using the medial border of the tibial tubercle as reference this variance was greater, 3.8% had a femoro-tibial variance within ± 5°, 15% within ± 10° and 68.8% within ± 20°. Conclusion: Using fixed bone landmarks for rotational alignment leads to a notable variance between femoral and tibial component. Computer-assisted navigation did not reduce this variance. Referencing the tibial rotation on a line from the lateral border of the medial third of the tibial tubercle to the center of the tibial tray resulted in a better femoro-tibial alignment than using the medial border of tibial tubercle as landmark. Surgeons using fixed bearings with a high conformity between the inlay and the femoral component should be aware of this effect to avoid premature polyethylene wear

Radiolucent lines at the bone-cement interface beneath the tibial components were assessed in 91 consecutive Oxford meniscal knee replacements in 78 patients. Of 80 knees in which radio-opaque cement was used, a radiolucent line was observed in 77, with a radiodense line in the bone immediately adjoining. Radiolucent lines developed in the majority of patients within one year after operation. In 11 knees fixed with radiolucent cement (which precluded assessment of the radiolucent line) a radiodense line was observed beneath the lucent cement in all cases. Histological examination of the interface obtained from secure tibial components showed the lucent zone to be composed of fibrocartilaginous connective tissue and the radiodense line to be a thick lamella of bone. It is suggested that the living bone under a rigid prosthesis requires a layer of relatively compliant fibrocartilaginous material at its interface to accommodate load-bearing. Attention is drawn to the importance of the radiodense line: its presence may constitute positive evidence that healing at the level of bone section is complete and that equilibrium is established; its absence at a mature interface may indicate disequilibrium and impending failure

INTRODUCTION. Balancing accurate rotational alignment, minimal overhang, and good coverage during total knee arthroplasty (TKA) often leads to compromises in tibial component fit, especially in smaller-sized Asian knees. This study compared the fit and surgical compromise between contemporary anatomic and non-anatomic tibial designs in Japanese patients. METHODS. Size and shape of six contemporary tibial component designs (A:anatomic, B:asymmetric, C-F:symmetric) were compared against morphological characteristics measured from 120 Japanese tibiae resected following TKA surgical technique. The designs were then digitally placed on the resected tibiae. Each placement selected the largest possible component size, while ensuring <1mm overhang and proper alignment (within 5° of neutral rotational axis). When a compromise on either alignment or overhang was required (due to smaller-sized component unavailable), the design was flagged as “no suitable component fit” for that bone. Tibial coverage was compared across designs. Next, 32 femora were randomly selected from the dataset onto which each design was evaluated in two placements, the first maximizing coverage without attention to rotation and the second enforcing rotational accuracy. Downsizing was identified if in the second placement, enforcing rotational accuracy, required a smaller component size compared the first placement. The degree of mal-alignment while maximizing coverage, the incidence of downsizing, and difference in coverage between the two placements were compared across designs. Statistical significance was defined at p<0.05. RESULTS. Design A closely matched the tibial morphology and had better size and shape conformity than Designs B-F (select metrics shown in Fig. 1). Design A exhibited higher average coverage (92%) than other designs in all ethnicities (85–87%, Fig. 2A) (p<0.01). Designs D-F had no suitable component fit in 1.6–2.4% of the bones (Fig. 2B). Coverage generally decreased with reduced component size (Fig.2C), with Design A having higher coverage than Designs B-F across all sizes. In the randomly selected 32 tibiae, enforcing rotational accuracy significantly compromises coverage in Designs B-F (Fig.3A) (p<0.01), with up to 15% in individual bones. In contrast, coverage of Design A was not influenced by enforcing rotational accuracy (p=0.52). Designs B-F were found to require downsizing on 41–66% of bones due to >5° rotation, with components internally rotated beyond 10° on 31–59% of the bones (Fig.3B). In contrast, Design A required downsizing on only 6% of the bones, caused by small mal-rotations (<10°). Designs B-D and F required downsizing of ≥2 sizes on 3–16% of bones; while a single downsize was sufficient for Design A (Fig.3C). DISCUSSION. The anatomic design not only has the closest match to the natural tibia, but also consistently has the highest coverage across bone sizes. It also exhibits fewer incidences of downsizing and reduced propensity for mal-alignment than the non-anatomic designs investigated. In contrast, in the non-anatomic tibial component designs, ensuring rotation accuracy considerably compromised tibial coverage. This result, suggests that many non-anatomic designs do not fully accommodate variations in bone anatomy in the Japanese patients, thus forcing a compromise

Background and Purpose:. Modularity of the tibial component in total knee arthroplasties (TKA) has many surgical benefits. It also reduces inventory related expenses but increases implant cost. The resulting locking mechanism micromotion that leads to non-articular microwear and has been an accepted consequence of modularity. The purpose of this study is to evaluate the risk of revision (all-cause and aseptic) of a monoblock all-polyethylene tibial component compared to a fixed bearing modular tibial construct with the same articular geometry while adjusting for potential confounders in a community based sample of primary TKAs. In addition, younger and older patient specific risk of revision was evaluated. Method:. A retrospective analysis of prospectively collected data from a Total Joint Replacement Registry (TJRR) was conducted. All 27,657 primary TKAs enrolled between 2001 and 2010 performed for any diagnosis with the same implant from a single manufacturer were included in the study. Patient characteristics, as well as surgeon, hospital, procedure, and implant characteristics were compared by the main exposure of interest, i.e. the type of tibial prosthesis (monoblock all-polyethylene vs. metal-backed modular). The main endpoints of the study were all-cause and aseptic revisions only. Descriptive statistics and Cox-regression models were employed. Hazard ratios (HR) and 95% confidence intervals (CI) are provided. Results:. The cohort consisted of 2,306 (8.3%) monoblock all-polyethylene tibial component TKAs and 25,351 (91.7%) modular metal-backed components. No gender, diagnosis or diabetic status differences were noted between the monoblock and modular cohorts. Patients with monoblock tibias were older (71.8 vs. 68.1 yrs, p < 0.001) and had a lower body mass index (30.1 vs. 31.6 kg/m2, p < 0.001). The median follow up time of the cohort was 2.9 years (interquartile range 1.2–5.1 years), during which 22 (0.95%) monoblock arthroplasties and 550 (2.17%) modular arthroplasties were revised. The all-cause revision rate/100 years of follow-up for monoblock and modular cohorts was 0.30 and 0.65, respectively. Their aseptic revision rate/100 of follow-up was 0.18 and 0.35, respectively. In adjusted overall models, the risk of all-cause revision (HR = 0.51, 95% CI 0.33–0.78, p = 0.002) and aseptic revision (HR = 0.59, 95% CI 0.29–1.19, p = 0.139) was lower in the monoblock cohort compared to the modular cohort. In adjusted models of patients 65 years and older, the risk of all-cause revision is 0.59 (95% CI 0.35–0.99, p = 0.045) in the monoblock cohort compared to modular cohort. In adjusted models of patients younger than 65 years old, the risk of all-cause revision (HR = 0.26, 95% CI 0.10–0.72, p = 0.010) and aseptic revision (HR = 0.27, 95% CI 0.11–0.65, p = 0.003) were lower in the monoblock compared to the modular cohort. Conclusion:. For our entire cohort of 27,567 primary fixed bearing TKAs, monoblock all-polyethylene tibial components had a 49% lower risk of revision for all-causes and a 41% lower risk of aseptic revision when compared to modular metal-backed tibial constructs. For patients younger than 65 years old, the all-polyethylene component had a 74% lower risk of all-cause revision and a 73% lower risk of aseptic revisions when compared to modular tibial constructs

In the anatomical studies for Caucasian, it has been reported that the center of plateau tends to be located central or lateral from the tibial canal axis. However, in the three dimensional analysis of author, the center of plateau was located on average 4.4 mm medial from the point of tibial canal axis passing through the plateau. The purpose of this study is to examine the placement of the tibial component in relation to the anatomical axis of the tibia in total knee arthroplasties for Korean patients and to identify this mismatch affecting the measurement of postoperative mechanical axis. Measurements were performed on the pre- and postoperative radiographs of 60 osteoarthritic knees with varus deformity replaced between October 2005 and May 2008 using PFC. The inclusion criteria was the cases with the accurate coronal alignment of component, in which α angle ranged from 94 to 96° and β angle ranged from 89 to 91°. The mean age was 66.6 years (range, 54 to 79), and the body mass index was 27.0 kg/m2 (range, 20.7 to 37.7). Radiological measurements were performed using an orthoreontgenogram. Preoperatively, 30 patients with varus deformity lesser than vaurs 10° were classified to group A and 30 patients greater than vaurs 10° were classified to group B. Post-operatively, the distance between the midline of the tibial stem and anatomical axis (medial offset) was measured at the level of tibial resection. These distances were compared between the group A and B. The postoperative mechanical axes were compared between the group A and B. The intra- and inter-observer reliabilities were assessed. In this study, intraclass correlation coefficient values of all measurements were greater than 0.8. The mean preoperative mechanical axes were varus 7.4±2.3° in group A and varus 16.9±4.0° in group B (p=0.000). The mean medial offsets were 2.5±1.9mm (range, −3.6 to 5.9) in group A and 3.9±2.7mm (range, −1.1 to 10.2) in group B (p=0.021). The tibial stems were located medial to anatomical axis in 22 knees (73.3%) of group A and 26 knees (86.7%) of group B. The mean postoperative mechanical axis were varus 1.3± 1.2° (range, varus 3.6 to valugs 1.6°) in group A and varus 2.5± 2.0° (range, varus 5.9 to valugs 2.1°) in group B (p=0.004). In this study of TKA, the tibial component in relation to anatomical axis tends to be located medial. The postoperative mechanical axis remained more varus in spite of the accurate coronal alignment of the component as the preoperative varus deformity was more severe. This study suggests that the radiographic measurement of postoperative mechanical axis using a line passing the component center has the limitation

Introduction. Malpositioning of the tibial component is a common error in TKR. In theory, placement of the tibial tray could be improved by optimization of its design to more closely match anatomic features of the proximal tibia with the motion axis of the knee joint. However, the inherent variability of tibial anatomy and the size increments required for a non-custom implant system may lead to minimal benefit, despite the increased cost and size of inventory. This study was undertaken to test the hypotheses: . 1. That correct placement of the tibial component is influenced by the design of the implant. 2. The operative experience of the surgeon influences the likelihood of correct placement of contemporary designs of tibial trays. Materials and Methods. CAD models were generated of all sizes of 7 widely used designs of tibial trays, including symmetric (4) and asymmetric (3) designs. Solid models of 10 tibias were selected from a large anatomic collection and verified to ensure that they encompassed the anatomic range of shapes and sizes of Caucasian tibias. Each computer model was resected perpendicular to the canal axis with a posterior slope of 5 degrees at a depth of 5 mm distal to the medial plateau. Fifteen joint surgeons and fourteen experienced trainees individually determined the ideal size and placement of each tray on each resected tibia, corresponding to a total of 2030 implantations. For each implantation we calculated: (i) the rotational alignment of the tray; (ii) its coverage of the resected bony surface, and (iii) the extent of any overhang of the tray beyond the cortical boundary. Differences in the parameters defining the implantations of the surgeons and trainees were evaluated statistically. Results. On average, the tibial tray was placed in 5.5 ± 3.1° of external rotation. The overall incidence of internal rotation was only 4.8%: 10.5% of trainee cases vs. 0.7% of surgeon cases (p < 0.0001). The incidence of internal rotation varied significantly with implant design, ranging from 1.7% to 6.2%. Bony coverage averaged 76.0 ± 4.5%, and was less than 70% in 8.6% of cases. Tibial coverage also varied significantly between designs (73.2 ± 4.3% to 79.2 ± 3.8%; p < .0001). Clinically significant cortical overhang (>1 mm), primarily in the posterior-lateral region, was present in 12.1% of cases, and varied by design, as expressed by the area of the tray overhanging the cortical boundary (min: 2.3 ± 6.7 mm. 2. ; max: 4.7 ± 7.9 mm. 2. ; p < .0001). The surgeons and the trainees also differed in terms of the incidence of sub-optimal tibial coverage (10.0% vs. 14.4%, p < 0.001), and cortical overhang (7.4% vs. 9.7%, p < 0.001). Discussion. 1. Malrotation, bony coverage and cortical overhang are all strongly influenced by the design of the tibial tray selected and the experience of the surgeon. 2. Compared to trainees, experienced surgeons tend to position tibial trays in more external rotation, and with less concern for reduced bony coverage and cortical overhang than trainees. 3. This study supports the hypothesis that improvements in the outcome and reliability of TKR may be achieved through attention to implant design

Aims: To prospectively study the optimum fixation of the tibial component in patients younger than 65 years, where the mode of fixation is randomized. Methods: 35 patients (mean age 56 years, range 29 to 64) were operated with the Profix (Smith& Nephew) TKA due to gonarthrosis grade III to V. The patients were randomly allocated to fixation of the tibial component with cement (Group C) (n=6), uncemented fixation with hydroxyapatite coating (HA) without screws (Group HA−) (n=14), or uncemented fixation with HA coating and with screws (Group HA+) (n=15). Radiostereometry (RSA) was performed postop., 3, 12 and 24 months postop. Results: There were no complications or revisions during the follow-up. Up to 3 months the cemented implants migrated the least and the HA- group the most (P = 0.009 – 0.036). From 3 to 24 months however, the implants in all three groups displayed very small migration, magnitudes well below the detection limit of RSA, and there were no differences between the three groups. Conclusions: The uncemented tibial component displays relatively large migration within the first 3 months compared to the cemented implant, and uncemented fixation without screws have larger migration than when screws are used. This larger initial migration for the uncemented fixation probably is due to “setting-in” of the prostheses. However, if the uncemented HA-coated implant “survives” this early period, the results of the present study indicate a good long term prognosis, even in designs where no screws are used for additional stability

There is a report that higher failure rate in uncemented total knee replacement components due to loosening. However, uncemented fixation has been an attractive concept because of bone preservation and revision surgery, potential improved load transfer, and decreased surgical time. “Regenerex” is a porous titanium layer with excellent initial fixation, and the promise of providing favourable biological fixation. This is used with the Biomet Vanguard total knee replacement. 14 patients had undergone total knee replacement surgery comprising 11 men and three women with an average age of 63.07 years, and a body mass index of 30.33. Three of these patients required revision, because of tibial component loosening within 12 months of surgery. There were two men and one woman with an average age of 63.33 and BMI of 34.55. Clinically, patients developed pain and a gradual deformity as a result of a symmetrical collapse of the proximal tibial bony support surface. Histopathology on the removed specimens shows the development of fibre cartilaginous metaplasia with evidence of necrotic bone. This was similar in all patients. There was no foreign body giant cell reaction, and no evidence of infection. The appearance was suggested of osteonecrosis, occurring gradually. The incidence of frequency of this complication with this component in our experience is of concern, and the aim of this presentation is to determine whether this is a more widespread phenomenon

We report a prospective study of gait and tibial component migration in 45 patients with osteoarthritis treated by total knee arthroplasty (TKA). Migration was measured over two years using roentgen stereophotogrammetry. We used the previously established threshold of 200 μm migration in the second postoperative year to distinguish two groups: a risk group of 15 patients and a stable group of 28 patients. We performed gait analysis before operation and at six months and at two years after TKA. On all three occasions we found significant differences between the two groups in the mean sagittal plane moments of the knee joint. The risk group walked with higher peak flexion moments than the stable group. The two groups were not discriminated by any clinical or radiological criteria or other gait characteristics. The relationship which we have found between gait with increased flexion moments and risk of tibial component loosening warrants further study as regards the aetiology of prosthetic loosening and possible methods of influencing its incidence

We examined the placement of the stem in relation to the medial tibial cortex when using total knee replacements (TKRs) with medially-offset tibial stems in Korean patients. Measurements were performed on the pre- and post-operative radiographs of 246 osteoarthritic knees replaced between January 2005 and May 2006 using the Genesis II or E-motion TKR with a medially-offset stem. Pre-operatively, we measured the distance between the mechanical axis and that of the tibial shaft and post-operatively, that between the midline of the tibial stem and the axis of the shaft. Knees were identified in which there was radiological contact between the tip of the stem and the medial tibial cortex. The mechanical axis was located medial to the axis of the shaft in 203 knees (82.5%). Post-operatively, the midline of the tibial stem was located medial to the tibial shaft axis in 196 knees (79.7%). In 16 knees (6.5%) there was radiological contact between the tibial stem or cement mantle and the medial tibial cortex. Our study has shown that the medially-offset stem in the tibial component may not be a good option for knees undergoing replacement for advanced osteoarthritis in some Korean patients

Cadaveric knees replaced with the Geomedic, ICLH, Marmor and Total Condylar prostheses were tested in axial compression, in rotation and in hyperextension in order to observe the strength of fixation of the tibial components. In axial compression the strengths at failure varied widely, both with any one prosthesis and between prostheses. This is attributed largely to the strength of the cancellous bone of the tibia, which was measured in each case and also varied widely. Three natural knees failed at loads of 7300, 7600 and 8300 newtons respectively, whereas the strengths of replaced knees ranged from 3000 to 15750 newtons. At least one example of each design failed at less than 7300 newtons, suggesting little or no reserve of strength. The strength of fixation was greater when the tibial prosthesis was large enough to rest on the whole cross-section of the tibia. In rotation the three prostheses embodying rollers in troughs were stiffer than the Marmor which had a nearly flat tibial-bearing surface. The presence or absence of the cruciate ligaments had a negligible effect on torsional stiffness. In hyperextension, knees replaced with the ICLH, Marmor and Total Condylar prostheses failed by rupture of the posterior capsule at moments of about 60 newton-metres, compared with about 100 for natural knees. With the Marmor prosthesis the anterior cruciate ligament was avulsed at about 20 newton-metres compared with about 75 in natural knees, suggesting that in this respect the retention of the cruciate ligaments contributes little. None of the four knees tested after inserting a Geomedic prosthesis showed strengths as high as those replaced with the other three designs

The purpose of this study is to evaluate accuracy of tibia cutting and tibia implantation in UKA which used navigation system for tibia cutting and tibia component implantation, and to evaluate clinical results. We performed 72 UKAs using navigation system from November, 2012. This study of 72 knees included 56 females and 16 males with an average operation age of 74.2 years and an average body mass index (BMI) of 24.8 kg/m2. The diagnosis was osteoarthritis (OA) in 67 knees and osteonecrosis (ON) in 5 knees. The UKA (Oxford partial knee microplasty, Biomet, Warsaw, IN) was used all cases. We evaluated patients clinically using the Japanese orthopaedic association (JOA) score, range of motion (ROM), operation time, the amount of bleeding and complications. Patients were evaluated clinically at preoperation and final follow up in JOA score and ROM. As an radiologic examination, we evaluated preoperative and postoperative lower limb alignment in FTA (femoro-tibial angle) by weightbearing long leg antero-posterior alignment view X-rays. Also we evaluated a tibial component implantation angle by postoperative CT, and tibia cutting angle by intraoperative navigation system. We defined the tibial angle which a tibia functional axis and the tibia component made in coronal plane, also tibial posterior slope angle which a tibia axis and tibia component made in sagittal plane by CT. We measured tibial angle and tibial posterior slope angle by 3D template system. We performed UKA in all cases mini-midvastus approach. At first we performed osteotomy of the proximal medial tibia using CT-Free navigation. At this procedure we performed osteotomy to do re-cut if check did cutting surface in navigation, and there was cutting error (>3°), and then to do check again in navigation. Next we did not use navigation and went the osteotomy of the distal femur with an IM rod and drill guide of microplasty system. And then we performed a trial and decided bearing gap and moved to cementing. At first we went cementing of the tibia component. At this procedure we went to drive implant again if check did implant surface in navigation, and there was implantation error(>3°), and to do check. We checked did tibia cutting, tibia implantation carefully in navigation. In addition, We sterilize a clips and use it came to be in this way possible for the check of the first osteotomy side exactly. ROM was an average of 122.7° of preoperation became an average of 128.2° at final follow up, and JOA score was an average of 50.5 points of preoperation improved an average of 86.6 points at final follow up after UKA. An average of the operation time was 94 minutes, an average of the amount of bleeding was 137.7ml, and complications were one proximal type deep venous thrombosis (DVT) and one pin splinter joining pain by navigation, .Asetic loosening(tibial component) was one case, and this conversed the TKA. In the radiologic evaluation, FTA was an average of 182.1° of preoperation corrected an average of 175.9°after UKA. In other words, an average of 6.2° were corrected by UKA. The tibia component implantation angle was an average of 90.18° in a measurement by the CT after UKA, intoraoperative tibia component implantation angle was an average of 90.32° in a measurement by the navigation system. These two differences did not accept the significant difference at an average of 1.33°.(P=0.5581). Similarly, the posterior slope angle were as follow; average of 5.65°by CT and average of 5.75°by navigation. These two differences did not accept the significant difference at an average of 1.33°. (P=0.6475). Discussion: We performed UKA using navigation and evaluated the implantation accuracy for tibia osteotomy, tibia implantation. They were good alignment with an average of 90.18°, and outliers more than 3° were two cases(2.8%). It will be necessary to examine long-term progress including clinical results complications in future. We are performed UKA now in femur side using PSI(patient specific instruments) and tbia side using Navigation

BACKGROUND. Some papers recently reported conflicting results on implant survivorship in all-poly tibial UKRs. Furthermore, the influence of BMI on this specific implant survivorship remains unclear, since existing reports are often based on small series of non-consecutive patients with different follow up durations, enabling to generate meaningful conclusions. PURPOSE. To determine the 10-years survival rate of an all-poly tibial UKR in a large series of consecutive patients and to investigate whether a correlation exists between a higher BMI and an increased risk of revision for any reason. METHODS. A retrospective evaluation of 273 patients at 6 to 13 years of follow-up was performed. Clinical evaluation was based on KSS and WOMAC scores. Subjective evaluation was based on a VAS for pain self-assessment. Radiographic evaluation was performed by 3 independent observers. A Kaplan-Meier survival analysis was performed assuming revision for any reason as primary endpoint. Reason of revision was determined basing on clinical and radiographic data. RESULTS. The 10-years implant survivorship was 90.8%. Twenty-five revisions (9.2%) were performed and aseptic loosening of the tibial component was the most common failure mode (11 cases, 4%). No significant correlation was identified between failure and patients'BMI. Mean post-operative results for KSS and WOMAC score were 87.0 (st.dev. 14.6) and 87.37 (st.dev. 11.48), respectively. VAS showed a significant improvement (p<0.0001) respect to pre-operative condition. CONCLUSIONS. Unlike some recent reports, this study demonstrated a satisfactory 10-years implant survivorship using an all-poly tibial UKR. A higher BMI does not reduce survival rate at 6 to 13 years of follow-up

Aim. To undertake a biomechanical study to determine the existence of any difference in the early tibial component fixation to bone, between two widely used techniques of cementation, which may confer an influence on implant survival. Method. 20 tibial saw bones were prepared by standard methods using extramedullary instrumentation to receive a fixed bearingtibial component (PFC, DePuy). Under controlled laboratory conditions, thetibial trayswere implanted with CMW cement using either of the two following cementation techniques (10 implants in each group): Full cementation–application of cement to the undersurface of the tibial tray, the keel, the cut surface of the tibia and its stem hole. Surface cementation – application of cement only to the undersurface of thetibial tray and the cut surface of the tibia. 72 hours after implantation, the fixation of the cemented components was assessed by determining the load to failure under controlled tensile stresses (using an Instron Electro-mechanical tensile tester). Results. The data suggested a two-stage process to failure with an initial de-bonding load preceding a peak load before failure. Highly significant differences between the two techniques were observed. The mean initial de-bond load for fully cemented implants was 1115N, compared to 590N for the surface cemented group (p<0.00005). The mean peak load before failure was also significantly greater in the fully cemented group (1830N vs 1370N, p<0.001). Conclusion. Full cementation of the tibial component in total knee arthroplasty confers greater initial fixation to bone than surface cementation and may therefore positively influence implant longevity

The 4th England and Wales NJR showed that 83% of total knee replacements were cemented (47,626 knees). This study aimed to compare modern techniques of cementation of the proximal tibia in an experimental model against tourniquet-less knee replacement surgery with cancellous bone suction and a cement gun. A metal box was constructed to approximate the proximal tibia and open cell sawbone simulated the tibia with simulated blood flow and bone suction. Each sample was prepared in an identical fashion except for the cementing technique. The techniques compared were of. Tourniquet,. No tourniquet,. No tourniquet + cancellous bone suction and. No Tourniquet, suction applied + cement gun pressurisation. Samples were subsequently sectioned, polished and the cemented area measured using a planimeter. ANOVA testing demonstrated that the techniques were significantly different (p< 0.0001). Bonferroni Comparison demonstrated that the Exeter technique gave significantly better cement penetration for central and lateral measurements (p< 0.0001 and p< 0.0001) compared to all other methods. The authors believe that our technique of cementation of the proximal tibia offers an easy and reproducible way of getting good quality cementing of the tibial component in total knee replacement and this is borne out by our experimental model

To assess migration of the tibial component we used roentgen stereophotogrammetric analysis in 40 patients who had had a total knee arthroplasty after failure of a closing wedge osteotomy and compared them with 40 matched patients after primary total knee arthroplasty. We found no difference in migration over time or in the tendency for continuous migration between the two groups. There were no differences in alignment or position of the knee prosthesis or in the clinical outcome. Our findings show that revision of a failed high tibial osteotomy to a total knee arthroplasty is effective

The evaluation of two methods for the placement of the tibial component of total knee arthroplasties in obese patients. Between December 2004 and October 2008 we studied 38 obese patients who underwent cemented total knee arthroplasty (using the rotating platform tibial tray) due to medial compartment osteoarthritis and consequent varus deformity. All patients had a body mass index (BMI)> 40. Functional outcome was assessed using the Knee Society Score (KSS). The study was based on the comparison between extramedullary (group A) and intramedullary (group B) instrumentation systems for the placement of the tibial prosthesis. The main endpoint was the immediate post-operative knee joint alignment. There were 10 male and 28 female patients. The average follow-up period was 13.8 months (minimum follow-up of 6 months). There were 22 patients in group A whereas 16 patients comprised group B. In 5 of the 22 patients in group A there was an average varus malalignment of 40 and a mean KSS of 71.5 at the time of the latest follow-up visit. In the rest of patients of both groups there was a valgus alignment between 0 and 70 and a mean KSS of 86.4 respectively. Our experience suggests that the intramedullary instrumentation technique for the placement of the tibial component offers a more favourable post-operative alignment as well as better functional outcome in obese patients

Purpose. Unicompartmental knee replacement (UKR) is an established, bone preserving surgical treatment option for medial compartment osteoarthritis (OA). Early revision rates appear consistently higher than those of total knee replacement (TKR) in many case series and consistently in national registry data. Failure with progression of OA in the lateral compartment has been attributed, in part, to surgical technical errors. In this study we used navigation assisted surgery to investigate the effects of improper sizing of the mobile bearing and malrotation of the tibial component on alignment and lateral compartment loading. Method. A total of eight fresh frozen cadaveric lower limbs were used in the study. After thawing overnight, a Brainlab navigation system with an Oxford (Biomet, Inc) medial UKR module was used to capture the native knee anatomy and alignment using a digitizing probe. Following registration, the case was performed with navigation verified neutral cuts and an ideal insert size was selected to serve as a baseline. The bearing thickness was subsequently increased by 2 mm increments to simulate progressive medial joint overstuffing. Excessive tibial internal rotation of 12 was also simulated at each of the intervals. Knee alignment in varus or valgus was recorded in real time for each surgical scenario with the knee in full extension and at 20 of flexion. Lateral compartment peak pressure was measured using a Tekscan pressure map. Results. Incremental overstuffing of the medial compartment with inserts of increasing thickness resulted in a progressive shift to more valgus knee alignment. Internally rotated sagittal cuts at 12 resulted in a further valgus shift for a given insert size. The valgus shift was detectable at full extension however it was more pronounced at 20 of flexion. Conclusion. The intentional technical errors of overstuffing and malrotation in UKR produced coronal valgus knee alignment and a greater load shift to the lateral compartment. These errors can be construed to contribute to the higher early failure rates associated with UKR when compared to TKR. Special care should be taken to ensure a neutral sagittal tibia cut and appropriate bearing selection. The Intra operative verification of knee alignment should be conducted at 20 of flexion where such errors will be easier for the surgeon to detect and rectify

Purpose:. Management of unicompartmental knee osteoarthritis (OA) in middle-aged patients is a challenging problem. Recent studies have underlined the efficacy of UKA not just in elderly, but also in middle-aged patients. The primary purpose of the present study was to determine the short to mid-term survivorship of an all-poly tibial UKA in patients under 60 years of age. The secondary purpose was to prospectively evaluate the clinical outcome in this selected group of patients. METHODS:. Thirty-three consecutive patients under 60 years of age at the time of surgery with isolated medial compartment OA underwent a unilateral medial UKA from 2002 to 2005 and were prospectively followed. A Kaplan-Meyer analysis was performed to determine the 8-years implant survivorship with revision for any reason as endpoint. KSS, WOMAC, Tegner-Lysholm, Tegner and VAS scores were prospectively evaluated at 3 to 6 years follow-up. Weight-bearing radiographs were collected pre-operatively and at 3 to 6 years follow-up to prospectively evaluate femorotibial angle (FTA), tibial plateau angle (TPA) and posterior tibial slope (PTS). RESULTS:. The 8-years Kaplan-Meier survivorship with revision for any reason as endpoint was 83%. Five failures were reported and in 3 patients aseptic loosening of the tibial component was the reason for failure. All clinical scores significantly improved at 3 years follow-up and no further modification was demonstrated up to 6 years follow-up, with more than 80% rated good to excellent with all the evaluation scores. FTA and PTA had a significant difference at 3-years follow-up respect to pre-operative values (p < 0.01 and p < 0.03 respectively) and no further difference at 6-years follow-up. CONCLUSIONS:. The present data suggest that an all-poly tibial UKA is a viable option in patients under 60 years of age at the time of surgery, with isolated medial compartment OA, providing good to excellent KSS, Oxford, WOMAC, and Tegner scores in more than 80% of the patients at 3 to 6 years follow-up

We determined the cumulative survival rates, in arthroplasty of the knee, of three designs of tibial component, using a change of position on standard radiographs or revision for aseptic loosening as criteria of failure. The average migration of each of the three designs in the first postoperative year is known from roentgen stereophotogrammetric analysis reported by other authors. The ranking order of the components as judged by cumulative survival is the same as that determined by early migration. This finding supports the view that the measurement of early migration can predict late aseptic loosening and therefore that such measurements are clinically of value

Aims

The primary objective of this study was to compare the five-year tibial component migration and wear between highly crosslinked polyethylene (HXLPE) inserts and conventional polyethylene (PE) inserts of the uncemented Triathlon fixed insert cruciate-retaining total knee arthroplasty (TKA). Secondary objectives included clinical outcomes and patient-reported outcome measures (PROMs).

The purpose of this study was to evaluate a high flex porous tantalum metal monoblock component system implanted through a MIS technique. A fellowship trained surgeon proficient in MIS surgery performed 109 consecutive TKAs in 95 patients. Patients were implanted with a tantalum monoblock tibia and a fiber-metal cruciate-retaining high flex femur through a MIS midvastus approach. Ninety uncemented porous tantulum monoblock patellae and 19 cemented all polyethylene patellae were implanted. Knee Society scores and Knee Society radiographic scores were calculated in all patients. Follow-up for a minimum of 2 years was performed in 109 knees. The average follow up was 39 months. Sixty-six percent of the patients were female and 34% male. The average age was 66 years. The average preoperative Knee Society Knee score was 36. The average preop Knee Society Functional Score was 46. Osteoarthritis was the primary diagnosis in 104 knees. Rheumatoid arthritis and Hemophilia was the diagnosis in two knees each. The average Knee Society Knee Score improved to 89. The average Knee Society Function score improved to 86. 106 of the knees were rated good or excellent and three knees were rated poor. Two patellar revisions were performed for loose components and one for patellar misalignment. One patella fracture occurred that required ORIF. One femoral component was revised for loosening. There were nonprogressive radiographic lucencies demonstrated on 4 tibial components. One tibial component was rated loose. There were radiographic lucencies on 5 femoral components, all nonprogressive. There were two uncemented tantalum patellar components with stable radiolucencies. Early results in 109 consecutive porous tantalum metal tibial and high flex cruciate-retaining femoral components implanted through an MIS midvastus approach have a high rate of success at a minimum followup of two years

Aims

The aims of this study were: 1) to describe extended restricted kinematic alignment (E-rKA), a novel alignment strategy during robotic-assisted total knee arthroplasty (RA-TKA); 2) to compare residual medial compartment tightness following virtual surgical planning during RA-TKA using mechanical alignment (MA) and E-rKA, in the same set of osteoarthritic varus knees; 3) to assess the requirement of soft-tissue releases during RA-TKA using E-rKA; and 4) to compare the accuracy of surgical plan execution between knees managed with adjustments in component positioning alone, and those which require additional soft-tissue releases.

Aims

Loosening of components after total knee arthroplasty (TKA) can be associated with the development of radiolucent lines (RLLs). The aim of this study was to assess the rate of formation of RLLs in the cemented original design of the ATTUNE TKA and their relationship to loosening.

Stems improve the mechanical stability of tibial components in total knee replacement (TKR), but come at a cost of stress shielding along their length. Their advantages include resistance to shear, reduced tibial lift-off and increased stability by reducing micromotion. Longer stems may have disadvantages including stress shielding along the length of the stem with associated reduction in bone density and a theoretical risk of subsidence and loosening, peri-prosthetic fracture and end-of-stem pain. These features make long stems unattractive in the primary TKR setting, but often desirable in revision surgery with bone loss and instability. In the revision scenario, stems are beneficial in order to convey structural stability to the construct and protect the reconstruction of bony defects. Cemented and uncemented long stemmed implants have different roles depending on the nature of the bone loss involved.

This review discusses the biomechanics of the design of tibial components and stems to inform the selection of the component and the technique of implantation.

This randomised trial evaluated the outcome of a single design of unicompartmental arthroplasty of the knee (UKA) with either a cemented all-polyethylene or a metal-backed modular tibial component. A total of 63 knees in 45 patients (17 male, 28 female) were included, 27 in the all-polyethylene group and 36 in the metal-backed group. The mean age was 57.9 years (39.6 to 76.9). At a mean follow-up of 6.4 years (5 to 9.9), 11 all-polyethylene components (41%) were revised (at a mean of 5.8 years; 1.4 to 8.0) post-operatively and two metal-backed components were revised (at one and five years). One revision in both groups was for unexplained pain, one in the metal-backed group was for progression of osteoarthritis. The others in the all-polyethylene group were for aseptic loosening. The survivorship at seven years calculated by the Kaplan–Meier method for the all-polyethylene group was 56.5% (95% CI 31.9 to 75.2, number at risk 7) and for the metal-backed group was 93.8% (95% CI 77.3 to 98.4, number at risk 16) This difference was statistically significant (p <  0.001). At the most recent follow-up, significantly better mean Western Ontario and McMaster Universities Arthritis Index Scores were found in the all-polyethylene group (13.4 vs 23.0, p = 0.03) but there was no difference in the mean Knee injury and Osteoarthritis Outcome scores (68.8; 41.4 to 99.0 vs 62.6; 24.0 to 100.0), p = 0.36). There were no significant differences for range of movement (p = 0.36) or satisfaction (p = 0.23).

This randomised study demonstrates that all-polyethylene components in this design of fixed bearing UKA had unsatisfactory results with significantly higher rates of failure before ten years compared with the metal-back components.

Cite this article: Bone Joint J 2015;97-B:786–92.