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Bone & Joint Open
Vol. 4, Issue 4 | Pages 262 - 272
11 Apr 2023
Batailler C Naaim A Daxhelet J Lustig S Ollivier M Parratte S

Aims

The impact of a diaphyseal femoral deformity on knee alignment varies according to its severity and localization. The aims of this study were to determine a method of assessing the impact of diaphyseal femoral deformities on knee alignment for the varus knee, and to evaluate the reliability and the reproducibility of this method in a large cohort of osteoarthritic patients.

Methods

All patients who underwent a knee arthroplasty from 2019 to 2021 were included. Exclusion criteria were genu valgus, flexion contracture (> 5°), previous femoral osteotomy or fracture, total hip arthroplasty, and femoral rotational disorder. A total of 205 patients met the inclusion criteria. The mean age was 62.2 years (SD 8.4). The mean BMI was 33.1 kg/m2 (SD 5.5). The radiological measurements were performed twice by two independent reviewers, and included hip knee ankle (HKA) angle, mechanical medial distal femoral angle (mMDFA), anatomical medial distal femoral angle (aMDFA), femoral neck shaft angle (NSA), femoral bowing angle (FBow), the distance between the knee centre and the top of the FBow (DK), and the angle representing the FBow impact on the knee (C’KS angle).


The Bone & Joint Journal
Vol. 102-B, Issue 6 Supple A | Pages 158 - 162
1 Jun 2020
Griseti Q Jacquet C Sautet P Abdel MP Parratte S Ollivier M Argenson J

Aims

The aim of this study was to compare the ability of tantalum, 3D porous titanium, antibiotic-loaded bone cement, and smooth titanium alloy to inhibit staphylococci in an in vitro environment, based on the evaluation of the zone of inhibition (ZOI). The hypothesis was that there would be no significant difference in the inhibition of methicillin-sensitive or methicillin-resistant Staphylococcus aureus (MSSA/MRSA) between the two groups.

Methods

A total of 30 beads made of three different materials (tantalum/3D porous titanium and smooth titanium alloy) were bathed for one hour in a solution of 1 g vancomycin in 20 ml of sterile water for injection (bath concentration: 50 mg/mL). Ten 1 cm3 cylinders of antibiotic-loaded cement were also created by mixing standard surgical cement with 1 g of vancomycin in standardized sterile moulds. The cylinders were then placed on agar plates inoculated with MSSA and MRSA. The ZOIs were measured each day and the cylinders were transferred onto a new inoculated plate.


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_11 | Pages 35 - 35
1 Oct 2019
Argenson J Ollivier M Sautet P Grisetti Q Abdel MP Parratte S
Full Access

Introduction

Periprosthetic joint infection (PJI) remains the main cause of failure in primary and revision total knee arthroplasties (TKAs). Local delivery of antibiotics, mainly antibiotic-loaded bone cement (ALBC), is commonly employed to prevent PJI. Over the past decade, tantalum and porous titanium have been successfully utilized as metaphyseal fixation devices to address bone loss and improve biologic fixation during revision TKA. However, no study has examined the antimicrobial properties compared to bone cement. The purpose of this study was to compare the ability of tantalum, 3D porous titanium, antibiotic-loaded bone cement (ALBC) and smooth titanium alloy (STA) to inhibit Staphylococci bacterial agents in an in vitro medium environment, based on the evaluation of the zone of inhibition (ZOI) and the antibacterial activity duration. Our study hypothesis was that we will found no significant difference between groups to inhibit Methicillin-Sensitive or Methicillin-Resistant Staphylococcus aureus (MSSA/MRSA) agents.

Methods

Thirty beads made of 3 different materials (tantalum/ 3D porous titanium/ STA) were bathed during 1hour inside of a solution made of 1g vancomycin with 20-mL of sterile water for injection (bath concentration: 50 mg/mL). Ten 1cm3 cylinders were also created mixing standard surgical cement with 1g of Vancomycin in standardized sterile molds (ALBC beads). Finally, thirty beads made of tantalum/ 3D porous titanium/ STA were bathed in phosphate buffered saline solution to act as a control group. Cylinders were then placed on agar plates inoculated with MSSA and MRSA. Inhibition zone diameters were measured each day and cylinders were transferred onto a new inoculated plate. Inhibition zones were measured with a manual Vernier caliper and with automated software. The mean inhibition zones between groups were compared using the Wilcoxon Test.


The Bone & Joint Journal
Vol. 101-B, Issue 7 | Pages 848 - 851
1 Jul 2019
Sautet P Parratte S Mékidèche T Abdel MP Flécher X Argenson J Ollivier M

Aims

The aims of this study were to compare the mean duration of antibiotic release and the mean zone of inhibition between vancomycin-loaded porous tantalum cylinders and antibiotic-loaded bone cement at intervals, and to evaluate potential intrinsic antimicrobial properties of tantalum in an in vitro medium environment against methicillin-sensitive Staphylococcus aureus (MSSA).

Materials and Methods

Ten porous tantalum cylinders and ten cylinders of cement were used. The tantalum cylinders were impregnated with vancomycin, which was also added during preparation of the cylinders of cement. The cylinders were then placed on agar plates inoculated with MSSA. The diameter of the inhibition zone was measured each day, and the cylinders were transferred to a new inoculated plate. Inhibition zones were measured with a Vernier caliper and using an automated computed evaluation, and the intra- and interobserver reproducibility were measured. The mean inhibition zones between the two groups were compared with Wilcoxon’s test.


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_5 | Pages 33 - 33
1 Apr 2019
Bandi M Siggelkow E Oswald A Parratte S Benazzo F
Full Access

Introduction

Partial knee arthroplasty (PKA) has demonstrated the potential to improve patient satisfaction over total knee arthroplasty. It is however perceived as a more challenging procedure that requires precise adaptation to the complex mechanics of the knee. A recently developed PKA system aims to address these challenges by anatomical, compartment specific shapes and fine-tuned mechanical instrumentation. We investigated how closely this PKA system replicates the balance and kinematics of the intact knee.

Materials and Methods

Eight post-mortem human knee specimens (age: 55±11 years, BMI: 23±5, 4 male, 4 female) underwent full leg CT scanning and comprehensive robotic (KUKA KR140 comp) assessments of tibiofemoral and patellofemoral kinematics. Specimens were tested in the intact state and after fixed bearing medial PKA. Implantations were performed by two experienced surgeons.

Assessments included laxity testing (anterior-posterior: ±100 N, medial-lateral: ±100 N, internal-external: ±3 Nm, varus- valgus: ±12 Nm) under 2 compressive loads (44 N, 500 N) at 7 flexion angles and simulations of level walking, lunge and stair descent based on in-vivo loading profiles. Kinematics were tracked robotically and optically (OptiTrack) and represented by the femoral flexion facet center (FFC) motions. Similarity between intact and operated curves was expressed by the root mean square of deviations (RMSD) along the curves. Group data were summarized by average and standard deviation and compared using the paired Student's T-test (α = 0.05).


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_5 | Pages 114 - 114
1 Mar 2017
Riviere C Girerd D Ollivier M Argenson J Parratte S
Full Access

Background

A principle of Total Knee Arthroplasty (TKA) is to achieve a neutral standing coronal alignment of the limb (Hip Knee Ankle (HKA) angle) to reduce risks of implant loosening, reduce polyethylene wear, and optimise patella tracking. Several long-term studies have questioned this because the relationship between alignment and implant survivorship is weaker than previously reported. We hypothesize standing HKA poorly predicts implant failure because it does not predict dynamic HKA, dynamic adduction moment, and loading of the knee during gait. Therefore, the aim of our study is to assess the relationship between the standing (or static) and the dynamic (gait activity) HKAs.

Methods

We performed a prospective study on a cohort of 35 patients (35 knees) who were treated with a posterior-stabilized TKA for primary osteoarthritis between November 2012 and January 2013. Three months after surgery each patient had standardized digital full-leg coronal radiographs and was classified as neutrally aligned TKA (17 patients), varus aligned (9 patients), and valgus aligned (4 patients) (figure 1). Patients then performed a gait analysis for level walking and dynamic HKA and adduction moment during the stance phase of gait were measured.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_5 | Pages 117 - 117
1 Mar 2017
Riviere C Howell S Parratte S Vendittoli P Iranpour F Cobb J
Full Access

The mechanical alignment (MA) for Total Knee Arthroplasty (TKA) with neutral alignment goal has had good overall long-term outcomes. In spite of improvements in implant designs and surgical tools aiming for better accuracy and reproducibility of surgical technique, functional outcomes of MA TKA have remained insufficient. Therefore, alternative, more anatomicaloptions restoring part (adjusted MA (aMA) and adjusted kinematic alignment (aKA) techniques) or the entire constitutional frontal deformity (unicompartment knee arthroplasty (UKA) and kinematic alignment (KA) techniques) have been developed, with promising results. The kinematic alignment for TKA is a new and attractive surgical technique enabling a patient specific treatment. The growing evidence of the kinematic alignment mid-term effectiveness, safety and potential short falls are discussed in this paper. The current review describes the rationale and the evidence behind different surgical options for knee replacement, including current concepts in alignment in TKA. We also introduce two new classification systems for “implant alignments options” (Figure 1) and “osteoarthritic knees” (Figure 2) that would help surgeons to select the best surgical option for each patient. This would also be valuable for comparison between techniques in future research.

For figures/tables, please contact authors directly.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_2 | Pages 65 - 65
1 Jan 2017
Rivière C Iranpour F Cobb J Howell S Vendittoli P Parratte S
Full Access

The mechanical alignment (MA) for Total Knee Arthroplasty (TKA) with neutral alignment goal has had good overall long-term outcomes. In spite of improvements in implant designs and surgical tools aiming for better accuracy and reproducibility of surgical technique, functional outcomes of MA TKA have remained insufficient. Therefore, alternative, more anatomical options restoring part (adjusted MA (aMA) and adjusted kinematic alignment (aKA) techniques) or the entire constitutional frontal deformity (unicompartment knee arthroplasty (UKA) and kinematic alignment (KA) techniques) have been developed, with promising results. The kinematic alignment for TKA is a new and attractive surgical technique enabling a patient specific treatment. The growing evidence of the kinematic alignment mid-term effectiveness, safety and potential short falls are discussed in this paper. The current review describes the rationale and the evidence behind different surgical options for knee replacement, including current concepts in alignment in TKA. We also introduce two new classification systems for “implant alignments options” and “osteoarthritic knees” that would help surgeons to select the best surgical option for each patient. This would also be valuable for comparison between techniques in future research.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_1 | Pages 55 - 55
1 Jan 2017
Rivière C Girerd D Ollivier M Argenson J Parratte S
Full Access

A principle of Total Knee Arthroplasty (TKA) is to achieve a neutral standing coronal alignment of the limb (Hip Knee Ankle (HKA) angle) to reduce risks of implant loosening, reduce polyethylene wear, and optimise patella tracking. Several long-term studies have questioned this because the relationship between alignment and implant survivorship is weaker than previously reported. We hypothesize standing HKA poorly predicts implant failure because it does not predict dynamic HKA, dynamic adduction moment, and loading of the knee during gait. Therefore, the aim of our study is to assess the relationship between the standing (or static) and the dynamic (gait activity) HKAs.

We performed a prospective study on a cohort of 35 patients (35 knees) who were treated with a posterior-stabilized TKA for primary osteoarthritis between November 2012 and January 2013. Three months after surgery each patient had a standardized digital full-leg coronal radiographs and was classified as neutrally aligned TKA (17 patients), varus aligned (9 patients), and valgus aligned (4 patients). Patients then performed a gait analysis for level walking and dynamic HKA and adduction moment during the stance phase of gait were measured.

We found standing HKA having a moderate correlation with the peak dynamic varus (r=0.318, p=0.001) and the mean and peak adduction moments (r=0.31 and r=-0.352 respectively). In contrast we did not find a significant correlation between standing HKA and the mean dynamic coronal alignment (r=0.14, p=0.449). No significant differences were found for dynamic frontal parameters (dynamic HKA and adduction moment) between patients defined as neutrally aligned or varus aligned.

In our practice, the standing HKA after TKA was of little value to predict dynamic behaviour of the limb during gait. These results may explain why standing coronal alignment after TKA may have limited influence on long term implant fixation and wear.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_1 | Pages 24 - 24
1 Jan 2016
Argenson J Parratte S Flecher X Aubaniac J
Full Access

Treatment of osteoarthritis of the knee remains a challenging problem since the evolution of the disease may be different in each compartment of the knee, as well as the state of the ligaments. Total knee arthroplasty may provide a reliable long-lasting option but do not preserve the bone stock. In another hand, compartmental arthroplasty is a bone and ligament sparing solution to manage limited osteoarthritis of the knee affecting the medial, lateral or the patello-femoral compartment.1, 2, 3

Patient's selection and surgical indication are based on the physical examination and on the radiological analysis including full-length x-rays and stress x-rays. Clinical experience has shown the need for high flexion in patients who have both high flexibility and a desire to perform deep flexion.

Additionally the shape differences related to anatomy or the patient expectations after the surgery may also affect the surgeon decision. 4

The limited incision into the extensor mechanism allows a quicker recovery which represents a functional improvement for the patient additionally to the cosmetic result. A dedicated physiotherapy starting on the following day allowing weight bearing exercises protected by crutches and focusing on early mobilization and range of motion combined to a multimodal pain management approach is critical despite the type of individualized solution chosen for the patient knee. 5

Since bony landmarks may be different form a patient to another one as well as anatomical shapes, several tools have been developed in order to provide the surgeons an assisted tool during the surgery adapted to each knee, this include navigation, patient specific instrumentation and robotic surgery.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_1 | Pages 60 - 60
1 Jan 2016
Abdel MP Parratte S Budhiparama NC
Full Access

Whether to resurface the patella during a primary Total Knee Replacement (TKR) performed as a treatment of degenerative osteoarthritis remain a controversial issue. Patellar resurfacing was introduced because early implants were not designed to accommodate the native patella in an anatomic fashion during the range of motion. Complications related to patella resurfacing became a primary concern and have been associated with the variable revision rates often report post TKR. Subsequent modifications in implant design have been made to offer the surgeon option of leaving the patella un-resurfaced.

Numerous clinical trials have been done to determine the superiority of each option. Unfortunately, there is little consensus and surgeon preference remains the primary variable. One of the major reasons given to support patella resurfacing is to eliminate Anterior Knee Pain post operatively. However, studies have shown that this problem was not exclusively found in non-resurfaced patients so the author conclude that anterior knee pain is probably related to component design or to the details of the surgical technique, such as component rotation rather that whether or not the patella is resurfaced.

An increasing rate of complications with the extensor mechanism after patellar resurfacing led to the concept of selective resurfacing of the patella in TKR. Decision making algorithms with basis of clinical, radiographic and intraoperative parameters have been developed to determine which patients are suitable for patella resurfacing and which are suitable for patella non-resurfacing.

Finally, the continued study of this topic with longer follow up term in randomized, controlled, clinical trials remains essential in our understanding of patella in TKR. The development of joint registry will allow surgeons to draw conclusions on the basis of larger numbers of patients and will improve the reporting of the results of patellar non resurfacing in clinical trials. In general, surgeons in United States always resurface while their counterparts in Europe tend to never resurface.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_1 | Pages 25 - 25
1 Jan 2016
Argenson J Flecher X Parratte S Aubaniac J
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Improving the adaptation between the implant and the patient bone during total hip arthroplasty (THA) may improve the survival of the implant. This requires a perfect understanding of the tridimensional characteristics of the patient hip. The perfect evaluation of the tridimensional anatomy of the patient hip can be done pre-operatively using X-rays and CT-scan. All patients underwent a standard x-rays evaluation in the same center according to the same protocol. Pre-operatively, the frontal analysis of the hip geometry was performed and the optimal center of rotation, CCD angle, neck length and lever arm was analyzed to choose the optimal solution for proper balance of the hip in order to obtain adequate range of motion, appropriate leg length, and correct tension of the abductors muscles. Standard or lateralized monoblock stems can be valid or modular neck shape can be choosen among 9 available shape. These 9 frontal shapes are available in standard, anteverted or retroverted shapes, leading to 27 potential neck combinations. In case of important hip deformation, a custom implant can be used in order to balance the extra-medullar geometry without compromising the intra-medullary adaptation of the stem.

We prospectively included 209 hips treated in our institution with total hip arthroplasty performed using a supine Watson-Jones approach and the same anatomic stem. The mean patient age was 68 years and the mean BMI 26 Kg/m². Intra-operatively the sagittal anatomy of the hip was analyzed and standard, ante or retro modular necks were tested for the frontal shape defined pre-operatively.

According to the pre-operative frontal planning, non-standard necks were required in 24 % of the cases to restore the anatomy of the hip. Intra-operatively, a sagittal correction using anteverted neck was required in 5% of the cases and retroverted necks in 18% of the cases. Harris hip score improved from 56 to 95 points at min. 5 year follow-up. No leg length discrepancy greater than 1 cm was observed. Restoration of the lever arm (mean 39.3 mm, range 30 to 49 mm) and of the neck length (55.2, range 43 to 68 mm) was adapted for 95% compared to the non operate opposite side. Disturbed anatomy like in DDH or post-traumatic cases may require additional solutions to balance the hip such combined osteotomy or customized stem and neck.


The Bone & Joint Journal
Vol. 97-B, Issue 10_Supple_A | Pages 9 - 15
1 Oct 2015
Parratte S Ollivier M Lunebourg A Abdel MP Argenson J

Partial knee arthroplasty (PKA), either medial or lateral unicompartmental knee artroplasty (UKA) or patellofemoral arthroplasty (PFA) are a good option in suitable patients and have the advantages of reduced operative trauma, preservation of both cruciate ligaments and bone stock, and restoration of normal kinematics within the knee joint. However, questions remain concerning long-term survival. The goal of this review article was to present the long-term results of medial and lateral UKA, PFA and combined compartmental arthroplasty for multicompartmental disease. Medium- and long-term studies suggest reasonable outcomes at ten years with survival greater than 95% in UKA performed for medial osteoarthritis or osteonecrosis, and similarly for lateral UKA, particularly when fixed-bearing implants are used. Disappointing long-term outcomes have been observed with the first generation of patellofemoral implants, as well as early Bi-Uni (ie, combined medial and lateral UKA) or Bicompartmental (combined UKA and PFA) implants due to design and fixation issues. Promising short- and med-term results with the newer generations of PFAs and bicompartmental arthroplasties will require long-term confirmation.

Cite this article: Bone Joint J 2015;97-B(10 Suppl A):9–15.


The Bone & Joint Journal
Vol. 96-B, Issue 8 | Pages 1041 - 1046
1 Aug 2014
Ollivier M Frey S Parratte S Flecher X Argenson JN

There is little in the literature on the level of participation in sports which patients undertake after total hip replacement (THR). Our aims in this study were to determine first, the level of sporting activity, second, the predictive factors for returning to sporting activity, and third, the correlation between participation in sports and satisfaction after THR. We retrospectively identified 815 patients who had undergone THR between 1995 and 2005. All were asked to complete a self-administered questionnaire regarding their sporting activity. A total of 571 patients (71%) met the inclusion criteria and completed the evaluation. At a mean follow-up of 9.8 years (sd 2.9), 366 patients (64%) returned to sporting activity as defined by a University of California at Los Angeles (UCLA) score of > 5. The main reasons that patients had for refraining from sports were fear of dislocation (65; 31.6%), avoiding wear (52; 25.4%), and the recommendation of the surgeon (34; 16.6%). There was a significant relationship between higher post-operative participation in sport in those patients with a higher pre-operative Harris hip score (HHS) (p = 0.0074), motivation to participate in sporting activities (p = 0.00022) and a shorter duration of symptoms (p = 0.0034). Finally, there was a correlation between age (p = 0.00013), UCLA score (p = 0.012) and pre-operative HHS (p = 0.00091) and satisfaction.

In conclusion, we found that most patients participate in sporting activity after THR, regardless of the advice of their surgeon, and that there is a correlation between the level of participation and pre-operative function, motivation, duration of symptoms and post-operative satisfaction.

Cite this article: Bone Joint J 2014;96-B:1041–6


The Bone & Joint Journal
Vol. 96-B, Issue 7 | Pages 857 - 862
1 Jul 2014
Abdel MP Oussedik S Parratte S Lustig S Haddad FS

Substantial healthcare resources have been devoted to computer navigation and patient-specific instrumentation systems that improve the reproducibility with which neutral mechanical alignment can be achieved following total knee replacement (TKR). This choice of alignment is based on the long-held tenet that the alignment of the limb post-operatively should be within 3° of a neutral mechanical axis. Several recent studies have demonstrated no significant difference in survivorship when comparing well aligned versus malaligned TKRs. Our aim was to review the anatomical alignment of the knee, the historical and contemporary data on a neutral mechanical axis in TKR, and the feasibility of kinematically-aligned TKRs.

Review of the literature suggests that a neutral mechanical axis remains the optimal guide to alignment.

Cite this article: Bone Joint J 2014;96-B:857–62.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_34 | Pages 8 - 8
1 Dec 2013
Argenson J Ollivier M Parratte S Flecher X Aubaniac J
Full Access

Introduction:

Recent studies have concluded that gender influences hip morphology at the time of surgery as well as dysplastic development of the hip. This may lead to a particular choice of implant including stem design and/or neck modularity. In this study we hypothesized that not only gender but also morphotype and etiology (primary osteoarthritis versus aseptic osteonecrosis) may be a significant factor to predict the anatomy of the hip at the time of total hip arthroplasty (THA).

Methods:

We reviewed 690 patients undergoing THA for primary arthritis (OA) or avascular osteonecrosis (AVN) between April 2000 and June 2005 and stratified each into three groups based on their anatomic constitution: endomorph (EN), ectomorph (ECT), or mesomorph (ME) (determined by the ratio: pelvic width/total leg length measured on full-length X-rays). Two independent observers measured twice four parameters on preoperative CT scan: neck-shaft-angle angle (NSA), femoral offset value (FO), helitorsion (Ht) value and femoral neck anteversion (Av).


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XL | Pages 137 - 137
1 Sep 2012
Parratte S Lesko F Zingde S Anderle M Mahfouz M Komistek R Argenson J
Full Access

Introduction

Previous fluoroscopic studies compared total knee arthroplasty (TKA) kinematics to normal knees. It was our hypothesis that comparing TKA directly to its non-replaced controlateral knee may provide more realistic kinematics information. Using fluoroscopic analysis, we aimed to compare knee flexion angles, femoral roll-back, patellar tracking and internal and external rotation of the tibia.

Material and methods

15 patients (12 women and 3 men) with a mean age of 71.8 years (SD=7.4) operated by the same surgeon were included in this fluoroscopic study. For each patient at a minimum one year after mobile-bearing TKA, kinematics of the TKA was compared to the controlateral knee during three standardized activities: weight-bearing deep-knee bend, stair climbing and walking. A history of trauma, pain, instability or infection on the non-replaced knee was an exclusion criteria. A CT-scan of the non-replaced knee was performed for each patient to obtain a 3-D model of the knee. The Knee Osteoarthitis Outcome Score (KOOS) was also recorded.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 282 - 282
1 Sep 2012
Lustig S Parratte S Servien E Argenson J Neyret P
Full Access

Introduction

It is documented in the literature the very good results of lateral unicompartmental knee arthroplasty (UKA) when the standard accepted indications are followed. In our experience these indications can be extended to include post-traumatic osteoarthritis (OA) with malunion secondary to tibial plateau fracture. We report our results concerning 15 UKAs in these particular situations.

Material and methods

From 1985 to 2009, we performed 15 lateral UKAs in 15 patients for post traumatic OA secondary to malunion following a tibial plateau fracture. 7 were female and 8 male. The mean age of the patients at the time of the index procedure was 45±17 years and the mean delay from initial trauma was 5.4 years. The average follow-up was 108 months (range 12–265 months).


The Journal of Bone & Joint Surgery British Volume
Vol. 94-B, Issue 5 | Pages 609 - 614
1 May 2012
Flecher X Blanc G Sainsous B Parratte S Argenson J

We describe the results of 81 consecutive revision total hip replacements with impaction grafting in 79 patients using a collared polished chrome–cobalt stem, customised in length according to the extent of distal bone loss. Our hypothesis was that the features of this stem would reduce the rate of femoral fracture and subsidence of the stem.

The mean follow-up was 12 years (8 to 15). No intra-operative fracture or significant subsidence occurred. Only one patient suffered a post-operative diaphyseal fracture, which was associated with a fall. All but one femur showed incorporation of the graft. No revision for aseptic loosening was recorded.

The rate of survival of the femoral component at 12 years, using further femoral revision as the endpoint, was 100% (95% confidence interval (CI) 95.9 to 100), and at nine years using re-operation for any reason as the endpoint, was 94.6% (95% CI 92.0 to 97.2).

These results suggest that a customised cemented polished stem individually adapted to the extent of bone loss and with a collar may reduce subsidence and the rate of fracture while maintaining the durability of the fixation.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 466 - 466
1 Nov 2011
Aubaniac J Parratte S Argenson JA
Full Access

Treatment of limited osteoarthritis of the knee remains a challenging problem. Total knee arthroplasty may provide a reliable long-lasting option but do not preserve the bone stock. In another hand, compartmental arthroplasty with or without osteotomy is a bone and ligament sparing solution to manage limited osteoarthritis of the knee. Considering the renewed interest for combined compartmental implants we aimed to evaluate the average 12-year clinical and radiological outcome of a consecutive series of patients treated with compartmental knee arthroplasty combined or not with osteotomy.

We retrospectively reviewed all 255 patients (274 knees) treated in our institution with a compartmental arthroplasty combined or not with an osteotomy for a diagnosis of either bi or tricompartmental osteoarthritis of the knee between April 1972 and December 2000. The series included: 100 cases of combined lateral and medial UKA, 77 combined medial UKA and patello-femoral arthroplasty (PFA), 19 cases of combined Bi-UKA and PFA, 14 cases of UKA and high tibial osteotomy (HTO), 7 cases of combined lateral-UKA and PFA and HTO, 16 cases of combined lateral-UKA and PFA and 13 cases of combined bi-UKA and HTO.

Patient’s selection and surgical indication was based on the physical exam and on the radiological analysis including full-length x-rays and stress x-rays. Clinical and radiological evaluations were performed at a minimum follow-up of 5 years (mean, 12 years; range, 5–23 years) by an independent observer.

The Knee Society knee and function scores improved respectively from 43 to 89 and from 47 to 90 at last-follow-up. The mean active knee flexion improved from 116° ± 6° (range, 100°–145°) pre-operatively to 129° ± 5° (range, 117°–149°) at final follow-up. The restoration of the mechanical axis of the knee was achieved in all the cases. Dramatic failures were observed for patient with uncemented PFA. Considering revision for any reason as the endpoint, the 17-years survivorship was 0.68 (95% confidence interval: 0.62 to 0.75).

Our results suggested that combined compartmental arthroplasty with or without osteotomy can restore function and alignment of the knee in compartmental arthritis. This combined surgery represents a bone and ligament sparing alternative to TKA which can be considerate as a true minimally invasive solution.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 530 - 531
1 Nov 2011
Buord J Parratte S Flécher X Pauly V Argenson J
Full Access

Purpose of the study: Three-screw fixation is the classical treatment for true Garden I in the elderly patient. Complication rates have been high in the literature. Furthermore, in this context outcome for arthroplasty after failed osteosynthesis is less satisfactory than first-intention arthroplasty. This is why functional treatment of Garden I fractures of the neck of the femur has been proposed, including rapid return to the upright position and strict radiographic and clinical control. The purpose of this work was to first evaluate the results of this management option for true Garden I fractures in patients aged over 65 years and second to search for factors predictive of secondary displacement.

Material and methods: All patients aged over 65 years and admitted to the unit for true Garden I fractures from January 2005 to December 2006 were included in this prospective study. A functional treatment including early return to the upright position and walking test on day 1 was instituted, followed by radiographic controls on days 2, 7, 14, 21, and 45 then at 3 months and one year. Referral to a rehabilitation centre at discharge on day 5 was scheduled if there was no displacement. In the event of a displacement, arthroplasty was performed. Fifty-seven patients, mean age 82.8±8.5 years (range 65–99) were included. The radiographic and clinical follow-ups were made by an independent observer.

Results: The displacement rate was 29.8%. These patients were treated by arthroplasty. In the group of patients without displacement, at minimum one year follow-up, there has been no need for surgical revision excepting one case of osteonecrosis at one year requiring implantation of a total prosthesis. The mean Parker score in this group was 6.4 and the mean Harris score 83, it was 85 in the arthroplasty group. Among the predictive factors identified at multivariate analysis were: age, gender, side, type of fracture, fracture orientation, degree of valgus or sagittal displacement, general status. Displacement was not statistically predictive.

Discussion: The results of our prospective study show that 70% of patients included were treated successfully without surgery, confirming reports in the literature and justifying utilisation of this management strategy.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 527 - 527
1 Nov 2011
Parratte S Since M Pauly V Aubaniac J Argenson J
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Purpose of the study: It has been demonstrated that the anatomy of the distal femur differs by gender. The ratio of the mediolateral/anteroposterior distance, the shape of the distal femur, and the orientation of the trochlea differ between males and females. To adapt to these differences, prostheses specifically designed for female patients (TKAgender) were developed. The purpose of our study was to compare the first objective and subjective outcomes with these prostheses.

Material and methods: Thirty women who underwent bilateral surgery within a six month interval for degenerative joint disease of the knee between March 2006 and March 2008 were included in a comparative prospective study. The side receiving the gender implant was determined at random. Operative and postoperative protocols were the same excepting the femoral implant. Patients were not informed of which knee had received the gender prosthesis. Mean age in this series was 67 years and mean BMI 26. All implants were cemented. At minimum one year follow-up, objective and subjective analysis included specific questions concerning preference and quality of life presented by an independent observer.

Results: The Knee Society clinical scores were comparable in the two groups, as were the results for the different items of the KOOS score. For preferences: the patients preferred the gender knee in 75% of the cases (p< 0.01), they reported less noise or cracking sounds in the anterior part of the knee for 68% (p=0.03) and had the impression that the knee recovered faster in 64% (p=0.04).

Discussion: To our knowledge, this is the first report of results concerning implants specifically designed for female patients. At short-term, the only difference in the patients’ preference was a subjective feeling of less impairment for the patellar track. It will be interesting to follow these patients to assess the long-term impact on the patellofemoral articulation.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 440 - 440
1 Nov 2011
Parratte S Kilian P Lecorroller T Pauly V Champsaur P Argenson J
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Most of computer-assisted computer assisted system rely on the peri-operative acquisition of the anterior pelvic plane defined as the plane crossing the two anterior iliac spine and the symphysis. The goal of this study was to evaluate in vivo and in vitro the accuracy of the anterior pelvic plane acquisition, considered as the reference for computer-assisted total hip arthroplasty (THA).

Cup placement was performed using an imageless computer-assisted system in thirty patients during THA. Post-operatively the position of the cup was evaluated on computed tomography using a validated tridimensional software. The differences between the perioperative and postoperative angles for abduction and anteversion were compared using a two-group pair test.

On two cadavers four clinicians performed ten times the anterior pelvic plane acquisition using three Methods: percutaneously, with ultrasound and by direct bony acquisition defined as the reference. The mean error for each anterior pelvic plane acquisition method was compared using a univariate variance model for repeated measurements.

In vivo, the mean difference between the perioperative and postoperative abduction angles was 4° and not statistically significant. For anteversion, the difference was 4° and not significant in patients with BMI < 27. The difference was 11° and significant in patients with BMI > 27 (p< 0.001). In vitro, the mean errors for rotation and tilt were respectively 3.8 ° and 19.25 ° for cutaneous acquisition, 2.8° and 6.2° for ultrasound acquisition method. The errors were statistically higher with the percutaneous method (p< 0.001).

According to our results, the accuracy of the standard percutaneous acquisition method of the anterior pelvic plane in computer-assisted THA is limited. The ultrasound acquisition method may represent a reliable alternative.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 537 - 537
1 Nov 2011
Hémon Y Parratte S Aubaniac J Kerbaul F Argenson J
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Purpose of the study: Besides enabling a precise calculation of the needs for blood (in ml) for each type of orthopaedic surgery, an adequate estimation of average total blood loss (TBL) as a function of total blood volume (TBV) enables initiation of blood sparing techniques. Thus, when the balance is negative, erythropoietin could be advisable. The purpose of this work was to analyse the impact of prescribing erythropoietin as a function of the expected blood balance on the rate of homologous blood transfusions. We also wanted to determine the financial impact of this prescription strategy.

Material and methods: This prospective study included 229 patients (153 THA and 76 TKA) who underwent surgery from January 2005 to December 2008 with a standard anaesthesia, analgesia and surgical protocol. TBL was considered to be 10% of TBV for THA and TKA. Mean gain in serum haemoglobin (Hb) per injection of erythropoietin (1 ampoule Eprex) was 0.8 g/dl. Using the patient’s Hb level at the preop exam (Hbpreop), the anaesthetist determined the volume available (VA) for each patient and for each type of operation. When VA was negative, the Hb needed to reach the desired level (HbA) so that VA=0 (zero risk of transfusion) was calculated. The number of Eprex ampoules prescribed (amp) was determined from the formula: (HbA-Hbpreop)/0.8. Hb levels on day 0, day 1, day 3(discharge) and day 28 were noted, as were the number of homologous transfusions and the total number of ampoules of Eprex delivered.

Results: Sixty-six patient received one amp (33.2%), 96 had two amp (42%), 40 three amp (17.5%) and 17 four amp (7.4%). For 220 patients (92%), Eprex delivered was within the approved dose (92%). The mean Hb levels were: Hbpreop=12.4, HbA=13.5, Hbd0=13.9, Hbdischarge=11.2, and Hbd28=11.9. Total consumption was 456 amp instead of 916 (229x4), i.e. a savings of 460 amp corresponding to 173 880 euros (460 x 378 euros). There were six homologous transfusions (2.6%).

Discussion: In orthopaedic surgery, adapted prescription of erythropoietin as a function of the TBL enabled, in this series, a simplification of the prescription procedure and avoided the risks related to high Hb levels > 15g with a financial savings of 760 euros per operation (173880 euros for 229 patients) without increasing the rate of homologous transfusion. This strategy is currently being evaluated for prosthesis revision surgery.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 408 - 408
1 Nov 2011
Argenson JA Parratte S Aubaniac J
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Improving the adaptation between the implant and the patient bone during total hip arthroplasty (THA) may improve the survival of the implant. This requires a perfect understanding of the tridimensional characteristics of the patient hip. The perfect evaluation of the tridimensional anatomy of the patient hip can be done pre-operatively using CT-scan and in case of important hip deformation, a custom implant can be used. When this solution is not available, modular necks may be a reliable alternative using standard x-rays and intraoperative adaptation. We aimed to evaluate:

The usefulness of modular neck to restore the anatomy of the hip and

the short-term clinical and radiological results of a consecutive series of THA using modular neck.

We prospectively included 209 hips treated in our institution with a modular neck total hip arthroplasty between January 2006 and December 2007. All patients underwent a standard xrays evaluation in the same center according to the same protocol. Pre-operatively, the frontal analysis of the hip geometry was performed and the optimal center of rotation, CCD angle, neck length and lever arm was analyzed to choose the optimal modular neck shape among 9 available shape. These 9 frontal shapes are available in standard, anteverted or retroverted shapes, leading to 27 potential neck combinations. The mean patient age was 68 years and the mean BMI 26 Kg/m2 All the procedures were performed supine using a Watson-Jones approach and the same anatomic stem. Intra-operatively the sagittal anatomy of the hip was analyzed and a standard, ante or retro modular necks were tested for the frontal shape defined pre-operatively.

According to the pre-operative frontal planning, nonstandard necks were required in 24 % of the cases to restore the anatomy of the hip. Intra-operatively, a sagittal correction using anteverted neck was required in 5% of the cases and retroverted necks in 18% of the cases.

Harris hip score improved from 56 to 95 points at last follow-up. No leg length discrepancy greater than 1 cm was observed. Restoration of the lever arm (mean 39.3 mm, range 30 to 49 mm) and of the neck length (55.2, range 43 to 68 mm) was adapted for 95% compared to the non operate opposite side. No loosening was observed.

According to our results modular neck combined are useful and reliable to restore optimal hip geometry and in this series 25% of the patient would have had imperfect extra-medullary hip geometry with a standard prosthesis. The good clinical and radiological short-term results should be confirmed at longer follow-up.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 430 - 430
1 Nov 2011
Argenson J Parratte S Flecher X Aubaniac J
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Unicompartmental knee arthroplasty (UKA) is a logic procedure when osteoarthritis or avascular necrosis is limitad to one femorotibial compartment. The indications for the procedure includes osteoarthrosis or osteonecrosis with full-thickness loss of articular cartilage limited to one of the tibiofemoral knee compartments. Physical examination should ensure full range of knee motion. Frontal and sagittal knee stability has to be tested. A particular attention should be given to the state of the anterior cruciate ligament. The status of the patellofemoral joint should be analysed by physical examination and patellofemoral view at 30, 60 and 90° of flexion. Preoperative anteroposterior varus and valgus stress radiographs should be done to confirm the complete loss of articular cartilage in the involved compartment, the full thickness cartilage in the opposite compartment and the possibility of full correction of the deformity to neutral.

The so-called minimally invasive surgery (MIS) procedure using a specific instrumentation is able to provide quicker recovery since the extensor mechanism disruption is eliminated. More importantly the radiological evaluation has shown that precise implantation of the components is possible with an MIS approach which is important for the long term results of the arthroplasty. The clinical results at ten years of follow-up of cemented metal-backed UKA performed through a conventional approach have shown results comparable to those obtained with total knee arthroplasty. The in vivo kinematic evaluation of patients implanted with UKA has shown that kinematics similar to the normal knee can be obtained, enhancing the importance of a functional anterior cruciate ligament.

Recent design improvements have increased the femorotibial area of contact to accommodate high flexion angles. Additionally our experience has demonstrated that modern UKA is a valid alternative for young and active patients with unicompartmental tibiofemoral noninflammatory disease, including both osteoarthritis and avascular necrosis. Compared to medial UKA lateral UKA represents in our experience only 5% of all UKA implantations.

However the long term results of lateral UKA compares at least equally with those reported for medial UKA.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 174 - 174
1 May 2011
Parratte S Sorenson M Dahm D Larson D O’Byrne M Pagnano M Stuart M Smith A Berry D
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Introduction: The International Knee Documentation Committee (IKDC) recommends use of the IKDC score to document subjective, objective and functional ACL outcome. To further improve knowledge concerning patient QOL after ACL reconstruction, an additional specific QOL questionnaire was developed. Using a combination of univariate and multivariate analysis the patient factors and surgical factors that influenced QOL 5- years after ACL reconstruction were determined.

Materials: 500 patients operated on for arthroscopic ACL reconstruction at our institution between 1997 and 2001 were prospectively enrolled. Patient psychosocial profile, sport expectations, knee exam, type of graft, associated lesion, type of anesthesia, complications, IKDC, KT 2000 at 6 moths, 1 year and 2 years were recorded. At five years, patients were asked to complete a 5-subscale validated QOL questionnaire for ACL deficiency. A multivariate analysis was performed to identify the factors influencing 5-year QOL.

Results: 203 patients completed the 5-years QOL questionnaire. Responders did not statistically differ from non responders. Patient subjective factors such as: patient expectations, pre-operative symptoms, work-school concerns, recreations concerns, social and psycho-social concerns were significantly (p< 0.05) and independently associated with the five-year QOL results. Objective factors such as meniscus tears and results of the KT 2000 (p< 0.05) were the two surgical factors correlated with 5-year QOL.

Discussion: In this large prospective study, most of the factors influencing the 5-year QOL results after ACL reconstruction were related to patient expectations, psycho-social, symptoms and work-sport concerns. The presence of a meniscus tear and greater KT 2000 laxity also contributed to poorer 5-year QOL results.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 216 - 216
1 May 2011
Parratte S Amphoux T Kolta S Gagey O Skalli W Bouler J Argenson J
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Introduction: The incidence of contralateral, second hip fractures after a first hip fracture is as high as 20% in the elderly. Femoroplasty using an injectable and resorbable bi-phosphonate loaded bone substitute to prevent controlateral hip fracture may represent a promising preventive therapy. We aimed to evaluate the biomechanical consequences of the femoroplasty using this bone substitute.

Materials and Methods: Twelve paired human cadaveric femora from donors with a mean age of 86 years (7 women and 6 men) were randomly assigned for femoroplasty and biomechanically tested for fracture load against their native contralateral control. Anterior–posterior and lateral radiographs and DXAscan’s were made before injection. Femoroplasty were performed under fluoroscopic guidance with an injectable and resorbable bi-phosphonate loaded bone substitute. All femurs were fractured by simulating a fall on the greater trochanter by an independent observer.

Results: Mean T-score of the tested femur were −3. Bone density was comparable for each pair of femur. All the observed fractures were Kyle II throchanteric fractures. Mean fracture load was 2786 Newton in the femoroplasty group (group F) versus 2116 Newton in the control group (group C) (p< 0.001). Fracture loads were always higher in the group F: mean 41.6% (mini: 1.2%/maxi:102.1%). Effect of femoroplasty was significantly superior for women and also correlated to initial bone density (p< 0.0001).

Discussion:According to our results, femoroplasty with an injectable and resorbable bi-phosphonate loaded bone substitute can provide significant biomechanical reinforcement of the proximal femur to prevent controlateral fracture.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 93 - 93
1 May 2011
Parratte S Argenson J Since M Pierre PB Pauly V Aubaniac J
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Introduction: Women have gender specific shape of the distal femur. To fit these gender characteristics, gender specific femoral implants were developed for total knee arthroplasty (TKA). We aimed to compare

objective and subjective functional improvement;

patient satisfaction and preference and

cost-utility ratio after gender specific TKA or standard component implanted on the same women.

Materials and Methods: 30 women (60 knees) operated on successively (6 months in between) for a bilateral TKA between March 2006 and March 2008 by the same surgeon were included in this prospective study. The same surgical protocol and the same post-operative management protocol were applied for both sides. Mean age was 67±3 and mean BMI 26±4 Kg/m2. At a minimum follow-up of one year, evaluation objective and subjective functional improvement, patient satisfaction and preference and cost-utility analysis were performed double blind.

Results: Knee Society knee score and Knee Osteoarthritis Outcome Score (KOOS) improvements were comparable in both groups. However, 75% of the women preferred their gender TKA (p< 0.001). 68% of the women described less crepitus or anterior knee bothering after gender TKA (p=0.003) and 64% had faster recovery with the gender implant (p< 0.001). The cost-utility analysis was favorable for the gender knee.

Discussion: No objective or subjective superiority in terms of functional improvement was shown with gender specific implants at this short-term follow-up. However significant differences in terms of patient satisfaction and preference and a favorable cost-utility analysis were observed. These results should now be confirmed at longer-follow-up. Despite comparative functional improvement, patient satisfaction and preference were higher for the side implanted with a gender specific TKA in this prospective comparative study.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_III | Pages 387 - 387
1 Jul 2010
Flecher X Pearce O Parratte S Grisoli D Helix M Aubaniac J Argenson J
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Introduction and Method: For 16 years, now, we have been using custom made femoral stems (titanium stem, HA coated) based on preoperative patient CT scans in young patients presenting with symptomatic osteoarthritis of the hip. The aim was to provide optimum initial fit-and-fill of the stem in the femoral medullary canal, conferring the best chance of secondary osteoin-tegration. This, with a goal of long term survivorship. The custom stem also enables dialling-in correction of the (often abnormal) femoral neck version (in young patients presenting with arthritis) to a more normalised 15 degrees of anteversion.

Results: We present the long term results (5–16 year, mean of 10 years), clinical, survivorship and radiological, of 312 primary total hip arthroplasties in 280 patients, all of whom were under the age of 50 years of age (mean age 40).

At 10 years we have a survivorship, if femoral aseptic loosening is used as an end point, of 97.6%. There was a deep infection rate of 1.2%, and a dislocation rate of 1.9%. There were no cases of thigh pain, and no intra-operative femoral neck/shaft fractures.

Discussion: The under 50’s with hip arthritis requiring total hip arthroplasty are a highly challenging group, they are young, active and tend to have distorted anatomy. Our results are superior to those previously published using either cemented or standard uncemented stems. Thus, justifying the increased initial financial outlay on the custom-made stem.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 359 - 359
1 May 2010
Parratte S Mahfouz M Booth R Argenson J
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Introduction: morphological analysis of the general shape of the bones and of their particular variations according to the patient age, gender and pathology is an important step to improve the orthopedic management. We aimed to performed a gender specific analysis of the bi and tridimensional anatomy of the distal femur in vitro and in vivo.

Materials and Methods: in vitro data were obtained from CT-scan performed on 92 dry men femurs and 52 dry women femurs. Using a manual contouring method and a segmentation method, tridimensional reconstructions were obtained and according to two different algorithms, the regions of discrepancies between men and women were determined. An automatic calculation of 59 defined measurements was then performed. In vivo data providing from 59 CT-scans of men femur and 73 CT-scan of women femurs were acquired. Standardized bidimensional measurements at the level of the trochlear cut were performed.

Results: in vivo, statistically significant differences were observed for the: medio-lateral distance (M-Ld women=7.4±0.4cm vs M-Ld men=8.4±0.5cm; p< 0.0001), anteroposterior distance (A-Pd women=5.9±0,4cm vs A-Pd men= 6.4±0.4cm; p< 0.0001) and for the ratio anterior-posterior distance/medio-lateral distance (p< 0.0001). The trochlear groove angle was comparable in the two groups. In vitro, the tridimensional shape of the distal femur was more trapezoidal in women than in men. Medio-lateral distances were also statistically greater in men than in women (p< 0.01), the ratio anterior-posterior distance/medio-lateral distance was also statistically greater in men than in women (p< 0.01) and the Q angle more open in women than in men (p< 0.01).

Discussion: Three types of differences between men and women were observed in this gender specific evaluation of the distal femur anatomy. First, for a same anteroposterior distance, the medio-lateral distance was smaller in women. Second, the global shape of the distal femur was more trapezoidal in women and third the Q angle was more open in women. This gender specific anatomy should be clinically considered when performing total knee arthroplasty in women and gender specific implants may be required.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 274 - 275
1 May 2010
Parratte S Flecher X Vesin O Brunet C Aubaniac J Argenson J
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Introduction: Due to the diversity of the prosthetic implants for hip arthroplasty, a better matching between the implant and the intra and extra-medullary characteristic of the patient anatomy is now possible. This adaptation however requires a perfect understanding of the tridimensional characteristics of the patient hip anatomy. Little data are available in the literature. We aimed to analyze the muscular and bony anatomy of the hip at the time of arthroplasty.

Material and Methods: data acquisition was performed according a standardized CT-scan in the same center for all patients within the standard workup before arthroplasty. Standardized measurements were obtained after automatic tridimensional bone reconstructions using dedicated software. 549 femurs in 469 patients including primitive coxarthrosis (COX), dysplasic development of the hip (DDH) and aseptic osteonecrosis (ONA) were analyzed. Mean age was 58 and 70% of the patients were women. Tridimensional reconstruction of the muscular anatomy of the hip was performed for 30 patients using manual contouring on dedicated software. Characteristics of the bony and muscular anatomy were then analyzed according to the etiology and correlations between bony and muscular anatomy were evaluated.

Results: Concerning the bone analysis, mean offset was 23.2 ±1.5mm in the DDH group, 40.5±1.2 mm in the COX group and 29.6± 0.9mm in the ONA group(p< 0.001). Neck-shaft angle was 132±25º in the DDH group, 130±0.5º in the COX group and 134±1º in the ONA group (p< 0.001). Mean anteversion was 33±3.5º in the DDH group, 25±3.8º in the COX group and 16±3.2º in the ONA group (p< 0.001). Concerning the muscular analysis, gluteus medius and minimus volumes were correlated with the body mass index and with the gender, but not with patient age (p: NS). Location of the muscular insertion of the gluteus medius and minimus on the greater trochanter were correlated with the femoral anteversion.

Discussion: The results of our study demonstrated that bony and muscular anatomical characteristics were correlated with the etiology of the degenerative joint disease, with the patient body mass index and gender. Surgeons should be aware of these characteristics to improve the patient anatomy reconstruction during the arthroplasty.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 326 - 326
1 May 2010
Parratte S Sah A Aubaniac J Scott R Agenson J
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Introduction: The data reporting clinical and radiological outcomes after modern unicompartmental knee arthroplasty (UKA) for spontaneous avascular osteonecrosis are limited. We hypothesized that UKA for spontaneous osteonecrosis may be as reliable and durable as it is for osteoarthritis.

Materials and Methods: We retrospectively reviewed 40 cemented UKA operated for spontaneous osteonecrosis of the knee in two different centers between 1989 and 2004. Twenty-six patients were women and 14 men, mean patient age was 67 years (range, 45 to 84) and mean body mass index was 27.4 Kg/m2 (range, 18 to 44). Clinical and radiological evaluations were performed by an independent observer in each center according to the same protocol at a minimum follow-up of 3 years (mean 8 years; range, 3–17.5 years).

Results: The mean Knee Society Knee score improved from 60 preoperatively to 95 post-operatively. The mean Knee Society Function score improved from 50 preoperatively to 89 post-operatively. Restoration of an appropriate lower-limb mechanical axis was achieved for 36 knees (90%). Two knees were revised for aseptic loosening. The Kaplan–Meier survivorship was 95% at 12 years.

Discusssion and conclusion: Our data suggest UKA is a reasonable solution for restoring clinical function and radiological lower-limb alignment for spontaneous osteonecrosis of the knee, with a durable survivorship.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 297 - 297
1 May 2010
Flecher X Parratte S Aubaniac J Argenson J
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A clinical and radiographic study was conducted on 97 total hip arthroplasties (79 patients) performed for congenital hip dislocation using three-dimensional custom cementless stem. The mean age was 48 years (17 to 72). The mean follow up was 123 months (83 to 182).

According to Crowe, there were 37 class 1, 28 class 2, 13 class 3 and 19 class 4. The average lengthening was 25 mm (5 to 58 mm), the mean femoral anteversion 38.6° (2° to 86°) and the correction in the prosthetic neck −23.6° (71° to 13°). The average Harris hip score improved from 58 to 93 points. Six hips (6.2%) required a revision. The survival rate was 97.7% ± 0.3% at 13 years.

Custom cementless stem allows anatomical reconstruction and good functional results in a young and active population with disturbed anatomy, while avoiding a femoral osteotomy.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 227 - 228
1 May 2009
Bicknell R Boileau P Chuinard C Jacquot N Parratte S Trojani C
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The purpose of this study was to review the results of biceps tenodesis and biceps reinsertion in the treatment of type II SLAP lesions.

We conducted a retrospective cohort study of a continuous series of patients. Only isolated type II SLAP lesions were included: twenty-five cases from January 2000 to April 2004. Exclusion criteria included associated instability, rotator cuff rupture and previous shoulder surgery. Ten patients (ten men) with an average age of thirty-seven years (range, 19–57) had a reinsertion of the long head of the biceps tendon (LHB) to the labrum with two suture anchors. Fifteen patients (nine men and six women) with an average age of fifty-two years (range, 28–64) underwent biceps tenodesis in the bicipital groove. All patients were reviewed by an independent examiner.

In the reattachment group, the average follow-up was thirty-five months (range, 24–69); three patients underwent subsequent biceps tenodesis for persistent pain, three others were disappointed because of an inability to return to their previous level of sport, and the remaining four were very satisfied. The average Constant score improved from sixty-five to eighty-three points. In the tenodesis group, the average follow-up was thirty-four months (range, 24–68). No patient required revision surgery. Subjectively, one patient was disappointed (atypical residual pain), two were satisfied and twelve were very satisfied. All patients returned to their previous level of sports, and the average Constant score improved from fifty-nine to eighty-nine points.

The results of labral reattachment were disappointing in comparison to biceps tenodesis. Thus, arthroscopic biceps tenodesis can be considered as an effective alternative to reattachment in the treatment of isolated type II SLAP lesions. By moving the origin of the biceps to an extra-articular position, we eliminated the traction on the superior labrum and the source of pain; furthermore, range of motion and strength are unaltered allowing for a return to a pre-surgical level of activity.


The Journal of Bone & Joint Surgery British Volume
Vol. 91-B, Issue 3 | Pages 351 - 356
1 Mar 2009
Parratte S Argenson JA Pearce O Pauly V Auquier P Aubaniac J

We retrospectively reviewed 35 cemented unicompartmental knee replacements performed for medial unicompartmental osteoarthritis of the knee in 31 patients ≤50 years old (mean 46, 31 to 49). Patients were assessed clinically and radiologically using the Knee Society scores at a mean follow-up of 9.7 years (5 to 16) and survival at 12 years was calculated. The mean Knee Society Function Score improved from 54 points (25 to 64) pre-operatively to 89 (80 to 100) post-operatively (p < 0.0001). Six knees required revision, four for polyethylene wear treated with an isolated exchange of the tibial insert, one for aseptic loosening and one for progression of osteoarthritis.

The 12-year survival according to Kaplan-Meier was 80.6% with revision for any reason as the endpoint. Despite encouraging clinical results, polyethylene wear remains a major concern affecting the survival of unicompartmental knee replacement in patients younger than 50.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 242 - 242
1 Jul 2008
PARRATTE S ARGENSON J FLECHER X AUBANIAC J
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Purpose of the study: Malposition of the acetabular implant of a total hip arthroplasty can provoke dislocation, limited joint movement, and early wear. The purpose of this prospective randomized study was to assess the efficacy of a image-free navigation system to achieve correct acetabular position for total hip arthroplasty.

Material and methods: The navigation software for the acetabular component used intraoperative anatomic acquisition. The prospective randomized study included two groups of 20 patients. In the first group, the acetabular implant was inserted using the computer-assisted system and in the second using the conventional method. The same operator performed all procedures via an anterolateral approach and using the same non-cemented hemispheric cup. The postoperative assessment was performed by an independent investigator who noted the cup inclination on the standard ap view and cup anteversion on the computed tomography; then using a dedicated system for 3D reconstruction, the same values were determined one month after surgery.

Results: Each group included ten men and ten women, mean age 63 years and mean body mass index 24. For the computed-assisted group, mean additional operative time for navigation was 13 minutes (range 8–20 min). The intraopeartive concordance with the surgeons subjective impression was excellent for 12 patients and good for 8. Mean intraoperative values were for the computer-assisted group were: for operative mode: inclination 30° (25–46°), anteversion 14° (0–25°), radiographic mode: inclination 35° (25–47°), anteversion 13° (0–26°), anatomic mode: inclination 36°, anteversion 19° (0–27°). There was no significant difference between the intraoperative and postoperative values for the computer-assisted group. There was no significant difference between the average values between the computer-assisted and conventional groups but the standard deviation was smaller in the computer-assisted group.

Discussion and conclusion: The image-free navigation system enables reliable positioning of the prosthetic cup for total hip arthroplasty and increases the precision of acetabular implantation without increasing significantly operative time. This first step must be integrated into the computerized preoperative planning for total hip arthroplasty. The next step will be to use the navigation system for implanting the femoral component.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 258 - 258
1 Jul 2008
PARRATTE S JACQUOT N PELEGRI C TROJANI C BOILEAU P
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Purpose of the study: Arthroscopic reinsertion of SLAP lesions is the most commonly used approach. Tenodesis of the long biceps could be proposed as an alternative to reinsertion. The purpose of our study was to report the results of tenodesis and reinsertions for the treatment of type II SLAP lesions.

Material and methods: This was a consecutive monocentric comparative series analyzed retrospectively. Isolated type II SLAP lesions treated arthroscopically were retained for study: 25 cases treated from January 2000 to May 2004. Exclusion criteria were: associated instability, associated cuff tears, history of surgery. The long biceps tendon was reinserted on the glenoid tubercle using two threads mounted on resorbable anchors in ten patients (all men), mean age 27.5 years (range 19–57 years). Tenodesis of the long biceps in the gutter was performed in fifteen patients (six women and nine men), mean age 52.2 years (range 28–64 years). All patients were reviewed by an independent observer.

Results: In the reinsertion group, mean follow-up was 35 months (range 12–57 months). Three patients had revision tenodesis due to persistent pain and three others were disappointed because they were unable to resume their former sport. Four others were very satisfied. The mean Constant score improved from 65 to 83 points. Force was 16 kg in flexion and 5 kg in supination. In the tenodesis group, mean follow-up was 34 months (range 12–56 months). There were no revision procedures in this group. Subjectively, one patient was disappointed (atypical pain), two were satisfied and 12 very satisfied. The mean Constant score improved from 59 to 89 points. Force was 14.5 kg in flexion and 4.8 kg in supination.

Discussion: This series showed that results obtained with reinsertions can be disappointing: three revisions and three disappointed patients among ten procedures. In the tenodesis group, 14 of 15 patients were satisfied or very satisfied. Tenodesis of the long head of the biceps can be considered as an alternative to reinsertion for the treatment of type II SLAP lesions, particularly in older athletes.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 258 - 258
1 Jul 2008
Neyton L PARRATTE S PELEGRI C JACQUOT N BOILEAU P
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Purpose of the study: Depending on the series, fractures of the anteroinferior glenoid labrum have been reported in 3% to 90% of patients with anterior shoulder instability. These fractures disrupt the physiological glenoid concavity and shorten the effective length of the glenoid arch. Indications for treatment depend on the size of the fragment and range from osteosynthesis to resection or suture. We hypothesized that these lesions could be treated arthroscopically (Bankart procedure with fragment suture). The purpose of this work was to analyze clinical and radiological outcome observed in nine patients with anterior instability associated with significant glenoid fracture.

Material and methods: This was a monocentric study of a continuous series of nine glenoid fractures associated with anteromedial dislocation in nine patients (three women and six men), mean age 35.5 years (range 17–75 years). Preoperatively, all of the fractures were considered to involve more than 25% of the glenoid surface. After detaching the capsulolabral lesion with the bony fragment and avivement of the anterior border, the Bankart procedure was performed with anchors and resorbable sutures. The shoulder was strapped for six weeks with passive rehabilitation (pendulum movements) initiated early.

Results: Mean follow-up was 27 months (range 12–48 months). There were no cases of recurrent instability. Seven patients were very satisfied and two were satisfied. Eight patients were able to resume their sports activities at the same level. Apprehension developed in all patients. At last follow-up, joint motion was normal for eight of the nine patients, the Duplay score was 100 for eight patients and 45 for one. All bony lesions healed in an anatomic position (six analyzed with plain x-rays and three with CT scan).

Discussion and conclusion: This short series demonstrates that glenoid fractures can be treated arthroscopically with concomitant treatment of the capsulolabroligament complex in order to reconstruct the glenoid arch, an essential element for restoring shoulder stability. It is thus necessary to identify bony lesions preoperatively to determine the most appropriate therapeutic approach. A long-term follow-up will be useful to assess the rate of recurrent instability and validate this therapeutic option.


The Journal of Bone & Joint Surgery British Volume
Vol. 90-B, Issue 2 | Pages 258 - 263
1 Feb 2008
Parratte S Kilian P Pauly V Champsaur P Argenson JA

We have evaluated in vitro the accuracy of percutaneous and ultrasound registration as measured in terms of errors in rotation and version relative to the bony anterior pelvic plane in computer-assisted total hip replacement, and analysed the intra- and inter-observer reliability of manual or ultrasound registration.

Four clinicians were asked to perform registration of the landmarks of the anterior pelvic plane on two cadavers. Registration was performed under four different conditions of acquisition. Errors in rotation were not significant. Version errors were significant with percutaneous methods (16.2°; p < 0.001 and 19.25° with surgical draping; p < 0.001), but not with the ultrasound acquisition (6.2°, p = 0.13). Intra-observer repeatability was achieved for all the methods. Inter-observer analysis showed acceptable agreement in the sagittal but not in the frontal plane.

Ultrasound acquisition of the anterior pelvic plane was more reliable in vitro than the cutaneous digitisation currently used.


The Journal of Bone & Joint Surgery British Volume
Vol. 89-B, Issue 12 | Pages 1586 - 1591
1 Dec 2007
Flecher X Parratte S Aubaniac J Argenson J

A clinical and radiological study was conducted on 97 total hip replacements performed for congenital hip dislocation in 79 patients between 1989 and 1998 using a three-dimensional custom-made cementless stem. The mean age at operation was 48 years (17 to 72) and the mean follow-up was for 123 months (83 to 182).

According to the Crowe classification, there were 37 class I, 28 class II, 13 class III and 19 class IV hips. The mean leg lengthening was 25 mm (5 to 58), the mean pre-operative femoral anteversion was 38.6° (2° to 86°) and the mean correction in the prosthetic neck was −23.6° (−71° to 13°). The mean Harris hip score improved from 58 (15 to 84) to 93 (40 to 100) points. A revision was required in six hips (6.2%). The overall survival rate was 89.5% (95% confidence interval 89.2 to 89.8) at 13 years when two hips were at risk.

This custom-made cementless femoral component, which can be accommodated in the abnormal proximal femur and will correct the anteversion and frontal offset, provided good results without recourse to proximal femoral corrective osteotomy.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 82 - 82
1 Mar 2006
Rochwerger A Parratte S Sbihi A Roge F Curvale G
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Introduction. Knee arthrodesis is a limb salvage procedure considered as an alternative to an amputation in case of severely infected total knee arthroplasties, associated with large damage of the extensor mechanism. The techniques are various and the series in the literature not always homogenous. In this study we assessed the results of knee arthrodesis performed with two monolateral external fixators in two perpendicular planes .

Material and methods . This retrospective series of 19 knee arthrodeses was done in 18 patients, which were 65 years old on average. All patients had severe damage on their extensor mechanism associated with an infection of their implant. In all cases the infection was documented and patients were treated by antibiotics during on average 9 months. The first surgical step consisted in a debridement of the knee which was provisionally fixated with the lateral external fixator. The second step consisted in the removal of the infected implant or of the spacer . The bony surfaces were freshened and the anterior external fixator was applied with a compressive effect on the fusion site . Full weight bearing was allowed 45 days after surgery.

Results. Radiological fusion was observed in 17 cases after 4,6 months on average and the external fixators were removed after 8 months on average. Two patients experienced wound healings problems that required additional plastic surgery. Two cases were revised and bone grafting was performed. One patient suffered from malunion at the last follow up ( 7 years in this study).

Discussion. This type of fixation avoids internal fixation in septic conditions. The transquadricipital pins of the anterior fixator are well tolerated. The rigidity of the combination of two monolateral fixators in two perpendicular planes allows quick reloading , which is essential in old patients, often debilitated by numerous procedures.

Conclusion. Arthrodesis is functionally an acceptable alternative to an amputation in these patients. This technique is reliable, has the advantage of avoiding an internal device in an infected knee, of stabilizing the fusion site thanks to the biplanar fixation and of allowing quick weight bearing,.


The Journal of Bone & Joint Surgery British Volume
Vol. 87-B, Issue 9 | Pages 1192 - 1196
1 Sep 2005
Argenson J Ryembault E Flecher X Brassart N Parratte S Aubaniac J

Using radiography and computer tomography (CT) we studied the morphology of 83 hips in 69 Caucasian adults with osteoarthritis secondary to developmental dysplasia of the hip (DDH). A previously published series of 310 hips with primary osteoarthritis was used as a control group. According to the Crowe classification, 33 of the dysplastic hips were graded as class I, 27 as class II and 23 as class III or class IV.

The intramedullary femoral canal had reduced mediolateral and anteroposterior dimensions in all groups compared with the control group. Only in Crowe class II hips was the femoral neck-shaft angle increased. The proximal femur had more anteversion in all the developmental dysplasia of the hip groups, ranging from 2° to 80°. Templated measurement of acetabular dimensions for plain radiography closely matched measurements taken by CT.

The results of our study confirm the observations previously confined to the Japanese population.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 130 - 130
1 Apr 2005
Gravier R Flecher X Parratte S Rapaie P Argenson J
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Purpose: Wrist fractures are often seen in elderly subjects who cannot generally tolerate aggressive fixation of unstable fractures. Percutaneous intra-focal pinning (Kapandji) is usually employed. The purpose of this study was to compare the classical treatment of unstable extra-articular fractures of the lower quarter of the radius with posterior displacement with a modified pinning technique.

Material and methods: This prospective radiological study concerned two groups of randomised patients aged 30 – 70 years who were hospitalised for surgical treatment of Pouteau-Colles fractures. In the first group, all patients were treated by the classical intra-focal technique using one or two dorsal pins and one lateral pin (group K). In the second group, all patients were treated by fixation with one or two infrafocal dorsal pins and a third pin inserted transfocally (group KM). Preoperative care, anaesthesia, and postoperative care (21 days immobilisation, pin removal at 45 days) were the same in both groups. The following anatomic measurements were made on the radiographs at day 1, 21, 45, and last follow-up: radial inclination on the lateral and AP views, bistyloid line.

Results: Group K included 49 patients, mean age 45 years. Group KM included 46 patients, mean age 54 years. There was no statistical difference between groups for age, gender, side, type of fracture. Radial inclination on the AP view was 19.2 (10–27 in group KM and 23.2 (19-30) in group. On the lateral view, radial inclination was 0 (−11 to 20) in group KM and −5.7 (−25 to 2) in group K. The proportion of bistyloid lines considered satisfactory was not different between groups.

Discussion: Infra-focal pinning can have limitations for maintaining reduction to bone healing. The Kapandji technique modified by use of a third transstyloid pin appears to provide better stabilisation of unstable fractures of the lower extremity of the radius, particularly in older subjects who cannot tolerate aggressive surgery. This preliminary study should be completed by a radio-clinical analysis in a larger number of patients to confirm these results.