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The Bone & Joint Journal
Vol. 99-B, Issue 6 | Pages 724 - 731
1 Jun 2017
Mei-Dan O Jewell D Garabekyan T Brockwell J Young DA McBryde CW O’Hara JN

Aims. The aim of this study was to evaluate the long-term clinical and radiographic outcomes of the Birmingham Interlocking Pelvic Osteotomy (BIPO). Patients and Methods. In this prospective study, we report the mid- to long-term clinical outcomes of the first 100 consecutive patients (116 hips; 88 in women, 28 in men) undergoing BIPO, reflecting the surgeon’s learning curve. Failure was defined as conversion to hip arthroplasty. The mean age at operation was 31 years (7 to 57). Three patients (three hips) were lost to follow-up. Results. Survivorship was 76% at ten years and 57% at a mean of 17 years. Younger patients (< 20 years) had the best survivorship (20 hips at risk; 90% at 17 years; 95% confidence interval 65 to 97). Post-operative complications occurred after 12 operations (10.4%) over the duration of the study. Increasing patient age and hip arthritis grade were primary determinants of surgical failure. Conclusion. BIPO provides good to excellent survivorship in appropriately selected patients, with a relatively low rate of complications. Our results are comparable with other established methods of periacetabular osteotomy (PAO), such as the Bernese PAO, even during the surgeon’s initial learning curve. Cite this article: Bone Joint J 2017;99-B:724–31


The Journal of Bone & Joint Surgery British Volume
Vol. 94-B, Issue 3 | Pages 315 - 321
1 Mar 2012
Coulter G Young DA Dalziel RE Shimmin AJ

We report the findings of an independent review of 230 consecutive Birmingham hip resurfacings (BHRs) in 213 patients (230 hips) at a mean follow-up of 10.4 years (9.6 to 11.7). A total of 11 hips underwent revision; six patients (six hips) died from unrelated causes; and 13 patients (16 hips) were lost to follow-up. The survival rate for the whole cohort was 94.5% (95% confidence interval (CI) 90.1 to 96.9). The survival rate in women was 89.1% (95% CI 79.2 to 94.4) and in men was 97.5% (95% CI 92.4 to 99.2). Women were 1.4 times more likely to suffer failure than men. For each millimetre increase in component size there was a 19% lower chance of a failure. The mean Oxford hip score was 45.0 (median 47.0, 28 to 48); mean University of California, Los Angeles activity score was 7.4 (median 8.0, 3 to 9); mean patient satisfaction score was 1.4 (median 1.0, 0 to 9). A total of eight hips had lysis in the femoral neck and two hips had acetabular lysis. One hip had progressive radiological changes around the peg of the femoral component. There was no evidence of progressive neck narrowing between five and ten years. Our results confirm that BHR provides good functional outcome and durability for men, at a mean follow-up of ten years. We are now reluctant to undertake hip resurfacing in women with this implant


The Journal of Bone & Joint Surgery British Volume
Vol. 94-B, Issue 4 | Pages 471 - 476
1 Apr 2012
Holland JP Langton DJ Hashmi M

We present the clinical results and survivorship of consecutive 100 Birmingham Hip Resurfacings in 90 patients at a minimum follow-up of ten years. All procedures were carried out by an independent surgeon who commenced a prospective study in 1998. Patients were assessed clinically using the Western Ontario and McMaster Universities osteoarthritis index, Short-Form 36, Harris hip score and University of California, Los Angeles activity score. Radiological analysis was performed by an independent observer and blood metal ion levels concentrations were measured at ten years post-operatively in 62 patients. The median acetabular component inclination was 46.2° (34° to 59°) and anteversion 11.0° (0° to 30°). The median chromium concentration in the unilateral group was 1.74 (0.41 to 15.23) and for the bilateral group was 2.98 (1.57 to 18.01). The equivalent values for cobalt were 1.67 (0.54 to 20.4) and 1.88 (1.38 to 19.32). In total there were eight failures giving an overall survival at ten years of 92% (95% confidence interval (CI) 86.7 to 97.3). BHR in male patients had an improved survivorship of 94.6% (95% CI 89.4 to 100) compared with females at 84.6% (95% CI 70.7 to 98.5), but this did not reach statistical significance (p = 0.119). Four of the nine BHRs with a bearing diameter of 42 mm failed. The overall results were consistent with data produced from other centres in that the clinical outcome of large male patients was extremely encouraging, whereas the survival of the smaller joints was less satisfactory


The Bone & Joint Journal
Vol. 105-B, Issue 9 | Pages 946 - 952
1 Sep 2023
Dhawan R Young DA Van Eemeren A Shimmin A

Aims. The Birmingham Hip Resurfacing (BHR) arthroplasty has been used as a surgical treatment of coxarthrosis since 1997. We present 20-year results of 234 consecutive BHRs performed in our unit. Methods. Between 1999 and 2001, there were 217 patients: 142 males (65.4%), mean age 52 years (18 to 68) who had 234 implants (17 bilateral). They had patient-reported outcome measures collected, imaging (radiograph and ultrasound), and serum metal ion assessment. Survivorship analysis was performed using Kaplan-Meier estimates. Revision for any cause was considered as an endpoint for the analysis. Results. Mean follow-up was 20.9 years (19.3 to 22.4). Registry data revealed that 19 hips (8.1%) had been revised and 26 patients (12%) had died from causes unrelated to the BHR. Among the remaining 189 hips, 61% were available for clinical follow-up at 20 years (n = 115) and 70% of patients had biochemical follow-up (n = 132). The cumulative implant survival rate at 20 years for male patients was 96.5% (95% confidence interval (CI) 93.5 to 99.6), and for female patients 87% (95% CI 79.7 to 94.9). The difference was statistically significant (p = 0.029). The mean Oxford Hip Score, Hip disability and Osteoarthritis Outcome Score, and Forgotten Joint Score were 45 (29 to 48), 89 (43 to 100), and 84 (19 to 100), respectively. The mean scores for each of the five domains of the EuroQol five-dimension three-level questionnaire were 1.2, 1.0, 1.2, 1.3, and 1.1, and mean overall score 82.6 (50 to 100). Ultrasound showed no pseudotumour. Mean cobalt and chromium levels were 32.1 nmol/l (1 to 374) and 45.5 nmol/l (9 to 408), respectively. Conclusion. This study shows that BHRs provide excellent survivorship and functional outcomes in young male patients. At 20 years, soft-tissue imaging and serum metal ion studies suggest that a metal-on-metal resurfacing implant can be well tolerated in a group of young patients. Cite this article: Bone Joint J 2023;105-B(9):946–952


The Bone & Joint Journal
Vol. 106-B, Issue 6 | Pages 540 - 547
1 Jun 2024
Nandra RS Elnahal WA Mayne A Brash L McBryde CW Treacy RBC

Aims. The Birmingham Hip Resurfacing (BHR) was introduced in 1997 to address the needs of young active patients using a historically proven large-diameter metal-on-metal (MoM) bearing. A single designer surgeon’s consecutive series of 130 patients (144 hips) was previously reported at five and ten years, reporting three and ten failures, respectively. The aim of this study was to extend the follow-up of this original cohort at 25 years. Methods. The study extends the reporting on the first consecutive 144 resurfacing procedures in 130 patients for all indications. All operations were undertaken between August 1997 and May 1998. The mean age at operation was 52.1 years (SD 9.93; 17 to 76), and included 37 female patients (28.5%). Failure was defined as revision of either component for any reason. Kaplan-Meier survival analysis was performed. Routine follow-up with serum metal ion levels, radiographs, and Oxford Hip Scores (OHSs) was undertaken. Results. Overall implant survival was 83.50% (95% confidence interval (CI) 0.79 to 0.90) at 25 years, and the number at risk was 79. Survival in male patients at 25 years was 89.5% (95% CI 0.83 to 0.96) compared to 66.9% for female patients (95% CI 0.51 to 0.83). Ten additional failures occurred in the period of ten to 25 years. These involved an adverse reaction to metal debris in four patients, a periprosthetic femoral neck fracture affecting five patients, and aseptic loosening in one patient. The median chromium levels were 49.50 nmol/l (interquartile range (IQR) 34 to 70), and the median cobalt serum levels were 42 nmol/l (IQR 24.50 to 71.25). The median OHS at last follow-up was 35 (IQR 10 to 48). During the 25-year study period, 29 patients died. Patient survival at 25 years was 75.10% (95% CI 0.67 to 0.83). Conclusion. This study demonstrates that MoM hip resurfacing using the BHR provides a durable alternative to total hip arthroplasty (THA), particularly in younger male patients with osteoarthritis wishing to maintain a high level of function. These results compare favourably to the best results for THAs. Cite this article: Bone Joint J 2024;106-B(6):540–547


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 472 - 473
1 Sep 2009
Nizam I Kohan L Kerr D
Full Access

Birmingham Hip resurfacings have been a popular mode of treatment for younger and more active patients with arthritis of the hip. However the use of hybrid hip arthroplasty system with a Birmingham hip resurfacing cup and modular head with a variety of cemented/uncemented stems is less well described in the literature. We analysed radiographic and clinical outcomes of 99 consecutive hybrid hip arthroplasties performed by a single surgeon between 2000 and 2006. A total of 93 patients (52 females and 41 males) with an average age of 69.9 (47 to 88) and average BMI of 28.8 (18.7 to 140.9) had arthroplasties with a mean follow up of 4.1 Yrs (1 to 6.3 years). 57 right and 42 left hip arthroplasties were performed of which 6 patients had bilateral consecutive hybrid hip arthroplasties. 93 were performed for osteoarthritis, 4 for RA, 5 patients for revision of failed hip resurfacing arthroplasties with #NOF and 1 revision for failed THR. No patients had dislocations and one patient had revision of a resurfacing cup secondary to hip pain due to excessive cup anteversion, no loosening of components were identified at the most recent follow-up and all patients were mobilising well with no complaints of pain. Hip Resurfacing procedures are gaining popularity in the younger individuals with arthrosis of the hip. Some patients who are fairly independent and active fall short of satisfying the criteria for a hip resurfacing and we preferred the option of the Birmingham hip resurfacing cup with a large modular head and a compliment of stems. This metal-on-metal option with large heads would ideally increase stability and reduce wear patterns with the prospect of increasing longevity of total hip arthroplasties


The Journal of Bone & Joint Surgery British Volume
Vol. 90-B, Issue 3 | Pages 319 - 323
1 Mar 2008
Moonot P Singh PJ Cronin MD Kalairajah YE Kavanagh TG Field RE

Hip resurfacing is a bone-conserving procedure with respect to proximal femoral resection, but there is debate in the literature as to whether the same holds true for the acetabulum. We have investigated whether the Birmingham hip resurfacing conserves acetabular bone. Between 1998 and 2005, 500 Birmingham hip resurfacings were performed by two surgeons. Between 1996 and 2005 they undertook 700 primary hip replacements, with an uncemented acetabular component. These patients formed the clinical material to compare acetabular component sizing. The Birmingham hip resurfacing group comprised 350 hips in men and 150 hips in women. The uncemented total hip replacement group comprised 236 hips in men and 464 hips in women. Age- and gender-matched analysis of a cohort of patients for the sizes of the acetabular components required for the two types of replacement was also undertaken. Additionally, an analysis of the sizes of the components used by each surgeon was performed. For age-matched women, the mean outside diameter of the Birmingham hip resurfacing acetabular components was 2.03 mm less than that of the acetabular components in the uncemented total hip replacements (p < 0.0001). In similarly matched men there was no significant difference (p = 0.77). A significant difference was also found between the size of acetabular components used by the two surgeons for Birmingham hip resurfacing for both men (p = 0.0015) and women (p = 0.001). In contrast, no significant difference was found between the size of acetabular components used by the two surgeons for uncemented total hip replacement in either men or women (p = 0.06 and p = 0.14, respectively). This suggests that variations in acetabular preparation also influence acetabular component size in hip resurfacing


The Journal of Bone & Joint Surgery British Volume
Vol. 88-B, Issue 8 | Pages 1110 - 1115
1 Aug 2006
Ong KL Kurtz SM Manley MT Rushton N Mohammed NA Field RE

The effects of the method of fixation and interface conditions on the biomechanics of the femoral component of the Birmingham hip resurfacing arthroplasty were examined using a highly detailed three-dimensional computer model of the hip. Stresses and strains in the proximal femur were compared for the natural femur and for the femur resurfaced with the Birmingham hip resurfacing. A comparison of cemented versus uncemented fixation showed no advantage of either with regard to bone loading. When the Birmingham hip resurfacing femoral component was fixed to bone, proximal femoral stresses and strains were non-physiological. Bone resorption was predicted in the inferomedial and superolateral bone within the Birmingham hip resurfacing shell. Resorption was limited to the superolateral region when the stem was not fixed. The increased bone strain observed adjacent to the distal stem should stimulate an increase in bone density at that location. The remodelling of bone seen during revision of failed Birmingham hip resurfacing implants appears to be consistent with the predictions of our finite element analysis


The Bone & Joint Journal
Vol. 106-B, Issue 3 Supple A | Pages 44 - 50
1 Mar 2024
Engh, Jr CA Bhal V Hopper, Jr RH

Aims. The first aim of this study was to evaluate whether preoperative renal function is associated with postoperative changes in whole blood levels of metal ions in patients who have undergone a Birmingham Hip Resurfacing (BHR) arthroplasty with a metal-on-metal bearing. The second aim was to evaluate whether exposure to increased cobalt (Co) and chromium (Cr) levels for ten years adversely affected renal function. Methods. As part of a multicentre, prospective post-approval study, whole blood samples were sent to a single specialized laboratory to determine Co and Cr levels, and the estimated glomerular filtration rate (eGFR). The study included patients with 117 unrevised unilateral BHRs. There were 36 females (31%). The mean age of the patients at the time of surgery of 51.3 years (SD 6.5), and they all had preoperative one-, four-, five-, and ten-year laboratory data. The mean follow-up was 10.1 years (SD 0.2). Results. Median Co levels at one year postoperatively increased significantly compared with the preoperative values, by a factor of 9.7, from 0.13 to 1.26 ppb (p < 0.001), and the median Cr levels increased significantly by a factor of 2.5, from 0.60 to 1.50 ppb (p < 0.001). Lower preoperative eGFRs were associated with significantly larger increases in Co at one year compared with the preoperative levels (ρ = -0.26; p = 0.005), but there was no relationship between preoperative eGFRs and changes in Cr at one year (ρ = -0.13; p = 0.153). Metal levels remained relatively constant with the passage of time, with a median ten-year value of 1.12 ppb for Co and 1.29 ppb for Cr. There was no significant relationship between the Co and Cr levels at ten-year follow-up and the change in eGFR from the preoperative level to that at ten years (ρ = -0.02; p = 0.827 for Co; ρ = -0.008; p = 0.933 for Cr). Conclusion. Although patients with lower preoperative eGFRs tended to have larger increases in Co levels at one year, increased metal levels for patients who underwent unilateral BHR did not adversely affect renal function during the first ten postoperative years. Cite this article: Bone Joint J 2024;106-B(3 Supple A):44–50


The Journal of Bone & Joint Surgery British Volume
Vol. 93-B, Issue 1 | Pages 27 - 33
1 Jan 2011
Treacy RBC McBryde CW Shears E Pynsent PB

We report the survival, radiological and functional outcomes of a single surgeon series of his first 144 consecutive Birmingham hip resurfacing procedures (130 patients) at a minimum of ten years. There were ten revisions during this time. Although no patients were lost to follow-up some did not complete the scoring assessment or undergo radiological assessment at ten years. The ten-year survival for male patients was 98.0% (95% confidence interval 95.2 to 100). The ten-year survival for the total cohort with aseptic revision as the endpoint was 95.5% (95% confidence interval 91.8 to 99.0) and including revisions for sepsis was 93.5% (95% confidence interval 89.2 to 97.6). The median modified Oxford hip score at ten years was 4.2% (interquartile range 0 to 19) and the median University of California, Los Angeles score was 7.0 (interquartile range 5.0 to 8.0). This study confirms the midterm reports that metal-on-metal hip resurfacing using the Birmingham Hip provides a durable alternative to total hip replacement, particularly in younger male patients wishing to maintain a high level of function, with low risk of revision for at least ten years


The Bone & Joint Journal
Vol. 101-B, Issue 11 | Pages 1431 - 1437
1 Nov 2019
Harrison-Brown M Scholes C Ebrahimi M Field C Cordingley R Kerr D Farah S Kohan L

Aims. It is not known whether change in patient-reported outcome measures (PROMs) over time can be predicted by factors present at surgery, or early follow-up. The aim of this study was to identify factors associated with changes in PROM status between two-year evaluation and medium-term follow-up. Patients and Methods. Patients undergoing Birmingham Hip Resurfacing completed the Veteran’s Rand 36 (VR-36), modified Harris Hip Score (mHHS), Tegner Activity Score, and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) at two years and a minimum of three years. A change in score was assessed against minimal clinically important difference (MCID) and patient-acceptable symptom state (PASS) thresholds. Binary logistic regression was used to assess the relationship between patient factors and deterioration in PASS status between follow-ups. Results. Overall, 18% of patients reported reductions in mHHS total score exceeding MCID, and 21% reported similar reductions for WOMAC function scores. Nonetheless, almost all patients remained above PASS thresholds for WOMAC function (98%) and mHHS (93%). Overall, 66% of patients with mHHS scores < PASS at two years reported scores > PASS at latest follow-up. Conversely, 6% of patients deteriorated from > PASS to < PASS between follow-ups. Multivariable modelling indicated body mass index (BMI) > 27 kg/m. 2. , VR-36 Physical Component Score (PCS) < 51, VR-36 Mental Component Score (MCS) > 55, mHHS < 84 at two years, female sex, and bone graft use predicted these deteriorating patients with 79% accuracy and an area under the curve (AUC) of 0.84. Conclusion. Due to largely acceptable results at a later follow-up, extensive monitoring of multiple PROMs is not recommended for Birmingham Hip Resurfacing patients unless they report borderline or unacceptable hip function at two years, are female, are overweight, or received a bone graft during surgery. Cite this article: Bone Joint J 2019;101-B:1431–1437


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_12 | Pages 33 - 33
23 Jun 2023
Engh CA Bhal V Hopper RH
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When the Birmingham Hip Resurfacing (BHR) metal-on-metal implant system was approved by the United States Food and Drug Administration in 2006, a multicenter, prospective, post-approval study (PAS) was required. This study uses data from the PAS to investigate metal level and glomerular filtration rate (GFR) trends over the first decade in vivo. Between October 2006 and March 2011, 290 primary BHR procedures were performed among 262 patients at 5 sites. Whole blood samples were sent to a single specialized laboratory to determine GFR, cobalt (Co) and chromium (Cr) levels. The population for this study consists of 117 unrevised unilateral patients with a mean age at surgery of 51.3±6.5 years who had pre-operative, 1-year, 4-year, 5-year and 10-year laboratory data. The mean follow-up for these patients that included 36 females was 10.1±0.2 years. Median metal levels at 1-year increased relative to pre-operative values for Co (by a factor of 9.7 from 0.13 to 1.26 ppb, p<0.001) and Cr (by a factor of 2.5 from 0. 60 to 1.50 ppb, p<0.001). Metal levels subsequently remained relatively constant over time with a median 10-year value of 1.12 ppb for Co and 1.29 ppb for Cr. Based on 585 blood samples from all 117 patients, there was no relationship between GFR and Co (. →. =−0.06, p=0.14) or Cr (. →. =0.05, p=0.27) levels. However, lower pre-operative GFR values were associated with larger increases in Co at 1-year relative to the pre-operative level (. →. =−0.26, p=0.005). There was no relationship between pre-operative GFR values and changes in Cr at 1 year (. →. =−0.13, p=0.15). Through the first decade in vivo, elevated whole blood metal levels for unilateral BHR patients do not appear to adversely affect GFR. However, patients with lower pre-operative GFR values tend to have larger increases in their Co level at 1-year


The Journal of Bone & Joint Surgery British Volume
Vol. 90-B, Issue 9 | Pages 1137 - 1142
1 Sep 2008
Heilpern GNA Shah NN Fordyce MJF

We report the outcome at a minimum of five years of 110 consecutive metal-on-metal Birmingham Hip Resurfacing arthroplasties in 98 patients. The procedures were performed between October 1999 and June 2002 by one surgeon. All patients were followed up clinically and radiologically. The mean follow-up was 71 months (60 to 93). Revision of either component was defined as failure. The mean Harris Hip score at follow-up was 96.4 (53 to 100). The mean Oxford hip score was 41.9 (16 to 57) pre-operatively and 15.4 (12 to 49) post-operatively (p < 0.001). The mean University of California Los Angeles activity score was 3.91 (1 to 10) pre-operatively and 7.5 (4 to 10) post-operatively (p < 0.001). There were four failures giving a survival at five years of 96.3% (95% confidence interval 92.8 to 99.8). When applying a new method to estimate narrowing of the femoral neck we identified a 10% thinning of the femoral neck in 16 hips (14.5%), but the relevance of this finding to the long-term outcome remains unclear. These good medium-term results from an independent centre confirm the original data from Birmingham


The Bone & Joint Journal
Vol. 101-B, Issue 11 | Pages 1423 - 1430
1 Nov 2019
Wiik AV Lambkin R Cobb JP

Aims. The aim of this study was to assess the functional gain achieved following hip resurfacing arthroplasty (HRA). Patients and Methods. A total of 28 patients (23 male, five female; mean age, 56 years (25 to 73)) awaiting Birmingham HRA volunteered for this prospective gait study, with an age-matched control group of 26 healthy adults (16 male, ten female; mean age, 56 years (33 to 84)). The Oxford Hip Score (OHS) and gait analysis using an instrumented treadmill were used preoperatively and more than two years postoperatively to measure the functional change attributable to the intervention. Results. The mean OHS improved significantly from 27 to 46 points (p < 0.001) at a mean of 29 months (12 to 60) after HRA. The mean metal ion levels at a mean 32 months (13 to 60) postoperatively were 1.71 (0.77 to 4.83) µg/l (ppb) and 1.77 (0.68 to 4.16) µg/l (ppb) for cobalt and chromium, respectively. When compared with healthy controls, preoperative patients overloaded the contralateral good hip, limping significantly. After HRA, patients walked at high speeds, with symmetrical gait, statistically indistinguishable from healthy controls over almost all characteristics. The control group could only be distinguished by an increased push-off force at higher speeds, which may reflect the operative approach. Conclusion. Patients undergoing HRA improved their preoperative gait pattern of a significant limp to a symmetrical gait at high speeds and on inclines, almost indistinguishable from normal controls. HRA with an approved device offers substantial functional gains, almost indistinguishable from healthy controls. Cite this article: Bone Joint J 2019;101-B:1423–1430


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 248 - 248
1 May 2006
Shah MG Singer MG
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Femoral neck fracture is a recognised complication of Birmingham Hip Resurfacing. But stress fracture is uncommon. Femoral neck stress fractures are one of the most difficult problems to diagnose. The pain associated with a femoral neck stress fracture often is localized poorly and may be referred to the thigh or back. We present a young fit gentleman who underwent Birmingham Hip resurfacing for Osteoarthritis Hip. He underwent Birmingham Hip Resurfacing Right side with satisfactory post-operative x-rays and progress. He presented for the Left side Birmingham Hip Resurfacing. X-rays revealed a stress fracture through the femoral neck. Patient was asymptomatic and refused any surgical intervention. Patient successfully underwent Birmingham Hip Resurfacing Left side. The Right stress fracture neck of femur healed in varus without any further complications. The patient is asymptomatic after 30 months of diagnosis. We conclude that expectant treatment has role in asymptomatic stress fracture following Birmingham Hip resurfacing


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_4 | Pages 24 - 24
1 Apr 2022
Partridge T Osborne S Marsh M Holland J
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We present a consecutive case cohort of the first 100 Birmingham Hip Resurfacing (BHR)'s in 90 patients with a minimum follow up of 20 years. All procedures were performed by a single surgeon having commenced the study in 1998. The original cohort included 68 males with 75 hips (7 bilateral) and 22 females with 25 hips (3 bilateral). The mean age at index procedure was 52. Patients were recalled to review in clinic as per Medicines and Healthcare products Regulatory Agency guidelines with x-rays, metal ions and Harris Hip Scores recorded. After a minimum of 20 year follow-up review the known overall revision rate is 11%. 11 have died and 7 have been lost to review. In males the known revision rate is 4/75 (5%), 3 of which were due to early fractures and 1 revision for infection at 5 years. The known revision rate in females is 7/25 (28%) of which 6 were due to adverse reactions to metal debris; 3 at 7–8 yrs, 1 at 15 yrs, 2 at 18 years, and 1 at 2 months for avascular necrosis. The mean 20 year metal ions results were cobalt 36.6 nmol/l (range 7.4–232.1) and chromium 32.1 nmol/l (range 6–120.8). The mean Harris hip score was 88.5 (range 38.6–99.8). This case series with 20 years follow-up demonstrates excellent long term survival of the BHRs further to registry BHR data and similar to THR for same age recipients. Applying today's strict criteria for patient selection would likely improve survival rate further. BHR has not demonstrated the catastrophic revision rates associated with some metal-on-metal resurfacing and remains a safe option for those who meet the criteria


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_12 | Pages 22 - 22
1 Dec 2022
Werle J Kearns S Bourget-Murray J Johnston K
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A concern of metal on metal hip resurfacing arthroplasty is long term exposure to Cobalt (Co) and Chromium (CR) wear debris from the bearing. This study compares whole blood metal ion levels from patients drawn at one-year following Birmingham Hip Resurfacing (BHR) to levels taken at a minimum 10-year follow-up. A retrospective chart review was conducted to identify all patients who underwent a BHR for osteoarthritis with a minimum 10-year follow-up. Whole blood metal ion levels were drawn at final follow-up in June 2019. These results were compared to values from patients with one-year metal ion levels. Of the 211 patients who received a BHR, 71 patients (54 males and 17 females) had long term metal ion levels assessed (mean follow-up 12.7 +/− 1.4 years). The mean Co and Cr levels for patients with unilateral BHRs (43 males and 13 females) were 3.12 ± 6.31 ug/L and 2.62 ± 2.69 ug/L, respectively, and 2.78 ± 1.02 ug/L and 1.83 ± 0.65 ug/L for patients with bilateral BHRs (11 males and 4 females). Thirty-five patients (27 male and 8 female) had metal-ion levels tested at one-year postoperatively. The mean changes in Co and Cr levels were 2.29 ug/l (p = 0.0919) and 0.57 (p = 0.1612), respectively, at one year compared to long-term. These changes were not statistically significant. This study reveals that whole blood metal ion levels do not change significantly when comparing one-year and ten-year Co and Cr levels. These ion levels appear to reach a steady state at one year. Our results also suggest that regular metal-ion testing as per current Medicines and Healthcare products Regulatory Agency (MHRA) guidelines may be impractical for asymptomatic patients. Metal-ion levels, in and of themselves, may in fact possess little utility in determining the risk of failure and should be paired with radiographic and clinical findings to determine the need for revision


The Journal of Bone & Joint Surgery British Volume
Vol. 89-B, Issue 11 | Pages 1431 - 1438
1 Nov 2007
Hing CB Back DL Bailey M Young DA Dalziel RE Shimmin AJ

We report an independent prospective review of the first 230 Birmingham hip resurfacings in 212 patients at a mean follow-up of five years (4 to 6). Two patients, one with a loose acetabular component and the other with suspected avascular necrosis of the femoral head, underwent revision. There were two deaths from unrelated causes and one patient was lost to follow-up. The survivorship with the worst-case scenario was 97.8% (95% confidence interval 95.8 to 99.5). The mean Harris hip score improved significantly (paired t-test, p < 0.05) from 62.54 (8 to 92) pre-operatively to 97.7 (61 to 100) at a mean of three years (2.1 to 4.3), then deteriorated slightly to a mean of 95.2 (47 to 100) at a mean of five years. The mean flexion improved from 91.5° (25° to 140°) to 110.4° (80° to 145°) at a mean of three years with no further improvement at five years (111.2°; 70° to 160°). On radiological review at five years, one patient had a progressive lucent line around the acetabular component and six had progressive lucent lines around the femoral component. A total of 18 femoral components (8%) had migrated into varus and those with lucent lines present migrated a mean of 3.8° (1.02° to 6.54°) more than the rest. Superolateral notching of the femoral neck and reactive sclerosis at the tip of the peg of the femoral component were associated with the presence of lucent lines (chi-squared test, p < 0.05), but not with migration of the femoral component, and are of unknown significance. Our results with the Birmingham hip resurfacing continue to be satisfactory at a mean follow-up of five years


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 205 - 205
1 May 2009
Chari R Aweid A Bloomfield M
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Purpose: To find the incidence of Periprosthitic fracture following Birmingham Hip Resurfacing over the age of 65 yrs – in Ashford & St. Peters Hospitals. Method: We have done an audit to study the total number of patients who had Femoral neck fractures following Birmingham Hip Resurfacing, comparing them with the incidence of Femoral neck fracture in the age group of 65 yrs & above, from the period of March 2000 to January 2006 in Ashford & St. Peters Hospitals (NHS & Private). Between March 2000 and January 2006, 327 Birmingham hips were inserted by 8 surgeons. Fracture of the neck of the femur occurred in 5 patients, an incidence of 1.53%. Results:. 1 Intra op fracture & 4 post op fractures. Out of the total number of patients, 131 were above the age of 65years, with mean age of 68.80 years & a range of 65–77 years. No Femoral neck fractures were found in this age group. Conclusion: Incidence of Femoral neck fracture is NIL in the age group of 65 yrs & above compared to 1.53% over all


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXV | Pages 5 - 5
1 Jul 2012
Jewell D McBryde C O'Hara J
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Purpose of study. This study is to determine the survival and outcomes of the Birmingham Interlocking Triple Pelvic Osteotomy. A dysplastic hip predisposes to early arthritis. The Triple Pelvic Osteotomy (TPO) is a joint-preserving option for the treatment of young adults with hip dysplasia. The long term success of the procedure is not known. Patients and methods. The senior author has been performing Birmingham Interlocking Triple Pelvic Osteotomies for 18 years. The outcomes of the first 100 patients (117 TPOs) were reviewed using postal questionnaires, telephone interviews and radiograph review. The primary outcome measure of the study was the Kaplan—Meier survival curve for the TPO. Hip replacement or resurfacing were taken as failure points. The Oxford Hip Score (OHS) and University of California, Los Angeles (UCLA) score were used as secondary outcome measures for the surviving osteotomies. The pre-and post-operative acetabular index and centre-edge angles were measured from surviving radiographs. Results. Follow-up was 93% for survivorship. The mean age at operation was 31 years (range of 7 to 57 years). The mean pre- and post-operative centre-edge angles were 19°and 50° and acetabular indices were 23° and 2°. The Kaplan-Meier survival curve demonstrates that the 10, 15 and 18-year survival rates are 76%, 57% and 50% respectively. Survival was 89% if the osteotomy was performed before 20 years of age. The median UCLA score was five (inter-quartile range three to seven). Median OHS was 41 (inter-quartile range 24 to 46). The UCLA and OHSs show that those with surviving osteotomies tend to have good hip function. Conclusions. The Birmingham Interlocking Pelvic Osteotomy provides a valuable tool to preserve dysplastic hip function and delay arthroplasty surgery, particularly in the younger patient. It is best performed early before arthritis sets in


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_II | Pages 158 - 158
1 Feb 2003
Hashmi M Burton M Holland J Reddy V
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To review the early functional results of Birmingham hip resurfacing. First 116 hips (98 patients), a cohort of consecutive patients prospectively underwent BHR in a single arthroplasty Surgeon’s practice in a University Hospital outside Birmingham. Inclusion criteria fit and active patients. 98 patients mean age 50 years (range 19–67). Pathology OA 85%, Perthes 7%, DDH 4.7% & SUFE 2%. Mean follow-up 30 months (range 12–45). Scoring systems used were Harris hip score (HHS), WOMAC & SF36. HHS: mean pre-arthroplasty 47 (range 10–73), one year 99 (n=57), at 2 years 97.3 (n=26) and at third year 100 (n=3), statistically significant improvement (P=0.001). WOMAC: pain: pre-op score 18.8, at 1 year 5.6 and second year 5.7. Stiffness: pre-op 8.5, 1 year 2.7 & 2. nd. year 2.7. Physical: 49.3, 1 year 23.4 & 2. nd. year 22.6. This shows a statistically significant improvement in pain score (p=0.025) and physical function score (p=0.025). SF-36 one-year post op, when analysed against an age/sex match control group normal values using a 2 tailed ‘t’ Test, seven of the eight domains showed no statistical significance. Only the Social Functioning domain showed a statistically significant result (p=0.011). One fracture following a fall (patient had deep cysts in proximal head now such patients are not offered BHR), one dislocation following RTA and one AVN in a 50 years old post menopausal lady. Birmingham hip resurfacing can provide excellent level of activity and patient satisfaction. A long-term study is needed to evaluate the long-term benefit and survivorship


The Journal of Bone & Joint Surgery British Volume
Vol. 92-B, Issue 10 | Pages 1344 - 1350
1 Oct 2010
Carrothers AD Gilbert RE Jaiswal A Richardson JB

Despite the increasing interest and subsequent published literature on hip resurfacing arthroplasty, little is known about the prevalence of its complications and in particular the less common modes of failure. The aim of this study was to identify the prevalence of failure of hip resurfacing arthroplasty and to analyse the reasons for it. From a multi-surgeon series (141 surgeons) of 5000 Birmingham hip resurfacings we have analysed the modes, prevalence, gender differences and times to failure of any hip requiring revision. To date 182 hips have been revised (3.6%). The most common cause for revision was a fracture of the neck of the femur (54 hips, prevalence 1.1%), followed by loosening of the acetabular component (32 hips, 0.6%), collapse of the femoral head/avascular necrosis (30 hips, 0.6%), loosening of the femoral component (19 hips, 0.4%), infection (17 hips, 0.3%), pain with aseptic lymphocytic vascular and associated lesions (ALVAL)/metallosis (15 hips, 0.3%), loosening of both components (five hips, 0.1%), dislocation (five hips, 0.1%) and malposition of the acetabular component (three hips, 0.1%). In two cases the cause of failure was unknown. Comparing men with women, we found the prevalence of revision to be significantly higher in women (women = 5.7%; men = 2.6%, p < 0.001). When analysing the individual modes of failure women had significantly more revisions for loosening of the acetabular component, dislocation, infection and pain/ALVAL/metallosis (p < 0.001, p = 0.004, p = 0.008, p = 0.01 respectively). The mean time to failure was 2.9 years (0.003 to 11.0) for all causes, with revision for fracture of the neck of the femur occurring earlier than other causes (mean 1.5 years, 0.02 to 11.0). There was a significantly shorter time to failure in men (mean 2.1 years, 0.4 to 8.7) compared with women (mean 3.6 years, 0.003 to 11.0) (p < 0.001)


The Journal of Bone & Joint Surgery British Volume
Vol. 91-B, Issue 8 | Pages 1025 - 1030
1 Aug 2009
Ollivere B Darrah C Barker T Nolan J Porteous MJ

The rate and mode of early failure in 463 Birmingham hip resurfacings in a two-centre, multisurgeon series were examined. Of the 463 patients two have died and three were lost to follow-up. The mean radiological and clinical follow-up was for 43 months (6 to 90). We have revised 13 resurfacings (2.8%) including seven for pain, three for fracture, two for dislocation and another for sepsis. Of these, nine had macroscopic and histological evidence of metallosis. The survival at five years was 95.8% (95% confidence interval (CI) 94.1 to 96.8) for revision for all causes and 96.9% (95% CI 95.5 to 98.3) for metallosis. The rate of metallosis related revision was 3.1% at five years. Risk factors for metallosis were female gender, a small femoral component, a high abduction angle and obesity. We do not advocate the use of the Birmingham Hip resurfacing procedure in patients with these risk factors


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_11 | Pages 23 - 23
1 Jun 2016
Singh S
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Introduction. In the early 2000s hip resurfacing became an established bone conserving hip arthroplasty option particularly for the fit and active patient cohort. The performance of second-generation metal-on-metal bearings had led to the reintroduction of hip resurfacing. The Birmingham Hip resurfacing (BHR) was introduced in 1997. This was followed by a number of different designs of the hip resurfacing. The Durom hip resurfacing was introduced in 2001. These two designs had different metallurgical properties, design parameters particularly clearance and different implantation techniques. Data from joint registries show that both prosthesis perform well. Objectives. Our objective was to perform a retrospective survival analysis comparing the Birmingham to the Durom hip resurfacing and analyse the mode of failures of the cases revised. Methods. Data was collected prospectively but analysed retrospectively. The two cohorts comprised patients treated by two senior surgeons at different units. The follow up range was 1 to 14 years with a mean of 10 years. The end-point was revision for any cause. However this was further substratified. Results. The outcome of all patients was known. The two cohorts exhibited no significant difference in demographics. No failures in either cohort were attributed to adverse reaction to metal debris. Revision for any cause was analysed by plotting Kaplan-Meier Survival curves. The Durom cohort (n=273) had 5 deaths and 9 revisions. The Birmingham cohort (n=567) had 5 deaths and 22 revisions. The Kaplan-Meier survival curves for the two resurfacing designs were different. The Durom cohort demonstrated a concave curve with more early failures. This was contrary to the BHR's convex curve with higher incidence of late failures. We analysed the data by substratifying into failure of femoral or acetabular component and neck fractures. Conclusions. The Kaplan-Meier survival analysis demonstrates that the Durom hip resurfacings had a higher rate of early failure. However extrapolation of the curves suggests that the Durom may have a superior long term survival compared to the BHR. We postulate that this may be due to the femoral implantation technique with less late failures in Duroms and an apparent acceleration of failures in BHR cohort around the ten year stage. Joint registry data also reflect this pattern


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 272 - 273
1 May 2006
Aweid AMS
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The purpose of this study is to show our experience with Birmingham Hip Resurfacing which we think it is a procedure that will play a big role in hip replacement surgery, especially for young people. Methods:. Operative Records from the Theatre Registrar Book, Implant register Book and the theatre computer records. Other similar studies from other Hospitals. Birmingham Hip Resurfacing – Ashford and St. Peter’s Hospitals Experience for the period March 2000 to January 2004. The total number of cases done for the period: 290. The number of patients: 277. Male: 160. Female: 130. Right Hip: 145. Left Hip: 120. Side not recorded: 25. Both sides done: 13. Primary cases: 286. Revisions: 4. The youngest male done aged: 25 years. The youngest female done aged: 33 years. The oldest male done aged: 75 years. The oldest female done aged: 72 years. Mean age: 56.5 years. Conclusion: Birmingham Metal on Metal Resurfacing started by Mr. Derek McMinn at about 13 years ago. Our results and results world-wide are encouraging. The failure rate of THR in young patients is very high, and the revision is difficult and requires a major reconstructive operation. Therefore BHR is a good alternative in our opinion


The Journal of Bone & Joint Surgery British Volume
Vol. 87-B, Issue 3 | Pages 324 - 329
1 Mar 2005
Back DL Dalziel R Young D Shimmin A

We describe the experience with the first consecutive 230 Birmingham hip resurfacings at our centre. At a mean follow-up of three years (25 to 52 months) survivorship was 99.14% with revision in one patient for a loose acetabular component and one death from unrelated causes. One patient developed a fracture of the femoral neck at six weeks which united unremarkably after a period of non-weight-bearing. The Harris hip score improved from a mean of 62.54 (8 to 92) to 97.74 (61 to 100). The mean flexion improved from 91.52° (25 to 140) to 110.41° (80 to 145). Most patients (97%) considered the outcome to be good or excellent. Our preliminary experience with this implant is encouraging and the results are superior to the earlier generation of resurfacings for the same length of follow-up


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_III | Pages 251 - 251
1 Nov 2002
Bose V
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Modern Metal on Metal hip resurfacing originated from Birmingham in the early 1990’s and is now well estabilished in the U.K. This procdure is gaining acceptance in other parts of the world and is now being performed in many countries in the Asia Pacific region including Australia and India.The demographics of the patient population with hip arthritis in south Asia and western europe is very contrasting. Primary osteoarthritis of the hip is virtually non-existent in the Indian subcontinent wheras it is by far the commonest hip disorder in Europe.Sixty nine percent of patients had primary osteoarthritis as the presenting pathology in the pilot series of metal on metal hip resurfacings from Birmingham. Most patiens in India with hip arthritis are very young and have developed secondary degenerative in the joint due to other specific causes. Thus procedures like the Birminham hip resurfacing which addresses the difficult problem of hip arthritis in the young active adult have a greater role to play in this


The Bone & Joint Journal
Vol. 96-B, Issue 10 | Pages 1298 - 1306
1 Oct 2014
Daniel J Pradhan C Ziaee H Pynsent PB McMinn DJW

We report a 12- to 15-year implant survival assessment of a prospective single-surgeon series of Birmingham Hip Resurfacings (BHRs). The earliest 1000 consecutive BHRs including 288 women (335 hips) and 598 men (665 hips) of all ages and diagnoses with no exclusions were prospectively followed-up with postal questionnaires, of whom the first 402 BHRs (350 patients) also had clinical and radiological review. Mean follow-up was 13.7 years (12.3 to 15.3). In total, 59 patients (68 hips) died 0.7 to 12.6 years following surgery from unrelated causes. There were 38 revisions, 0.1 to 13.9 years (median 8.7) following operation, including 17 femoral failures (1.7%) and seven each of infections, soft-tissue reactions and other causes. With revision for any reason as the end-point Kaplan–Meier survival analysis showed 97.4% (95% confidence interval (CI) 96.9 to 97.9) and 95.8% (95% CI 95.1 to 96.5) survival at ten and 15 years, respectively. Radiological assessment showed 11 (3.5%) femoral and 13 (4.1%) acetabular radiolucencies which were not deemed failures and one radiological femoral failure (0.3%). . Our study shows that the performance of the BHR continues to be good at 12- to 15-year follow-up. Men have better implant survival (98.0%; 95% CI 97.4 to 98.6) at 15 years than women (91.5%; 95% CI 89.8 to 93.2), and women < 60 years (90.5%; 95% CI 88.3 to 92.7) fare worse than others. Hip dysplasia and osteonecrosis are risk factors for failure. Patients under 50 years with osteoarthritis fare best (99.4%; 95% CI 98.8 to 100 survival at 15 years), with no failures in men in this group. Cite this article: Bone Joint J 2014;96-B:1298–1306


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 552 - 553
1 Aug 2008
Lee SM Kinbrum A Vassiliou K Kamali A Unsworth A
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Introduction: The Birmingham Hip Resurfacing (BHR) system comprises both a BHR femoral head and a large modular femoral head for use should a total hip replacement be required. The modular femoral head has identical material chemistry, microstructure, spherical form, and surface roughness of the bearing surfaces of resurfacing femoral head and both BHR and THR devices share the same acetabular components. Hence, if the femoral component of a BHR needs revision surgery, the Birmingham hip system provides the potential of converting it to a THR without the need to also revise the well fixed cup. Although it stands to reason that the wear behaviour of the BHR and Birmingham THR will be similar, it is important to investigate the wear behaviour of new THR modular heads against worn BHR cups, representing revision of BHR to Birmingham THR without cup revision. The aim of this study is to assess the viability of the femoral component revision for BHR devices whilst leaving the acetabular components in situ in the pelvis. Materials and Methods: The wear and friction tests were conducted with pristine modular heads paired with BHR cups which had already undergone 5 million cycles (Mc) of wear in a hip simulator against BHR heads. Results and Discussions: The average wear rate of the new Birmingham THR modular heads against worn cups was 0.42 mm. 3. /Mc whilst the new BHR heads against new cups generated wear rate of 0.67 mm. 3. /Mc. Supported by the friction test results, it indicated that the new femoral heads paired with worn cup did not negatively affect the substantial amount of fluid-film lubrication that had developed over the course of the original test. Therefore, it is acceptable to use new femoral heads against worn cups, if the cups are not damaged, well fixed and correctly orientated


The Journal of Bone & Joint Surgery British Volume
Vol. 93-B, Issue 9 | Pages 1169 - 1177
1 Sep 2011
Underwood R Matthies A Cann P Skinner JA Hart AJ

The Articular Surface Replacement (ASR) hip resurfacing arthroplasty has a failure rate of 12.0% at five years, compared with 4.3% for the Birmingham Hip Resurfacing (BHR). We analysed 66 ASR and 64 BHR explanted metal-on-metal hip replacements with the aim of understanding their mechanisms of failure. We measured the linear wear rates of the acetabular and femoral components and analysed the clinical cause of failure, pre-revision blood metal ion levels and orientation of the acetabular component. There was no significant difference in metal ion levels (chromium, p = 0.82; cobalt, p = 0.40) or head wear rate (p = 0.14) between the two groups. The ASR had a significantly increased rate of wear of the acetabular component (p = 0.03) and a significantly increased occurrence of edge loading (p < 0.005), which can be attributed to differences in design between the ASR and BHR. The effects of differences in design on the in vivo wear rates are discussed: these may provide an explanation as to why the ASR is more sensitive to suboptimal positioning than the BHR


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 57 - 58
1 Mar 2006
Forrest N Ashcroft Murray D
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Introduction: Femoral neck failure due to avascular necrosis (AVN) is one of the most significant complications following resurfacing hip arthroplasty. It is likely that the surgical approach is one of the factors influenc-ing the development of AVN. Positron emission tomography (PET) is the only form of imaging that allows visualisation of bone metabolic activity deep to a metal surface. Objectives: To establish the reliability and accuracy of PET using fluorine-18 to evaluate viability of the femoral head and neck after resurfacing hip arthroplasty. To assess the viability of ten proximal femora after Birmingham resurfacing hip arthroplasty via a modified lateral approach. Design: A convenience case series of ten patients taken from the first fifteen from one orthopaedic surgeon’s experience of Birmingham resurfacing hip arthroplasty. Setting: The PET unit of a major urban teaching hospital with a large academic orthopaedic department. Participants: Patients that had undergone unilateral Birmingham resurfacing hip arthroplasty via a modified lateral approach were asked to volunteer for the study. The main criterion for inclusion was ease of attendance for imaging. Intervention: Participants were given a single intravenous dose of 250MBq fluorine-18. After a period of 40 minutes uptake time, PET images of adjacent, sequential 10cm transverse sections including both acetabulae and proximal femora were obtained. Main Outcome Measures: Images were reconstructed to allow relative quantification of uptake between operated and non-operated femoral heads and necks. Results: PET imaging was successful in all subjects and demonstrated activity within the resurfaced femoral heads and femoral necks. No evidence of AVN was found. Conclusions: Static positron emission tomography using fluorine-18 is an accurate and reliable method of assessing femoral head and neck viability after resurfacing hip arthroplasty. No evidence of avascular necrosis was found in this initial series of patients that had undergone Birmingham resurfacing hip arthroplasty via a modified lateral approach


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 552 - 552
1 Aug 2008
Daniel J Pradhan C Ziaee H McMinn DJW
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Introduction: Hip Resurfacing has always been an attractive concept for the treatment of hip arthritis in young patients. Excellent early and medium-term results have been reported with the Birmingham Hip Resurfacing (BHR) device in single and multi-surgeon all-diagnoses and OA series. In the present report we present the results of BHR in inflammatory arthritis. Methods: This is a single-surgeon consecutive series. There were 15 consecutive hips (12 patients) including 2 women (2 hips) with ankylosing spondylitis (AS) operated at a mean age of 41.7 years (range 29.5 to 54.3 years). Fortytwo hips (31 patients) with seronegative or rheumatoid (RA) arthritis treated with a BHR at a mean age of 40 (13 to 64) years and a follow-up of 2 to 9 (mean 5.9) years were also studied. One patient died 5 years later. Revision for any reason was the end-point and unrevised patients were assessed with Oxford hip scores and reviewed clinico-radiologically with AP and lateral radiographs. Results: In the RA group there was one failure from femoral neck fracture two months after operation giving a failure rate of 2.4%. There were no failures in this cohort at a follow-up of 1.8 to 8.8 (mean 4.9) years. As a combined group the failure rate of BHRs in inflammatory arthritis is 1.75% and the cumulative survivorship at 9 years is 98.2% (figure). Discussion: The good results of Birmingham Hip Resurfacing in inflammatory arthritis in this relatively young cohort of patients make this a viable treatment option for these patients. Selection of patients with a reason-able bone quality and adherence to precise operative technique are vital to the success of this procedure


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 407 - 407
1 Sep 2009
Ollivere B Duckett S August A Porteous M
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Introduction: The Birmingham Hip resurfacing was commercially introduced in 1997 and early originating centre series show good functional outcomes. Concerns have been raised over the longevity, functional outcomes and metal ion release from the implants. There are no series of medium term results from an independent district general hospital reported in the literature. We present a prospective series of 100 patients with mean 5 year follow up from a district general hospital. Each patient underwent yearly clinical, hip scoring, and regular radiographic evaluation. Radiographic analysis was undertaken using Harris’, Hodgkinson’s and Amstutz’s criteria, evaluation of component position, neck narrowing and migration using diagnostic PACS workstations with standardised scaled images. Results: Between June 2001 and Feb 2004 100 Birmingham Hip replacements were performed by two consultant surgeons (MP, AA). Mean follow up is 61.2 months (range 38–76 months). Harris hip scores (fig 1) improved from 46 pre-operatively to 90 post-operatively and no significant change over the next five years. There were no revisions in this period. Obese patients (BMI> 30) had a significantly (p< 0.03) lower post operative functional score as compared normal patients. No other factors were significant for outcome. Component position was satisfactory in 93% of cases. Radiographic analysis showed no cups, or stems were definitely loose. Radiolucent lines were present in 8/100 acetabular and 3/100 femoral components, osteolytic lesions were seen in three acetabular components. Mean neck narrowing was 9mm. No patients show any radiographic evidence of avascular necrosis. Conclusion This independent series shows the results of the Birmingham hip resurfacing are reproducible and comparable to those reported in the originating centre. The Birmingham hip resurfacing gives excellent clinical results, and there is no early evidence of radiographic failure. The high rate of neck narrowing gives us cause for concern and we would recommend regular radiographic follow up


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 274 - 274
1 May 2010
Pandit H Steffen R Gundle R Mclardy-Smith P Marks B Beard D Gill H Murray D
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Introduction: Although resurfacing hip replacements are widely used there are few little independent outcome data to support this. The aim of this study was to report the 5 year clinical outcome and 7 year survival of an independent series. Method: 610 Birmingham hip resurfacings were implanted in 532 patients with an average age of 51.8 years (range 16.5–81.6 years) and were followed for between 2 to 8 years; 120 of this series had minimum five year follow-up. Two patients were lost. There were 23 revisions, giving an overall survival of 95% (95% CI 85–99%) at seven years. Fractured neck of femur (n=13) was the most common reason for revision, followed by aseptic loosening (n=4). There were also 3 patients who had failures that were possibly related to metal debris. At a minimum of 5 year follow-up 93% had excellent or good outcome according to the Harris Hip Score. The mean Oxford Hip Score was 16.1 points (SD 7.7) and the mean UCLA activity score was 6.6 points (SD 1.9). There were no patients with definite evidence of radiographic loosening or greater than 10% of neck narrowing. Discussion: The results demonstrate that with the Birmingham Hip Resurfacing, implanted using the extended posterior approach, the five year survival is similar or better to the reported survival rates for cemented and hybrid THR’s in young patients. Conclusions: Considering these patients are young and active these results are good and support the use of resurfacing. However, further study is needed to address the early failures; particularly those related to fracture and metal debris


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 279 - 279
1 Mar 2004
Munawar H Burton M Holland J
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Aims: To review the early results of Birmingham hip resurfacing (BHR). First 116 hips (98 patients). Materials: A cohort of consecutive patients prospectively underwent BHR in a single arthroplasty Surgeonñs practice in a University Hospital out side Birmingham. Inclusion criteria þt and active patients expected to out live conventional THR. 98 patients mean age 50 years (range 19–67). Pathology OA 85%, Perthes 7%, DDH 4.7% & SUFE 2%. Mean follow-up 30 months (range 12–45). Scoring systems used were Harris hip score (HHS), WOMAC & SF 36. Results: All patients under review, no radiological loosening. HHS:Mean pre-arthroplasty score 47 (range 10–73), 1 yr score 99 (n=38), 2yr 97.3 (n=30) at 3yr 100 (n=26) & 4th yr 100 (n=4), this shows a statistically signiþcant improvement (P=0.001). WOMAC: Pain: pre-op score 18.8, at 1 year 5.6 & 2nd year 5.7. Stiffness: pre-op 8.5, 1 year 2.7 & 2nd year 2.7. Physical: 49.3, 1 year 23.4 & 2nd year 22.6. This shows a statistically signiþcant improvement in score (p=0.025) SF-36 Analysed against an age/sex match control group of normal values using a 2 tailed Ôtñ Test, seven of the eight domains showed no statistical signiþcant difference. Complications: One fracture following a fall, 2 AVN & early fractures (patients had deep cysts in proximal head now such patients are not offered BHR), one dislocation following RTA Conclusions: Birmingham hip resurfacing can provide excellent level of activity and patient satisfaction. Careful patient selection is needed. A long-term study is needed to evaluate the long-term beneþt and survivorship


The Journal of Bone & Joint Surgery British Volume
Vol. 90-B, Issue 4 | Pages 436 - 441
1 Apr 2008
Steffen RT Pandit HP Palan J Beard DJ Gundle R McLardy-Smith P Murray DW Gill HS

Few independent studies have reported the outcome of resurfacing arthroplasty of the hip. The aim of this study was to report the five-year clinical outcome and seven-year survival of an independent series. A total of 610 Birmingham Hip Resurfacing arthroplasties were performed in 532 patients with a mean age of 51.8 years (16.5 to 81.6). They were followed for between two and eight years; 107 patients (120 hips) had been followed up for more than five years. Two patients were lost to follow-up. At a minimum of five years’ follow-up, 79 of 85 hips (93%) had an excellent or good outcome according to the Harris hip score. The mean Oxford hip score was 16.1 points (. sd. 7.7) and the mean University of California Los Angeles activity score was 6.6 points (. sd. 1.9). There were no patients with definite radiological evidence of loosening or of narrowing of the femoral neck exceeding 10% of its width. There were 23 revisions (3.8%), giving an overall survival of 95% (95% confidence interval 85.3 to 99.2) at seven years. Fractured neck of femur in 12 hips was the most common indication for revision, followed by aseptic loosening in four. In three hips (three patients) (0.5%), failure was possibly related to metal debris. Considering that these patients are young and active these results are good, and support the use of resurfacing. Further study is needed to address the early failures, particularly those related to fracture and metal debris


The Journal of Bone & Joint Surgery British Volume
Vol. 87-B, Issue 4 | Pages 463 - 464
1 Apr 2005
Shimmin AJ Back D

Between April 1999 and April 2004, 3497 Birmingham hips were inserted by 89 surgeons. Fracture of the neck of the femur occurred in 50 patients, an incidence of 1.46%. Complete data were available for 45 patients in whom the incidence was 1.91% for women and 0.98% for men. The relative risk of fracture for women vs men was 1.94961 and this was statistically significant (p < 0.01). The mean time to fracture was 15.4 weeks. In women the fractures occurred at a mean of 18.5 weeks and were more likely to have been preceded by a pro-dromal phase of pain and limping. In men the mean time to fracture was 13.5 weeks. Significant varus placement of the femoral component, intra-operative notching of the femoral neck and technical problems were common factors in 85% of cases


The Journal of Bone & Joint Surgery British Volume
Vol. 87-B, Issue 2 | Pages 158 - 162
1 Feb 2005
Itayem R Arndt A Nistor L McMinn D Lundberg A

The Birmingham hip resurfacing metal-on-metal arthroplasty was introduced in 1997 and has shown promising short- to mid-term results. We used radiostereophotogrammetric analysis (RSA) to study the stability of 20 resurfacing arthroplasties over a follow-up period of 24 months. Radiological examinations for RSA were performed immediately after surgery and at two, six, 12 and 24 months after operation. Precision and detection of migration thresholds (non-zero movement) were calculated. All the results corresponded well to those found in similar experimental arrangements with standard hip prostheses. Migration of the cup and vertical and mediolateral migration of the head were calculated. The values were low at two years compared with those of earlier studies of cemented femoral components in conventional total hip replacements indicating that there was no evidence of excessive early migration or loosening of the components


The Journal of Bone & Joint Surgery British Volume
Vol. 89-B, Issue 9 | Pages 1140 - 1143
1 Sep 2007
Itayem R Arndt A McMinn DJW Daniel J Lundberg A

The early designs of hip resurfacing implants suffered high rates of early failure, making it impossible to obtain valuable mid-term radiostereophotogrammetric (RSA) results. The metal-on-metal Birmingham Hip Resurfacing arthroplasty has shown promising mid-term results and we present here the first mid-term RSA analysis of a hip resurfacing implant. The analysis was performed in 19 hips at five years post-operatively. The mean acetabular component translation and rotation, and femoral component translation were compared with the previous RSA measurements at two and six months, and one and two years. There was no statistical significance (t-test, p ≤ 0.05) between these consecutive movements, indicating the mid-term stability of the implant


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 25 - 25
1 Mar 2009
Witzleb W Hanisch U Ziegler J Guenther K Rieker C
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Aim: The purpose of this study was to analyze the in-vivo wear rates of Birmingham Hip Resurfacing (BHR, Midland Medical Technologies Ltd., Birmingham, U.K.) explants and to contrast the results to the wear rates of conventional 28 mm metal-on-metal bearings (Metasul, Zimmer GmbH, Winterthur, Switzerland). Methods: The wear rates, measured by a coordinate measuring machine (CMM5, SIP, Geneva, Switzerland), of 6 femoral components and two complete pairings of the BHR retrieved from 8 hips were contrasted to 43 28 mm heads from second generation metal-on-metal bearings (Metasul, Sulzer Orthopaedics Ltd., Winterthur, Switzerland). Results: After 13 months (7 to 24) the BHR femoral heads showed a median volumetric wear rate of 2.9 mm. 3. (interquartile range: 0.8 to 7.1), slightly, but not significantly higher than the investigated 43 28mm Metasul heads (0.8 mm. 3. /year, p = 0.067, 14 months [7 to 24] in-situ). One BHR case with a cup abduction angle of 70° showed a significant higher wear rate of 17.8 mm. 3. All BHR cases showed only small amounts of metallic particle histological and correspondingly, a mild histiocytic tissue response without foreign body granuloma formation. Discussion: During the first two years after surgery the investigated BHR components showed wear rates substantially lower than conventional polyethylene bearings, comparable to Metasul bearings, implanted with very successful clinical results. But whether the wear rates will drop down after the so called running-in period comparable to conventional metal-on-metal bearings and provide young and active patients with a biologically acceptable particle volume over a long time period, still remains to be seen


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_IV | Pages 400 - 400
1 Apr 2004
de Smet K Durme R Jansegers E Verdonk R
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We present the results of our initial experience with the use of the Birmingham metal-on-metal Hip Resurfacing. The Birmingham Hip Resurfacing(BHR) consists of a high carbon chrome cobalt uncemented hydroxyapatite cupand a cemented femoral component. For patients with severe dysplasia adysplasia cup with screws was used. We utilise this kind of prosthesis for the younger patients (< 65 year). Excellent clinical results are encountered; none of the early problems aswith the old Wagner resurfacing (metal-on-poly) are seen. Our early results are similar to the encouraging results of the series of D.McMinn/R.Treacy. From September 1998 through April 2001, 185 BHR arthroplasties were performed. The mean age was 49.7 year (16–75). More male patients were operated with this method than female patients (64%–36%). The aetiology was osteoarthritis (81%), necrosis (9%), dysplasia (CDH) (6.6%). Results: The last 115 patients were reviewed with a follow up from 1 month to 2.5year. Only two patients were lost for follow-up because of death. There was no pain in 92.3% of the cases. The total Harris Hip Score had a mean of97.91, a median score of 100 (71–100). Merle d’Aubigné total Score was 17.36 (12–18). There was a strenuous activity in 70.2% of the patients. The mean length of stay in hospital was six days (range: 2–26). Complications were: One fractured neck of femur, one ischial nerve palsy and one guide pin was left in the femur. All patients were followed on regular basis and the X-rays were studied for angle of preoperative neck of femur, postoperative angle of the femoral component, angle of cup placement and the parallelism of both components. Conclusion: Performing only alternate bearings in patients under the age of 75, the metal-on-metal Birmingham Hip Resurfacing looks a good alternative in young active patients and the results are promising


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XLI | Pages 71 - 71
1 Sep 2012
Harris J
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My experience with Birmingham Hip Resurfacing began in July 2000 and continues to this day for selected cases including OA, AVN, CDH and also following old fracture deformity and Femoral/Pelvic osteotomy. Early on, the criteria for patient selection expanded with increasing experience and positive acceptance by patients but then moderated as adverse reports including those from our National Joint Replacement Registry suggested a need for caution with Surface Replacement. Over 10 years, (July 2000 — July 2010), a personal series of 243 BHRs were followed (169 male — 74 female) with only one return to theatre in that time (4 days post op. to revise a poorly seated acetabular cup in a dysplastic socket). There were no femoral neck fractures in that 10 year period but 3 femoral cap/stem lucencies were known (2 female-1 male) with insignificant symptoms to require revision. The complete 10 year series of cases were then matched in the Australian National Joint Replacement Registry. No other revisions were identified by the Registry for all 243 cases. Soon after completing this encouraging outcome study however 3 revision procedures have been necessary (2 for sudden late head/neck failure including one of the three with known cap/stem lucencies and one for suspected pseudotumour/ALVAL). One healing stress fracture of the femoral neck and another further cap/stem loosening have also presented recently but with little in the way of symptoms at this stage. Surprisingly, there is little indication which case is likely to present with problems even in the presence of many cases done earlier where one would be cautious now to use a BHR but which have ongoing good outcomes. (e.g., AVN or the elderly osteoporotic patient). My journey therefore with Birmingham Hip Resurfacing over that first 10 years has been very positive and I believe it retains an important place for the younger patient with good bone quality. However it has become only recently apparent in my series of 243 cases that late onset unpredictable problems can arise which is likely to further narrow my selection criteria for this procedure. The likely outcome will be that it will have a more limited place in my joint replacement practice despite the very positive early experience


The Journal of Bone & Joint Surgery British Volume
Vol. 87-B, Issue 2 | Pages 163 - 166
1 Feb 2005
Loughead JM Chesney D Holland JP McCaskie AW

Hip resurfacing is being performed more frequently in the United Kingdom. The possible benefits include more accurate restoration of leg length, femoral offset and femoral anteversion than occurs after total hip arthroplasty (THA). We compared anteroposterior radiographs from 26 patients who had undergone hybrid THA (uncemented cup/cemented stem), with 28 who had undergone Birmingham Hip Resurfacing arthroplasty (BHR). We measured the femoral offset, femoral length, acetabular offset and acetabular height with reference to the normal contralateral hip. The data were analysed by paired t-tests. There was a significant reduction in femoral offset (p = 0.0004) and increase in length (p = 0.001) in the BHR group. In the THA group, there was a significant reduction in acetabular offset (p = 0.0003), but femoral offset and overall hip length were restored accurately. We conclude that hip resurfacing does not restore hip mechanics as accurately as THA


The Journal of Bone & Joint Surgery British Volume
Vol. 93-B, Issue 2 | Pages 158 - 163
1 Feb 2011
Baker RP Pollard TCB Eastaugh-Waring SJ Bannister GC

We compared the medium-term clinical and radiological results of hybrid total hip replacement (THR) with metal-on-metal Birmingham hip resurfacing (BHR) in two groups of 54 young patients matched for age, gender, body mass index and pre-operative levels of activity. The clinical outcome was assessed by the University of California, Los Angeles (UCLA) activity score, the Oxford Hip Score (OHS) and the EuroQol scores. Radiologically, all hips were assessed for migration and osteolysis, the hybrid THRs for polyethylene wear and the BHRs for a pedestal sign. The mean follow-up of the patients with a hybrid THR was ten years and for those with a BHR, nine years. Four patients with a hybrid THR and one with a BHR had died. In each group five were lost to follow-up. The revision rate of the hybrid THRs was 16.7% (9 of 54) and of the BHRs 9.3% (5 of 54) (p = 0.195). Radiographs of a further eight hybrid THRs demonstrated wear and osteolysis, and they await revision (p = 0.008). Of the unrevised BHRs 90% had radiological changes, of which approximately 50% had progressed over the previous four years. All hybrid THRs demonstrated linear polyethylene wear with a mean of 1.24 mm (0.06 to 3.03). The BHRs recorded superior OHS (p = 0.013), UCLA (p = 0.008), and EuroQol visual analogue scores (p = 0.009). After nine years, patients with BHRs remained more active and had a lower rate of revision than those with hybrid THRs. Both groups demonstrated progressive radiological changes at medium-term follow-up


The Journal of Bone & Joint Surgery British Volume
Vol. 90-B, Issue 6 | Pages 715 - 723
1 Jun 2008
McMinn DJW Daniel J Ziaee H Pradhan C

The dysplasia cup, which was devised as an adjunct to the Birmingham Hip Resurfacing system, has a hydroxyapatite-coated porous surface and two supplementary neutralisation screws to provide stable primary fixation, permit early weight-bearing, and allow incorporation of morcellised autograft without the need for structural bone grafting. A total of 110 consecutive dysplasia resurfacing arthroplasties in 103 patients (55 men and 48 women) performed between 1997 and 2000 was reviewed with a minimum follow-up of six years. The mean age at operation was 47.2 years (21 to 62) and 104 hips (94%) were Crowe grade II or III. During the mean follow-up of 7.8 years (6 to 9.6), three hips (2.7%) were converted to a total hip replacement at a mean of 3.9 years (2 months to 8.1 years), giving a cumulative survival of 95.2% at nine years (95% confidence interval 89 to 100). The revisions were due to a fracture of the femoral neck, a collapse of the femoral head and a deep infection. There was no aseptic loosening or osteolysis of the acetabular component associated with either of the revisions performed for failure of the femoral component. No patient is awaiting a revision. The median Oxford hip score in 98 patients with surviving hips at the final review was 13 and the 10th and the 90th percentiles were 12 and 23, respectively


The Journal of Bone & Joint Surgery British Volume
Vol. 89-B, Issue 4 | Pages 557 - 560
1 Apr 2007
Davis ET Gallie P Macgroarty K Waddell JP Schemitsch E

A cadaver study using six pairs of lower limbs was conducted to investigate the accuracy of computer navigation and standard instrumentation for the placement of the Birmingham Hip Resurfacing femoral component. The aim was to place all the femoral components with a stem-shaft angle of 135°. The mean stem-shaft angle obtained in the standard instrumentation group was 127.7° (120° to 132°), compared with 133.3° (131° to 139°) in the computer navigation group (p = 0.03). The scatter obtained with computer-assisted navigation was approximately half that found using the conventional jig. Computer navigation was more accurate and more consistent in its placement of the femoral component than standard instrumentation. We suggest that image-free computer-assisted navigation may have an application in aligning the femoral component during hip resurfacing


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 356 - 356
1 Sep 2005
Shimmin A Back D
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Introduction: Hip resurfacing has undergone a resurgence of interest in the past five years. With it, the awareness of femoral neck fractures associated with this prosthesis has grown. We report the first national review of femoral neck fractures over a four-year period. Method: All surgeons using the Birmingham hip resurfacing in Australia were contacted and asked to supply details of any femoral neck fractures they had experienced. Routine co-morbidities and demographics were collated. Results: Fifty fractures have occurred in the time period. The fracture rate was twice as high in women than men and this was statistically significant (p< 0.001). Mean time to fracture was 15 weeks and was slightly longer in women than men. Technical difficulties included notching of the femoral neck, varus placement of the femoral prosthesis, poor exposure due to obesity and poor impaction of the femoral component. Conclusions: The national fracture rate associated with the Birmingham hip resurfacing is 1.46%


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_18 | Pages 6 - 6
1 Nov 2016
Lim J Foster N Ridley D Johnston L Clift B
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The use of Birmingham hip resurfacing (BHR) remains controversial due to the increased revision rate in female patients. We compared the outcomes of BHR in female patients to an age matched total hip arthroplasty(THA) cohort. We reviewed the pain, function and total Harris Hip Scores(HHS), and Kaplan-Meir survivorship for BHR and THA cohorts from a prospective regional arthroplasty database. There were 234 patients in each cohort, with mean age of 51 years. The BHR cohort had significantly better function and total HHS at all points of the 5-year study, but not for the post-operative pain score. The 5-year revision rate for the BHR cohort was significantly higher than the THA cohort (6.8% vs 3.4%, p=0.001). The main reason for revision in the BHR cohort was aseptic loosening (n=8), followed by metallosis (n=3). The 5-year Kaplan-Meier survivorship was 92.6% (95% CI±1.7%) and 96.4% (95% CI±1.3%) for the BHR and THA cohort (p=0.001). BHR can give significantly better functional outcomes than THA. The vast majority of female patients were happy with BHR and did not need further surgery at the 5-year stage. This is somewhat at odds with the recent reputation of the procedure. The 10-year result of the same cohort is warranted to provide further data. Our study is not a recommendation to still offer BHR to female patients, but rather to inject a note of realism into the debate. There are implications for future implant development in that these results do validate resurfacing as a functionally valuable option for active patients


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_12 | Pages 24 - 24
1 Jun 2017
Jonas S Bick S Whitehouse M Bannister G Baker R
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We compared the long-term clinical and radiological results of hybrid total hip replacement (THR) with metal-on-metal Birmingham hip resurfacing (BHR) in two groups of 54 young patients matched for age, gender, body mass index and pre-operative levels of activity. The clinical outcome was assessed by the University of California, Los Angeles (UCLA) activity score, the Oxford Hip Score (OHS) and the EuroQol scores. Radiologically, all hips were assessed for migration and osteolysis, the hybrid THRs for polyethylene wear and the BHRs for a pedestal sign. The mean follow-up of the patients with a hybrid THR was 16 years and for those with a BHR, 15 years. 12 patients with a hybrid THR and 6 with a BHR had died. 2 patients with a BHR refused follow up but remain unrevised and 5 were lost to follow-up, as was 1 with a hybrid THR. The revision rate of the hybrid THRs was 28% (15 of 54) and of the BHRs 11% (6 of 54) (p = 0.029). Radiographs of a further 13 hybrid THRs demonstrated wear and osteolysis but are functioning well and are under observation. Of the unrevised BHRs 96% had radiological changes, of which approximately 17% had progressed over the previous 6 years. All hybrid THRs demonstrated linear polyethylene wear with a mean of 1.84mm (0.06 to 2.6). The BHRs recorded superior OHS (p = 0.03), UCLA (p = 0.0096), and EuroQol visual analogue scores (p = 0.03). After 15 years, patients with BHRs remained more active and had a lower rate of revision and death than those with hybrid THRs. Both groups demonstrated progressive radiological changes at long-term follow-up


The Journal of Bone & Joint Surgery British Volume
Vol. 89-B, Issue 2 | Pages 169 - 173
1 Feb 2007
Daniel J Ziaee H Pradhan C Pynsent PB McMinn DJW

This is a longitudinal study of the daily urinary output and the concentrations in whole blood of cobalt and chromium in patients with metal-on-metal resurfacings over a period of four years. Twelve-hour urine collections and whole blood specimens were collected before and periodically after a Birmingham hip resurfacing in 26 patients. All ion analyses were carried out using a high-resolution inductively-coupled plasma mass spectrometer. Clinical and radiological assessment, hip function scoring and activity level assessment revealed excellent hip function. There was a significant early increase in urinary metal output, reaching a peak at six months for cobalt and one year for chromium post-operatively. There was thereafter a steady decrease in the median urinary output of cobalt over the following three years, although the differences are not statistically significant. The mean whole blood levels of cobalt and chromium also showed a significant increase between the pre-operative and one-year post-operative periods. The blood levels then decreased to a lower level at four years, compared with the one-year levels. This late reduction was statistically significant for chromium but not for cobalt. The effects of systemic metal ion exposure in patients with metal-on-metal resurfacing arthroplasties continue to be a matter of concern. The levels in this study provide a baseline against which the in vivo wear performance of newer bearings can be compared