MRI has been suggested as an objective method of assessing anterior crucate ligament (ACL) graft “ligamentization” after reconstruction. It has been proposed that the MRI appearances could be used as an indicator of graft maturity and used as part of a return-to-sport assessment. The aim of this study was to evaluate the correlation between MRI graft signal and postoperative functional scores, anterior knee laxity, and patient age at operation. A consecutive cohort of 149 patients who had undergone semitendinosus autograft ACL reconstruction, using femoral and tibial adjustable loop fixations, were evaluated retrospectively postoperatively at two years. All underwent MRI analysis of the ACL graft, performed using signal-to-noise quotient (SNQ) and the Howell score. Functional outcome scores (Lysholm, Tegner, International Knee Documentation Committee (IKDC) subjective, and IKDC objective) were obtained and all patients underwent instrumented side-to-side anterior laxity differential laxity testing.Aims
Methods
Aims. The effects of remnant preservation on the
Aims. The aim of this study was to report the pooled prevalence of post-traumatic osteoarthritis (PTOA) and examine whether the risk of developing PTOA after
Aims. The aim of this study was to estimate the incremental use of resources, costs, and quality of life outcomes associated with surgical reconstruction compared to rehabilitation for long-standing
Aims. The
Aims. Post-traumatic osteoarthritis (PTOA) is a subset of osteoarthritis (OA). The gut microbiome is shown to be involved in OA. However, the effect of exercise on gut microbiome in PTOA remains elusive. Methods. A total of 18 eight-week Sprague-Dawley rats were assigned into three groups: Sham/sedentary (Sham/Sed), PTOA/sedentary (PTOA/Sed), and PTOA/treadmill-walking (PTOA/TW). PTOA model was induced by transection of the
The
Aims. The aim of this study was to screen the entire genome for genetic markers associated with risk for
The
Aims. The objectives of this study were to assess the effect of
External validation of machine learning predictive models is achieved through evaluation of model performance on different groups of patients than were used for algorithm development. This important step is uncommonly performed, inhibiting clinical translation of newly developed models. Recently, machine learning was used to develop a tool that can quantify revision risk for a patient undergoing primary
Aims. This study aims to determine the proportion of patients with end-stage knee osteoarthritis (OA) possibly suitable for partial (PKA) or combined partial knee arthroplasty (CPKA) according to patterns of full-thickness cartilage loss and
Aims. The aim of this prospective study was to assess the long-term clinical, radiological, functional, and quality of life (QoL)-related outcome of patients treated with the synthetic Ligament Advanced Reinforcement System (LARS) device for
Successful
Aim. Quadrupled hamstring
Objectives. In this study, we compared the pain behaviour and osteoarthritis (OA) progression between
Increasing expectations from arthroscopic
We sought to determine whether smoking affected the outcome of reconstruction of the
We reviewed 183 patients who had undergone reconstruction of the
There is a trend towards the use of double-bundle techniques for the reconstruction of the
Aims.
Due to unsatisfactory results and reported drawbacks of
Abnormal knee kinematics following reconstruction
of the
We report the effects of local administration of osteogenic protein-1 on the biomechanical properties of the overstretched
Reconstruction of the
Aims. Proliferation, migration, and differentiation of
While injury to the posterolateral corner is accepted as a relatively common occurrence associated with rupture of the
We present the results of 17 children of Tanner stage 1 or 2 who underwent reconstruction of the
Aims. Different methods of
The records of patients aged 50 years or over who underwent primary reconstruction of the
The aim of the this study was to determine the effect of the knee flexion angle (KFA) during tibial
Delayed rather than early reconstruction of the
Recent findings have identified the importance of previously undiagnosed or neglected meniscus lesions in association with
Ten patients are reported who had sustained a partial rupture of the
We report the clinical outcome and findings at
second-look arthroscopy of 216 patients (mean age 25 years (11 to 58))
who underwent
We carried out a prospective study of 71 patients who had undergone reconstruction of the
The concept of decellularised xenografts as a basis for
Machine-learning (ML) prediction models in orthopaedic trauma hold great promise in assisting clinicians in various tasks, such as personalized risk stratification. However, an overview of current applications and critical appraisal to peer-reviewed guidelines is lacking. The objectives of this study are to 1) provide an overview of current ML prediction models in orthopaedic trauma; 2) evaluate the completeness of reporting following the Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD) statement; and 3) assess the risk of bias following the Prediction model Risk Of Bias Assessment Tool (PROBAST) tool. A systematic search screening 3,252 studies identified 45 ML-based prediction models in orthopaedic trauma up to January 2023. The TRIPOD statement assessed transparent reporting and the PROBAST tool the risk of bias.Aims
Methods
This study evaluated the results of a physeal-sparing technique of intra-articular
In the UK, the agricultural, military, and construction sectors have stringent rules about the use of hearing protection due to the risk of noise-induced hearing loss. Orthopaedic staff may also be at risk due to the use of power tools. The UK Health and Safety Executive (HSE) have clear standards as to what are deemed acceptable occupational levels of noise on A-weighted and C-weighted scales. The aims of this review were to assess the current evidence on the testing of exposure to noise in orthopaedic operating theatres to see if it exceeds these regulations. A search of PubMed and EMBASE databases was conducted using PRISMA guidelines. The review was registered prospectively in PROSPERO. Studies which assessed the exposure to noise for orthopaedic staff in operating theatres were included. Data about the exposure to noise were extracted from these studies and compared with the A-weighted and C-weighted acceptable levels described in the HSE regulations.Aims
Methods
More than 250,000 people are suffering from
The medial meniscus is crescent shaped and it is wider posteriorly than anteriorly. It covers up to 60 % of the articular surface of medial tibial condyle and helps with the loading distribution in the medial compartment. Meniscal lesions occur in association with ACL tears in 60 % of the time. The posterior aspect of the menisco-capsular junction is known as the meniscal rampzone. If not addressed during surgery, it could lead to unfavourable results. Incidence of ramp lesion following ACL injuries.Abstract
Introduction
Objective
We reviewed a single-surgeon series of 300 athletic patients who had undergone reconstruction of the
To report the long term outcome of patients with a partial tear of the
We used single-photon emission computed tomography (SPECT) to determine the long-term risk of degenerative change after reconstruction of the
Introduction: Clinical presentation of mucoid degeneration of the
We have investigated the changes in anterior laxity of the knee in response to direct electrical stimulation of eight normal and 45 reconstructed
Introduction.
Introduction. A common problem for patients receiving total knee arthroplasty (TKA) is postoperative functional impairment of the joint. This is minimized in bicruciate-retaining (ACL preserving) knee replacements, due to the important role of the
Purpose: Cyclope syndrome is described in the literature as a postoperative complication of arthroscopic
We have investigated whether cells derived from haemarthrosis caused by injury to the
The clinical and radiological features of 12 knees (10 patients) with congenital absence of the
A total of 108 patients with unilateral instability of the knee, associated with rupture of the
Objectives. This study aimed to investigate time-dependent gene expression
of injured human
The revascularisation and remodelling of allografts used to replace the
Joint registries classify all further arthroplasty procedures to a knee with an existing partial arthroplasty as revision surgery, regardless of the actual procedure performed. Relatively minor procedures, including bearing exchanges, are classified in the same way as major operations requiring augments and stems. A new classification system is proposed to acknowledge and describe the detail of these procedures, which has implications for risk, recovery, and health economics. Classification categories were proposed by a surgical consensus group, then ranked by patients, according to perceived invasiveness and implications for recovery. In round one, 26 revision cases were classified by the consensus group. Results were tested for inter-rater reliability. In round two, four additional cases were added for clarity. Round three repeated the survey one month later, subject to inter- and intrarater reliability testing. In round four, five additional expert partial knee arthroplasty surgeons were asked to classify the 30 cases according to the proposed revision partial knee classification (RPKC) system.Aims
Methods
We identified a series of 128 patients who had unilateral open reconstruction of the
Purpose: Radiologists describe cysts of the
There is little evidence examining the relationship between anatomical landmarks, radiological placement of the tunnels and long-term clinical outcomes following
Introduction and Aims: There are more than 200,000
It has been suggested that an increased posterior
tibial slope (PTS) and a narrow notch width index (NWI) increase
the risk of
In a prospective study, 41 consecutive patients with a partial tear of the
Introduction. Rupture of the
Introduction. Cruciate retaining knee replacements are only implanted into patients with “healthy” ligaments. However, partial
Purpose of the study:
There is renewed interest in bi-unicondylar arthroplasty (Bi-UKA) for patients with medial and lateral tibiofemoral osteoarthritis, but a spared patellofemoral compartment and functional cruciate ligaments. The bone island between the two tibial components may be at risk of tibial eminence avulsion fracture, compromising function. This finite element analysis compared intraoperative tibial strains for Bi-UKA to isolated medial unicompartmental arthroplasty (UKA-M) to assess the risk of avulsion. A validated model of a large, high bone-quality tibia was prepared for both UKA-M and Bi-UKA. Load totalling 450N was distributed between the two ACL bundles, implant components and collateral ligaments based on experimental and intraoperative measurements with the knee extended and appropriately sized bearings used. 95th percentile maximum principal elastic strain was predicted in the proximal tibia. The effect of overcuts/positioning for the medial implant were studied; the magnitude of these variations was double the standard deviation associated with conventional technique.Abstract
Objectives
Methods
We reviewed 195 knees in 167 patients at least 20 years after a rim-preserving meniscectomy. They were considered in two groups: 102 knees had had an intact
Introduction: Rupture of the
Purpose of the study: Cysts are rarely identified in the
Introduction. This study explores whether subjects with bicruciate retaining TKRs (BiCR) have more normal knee biomechanics during level walking and stair ascent than subjects with posterior cruciate retaining TKRs (PCR). Due to
The efficacy of thermal modulation of collagen utilizing an electrothermal device to treat low to moderate demand patients with mid-substance
Introduction: Medial unicompartmental knee replacement (UKR) is a successful procedure in the management of early osteoarthrosis. This procedure is not usually indicated in patients who have insufficiency of the
We have measured anterior and posterior displacement in 563 normal knees and 487 knees with chronic deficiency of the
We studied bone-tendon healing using immunohistochemical methods in a rabbit model. Reconstruction of the
The management of symptomatic single bundle
Aims: To determine the difference between macroscopic and microscopic appearances of the
We examined whether somatosensory evoked potentials (SEPs) were detectable after direct electrical stimulation of injured, reconstructed and normal
Purpose: The purpose of our tissue engineering work was to produce a substitute for the
Purpose of the study: This work examined the clinical, radiological, and videoarthroscopic features of partial tears of the
In an animal model we determined the strength of
Cell sheets are manufactured from a high-density cell layer stabilized by its own freshly produced extracellular matrix (ECM). They could serve as versatile scaffolds for tissue repair. Unfortunately, their production often remains time-consuming requiring weeks of culturing. Ligament cell sheets are so far barely available. Regarding musculoskeletal tissues exposed to high repetitive biomechanical forces, the stability of cell sheets is insufficient. It could help to combine them with a biomechanical competent scaffold e.g. produced by an embroidering technique. Hence, we wanted to (1) develop a very rapid strategy to produce ACL ligamentocyte sheets within 24 h by using a thermoresponsive polymer surface, (2) use the sheets for scaffold seeding and (3) reflect the fibrocartilaginous transition zone of an ACL enthesis by combining sheets of ligamentocytes with chondrocytes or chondrogenic precursor cells as a strategy for directed seeding of two cell types on topologically different scaffold areas. Different cell numbers of lapine ACL ligamentocytes (L-ACLs), lapine articular chondrocytes (L-ACs) and human mesenchymal stromal cells (H-MSCs) were used for sheet formation. Experiments were performed with novel, self-assembled poly(glycidyl ether) (PGE) brushes based on random glycidyl methyl ether and ethyl glycidyl ether copolymers on polystyrene 12-well cell culture plates, which allow rapid sheet formation within 24 h. Uncoated plates served as controls. Temperature-triggered detachment was performed by 10 min incubation with PBS at ambient temperature before treatment with fresh warm PBS for 5 min at 37 degrees Celsius. Harvested cell sheets were transferred on polyglycolic acid (PGA) or embroidered poly-lactic acid / poly-co-caprolactone (PLA/P[LA-CL]) scaffolds, functionalized with collagen foam and fluorine gas treatment (prepared at the IPF in Dresden and the FILK in Freiberg). Cell distribution, growth, vitality and synthesis of ECM components were monitored up to 7 days. Cell numbers required for sheet preparation (3.9 cm2) depended strongly on the cell type (L-ACLs: 0.395 mio/cm2, L-AC: 0.342 mio/cm2, H-MSCs: 0.131 mio/cm2) and was highest for L-ACLs. The majority of cells survived sheet assembly, detachment, transfer onto the scaffolds and culturing. Cells migrated from the sheets into the scaffolds and spread through the scaffolds. L-ACLs and L-ACs produced ECM and maintained their phenotypes (type II collagen and sulfated glycosaminoglycans in L-AC sheets, decorin and tenascin C in L-ACL sheets). The presence and distribution of two cell types in scaffold cocultures (L-ACLs and H-MSCs) was proven by anti-human vimentin labeling. Hence, the PGE brush surface allows rapid formation (24 h) of cell sheets.
Sixty-five knees were subjected to a kinematic analysis using the instant-centre technique in order to determine the effect of deficiency of the
Purpose: Several studies have reported results of
The purpose to prospectively compare two types of tibial fixation in a series of 160
The use of platelet-rich plasma (PRP) as an adjuvant
to tissue repair is gaining favour in orthopaedic surgery. Tunnel widening
after
Our objectives were to establish the envelope of passive movement and to demonstrate the kinematic behaviour of the knee during standard clinical tests before and after reconstruction of the
A total of 30 patients who underwent endoscopic reconstruction of the
A group of 40 patients with unstable knees due to a combination of a meniscal tear with a rupture of the
We randomised 31 patients with acute tears of the
The operative treatment of lesions of the
Introduction/aims.
We have undertaken a randomized clinical trial comparing two methods of reconstruction of the
A total of 90 patients with an isolated rupture of the
In a two-centre study, 164 patients with unilateral instability of the
Evidence suggests that
Dynamic muscle-tendon substitution for acute anterior cruciate deficiency in the dog was studied using the semimembranosus muscle-tendon. Nineteen mongrel dogs each had a semimembranosus transfer in one knee; as a control, the
The physiological role of mechanoreceptors in the
Purpose:
Purpose: The