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Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXII | Pages 4 - 4
1 Jul 2012
Boyd M Anderson T Middleton S Brinsden M
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Skills simulation is increasingly used as a training tool in postgraduate surgical training. Trainee's perception of the value of this experience has not previously been investigated. The aim of this investigation was to investigate the value of surgical simulation training delivered by an arthroscopy skills course.

We constructed a subject-specific, self-assessment questionnaire based around the ISCP Peer Assessment Tool. The questionnaire was administered to candidates before and after attending the Plymouth Arthroscopy Skills Course. Participant demographic data was recorded. Questionnaire data was interrogated to give an overview of the course, as well as the benefit of site-specific skills stations. Statistical analysis showed the data to be normally distributed. The paired T-test was used to compare mean values.

Twelve surgical trainees attended the course – CT2 trainees (n=4); ST3 trainees (n=7); ST4 trainee (n=1). 11 candidates completed both administered questionnaires giving a 92% response rate. The global mean score at the beginning of the course was 2.39. The global mean score at the end of the course was 3.90. The mean improvement was 1.51 (p<0.01; 95% CI= 0.96-2.07). Skill station specific scores all showed improvement with the greatest effect in wrist arthroscopy. CT trainees had a lower mean score compared to ST trainees. Both groups completed the course with similar mean scores.

This study shows that arthroscopy simulation improves trainee-reported ratings of surgical skill. It also shows that less experienced candidates derived the greatest benefit from the training. Further research is required to compare self-assessed performance against objective benchmarks using validated assessment tools.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXII | Pages 20 - 20
1 Jul 2012
Middleton S Guyver P Boyd M Anderson T Brinsden M
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Military patients have high functional requirements of the upper limb and may have lower pre-operative PROM scores than civilian patients i.e. their function is high when benchmarked, but still insufficient to perform their military role thereby mandating surgery. Our aim was to compare the pre-operative Oxford Shoulder Instability Scores in military and civilian patients undergoing shoulder stabilisation surgery.

We undertook a prospective, blinded cohort-controlled study (OCEBM Level 3b). The null hypothesis was that there was no difference in the Oxford Shoulder Instability Scores between military and civilian groups. A power calculation showed that 40 patients were required in each group to give 95% power with 5% significance. A clinical database (iParrot, ByResults Ltd., Oxford, UK) was interrogated for consecutive patients undergoing shoulder stabilisation surgery at a single centre. The senior author - blinded to the outcome score - matched patients according to age, gender and diagnosis. Statistical analysis showed the data to be normally distributed so a paired samples t-test was used to compare the two groups. 110 patients were required to provide a matched cohort of 80 patients.

There were 70 males and 10 females. Age at the time of surgery was 16-19yrs (n=6); 20-24yrs (n=28); 25-29 (n=16); 30-34(n=12); 35-49(n=12); 40-44(n=6). 72 patients (90%) had polar group one and 8 patients (10%) had polar group two instability. The mean Oxford Shoulder Instability Score in the civilian group was 17 and the in military group was 18. There was no statistical difference between the two groups (p=0.395).

This study supports the use the Oxford Shoulder Instability Score to assess military patients with shoulder instability.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXVIII | Pages 16 - 16
1 Jun 2012
Russell D Pillai A Anderson K Kumar C
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Regional anaesthetic for foot surgery has been discussed as a method of post operative analgesia. Ankle block as the sole anaesthetic for foot surgery has not been extensively reviewed in the literature. We aimed to describe our experience of forefoot surgery under ankle block.

Sixty-six consecutive forefoot procedures (59 patients) were carried out under ankle block. Patients were contacted post operatively and completed a standardised questionnaire including an incremental pain assessment ranging from 0-10 (0 no pain, 10 severe pain).

Forty nine female and 10 male patients (age range 20-85y) were included. Procedures included 33 first metatarsal osteotomies, 15 cheilectomies, 3 first MTP joint replacements, 5 fusions, 4 excision of neuroma and 6 other procedures. 22 patients (33% of cases) reported discomfort during the block procedure (average pain score 1.5). 6 patients reported pain during their operation(s), average score 0.26. Average pain scores at 6, 12, 24 and 48 hours following surgery were 2.0, 3.2, 2.7 and 2.1 respectively. All patients were discharged home and walking on the same day. There were no readmissions. Each patient confirmed they would have surgery under regional block rather than general anaesthesia and would recommend this technique to family and friends.

There are many advantages in being able to perform these relatively small procedures under regional anaesthesia. The anaesthesia obtained permits the majority of forefoot procedures and provides lasting post-operative analgesia. Combined with intra-operative sedation, use of ankle tourniquet and same day discharge; it has very high patient acceptance and satisfaction.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXII | Pages 34 - 34
1 May 2012
Russell D Pillai A Anderson K Kumar C
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Regional anaesthetic for foot surgery has been discussed as a method of post operative analgesia. Ankle block as the sole anaesthetic for foot surgery has not been extensively reviewed in the literature.

Aim

To describe our experience of forefoot surgery under ankle block.

Methods

71 consecutive forefoot procedures (65 patients) were carried out under ankle block. A mixture of 10ml 2% Lidocaine with 10ml 0.5 % Bupivacine was administered to the superficial peroneal, deep peroneal, sural and saphenous nerves. Ankle tourniquet was employed in all procedures. Patients were contacted post operatively and completed a standardised questionnaire including an incremented pain assessment ranging from 0-10 (0 no pain, 10 severe pain).


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XI | Pages 26 - 26
1 Apr 2012
Russell D Pillai A Kumar C Anderson K
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Regional anaesthetic for foot surgery has been discussed as a method of post operative analgesia. Ankle block as the sole anaesthetic for foot surgery has not been extensively reviewed in the literature.

We aimed to describe our experience of forefoot surgery under ankle block alone. 21 consecutive forefoot procedures (18 patients) were carried out under ankle block. The blocks were performed by the senior authors. A mixture of 10ml 2% Lidocaine with 10ml 0.5 % Bupivacaine was administered to the superficial peroneal, deep peroneal, sural and saphenous nerves. Ankle tourniquet was employed in all procedures. The patients were contacted post operatively and completed a standardised questionnaire including an incremented pain assessment ranging from 0-10 (0 no pain, 10 severe pain). 17 female and 1 male patients were contacted (age range 33-67y). Procedures included 13 first metatarsal osteotomies, 3 cheilectomies, 2 first MTP joint replacements, and 5 fusions. 14 patients requested a short acting sedative (midazolam). 5 patients (27 %) reported some discomfort during the block procedure (average pain score 1.2). No patients reported any pain during their operation(s). 4 patients (22%) required supplementation of the block. Average pain score at 6, 12, 24 and 48 hours following surgery were 0.66, 2.9, 2.4 and 1.3 respectively. All patients were discharged home and walking on the same day. None complained of nausea or required parenteral analgesia; there were no readmissions. Each patient confirmed they would have surgery under local block rather than general anaesthesia and would recommend this technique to family and friends.

Forefoot surgery under ankle block alone is safe and effective. Anaesthesia obtained permits the majority of forefoot procedures and provides lasting post-operative analgesia. Combined with intraoperative sedation, use of ankle tourniquet and same day discharge, it has very high patient acceptance and satisfaction.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_III | Pages 149 - 149
1 Feb 2012
Anderson A Smyth E Hamer A
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To assess whether prosthetic femoral stem centralisers have a detrimental effect on the macroporosity of the cement mantle, and if so, whether this is independent of their design and the rate of implantation, 30 identically cast moulded prosthetic femora were divided into 3 groups. Group 1: no centraliser (control), Group 2: centraliser A and Group 3: centraliser B. Using third generation cementation techniques and pressure monitoring, Charnley C-stems +/− the appropriate centraliser were implanted to a constant depth. Half in each group were implanted as rapidly as possible and the other half over 90 seconds. The stems were removed and the cement mantle then underwent a preliminary arthroscopic examination prior to being sectioned transversely at 3 constant levels. Each level was then photographed and digitally enlarged to a known scale to allow examination and determination of any cement voids (macropores) surface area.

There were no significant pressure fluctuations between the groups. Preliminary arthroscopic examination revealed that cement voids appeared more common when a centraliser was used. This difference was confirmed (p=0.002) following sectioning of the specimens, with cement voids found in 85% of femora when a centraliser was used and only 20% in the control group. Centraliser B performed worst with cement voids of a larger volume and more frequent occurrence (p=0.002). The macroporosity of the cement mantle was independent of the rate of implantation (p=0.39).

The use of femoral stem centralisers is helpful in preventing malposition of the implant but results in increased macroporosity of the cement mantle. This may have implications regarding the longevity of an implant in terms of early loosening and therefore their design and use must always be carefully considered.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 419 - 419
1 Nov 2011
Heuer D Williams M Moss R Butcher K Anderson M Milner R Alley C Gilmour L Scott M
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This study evaluated the biologic fixation of two different titanium porous coatings: a clinically successful sintered spherical bead coating [1] and a new sintered asymmetric particle coating (STIKTITE™, Smith & Nephew). The spherical bead coating has a porosity of about 50% and an average pore size of about 220 μm, whereas the STIKTITE coating has greater porosity (about 62%) and slightly smaller average pore size (about 200 μm). Biologic fixation was assessed using a load-bearing ovine model in which coated semi-circular disc implants were inserted into a defect created in the cancellous bone parallel to and approximately 3 mm below the medial tibial plateau [2] similar to the method reported by Ignatius [3]. The implants were slightly thicker than the defect created, producing a 0.2-mm overall pressfit. Initial implant stability was assessed using mechanical push-out (n = 3) immediately after implantation into cadaveric ovine bone. Quantitative mechanical push-out testing and qualitative histology (n = 9 and n = 2, respectively, per group per time point) was performed after six and 26 weeks in vivo.

The time-zero average peak push-out load (±S.D.) of the STIKTITE group (95±3 N) was found to be significantly greater (p < 0.02) than that of the spherical bead group (36±5 N). By six weeks in vivo, the average peak push-out load for the STIKTITE group was up to 1001±362 N, and that for the spherical bead group was up to 985±425 N, both representing a significant increase compared to their time-zero results (p < 0.0005). From six to twenty-six weeks in vivo, there was again a significant increase in the peak push-out load irrespective of group (p < 0.0005), with the average peak push-out loads up to 1620±406 N and 1444±446 N for the STIK-TITE and spherical bead groups, respectively. Histology revealed bone ingrowth in both groups that confirmed the findings of the mechanical push-out testing. While the STIKTITE group showed a trend toward greater biologic fixation, overall there was insufficient evidence to support differences between the two groups (p = 0.47) irrespective of the amount of time in vivo.

The results of this study confirm the ability of the STIK-TITE coating to achieve superior initial stability. This improved initial stability reduces the reliance on adjunct fixation (such as screws) or large amounts of press-fit to prevent micromotion and create an environment suitable for long-term bone ingrowth. The results also suggest that the STIKTITE coating had a tendency to initiate and maintain bone ingrowth under load-bearing conditions to a level greater than that of a clinically successful sintered bead coating. Because loading of the implant can cause micromotion at the bone/implant interface, models like the one used in this study likely provide a more challenging and realistic representation of anticipated clinical conditions than models with minimal implant loading.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 381 - 381
1 Jul 2011
Munro J Shim V Anderson I Pitto R
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Aseptic loosening is the leading cause for revision in total hip arthroplasty. Retro-acetabular lysis is often a silent process until severe bone loss causes catastrophic failure. This presents a technically difficult problem for the surgeon and a poorer result for the patient compared to primary arthroplasty. While the major cause of osteolysis is reaction to polyethylene particles, there is little data on the initiation and progression of such lesions. Further, alterations in the mechanical environment caused by such pathology is unclear. We present our use of 3D, finite element (FE) models of retro-acetabular pathology to investigate the biomechanical effects of osteolysis in total hip arthroplasty. Axial CT scan slices from a patient with cystic osteolysis were selected. Areas of cortical bone, cancellous bone, the cup and the cyst are accurately identified. The axial images are matched to a predetermined grid and used to build a complex finte element model. In this way complex anatomy can be built into the FE model and used to map cystic lesions. Force is then applied to the acetabulum.

Initial analysis shows similar stress transmission in cystic disease compared to the post operative pelvis. Pelvic bone still behaves as a sandwich construct with transmission from the acetabulum to the SI joints, pubic symphysis and medial wall. In the setting of pelvic medial wall deficiency, stress transmission is altered with areas of low stress around the defect.

The FE models containing pathology can be compared to models with generic bone density values immediately after total hip arthroplasty. The presence of a cyst in cancellous bone with intact cortical bone, demonstrates strain patterns similar to the post operative pelvis. Once cortical bone loss occurs strain patterns begin to change. This may mark a critical point in osteolytic progression. We present a developing new tool to be used in the assessment of a patient population with retroacetabular cystic disease.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 381 - 381
1 Jul 2011
Segar A Malak S Anderson I Pitto R
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Correct positioning of the femoral component in resurfacing hip arthroplasty (RHA) is an important factor in successful long-term patient outcomes. Computer-assisted navigation (CAS) shows potential to improve implant positioning and possibly prolong survivorship in total hip and knee arthroplasty. The purposes of CAS systems in resurfacing the femoral head are to insert the femoral head and neck guide wire with greater accuracy and to help in sizing the femoral component, thus reducing the risk of notching of the head and neck junction. Several recent studies reported satisfactory precision and accuracy of CAS in RHA. However, there is little evidence that computer navigation is useful in the presence of anatomical deformities of the proximal femur, which is frequently observed in young patients with secondary degenerative joint disease.

The purpose of this in-vitro study was to determine the accuracy of an image-free resurfacing hip arthroplasty navigation system in the presence of two femoral deformities: pistol grip deformity of the head and femoral neck junction and slipped upper femoral epiphysis deformity. An artificial phantom leg with a simulated hip and knee joint was constructed from machined aluminum. Implant-shaft angles for the guide wire of the femoral component reamer were calculated, in frontal and lateral planes, with both a computer navigation system and an electronic caliper combined with micro-CT.

With normal anatomy we found close agreement between the CAS system and our measurement system. However, there was a consistent disagreement in both the frontal and lateral planes for the pistol grip deformity. Close agreement was found only on the frontal plane angle calculation in the presence of the slipped upper femoral epiphysis deformity, but calculation of the femoral head size was inaccurate.

This is the first study designed to assess the accuracy of a femoral navigation system for resurfacing hip arthroplasty in the presence of severe anatomical deformity of the proximal femur. Our data suggests CAS technology should not be used to expand the range of utilisation of resurfacing surgery, but rather to improve the surgical outcome in those with suitable anatomy.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 262 - 262
1 Jul 2011
Woodhouse LJ Petruccelli D Wright J Elliott W Toffolo N Patton S Samanta S Sardo A MacMillan D Johnson G Anderson C Evans W
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Purpose: Reducing wait times for total hip (THA) or knee (TKA) joint arthroplasty is a Canadian health care priority. Models that maximise the capacity of advanced practice clinicians (nurses, physical therapists, sports medicine specialists) have been established to streamline care. Hospitals across the Hamilton Niagara Haldimand Brant Local Health Integration Network in Ontario collaborated to establish a Regional Joint Assessment Centre (RJAC). This study was designed to profile patients deemed suitable for surgical review, and to examine wait times for THA or TKA in RJAC patients compared to those referred directly to an orthopaedic surgeon’s office.

Method: Patients referred to the RJAC between July 2007 and August 2008 with knee or hip OA were included. Self-reported function was evaluated using the Oxford Hip and Knee Score that is scored out of 60 (higher scores reflect greater disability). Time to surgery was measured as the number of days from initial review to surgery. Group one consisted of patients that were referred to the RJAC while group two was comprised of patients who were referred directly to a surgeon’s office. Patient characteristics were examined using univariate analyses. Independent t-tests were used to examine between group differences.

Results: One hundred thirty-six patients (mean±sd: 68±2 years, body mass index 31±6 kg/m2, 83 females) with 150 hip and/or knee joint problems were reviewed in the RJAC. Of those, only 33% (45/136 patients) were deemed suitable for surgical review. Self-reported function (Oxford Scores) in the group requiring surgical review was significantly worse (40±7, p=0.03) than in those patients deemed unsuitable for surgical review (37±9). The RJAC group waited on average 130 days for THA and 129 days for TKA (below the provincial target of 182 days) while those referred directly to the surgeons’ offices waited significantly longer (194 days for THA and 206 days for TKA, p< 0.001).

Conclusion: Patients with hip and knee OA who require surgical review have worse self-reported function than those triaged to conservative care. Wait times for THA or TKA were significantly shorter for patients referred to the RJAC under the new model of care than for those referred directly to an orthopaedic surgeon’s office.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_III | Pages 460 - 460
1 Jul 2010
Oberlin O Rey A La T Bisogno G Koscielniak E Stevens M Meyer W Carli M Anderson J
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Objective: To determine patient characteristics and outcomes for extremity rhabdomyosarcoma (RMS) utilizing an international cohort of prospectively treated patients.

Methods: Data were collected from 566 patients (1984 through 2003) treated on cooperative protocols : US IRS III, IV Pilot, IV studies – SIOP 84, 89, 95 studies – Italian ICG 79, 88, 96 studies – German CWS81, 86, 91, 96 studies.

Results: 29 % of the patients were < 3 year old, 36 % were 3 to 10 year old and 35 % > 10 year old. 350 (63%) patients had alveolar RMS and 116 (22%) had regional nodes.

The overall survival and EFS were 65% and 51% at 5 years respectively and 59% and 48% at 10 years respectively.

By univariate analysis, EFS was influenced by age below 3 years but not by age over 10 years (EFS were 61%, 49% and 46% for patients below 3 years, from 3 to 10 and 10 years or more respectively). It was also influenced by tumor invasiveness, tumor size, lymph node involvement, histology, completeness of surgery at diagnosis and cooperative groups. In multivariate analysis of EFS, size, lymph nodes, quality of surgery, cooperative groups had independent impact. Age and histology had no more impact.

OS (univariate analysis) was influenced by age below 3 years but not by age over 10 years (OS were 77%, 61% and 58% for patients below 3 years, from 3 to 10 and 10 years or more respectively). In multivariate analysis, age, lymph nodes, tumour invasiveness, quality of surgery at diagnosis had independent impact. Histology, tumour size and cooperative groups had no more impact.

Conclusion: This analysis shows that significant cut-point for age is 3 years, that histology per se has no impact on OS and EFS. It also underscores the impact of initial surgery on outcome.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 328 - 328
1 May 2010
Sidhom S Al-Lami M Sturdee S Anderson A Muthukumar N Hughes V Bennett C London N
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Aim: To assess the safety and efficacy of a mini-incision surgical (MIS) approach to knee arthroplasty (TKA) compared to a traditional standard approach.

Background: TKA through less invasive approaches have become increasingly popular in recent years. These range from smaller skin incisions to the ‘quadriceps-sparing’ procedures. Claims of improved recovery time and other clinical/economic advantages have been tempered by concerns about the safety of such procedures. This study was designed to evaluate any potential advantages of a specific approach (MIS) whilst studying peri-operative, radiological and outcome data to examine procedural safety.

Patients and Methods: 80 patients undergoing TKA were randomised to a standard or MIS (mini-midvastus) approach. The latter involved patella subluxation, rather than eversion. The operative, anaesthetic and post-operative treatments were standardised including rehabilitation protocols. Strict discharge criteria were established and independently verified and patients were discharged directly to their homes capable of independent care. Specifically the study evaluated patient demographics, operative time, blood loss and hospital stay. Outcome data including Knee Society Scores, Oxford Knee Scores and SF36 were recorded regularly in the early recovery period and up to 1 year post-operatively. Independent radiological review of implant positioning and alignment was obtained.

Results: There were no significant differences in operative time, blood loss, or other intra-operative data. Accelerated discharge was achieved in both groups (compared to historic data), however the length of stay (LOS) was significantly shorter in the MIS patients (mean – 3.5 days compared with 4.4 days in the standard patients). There was no statistical difference in clinical outcome analyses between the groups.

Discussion: Less invasive approaches to TKA have been reported over recent years but most studies have been anecdotal comparing patient recovery with historic controls which potentially can exaggerate clinical and economic benefits. Concerns have also been raised regarding the safety of these modified procedures. This study demonstrates a reduction in hospital stay and recovery in all patients as a result of accelerated rehabilitation. The MIS patients benefited from an additional significant reduction length of stay compared to controls with no evidence of compromise in terms of safety or efficacy.

Conclusions: This study has demonstrated the safety of the MIS mini-midvastus approach and a clear reduction in hospital length of stay. MIS surgery can offer substantial clinical and economic benefits but procedures must be closely evaluated to ensure equivalent or enhanced outcomes are achieved.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 26 - 26
1 Mar 2010
Tornetta P Siegel J Burke P Kaseje N Agarwal S Soto J Anderson S
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Purpose: In patients with pelvic trauma, the need to quickly and accurately rule out sources of bleeding is paramount. We sought to determine the predictive value of CT angiography in determining the need for therapeutic angiography and to ascertain if definable arterial bleeding correlated with anatomic injury.

Method: Over a 2 year period 58 patients with a high-energy mechanism and pelvic injury underwent pelvic CT angiography as part of their initial trauma CT scan. This was performed as a 25 second delayed scan (after contrast introduction) using a GE light speed VCT64 scanner. The decision to proceed to therapeutic angiography was made on clinical grounds and was later compared with the CT angiographic findings. The anatomic location of bleeding on CT angio and interventional angio were compared.

Results: There were 36 male and 22 female patients, aged 43 (17 – 86), with average ISS of 18.6. The 18 (31%) patients with positive extravasation on CT angiography had higher initial blood requirements compared to those without extravasation. Two of the CT(+) group died prior to therapeutic angiography being performed. 11 of the remaining 16 had interventional angiography; 8 had (+) findings, including 7 major vessels coiled and 1 cutoff vessel observed. 1 patient of 40 with negative CT angiogram met clinical criteria had an interventional angiography; no arterial bleeding was discovered. The negative predictive value of CT angiography for pelvic arterial bleeding requiring therapeutic angiography was 100%; the positive predictive value of angiographically treatable bleeding was 70% (counting the two early deaths). The vessel location on CT angio and therapeutic angio was consistent in all cases. The CT angio (+) group had a higher percentage of unstable pelvic injuries (67% vs. 40%).

Conclusion: In this pilot study, CT angiography added to the initial trauma scan in patients with pelvic trauma demonstrated a 100% NPV for arterial bleeding that required therapeutic angiography on clinical grounds. Positive findings correlated well with the anatomic location of pelvic injury and had a 70% PPV for angio-graphically treatable bleeding. Further study of this technique is warranted.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 202 - 202
1 Mar 2010
Anderson I Shim V Pitto R Malcolm D Mithraratne K Hunter P
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Patient- specific orthopaedic models are currently used in computer navigation. They provide realistic 3-D geometries for assessment of device placement (e.g. tibial trays, hip implants). Models are generated at time of operation by the surgeon. But patient-specific models have other uses. We envisage a future in which realistic 3-D patient models are routinely used for predicting the outcome of surgical procedures and new devices and for general patient health monitoring.

We are currently developing accurate 3-D models directly from CT scan post-operation. They are being used in investigations of the progress of bone remodeling. Such work can provide valuable feedback on the outcome of new procedures and how bone remodels under load. Such models would eventually include other tissue such as muscles and skin.

But there are a number of research and development challenges associated with the creation of patient-specific models. They include

minimal use of radiation for data collection;

need for an automated method of generating patient specific models as clinicians (not engineers) should be able to create computer models easily and quickly;

need for improvements in computational efficiency. An ultimate goal would be to run simulations on computer hardware that is available to the clinician;

How to deal with missing data. We need techniques for supplementing patient data with data from a “model library”;

Research to provide techniques for dealing with multiple organs (muscles, skin and bone altogether).

We are working to meet these challenges. They include the use of generic data to supplement patient data, efficient ways of morphing models to fit the patient, and multi-scale modeling strategies. Work in progress at the Auckland Bio-engineering Institute will be presented in this talk.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 35 - 35
1 Mar 2010
Anderson SL Taillon MR Ernst M
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Purpose: 2 orthopaedic surgeons identified 18 patients who developed glenohumeral chondrolysis following arthroscopic shoulder surgery. The index surgery for all 18 patients occurred over an 18 month period. We sought to find any common factors among the 18 cases.

Method: A retrospective chart review of all 18 patients was performed. We gathered information on patient demographics, type of surgical procedure, nature of shoulder instability, post-operative complications such as infection, the use of radiofrequency energy, the type/number of suture anchors, the use of an IAPPC and the type of local anaesthetic used. We compared pre-operative radiographs and MRI scans to the intra-operative findings from the operative report to confirm that no chondrolysis was present pre-operatively. We examined post-operative radiographs and MRI scans to document the extent of chondrolysis

Results: Of the 18 patients who developed chondrolysis, we had 15 males and 3 females with an average age of 23 years (range 16–39). 17 patients had shoulder instability due to a definitive traumatic event while 1 patient had an atraumatic etiology. No radiofrequency energy was used in any of the cases. No post-operative infections were diagnosed and many had work-ups for infection which included ESR, CRP, bone & gallium/WBC scans. All patients had labral stabilization procedures, 15 anterior (Bankart), 1 posterior, and 2 combinations. All patients received suture anchors, 13 patients had 2 anchors and 5 had 3 anchors. 2 different manufacturer’s suture anchors were used, 10 patients received Smith & Nephew anchors while 8 patients received Linvatec anchors. 10 patients received bioabsorbable anchors and 8 patients received metal anchors. All patients received an IAPPC loaded with 0.5% bupivacaine with epinephrine for post-operative pain control. 15 of the IAPPC’s were considered large with an infusion rate of 5 mL/hr and a fill volume of 275 mL’s. 3 IAPPC’s were considered small with an infusion rate of 2 mL/hr and a fill volume of 100 mL’s.

Conclusion: We suspect a continuous intra-articular infusion of bupivacaine with epinephrine may have contributed to the development of chondrolysis. We caution against the use of IAPPC’s until their safety has been proven.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 19 - 20
1 Mar 2010
Jones CB Sietsema DL Henning JA Anderson JG Bohay DR
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Purpose: To evaluate the functional outcome of operatively treated Lisfranc injuries.

Method: Over a 7-year interval from 1998 to 2005, 184 skeletally mature patients were identified retrospectively with operatively treated Lisfranc injuries. 85 patients had prospectively measured SMFA functional outcomes and satisfaction surveys. The gender was 37 males and 48 females. Mean age was 39 years (range 17–93).

Results: The mechanism was fall (31), MVA (24), crush (15), equestrian (5), or twisting (10). Patients were operatively treated with open reduction internal fixation (ORIF, 53) or primary arthrodesis (PA, 32). The SMFA reliability for this patient sample was 0.892. The function and bother outcomes were 19.4 and 15.8, respectively. The function (21.5 vs. 16.0, p=.11) and bother (17.5 vs. 13.0, p=.25) outcomes were not significantly different for ORIF vs. PA, respectively. In the ORIF group, HW removal (40 of 53) performed better than HW retention (13 of 53) with outcome bother but not function measures of (14.7 vs. 26.1, p< 0.05).

Conclusion: If performed well, either ORIF or PA technique function well. Patients are more satisfied with the results and appearance of PA over ORIF. HW removal compared to HW retention positively affect bother not function measures. Secondary surgeries negatively affect both bother and function measures. Patients with pain, associated foot or polytrauma injuries function worse.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 228 - 228
1 Mar 2010
Singh A Anderson G
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Intramedullary nailing is acknowledged as a safe and effective mode of treatment for many tibial fractures. Implant removal is frequently indicated either as an elective procedure following union or because of problems such as infection or delayed fracture union. It is therefore essential that intramedullary rod removal should be reasonably straightforward and atraumatic.

We describe three cases in which bony growth into the implant has made rod removal either difficult or impossible. We include photographs of two removed implants with clearly visible areas of osseo-integration with bony growth into the cannulation through the interlocking holes as well as radiographs demonstrating the same phenomenon.

The average time between insertion and removal was 16 months. In all cases an end cap had been used such that insertion of the extraction device was straightforward but for two patients nail removal was extremely difficult due to bone ingrowth and in the third patient the nail had to be left in-situ. All three implants were made of titanium and the patients were all active young males. The authors have never encountered this problem with steel rods and speculate that the osteointegrative property of titanium is the major causative factor.

We suggest that unremoved intramedullary rods represent a major risk in fracture management and that close monitoring of these implants should be undertaken.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 166 - 166
1 Mar 2010
Clarke I Lazennec Y Cattonne Y Kubo K Anderson I McPherson E Donaldson T
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FDA approval of metal-on-metal (MOM: 28, 32mm) bearings has provided 10 years of clinical experiences in USA. However there has been no detailed mapping of wear phenomena in retrieval cases. We present an analysis of 28 cases, MOM retrievals with 1 to 10 years follow-up, radiographic reviews and metal ion studies. Ball diameters ranged from 28mm to 42mm. Two balls were the early design with skirts. Main indicators for revision were the progressive radiographic changes indicative of osteolysis, with associated hip pain. Approximately 54% of patients were males and ages ranged from 36 to 76 years of age. Only 7 femoral stems were recovered but all had impingement marks. Only three cases lacked any evidence of stripe wear and these were in very elderly patients. Approximately 85% of these cases showed some evidence of stripe wear and multiple stripes were clearly visible on 50% of the femoral balls. The medial ball stripes were twice as common as lateral. Stripe wear was identified in 25% of CoCr liners.

In the hip simulator studies generally show ‘run-in’ wear rates of 1–7mm3 per million cycles (Mc). We noted that above the 5mm3/Mc threshold, the serum generally appeared black. In contrast, the ‘steady-state’ wear rates of 0.1–1.6 mm3/Mc showed the true potential of MOM bearings. However there were often examples of higher wear (7–20 mm3/Mc), which gave confounding trends in published studies. Our studies of metal ions in the simulator lubricant provided a very accurate representation of MOM wear.

There are many limitations in comparing in-vitro to in-vivo wear performance. Our retrieval data are biased to cases that failed due to hip pain, had radiographic signs of progressive osteolysis and some showed high levels of metal ions. There was also the bias of having predominantly a CoCr sandwich design (polyethylene adaptor). Use of the small ball added the well-known risks of impingement, subluxation and dislocation with rigid cups. Using the ‘damage modes’ from McKellop, we found only normal Mode-1 wear to be rare in these cases, whereas Modes# 2–4 had an incidence approaching 30% each. Signs of impingement were evident in 85% of our cases. Thus summarizing these MOM wear phenomena in retrieved 28mm sandwich cups, the evidence implicated impingement and 3rd-body wear modes (#2–4) as the clinical risk for adverse wear effects at 10 years follow-up. The in-vitro wear studies have not yet simulated such adverse clinical effects.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 154 - 154
1 Mar 2010
Clarke I Kubo K Lazennec Y Cattonne Y Anderson I Smith E Turnbull A Donaldson T
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From 1985 metal-on-metal (MOM) designs of resurfacing (RSA) and total hip arthroplasties (THR) have been available over a large diameter range (28–60mm). In-vitro studies indicated satisfactory low wear performance for all designs and diameters tested (wear = 0.1 to 7 mm3). While reports from many centers have been encouraging, some have reported adverse effects. We reviewed clinical and metal ion studies in large diameter retrievals and compared these to 28mm MOM cases. Patients with the latter THR ranged 36–76 years of age and were followed 9–11 years. Main finding in our revisions was osteolysis and pain. The 28mm ball was represented 86% of cases; 71% balls had stripe wear. For liners, 25% had circumferential stripe wear and impingement was evident in 64% cases. Seven cemented stems were recovered with impingement marks; 26 stems were undamaged and therefore not revised. Using the concept of ‘damage modes’ from McKellop, normal wear mode #1 was evident in only 14% of 28mm retrievals whereas incidence of ‘abnormal’ modes #2-4 approached 30% each. Thus the 28mm MOM appeared susceptible to impingement risks with CoCr liners. Summarizing MOM retrievals, damage modes 2–4 were most likely implicated in revisions. The performance of such ‘small diameter’ THRs will be contrasted to our large diameter THR and RSA experience. The questions to be reviewed include, how much of the reported MOM adversity was predictable and how much risk was due to

wear of small diameter MOM,

adverse cup positioning and hip instability,

cup-stem impingement issues or

design conformity issues?


The Journal of Bone & Joint Surgery British Volume
Vol. 92-B, Issue 2 | Pages 230 - 234
1 Feb 2010
Anderson GA Thomas BP Pallapati SCR

Inability to actively supinate the forearm makes common activities of daily living and certain vocational activities awkward or impossible to perform. A total of 11 patients with deficient supination of the arm underwent transfer of the tendon of flexor carpi ulnaris to the split tendon of brachioradialis with its bony insertion into the radial styloid left intact. Active supination beyond neutral rotation was a mean of 37.2° (25° to 49.5°) at a minimum follow-up of three years, representing a significant improvement (95% confidence interval 25 to 50, p < 0.001). Functional evaluation of the hand after this transfer showed excellent and good results in ten patients and fair in one.

The split tendon of brachioradialis as an insertion for transfer of the flexor carpi ulnaris appears to provide adequate supination of the forearm without altering the available pronation and avoids the domination of wrist extension sometimes associated with transfers of the flexor carpi ulnaris to the radial extensors of the wrist.