Soft tissue reactions following metal-on-metal arthroplasty of the hip have been under discussion in recent times. The phenomenon has been observed since the advent of arthroplasty, but the particular nature of metal-on-metal (MoM) resurfacing or total hip arthroplasty (THA), and the associated shedding of metal particles in high wear states, appears to excite a more aggressive response. Recent reports suggest involvement of muscle groups on a wide scale, and some cases of neurovascular involvement. It is not known which reactions require widespread muscle excision, and which cases may be adequately addressed by bearing exchange alone. We report three cases of soft tissue reaction (pseudotumour) following MoM hip resurfacing all managed with revision to ceramic-on-ceramic (CoC) THA with minimal soft tissue excision. All patients were female with ages at original operation of 49, 52 and 58 years. Time to revision surgery was 85, 28 and 66 months respectively. Prosthesis revision resulted in progressive and satisfactory resolution of the pseudotumour. We propose that in the early stages, pseudotumour following MoM hip resurfacing can be adequately managed with revision to ceramic-bearing THA with minimal soft tissue excision, rather than revision with extensive soft tissue debridement that has been recently described.
Manual templating using transparencies allows preoperative visualisation of anatomy and prosthesis size, as well as ease of exchange from prosthesis type to another. Most UK hospitals have converted X-ray provision to Picture Archiving and Communication Systems (PACS), necessitating the use of digital templating. We assessed the accuracy and speed of templating for hip replacement on 36 occasions in 12 patients listed for hip replacement, using final component choice as an indicator of accuracy. Each hip was templated using, “Orthoview,” templating programme
without initial scaling and following scaling and then manually scaled images on a computer screen superimposing acetate templates in the traditional fashion. A two pence coin taped to the lateral aspect of the thigh at the level of the greater trochanter was used for scaling purposes. Our results showed acetate templating to be most accurate, correlating identically with the prosthesis stem size in 9/12 cases, and with the acetabulum reamed size on 10/12 occasions. Acetate templating was also the most accurate method when allowing for +/− one size difference, being within +/− one size in all 12/12 cases for both stem size and acetabulum size. In comparison, both scaled and non scaled Orthoview templating correlated with the correct femoral prosthesis size in 5/12 patients. The acetabulum ream size was correctly templated in 10/12 patients using unscaled Orthoview, and 8/12 patients using scaled Orthoview. Additionally, Orthoview templating took a mean of 6 minutes, whereas manual templating can be achieved in under 30 seconds. Manual templating of scaled PACS images using transparencies conferred considerable advantages in terms of accuracy and speed. Moreover, this method allows a hands-on assessment of the forthcoming surgical procedure immediately prior to the operation, as well as late changes in implant choice. We recommend the continuation of manual templating using modern scaled digital images.
To assess the outcome of knee “arthrodesis” using cemented Endo-Model knee fusion nail in failed Total Knee Replacement (TKR) with significant bone loss due to infection. This is a retrospective case study of seven patients with infected TKR and multiple surgeries with significant bone loss. All patients had antibiotic loaded cement with a temporary K-nail as a first stage procedure to eradicate infection. All seven patients had “arthrodesis” performed using cemented modular Endo-Model Knee Fusion nail (Waldemar Link, Hamburg) by the senior author. Cement was used to hold the stems in the diaphyses and not used around the coupling mechanism. The “arthrodesis” relied entirely on the coupling mechanism which has been shown to have good axial and torsional rigidity by mechanical testing. Outcome was assessed using pre and post Visual Analogue Score (VAS). Mean age was 72.3 years(62–86). Mean follow up was 39.6 months (7–68). The VAS pain score improved from pre-operative mean score of 7.9 to a postoperative score of 1.5. One patient suffered fracture of femoral cement mantle at 50 months who underwent a technically easy exchange revision. One patient had recurrent infection with distal femoral fracture at 36 months and was revised to distal femoral replacement. The Endo-Model knee arthrodesis nail restores limb lengths, has good early results in terms of pain relief and provides a stable knee “arthrodesis” in cases where there is significant bone loss and extensor mechanism insufficiency following an infected TKR.
Data was analysed for both inter-observer and test-retest reliability using the intra-class correlation coefficient and the Bland-Altman method (use of two methods provides a better estimation of accuracy).
Hip resurfacing is a relatively new concept in hip arthroplasty, but is being performed more frequently in the United Kingdom. We compared anteroposterior radiographs of 30 patients who had undergone cemented hip resurfacing (Cormet) with those of 30 patients who had undergone uncemented hip resurfacing (Cormet). All operations were performed using the anterolateral approach. We measured the acetabular offset, femoral offset, stem shaft angle, medialisation of the cup, head/neck ratio, cup height, leg length, and the implant seating pre-operatively, immediately postoperatively and one year postoperatively. The data were analysed by paired t-tests. There were no significant differences between any of the measurements at all three time periods. This demonstrates no loss of offset, no femoral neck thinning and no leg length reduction. We note a smaller femoral offset and a reduction on average of 2mm in seating of the femoral implant in the uncemented group as compared to the cemented group. This we attribute to movement of the femoral implant in the first year post-operatively, and as such restoration of the femoral offset to the pre-operative level. We conclude that uncemented hip resurfacing does not show any statistical benefit over cemented hip resurfacing, although we did observe a more accurate reproducible femoral offset with better seating of the implant in the uncemented group. We also note that there was no neck thinning in any of these patients at one year post-operatively.
The treatment of bony defects of the tibia at the time of revision total knee replacement is controversial. The place of compacted morsellised bone graft is becoming established, particularly in contained defects. It has previously been shown that the initial stability of impaction-grafted trays in the contained defects is equivalent to that of an uncemented primary knee replacement. However, there is little biomechanical evidence on which to base a decision in the treatment of uncontained defects. We undertook a laboratory-based biomechanical study comparing three methods of graft containment in segmental medial tibial defects and compared them with the use of a modular metal augment to bypass the defect. Using resin models of the proximal tibia with medial defects representing either 46% or 65% of the medial cortical rim, repair of the defect was accomplished using mesh, cement or a novel bag technique, after which impaction bone grafting was used to fill the contained defects and a tibial component was cemented in place. As a control, a cemented tibial component with modular metal augments was used in identical defects. All specimens were submitted to cyclical mechanical loading, during which cyclical and permanent tray displacement were determined. The results showed satisfactory stability with all the techniques except the bone bag method. Using metal augments gave the highest initial stability, but obviously lacked any potential for bone restoration.
The aims of this study were
to develop the Roche lightcycler Staphylococcal and Enterococcal PCR kits to facilitate diagnosis of hip and knee prosthetic infections To analyse results together with bacteriological and histological findings.
29 patients had non-inflammatory arthritis. 14/18 (77.8%) with positive cultures had staphylococci +/or enterococci isolated and 10 PCR results correlated. The other 11 patients had negative cultures. 9 patients had inflammatory arthritis. Six were culture negative and of the other three, 2 were positive for staphylococci on culture with 1 positive by PCR.
Enterococcal PCR confirmed culture positivity in 2/3 patients. An additional 5 positive PCR’s were obtained from patients’ culture negative for enterococci. It is not clear if these are false positives or more sensitive detection of enterococcal isolation.
Restoration of hip biomechanics is an important determinant of outcome in hip replacement. Pre-operative templating is considered important in preoperative planning, and this trend is likely to develop further to satisfy consumer demand and to facilitate navigated surgery, particularly as digitisation of radiographs becomes established. We aimed to establish how closely natural femoral offset could be reproduced using the manufacturers’ templates for 10 femoral stems in common use in the U.K. The most frequently used femoral components from the U.K. national joint registry and uncemented) were identified, and the CPS-Plus stem was added, as this is in use in our unit. A series of 24 consecutive pre-operative radiographs from patients who had undergone unilateral total hip replacement for unilateral osteoarthritis of the hip were reviewed. The non-operated on side of the pelvic radiographs was templated as described by Schmalzreid. 3 surgeons of variable experience (junior trainee, senior trainee, consultant) performed the assessment. The standard deviation of change in offset between the templated centre of rotation and the normal centre of rotation of the set of radiographs for each prosthesis was then calculated allowing a ranking. The most accurate template was the CPS with a mean standard deviation of 1.92mm followed in rank order by: CPT 2.21mm, C Stem 2.42mm, Stanmore 3.02 mm Exeter 3.06 mm, ABG II 3.54mm, Charnley 3.54 mm, Corail 3.63 mm, Furlong HAC 4.2 mm and Furlong modular 4.86mm. There is wide variation in the ability of the femoral templates to reproduce normal femoral anatomy in a series of standard pre-operative hip radiographs. The more modern cemented polished tapered stems with high modularity appear best able to reproduce femoral offset. Nevertheless, some older monoblock stems, despite poor templating characteristics, are known to be associated with acceptable clinical results. The coming years are likely to be witness to changes in patient expectations and radiograph storage. Implant design and digital templates will need to improve apace with these changes, to ensure accurate preoperative planning.
Cemented, polished, tapered stems have produced excellent results, but some early failures occur in younger patients. The CPS-Plus stem (Plus Orthopedics AG, Switzerland) is a polished double taper with rectangular cross section for improved rotational stability. A unique proximal stem centraliser increases cement pressurisation, assists alignment and creates an even cement mantle. Radiostereometric analysis has demonstrated linear subsidence in a vertical plane, without any rotation or tilt. These features should improve implant durability. Midterm (5 years) results of a prospective international multicentre study are presented.
The mean Harris hip score improved from 42 preoperatively to 91. There have been no revisions for aseptic loosening and none of the stems have radiographic evidence of loosening. There has been one revision for deep sepsis. With revision for aseptic loosening as an endpoint, stem survivorship is 100%.
The visco-elastic behaviour of acrylic bone cement is a key feature of cement-implant performance. The ability of the cement to creep in conjunction with a force-closed design of stem (collarless polished taper) affords protection of the vital bone-cement interface. Most surgeons in the UK use antibiotic-laden PMMA in primary total joint arthroplasty. In revision surgery the use of bespoke antibiotic-cement combinations is common. The aim of this study was to elicit the effect of antibiotics upon the physical properties of bone cement.
The cements used were Palacos R40 and Palacos R with gentamicin. The antibiotics added included fucidin, erythromycin, teicoplanin and vancomycin in 500mg powder aliquots up to a maximum of 1g per 40 g mix. All data were analysed using ANOVA with Bonfer-roni post-hoc test. Pearson’s correlation coefficient was used to investigate the association between physical factors (SPSS).
The visco-elastic behaviour of cement, is a key feature of cement-implant performance in total hip arthroplasty. The aim of this study was to describe the creep behaviour of the leading plain bone cements under standardised physiological in-vitro conditions.
The cements tested were Palacos R, CMW1 and Smartset GHV and Surgical Simplex P. All data were analysed using ANOVA with Bonfer-roni post-hoc test (SPSS).