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Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_6 | Pages 129 - 129
1 Jul 2020
Petruccelli D Wood T Winemaker MJ De Beer J
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Overall, hip and knee total joint replacement (TJR) patients experience marked benefit, with reported satisfaction rates of greater than 80% with regard to pain relief and improved function. However, many patients experience ‘nuisance’ symptoms, an annoyance which may cause discomfort, which can negatively impact postoperative satisfaction. The purpose of this study was to evaluate the prevalence of nuisance symptoms among TJR patients and impact on overall patient satisfaction.

A prospective survey study to assess type and prevalence of primary hip/knee TJR related nuisance symptoms, and impact on patient satisfaction at six-months to one-year post-TJR was conducted. The survey was administered over a one-year period at one academic arthroplasty centre. Survey questions tapped occurrence of commonly reported nuisance symptoms (e.g. localized pain, swelling, stability, incision appearance/numbness, stiffness, clicking/noise, ability to perform activities of daily living), and impact of the symptom on overall hip/knee satisfaction rated on a 10-point visual analogue scale (VAS), (0=no impact, 10=to a great extent). Overall VAS satisfaction with TJR was also assessed (0=not at all satisfied, 10=extremely satisfied). Survey responses were analysed using descriptive statistics.

The sample comprised of 974 primary TJR patients, including 590 knees (61%) and 384 hips 39%) who underwent surgery over a one-year period. Among knees, the most commonly reported nuisance symptoms and associated impact to satisfaction per mean VAS scores included: difficulty kneeling (78.2%, mean VAS 4.3, ±3.3), limited ability to run or jump (71.6%, VAS 3.3, ±3.3), numbness around incision (46.3%, VAS 3.8, ±3.3), clicking/noise from the knee (44.2%, VAS 2.7, ±2.7) and stiffness (43.3%, 3.3, ±2.7) following knee arthroplasty. Overall, 88.1% of knee patients surveyed experienced at least one self-reported nuisance symptom at one-year postoperative. Mean overall VAS satisfaction with knee TJR was reported as 9/10 (±1.7). Among hip TJR patients, the most commonly reported nuisance symptoms and associated impact to satisfaction per VAS scores were: limited ability to run or jump (68.6%, VAS 3.4, ±3.4), muscular pain in the thigh (44.8%, VAS 3 ±2.7), limp when walking (37.6%, VAS 4.1, ±3.2), hip stiffness (31%, VAS 3.1, ±2.4), and new or worsening low back pain (24.3%, VAS 2.9, ±2.5). Overall, 93.7% of patients experienced at least one self-reported nuisance symptom at one-year postoperative. Mean overall VAS satisfaction following total hip arthroplasty at one year was reported as 8.9/10 (±1.7).

Nuisance symptoms following primary total hip and knee arthroplasty are very common. Despite the high prevalence of such symptoms, impact of individual symptoms to overall TJR satisfaction is minimal and overall TJR patient satisfaction remains high. Careful preoperative counselling regarding the prevalence of such symptoms is prudent and will help establish realistic expectations following primary hip and knee TJR.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_7 | Pages 9 - 9
1 Jul 2020
Rampersaud RY Perruccio A Yip C Power JD Canizares M Badley E Lewis SJ
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Up to one-third of patients experience limited benefit following surgical intervention for LS-OA. Thus, identifying contributing factors to this is important. People with OA often have multijoint involvement, yet this has received limited attention in this population. We documented the occurrence and evaluated the influence of multijoint symptoms on outcome following surgery for LS-OA.

141 patients undergoing decompression surgery+/−fusion for LS-OA completed the Oswestry Disability Index (ODI) pre- and 12-months post-surgery. Also captured pre-surgery: age, sex, education, BMI, smoking, depressive symptoms and comorbidities. Any joints with “pain/stiffness/swelling most days of the month” were indicated on a homunculus. A symptomatic joint site count (e.g. one/both knees= one site), excluding the back, was derived (range zero to nine) and considered as a predictor of magnitude of ODI change, and likelihood of achieving minimally clinically important improvement in ODI (MCID=12.8) using multivariable adjusted linear and log-Poisson regression analyses.

Mean age: 66 years (range:42–90), 46% female. 76% reported one+ joint site other than the back, 43% reported three+, and nearly 10% reported six+. (< MCID) for those with three sites, and four units for those with six+ sites. Associated with a greater likelihood of not achieving MCID were increasing joint count (11% increase per site (p=0.012)), higher BMI, current/former smoker, and worse baseline ODI tertile.

Results suggest there is more than just the back to consider to understand patient-reported back outcomes. Multijoint symptoms directly contribute to disability, but there is potential they may contribute to systemic, largely inflammatory, effects in OA as well.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_III | Pages 36 - 36
1 Feb 2012
Snow M Cheong D Funk L
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Aims

To determine whether a correlation exists between the clinical symptoms and signs of impingement, and the severity of the lesions seen at bursoscopy.

Methods

Fifty-five consecutive patients who underwent arthroscopic subacromial decompression were analysed. Pre-operatively patients completed an assessment form consisting of visual analogue pain score, and shoulder satisfaction. The degree of clinical impingement was also recorded. At arthroscopy impingement was classified according to the Copeland-Levy classification. Clinical assessment and scoring was performed at 6 months post-operatively. Linear regression coefficients were calculated to determine if the degree of impingement at arthroscopy correlated with pre-operative pain, satisfaction and clinical signs of impingement.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_1 | Pages 144 - 144
1 Jan 2016
Furu M Ishikawa M Kuriyama S Nakamura S Azukizawa M Hamamoto Y Ito H Matsuda S
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Purpose

Total knee arthroplasty (TKA) is one of the most successful surgeries with respect to relieving pain and restoring function of the knee. However, some studies have reported that patients are not always satisfied with their results after TKA. The aim of this study was to determine which factors contribute to patient's satisfaction after TKA.

Methods

We evaluated 69 patients who had undergone 76 primary TKAs between March 2012 and June 2013, and assessed patient- and physician- reported scores using the 2011 Knee Society Scoring System and clinical variables before and after TKAs. We determined the correlation between patient satisfaction and clinical variables.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_3 | Pages 94 - 94
1 Jan 2016
Osadebe U Brekke A Ismaily S Loya-Bodiford K Gonzalez J Stocks G Mathis KB Noble P
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Background

With the rising demand for primary total hip arthroplasty (THA), there has been an emphasis on reducing the revision burden and improving patient outcomes. Although studies have shown that primary THA effectively minimizes pain and restores normal hip function for activities of daily living, many younger patients want to participate in more demanding activities after their operation. The purpose of this study was to examine the relationship between age, gender and patient satisfaction after total hip arthroplasty.

Methods

With IRB approval, 2 groups of subjects were enrolled in this study: (i) 143 patients at an average of 25 months (range 10–69 months) post-primary THA, and (ii) 165 control subjects with no history of hip surgery or hip pathology. All subjects were assigned to one of four categories according to their age and gender: Group A: 40–60 year old males (31 THA; 42 Controls), Group B: 40–60 year old females (25 THA; 53 Controls), Group C: 60–80 year old males (35 THA; 25 Controls), and Group D: 60–80 year old females (36 THA; 23 Controls). Each patient completed a self-administered Hip Function Questionnaire (HFQ) which assessed each subject's satisfaction, expectations, symptoms and ability to perform a series of 94 exercise, recreational and daily living activities. These included participation in work-out activities, adventure and water sports, running and biking, and contact and team sports. Each participant was also asked their activity frequency, symptom prevalence and satisfaction with their hip in performing each activity.


The bone-patellar tendon-bone (BTB) autograft is associated with difficulty kneeling following anterior cruciate ligament (ACL) reconstruction, however it is unclear whether it results in a more painful or symptomatic knee when compared to the hamstring tendon autograft. This study aimed to identify the rate of significant knee pain and difficulty kneeling following primary ACL reconstruction and clarify whether graft type influences the risk of these complications. Primary ACL reconstructions prospectively recorded in the New Zealand ACL Registry between April 2014 and November 2019 were analyzed. The Knee Injury and Osteoarthritis Outcome Score (KOOS) was analyzed to identify patients who reported significant knee pain, defined as a KOOS Pain subscale score of ≤72 points, and kneeling difficulty, defined as a patient who reported “severe” or “extreme” difficulty when they kneel. The rate of knee pain and kneeling difficulty was compared between graft types via univariate Chi-square test and multivariate binary logistic regression with adjustment for patient demographics. 4492 primary ACL reconstructions were analyzed. At 2-year follow-up, 9.3% of patients reported significant knee pain (420/4492) and 12.0% reported difficulty with kneeling (537/4492). Patients with a BTB autograft reported a higher rate of kneeling difficulty compared to patients with a hamstring tendon autograft (21.3% versus 9.4%, adjusted odds ratio = 3.12, p<0.001). There was no difference between graft types in the rate of significant knee pain (9.9% versus 9.2%, p = 0.49) or when comparing absolute values of the KOOS Pain (mean score for BTB = 88.7 versus 89.0, p = 0.37) and KOOS Symptoms subscales (mean score for BTB = 82.5 versus 82.1, p = 0.49). The BTB autograft is a risk factor for post-operative kneeling difficulty, but it does not result in a more painful or symptomatic knee when compared to the hamstring tendon autograft


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_13 | Pages 64 - 64
1 Dec 2022
Orloff LE Carsen S Imbeault P Benoit D
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Anterior cruciate ligament (ACL) injuries have been increasing, especially amongst adolescents. These injuries can increase the risk for early-onset knee osteoarthritis (OA). The consequences of late-stage knee OA include structural joint change, functional limitations and persistent pain. Interleukin-6 (IL-6) is a pro-inflammatory biomarker reflecting knee joint healing, and increasing evidence suggests that IL-6 may play a critical role in the development of pathological pain. The purpose of this study was to determine the relationship between subjective knee joint pain and function, and synovial fluid concentrations of the pro-inflammatory cytokine IL-6, in adolescents undergoing anterior cruciate ligament reconstruction surgery. Seven youth (12-17 yrs.) undergoing anterior cruciate ligament (ACL) reconstruction surgery participated in this study. They completed the Pedi International Knee Documentation Committee (Pedi-IKDC) questionnaire on knee joint pain and function. At the time of their ACL reconstruction surgery, synovial fluid samples were collected through aspiration to dryness with a syringe without saline flushing. IL-6 levels in synovial fluid (sf) were measured using enzyme linked immunosorbent assay. Spearman's rho correlation coefficient was used to determine the correlation between IL-6 levels and scores from the Pedi-IKDC questionnaire. There was a statistically significant correlation between sfIL-6 levels and the Pedi-IKDC Symptoms score (-.929, p=0.003). The correlations between sfIL-6 and Pedi-IKDC activity score (.546, p = .234) and between sfIL-6 and total Pedi-IKDC score (-.536, p = .215) were not statistically significant. This is the first study to evaluate IL-6 as a biomarker of knee joint healing in an adolescent population, reported a very strong correlation (-.929, p=0.003) between IL-6 in knee joint synovial fluid and a subjective questionnaire on knee joint pain. These findings provide preliminary scientific evidence regarding the relationship between knee joint pain, as determined by a validated questionnaire and the inflammatory and healing status of the patient's knee. This study provides a basis and justification for future longitudinal research on biomarkers of knee joint healing in patients throughout their recovery and rehabilitation process. Incorporating physiological and psychosocial variables to current return-to-activity (RTA) criteria has the potential to improve decision making for adolescents following ACL reconstruction to reduce premature RTA thereby reducing the risk of re-injury and risk of early-onset knee OA in adolescents


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_6 | Pages 14 - 14
1 Apr 2018
Kreuzer S Malanka S Dettmer M Pourmoghaddam A Veverka M
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Background. Total Hip Arthroplasty (THA) has long been the standard treatment for cases in which non-surgical alternatives have failed to improve pain and function in hip osteoarthritis (OA) patients. Outcomes from THA have improved over time with better surgical techniques and improved implant designs. While conventional neck-sacrificing implants have been associated with favorable outcomes, there is evidence to suggest biomechanical advantages of newer, femoral neck-preserving short-stem implants, including the Corin MiniHip. However, there is a still a gap of knowledge regarding the potential benefits of the MiniHip stem over conventional neck-sacrificing stems in regards to patient-reported outcomes (PROs). In this study, we investigated the differences between a neck-sacrificing stem design and neck-preserving short-stem design (MiniHip, Corin Inc.) arthroplasty concerning PROs, and considering the known features of the short stem design, we hypothesized that MiniHip THA would be associated with improved PROs in comparison to a neck-sacrificing implant system. We further sought to investigate gender effects related to MiniHip or conventional stem surgery. Methods. Neck-sacrificing implant patients (n=90, age 57±7.9 years, female=58, male=32) and a matched (matching criteria: follow-up period, BMI, age) cohort group of MiniHip patients (n=105, age 55.16±9.88 years, female: 25, male: 80) reported both pre-operative and post-operative Hip disability and Osteoarthritis Outcome Scores (HOOS) at a minimum interval of 6 months post-operatively and up to three years postoperatively. We applied MANCOVA analysis to compare patient-reported outcome subscores from each group using follow-up period as a covariate and employing gender as an additional grouping factor to evaluate gender effects. Statistical significance was set at α=0.05 and Bonferroni corrections were applied to account for multiple comparisons. Results. There was a main effect of time, showing that all HOOS subscores of both groups increased significantly after surgery (p<0.001). There was a main effect of surgery for subscores Symptoms (p=0.038), ADL (p=0.046), and Sports and Recreation (p=0.039). There was a gender effect only for the subscore Symptoms (p=0.007). There were significant time by surgery interactions for HOOS subscores Symptoms (p=0.002), Pain (p=.009), Sports and Recreation (p=0.004), and QOL (p<0.001) subscores. We also observed a significant time by gender interaction effect for all HOOS subscores (p<0.001). Discussion. The interaction effects regarding most HOOS subscores and surgery/implant type indicate an advantage of MiniHip surgery regarding post-operative reported outcomes. The observed results may be due to previously described improved physiological loading and native hip structure preservation with neck-preserving short-stem designs. While longer-term studies are required for further investigation, evidence suggests the MiniHip may provide a significant benefit to primary THA patients. The additional gender/time interaction effect observed in our study highlights the necessity to consider potential sex differences regarding both the potential/expected improvement in PROs from THA and the requirement to account for such differences when designing osteoarthritis outcome studies based on PROs


Bone & Joint Open
Vol. 1, Issue 7 | Pages 330 - 338
3 Jul 2020
Ajayi B Trompeter A Arnander M Sedgwick P Lui DF

Aims. The first death in the UK caused by COVID-19 occurred on 5 March 2020. We aim to describe the clinical characteristics and outcomes of major trauma and orthopaedic patients admitted in the early COVID-19 era. Methods. A prospective trauma registry was reviewed at a Level 1 Major Trauma Centre. We divided patients into Group A, 40 days prior to 5 March 2020, and into Group B, 40 days after. Results. A total of 657 consecutive trauma and orthopaedic patients were identified with a mean age of 55 years (8 to 98; standard deviation (SD) 22.52) and 393 (59.8%) were males. In all, 344 (approximately 50%) of admissions were major trauma. Group A had 421 patients, decreasing to 236 patients in Group B (36%). Mechanism of injury (MOI) was commonly a fall in 351 (52.4%) patients, but road traffic accidents (RTAs) increased from 56 (13.3%) in group A to 51 (21.6%) in group B (p = 0.030). ICU admissions decreased from 26 (6.2%) in group A to 5 (2.1%) in group B. Overall, 39 patients tested positive for COVID-19 with mean age of 73 years (28 to 98; SD 17.99) and 22 (56.4%) males. Common symptoms were dyspnoea, dry cough, and pyrexia. Of these patients, 27 (69.2%) were nosocomial infections and two (5.1%) of these patients required intensive care unit (ICU) admission with 8/39 mortality (20.5%). Of the patients who died, 50% were older and had underlying comorbidities (hypertension and cardiovascular disease, dementia, arthritis). Conclusion. Trauma admissions decreased in the lockdown phase with an increased incidence of RTAs. Nosocomial infection was common in 27 (69.2%) of those with COVID-19. Symptoms and comorbidities were consistent with previous reports with noted inclusion of dementia and arthritis. The mortality rate of trauma and COVID-19 was 20.5%, mainly in octogenarians, and COVID-19 surgical mortality was 15.4%. Cite this article: Bone Joint Open 2020;1-7:330–338


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_8 | Pages 65 - 65
1 May 2019
Ries M
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Instability after TKA can result from ligament imbalance, attenuation of soft tissues, or ligament disruption. Flexion instability has been reported after both CR and PS TKA. However, the clinical manifestations of flexion instability can be quite variable. Symptoms of flexion instability include pain and swelling after activity. Bracing occasionally can be helpful. Revision options to treat flexion instability include tibial insert exchange and revision to increase constraint. However, more favorable results have been reported using implants with varus-valgus constraint. Constrained mechanisms include a varus-valgus constrained PS post or hinge. The constrained post relies on the mechanical function of the post to provide stability which may deform or wear in-vivo leading to recurrent instability if used for a completely deficient collateral ligament. The hinge, which provides more rigid constraint, is indicated for collateral ligament deficiency. However, the additional constraint also results in greater bone-implant interface stresses, which may be mitigated by use of stem fixation to minimise risk of loosening


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_4 | Pages 105 - 105
1 Apr 2019
Kreuzer S Malanka S Pourmoghaddam A Dettmer M
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Background. Recent studies indicate the benefits of total hip arthroplasty (THA) by using femoral neck-preserving short-stem implants (March et al 1999). These benefits rely on the preservation of native hip structure and improved physiological loading. However, further investigation is needed to compare the outcome of these implants versus the conventional neck-sacrificing stems particularly assessed by patient-reported outcomes (PROs). In this study, we have investigated the differences in PROs between a neck-sacrificing stem design and neck-preserving short stem design (MiniHip, Corin Inc.). We hypothesized higher PROs outcome in patients who received treatment by using neck-preserving implants. Methods. In this study, we retrospectively analyzed the pre and post-operative PROs of patients receiving THA treatment by using neck-sacrificing implant (n=90, age 57±7.9 years) and a matched (BMI, age) cohort group of neck-preserving patients (n=105, age 55.16±9.88 years). Hip disability and Osteoarthritis Outcome Scores (HOOS) were using with the follow-up of similar follow up of 412.76 ± 206.98 days (neck sacrificing implant) and 454.63 ± 226.99 days (Neck-Preserving). Multivariate analysis of variance and Mann-Whitney tests were conducted for statistical analyses. Holm-Bonferroni adjusted for multiple comparisons was used with initial significance level of 0.05. Results. Both implants resulted in significant improvement of HOOS Subscores (p<0.001). There was a significant effect of time- surgery interaction (p=0.02). Follow-up HOOS subscores analysis indicated that patients who were treated with neck- preserving stems reported significantly higher Symptoms (p<0.001), Pain (p<0.001), ADL (p=0.011), Sports and Recreation (p=0.011), & QOL (p=0.007) subscores. Conclusion. This study aimed to investigate the short term to medium term outcome of neck-preserving implants. The superior outcome of neck-preserving femoral stems could be a result of more natural physiological loading in femoral cavity and higher retention of bone tissue in femoral neck area. However, further studies are needed to investigate the longer-term outcome of these implants


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_15 | Pages 69 - 69
1 Aug 2017
Rosenberg A
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THA: Approaches and Recovery; THA: Instability and Spinal Deformity; Revision for THA Instability: Dual Mobility Cups; Removal of Infected THA: Risk Factors for Complications; Tribocorrosion: Incidence in the Symptomatic THA; THA: Outcomes and Education Levels; THA: Satisfaction levels and Residual Symptoms; THA: Expectations and LOS; TKA: Kneeling and Recreation Expectations; TKA: Alignment and Long Term Survival; Patello-Femoral Arthroplasty vs TKA; Unicompartmental Knee Arthroplasty and Age; Wound Treatments and Sepsis in TJA; TKA: Managing Sepsis With I & D; Chronic Salvage in TKA: When is Enough Enough?; Revision TKA: Single Component Revision


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_5 | Pages 120 - 120
1 Apr 2019
Koenig JA Neuhauser-Daley K Shalhoub S Plaskos C
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Introduction. Robotic systems have been used in TKA to add precision, although few studies have evaluated clinical outcomes. We report on early clinical results evaluating patient reported outcomes (PROs) on a series of robotic-assisted TKA (RAS-TKA) patients, and compare scores to those reported in the literature. Methods. We prospectively consented and enrolled 106 patients undergoing RAS-TKA by a single surgeon performing a measured-resection femur-first technique using a miniature bone-mounted robotic system. Patients completed a KOOS, New Knee Society Score (2011 KSS) and a Veterans RAND-12 (VR-12) pre-operatively and at 3, 6 and 12 months (M) post- operatively. At the time of publication 104, 101, and 78 patients had completed 3M, 6M, and 12M PROs, respectively. Changes in the five KOOS subscales (Pain, Symptoms, Activities of Daily Living (ADL), Sport and recreation function (Sport/Rec) and Knee-related Quality of Life (QOL)) were compared to available literature data from FORCE – TJR, a large, prospective, national cohort of TJR patients enrolled from diverse high-volume centers and community orthopaedic practices in the U.S, as well as to individual studies reporting on conventional (CON-TKA) and computer-assisted (CAS- TKA) at 3M, and on conventional TKA at 6M. The 2011 KSS is a validated method for quantifying patient's expectations and satisfaction with their TKA procedure. Improvements in the 2011 KSS were compared with literature data at 6M post-operatively. Results. RAS-TKA PRO's significantly improved at 3, 6, and 12M from pre-operative baseline values. When compared to the FORCE registry cohort data, the improvement in KOOS subscales were generally higher for RAS for pain at 6M, and for pain, ADL, and QOL at 1Y when compared with FORCE 2Y data. Higher improvements were also seen at 3M, except for Sports/Rec, and at 6M for symptoms and QOL when compared with smaller cohort studies. Improvements in 2011 KSS patient satisfaction and functional scores at 6M were 11 and 10 points greater than those reported for conventional TKA. A mean of 31 pts for the Patient Satisfaction score indicates that on average patients were ‘Satisfied’ with their knee function and pain level. Mean rates of dissatisfaction with knee pain level and function were 9.2%, 3.8% and 3.1% at 3, 6, and 12M postoperatively, respectively. A mean of 10pts for the Expectation score post-operatively indicates that on average patients felt their expectations for pain relief, ADL, and leisure/sports/rec activities were between “Just Right” or “Too Low”. Discussion. Early results of RAS-TKA demonstrated significant improvements in pain, function, and QOL from baseline pre-operative values. PROs for robotic TKA also compared favorably with results reported in the literature; however, additional randomized control studies are required to provide more meaningful comparisons with conventional techniques and with other advanced technologies


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_4 | Pages 53 - 53
1 Apr 2019
Van Onsem S Verstraete M Verrewaere D Van Der Straeten C Victor J
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Background. Under- or oversizing of either component of a total knee implant can lead to early component loosening, instability, soft tissue irritation or overstuffing of joint gaps. All of these complications may cause postoperative persistent pain or stiffness. While survival of primary TKA's is excellent, recent studies show that patient satisfaction is worse. Up to 20% of the patients are not satisfied with the outcome as and residual pain is still a frequent occurrence. The goal of this study was therefore to evaluate if the sizing of the femoral component, as measured on a 3D-reconstructed projection, is related to patient reported outcome measures. From our prospectively collected TKA outcome database, all patients with a preoperative CT and a postoperative X-ray of their operated knee were included in this study. Of these 43 patients, 26 (60,5%) were women and 17 (39,5%) were men. The mean age (+/−SD) was 74,6 +/− 9 years. Methods. CT scans were acquired. All patients underwent TKA surgery in a single institution by one surgical team using the same bi- cruciate substituting total knee (Journey II BCS, Smith&Nephew, Memphis, USA). Using a recently released X-ray module in Mimics (Materialise NV, Leuven, Belgium), this module allows to align the post-operative bi-planar x-rays with the 3D- reconstructed pre-operative distal femur and to determine the 3D position of the bone and implant models using the CAD- file of the implant. This new technique was validated at our department and was found to have a sub-degree, sub-millimeter accuracy. Eleven zones of interest were defined. On the medial and the lateral condyle, the extension, mid-flexion and deep flexion facet were determined. Corresponding trochlear zones were defined and two zones were defined to evaluate the mediolateral width. In order to compare different sizes, elastic deforming mesh matching algorithms were implemented to transfer the selected surfaces from one implant to another. The orthogonal distances from the implant to the nearest bone were calculated. Positive values represent a protruding (oversized) femoral component, negative values an undersized femoral component. The figure shows the marked zones on the femoral implant. The KOOS subscores and KSS Satisfaction subscore were evaluated. Results. Two-step cluster analysis based on the clinically relevant zones on both medial (zone 12, 14 and 17) and lateral (zone 2, 5 and 9) femoral condyle of the implant, led to the formation of two clusters. Cluster 1 contained 23 patients with, in general, an undersized femoral component (negative values) whilst cluster 2 contained 20 patients with in general an oversized femoral component (positive values). (see graph) No significant differences were found between both clusters regarding demographics. Regarding PROM data, a significant difference was found for KOOS Symptoms (p=0.037) and a KOOS Pain (p=0.05). Other PROMs are not significantly different between both clusters. Conclusion. Our data shows that undersizing the femoral component results in less postoperative pain and symptoms. The clinical consequence of this study is that in case of in between femoral component sizes, the smallest size should be chosen to diminish the occurrence of postoperative pain and symptoms


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_8 | Pages 52 - 52
1 May 2019
Jacobs J
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Total Knee Arthroplasty (TKA) necessitates disruption of well-vascularised tissue during exposure and soft tissue release as well as from the cutting of bone, and thus bleeding into the joint space routinely occurs to some degree following TKA. Defining a complication from bleeding is not necessarily straightforward, but includes 3 different conditions: hemarthrosis, hematoma, and bloody wound drainage. All of these conditions can be seen in the normal postoperative setting, and when mild, may be simply observed. However, persistent swelling resulting in clinical symptoms should be appropriately treated. A hemarthrosis is defined as blood being contained in the knee capsule. Although some bleeding is expected, “excessive” hemarthrosis results in increased pain limiting or difficulty regaining motion. If high levels of fluid pressure are present, rupture of the arthrotomy may occur. A hematoma occurs when intra-articular blood escapes the arthrotomy and drains into the overlying soft tissues. This may occur following performance of a large lateral release or an insufficient arthrotomy closure or simply secondary to a large hemarthrosis under tension. Symptoms include ecchymosis, soft tissue swelling, and potential skin complications. Increased pain and limited range of motion frequently accompany these symptoms. Wound drainage may present as a knee that continues to have bloody or serous drainage that continues long after the first or second dressing change. It is this continued wound drainage that is most worrisome, with increased wound infection rates when prolonged drainage is allowed to persist. While excessive bleeding during the early postoperative period is most common, isolated or recurrent hemarthrosis may occur long after recovery from surgery. The incidence of postoperative hemarthrosis is not well studied, but the need for surgical treatment is uncommon. Recurrent hemarthrosis is also relatively rare after TKA and has been reported at rates between 0.3% and 1.6%. The etiology of this complication can be systemic or local, and initial workup should include coagulation studies to rule out any underlying systemic coagulopathy. Conservative therapy including rest, cooling, and elevation is the preferred treatment for mild cases. If conservative treatment is not successful, or the acute hemarthrosis is clinically tense, interfering with recovery, or threatening wound healing, drainage may be the preferable option. This can be done by opening the arthrotomy in the operating room or through large bore arthroscopy cannulae. Careful attention to debridement of clotted blood must be followed by a meticulous search for potential sources of bleeding which should be managed appropriately. Recurrent hemarthrosis may occur at any time but is not commonly diagnosed until the patient has left the early recovery period. Repeated bleeding episodes may lead to an inflammatory cascade that propagates bleeding events more readily. If coagulation studies are normal, the most common source is the impingement of proliferative synovium or other retained soft tissue between the articulating components of the knee prosthesis. Other causes may be multifactorial and synergistic but are not well understood, making diagnosis and treatment more difficult. If symptoms persist, classical treatment has consisted of open or arthroscopic synovectomy. Over the past decade angiography and angiographic embolization of the source of bleeding has been successful. In a recent meta-analysis including 99 patients, technical success rates of 99% were noted, though 2 cases became infected and 10 cases suffered recurrent bleeding episodes. Radio-active synovectomy has also been successful


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_10 | Pages 103 - 103
1 Jun 2018
Rosenberg A
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Total Knee Arthroplasty (TKA) necessitates disruption of well vascularised tissue during exposure and soft tissue release as well as from the cutting of bone, and thus bleeding into the joint space routinely occurs to some degree following TKA. Defining a complication from bleeding is not necessarily straightforward, but includes 3 different conditions: hemarthrosis, hematoma, and bloody wound drainage. All of these conditions can be seen in the normal post-operative setting, and when mild may be simply observed. However, persistent swelling resulting in clinical symptoms should be appropriately treated. A hemarthrosis is defined as blood being contained in the knee capsule. Although some bleeding is expected, “excessive” hemarthrosis results in increased pain limiting or difficulty regaining motion. If high levels of fluid pressure are present, rupture of the arthrotomy may occur. A hematoma occurs when intra-articular blood escapes the arthrotomy and drains into the overlying soft tissues. This may occur following performance of a large lateral release or an insufficient arthrotomy closure or simply secondary to a large hemarthrosis under tension. Symptoms include ecchymosis, soft tissue swelling, and potential skin complications. Increased pain and limited range of motion frequently accompany these symptoms. Wound drainage may present as a knee that continues to have bloody or serous drainage that continues long after the first or second dressing change. It is this continued wound drainage that is most worrisome with increased wound infection rates when prolonged drainage is allowed to persist. The incidence of post-operative hemarthrosis as a clinical problem is not well studied, but the need for surgical treatment is uncommon. Recurrent hemarthrosis is also relatively rare after total knee arthroplasty and has been reported at rates between 0.3% and 1.6%. The etiology of this complication can be systemic or local, and initial work-up should include coagulation studies to rule out any underling systemic coagulopathy. Conservative therapy including rest, cooling, and elevation is the preferred treatment for mild cases. If conservative treatment is not successful, or the acute hemarthrosis is clinically tense, interfering with recovery, or threatening wound healing, drainage may be the preferable option. This can be done by opening the arthrotomy in the operating room or through a large bore arthroscopy cannulae. Careful attention to debridement of clotted blood must be followed by a meticulous search for potential sources of bleeding which should be managed appropriately. Recurrent hemarthrosis may occur at any time after surgery. Repeated bleeding episodes may lead to an inflammatory cascade that propagates bleeding events more readily. If coagulation studies are normal, the most common source is the impingement of proliferative synovium or other retained soft tissue between the articulating components of the knee prosthesis. Other causes include damage to the geniculate or popliteal vessels with pseudo aneurysm formation. Mild to moderate clinical knee instability may be associated with bloody synovial effusions but limited clinical complaint specific to instability. Other causes may be multifactorial and synergistic but are not well understood, making diagnosis and treatment more difficult. If symptoms persist, and the resulting disability is sufficient, classical treatment has consisted of open or arthroscopic synovectomy. Over the past decade angiography and angiographic embolization of the source of bleeding has been shown to be successful. Radio-active synovectomy has also been successful


A prospective case control study analysed clinical and radiographic results in patients operated on with the periosteum autologous chondrocyte implantation (ACI) due to cartilage lesions on the femoral condyles over 10 years ago. 31 out of the 45 patients (3 failures, 9 non-responders, 2 others) were available for a continuous clinical (Lyshom/Tegner, IKDC, KOOS) and radiographic (Kellgren-Lawrence) follow-up at 0, 2, 5, and 10 years after the ACI procedure. The patients were sub-grouped into focal cartilage lesions (FL) – 10, osteochondritis dissecans (OCD) – 12, and cartilage lesions with simultaneous ACL reconstruction (ACL) – 9 subgroups. Lysholm, Tegner, and IKCD subjective scores revealed stable results over the period from 2 to 10 years with a significant improvement toward the pre-operative levels, but the patients had not reached their pre-injury Tegner levels. KOOS profile at 10 years was: Pain 78.6, Symptoms 78.1, Activities of daily living 82.5, Sports 56.9, and Quality of life 55.1. A 10-year IKDC knee examination classified operated knees as: 14 normal, 10 nearly normal, 5 abnormal and 2 severely abnormal. Kellgren-Lawrence scores of 2 and above were found in 10 patients (FL 5, OCD 0, and ACL 5). Seven patients in the group required an arthroscopic re-intervention (3 ACI related, 4 ACI unrelated). ACI provided safe and stable performance of operated knees over ten years. High incidence of knee osteoarthritis in FL and ACL subgroups, and low incidence in OCD patients indicate that best long performance is expected in localised low-impact cartilage lesions of young patients


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_22 | Pages 73 - 73
1 Dec 2016
Lonner J
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Introduction. Epidemiologic studies indicate that isolated patellofemoral (PF) arthritis affects nearly 10% of the population over 40 years of age, with a predilection for females. A small percentage of patients with PF arthritis may require surgical intervention. Surgical options include non-arthroplasty procedures (arthroscopic debridement, tibial tubercle unloading procedures, cartilage restoration, and patellectomy), and patellofemoral or total knee arthroplasty (PFA or TKA). Historically, non-arthroplasty surgical treatment has provided inconsistent results, with short-term success rates of 60–70%, especially in patients with advanced arthritis. Although TKA provides reproducible results in patients with isolated PF arthritis, it may be undesirable for those interested in a more conservative, kinematic-preserving approach, particularly in younger patients, who may account for nearly 50% of patients undergoing surgery for PF arthritis. Due to these limitations, patellofemoral arthroplasty (PFA) has become utilised more frequently over the past two decades. Indications for PFA. The ideal candidate for PFA has isolated, non-inflammatory PF arthritis resulting in “anterior” pain and functional limitations. Pain should be retro- and/or peri-patellar and exacerbated by descending stairs/hills, sitting with the knee flexed, kneeling and standing from a seated position. There should be less pain when walking on level ground. Symptoms should be reproducible during physical examination with squatting and patellar inhibition testing. An abnormal Q-angle or J-sign indicate significant maltracking and/or dysplasia, particularly with a previous history of patellar dislocations. The presence of these findings may necessitate concomitant realignment surgery with PFA. Often, patients with PF arthritis will have significant quadriceps weakness, which should be treated with preoperative physical therapy to prevent prolonged postoperative pain and functional limitations. Tibiofemoral joint pain suggests additional pathology, which may not be amenable to PFA alone. Conclusion. PFA is effective for the treatment of arthritis localised to the PF compartment. Outcomes can be optimised with proper patient selection, meticulous surgical technique, and selection of an onlay-style implant that can be positioned perpendicular to the AP axis of the femur. Minimizing the risk of patellar instability by using onlay-design PFAs has enhanced mid- and long-term results, and leaves progressive tibiofemoral arthritis as the primary failure mechanism beyond 10–15 years


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_1 | Pages 135 - 135
1 Jan 2016
Pourmoghaddam A Kreuzer S Freedhand A
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Introduction. Cementless stems have been used in treatment of patients with osteoarthritis however, the new design concept of neck preserving stems also known as short femoral stems have been utilized to decrease the potentially adverse symptoms of the standard stems such as stress shielding and thigh pain. In this ongoing study we aim to demonstrate the clinical and radiographic outcome of direct anterior approach of total hip arthroplasty (THA) by using short stem prosthesis. Methods. In this study, 390 total cases of THA in 345 patients who underwent an anterior approach of THA by using a short-stem prosthesis (Minihip, Corin) between 2009 and 2013 were reviewed. This group included 282 male and 62 female patients. Table 1 summarizes the demographic information of the patients. In 48 cases avascular necrosis (AVN) was the diagnosis and 339 cases was reported to be due to osteoarthritis. Twenty eight patients were assessed to have American Society of Anesthesiologist (ASA) physical functional score of class I, 258 patients had class II, 103 had class III, and 1 had class IV. Table 2 shows the Charnley classification of the patients. In the current study we evaluated the outcomes of the surgery by utilizing Hip Disability and Osteoarthritis Outcome Score (HOOS) subscales (Pain, Symptoms, Function in daily living (ADL), Function in sport and recreation (Sport/Rec) and Quality of life (QOL)). Results. All HOOS subscores were significantly increased postoperatively (F (5,97) = 1679, p < 0.001). The outcome are summarized in Table 4 and Figure 1. No failure of the implant has yet been reported however in 9 cases (2%) calcar fracture occurred during the surgery that was successfully treated with cerclage wires. Conclusion and Discussion. This study continues to support the excellent clinical outcomes of this short-stem prosthesis when is used for primary total hip arthroplasty. This short stem implant is an excellent choice particularly for younger individuals by preserving femoral neck bone that may provide easier revision procedures in the future


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_2 | Pages 125 - 125
1 Jan 2016
Pourmoghaddam A Kreuzer S Freedhand A
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Introduction. The concept of neck preserving stems, known as short femoral stems or metaphyseal stems has been utilized to improve the outcomes of standard cementless stems. The preservation of the proximal femoral bone stock results in decreasing the potential stress shielding and thigh pain. Additionally, these stems may be used in less invasive procedures and provide the option for easier revision procedures if implant failure occurs. In this study we aim to demonstrate the clinical outcome of direct anterior approach of total hip arthroplasty (THA) with short stem prosthesis. Methods. In this study, 390 total cases of THA in 345 patients who underwent an anterior approach of THA by using a new type of short-stem prosthesis (Minihip, Corin) between 2009 and 2013 were reviewed. There were 282 male and 62 female patients and Table 1 summarizes the demographics. In 48 cases avascular necrosis (AVN) was the diagnosis and 339 cases were reported to be due to osteoarthritis. Twenty eight patients were assessed to have American Society of Anesthesiologist (ASA) physical functional score of class I, 258 patients had class II, 103 had class III, and 1 had class IV. Table 2 shows the Charnley classification of the patients. In the current study we evaluated the outcomes of the surgery by utilizing Hip Disability and Osteoarthritis Outcome Score (HOOS) subscales (Pain, Symptoms, Function in daily living (ADL), Function in sport and recreation (Sport) and hip related Quality of life (QOL)). Results. All HOOS subscores were significantly increased from preoperative assessments (F (5,97) = 1679, p < 0.001). The outcome are summarized in Table 4 and Figure 1. No failure of the implant has yet been reported however in 9 cases (2%) calcar fracture occurred during the surgery that were successfully treated with cerclage wires. While no implant loosening was observed, there were four cases (1%) with asymptomatic subsidence (≥ 2mm). Conclusion and Discussion. This study continues to support the excellent clinical outcomes of this short-stem prosthesis when is used for primary total hip arthroplasty. Based on the current findings, we expect that this short stem implant is an excellent choice particularly for younger individuals