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The Bone & Joint Journal
Vol. 103-B, Issue 7 Supple B | Pages 9 - 16
1 Jul 2021
Hadden WJ Ibrahim M Taha M Ure K Liu Y Paish ADM Holdsworth DW Abdelbary H

Aims. The aims of this study were to develop an in vivo model of periprosthetic joint infection (PJI) in cemented hip hemiarthroplasty, and to monitor infection and biofilm formation in real-time. Methods. Sprague-Dawley rats underwent cemented hip hemiarthroplasty via the posterior approach with pre- and postoperative gait assessments. Infection with Staphylococcus aureus Xen36 was monitored with in vivo photoluminescent imaging in real-time. Pre- and postoperative gait analyses were performed and compared. Postmortem micro (m) CT was used to assess implant integration; field emission scanning electron microscopy (FE-SEM) was used to assess biofilm formation on prosthetic surfaces. Results. All animals tolerated surgery well, with preservation of gait mechanics and weightbearing in control individuals. Postoperative in vivo imaging demonstrated predictable evolution of infection with logarithmic signal decay coinciding with abscess formation. Postmortem mCT qualitative volumetric analysis showed high contact area and both cement-bone and cement-implant interdigitation. FE-SEM revealed biofilm formation on the prosthetic head. Conclusion. This study demonstrates the utility of a new, high-fidelity model of in vivo PJI using cemented hip hemiarthroplasty in rats. Inoculation with bioluminescent bacteria allows for non-invasive, real-time monitoring of infection. Cite this article: Bone Joint J 2021;103-B(7 Supple B):9–16


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_6 | Pages 77 - 77
1 Mar 2017
Wang H Foster J Franksen N Rolston L
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Background. More and more patients with end-stage knee OA are treated with total knee replacements (TKR). A modern TKR (Persona PS system, Zimmer Inc.) was designed with the hope to improve fit by providing additional sizing options on the femur and tibia. To date, there is very little information regarding the knee strength and knee mechanics during gait after the TKR. Furthermore, as a great percentage of knee OA patients have OA limited in one knee compartment and in the patellofemoral joint, a bi-compartmental knee replacement (BKR) (iDUO system, ConforMIS Inc.) was designed to treat OA at these affected areas. The BKR re-creates the individual's knee shape while correcting for any deformity. In addition, the BKR procedure results in less bone loss and retains the cruciate ligaments. To date, the influence of the BKR on knee strength and knee mechanics remains unknown. The purpose of the study was to evaluate knee strength and mechanics during level walking after the TKR and BKR surgeries. Methods. Twelve healthy control participants (age=57±6 yr.; mass=82±11 kg; height=175±11 cm), eight patients (age=63±10 yr.; mass=87±20 kg; height=166±8 cm) with ten BKR systems (post-op time = 17±9 mo.), and nine patients (age=65±9 yr.; mass=90±35 kg; Height=169±12 cm) with twelve TKR systems (post-op time = 14±5 mo.) participated in the study. In a laboratory setting, maximal isometric knee strength was evaluated. Motion capture and 3D kinematic and kinetic analyses were conducted for level walking. One way ANOVA was used to determine differences among the BKR, TKR, and the healthy control knees. Findings. The TKR knee extensor strength was 34% and 20% less than that of the control limb (p<0.05) and the BKR limb (p=0.07), respectively. The TKR limb had less knee extensor moment during walking than both the control limb (40% less) and the BKR limb (24% less) (p<0.05). The TKR knee displayed smaller internal rotation at stance than that of the control knee (60% less) and the BKR knee (50% less) (p<0.05). Both the control and BKR groups walked at a faster pace (24% and 17% faster, respectively) than the TKR group (p<0.05). No differences were found for peak knee abduction and abduction moment among the TKR, BKR, and control limbs during walking (p0.05). Interpretations. BKR patients saw their knee extensor strength returned to a normal level and were able to produce the same level of knee extensor moment of the healthy control limbs during walking. The TKR patients still experienced knee strength deficit after one year post-surgery. Both the TKR and BKR groups exhibited similar frontal plane mechanics when compared to the control limbs during walking. However, BKR patients were able to walk significantly faster than their TKR counterparts, at speeds similar to the control subjects. Patients with OA limited in the medial/lateral compartment and the patellofemoral joint may consider the BKR procedure for better knee strength recovery and functional outcomes. Acknowledgement. Funding source: ConforMIS Inc


The Bone & Joint Journal
Vol. 102-B, Issue 6 Supple A | Pages 129 - 137
1 Jun 2020
Knowlton CB Lundberg HJ Wimmer MA Jacobs JJ

Aims. A retrospective longitudinal study was conducted to compare directly volumetric wear of retrieved polyethylene inserts to predicted volumetric wear modelled from individual gait mechanics of total knee arthroplasty (TKA) patients. Methods. In total, 11 retrieved polyethylene tibial inserts were matched with gait analysis testing performed on those patients. Volumetric wear on the articular surfaces was measured using a laser coordinate measure machine and autonomous reconstruction. Knee kinematics and kinetics from individual gait trials drove computational models to calculate medial and lateral tibiofemoral contact paths and forces. Sliding distance along the contact path, normal forces and implantation time were used as inputs to Archard’s equation of wear to predict volumetric wear from gait mechanics. Measured and modelled wear were compared for each component. Results. Volumetric wear rates on eight non-delaminated components measured 15.9 mm. 3. /year (standard error (SE) ± 7.7) on the total part, 11.4 mm. 3. /year (SE ± 6.4) on the medial side and 4.4 (SE ± 2.6) mm. 3. /year on the lateral side. Volumetric wear rates modelled from patient gait mechanics predicted 16.4 mm. 3. /year (SE 2.4) on the total part, 11.7 mm. 3. /year (SE 2.1) on the medial side and 4.7 mm. 3. /year (SE 0.4) on the lateral side. Measured and modelled wear volumes correlated significantly on the total part (p = 0.017) and the medial side (p = 0.012) but not on the lateral side (p = 0.154). Conclusion. In the absence of delamination, patient-specific knee mechanics during gait directly affect wear of the tibial component in TKA. Cite this article: Bone Joint J 2020;102-B(6 Supple A):129–137


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_16 | Pages 54 - 54
1 Dec 2021
Maslivec A Ng KCG Cobb J
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Abstract. Objectives. Although hip replacement and resurfacing procedures both aim to restore mobility, improve joint function, and relieve pain, it is unclear how each differ in terms of gait mechanics and if they are affected by varying walking speeds. We compared limb symmetry and ground reaction force (GRF) profiles between bilateral total hip arthroplasty patients (THA), bilateral hip resurfacing arthroplasty patients (HRA), and healthy control participants (CON) during level-treadmill walking at different speeds. Methods. Bilateral THA and bilateral HRA patients (nTHA = 15; nHRA = 15; postoperative 12–18 months), and age-, mass-, and height-matched CON participants (nCON = 20) underwent gait analysis on an instrumented treadmill. Walking trials started at 4 km/h and increased in 0.5 km/h increments until top walking speed (TWS) was achieved. Gait symmetry index (SI = 0% for symmetry) was assessed between limbs during weight-acceptance, mid-stance and push-off phases of gait; and vertical GRFs were captured for the normalised stance phase using statistical parametric mapping (SPM; CI = 95%). Results. THA had a significantly lower TWS (6.51 ± 0.06 km/h) compared to HRA (7.09 ± 0.07 km/h, p = 0.01) and CON (7.15 km/h ± 0.06, p = 0.02). There were no SI differences between groups nor between walking speeds (SI < 5%). There were no GRF differences between groups at slower walking speeds (4.0–5.0 km/h). However, at 5.5 and 6 km/h, THA had lower GRF at the push-off phase (0.88 ± 0.09 N/BW), compared to HRA (1.06 ± 0.08 N/BW, p = 0.01) and CON (1.04 ± 0.02 N/BW, p = 0.01). Conclusions. The main finding was that HRA patients demonstrated restored gait function and similar walking profiles to CON participants at any speed. With a diverging gait profile, walking speeds over 5.5 km/h provided a functional challenge for THA patients


Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_8 | Pages 88 - 88
1 May 2014
Su E
Full Access

Flexion contractures are a common finding in an end-stage arthritic knee, occurring in up to 60% of patients undergoing total knee arthroplasty. Fixed flexion deformities may result from posterior capsular scarring, osteophyte formation, and bony impingement. It is essential to correct this deformity at the time of total knee arthroplasty, as a residual flexion contracture will result in joint overload and abnormal gait mechanics. This may translate to a slower walking velocity, shorter stride length, and pain. This presentation will discuss a systematic way of dealing with flexion contractures to ensure that the total knee arthroplasty will achieve full extension. The surgical technique for treating fixed flexion deformity about the knee includes release of the posterior cruciate ligament, posterior capsular release, adequate distal femoral bone resection, and removal of osteophytes. Postoperatively, attention must be divided between obtaining maximal flexion and full extension. Should a flexion contracture be noted upon the postoperative visit, additional measures should be taken to address it


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_6 | Pages 65 - 65
1 Mar 2017
Vasarhelyi E Petis S Lanting B Howard J
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Introduction. Total hip arthroplasty (THA) is the most effective treatment modality for severe arthritis of the hip. Patients report excellent clinical and functional outcomes following THA, including subjective improvement in gait mechanics. However, few studies in the literature have outlined the impact of THA, as well as surgical approach, on gait kinetics and kinematics. Purpose. The purpose of this study was to determine the impact of surgical approach for THA on quantitative gait analysis. Methods. Thirty patients undergoing THA for primary osteoarthritis of the hip were assigned to one of three surgical approaches (10 anterior, 10 posterior, and 10 lateral). A single surgeon performed each individual approach. Each patient received standardized implants at the time of surgery (cementless stem and acetabular component, cobalt chrome femoral head, highly cross-linked liner). Patients underwent 3D gait analysis pre-operatively, and at 6- and 12-weeks following the procedure. At each time point, temporal gait parameters, kinetics, and kinematics were compared. Statistical analysis was performed using one-way analysis of variance. Results. All three groups were similar with respect to age (p=0.27), body mass index (p=0.16), and the Charlson Comorbidity Index (p=0.66). Temporal parameters including step length, stride length, gait velocity, and percent stance and swing phase were similar between the groups at all time points. The lateral cohort had higher pelvic tilt during stance on the affected leg than the anterior cohort at 6-weeks (p=0.033). Affected leg ipsilateral trunk lean during stance was higher in the lateral group at 6-weeks (p=0.006) and 12-weeks (p=0.037) compared to the other cohorts. The anterior and posterior groups demonstrated an increased external rotation moment at 6-weeks (p=0.001) and 12-weeks (p=0.005) compared to the lateral group. Discussion. Although temporal parameters were similar across all groups, some differences in gait kinematics and kinetics exist following THA using different surgical approaches. However, the clinical relevance based on the small magnitude of the differences remains in question


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_20 | Pages 100 - 100
1 Nov 2016
Petis S Vasarhelyi E Lanting B Jones I Birmingham T Howard J
Full Access

Total hip arthroplasty (THA) is the most effective treatment modality for severe arthritis of the hip. Patients report excellent clinical and functional outcomes following THA, including subjective improvement in gait mechanics. However, few studies in the literature have outlined the impact of surgical approach on gait kinetics and kinematics. The purpose of this study was to determine the impact of surgical approach for THA on quantitative gait analysis. Thirty patients undergoing THA for primary osteoarthritis of the hip were assigned to one of three surgical approaches (10 anterior, 10 posterior, and 10 lateral). A single surgeon performed each individual approach. Each patient received standardised implants at the time of surgery (cementless stem and acetabular component, cobalt chrome femoral head, highly cross-linked liner). Patients underwent 3D gait analysis pre-operatively, and at 6- and 12-weeks following the procedure. At each time point, temporal gait parameters, kinetics, and kinematics were compared. Statistical analysis was performed using one-way analysis of variance. All three groups were similar with respect to age (p=0.27), body mass index (p=0.16), and the Charlson Comorbidity Index (p=0.66). Temporal parameters including step length, stride length, gait velocity, and percent stance and swing phase were similar between the groups at all time points. The lateral cohort had higher pelvic tilt during stance on the affected leg than the anterior cohort at 6-weeks (p=0.033). Affected leg ipsilateral trunk lean during stance was higher in the lateral group at 6-weeks (p=0.006) and 12-weeks (p=0.037) compared to the other cohorts. The anterior and posterior groups demonstrated an increased external rotation moment at 6-weeks (p=0.001) and 12-weeks (p=0.005) compared to the lateral group. Although temporal parameters were similar across all groups, some differences in gait kinematics and kinetics exist following THA using different surgical approaches. However, the clinical relevance based on the small magnitude of the differences remains in question


The Journal of Bone & Joint Surgery British Volume
Vol. 94-B, Issue 11_Supple_A | Pages 112 - 115
1 Nov 2012
Su EP

Fixed flexion deformities are common in osteoarthritic knees that are indicated for total knee arthroplasty. The lack of full extension at the knee results in a greater force of quadriceps contracture and energy expenditure. It also results in slower walking velocity and abnormal gait mechanics, overloading the contralateral limb. Residual flexion contractures after TKA have been associated with poorer functional scores and outcomes. Although some flexion contractures may resolve with time after surgery, a substantial percentage will become permanent. Therefore, it is essential to correct fixed flexion deformities at the time of TKA, and be vigilant in the post-operative course to maintain the correction. Surgical techniques to address pre-operative flexion contractures include: adequate bone resection, ligament releases, removal of posterior osteophytes, and posterior capsular releases. Post-operatively, extension can be maintained with focused physiotherapy, a specially modified continuous passive motion machine, a contralateral heel lift, and splinting


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_22 | Pages 94 - 94
1 May 2013
Su E
Full Access

Flexion contractures are a common finding in an end-stage arthritic knee, occurring in up to 60% of patients undergoing total knee arthroplasty. Fixed flexion deformities may result from posterior capsular scarring, osteophyte formation, and bony impingement. It is essential to correct this deformity at the time of total knee arthroplasty, as a residual flexion contracture will result in joint overload and abnormal gait mechanics. This may translate to a slower walking velocity, shorter stride length, and pain. This presentation will discuss a systematic way of dealing with flexion contractures to ensure that the total knee arthroplasty will achieve full extension. The surgical technique for treating fixed flexion deformity about the knee includes release of the posterior cruciate ligament, posterior capsular release, adequate distal femoral bone resection, and removal of osteophytes. Post-operatively, attention must be divided between obtaining maximal flexion and full extension. Should a flexion contracture be noted upon the post-operative visit, additional measures should be taken to address it


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_20 | Pages 1 - 1
1 Nov 2016
Outerleys J Dunbar M Richardson G Kozey C Wilson J
Full Access

Total knee arthroplasty (TKA) has been shown to improve knee joint function during gait post-operatively. However, there is considerable patient to patient variability, with most gait mechanics metrics not reaching asymptomatic levels. To understand how to target functional improvements with TKA, it is important to identify an optimal set of functional metrics that remain deficient post-TKA. The purpose of this study was to identify which combination of knee joint kinematics and kinetics during gait best discriminate pre-operative gait from postoperative gait, as well as post-operative from asymptomatic. Seventy-three patients scheduled to receive a TKA for severe knee osteoarthritis underwent 3D gait analysis 1 week before and 1 year after surgery. Sixty asymptomatic individuals also underwent analysis. Eleven discrete gait parameters were extracted from the gait kinematic and kinetic waveforms, as previously defined (Astephen et al., J Orthop Res., 2008). Stepwise linear discriminant analyses were used to determine the sets of parameters that optimally separated pre-operative from post-operative gait, and post-operative from asymptomatic gait. Cross-validation was used to quantify group classification error. Knee flexion angle range, knee adduction moment first peak, and gait velocity were included in the optimal discriminant function between the pre- and post-operative groups (P<0.05), with relatively equal standardised canonical coefficients (0.567, −0.501, 0.565 respectively), and a total classification rate of 74%. A number of metrics were included in the discriminant function to optimally separate post-operative and asymptomatic gait function, including the knee flexion angle range, peak stance knee flexion angle, minimum late stance knee extension moment, minimum mid-stance knee adduction moment, and peak knee internal rotation moment (P<0.05). The mid-stance knee adduction moment had the largest standardised canonical coefficients in the function, and 89.5% of cases were correctly classified. Separation of pre and post-operative gait patterns included only three parameters, suggesting that current standard of care TKA significantly improves only walking velocity, knee flexion angle range, and the peak value of the knee adduction moment. A number of gait metrics, which were included in the discriminant function between post-operative and asymptomatic gait, could benefit from further improvement either through rehabilitation or design. With almost 90% classification, separation of post-operative gait function from asymptomatic levels is significant. The consolidation of knee joint function during gait into single, discrete discriminant scores allows for an efficient summary representation of patient-specific (or implant-specific) improvement in gait function from TKA surgery


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_22 | Pages 42 - 42
1 May 2013
Stulberg S
Full Access

Navigation has been felt to play a role in a number of THA issues. These issues include: 1) Instability-Dislocation; 2) Leg Length discrepancy; 3) Impingement and its impact on range of motion and wear; 3) gait mechanics; and 4) less invasive surgery. Navigation requires that anatomic landmarks be accurately identified. This can be done using images obtained either pre-operatively or intra-operatively (image-based navigation) or using intra-operative techniques for registering the relevant bony anatomy (image-free). The suggested advantages of imaged-based navigation are that is potentially very accurate, makes registering bone landmarks relatively easy and provides information about relevant anatomic landmarks that are not visible during surgery. The disadvantages of image-based navigation are that the acquisition of pre-operative imaging may be inconvenient or cumbersome, the imaging may be associated with increased radiation exposure, the imaging may be associated with additional costs and the pre-operative planning carried out on the imaging may be elaborate and time consuming. The advantages of image-free navigation are that no special pre-operative planning is required, no special imaging is necessary and the intra-operative workflow is consistent with the routine performance of a THA. However, image free registration techniques may be unreliable or inaccurate and the information obtained with image-free registration techniques is limited. When surgeons proficient in the technique perform image free navigation, positioning of the acetabular component is more accurate and consistent than that achieved using manual techniques. However, this increased accuracy has not been associated with a reduction in hip dislocations and has not had a measurable impact on short-term clinical outcomes. However, navigation is an accurate measurement tool that can be used to validate other computer-based technologies (e.g. patient specific guides). Navigation is also essential to the performance of robotic hip surgery. It is in this latter capacity that navigation may prove most useful to the hip surgeon


Bone & Joint Research
Vol. 13, Issue 6 | Pages 279 - 293
7 Jun 2024
Morris JL Letson HL McEwen PC Dobson GP

Aims

Adenosine, lidocaine, and Mg2+ (ALM) therapy exerts differential immuno-inflammatory responses in males and females early after anterior cruciate ligament (ACL) reconstruction (ACLR). Our aim was to investigate sex-specific effects of ALM therapy on joint tissue repair and recovery 28 days after surgery.

Methods

Male (n = 21) and female (n = 21) adult Sprague-Dawley rats were randomly divided into ALM or Saline control treatment groups. Three days after ACL rupture, animals underwent ACLR. An ALM or saline intravenous infusion was commenced prior to skin incision, and continued for one hour. An intra-articular bolus of ALM or saline was also administered prior to skin closure. Animals were monitored to 28 days, and joint function, pain, inflammatory markers, histopathology, and tissue repair markers were assessed.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_28 | Pages 112 - 112
1 Aug 2013
Kress K Anderson C
Full Access

Acetabular component positioning is highly correlated with total hip arthroplasty (THA) outcomes. Multiple reports however indicate that less than 50% of acetabular cups are placed within surgeon-desired ranges for abduction and anteversion angles when using conventional cup positioning techniques. Issues with improper placement include instability-dislocation, impingement and impact on range of motion, polyethylene wear, leg length discrepancy, and gait mechanics. Accuracy in placement of the acetabular component is complicated by the need to estimate cup impactor angles to create desired cup position. A low cost approach to THA using Image-based Ultrasonic Guidance (IUG) (Orthosensor, Sunrise, FL) coupled to existing surgical tools is presented. IUG utilises acoustic measurement techniques for achieving optimal component positioning and leg length. A precisely machined Hip Test Fixture (HTF) has been built to simulate the anatomical pelvis, acetabular cup, and femur to validate system accuracy. The IUG was affixed to the HTF to demonstrate placement of the cup during THA. The HTF was loaded onto a 27-inch Graphic User Interface (GUI) providing three-dimensional CAD data of the HTF. Registration points included the Iliac Crest and 10 points around the acetabular cup. These points were mapped to the CAD data by the GUI. The HTF was set to 45° of abduction and 0° of version to begin testing. Abduction and version were measured over a +15° range in 1-degree increments while leg length and offset were measured over a +5mm range in 2mm increments. A high-resolution coordinate measurement machine (FaroArm EDGE) verified the accuracy and margin of error for inclination, version, leg length and offset at each increment. The HTF provided a precise means for evaluating IUG system accuracy of simulated THA in a controlled environment. Acceptable margins of error were reported on the HTF: mean error for version was 0.36° (SD 0.02°; 0.25° to 0.38°); mean error for inclination was 1.04° (SD 0.52°; 0.48° to 1.66°); mean error for leg length and offset were respectively 0.36mm (SD 0.86mm; −0.65 to 1.55mm) and 0.41mm (SD 0.28; 0.05 to 0.80mm). IUG provides a means for achieving acceptable precision and accuracy in component placement during THA as evaluated with the HTF. Further study is however necessary to correlate accuracy of IUG with clinical utility and short-term clinical outcomes


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 143 - 143
1 Mar 2008
Daniels T Duggal N Redekop S Yeung M
Full Access

Purpose: 1/ To compare patients treated with both ankle arthroplasty or ankle fusion using validated functional outcome measures and a computerized motion analysis system that measures three-dimensional kinematics and temporal data. 2/ To compare the functional outcome and gait mechanics of ankle arthroplasty and ankle arthrodesis to a healthy control group. Methods: Fifteen patients underwent seventeen ankle arthroplasties with the Scandinavian Total Ankle Replacement (STAR), twenty-three patients underwent ankle arthrodesis, and twenty-three healthy control patients were enrolled in this study. Assessment included: 1/ Ankle Osteoarthritis Scale (AOS) and general health status (SF-36). 2/ Gait data, including temporal-spatial, kinematic, and kinetic parameters using a seven-camera VICON 370 system (Oxford Metrics, UK). Comparison between groups was done using one-way ANOVA post hoc Bonferroni (p< 0.05). Results: Kinematic gait parameters for post-op arthrodesis, post-op arthroplasty and a control group are summarized in Table 1. Postoperative arthrodesis patients had significantly reduced ankle range of motion in the sagittal and frontal plane when compared to both postoperative arthroplasty patients and a control group (p< 0.05). Forefoot range of motion was also significantly reduced in the sagittal and frontal planes for arthrodesis patients when compared to the control group, however there were no significant differences between patient groups or between arthroplasty patients and controls (p< 0.05).|Functional questionnaire (AOS) data for the three groups is summarized in Table 2. There were no significant differences in patient perception of pain and disability, however AOS scores compared between arthrodesis patients and a control group were significant (p< 0.05). No difference was noted in AOS scores between ankle arthroplasty and control patients at one year post operative. Conclusions: Functional outcome analysis of treatment methods of end-stage ankle arthritis clearly shows the advantage of ankle arthroplasty over arthrodesis when comparing kinematic and outcome questionnaire data against controls. The results of this study will help determine the best surgical treatment for patients with end-stage ankle arthritis failing non-operative treatment


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 555 - 555
1 Nov 2011
Varin D Lamontagne M Beaulieu M Beaulé PE
Full Access

Purpose: It is thought that the anterior approach better restores gait mechanics after total hip arthroplasty (THA) being a pure intermuscular/internervous approach. The purpose of this study was to compare three-dimensional (3-D) kinematics and kinetics of THA patients that had an anterior (ANT) vs. a lateral (LAT) approach. It is hypothesized that the ANT group will exhibit fewer differences than the LAT group when compared to a control group (CON). Method: Fifty-four participants were divided into three groups of 18: ANT (12 women, 6 men; age: 60.9 ± 6.2 yr; BMI: 28.8 ± 4.9 kg/m2), LAT (10 women, 8 men; age: 65.2 ± 6.3 yr; BMI: 27.5 ± 5.1 kg/m2) and CON (9 women, 9 men; age: 63.9 ± 4.4 yr; BMI: 25.4 ± 3.2 kg/ m2). All THA patients had primary unilateral THA due to osteoarthritis and had no other lower-limb pathology. They were evaluated five to 17 months after surgery. 3-D kinematics and kinetics were obtained using a nine-camera motion analysis system and a force platform placed on the first step of a staircase. Each participant performed three trials of stair ascending. A series of one-way ANOVAs were used to compare peak angles, range of motion (ROM), peak resultant joint forces as well as moments and powers of the hip, knee and ankle joints in all three planes. Results: Most differences occurred during transitions between double- to single-legged stance. Both LAT and ANT groups ascended the staircase with a more abducted hip than the CON group, resulting in reduced hip abduction moment. This could be the result of the implant’s position and its potential abductor lever arm reduction. Both groups also showed reduced peak internal rotation moments. These results have previously been found in THA patients who have been operated through lateral and posterior approaches, and are thought to be caused by hip abductor muscle damage inherent to the surgical approach. However, only the LAT group had lower compression forces at the hip, knee and ankle joints compared to the CON group. This indicates that LAT group uses a strategy that reduces the loading on the operated leg, which may be due to the detachment of the anterior third of the gluteus medius. It could be speculated that the muscle sparing aspect of ANT approach allows patients to load adequately their operated leg, even if their frontal plane kinematics and kinetics are altered. Conclusion: Some studies have failed to find differences with the anterior approach. However, they have only looked at spatiotemporal gait parameters. 3-D kinematics and kinetics can provide a more detailed assessment of function and detect more subtle differences. In this study, 3-D biomechanical analysis has detected differences in THA patients operated through different surgical approaches during stair ascent. The data obtained showed similar frontal plane kinematics for both groups, but different lower-limb compression forces. This study supports the use of the anterior approach for better restoration of function after total hip arthroplasty


Bone & Joint 360
Vol. 11, Issue 3 | Pages 40 - 43
1 Jun 2022


Bone & Joint 360
Vol. 6, Issue 4 | Pages 16 - 18
1 Aug 2017


The Bone & Joint Journal
Vol. 95-B, Issue 2 | Pages 192 - 198
1 Feb 2013
Ackman J Altiok H Flanagan A Peer M Graf A Krzak J Hassani S Eastwood D Harris GF

Van Nes rotationplasty may be used for patients with congenital proximal focal femoral deficiency (PFFD). The lower limb is rotated to use the ankle and foot as a functional knee joint within a prosthesis. A small series of cases was investigated to determine the long-term outcome. At a mean of 21.5 years (11 to 45) after their rotationplasty, a total of 12 prosthetic patients completed the Short-Form (SF)-36, Faces Pain Scale-Revised, Harris hip score, Oswestry back pain score and Prosthetic Evaluation Questionnaires, as did 12 age- and gender-matched normal control participants. A physical examination and gait analysis, computerised dynamic posturography (CDP), and timed ‘Up & Go’ testing was also completed. Wilcoxon Signed rank test was used to compare each PFFD patient with a matched control participant with false discovery rate of 5%.

There were no differences between the groups in overall health and well-being on the SF-36. Significant differences were seen in gait parameters in the PFFD group. Using CDP, the PFFD group had reduced symmetry in stance, and reduced end point and maximum excursions.

Patients who had undergone Van Nes rotationplasty had a high level of function and quality of life at long-term follow-up, but presented with significant differences in gait and posture compared with the control group.

Cite this article: Bone Joint J 2013;95-B:192–8.


The Journal of Bone & Joint Surgery British Volume
Vol. 93-B, Issue 6 | Pages 769 - 776
1 Jun 2011
Hogervorst T Bouma H de Boer SF de Vos J

We examined the morphology of mammalian hips asking whether evolution can explain the morphology of impingement in human hips. We describe two stereotypical mammalian hips, coxa recta and coxa rotunda. Coxa recta is characterised by a straight or aspherical section on the femoral head or head-neck junction. It is a sturdy hip seen mostly in runners and jumpers. Coxa rotunda has a round femoral head with ample head-neck offset, and is seen mostly in climbers and swimmers.

Hominid evolution offers an explanation for the variants in hip morphology associated with impingement. The evolutionary conflict between upright gait and the birth of a large-brained fetus is expressed in the female pelvis and hip, and can explain pincer impingement in a coxa profunda. In the male hip, evolution can explain cam impingement in coxa recta as an adaptation for running.