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Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_13 | Pages 51 - 51
7 Aug 2023
Fabiano G Smith T Parsons S Ooms A Dutton S Fordham B Hing C Pinedo-Villanueva R Lamb S
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Abstract. INTRODUCTION. This study aimed to examine how physical activity and health-related quality of life (HRQoL) evolved over the first year after total knee replacement (TKR) for patients with and without post-operative chronic knee pain. METHODS. 83 adults participating in the PEP-TALK, a RCT testing the effectiveness of a behaviour change physiotherapy intervention versus usual rehabilitation post-primary TKR, were analysed. UCLA Activity Score and EQ-5D-5L values for participants with and without chronic knee pain (14 points or lower in the Oxford Knee Score Pain Subscale at six months post-TKR) were compared at six and 12 months post-TKR. We evaluated recovery trajectory those with or without chronic pain at these time points. RESULTS. Participants with chronic knee pain, UCLA Activity Score remained unchanged between baseline to six months (mean: 3.8 to 3.8), decreasing at 12 months (mean: 3.0). Those without post-operative chronic knee pain reported a improvement in physical activity from baseline to six months (mean: 4.0 vs 4.9), plateauing at 12 months (mean: 4.9). Participants with chronic knee pain reported lower baseline HRQoL, although both groups improved mean health utility over one year. Of participants who were not defined as being in chronic pain at six months, 8.5% returned to a chronic pain categorisation by 12 months. CONCLUSION. People with chronic knee pain post-TKR report poorer physical activity and HRQoL scores post-operatively. Monitoring outcomes longer than six months may be indicated as those without chronic knee pain initially post-TKR remain at risk of reverting to chronic knee pain 12 months post-TKR


The Bone & Joint Journal
Vol. 102-B, Issue 1 | Pages 125 - 131
1 Jan 2020
Clement ND Weir DJ Holland J Deehan DJ

Aims. The primary aim of this study was to assess whether pain in the contralateral knee had a clinically significant influence on the outcome of total knee arthroplasty (TKA) according to the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score. Secondary aims were to: describe the prevalence of contralateral knee pain; identify if it clinically improves after TKA; and assess whether contralateral knee pain independently influences patient satisfaction with their TKA. Methods. A retrospective cohort of 3,178 primary TKA patients were identified from an arthroplasty database. Patient characteristics, comorbidities, and WOMAC scores were collected preoperatively and one year postoperatively for the index knee. In addition, WOMAC pain scores were also collected for the contralateral knee. Overall patient satisfaction was assessed at one year. Preoperative contralateral knee pain was defined according to the WOMAC score: minimal (> 78 points), mild (59 to 78), moderate (44 to 58), and severe (< 44). Multivariate regression analysis was used to adjust for confounding. Results. According to severity there were 1,425 patients (44.8%) with minimal, 710 (22.3%) with mild, 518 (16.3%) with moderate, and 525 (16.5%) with severe pain in the contralateral knee. Patients in the severe group had a greater clinically significant improvement in their functional WOMAC score (9.8 points; p < 0.001). Only patients in the moderate (22.9 points) and severe (37.8 points) groups had a clinically significant improvement in their contralateral knee pain (p < 0.001), but they were significantly less likely to be satisfied with their TKA (moderate: odds ratio (OR) 0.64, 95% confidence interval (CI) 0.4 to 0.92, p = 0.022; severe: OR 0.57, 95% CI 0.39 to 0.82, p = 0.002). Conclusion. Contralateral knee pain did not impair improvement in the WOMAC score after TKA, and patients with the most severe contralateral knee pain had a clinically significantly greater improvement in their functional outcome. More than half the patients presenting for TKA had mild-to-severe contralateral knee pain, most of whom had a clinically meaningful improvement but were significantly less likely to be satisfied with their TKA. Cite this article: Bone Joint J. 2020;102-B(1):125–131


Bone & Joint Research
Vol. 13, Issue 6 | Pages 261 - 271
1 Jun 2024
Udomsinprasert W Mookkhan N Tabtimnark T Aramruang T Ungsudechachai T Saengsiwaritt W Jittikoon J Chaikledkaew U Honsawek S

Aims. This study aimed to determine the expression and clinical significance of a cartilage protein, cartilage oligomeric matrix protein (COMP), in knee osteoarthritis (OA) patients. Methods. A total of 270 knee OA patients and 93 healthy controls were recruited. COMP messenger RNA (mRNA) and protein levels in serum, synovial fluid, synovial tissue, and fibroblast-like synoviocytes (FLSs) of knee OA patients were determined using enzyme-linked immunosorbent assay, real-time polymerase chain reaction, and immunohistochemistry. Results. COMP protein levels were significantly elevated in serum and synovial fluid of knee OA patients, especially those in the advanced stages of the disease. Serum COMP was significantly correlated with radiological severity as well as measures of body composition, physical performance, knee pain, and disability. Receiver operating characteristic curve analysis unveiled a diagnostic value of serum COMP as a biomarker of knee OA (41.64 ng/ml, area under the curve (AUC) = 1.00), with a sensitivity of 99.6% and a specificity of 100.0%. Further analysis uncovered that COMP mRNA expression was markedly upregulated in the inflamed synovium of knee OA, consistent with immunohistochemical staining revealing localization of COMP protein in the lining and sub-lining layers of knee OA inflamed synovium. Most notably, relative COMP mRNA expression in knee OA synovium was positively associated with its protein levels in serum and synovial fluid of knee OA patients. In human knee OA FLSs activated with tumour necrosis factor-alpha, COMP mRNA expression was considerably up-regulated in a time-dependent manner. Conclusion. All results indicate that COMP might serve as a supportive diagnostic marker for knee OA in conjunction with the standard diagnostic methods. Cite this article: Bone Joint Res 2024;13(6):261–271


Bone & Joint Open
Vol. 4, Issue 3 | Pages 158 - 167
10 Mar 2023
Landers S Hely R Hely A Harrison B Page RS Maister N Gwini SM Gill SD

Aims. This study investigated the effects of transcatheter arterial embolization (TAE) on pain, function, and quality of life in people with early-stage symptomatic knee osteoarthritis (OA) compared to a sham procedure. Methods. A total of 59 participants with symptomatic Kellgren-Lawrence grade 2 knee OA were randomly allocated to TAE or a sham procedure. The intervention group underwent TAE of one or more genicular arteries. The control group received a blinded sham procedure. The primary outcome was knee pain at 12 months according to the Knee injury and Osteoarthritis Outcome Score (KOOS) pain scale. Secondary outcomes included self-reported function and quality of life (KOOS, EuroQol five-dimension five-level questionnaire (EQ-5D-5L)), self-reported Global Change, six-minute walk test, 30-second chair stand test, and adverse events. Subgroup analyses compared participants who received complete embolization of all genicular arteries (as distinct from embolization of some arteries) (n = 17) with the control group (n = 29) for KOOS and Global Change scores at 12 months. Continuous variables were analyzed with quantile regression, adjusting for baseline scores. Dichotomized variables were analyzed with chi-squared tests. Results. Overall, 58 participants provided questionnaire data at 12 months. No significant differences were found for the primary and secondary outcomes, with both groups improving following the procedure. At 12 months, KOOS pain scores improved by 41.3% and 29.4% in the intervention and control groups, respectively. No adverse events occurred. Subgroup analysis indicated that the complete embolization group had significantly better KOOS Sports and Recreation, KOOS Quality of Life, and Global Change scores than the control group; 76.5% of participants who received complete embolization reporting being moderately or much better compared to 37.9% of the control group. Conclusion. TAE might produce benefits above placebo, but only when complete embolization of all genicular arteries is performed. Further comparative studies are required before definitive conclusions regarding the effectiveness of TAE can be made. Level of evidence: I. Cite this article: Bone Jt Open 2023;4(3):158–167


The Bone & Joint Journal
Vol. 104-B, Issue 9 | Pages 1089 - 1094
1 Sep 2022
Banskota B Yadav P Rajbhandari A Aryal R Banskota AK

Aims. To examine the long-term outcome of arthrodesis of the hip undertaken in a paediatric population in treating painful arthritis of the hip. In our patient population, most of whom live rurally in hilly terrain and have limited healthcare access and resources, hip arthrodesis has been an important surgical option for the monoarticular painful hip in a child. Methods. A follow-up investigation was undertaken on a cohort of 28 children previously reported at a mean of 4.8 years. The present study looked at 26 patients who had an arthrodesis of the hip as a child at a mean follow-up of 20 years (15 to 29). Results. The mean Harris Hip Score (HHS) increased from 39.60 (SD 11.06) preoperatively to 81.02 (SD 8.86; p = 0.041) at final review. At latest follow-up, the HHS was found to be excellent in four patients (15%), good in 11 (42%), and fair in 11 (42%). A total of 16 patients (62%) reported mild low back pain, five (19%) had moderate pain, and five (19%) patients had no back pain. Mild ipsilateral knee pain was reported by 19 (73%), moderate pain by one (4%), and no pain by six (23%) patients. Mild contralateral hip pain was reported by ten patients (38%), and no pain by 16 (62%). The 36-Item Short Form Health Survey scores were very good in four patients (15%), good in 18 (70%), and poor in four (15%), with a mean score of 70.92 (SD 12.65). Of 13 female patients who had given birth, 12 did so with uncomplicated vaginal delivery. All patients had to modify their posture for toileting, putting on lower body clothes, foot care, and putting on shoes. Conclusion. Our results show that with hip arthrodesis, most patients have relatively good function at long-term follow-up, although some pain is experienced in adjacent joints, and modification in some activities of daily living is common. Cite this article: Bone Joint J 2022;104-B(9):1089–1094


The Bone & Joint Journal
Vol. 99-B, Issue 5 | Pages 632 - 639
1 May 2017
Hamilton TW Pandit HG Maurer DG Ostlere SJ Jenkins C Mellon SJ Dodd CAF Murray DW

Aims. It is not clear whether anterior knee pain and osteoarthritis (OA) of the patellofemoral joint (PFJ) are contraindications to medial unicompartmental knee arthroplasty (UKA). Our aim was to investigate the long-term outcome of a consecutive series of patients, some of whom had anterior knee pain and PFJ OA managed with UKA. Patients and Methods. We assessed the ten-year functional outcomes and 15-year implant survival of 805 knees (677 patients) following medial mobile-bearing UKA. The intra-operative status of the PFJ was documented and, with the exception of bone loss with grooving to the lateral side, neither the clinical or radiological state of the PFJ nor the presence of anterior knee pain were considered a contraindication. The impact of radiographic findings and anterior knee pain was studied in a subgroup of 100 knees (91 patients). Results. There was no relationship between functional outcomes, at a mean of ten years, or 15-year implant survival, and pre-operative anterior knee pain, or the presence or degree of cartilage loss documented intra-operatively at the medial patella or trochlea, or radiographic evidence of OA in the medial side of the PFJ. In 6% of cases there was full thickness cartilage loss on the lateral side of the patella. In these cases, the overall ten-year function and 15-year survival was similar to those without cartilage loss; however they had slightly more difficulty with descending stairs. Radiographic signs of OA seen in the lateral part of the PFJ were not associated with a definite compromise in functional outcome or implant survival. Conclusion. Severe damage to the lateral side of the PFJ with bone loss and grooving remains a contraindication to mobile-bearing UKA. Less severe damage to the lateral side of the PFJ and damage to the medial side, however severe, does not compromise the overall function or survival, so should not be considered to be a contraindication. However, if a patient does have full thickness cartilage loss on the lateral side of the PFJ they may have a slight compromise in their ability to descend stairs. Pre-operative anterior knee pain also does not compromise the functional outcome or survival and should not be considered to be a contraindication. Cite this article: Bone Joint J 2017;99-B:632–9


The Bone & Joint Journal
Vol. 101-B, Issue 9 | Pages 1138 - 1143
1 Sep 2019
MacDonald DRW Caba-Doussoux P Carnegie CA Escriba I Forward DP Graf M Johnstone AJ

Aims. The aim of this study was to compare the incidence of anterior knee pain after antegrade tibial nailing using suprapatellar and infrapatellar surgical approaches. Patients and Methods. A total of 95 patients with a tibial fracture requiring an intramedullary nail were randomized to treatment using a supra- or infrapatellar approach. Anterior knee pain was assessed at four and six months, and one year postoperatively, using the Aberdeen Weightbearing Test – Knee (AWT-K) score and a visual analogue scale (VAS) score for pain. The AWT-K is an objective patient-reported outcome measure that uses weight transmitted through the knee when kneeling as a surrogate for anterior knee pain. Results. A total of 53 patients were randomized to a suprapatellar approach and 42 to an infrapatellar approach. AWT-K results showed a greater mean proportion of weight transmitted through the injured leg compared with the uninjured leg when kneeling in the suprapatellar group compared with the infrapatellar group at all timepoints at all follow-up visits. This reached significance at four months for all timepoints except 30 seconds. It also reached significance at six months at 0 seconds, and for one year at 60 seconds. Conclusion. The suprapatellar surgical approach for antegrade tibial nailing is associated with less anterior knee pain postoperatively compared with the infrapatellar approach. Cite this article: Bone Joint J 2019;101-B:1138–1143


The Bone & Joint Journal
Vol. 105-B, Issue 9 | Pages 961 - 970
1 Sep 2023
Clement ND Galloway S Baron YJ Smith K Weir DJ Deehan DJ

Aims. The primary aim was to assess whether robotic total knee arthroplasty (rTKA) had a greater early knee-specific outcome when compared to manual TKA (mTKA). Secondary aims were to assess whether rTKA was associated with improved expectation fulfilment, health-related quality of life (HRQoL), and patient satisfaction when compared to mTKA. Methods. A randomized controlled trial was undertaken, and patients were randomized to either mTKA or rTKA. The primary objective was functional improvement at six months. Overall, 100 patients were randomized, 50 to each group, of whom 46 rTKA and 41 mTKA patients were available for review at six months following surgery. There were no differences between the two groups. Results. There was no difference between rTKA and mTKA groups at six months according to the Western Ontario and McMaster Universities osteoarthritis index (WOMAC) functional score (mean difference (MD) 3.8 (95% confidence interval (CI) -5.6 to 13.1); p = 0.425). There was a greater improvement in the WOMAC pain score at two months (MD 9.5 (95% CI 0.6 to 18.3); p = 0.037) in the rTKA group, although by six months no significant difference was observed (MD 6.7 (95% CI -3.6 to 17.1); p = 0.198). The rTKA group were more likely to achieve a minimal important change in their WOMAC pain score when compared to the mTKA group at two months (n = 36 (78.3%) vs n = 24 (58.5%); p = 0.047) and at six months (n = 40 (87.0%) vs n = 29 (68.3%); p = 0.036). There was no difference in satisfaction between the rTKA group (97.8%; n = 45/46) and the mTKA group (87.8%; n = 36/41) at six months (p = 0.096). There were no differences in EuroQol five-dimension questionnaire (EQ-5D) utility gain (p ≥ 0.389) or fulfilment of patient expectation (p ≥ 0.054) between the groups. Conclusion. There were no statistically significant or clinically meaningful differences in the change in WOMAC function between mTKA and rTKA at six months. rTKA was associated with a higher likelihood of achieving a clinically important change in knee pain at two and six months, but no differences in knee-specific function, patient satisfaction, health-related quality of life, or expectation fulfilment were observed. Cite this article: Bone Joint J 2023;105-B(9):961–970


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_11 | Pages 65 - 65
1 Oct 2019
Mayman DJ Sutphen S Bawa H Carroll KM Jerabek SA Haas SB
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Introduction. Up to 15 % of patients report anterior knee pain (AKP) after a total knee arthroplasty (TKA). The correlation of radiographic patellar measurements and post-operative AKP remains controversial. The purpose of this study was to determine whether any radiographic measurements can predict anterior knee pain after TKA. Methods. We performed a retrospective analysis of data on 343 patients who underwent a primary unilateral TKA between 2009–2012 at a single institution. Post-operative radiographs were evaluated with standing anteroposterior, lateral, and merchant views. Radiographic assessment was performed to assess posterior offset, Insall Salvati ratio, Blackburne, PP angle, Patella thickness, Congruence angle, Patella tilt, and patella displacement. Clinical function was assessed by the Kujala anterior knee pain scale at a minimum of 5 years. Patients were asked if they currently had anterior knee pain post-operatively by responding “yes” or “no.” There were 264 females and 79 males; the mean age at surgery was 64.2 ± 9.7 (range, 42–92 years) years; the mean BMI 31±5.8 kg/m. 2. (range, 18.8–49 kg/m. 2. ). Results. Of the 343 patients, 46 patients (13.4%) patients suffered persistent AKP at a minimum 5 years follow-up. Radiographic measurements were performed. Although we had large variations in congruence angle, patellar tilt and patellar displacement, these variations had no correlation with anterior knee pain (p=0.885). We were not able to detect statistical significance among clinical outcome Kujala score and patient reported AKP (p=0.713) at minimum 5 year follow-up. Discussion. Persistent anterior knee pain is troubling to patients and surgeons. Clinicians often get concerned when they see variability in these radiographic findings. Our findings suggest that variations in radiographic parameters do not predict anterior knee pain following total knee replacement surgery. For figures, tables, or references, please contact authors directly


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_I | Pages 20 - 20
1 Jan 2003
Takagi H Mori Y Fujimoto A Kanai H Yamashita H Kawakami Y
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Our purpose was to evaluate the incidence of anterior knee pain after ACL reconstruction and the associated affecting factors. The study assessed 50 ACL reconstructed knees: 29 males and 21 females. The age at surgery was from 14 to 39 years old, with 23.7 years old on the average. The ACL injury was unilateral in all cases, and the normal side was defined as the control. We treated chronic ACL-deficient knees by reconstruction of the ligament through a limited arthrotomy using one-third of the patellar tendon (BTB) with the Kennedy LAD as a graft. Anterior knee pain was classified into 4 group: absent, trace-mild, moderate, and severe. We evaluated the height of the patella, knee extension strength, anterior laxity, leg rotation, Lysholm score, and loss of extension. Anterior laxity and leg rotation were measured by a three-dimensional analyzer. Ten of the fifty knees (20%) had anterior knee pain. Knee extension strength (reconstructed side/control side) was 71.1% in the cases with anterior knee pain and 84.2% in the cases without anterior knee pain. A significant difference was found between these values. Regarding leg rotation, 4 knees showed normal leg rotation (physiological screw home movement) in the cases with anterior knee pain, compared to 31 knees in the cases without anterior knee pain. There was a significant difference in the incidence of anterior knee pain between the cases with normal leg rotation and the cases without. Other factors failed to show any significant correlation. In this study, knee extension strength and leg rotation had a correlation with anterior knee pain


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 48 - 48
1 Mar 2008
Bednar D Salem J
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Retrograde nailing of femoral shaft fractures has been a routine trauma practice option for approximately five years and may be technically advantaged in many situations. Earlier review of our antegrade experience revealed that 30% of standard nails are recognized to frequently cause pain (30%) and/or heterotopic ossification at the hip; knee pain of unclear etiology was found frequently as well (13%). This review of our preliminary experience with retrograde nails found a 30% frequency of nonspecific knee pain complaints at a mean of thirty-four months. No ectopic ossification was seen and no nails had been removed. The purpose of this study was to review the experience of patients who have undergone retrograde femoral nailing with regard to possible knee pain complaints. Chart and imaging records were reviewed retrospectively. Patients were contacted and interviewed by telephone to determine late pain complaints. From January 2000 through February 2002, eighteen patients were treated for twenty-two femoral shaft fractures. The group included ten males and and eight females of mean age 54.5 years (range, nineteen to ninety years). Treatment was with Synthes retrograde femoral nails, reamed and statically locked, inserted under fluoroscopic control on a radiolucent table using a Tenet™ leg holder. At thirty-four months, all fractures had healed primarily with no appreciable malalignment, no infections and no nonunions. No intraarticular free bodies or ectopic ossification were seen. Eleven patients were asymptomatic with regard to the index injured extremity. Five had mild to moderate pain, generally localized anteriorly, without associated articular symptoms and not requiring any analgesia. Two had severe symptoms of diffuse knee pain with radiographic degenerative changes noted, but these were cases with associated complex tibial plateau fractures to account for it. Even eliminating these two patients, fully five of sixteen patients (30%) without associated periarticular trauma at the knee had mild to moderate nondisabling anterior knee pain complaints after retrograde femoral nailing. The frequency of anterior knee pain complaints after retrograde femoral nailing is significant. Previous authors have found knee pain complaints in 27–29% of cases. We found no evidence of articular derangement in our patients undergoing retrograde femoral nailing in the absence of associated periarticular trauma at the knee, we confirm a 30% frequency of nonspecific knee pain complaints persisting at almost three years after injury. Patients should be made aware that, at intermediate-term follow-up, mild to moderate knee pain may be a result of this fracture treatment


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_10 | Pages 102 - 102
1 Jun 2018
Jones R
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Total knee arthroplasty (TKA) is one of the most common orthopaedic operations performed worldwide and it is largely successful in pain relief and functional recovery. However, when pain persists post-operatively the thorough evaluation must be instituted. Extra-articular causes of knee pain include; hip pathology, lumbar spine degenerative disease or radicular symptoms, focal neuropathy, vascular disease, and chronic regional pain syndrome. Intra-articular causes of knee pain: infection, crepitation/clunk, patella osteonecrosis, patella mal-tracking, soft tissue imbalance, malalignment, arthrofibrosis, component loosening, implant wear, ilio-tibial band irritation, and bursitis. Other causes of pain to rule out are component overhang with soft tissue irritation, recurrent hemarthrosis secondary to synovial impingement or entrapment, non-resurfaced patella, and metal sensitivity. A careful history may reveal previous knee surgeries with delayed healing or prolonged drainage, chronology of sign and symptoms, co-morbid medical conditions, jewel or metal sensitivity. Physical exam should help with specific signs in the operated knee. Targeted local anesthetic blocks are helpful and response to lumbar sympathetic blocks determines presence of CRPS. Lab tests are important: ESR, CRP, WBC, aspiration with manual cell count and diff, leucocyte esterase dipstick, RA titers, metal derm patch testing, nuclear scans, CT best for rotational malalignment, and MARS MRI. More recently patient satisfaction as an outcome measure has shown TKA results not satisfactory in 11- 18% of patients. A discordance of patient vs. surgeon satisfaction exists so the following factors may help improve this: correct patient selection, establishing and correlating surgeon-patient expectations, peri-operative optimization of patient co-morbidities to help avoid preventable complications, use of pre-operative and post-operative pathways. Satisfaction rates can best be improved by addressing the previous points with patients prior to TKA surgery


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_15 | Pages 51 - 51
1 Aug 2017
Jones R
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TKA is one of the most common orthopaedic operations performed worldwide and it is largely successful in pain relief and functional recovery. However, when pain persists post-operatively the thorough evaluation must be instituted. Extra-articular causes of knee pain include; hip pathology, lumbar spine degenerative disease or radicular symptoms, focal neuropathy, vascular disease, and chronic regional pain syndrome. Intra-articular causes of knee pain: infection, crepitation/ clunk, patella osteonecrosis, patella mal-tracking, soft tissue imbalance, malalignment, arthrofibrosis, component loosening, implant wear, ilio-tibial band irritation, and bursitis. Other causes of pain to rule out are component overhang with soft tissue irritation, recurrent hemarthrosis secondary to synovial impingement or entrapment, non-resurfaced patella, and metal sensitivity. A careful history may reveal previous knee surgeries with delayed healing or prolonged drainage, chronology of sign and symptoms, co-morbid medical conditions, jewel or metal sensitivity. Physical exam should help with specific signs in the operated knee. Targeted local anesthetic blocks are helpful and response to lumbar sympathetic blocks determines presence of CRPS. Lab tests are important: ESR, CRP, WBC, aspiration with manual cell count and diff, leukocyte esterase dipstick, RA titers, metal derm patch testing, nuclear scans, CT best for rotational malalignment,, and MARS MRI. More recently patient satisfaction as an outcome measure has shown TKA results not satisfactory in 11 – 18% of patients. A discordance of patient vs. surgeon satisfaction exists so the following factors may help improve this: correct patient selection, establishing and correlating surgeon-patient expectations, peri-operative optimisation of patient comorbidities to help avoid preventable complications, use of pre- and post-operative pathways. Satisfaction rates can best be improved by addressing the previous points with patients prior to TKA surgery


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_II | Pages 106 - 106
1 Feb 2003
Harvey JR Barrett DS
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There is a recognised incidence of anterior knee pain following Anterior Cruciate Ligament (ACL) reconstruction using a patella tendon autograft. This study examined two group of patients both pre ACL ligament reconstruction and post ACL reconstruction using patella tendon grafts to define if anterior knee pain is a result of patella tendon harvest or a primary consequence of an ACL injury. The two groups of patients were best matched for age, sex and physical activity. The pre-operative group of twenty-five patients had a confirmed ACL rupture and exhibited symptoms of instability requiring an ACL reconstruction. The operative group of twenty-five patients were a minimum of a year post operation. The graft was harvested by an open procedure and the graft bone blocks were secured with interference screws. The patients’ anterior knee pain score was assessed using the Shelbourne scoring system that evaluates knee function in relation to anterior knee pain using five parameters. The maximum score is 100. The scores were compared using the unpaired student test. There was no significant age difference between the two groups, preoperative group age 32. 2 years (range 22 to 46) and postoperative age 34. 8years (range 19 to 48). The mean anterior knee pain score for the preoperative group was 71. 6 (49 to 100), the postoperative group was 77. 7 (45 to 100), this was not significantly different. We found no significant difference in knee function due to anterior knee pain between the two groups. Studies have shown significant anterior knee pain following hamstring reconstruction (Spicer). This study shows anterior knee pain in the ACL deficient knee is present prior to surgery. We conclude that patella tendon autografts produce no significant incidence of anterior knee pain post surgery


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XVII | Pages 26 - 26
1 May 2012
Judd S Shaju A Keogh P Kenny P O'Flanagan S
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Introduction. A comprehensive met-analysis of anterior knee pain post intramedullary nailing of the tibia was performed by Katsoulis et al in 2006. The principle findings were that 47.4% of patients had anterior knee pain at 2 years post tibial nailing. Worse results were found following a patella tendon splitting approach when compared with a medial para-patellar tendon approach. These conclusions were drawn from 20 studies including 1460 patients. Currently both approaches to the proximal tibia for nailing are used at JCMH Blanchardstown. A retrospective study was performed to compare the results of tendon splitting and tendon sparing approaches to tibial nails and to compare the results of JCMH with those stated in literature. Method. Patients who underwent tibial nailing in 2007 and 2008 were identified using the hospital coding system. Those patients who were treated under the care of Mr Kenny had a medial para-tendinous approach and those treated the care of Mr O'Flanagan and Mr Keogh had a tendon splitting approach. Apart from the approach the nailing technique using the Trigen Knee Nail and the post operative physiotherapy protocol were identical. Follow up included questions regarding knee pain and return to previous function. Specifically: Knee pain that affects daily life, Knee pain on kneeling, Knee pain on ascending or descending stairs, Return to work and Return to sports or active hobbies. Results. 61 patients were treated with intra-medullary nailing between 2007 and 2008 43 were available for follow for the purposes of this study (70 %). 25 had nails inserted via a tendon splitting approach and 18 via a tendon sparing approach. Only 5% of patients had knee pain that affected daily life, 16 % had pain on kneeling, 90% of patients who were previously at work returned to work and 75% of patients who were previously engaged in sports were able to return to these activities. Discussion. These results are significantly better than the figures stated in literature in terms of knee pain, return to work and sports. There was no significant difference between the 2 approaches to the tibia again in contradiction of available literature


The Journal of Bone & Joint Surgery British Volume
Vol. 88-B, Issue 7 | Pages 905 - 908
1 Jul 2006
Hetsroni I Finestone A Milgrom C Sira DB Nyska M Radeva-Petrova D Ayalon M

Excessive foot pronation has been considered to be related to anterior knee pain. We undertook a prospective study to test the hypothesis that exertional anterior knee pain is related to the static and dynamic parameters of foot pronation. Two weeks before beginning basic training lasting for 14 weeks, 473 infantry recruits were enrolled into the study and underwent two-dimensional measurement of their subtalar joint displacement angle during walking on a treadmill. Of the 405 soldiers who finished the training 61 (15%) developed exertional anterior knee pain. No consistent association was found between the incidence of anterior knee pain and any of the parameters of foot pronation. While a statistically significant association was found between anterior knee pain and pronation velocity (left foot, p = 0.05; right foot, p = 0.007), the relationship was contradictory for the right and left foot. Our study does not support the hypothesis that anterior knee pain is related to excessive foot pronation


Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_8 | Pages 121 - 121
1 May 2014
Blaha J
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Anterior knee pain is a frequent complaint of dissatisfied total knee arthroplasty patients. We hypothesize that the need to use the extensor mechanism to stabilise the knee during activity is a cause of anterior knee pain. Studies have shown that TKA patients often walk with a “quadriceps avoidance” gait, which may explain the phenomenon of anterior knee pain. Most TKA prostheses are designed to allow AP motion. This feature in knee implant design is to prevent the “kinematic conflict” that was predicted with the crossed four-bar-link model of knee motion, which holds that progressive posterior contact of the femur on the tibia (rollback) with flexion was obligatory for knee range of motion. It has been stated that preventing this motion overly “constrained” the knee and could lead to loosening and wear. Paradoxical motion has been seen with video fluoroscopy in knees after TKA. This motion is an anterior translation of the femur on the tibia early in knee flexion and is called paradoxical because it occurs opposite to the expected rollback. In fact, paradoxical motion is a consequence of the “unconstrained” articulation of the femoral component on the tibial component. During gait, just after heel strike as the foot is assuming a flat position on the floor, there is a significant vector of force from posterior to anterior. This vector has been calculated as 33% of body weight for walking at normal speed and could lead to a significant displacement of the femur forward on the tibia. It is countered by 1) the slope of the proximal tibia; 2) the articulation of the femur in the concavity of the tibial (with the firmly attached meniscus that deepens the concavity) on the medial side; and 3) the body mass vector combined with that of the contracting quadriceps. If a total knee prosthesis allows the femur to move forward, the posterior-to-anterior force just after heel strike acts to move the femur forward on the tibia (paradoxical motion). The patient, in an attempt to stabilise the knee, uses increased quadriceps contraction to prevent the forward motion of the femur. The forces required are significant and are not only found in the patella-femoral articulation but all through the retinaculum that covers the anterior part of the femur. As the extensor mechanism tires, patients begin using a quadriceps avoidance gait to adapt to the weakening extensor, and after a period of activity, the stress on the retinaculum leads to pain. AP stability can be improved through implant design by preventing AP motion through conformity of the femoral and tibial components. We have used a medially conforming ball-in-socket prosthesis as a revision component for patients with anterior knee pain, and have achieved resolution of the pain. Patients demonstrate a “posterior sag” at approximately 20 degrees of flexion (the degree of flexion that has the maximum posterior-to-anterior force during gait). When treated with a brace appropriate for stabilisation of the knee after PCL reconstruction, patients experienced a marked decrease in symptoms and this predicts a good result from revision surgery


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_3 | Pages 152 - 152
1 Jan 2016
Sekiya H Takatoku K Takada H Kanaya Y Sasanuma H
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From October 2005 to March 2014, we performed 46 arthroscopic surgeries for painful knee after knee arthroplasty. We excluded 16 cases for this study such as, unicompartmental knee arthroplasty, infection, patellar clunk syndrome, patellofemoral synovial hyperplasia, aseptic loosening, and follow-up period after arthroscopic surgery less than 6 months. Thirty cases matched the criteria. They had knee pain longer than 6 months after initial total knee arthroplasty (TKA), they had marked tenderness at medial and/or lateral tibiofemoral joint space, and also they complained walking pain with or without resting pain. Twenty one cases had initial TKA at our institute. In consideration of total number of TKA (n=489) in the period at our institute, incident rate of painful knee after initial TKA was 4.3%. Of 30 cases, 3 cases were male, and 27 cases were female. Types of implant were 4 in cruciate retaining type, 1 in cruciate substituting type, and 25 in posterior stabilized type. Age at the arthroscopy was 72 years old (51–87 years old), and period form initial TKA to pain perception was 18 months(1 – 144 months), and period from initial TKA to arthroscopic surgery was 29 months (6 – 125 months), and follow-up period after arthroscopy was 36 months (6 – 93 months). All arthroscopic debridement were performed through 3 portals, anteromedial, anterolateral, and proximal superomedial portal. Scar tissue impingements more than 5 mm wide were found in 87% of the cases both medial and lateral femorotibial joint spaces. Infrapatellar fat pad were covered with whitish scar tissue in all cases, and the scar tissue were connecting with the scar tissue which found at medial or lateral femorotibial joint spaces. We removed all scar tissue with motorized shaver or punches. At final follow-up, complete pain free in 63%, marked improvement in 3%, half improvement in 20%, slight improvement in 3%, and no change in 10% of the cases. Previously in the literatures, two reasons of the pain after total knee arthroplasty had been reported, patellar clunk syndrome, and patellar synovial hyperplasia. All cases reported this study had marked tenderness at tibiofemoral joint space. It was difficult to explain the tenderness by previously reported pathological mechanisms. We had to find another pathological mechanism to explain the pain of our cases. Painful knee due to scar tissue formation known as “infrapatellar contracture syndrome” after anterior cruciate ligament reconstruction surgery was previously reported. We hypothesized similar scar tissue formation should occur after TKA that caused painful knee. Continuity of the solid scar tissue between infrapatellar fat pad with the scar tissue at tibiofemoral joint space should be the cause of impingement at femorotibial joint even small size of scar tissue. From this study, we have to recognize that painful knee after TKA is not infrequent complication. And, if we could deny infection, and aseptic loosening in painful knee after TKA, arthroscopic debridement was good option to solve the pain. We could expect improvement of the pain more than half in 87% of cases


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_10 | Pages 99 - 99
1 May 2016
van de Groes S Kreemers-Van De Hei K Koeter S Verdonschot N
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Introduction. Special high-flexion prosthetic designs show a small increase in postoperative flexion compared to standard designs and some papers show increased anterior knee pain with these prosthesis. However, no randomised controlled trails have been published which investigate difference in postoperative complaints of anterior knee pain. To assess difference in passive and active postoperative flexion and anterior knee pain we performed a randomized clinical trial including the two extremes of knee arthroplasty designs, being a high flex posterior stabilized rotating platform prosthesis versus a traditional cruciate retaining fixed bearing prosthesis. We hypothesised that the HF-PS design would allow more flexion, due to increased femoral rollback with less anterior knee pain than the CR design. We specifically assessed the following hypotheses:. Patients have increased flexion after HF-PS TKA compared to CR TKA, both passive and active. Patients show an increased femoral rollback in the HF-PS TKA as compared to the CR TKA. Patients receiving a HF-PS TKA design report reduced anterior knee pain relative to those receiving the CR TKA. Methods. In total 47 patients were randomly allocated to a standard cruciate retaining fixed bearing design (CR) in 23 patients and to a high-flexion posterior stabilized mobile bearing design (HF-PS) in 24 patients. Preoperative and one year postoperative we investigated active and passive maximal flexion. Furthermore, we used the VAS pain score at rest and during exercise and the Feller score to investigate anterior knee pain. A lateral roentgen photograph was used to measure femoral rollback during maximal flexion. Results. The HF-PS did show a significantly higher passive postoperative flexion; 120.8° (SD 10.3°) vs. 112.0° (SD 9.5°) for the CR group (p=0.004). The active postoperative flexion, VAS-pain score and Feller score did not show significant differences between both groups. Sub analysis with the HF-PS group showed a higher VAS-pain for the patients achieving ≥130° of flexion; 30.5 (SD 32.2) vs. 12.2 (SD 12.5) (p=0.16). The rollback was significantly lower in the CR group compared to the HF-PS group; 4.4 (SD 3.0) vs. 8.4 (SD 2.1). Conclusion. The present study showed a significant higher passive flexion in the Posterior Stabilised-High Flexion mobile bearing compared to a Cruciate Retaining fixed bearing prosthesis. However, this difference disappeared when comparing active flexion. The difference in passive flexion was probably related to a significantly lower rollback causing impingement in the CR prosthesis. No difference in anterior knee pain was found between both groups. However, a suggestion is raised that achieving high-flexion might lead to more patellofemoral complaints/anterior knee pain


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_III | Pages 423 - 424
1 Jul 2010
Toumi H Best T Forster M Fairclough J
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Purpose: A relationship between vastus medialis oblique (VMO) strength and anterior pain and disability has been suggested. A biomechanical protocol was used to access the deficiency of the quadriceps muscles in patients with anterior knee pain. Methods and Results: A biomechanical evaluation was conducted on 54 patients with anterior knee pain (34 females and 20 males). All patient x-rays were normal through interpretation by a blinded radiologist. A Kistler force plate, a VICON motion analysis system and surface electromyography were used to quantify biomechanical function during isometric, walking and squatting exercises. For 42 of the 54 (78%) subjects, during isometric and walking exercises we observed that activation of the VMO, rectus femoris (RF) and vastus lateralis (VL) muscles of the symptomatic leg was not significantly different from those of the asymptomatic leg (p< 0.01). However, for 31 patients (57%) during the eccentric phase of the squat exercises, the symptomatic leg presented with high activation of VL compared to VMO and RF (p< 0.01). During the concentric phase, 45 patients (83%) presented with higher activation of the VL compared to the VMO. Conclusion: VMO activity during squatting for the symptomatic patient with anterior knee pain leg differs fundamentally during walking and isometric exercise compared to squatting tasks. Moreover, the relative contribution of the VL compared to the VMO during the eccentric phase of the squat exercises was different to those recorded during the concentric phase. Therefore, we suggest that maximal isometric and or isokinetic exercises are not sufficient to access the quadriceps function in relation to anterior knee pain. A thorough biomechanical assessment, including functional testing to reproduce the patient’s pain and locate the nature of the symptoms is suggested


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_III | Pages 267 - 267
1 Nov 2002
Boyd K Tippett R Moran C
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Aim: To assess the prevalence of anterior knee pain after intramedullary nailing of the tibia and its socioeconomic impact. Methods: A retrospective, study of 251 consecutive tibial intramedullary nailings in 248 patients, aged less than 60 years at the time of injury. The minimum follow-up period was five years and the patients were assessed using a questionnaire and the Lysholm knee score. Results: The mean follow-up was 7.9 years. Anterior knee sensory disturbance was reported by 58% of patients. Anterior knee pain (AKP) was reported by 47%. This interfered with activities of daily living in 37%, work in 36% and sport in 57%. Pain on kneeling was mild in 54%, moderate in 34% and severe 12%. AKP improved with time in 73% patients and became worse in 4%. The Lysholm score rated 41% knees as excellent, 19% as good, 26% as fair and 14% as poor. Eighty-six percent of the patients returned to work. The presence of anterior knee pain prevented return to previous work in 10%. The type of work performed before and after injury respectively were; sedentary 26%/29%, walking-based 20%/27%, manual 38%/37%, heavy manual 16%/7%. Conclusions: Anterior knee pain persisted in 47% of patients after intramedullary nailing of the tibia. There was some decrease in symptoms with time and the majority of patients were able to return to work. However, anterior knee pain caused a significant disability in a small number and all patients should be warned of this problem before this type of surgery


The Journal of Bone & Joint Surgery British Volume
Vol. 91-B, Issue 3 | Pages 344 - 350
1 Mar 2009
Luyckx T Didden K Vandenneucker H Labey L Innocenti B Bellemans J

The purpose of this study was to test the hypothesis that patella alta leads to a less favourable situation in terms of patellofemoral contact force, contact area and contact pressure than the normal patellar position, and thereby gives rise to anterior knee pain. A dynamic knee simulator system based on the Oxford rig and allowing six degrees of freedom was adapted in order to simulate and record the dynamic loads during a knee squat from 30° to 120° flexion under physiological conditions. Five different configurations were studied, with variable predetermined patellar heights. The patellofemoral contact force increased with increasing knee flexion until contact occurred between the quadriceps tendon and the femoral trochlea, inducing load sharing. Patella alta caused a delay of this contact until deeper flexion. As a consequence, the maximal patellofemoral contact force and contact pressure increased significantly with increasing patellar height (p < 0.01). Patella alta was associated with the highest maximal patellofemoral contact force and contact pressure. When averaged across all flexion angles, a normal patellar position was associated with the lowest contact pressures. Our results indicate that there is a biomechanical reason for anterior knee pain in patients with patella alta


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 255 - 255
1 Mar 2004
Rajaratnam S Rogers A McKee A Butler-Manuel A
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Aims: Anterior knee pain is a common complaint of mixed aetiology, and in many cases no demonstrable cause is identified. For patients with persistant anterior knee pain, tibial tubercle transfer (TTT) can be a surgical option. The aim of this study is to assess the effectiveness of TTT for chronic anterior knee pain resistant to conservative treatment. Method: All patients with arthroscopically proven Chondromalacia patellae (CMP) without clinical evidence of patella instability, who have failed to respond to conservative treatment such as physiotherapy were included in the trial. They underwent TTT with a modified Fulkerson technique and then routine post-operative care with a cricket pad splint for 2–4 weeks. Pre and post-operative scores were obtained using a Kujala patello-femoral score, a visual analogue score for pain and a patient satisfaction score. The Outerbridge grading was used to score the severity of CMP at arthroscopy. Results: There were 50 TTT’s followed up (7 staged bilaterals) with a mean follow up of 32.4 months (5–88 months). There were significant improvement in the pre-operative and post-operative Kujala (p> 0.001) and visual analogue pain scores (p> 0.001). Of the 50 TTT’s 70% had an excellent or good result and 30% a fair or poor result. Moreover 76% claimed that they would have the same operation again for their condition. There was no significant correlation between Outerbridge grading and post-operative outcome. Complications include late anterior knee pain (10 cases), superficial wound infection (1 case), non-union of osteotomy (1 case) and tuberosity fracture (1 case). Conclusion: Anteromedial tibial tubercle transfer is a reliable and effective treatment for peristant anterior knee pain


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_12 | Pages 9 - 9
1 Jun 2016
Conchie H Clark D Metcalfe A Eldridge J Whitehouse M
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There is a lack of information about the association between patellofemoral osteoarthritis (PFOA) and both adolescent Anterior Knee Pain (AKP) and previous patellar dislocations. This case-control study involved 222 participants from our knee arthroplasty database answering a questionnaire. 111 patients suffering PFOA were 1:1 matched with a unicompartmental tibiofemoral arthritis control group. Multivariate correlation and binary logistic regression analysis was performed, with odds ratios (ORs) and 95% confidence intervals (CIs) calculated. This analysis helps us assess the effect of both variables whilst adjusting for major confounders, such as previous surgery and patient-reported instability. An individual is 7.5 times more likely to develop PFOA if they have suffered adolescent AKP (OR 7.5, 95% CIs 1.51–36.94). Additionally, experiencing a patellar dislocation increases the likelihood of development of PFOA, with an adjusted odds ratio of 3.2 (95% CIs 1.25–8.18). A 44-year difference in median age of first dislocation was also observed between the groups. This should bring into question the traditional belief that adolescent anterior knee pain is a benign pathology. Patellar dislocation is also a significant risk factor. These patients merit investigation, we encourage clinical acknowledgement of the potential consequences when encountering patients suffering from anterior knee pain or patellar dislocation


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 468 - 468
1 Sep 2009
Sadoghi P Glehr M Schuster C Kränke B Schöllnast H Pechmann M Quehenberger F Windhager R
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Whereas thermography has already been used as an assessment of disease activity in some kinds of inflammatory arthritis, it is a new method for objektive pain evaluation in patients with joint prosthesis. To our knowledge, no study has tested the correlation between increase of temperature and anterior knee pain with total knee prosthesis yet. Thirteen patients were included in this study who suffered from anterior knee pain of the retinaculum patellae with total knee prosthesis. The patients were asked to walk 3 km before entering a room which was cooled down to 20 degrees Celsius. A black 1 cm times 4.5 cm square stripe was attached on the diameter of the patella and the patients rested for 20 minutes to cool down before thermographic fotos were taken from 90 degrees, 45 degrees, frontal medial and lateral. The evaluation of temperature difference of each side was performed by marking a 1cm times 2cm square field rectangular around the black stripe and comparing it with a reference point of the same size 3 cm distal of the field. The patients were compared with thirteen others, not suffering from anterior knee pain. Statistical analysis was performed using a t- test and a p value < 0.05 was considered to be significant. The temperature differences between the rectangular field and the reference point increased significantly on the medial (p= 0.00037) or lateral (p= 0.000002) pain side of the knee. The thirteen knees with knee pain had significantly higher temperature differences between medial and lateral temperature differences, than the knees without knee pain. We demonstrate a significant correlation between anterior knee pain and an increase of superficial skin temperature around the retinaculum patellae. To our knowledge, this is the first report of an objective assessment of pain of the retinaculum patellae with total knee prosthesis


The Journal of Bone & Joint Surgery British Volume
Vol. 66-B, Issue 5 | Pages 685 - 693
1 Nov 1984
Fairbank J Pynsent P van Poortvliet J Phillips H

Mechanical abnormalities of the patellofemoral joint are among the many causes that have been suggested for adolescent knee pain. This study seeks to identify these factors. Measurements of joint mobility and lower limb morphology were made on 446 pupils at a comprehensive school, 136 of whom had suffered knee pain in the previous year. The pupils with symptoms enjoyed sporting activities significantly more than their symptom-free contemporaries. Joint mobility, the Q-angle, genu valgum and anteversion of the femoral neck were not significantly different between those pupils with and those without anterior knee pain. Data on lower limb morphology of normal adolescents are presented. Examination of 52 hospital outpatients aged 13 to 36 years with anterior knee pain produced results comparable with those for the pupils. It is concluded that chronic overloading, rather than faulty mechanics, is the dominant factor in the genesis of anterior knee pain in adolescent patients


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIX | Pages 92 - 92
1 Sep 2012
Papanna M Al-Hadithy N Yasin N Sundararajan S
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Aim. To determine if the location and pattern of knee pain as described by the patients using the knee pain map was comparable with the intra articular pathology found on arthroscopy as well as to facilitate diagnosis based on pain. Methods. There were fifty five consecutive patients with acute and chronic knee pain participating in the study and they subsequently underwent arthroscopy of the knee joint as therapeutic or diagnostic procedure in day surgery. Those patients with extra articular pathologies, referred pain hip, back and foot were excluded from the study. All the participants were consented for the study; subjective data was recorded on the standardised knee pain map that included visual analogue pain scale preoperatively on the day of admission for arthroscopy. The findings of the arthroscopy including EUA were recorded on the on standard arthroscopy forms used in our department by the operating surgeon. Results. Patients on the knee pain map most often recorded sharp/stabbing pain (72%), followed by diffuse dull pain (14.5%), mixed dull and sharp pain (10 %) and burning pain (3.5%). 82% of the localising pain pattern recorded on the knee pain map by the patients corresponded to the intra articular lesion found during knee arthroscopy. 18 % of the pain mapping location and pattern was not very specific to the intrarticular arthroscopic lesions. Conclusions. The results from our study indicate, majority of the patients could map the knee pain location and pattern correlating to the knee arthroscopic findings. Furthermore, the knee pain mapping can be used as a reliable tool to assist the clinician to determine the specific knee pain patterns correlating with intra-articular lesion


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XVIII | Pages 73 - 73
1 May 2012
Papanna MMC Yasin MN Sundararajan MS Kim M
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Objective of the study. To determine if the location and pattern of knee pain as described by the patients using the knee pain map was comparable with the intra articular pathology found on arthroscopy as well as to facilitate diagnosis based on pain. Methods. There were Sixty consecutive patients with acute and chronic knee pain participating in the study and they subsequently underwent arthroscopy of the knee joint as therapeutic or diagnostic procedure in day surgery. Those patients with extra articular pathologies, referred pain hip, back and foot were excluded from the study. All the participants were consented for the study; subjective data was recorded on the standardised knee pain map that included visual analogue pain scale preoperatively on the day of admission for arthroscopy. The findings of the arthroscopy including EUA were recorded on the on standard arthroscopy forms used in our department by the operating surgeon. Results. Patients on the knee pain map most often recorded sharp/stabbing pain (72%), followed by diffuse dull pain (14.5%), mixed dull and sharp pain (10 %) and burning pain (3.5%). 78 % of the localising pain pattern recorded on the knee pain map by the patients corresponded to the intra articular lesion found during knee arthroscopy. 18 % of the pain mapping location and pattern were not very specific to the intrarticular arthroscopic lesions and the rest were non specific. Conclusions. The majority of the patients could map the knee pain location and pattern correlating to the knee arthroscopic findings. The results from our study indicate that knee pain mapping can be used as a reliable tool to assist the clinician to determine the specific knee pain patterns correlating with discrete pathologic findings knee intra articular lesion


Bone & Joint Research
Vol. 1, Issue 8 | Pages 167 - 173
1 Aug 2012
Jack CM Rajaratnam SS Khan HO Keast-Butler O Butler-Manuel PA Heatley FW

Objectives. To assess the effectiveness of a modified tibial tubercle osteotomy as a treatment for arthroscopically diagnosed chondromalacia patellae. Methods. A total of 47 consecutive patients (51 knees) with arthroscopically proven chondromalacia, who had failed conservative management, underwent a modified Fulkerson tibial tubercle osteotomy. The mean age was 34.4 years (19.6 to 52.2). Pre-operatively, none of the patients exhibited signs of patellar maltracking or instability in association with their anterior knee pain. The minimum follow-up for the study was five years (mean 72.6 months (62 to 118)), with only one patient lost to follow-up. Results. A total of 50 knees were reviewed. At final follow-up, the Kujala knee score improved from 39.2 (12 to 63) pre-operatively to 57.7 (16 to 89) post-operatively (p < 0.001). The visual analogue pain score improved from 7.8 (4 to 10) pre-operatively to 5.0 (0 to 10) post-operatively. Overall patient satisfaction with good or excellent results was 72%. Patients with the lowest pre-operative Kujala score benefitted the most. Older patients benefited less than younger ones. The outcome was independent of the grade of chondromalacia. Six patients required screw removal. There were no major complications. Conclusions. We conclude that this modification of the Fulkerson procedure is a safe and useful operation to treat anterior knee pain in well aligned patellofemoral joints due to chondromalacia patellae in adults, when conservative measures have failed


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 161 - 161
1 Mar 2010
Itokawa T Kondo M Tsumura H Fujii T Azuma T Tomari K Kadoya Y
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Achieving deep flexion of knee after total knee arthroplasty (TKA) is particularly desirable in some Asian and Middle Eastern who have daily or religious customs typically use full knee flexion. After TKA, some patients complained about anterior knee pain during deep knee flexion. We evaluated the efficacy of arthroscopic fat pad resection in a series of patients suffering from anterior knee pain associated with high flexion achievement after TKA. The efficacy of fat pad resection via arthroscopy for treating anterior knee pain associated with high flexion angle (average = 133.1°) was evaluated in eight knees of eight patients among 207 knees performed between 1996 and 1999. The mean age of patients was 71.1 years when the primary TKA was performed. All implatants were posterior stabilized type (IB-II, Nexgen PS and LPS). The symptom of anterior knee pain during deep knee flexion developed within one year after TKA in all cases. In addition to pain in eight knees, two patients have crepitation as the knee was flexed and extended and three patients had hydrarthrosis. Impingement and fibrosis of fat pad were confirmed, and fibrous structures were removed by arthroscopy. Before arthroscopy, the symptom obviously subsided after injection of local anesthesia into infrapatellar fat pad. Patellar clunk syndrome is also soft tissue impingement and suprapatellar fibrous nodule becomes entrapped intercondylar notch on the femoral component during knee flexion. On this point, these cases does not cause by patellar clunk syndrome. After fat pad resection, the symptom disappeared, and keeps symptom-free after a mean follow-up of six years five months in all cases. Any complications following fat pad resection, such as patella baja and necrosis, were not experienced. Those cases achieving higher flexion angle tended to experience severe pain and shorter time interval between TKA and arthroscopic surgery, suggesting impingement of the infrapatellar fat pad is closely related to deep flexion after TKA. These results demonstrate that the anterior knee pain due to repetitive infrapatellar fat pad impingement is one of the complications during deep knee flexion after TKA, and the arthroscopic fat pad resection is useful to relief the anterior knee pain. Because of our experience with patients encountering anterior knee pain, we have begun to remove 70 to 80% of the fat pad during the primary TKA procedure since 1999, and until today, none developed anterior knee pain thought to be associated with fat pad impingement, patellar baja nor patellar necrosis. We suggest that fat pad resection is necessary to prevent the anterior knee pain due to fat pad impingement during deep flexion in TKA


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XL | Pages 205 - 205
1 Sep 2012
Vandenneucker H
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The prevalence of anterior knee pain in the general population is relatively high. Patellar height, and more specific patella alta, is one of the several factors that have been associated with anterior knee pain, but the precise mechanism by which patella alta leads to a less favourable situation in terms of patellofemoral contact force, contact area and contact pressure, is poorly understood. The recent availability of validated dynamic knee simulators and advances in the analysis of contact force and area, give us today the possibility to study the influence of patellar position and patellar height on patellofemoral biomechanical characterisitics. Simulating a knee squat in different configurations with variable predetermined patellar height, reveals a clear association of patella alta with the highest maximal patellofemoral contact force and contact pressure, probably as a consequence of the delay in tendofemoral contact. When averaged across all flexion angles, the normal height of the patella seems to be the most optimal position in terms of contact pressures. This may provide a biomechanical explanation for anterior knee pain in young patients with patella alta and in older patients following total knee prosthesis resulting in an altered patellar position in terms of height


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 352 - 352
1 Jul 2011
Evangelopoulos D Kohl S Krueger A Hartel M Kohlhof H Roeder C Eggli S
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Total knee arthroplasty (TKA) disturbs patellar blood flow, an unintended accompaniment to TKA that may be a cause for postoperative anterior knee pain. We compared patellar blood flow before and after medial parapatellar arthrotomy to pre- and postoperative anterior knee pain scores to ascertain whether disrupted patellar blood flow correlates with anterior knee pain following TKA. Blood flow measurements were performed at full extension and at 30°, 60°, 90° and 110° of flexion prior to and after medial arthrotomy in 50 patients (21 male, 29 female; mean age 73.1±8.6 years) undergoing TKA. Anterior knee pain was assessed using the pain intensity numeric rating scale. A significant decrease in blood flow was detected at 60°, 90°, and 110° of flexion (p values: 0.00314,< 0.0001,< 0.0001 respectively). The medial arthrotomy did not have a statistically significant influence on patellar blood flow in the Students’ t-test (margin of significance p& #61603;0.05) Nineteen patients exhibited an average 14% (range 1%–54%) increase in patellar blood perfusion at knee flexions of 90° and 110° after medial arthrotomy (p value: 0.32) Prior to TKA, 16 of the 50 patients (32%) complained of anterior knee pain (average NRS 7.12, range 5–10). At 6-month follow up, 4 of the 16 patients (25%) complained of moderate anterior pain (average NRS 5.7, range 5–6), while 8 of 16 (50%) patients reported discomfort (average NRS 3.5, range 2–4) around the patella. No statistically significant correlation was found between intraoperative findings on patellar blood flow and the presence of anterior knee pain


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 404 - 404
1 Jul 2008
Lakshmanan P McCaskie A Gerrand C
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Introduction: Short term pain or discomfort after a knee replacement (TKR) is not uncommon, and is usually attributed to the surgical procedure. In this case report, we describe an unusual cause of knee pain following total knee replacement, and remind the reader of the need for a thorough assessment. Case Report: A 76 year-old male presented with pain in the knee and shin seven months following a TKR on the same side. The pain was dull, aching and constant in nature. There was no other significant past medical history. Pre-operative and immediate postoperative radiographs did not reveal any other abnormality. Clinical examination revealed no evidence of infection, and the motion in the knee ranged from 0–100 degrees. Radiographs revealed a lytic lesion in the proximal tibia just distal to the tibial prosthesis. Further investigations confirmed a diagnosis of renal carcinoma with bone metastases, with one of the lesions appearing in the proximal tibia. The lesion was treated with intralesional curettage, cementing and plate osteosynthesis. The knee pain improved and the mobility was restored. Follow-up radiographs at 6 months showed no evidence of local recurrence. Discussion: Knee pain following TKR may be attributed to the surgery or the knee implant. However, it is important to keep an open mind about the diagnosis. Local hyperaemia in the metaphysis of proximal tibia following TKR may have resulted in the seeding of metastasis. We elected for primary stabilization of the metastasis with cement and plate, rather than revision of the tibial component with a long intramedullary stem. As a result, rehabilitation was rapid and the risks of revision of the knee prosthesis were avoided


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_II | Pages 118 - 119
1 Feb 2003
Gill P Keast-Butler O Parikh M Butler-Manuel A
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The aim of this study was to assess the outcome of patients who underwent ElmslieTrillat antero-medial tibial tubercle transfer for treatment of persistent symptomatic anterior knee pain due to chondromalacia patellae. We performed a prospective analysis of 23 patients who underwent Elmslie-Trillat antero-medial tibial tubercle transfers over a five year period for chronic anterior knee pain and an arthroscopic diagnosis of chondromalacia patellae. All patients who presented with anterior knee pain underwent an initial period of physiotherapy and all patients whose symptoms persisted following physiotherapy underwent arthroscopic assessment. Patients who continued to experience debilitating symptoms despite this initial treatment and who also had a diagnosis of chondromalacia patellae from arthroscopic assessment were listed for an Elmslie-Trillat tibial tubercle anteromedialisation. Patients who gave a history of instability or dislocation were excluded. The average age of patients undergoing surgery was 34 years (21–48 years) and the average time between arthroscopic diagnosis and surgery was 14 months. All patients who underwent surgery had pre and post operative KuJala patellofemoral scoring. The average pre-operative score was 54 (30–78) and post operative score 76 (46–100). The average post operative assessment was 25 months (6–62 months). Twenty one patients had improved post operative scores with one having a worse score and one score remaining unchanged following surgery. Nineteen patients felt that their symptoms had improved, three felt that there had been no change and one felt that they were worse after surgery. When asked if the improvement in symptoms had been worthwhile nineteen stated that they would undergo surgery again if in the same situation and four stated that they would not. The treatment of symptomatic chondromalacia patellae remains a challenge. Although a more selective approach to individuals with anterior knee pain is widely advocated in the literature this study demonstrates that good results can still be achieved in patients treated empirically with a tibial tubercle anteromedialisation


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_1 | Pages 101 - 101
1 Feb 2015
Cameron H
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There are two types of pain, mechanical and non-mechanical. Mechanical pain hurts with movement/use, is not constant and is helped by morphine-type products. Non-mechanical pain is different. It is present 24 hours a day, often worse at night, and except for the pain of infection, is not relieved by morphine-type products. If the cause of mechanical pain can be determined, it can be corrected by an operation. The usual cause of postoperative mechanical knee pain nowadays is multifactorial, i.e. a combination of minor errors, none of which on their own would require revision. Non-mechanical pain, other than infection, is much more difficult to handle. The commonest cause is not really a pain complaint, it is disappointment due to a failure of expectation. It does not matter how often you tell patients, some patients still think they should step in a drive away. A lot of these failures of expectations become much more realistic by the end of year one. There are several other categories. Incipient osteoarthritis or sensitive people (The Princess and the Pea). If the pain complaints were severe with minimal arthritis, an operation is not likely to help. The patient on disability for no clear reason is unlikely to get a good result and Workmen's Compensation Board and motor vehicle accident patients are also a very bad prognostic sign and will often produce the postoperative painful knee. Preoperative use of large doses of morphine is also a very bad sign. It is not clear if it is the morphine, which influences the patient or the patient, who influences the morphine. There are several pain syndromes, some of which are purely psychiatric such as Conversion Disorders and Somatoform Pain Disorders. Treatment of purely psychiatric conditions should be a referral to a psychiatrist is in order. Complex regional pain syndrome is an organic pain disorder. Type 2 is causalgia or an actual nerve injury. This is unusual following knee replacement other than the odd drop foot, which even after recovery, leaves an area of dysaethesia on the dorsum of the foot. Type 1 used to be called reflex sympathetic dystrophy. This is not uncommon after total knee replacement. I managed to collect more than 40 cases. One problem is that the diagnosis to some extent is a diagnosis of exclusion. If the diagnosis can be made, then treatment is available including Cymbalta, Lyrica or Gabapentin. I have found most success with lumbar sympathetic blocks, but it is difficult to find someone, who can do these. Some patients have been treated with implantable electrical spinal stimulators with variable results. The current flavour of the month pain syndrome is called central sensitization. The theory is that if someone has pain for more than six months, then there will be changes in the brain, which will remain after the original pain goes away, hence, the title the pain in the brain syndrome. If this theory were correct, then we as arthroplasty surgeons have been collectively wasting our time for the last 40 years as no patient would have recovered. The likelihood, therefore, of this theory having any basis in reality is pretty remote. Fortunately, by the end of year one, the vast majority of our knee replacement patients are reasonably content with the procedure


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 551 - 551
1 Sep 2012
Wong F Przedlacka A Tan HB Allen P
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Introduction. Anterior knee pain is a common presentation of patello-femoral dysfunction and patients with this disorder represent a significant proportion attending a specialist knee clinic. There is an on-going debate as to the cause and best treatment for such patients. Previous studies on patella-femoral morphology have suggested patella maltracking plays an important part in the aetiology but there had been no studies correlating maltracking with articular cartilage change. Methods. We studied 147 consecutive patients (294 knees) aged between 10 and 63 presenting with anterior knee pain. All underwent MRI tracking scan of their knees as part of the routine investigations. We analysed the prevalence of maltracking with respect to gender, laterality and age groups, as well as patello-femoral articular cartilage changes. Results. 52% of patients were found to have maltracking, of which 75% were bilateral. Furthermore, 66% of patients with maltracking had radiological evidence of patellar articular cartilage changes, corresponding to 61% of 294 knees examined. While majority of these occur at lateral facet, a proportion of medial facet changes (16%) is also seen. More significantly, while 25% of knees from patients with maltracking under the age of 20 are found to have changes on the patella cartilage, this increases to 93% by the age of 50 or above, with step-wise increment per decade of age (p<0.01). Conclusion. Our results demonstrate a strong correlation between anterior knee pain symptoms, patella maltracking and changes in patello-femoral joint cartilages of varying severity. This has implications on the management of these patients and would suggest early correction of maltracking is indicated to prevent deterioration in the patello-femoral joint


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 74 - 75
1 Mar 2008
Sanders D MacLeod M Charyk-Stewart T Lydestad J Domonkos A Poon J
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Recovery after femur fractures is slow, despite rapid bone union. Causes of disability require investigation. Forty patients with isolated, diaphyseal femur fractures treated with antegrade locked intramedullary nailing were prospectively studied. Functional outcome was measured using the Western Ontario – McMaster University Osteoarthritis Index (WOMAC) and Short Musculoskeletal Functional Assessment (SMFA). Pain scores from the groin, buttock, thigh, and knee six months following the injury were correlated with functional outcome. Severity of pain was highest at the knee. Both knee and thigh pain had strong correlations with functional outcome measures following diaphyseal femur fractures. Further investigation into post-traumatic pain is warranted. This study was performed to compare pain at the knee, thigh, buttock and groin with functional outcome scores 6 months following femur fractures. Pain at the knee and thigh correlated with functional outcome measures. Many patients with femoral fractures have prolonged disability. Knee pain is common, severe, and correlates with functional outcome. Forty skeletally-mature patients with diaphyseal femoral fractures treated with locked antegrade intramedullary nails were prospectively enrolled. Exclusion criteria included polytrauma, ipsilateral injuries, metaphyseal extension, and pathologic fractures. Functional outcomes were assessed using the Western Ontario-McMaster University Osteoarthritis Index (WOMAC) and the Short Musculoskeletal Function Assessment (SMFA). Patients were instructed to record pain in the groin, buttock, thigh or knee of the fractured extremity on a 10-point visual analog scale. Patients reported more pain at the knee (3.7 ± 3.1), compared to the thigh (2.5 ± 2.7), buttock (1.7 ± 2.7), and groin (1.0 ± 1.7) (p=0.003). Pain and functional outcomes were plotted on scatter graphs and correlations performed using the Spearman rank test. Strongest correlations were noted between knee pain and WOMAC pain (ρ=0.748, p< 0.001), function (ρ=0.701, p< 0.001), and SMFA (ρ=0.733, p< 0.001); and between thigh pain and WOMAC pain (ρ=0.705, p< 0.001), stiffness (ρ=0.707, p< 0.001), function (ρ=0.731, p< 0.001), and SMFA (ρ=0.723, p< 0.001). Weaker correlations were noted between groin and buttock pain and functional outcomes. Knee pain is common and severe after femur fractures. Knee and thigh pain correlate with functional outcomes. Further investigation should be directed to this common problem. Funding: Funding from Synthes Canada, Smith and Nephew Richards Canada, and the Lawson Health Research Institute was received in support of this study


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_II | Pages 123 - 123
1 Feb 2012
Choudhary R Kulkarni S Barrett D
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We performed an advancement and medial transfer of the tibial tuberosity based on Fulkerson's principle to treat intractable anterior knee pain associated with patellofemoral maltracking diagnosed by dynamic MRI. Between January 1998 and July 2000 twenty-two patients had 28 knees operated for anterior knee pain. There were 4 men and 18 women with a mean age of 28 years (range 18-41). Indications for surgery were [a] failure to improve after six months of physiotherapy and [b] patellofemoral maltracking evident in dynamic MRI. Mean follow-up was for 37 months (23 – 42). Knee instability score modified by Fulkerson was employed for objective and subjective assessment. Objectively 22 (79%) knees achieved good to excellent results. Four knees (14%) had fair, and two (7%) had poor results. Excellent and very good results were seen in 20 knees. These patients were a younger age group (mean age 21 years) and had minimal degeneration (grade I-II) of the patellofemoral joints. Two patients achieved good results. One of them had moderate (grade III) and one minimal (II) arthritis. Three knees with fair results had advanced (grade IV or V) and one had moderate (grade III) arthritis. Out of two patients who had a poor result, one had advanced degeneration (grade V) that later required a patellofemoral joint resurfacing. The other was a 24 year old woman with grade II changes. She was treated by the pain therapy team. Anterior displacement of the tuberosity in the presented study was kept to 5 mm to avoid the possible complications of wound break down. The overall length and depth of the osteotomy was also reduced to minimise risk of fracture and commence early mobilisation. Based on our results there is a strong case of justification for Anteromedialisation of tibial tuberosity using a smaller length of osteotomy and lesser degree of anteriorisation in carefully selected patients with Patellofemoral arthralgia associated with maltracking patella


The Journal of Bone & Joint Surgery British Volume
Vol. 67-B, Issue 1 | Pages 36 - 38
1 Jan 1985
Sandow M Goodfellow J

Anterior knee pain in adolescents is generally recognised as a common but benign self-limiting condition. Although many operative procedures for its treatment have been proposed, there is little statistical evidence that they are more effective than expectant management. A group of 54 adolescent girls has been followed for two to eight years from presentation with anterior knee pain. Although some pain persisted in the majority, in many the symptoms declined in severity. This study provides a baseline for comparison with the results of operative intervention; it is suggested that surgical treatment is unproven and unnecessary


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_10 | Pages 77 - 77
1 May 2016
Comitini S Tigani D Leonetti D Amendola L Commessatti M
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Introduction. Acute poliomyelitis is a very rare disease in western countries, however the remnant of the pathology can be find among the adult patients. In poliomyelitis, sensation is normal and patients may suffer from painful etiologies. Total knee arthroplasty (TKA) with non-hinged or semi hinged prosthesis systems may be a good options to relief the pain in poliomyelitic patients, however the knee remains unstable. Using the hinged system implant may be the good option to resolve the late. Although the main concern in case of hinged implant usage is the mechanical stress which is directly transferred to the bone surface in contact with the implant. This may leads to implant mobilization and consequently failure. Methods and Materials. From 2004 to 2014, 14 TKA were performed in poliomyelitic patients with secondary knee pain. All patients were presented with extensor compartment hyposthenia and reduced antigravity function. In all patients a third generation rotating hinged knees (RHK) implant system (Zimmer, Warsaw, IN, USA) was applied. Bilateral TKA was performed in only one case. The mean age at the time of surgery was 56 years (ranged 48–77). Mean follow-up was 60 months (24–112). Results Due to post-operative infection, one patient underwent knee arthrodesis and excluded from the study. In one case, patellar fracture occurred 3 month following the surgery and treated non-surgically. Pain relief was observed in all patients following the surgery without any major complication. Mean objective score according to knee society knee scoring system was improved from 28 (16–51) preoperatively to 79 (72–88) postoperatively. Mean functional score was improved from 24 (5–35) preoperatively to 66 (50–70) postoperatively. At last follow up the mean range of motion was 90° (75°−100°). Following radiographic control at last follow-up all implants was stable without any sign of failure such as mobilization, radiolucency line or osteolysis. Conclusion. Providing stable knee implant system is the most important factor in addition to pain relief in case of poliomyelitic patients with knee pain. In our experience, third generation RHK supplied satisfactory clinical results in poliomyelitic patients supplying good implant stability without interfere with existing intrinsic stability of the lower limb. We believe that good results were achieved due to particular specification of RHK implant including mild 3° of hyperextension and weight distribution mode in which 95% transfer to polyethylene insert and only 5% to hinged compartment that help to restore the stability in such a particular patients also in case of late post-polio syndrome


The Journal of Bone & Joint Surgery British Volume
Vol. 71-B, Issue 2 | Pages 296 - 299
1 Mar 1989
Macdonald D Hutton J Kelly I

We assessed patellofemoral joint function by combining the measurement of maximal isometric extensor torque at the knee with clinical and radiological measurements in order to calculate the patellofemoral contact force. Eighteen volunteers established the normal ranges of results and the reliability of the system. Of the 39 patients with a variety of knee problems, 29 had anterior knee pain, and all had a subsequent arthroscopy. Patients with anterior knee pain and lesions in the patellar cartilage had significantly reduced isometric contact forces, but those with normal patellofemoral cartilage had normal contact forces. Our method may be useful in providing an objective assessment of anterior knee pain and a quantitative means of monitoring its treatment


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 321 - 321
1 Jul 2008
Patil S Kumar V Kamath V White L Dixon J Hui A
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Introduction: Poor proprioception and imbalance between quadriceps and hamstrings have been suggested as causes for anterior knee pain. The aim of our study was to compare the proprioception of patients with anterior knee pain to a normal population and to compare the activity of quadriceps and hamstrings using electromyography (EMG) in the 2 groups. Methods: Patients and controls between the ages 11–25 yrs were recruited into the study. The proprioception (stability index) of the patients and controls was tested using the Biodex stability system. This computerised system tests the ability of a person to balance his/her own body on a platform that moves in various directions. Surface EMG was recorded from the quadriceps and hamstrings during this test. EMG was also recorded as the patients and controls stepped onto a 20cm step. EMG activity was normalised to levels elicited during maximal isometric contractions. Results: 18 patients and 27 controls were recruited. We found no significant difference between the groups in the EMG intensity of vastus lateralis relative to biceps femoris, or vastus medialis relative to vastus lateralis, during the balance test or during the step up task (Mann Whitney U test all p> 0.05). We did not find any difference in the proprioceptive abilities of the two groups. Conclusion: We found no significant difference between the groups in the intensity of muscle contraction of the hamstrings relative to the quadriceps, i.e. no evidence for an imbalance in the patients. However the temporal relation between the two needs further investigation


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 103 - 103
1 Mar 2006
Bohnsack M Hurschler C Wilharm A Ruehmann O Stukenborg-Colsman C Wirth C
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Purpose: The study was designed to evaluate the biomechanical and neurohistological properties of the infrapatellar fat especially concerning its potential role in the anterior knee pain syndrome. Methods: Isokinetic knee extension from 120 of flexion to full extension was simulated on 10 human knee cadaver specimens (6 male, 4 female, average age at death 44 years). Joint kinematics was evaluated by ultrasound sensors (CMS 100TM, Zebris, Isny, Germany), and retro-patellar contact pressure was measured using a thin-film resistive ink pressure system (K-ScanTM 4000, Tekscan, Boston). The infrapatellar tissue pressure was analyzed using a closed sensor cell. The patellar contact pressure was measured before and after resection of the infrapatellar fat pad. The distribution of nerve fibres in the infrapatellar fat pad was assed immunohistologically in a second part of the study. Results: Infrapatellar tissue pressure significantly increased during knee extension < 20 and flexion > 100 ranging from 343 (223) mbar at O- to 60 (64) mbar at 60 of flexion. Total resection of the infrapatellar fat pad resulted in a significant decrease in tibial external rotation of 3° in full knee extension (p=0.011), combined with a significant medial translation of the patella between 29 and 69° knee flexion (p=0.017 to 0.028). Retropatellar contact pressure was significantly (p< 0.05) reduced at all flexion angles, at 120° knee flexion more than in full knee extension. Studying all the detectable nerves present in 50 fields (x200 objective) we found an average of 6.4 substance-P- (25%) of a total of 24.7 nerve fibres in the infrapatellar fat pad. There was a significantly (p< 0.01) higher number of substance-P-fibers (24.4 (28%) of 105.7) in the superficial synovial tissue. The number of S-100-fibers was significantly (p< 0.05) higher in the central and lateral part of the fat pad. Conclusions: Based on these results, we conclude that resection of the infrapatellar fat pad could potentially reduce clinical symptoms in the anterior knee pain syndrome, and that, contrary to commonly believed, the infrapatellar fat pad may have a biomechanical function and play a role in the anterior knee pain syndrome


The Journal of Bone & Joint Surgery British Volume
Vol. 74-B, Issue 5 | Pages 745 - 748
1 Sep 1992
Fern E Winson I Getty C

Postoperative anterior knee pain was evaluated in a consecutive series of 138 knees in 108 patients with rheumatoid arthritis treated by total knee replacement with Mark I Insall-Burstein prostheses. No knee had primary patellar resurfacing, and in the 119 knees followed up for a mean of 63.9 months, none had secondary resurfacing. Anterior knee pain was absent in 87 knees (73%), mild in 16 (13.5%) and moderate or severe in 16 (13.5%). The height of the patella above the prosthetic joint line was the only variable which was directly related to the incidence of anterior knee pain. The sensitivity and specificity of patellar height measurements for identifying patients with or without pain were derived. From these data, a selective policy of resurfacing the patella in those at risk was adopted. Choosing a patellar height of 15 mm or less, patellar resurfacing could be avoided in 80% of patients likely to have no pain, and the patella could be resurfaced in 65% of those likely to have anterior knee pain


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIX | Pages 80 - 80
1 Jul 2012
Wong F Przedlacka A Tan HB Allen P
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PURPOSES. Previous studies on patella-femoral morphology have suggested patella maltracking plays an important part in the aetiology but there had been no studies correlating maltracking with articular cartilage change. METHODS. We studied 147 consecutive patients (294 knees) aged between 10 and 63 presenting with anterior knee pain. All underwent MRI tracking scan of their knees as part of the routine investigations. We analysed the prevalence of maltracking with respect to gender, laterality and age groups, as well as patello-femoral articular cartilage changes. RESULTS. 52% of patients were found to have maltracking, of which 75% were bilateral. Furthermore, 66% of patients with maltracking had radiological evidence of patellar articular cartilage changes, corresponding to 61% of 294 knees examined. While majority of these occur at lateral facet, a proportion of medial facet changes (16%) is also seen. More significantly, while 25% of knees from patients with maltracking under the age of 20 are found to have changes on the patella cartilage, this increases to 93% by the age of 50 or above, with step-wise increment per decade of age (p<0.01). CONCLUSION. Our results demonstrate a strong correlation between anterior knee pain symptoms, patella maltracking and changes in patello-femoral joint cartilages of varying severity. This has implications on the management of these patients and would suggest early correction of maltracking is indicated to prevent deterioration in the patello-femoral joint


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_II | Pages 120 - 120
1 Feb 2003
Boyd KT Tippett RJ Moran CG
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To assess the prevalence of anterior knee pain more than 5 years after closed intramedullary nailing of the tibia and evaluate the long-term socioeconomic impact of this complication in terms of knee function and employment. A retrospective, cohort study of 298 consecutive tibial intramedullary nailings in 295 patients. Minimum follow-up was 5 years and patients were assessed using a questionnaire and the Lysholm knee score. 26 patients are known to have died, 22 patients, greater than 60 years at the tune of their injury, were excluded, Thus, 251 knees in 248 patients were available for review. The mean age at follow-up was 40. 8 years. The male to female ratio was SA:1 and mean follow-up was 7. 9 years. Anterior knee sensory disturbance was reported by 58% of patients. This interfered with activities of daily living (ADLs) in 29%, work in 25% and sport in 37%. Anterior knee pain was reported by 47% of patients. This interfered with ADLs in 37%, work in 36% and sport in 57%, Anterior knee pain was present all the time in 4%, often in 12%, sometimes in 27%, rarely in 21% and never in 37%, Pain on kneeling was rated on a visual analogue scale as mild in 54%, moderate in 34% and severe 12%. AKP improved with time in 73% patients and became worse in 4%. The Lysholm score rated 4 1 % knees as excellent, 19% as good, 26% as fair and 14% as poor. 86% of patients have been able to return to work, 9% are currently unemployed and 5% disabled. The presence of anterior knee pain was felt by the patient to prevent return to previous work in 10%. Anterior knee pain persists in 47% of patients after intramedullary nailing of the tibia- There is some decrease in symptoms with time and the majority of patients are able to return to work and activities of daily living. However, anterior knee pain causes significant disability in a small number and all patients should be warned of this problem prior to surgery


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 104 - 104
1 Mar 2006
Aravindan S Prem H Newman-Sanders A Mowbray
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Purpose of the study: To develop a new treatment algorithm for patients with chronic anterior knee pain based on kinematic patella tracking MR imaging. Methods and Results: Patients with anterior knee pain of more than one year duration and not responding to non-operative treatment, underwent kinematic MRI study. The provocative test was performed with the conventional MRI scanner and the patient extending the knee against resistance, the resistance provided by inflated beach ball. A retrospective analysis was done of first seventy patients, who had undergone this scanning technique. On the imaging films, four measurements were made. They were patella subluxation, tilt, cartilage thickness and the Tibial Tubercle Trochlear distance (TTD). Patellar subluxation was classified as mild, moderate and severe. We found that a Tibial Tubercle Trochlea distance of 18mm had a specifity of 100% and a sensitivity of 89% for severe maltracking. Conclusion: Kinematic MR Imaging is a useful investigation before considering operative treatment for patients with chronic anterior knee pain. Based on our study, we conclude that those patients with moderate lateral maltracking with a TTD< 18 mm should be offered lateral release and those with severe maltracking and TTD> 18mm should have a tibial tubercle transfer, in addition to lateral release


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 152 - 152
1 Apr 2005
Aravindan S Prem H Newman-Sanders A Mowbray M
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Purpose of the study: To develop a new treatment algorithm for patients with chronic anterior knee pain based on kinematic patella tracking MR imaging. Methods and Results: Patients with anterior knee pain of more than one year duration and not responding to non-operative treatment, underwent kinematic MRI study. The provocative test was performed with the conventional MRI scanner and the patient extending the knee against resistance, the resistance provided by inflated beach ball. A retrospective analysis was done of first seventy patients, who had undergone this scanning technique. On the imaging films, four measurements were made. They were patella subluxation, tilt, cartilage thickness and the Tibial Tubercle Trochlear distance (TTD). Patellar subluxation was classified as mild, moderate and severe. We found that a Tibial Tubercle Trochlea distance of 18mm had a specifity of 100% and a sensitivity of 89% for severe maltracking. Conclusion: Kinematic MR Imaging is a useful investigation before considering operative treatment for patients with chronic anterior knee pain. Based on our study, we conclude that those patients with moderate lateral maltracking with a TTD< 18 mm should be offered lateral release and those with severe maltracking and TTD> 18mm should have a tibial tubercle transfer, in addition to lateral release


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIV | Pages 8 - 8
1 Jul 2012
Sarraf K Abdul-Jabar H Wharton R Shah G Singer G
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Femoral component fracture is a rarely reported but devastating complication of total knee arthroplasty. It has occurred most frequently with Whiteside Ortholoc II replacements uncemented knee replacements. Presentation may be with acute pain, progressive pain or returning deformity. It occurs more commonly in the medial condyle of the femoral component. It is rarely seen in cemented replacements. All currently available literature describing fractures of condylar replacements, both cemented and uncemented. Predisposing factors include varus deformity either pre or post operatively. The mechanism of failure is thought to be failure of the infiltration of bone into the replacement. This is often due to polyethylene wear or metallosis causing abnormal tissue reaction with or without osteolysis. We present the case of a fractured Press Fit Condylar (PFC) cemented implant (DePuy, Johnson&Johnson, Raynham, Massachusettes, USA) affecting the medial condyle. To our knowledge this is only the third reported case of fracture in a PFC implant, and the first in a cemented PFC implant. Our patient was a 64 year old male who presented with unresolving knee pain post total knee arthroplasty, caused by fatigue fracture of the medial condyle of the femoral component. This was identified as loosening on plain radiographs and replaced with a revision prosthesis with a good post operative result. Given our aging population and with the increase of joint arthroplasty, this case sheds light on a potentially under recognised and increasingly important cause of knee pain following arthroplasty


The Journal of Bone & Joint Surgery British Volume
Vol. 85-B, Issue 5 | Pages 675 - 678
1 Jul 2003
Muoneke HE Khan AM Giannikas KA Hägglund E Dunningham TH

Out of a total of 623 patients who, over a ten-year period, underwent primary total knee replacement (TKR) without patellar resurfacing, 20 underwent secondary resurfacing for chronic anterior knee pain. They were evaluated pre- and postoperatively using the clinical and radiological American Knee Society score. The mean follow-up was 36.1 months (12 to 104). The mean knee score improved from 46.7 to 62.2 points and the mean functional score from 44.7 to 52.2 points. Only 44.4% of the patients, however, reported some improvement; the remainder reported no change or deterioration. The radiographic alignment of the TKR did not influence the outcome of secondary resurfacing of the patella. Complications were noted in six of the 20 patients including fracture and instability of the patella and loss of movement. Anterior knee pain after TKR remains difficult to manage. Secondary resurfacing of the patella is not advocated in all patients since it may increase patient dissatisfaction and hasten revision