An abnormal lateral position of the tibial tuberosity causes distal malalignment of the extensor mechanism of the knee and can lead to lateral tracking of the patella causing anterior knee pain or objective patellar instability, characterised by recurrent dislocation. Computer tomography is used for a precise pre-operative assessment of the tibial tubercle-trochlear groove distance. A distance of more than 15 mm is considered to be pathological and an indication for surgery in symptomatic patients.

In a prospective study we performed a subtle transfer of the tibial tuberosity according to the information gained from the pre-operative CT scan. This method was applied to two groups of patients, those with painful lateral tracking of the patella, and those with objective patellar instability. We evaluated the clinical results in 30 patients in each group. The outcome was documented at 3, 12 and 24 months using the Lysholm scale, the Kujala score, and a visual analogue pain score.

Post-operatively, all but one patient in the instability group who had a patellar dislocation requiring further surgery reported good improvement with no further subluxation or dislocation. All patients in both groups had a marked improvement in pain and functional score. Two patients sustained a tibial fracture six and seven weeks after surgery. One patient suffered a per-operative fracture of the tibial tubercle which later required further fixation.

If carefully performed, this type of transfer of the tibial tubercle appears to be a satisfactory technique for the treatment of patients with an increased tibial tubercle-trochlear groove distance and who present with symptoms related to lateral maltracking of the patella.

Traumatic atlanto-occipital dislocation in adults is usually fatal and survival without neurological deficit is rare. The surgical management of those who do survive is difficult and controversial. Most authorities recommend posterior occipitoaxial fusion, but this compromises cervical rotation. We describe a case in which a patient with a traumatic atlanto-occipital disruption but no neurological deficit was treated by atlanto-occipital fusion using a new technique consisting of cancellous bone autografting supported by an occipital plate linked by rods to lateral mass screws in the atlas. The technique is described in detail. At one year the neck was stable, radiological fusion had been achieved, and atlantoaxial rotation preserved.

The rationale behind this approach is discussed and the relevant literature reviewed. We recommend the technique for injuries of this type.

Introduction: Fibroblast growth factor receptor 3 (FGFR3) is a tyrosine kinase membrane-spanning protein whose function is to regulate chondrocyte proliferation, differentiation and matrix production during cartilage development. Several mutations in FGFR3 have now been documented to link to human diseases. A number of these mutations result in constitutive activation of the FGFR3, leading to proliferation and premature differentiation of chondrocytes. Depending on the mutation and the resultant level of FGFR3 activation, mild to severe skeletal dysplasias such as achondroplasia (ACH), hypochondroplasia (HCH), thanatophoric dysplasia type I (TDI) and type II (TDII), and severe achondroplasia with developmental delay and acanthosis nigrans (SADDAN) may result. It has been postulated that the signalling pathways downstream of FGFR3 may be responsible for activating transcription factors, leading to up-regulation of cell cycle inhibitors and causing abnormal suppression of chondrocyte cell proliferation. However, the precise signalling pathways involved in FGFR3 mutation have as yet to be elucidated. The aim of this study was to investigate and compare the differences in the downstream signalling pathways between FGFR3 mutants.

Methods and Results: Wild type FGFR3 has been cloned into expression vector pcDNA3 and the construct has been used to generate four different FGFR3 mutants using site-directed mutagenesis. The mutations which have been introduced and the types of dysplasia they correspond to were as follows: K380R (ACH), N540K (HCH) and K650E (TDII). A kinase dead form of the receptor, K504R has also been generated. Wild type and each of the four mutant FGFR3 proteins in pcDNA3 vector have been successfully transfected into 293T cells using the calcium phosphate method. Immunoprecipitation and Western Blot analysis of cell lysates revealed expression of wild type protein in three isoforms of size 135kDa (mature), 120kDa (intermediate) and 98kDa (immature). The mutant proteins all followed a similar pattern of expression with the exception of the TDII mutant that did not express the mature form of the FGFR3. Changes in MAPK, PLCã and STAT 1 signalling pathways in response to FGFs-1, 2, 9 and 18 in the 293-cells of wild type and mutant forms of FGFR3 are now under investigation, in an attempt to define which pathways are mostly responsible for the resultant abnormal phenotypes.

Discussion: Genomics studies have demonstrated that FGFR3 expression is significantly upregulated during the osteoblastic differentiation of mesenchymal stem cells (MSCs) under BMP-2 stimulation in vitro. Subsequent functional studies have demonstrated that a selective ligand for FGFR3, FGF9, is able to induce tyrosine kinase signalling, and the osteoblastic differentiation of MSCs in vitro. Further understanding the signalling mechanisms of FGFR3 activation in normal and mutant forms may lead to discover potential anabolic agents that are based on FGFR3-FGFs pathways.

There is increasing pressure to develop virtual reality surgical simulation that can be used in surgical training. However, little is known of the attitudes of the surgical community towards such simulation, and which aspects of simulation are most important.

A postal survey on attitudes to surgical simulation was sent to all New Zealand orthopaedic surgeons and advanced trainees. This comprised 44 questions in ten sections, using either a visual analogue scale (0 to 10) or free text box replies. Results were analysed for two sub-groups; surgeons qualified before 1990 and those qualified in or after 1990 or still in training.

Of 208 possible responses, 142 were received, a response rate of 68%. Only 4 respondents had tried a surgical based simulator. Earlier qualified surgeons were more likely to agree that simulation was an effective way to practice surgical procedures, median score 7.7 versus 5.6 (p=0.03). Both groups thought the most important task for simulation was practicing angulation/spatial orientation (median score 8.4/10), while a realistic view of the operation was the most important requirement (median score 9/10). Both groups were unconvinced that simulation would impact on their practice in the next five years, with this statement being scored lower by later qualified surgeons, median score 2.4 versus 4.1 (p=0.04).

Orthopaedic surgeons in New Zealand are supportive of surgical simulation but do not expect simulation to have an impact in the near future. Intriguingly, later qualified surgeons and trainees are more sceptical than their earlier qualified colleagues.

Introduction: This study examined the cohort of patients selectively screened over a 5 year period with ultrasonography according to our risk factors (positive Ortolani or Barlow manoeuvre, breech presentation, first degree affected relative and talipes equinovarus) for developmental hip dysplasia (DDH). The aims were to evaluate the success of those managed in a Pavlik harness and identify predictive factors for those that failed treatment.

Methods: 728 patients were selectively screened between 1999 and 2004. Of those, 128 patients (189 hips) were identified as having hip instability. Failure was defined as inability to achieve or maintain hip reduction in a Pavlik harness. A proforma was designed to document patients’ risk factors and ultrasound findings at time of initial dynamic ultrasound scan where the senior radiographer and treating consultant were present. Each hip was classified according to Graf type. Acetabular indices were recorded prior to discharge.

Results: All 128 patients with hip instability were managed in a Pavlik harness. This was abandoned for surgical treatment in 9 patients (10 hips) giving a failure rate of 5.3 %. All those successfully managed had an acetabular index of less than 30 degrees at follow up (6 – 48 months). 7 hips in the series were classified as Graf type IV, of these, 6 went on to fail management in a Pavlik harness. 67% of those that failed were also breech presentation compared to 22% of those managed successfully. There were no complications associated with management in a Pavlik harness.

Discussion: Our overall rate of selective screening is 14 per 1,000 with a subsequent treatment rate of 2.3 per 1,000, which is comparable with other centres. Our rate of failure for DDH in a Pavlik harness (5.3 %) is extremely encouraging. Graf type IV hips and breech presentation correlated with a high likelihood of treatment failure.

Aim: Assessing Polyethylene wear is very important in following up patients after Total hip replacement (THR) and Livermore method (using callipers) is routinely used by clinicians in calculating this wear. Our aim was to assess if ‘Imagika’, a new computer software programme can accurately assess polyethylene wear(PE-wear). We also compared the computer software with the Livermore method in calculating wear.

Method: We used 15 different THR X rays of patients who had an ABG total hip replacement done. X rays that were included for the calculations were taken at different time intervals following the operation. Wear was calculated on each X ray by 3 clinicians using both the methods, on 3 separate occasions. We compared the Livermore method and the computer software for consistency of measurements and also calculated the inter and intra observer variability for both.

Results: There was a statistically significant difference (at the 5% level) between the measurements taken by the Imagika software and the Livermore method. F(1,88) = 5.38, p< 0.05. There was a statistically significant difference in the inter-observer measurements using the Livermore method. F(2,42) = 4.18, p< 0.05, but there was no significant inter-observer variation using the Imagika computer software. There was no statistically significant difference (at the 5%level) in the intra-observer variability of both groups.

Conclusion: The Imagika computer software proved to be better than the Livermore method in calculating wear with regards to inter-observer bias. There was also a significant difference between measurements taken using both methods. We conclude that the computer software may be a more accurate tool in the assessment of PE-wear in the future.

The object of this study was to develop a method to assess the accuracy of an image-free total knee replacement navigation system in legs with normal or abnormal mechanical axes. A phantom leg was constructed with simulated hip and knee joints and provided a means to locate the centre of the ankle joint. Additional joints located at the midshaft of the tibia and femur allowed deformation in the flexion/extension, varus/valgus and rotational planes. Using a digital caliper unit to measure the coordinates precisely, a software program was developed to convert these local coordinates into a determination of actual leg alignment. At specific points in the procedure, information was compared between the digital caliper measurements and the image-free navigation system. Repeated serial measurements were undertaken. In the setting of normal alignment the mean error of the system was within 0.5°. In the setting of abnormal plane alignment in both the femur and the tibia, the error was within 1°. This is the first study designed to assess the accuracy of a clinically-validated navigation system. It demonstrates in vitro accuracy of the image-free navigation system in both normal and abnormal leg alignment settings.

Introduction: Patello-femoral complications are a major problem after total knee arthroplasty (TKA). Purpose of the present study was to analyze patello-femoral complications and function after two different posterior-stabilized TKA designs (Optetrak 913 vs IB-II).

Materials and Methods: This study was performed in two consecutive phases. In the first phase 1410 TKA’s performed by the senior author between 1994 and 1998 were considered for chart review. Within this period, the last 300 IB-II and the first 300 913 performed were analyzed for patello-femoral complication rate. In the second phase, of the 600 charts analyzed, two matched groups (50 patients each of IB-II and 913), were selected for a clinical (Knee Society score), functional (HSS Patellar score) and radiological assessment (AP, Lateral, Merchant, modified-wb Merchant views).

Results: A lateral retinacular release was performed in 30% for the IB-II and 16% for the 913 (p=0.02). The following patello-femoral complications were encountered (phase-1):

IB-II 913

Patellar clunk 3.5% 0.3%

Dislocation 0% 0.3%

Fracture 0% 0.3%

Loosening 0% 0%

Clinical results at follow-up (phase-2) did not show any significant difference between the two matched groups in terms of Knee and Function scores (p=0.7). Patellar score showed a higher rate of excellent and good results in the 913 group (88% vs 81%: p=.043). Anterior knee pain was only mild and activity related in 26% of the IB-II and 14% of the 913 (p=.025). In a multivariate regression analysis, radiographic patellar tilt, subluxation, and height, did not correlate with clinical outcomes, whilst bone-implant contact showed a trend towards a higher incidence of pain, particularly when associated with asymmetric patellar resection.

Discussion: At an intermediate follow-up, the Optetrak 913 prostheses showed fewer complications and an improved patello-femoral function compared to the IB-II prosthesis.

Introduction: Patello-femoral evaluation after total knee arthroplasty (TKA) is not addressed by most knee scoring systems. Patellar radiographic assessment after TKA is obtained with static, unloaded views that may not reproduce the in-vivo patello-femoral kinematics. The purpose of this study was to develop and validate new reliable and reproducible clinical and radiographic assessment tools for analysis of the patello-femoral joint in TKA.

Materials and Methods: The existing axial Merchant view was modified by positioning the standing patient in the semi-squatted position with the knees at 45°. Relationship between X-ray source, the angle of incidence on the joint, and the cassette position, were kept unchanged from the original view. The standing position and consequent muscle involvement were the only differences. The quality of the view was confirmed on a cadaveric knee model with multiple markers. Safety, reproducibility and clinical reliability were obtained in 100 posterior-stabilized TKA’s. These patients were assessed by a new Patella Scoring System (0–100 points). This system considers anterior knee pain, crepitus, stair performance and quadriceps strength. Radiographic abnormalities are calculated as deductions. Intra- and inter-observer variability were obtained comparing the results of two different investigators.

Results: The modified Merchant view showed significant patello-femoral tracking changes in 68% of patients. Twenty-one cases of bone-implant contact were observed when load was applied. Correlation between excellent-good clinical outcome and excellent patello-femoral performance was significantly higher for the Patellar Score compared to Knee Society Clinic or Function scores (p=.022, p=.014). Multivariate regression analysis of radiographic tilt, subluxation, and height, did not correlate with clinical outcomes, whilst bone-implant contact showed higher incidence of pain, particularly when associated with asymmetric patellar resection.

Conclusion: These new patello-femoral clinical and radiological assessment methods employed in the study represent additional valuable tools for the comprehensive evaluation of results in TKA.

Aim To assess whether prosthetic femoral stem centralisers have a detrimental effect on the maroporosity of the cement mantle, and if so, whether this is independent of their design and the rate of implantation.

Methods 30 identical moulded prosthetic femora were divided into 3 groups. Group 1; no centraliser (control), Group 2; centraliser A, Group 3 centraliser B. Using third generation cementation techniques and pressure monitoring, Charnley C-stems +/− the appropriate centraliser were implanted to a constant depth. Half in each group were implanted as rapidly as possible and the other half over 90 seconds. The stems were removed and the cement mantle then underwent a preliminary arthroscopic examination prior to being sectioned transversely at 3 constant levels. Each level was then photographed and digitally enlarged to a known scale to allow examination and determination of any cement voids (macropores) surface area.

Results There were no significant pressure fluctuations between the groups. Preliminary arthroscopic examination revealed that cement voids appeared more common when a centraliser was used. This difference was statistically confirmed (p=0.002) following sectioning of the specimens with cement voids found in 85% of femora when a centraliser was used and only 20% in the control group. Centraliser B performed worst with cement voids of a larger volume and more frequent occurrence (p=0.002). The macroporosity of the cement mantle was independent of the rate of implantation (p=0.39).

Conclusion The use of femoral stem centralisers is helpful in preventing malposition of the implant but results in increased macroporosity of the cement mantle. This may have implications regarding the longevity of an implant in terms of early loosening and therefore their design and use must always be carefully considered.

Introduction and Aims: CT is one of the most versatile and useful medical imaging modalities for computer assisted surgery (CAS) and monitoring bone remodelling. However, the high radiation dosage hinders its widespread use. We describe a method for generating smooth and accurate Finite Element (FE) meshes using CT data with reduced radiation exposure.

Method: We have performed serial CT assisted osteodensitometry measurement on seven patients who had a total hip replacement. FE models were generated automatically with cubic Hermite basis functions for both geometry and density. The meshes were fitted to the geometric and density data sets using least square’s fitting. Density was displayed over the surface of the elements using a colour spectrum. The effect of reducing radiation dosage was studied by generating five different types of FE meshes from each patient with different numbers of CT slices. The different mesh types were generated by varying the gap between slices.

Results: The mesh with the smallest number of CT slices used seven CT scans, with the gap between slices of 3cm on average while the mesh with the largest number of slices used 22 scans with the gap of 0.8cm. For the mesh with the largest number of CT slices, the average error after the geometric fitting was less than 0.5mm. The average error for the density fitting was 70.2 mg/ml. When expressed as the percentage to the overall density data range (0 ~ 1500 mg/ml), the average error was 4.7%. Meshes generated with a smaller number of CT slices had larger errors, and this increased as the number of slices used decreased. The error in geometry dropped dramatically (more than 50%) when more than 10 slices were used, whereas the error in density decreased approximately linearly as the number of slices increased. Overall, it was possible to generate realistic and smooth meshes with a geometrical error of less than 1.5mm and a density error less than 7% using 10 CT slices.

Conclusion: One strength of the current study is that we have used cubic Hermite elements, which requires much less information in generating FE meshes without sacrificing too much accuracy. Our study has shown that we can generate realistic and smooth meshes with about 10 CT slices of the proximal femur. This is important to enhance the power of CT in clinical applications.

We report the incidence and location of deep-vein thrombosis in 312 patients who had sustained high-energy, skeletal trauma. They were investigated using magnetic resonance venography and Duplex ultrasound.

Despite thromboprophylaxis, 36 (11.5%) developed venous thromboembolic disease with an incidence of 10% in those with non-pelvic trauma and 12.2% in the group with pelvic trauma. Of patients who developed deep-vein thrombosis, 13 of 27 in the pelvic group (48%) and only one of nine in the non-pelvic group (11%) had a definite pelvic deep-vein thrombosis. When compared with magnetic resonance venography, ultrasound had a false-negative rate of 77% in diagnosing pelvic deep-vein thrombosis. Its value in the pelvis was limited, although it was more accurate than magnetic resonance venography in diagnosing clots in the lower limbs. Additional screening may be needed to detect pelvic deep-vein thrombosis in patients with pelvic or acetabular fractures.

Aim: To identify the local and systemic morbidity of simultaneous sequential bilateral total knee arthroplasty in a large patient population and to undertake a comparative statistical analysis with a group of matched patients who underwent staged bilateral total knee replacement during the same period.

Methods: Theatre records at two regional district general hospitals were scrutinised to identify all patients who had undergone simultaneous sequential and staged bilateral total knee arthroplasty over a three year period. Patient case notes and hospital charts were retrospectively reviewed to obtain several outcome measures to allow subsequent risk factor assessment.

Results: 134 patients with 268 primary knee arthroplasties undergoing a simultaneous procedure were identified. The average age was 70 with a minimum follow up of 12 months. The study results revealed 1.5% mortality, 5.2% local complication and 14.9% systemic complication rates and this increased with age. During the same period 34 patients (68 knees) who had undergone staged procedures at least 3 months apart were also identified. Statistically significant findings between both groups included the reduced length of hospital stay, a 3-fold increase in the requirement for banked blood (particularly when either suction drainage or low molecular weight heparin thromboprophylaxis was used) and a higher degree of intra operative instability in those undergoing simultaneous bilateral total knee replacement.

Conclusions: Patients can continue to enjoy the benefits of simultaneous bilateral knee arthroplasty, however, extreme caution must be taken in selection of patients over 75 years, high dependency facilities must be available and an acceptable alternative to banked blood transfusion needs to be used.

Bone autograft contains living cells that participate in the healing process. Fragmentation and heat production during cutting will kill cells. We have investigated how excessive graft fragmentation and heating can be avoided.

Two prototype cutters were fabricated. Each had a single cutting edge at the front end of a 12 mm diameter collection barrel. The principal difference between the cutters was the rake angle (at the cutting edge): 23° on cutter #1 and 45° on cutter #2.

Thrust load, feed-rate, and torque were measured using an instrumented drill press. A total of 58 tests on specimens of fresh bovine cancellous bone (distal femur, ex-abattoir) and medium density polyurethane foam (Sawbones, WA. USA) (density 252 kg/m³) were conducted: twenty-four at 100 rpm and thirty-four at 200 rpm.

Small flake-like fragmented bone chips were encountered at low thrust loads. As thrust load was increased the chips became thicker. The average cutting energy for bone was 43.7 Nm (s.d. 48.2 Nm) for cutter 1 and 37 Nm (s.d. 27 Nm) for cutter 2. The average cutting energy for the foam was 13.9 Nm (s.d. 6.0 Nm) for cutter 1 and 8.1 Nm (s.d. 3.0 Nm) for cutter 2. Polyurethane results showed a similar trend.

A higher rake angle on a bone graft tool is associated with a lower cutting energy. In turn, a lower cutting energy will generate a lower temperature in the graft, a result that is beneficial for cell survival. Graft tool design can also influence bone chip size. These experimental results are being used for the development of cell-friendly tooling.

Periprosthetic bone density (BD) changes can be tracked using computed-tomography (CT) assisted osteodensitometry. Patient-specific computer-generated models allow for good visualisation of density changes in bone. We describe techniques for generating smooth and realistic finite element (FE) models that contain both BD and geometry from quantitative CT data using cubic Hermite elements.

FE models were created for three patients who had a total hip replacement. CT-scans were performed at 10 days, one year, and 3 years after the operation and calibrated using a synthetic hydroxyapatite phantom. FE models of the proximal femur were automatically generated from the CT data. Each model had on average 300 tri-cubic Hermite elements. Models were least squares fitted to the entire dataset. BD data was also sampled and fitted using the same cubic interpolation functions. Density was displayed using a colour spectrum.

Realistic patient-specific FE models were obtained. Density and changes in BD were easy to identify. The error in the geometric fitting (RMS distance between data points and the model surface) was generally less then 0.5 mm. The average error for the density fitting (RMS difference between each density data point and the interpolation function value at the same point) was 61.64 mg/ml or 3.08%.

CT osteodensitometry’s potential use as a clinical tool for monitoring changes to BD can be significantly enhanced when used in conjunction with realistic patient-specific finite element (FE) models. Realistic models can be generated with an economic use of scan data, thus keeping radiation dosage down.

Introduction: Previous in vivo kinematic studies have assessed total knee arthroplasty (TKA) motion under weight-bearing conditions. This in vivo study analyzed and compared posterior cruciate retaining (PCR) and posterior stabilized (PS) kinematics under passive and weight-bearing conditions in subjects implanted with both a PCR and PS TKA.

Methods: Eighteen subjects were implanted with a PCR and a PS TKA, by a single surgeon using a similar surgical technique. Both implant designs had similar condylar geometry. Femorotibial contact positions for all 18 subjects (PCR and PS), implanted by a single surgeon, were analyzed using video fluoroscopy. Each subject,while under fluoroscopic surveillance, performed a weight-bearing deep knee bend and a passive, nonweight-bearing flexion. Video images were downloaded to a workstation computer and analyzed at varying degrees of knee flexion. Femorotibial contact paths for the medial and lateral condyles, axial rotation and femoral condylar lift-off were then determined using a computer automated model-fitting technique. Femorotibial contact anterior to the tibial midline in the sagittal plane was denoted as positive and contact posterior was denoted as negative.

Results: Under passive and weight-bearing conditions, the PCR TKA experienced more paradoxical anterior translation than the PS TKA. Under passive, non weight-bearing conditions, the PS TKA, on average, experienced 3.5 mm of posterior femoral rollback, compared to only 0.6 mm for the PCR TKA. Under weight-bearing conditions, the PS TKA experienced only 0.6 mm of posterior femoral rollback, compared to 0.9 mm for the PCR TKA. The maximum anterior slide was 10.0 mm for the PCR TKA and only 2.7 mm for the PS TKA. There was greater variability in both the PCR and PS anteroposterior data. Subjects having a PCR TKA experienced more normal axial rotation patterns. Sixteen of 18 PCR TKA experienced a normal axial rotation pattern under weight-bearing conditions, while only 9/18 PS TKA experienced a normal pattern. Nonweight-bearing, passive axial rotation patterns were more abnormal for both groups than the weight-bearing patterns. The greatest difference between passive and weight-bearing conditions occurred in the condylar lift-off data. Under passive conditions, both TKA groups experienced significantly greater magnitude and incidence of condylar lift-off. The maximum amount of condylar lift-off under passive conditions was 5.0 mm for the PCR TKA and 6.4 mm for the PS TKA.

Discussion: This is the first in vivo kinematic study to assess a comparison between PCR and PS TKA implanted by the same surgeon in the same patient. Subjects in this study experienced more abnormal kinematic patterns, especially condylar lift-off, when tested under passive, nonweight-bearing conditions. Subjects having a PS TKA experienced less variability in their kinematic data, but PCR TKA, on average, experienced more normal axial rotation and less condylar lift-off.

Introduction Comminuted intra-articular fractures of the distal radius are severe injuries where the outcome depends on accurate anatomical reduction and reconstitution of the articular surface, and early mobilisation. This prospective outcome study aims to assess the anatomical and functional outcome of internal fixation of these complex fractures using a fragment specific fixation system.

Methods Fifty consecutive comminuted intra-articular distal radius fractures presenting at our hospital were treated by the one surgeon (MP). Inclusion criteria were age under 80 and AO classification C-3. Various combinations of wires, buttress pins/clips and plates were utilized according to each fracture configuration. No post-op splintage was used. All patients commenced hand therapy from day one post-op. Patients were reviewed at two weekly intervals till fracture union and monthly thereafter. All patients were independently assessed by a hand therapist for range of motion and grip strength. Patient function was assessed using the DASH (Disabilities of the Arm, Shoulder and Hand) and the PRWE scores. Thirteen males and 37 female with an average age of 53.8 (29 to 72) were treated with the TriMed between February 2002 and February 2003. Average follow-up was seven months (3 to 14).

Results All fractures had healed at the six week review, with mean palmar tilt of 12°, radial tilt of 19° and radioulnar variance of 5 mm, with articular step less than 1 mm. The mean DASH score was 19 (SD 9) and mean PRWE score was 19 (SD 11). Average range-of-motion was 65 (SD 17) dorsi-flexion, 55 (SD 19) palmar-flexion, 73 pronation and 67 supination. Grip strength recovered to 85% on average when compared to the opposite hand. There were no deep or superficial wound infections. Three patients had difficulty regaining early hand function, with difficulty complying with physiotherapy. One had borderline mental retardation. Two displayed symptoms of RDS, one responding to medication, and one requiring guanethidine arm block.

Conclusions Intra-articular distal radius fractures can be reliably and anatomically reduced and stabilized using fragment-specific fixation. Fixation of markedly comminuted fractures is secure enough to allow immediate motion. Clinical and radiographic results are excellent, and patient satisfaction is high. Patient compliance with hand therapy is critical for a good functional result.

Introduction: Previously, in vivo kinematic studies have determined the in vivo kinematics of the femur relative to the metal base-plate. These kinematic studies have reported posterior femoral rollback in posterior stabilized (PS) TKA designs, but the actual time of cam/post engagement was not determined. The objective of this present study was to determine, under in vivo conditions, the time of cam/post engagement and the kinematics of the femur relative to the polyethylene insert.

Methods: Femorotibial contact positions for twenty subjects having a PS TKA, implanted by two single surgeons, were analyzed using video fluoroscopy. Ten subjects were implanted with a PS TKA that is designed for early cam/post engagement (PSE) and ten subjects with a PS TKA designed for later cam/post engagement (PSL). Each subject, while under fluoroscopic surveillance, performed a weight-bearing deep knee bend to maximum flexion. Video images were downloaded to a workstation computer and analyzed at ten-degree increments of knee flexion. Femorotibial contact paths for the medial and lateral condyles, axial rotation and condylar lift-off were then determined using a computer automated model-fitting technique.

Results: Subjects implanted with the PSE TKA experienced, on average, the cam engaging the post at 48° (10 to 80°). Subjects having the PSL TKA experienced more consistent results and did experience engagement in deep flexion (Average 75°). Subjects having the PSE TKA experienced, on average, −5.5 mm (1.5 to −9.3) of posterior femoral rollback (PFR), while subjects having the PSL TKA experienced only −2.6 mm (8.5 to −9.0) of PFR. Subjects having the PSE TKA experienced more normal axial rotation patterns. Nine subjects having the PSE TKA experienced condylar lift-off (maximum = 1.9 mm), while only 4/10 having the PSL TKA experienced condylar lift-off (maximum = 2.7 mm).

Discussion: This is the first study to determine the in vivo contact position of the cam/post mechanism. Subjects having a PSE TKA experienced earlier cam/post engagement than subjects having the PSL TKA. Some subjects did not experience any cam/post engagement throughout knee flexion. Subjects having the PSE TKA experienced more PFR and better axial rotation patterns, but subjects having a PSL TKA experienced lesser incidence of condylar lift-off. Results from this study suggest that there may be an advantage to early cam/post engagement, which leads to more normal axial rotation patterns caused by the medial condyle moving in the anterior direction as the lateral condyle rolls in the posterior direction.

Introduction: Previous in vivo kinematic analyses of the hip joint have determined that femoral head separation from the medial aspect of the acetabular component occurs in metal-on-polyethylene THA. The present study analyzes subjects having either an alumina-on-alumina (AOA),alumina-on-polyethylene (AOP),metal-on-metal (MOM) or metal-on-polyethylene (MOP) THA during gait to determine if the incidence of hip joint separation varies based on articular surface material.

Methods: Forty subjects were analyzed in vivo using video fluoroscopy. Ten subjects had a AOA THA, ten an AOP THA, ten a MOM THA, and ten having a MOP THA. All THA subjects were implanted by two surgeons and were judged clinically successful (Harris hip scores > 90.0). Each subject performed normal gait on a treadmill and an abduction/adduction leg lift maneuver while under fluoroscopic surveillance. The two-dimensional (2D) fluoroscopic videos were converted into 3D using a computer automated model-fitting technique. Each implant was analyzed at varying flexion angles to assess the incidence of hip joint separation.

Results: During gait and the abduction/adduction leg lift, no separation was observed in subjects having an AOA THA or in subjects having a MOM THA. Similar to our previous studies pertaining to subjects having a THA with a polyethylene acetabular insert, all ten subjects having a MOP THA and 6/10 subjects having an AOP THA experienced hip joint separation. The maximum amount of separation was 7.4 mm for a subject having an AOP THA and 3.1 mm for a subject having a MOP THA.

Discussion: This study shows femoral head separation from the medial aspect of the acetabular component can occur in the presence of a polyethylene liner. The femoral head often remains in contact with the liner, hinging superolaterally. Potential detrimental effects resulting from hip joint separation include premature polyethylene wear, component loosening (secondary to impulse loading conditions) and hip instability. Wear may be enhanced due to creation of multidirectional wear vectors or excessive loads due to eccentric femoral head pivoting. The absence of separation observed in AOA and MOM THA designs may be related to increased wettability of these materials and tighter radial tolerances resulting in a cohesive lubrication film. This data may be of value in hip simulation studies to better duplicate wear patterns observed in retrieval analyses and assist in the understanding of the lubrication regime and wear rates in AOA and MOM designs, allowing for the synthesis of prosthetic components that minimize wear and optimize kinematics.