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Bone & Joint Open
Vol. 5, Issue 5 | Pages 401 - 410
20 May 2024
Bayoumi T Burger JA van der List JP Sierevelt IN Spekenbrink-Spooren A Pearle AD Kerkhoffs GMMJ Zuiderbaan HA

Aims. The primary objective of this registry-based study was to compare patient-reported outcomes of cementless and cemented medial unicompartmental knee arthroplasty (UKA) during the first postoperative year. The secondary objective was to assess one- and three-year implant survival of both fixation techniques. Methods. We analyzed 10,862 cementless and 7,917 cemented UKA cases enrolled in the Dutch Arthroplasty Registry, operated between 2017 and 2021. Pre- to postoperative change in outcomes at six and 12 months’ follow-up were compared using mixed model analyses. Kaplan-Meier and Cox regression models were applied to quantify differences in implant survival. Adjustments were made for patient-specific variables and annual hospital volume. Results. Change from baseline in the Oxford Knee Score (OKS) and activity-related pain was comparable between groups. Adjustment for covariates demonstrated a minimally greater decrease in rest-related pain in the cemented group (β = -0.09 (95% confidence interval (CI) -0.16 to -0.01)). Cementless fixation was associated with a higher probability of achieving an excellent OKS outcome (> 41 points) (adjusted odds ratio 1.2 (95% CI 1.1 to 1.3)). The likelihood of one-year implant survival was greater for cemented implants (adjusted hazard ratio (HR) 1.35 (95% CI 1.01 to 1.71)), with higher revision rates for periprosthetic fractures of cementless implants. During two to three years’ follow-up, the likelihood of implant survival was non-significantly greater for cementless UKA (adjusted HR 0.64 (95% CI 0.40 to 1.04)), primarily due to increased revision rates for tibial loosening of cemented implants. Conclusion. Cementless and cemented medial UKA led to comparable improvement in physical function and pain reduction during the initial postoperative year, albeit with a greater likelihood of achieving excellent OKS outcomes after cementless UKA. Anticipated differences in early physical function and pain should not be a decisive factor in the choice of fixation technique. However, surgeons should consider the differences in short- and long-term implant survival when deciding which implant to use. Cite this article: Bone Jt Open 2024;5(5):401–410


Bone & Joint Open
Vol. 4, Issue 3 | Pages 210 - 218
28 Mar 2023
Searle HKC Rahman A Desai AP Mellon SJ Murray DW

Aims. To assess the incidence of radiological lateral osteoarthritis (OA) at 15 years after medial unicompartmental knee arthroplasty (UKA) and assess the relationship of lateral OA with symptoms and patient characteristics. Methods. Cemented Phase 3 medial Oxford UKA implanted by two surgeons since 1998 for the recommended indications were prospectively followed. A 15-year cumulative revision rate for lateral OA of 5% for this series was previously reported. A total of 163 unrevised knees with 15-year (SD 1) anterior-posterior knee radiographs were studied. Lateral joint space width (JSW. L. ) was measured and severity of lateral OA was classified as: nil/mild, moderate, and severe. Preoperative and 15-year Oxford Knee Scores (OKS) and American Knee Society Scores were determined. The effect of age, sex, BMI, and intraoperative findings was analyzed. Statistical analysis included one-way analysis of variance and Kruskal-Wallis H test, with significance set at 5%. Results. The mean age was 80.6 years (SD 8.3), with 84 females and 79 males. The mean JSW. L. was 5.6 mm (SD 1.4), and was not significantly related to age, sex, or intraoperative findings. Those with BMI > 40 kg/m. 2. had a smaller JSW. L. than those with a ‘normal’ BMI (p = 0.039). The incidence of severe and moderate lateral OA were both 4.9%. Overall, 2/142 (1.4%) of those with nil/mild lateral OA, 1/8 (13%) with moderate, and 2/8 (25%) with severe subsequently had a revision. Those with severe (mean OKS 35.6 (SD 9.3)) and moderate OA (mean OKS 35.8 (SD 10.5)) tended to have worse outcome scores than those with nil/mild (mean OKS 39.5 (SD 9.2)) but the difference was only significant for OKS-Function (p = 0.044). Conclusion. This study showed that the rate of having severe or moderate radiological lateral OA at 15 years after medial UKA was low (both 4.9%). Although patients with severe or moderate lateral OA had a lower OKS than those with nil/mild OA, their mean scores (OKS 36) would be classified as good. Cite this article: Bone Jt Open 2023;4(3):210–218


Bone & Joint Open
Vol. 4, Issue 6 | Pages 457 - 462
26 Jun 2023
Bredgaard Jensen C Gromov K Petersen PB Jørgensen CC Kehlet H Troelsen A

Aims. Medial unicompartmental knee arthroplasty (mUKA) is an advised treatment for anteromedial knee osteoarthritis. While long-term survival after mUKA is well described, reported incidences of short-term surgical complications vary and the effect of surgical usage on complications is less established. We aimed to describe the overall occurrence and treatment of surgical complications within 90 days of mUKA, as well as occurrence in high-usage centres compared to low-usage centres. Methods. mUKAs performed in eight fast-track centres from February 2010 to June 2018 were included from the Lundbeck Foundation Centre for Fast-track Hip and Knee Replacement Database. All readmissions within 90 days of surgery underwent chart review and readmissions related to the surgical wound or the prosthesis were recorded. Centres were categorized as high-usage centres when using mUKA in ≥ 20% of annual knee arthroplasties. The occurrence of complications between high- and low-usage centres were compared using Fisher’s exact test. Results. We included 3,757 mUKAs: 2,377 mUKAs from high-usage centres and 1,380 mUKAs from low-usage centres. Surgical complications within 90 days occurred in 69 cases (1.8%), 45 (1.9%) in high-usage centres and 24 (1.7%) in low-usage centres (odds ratio (OR) 1.1 (95% confidence interval (CI) 0.65 to 1.8)). The most frequent complications were periprosthetic joint infections (PJIs) (n = 18; 0.48%), wound-related issues (n = 14; 0.37%), and periprosthetic fractures (n = 13; 0.35%). Bearing dislocations (n = 7; 0.19%) occurred primarily in procedures from high-usage centres. In high-usage centres, seven periprosthetic fractures (0.29%) occurred compared to six (0.43%) in low-usage centres (OR 0.68 (95% CI 0.20 to 2.0)). In high-usage centres, nine PJIs (0.38%) occurred compared to nine (0.65%) in low-usage centres (OR 0.58 (95% CI 0.22 to 1.6)). Conclusion. Surgical complications are rare after fast-track mUKA surgery and with no difference in overall occurrence of surgical complications between high- and low-usage centres, although the risk of some specific surgical complications may favour high-usage centres. Cite this article: Bone Jt Open 2023;4(6):457–462


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_13 | Pages 21 - 21
7 Aug 2023
Petsiou D Nicholls K Wilcocks K Matthews A Vachtsevanos L
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Abstract. Introduction. In patients with bilateral unicompartmental knee osteoarthritis, simultaneous bilateral surgery is cost effective, with both patient-specific and wider socioeconomic benefits. There are concerns however regarding higher complication rates with bilateral knee surgery. This study compares simultaneous bilateral unicompartmental knee arthroplasty (UKA), to single side UKA in terms of complications and outcomes. Methodology. This is a retrospective case-control study of single side medial UKA patients (controls) and simultaneous bilateral medial UKA patients (cases). All patients underwent surgery between 2018 and 2022 by a single surgeon. The two cohorts were compared for perioperative blood loss (PBL), length of stay (LOS), complications (infections, blood clots, wound problems), Oxford Knee Score improvement (OKS) and revision surgery, with a follow-up period of up to 5 years. Results. 64 patients were followed up comprising 55 controls and 9 cases. Average length of stay for controls was 1.55 days and 2.22 days for cases (p=0.03). Average haemoglobin drop was 7.5g/l in controls and 12.8g/l in cases (p=0.04). The OKS improvement was comparable in both groups (p=0.95) with no complications and no revision surgery in either group. Conclusion. The statistically significant differences in PBL and LOS were not clinically relevant. There were no blood transfusions and postoperative haemoglobin was within normal range in more than 60% of cases. Simultaneous bilateral unicompartmental knee arthroplasty is a financially favourable and safe option for patients with bilateral knee medial unicompartmental osteoarthritis


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_6 | Pages 35 - 35
1 Jul 2020
Tsukamoto I Yamagishi K Nakagawa K Inoue S Akagi M
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We proposed the substitute anteroposterior (sAP) line of the tibia for medial unicompartmental knee arthroplasty (UKA), which connects the medial border of the patellar tendon at the articular surface level and the medial intercondylar tubercle of the tibia. However, it has not been shown that referencing this line improves the rotational alignment of the components. Therefore, in this study, we investigated whether the tibial component could be implanted perpendicular to the SEA by referencing the sAP line and whether referencing the sAP line could reduce the rotational mismatch between the femoral and the tibial components. Postoperative computed tomography datasets from 60 lower limbs in 57 Japanese patients with medial UKA were used. Among these, 30 knees were operated using the sAP line for AP reference and other 30 knees using the medial intercondylar ridge (MIR) line. First, the angle between the AP orientation of the tibial component and the surgical epicondylar axis (SEA) was measured. Then, the rotational mismatch angle between the components was measured. The tibial and femoral components placed referencing the sAP line were externally rotated 90.7°±3.2° and 91°±7.7° relative to the SEA, respectively, those referencing the MIR line were 94.9°±8.5° and 91.2°±7.7°, respectively. When referencing the sAP line, the orientation of the component was more perpendicular to the SEA (Student t-test, unpaired, P = .016) and rotational variability of the tibial component was significantly smaller (F test, P < 0 .0001). The rotational mismatch angle when referencing the sAP line and the MIR line was 0.3°±8.3°and −3.8°±6.7°, respectively. Referencing the sAP line significantly reduced the rotational mismatch between the components (Student t-test, unpaired, P = .045). Referencing the sAP line in the medial UKA may be useful to determine the AP orientation of the tibial component


Bone & Joint Research
Vol. 9, Issue 9 | Pages 593 - 600
1 Sep 2020
Lee J Koh Y Kim PS Kang KW Kwak YH Kang K

Aims. Unicompartmental knee arthroplasty (UKA) has become a popular method of treating knee localized osteoarthritis (OA). Additionally, the posterior cruciate ligament (PCL) is essential to maintaining the physiological kinematics and functions of the knee joint. Considering these factors, the purpose of this study was to investigate the biomechanical effects on PCL-deficient knees in medial UKA. Methods. Computational simulations of five subject-specific models were performed for intact and PCL-deficient UKA with tibial slopes. Anteroposterior (AP) kinematics and contact stresses of the patellofemoral (PF) joint and the articular cartilage were evaluated under the deep-knee-bend condition. Results. As compared to intact UKA, there was no significant difference in AP translation in PCL-deficient UKA with a low flexion angle, but AP translation significantly increased in the PCL-deficient UKA with high flexion angles. Additionally, the increased AP translation became decreased as the posterior tibial slope increased. The contact stress in the PF joint and the articular cartilage significantly increased in the PCL-deficient UKA, as compared to the intact UKA. Additionally, the increased posterior tibial slope resulted in a significant decrease in the contact stress on PF joint but significantly increased the contact stresses on the articular cartilage. Conclusion. Our results showed that the posterior stability for low flexion activities in PCL-deficient UKA remained unaffected; however, the posterior stability for high flexion activities was affected. This indicates that a functional PCL is required to ensure normal stability in UKA. Additionally, posterior stability and PF joint may reduce the overall risk of progressive OA by increasing the posterior tibial slope. However, the excessive posterior tibial slope must be avoided. Cite this article: Bone Joint Res 2020;9(9):593–600


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_13 | Pages 127 - 127
1 Nov 2021
Batailler C Lording T Naaim A Servien E Cheze L Lustig S
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Introduction and Objective. In recent studies, robotic-assisted surgical techniques for unicompartmental knee arthroplasty (UKA) have demonstrated superior implant positioning and limb alignment compared to a conventional technique. However, the impact of the robotic-assisted technique on clinical and functional outcomes is less clear. The aim of this study was to compare the gait parameters of UKA performed with conventional and image-free robotic-assisted techniques. Materials and Methods. This prospective, single center study included 66 medial UKA, randomized to a robotic-assisted (n=33) or conventional technique (n=33). Gait analysis was performed on a treadmill at 6 months to identify changes in gait characteristics (walking speed, each degree-of-freedom: flexion–extension, abduction–adduction, internal-external rotation and anterior-posterior displacement). Clinical results were assessed at 6 months using the IKS score and the Forgotten Joint Score. Implants position was assessed on post-operative radiographs. Results. Post-operatively, the whole gait cycle was not significantly different between groups. In both groups there was a significant improvement in varus deformity between the pre- and post-operative gait cycle. There was no significant difference between the two groups in clinical scores, implant position, revision and complication rates. Conclusions. No difference of gait parameters could be identified between medial UKA performed with image-free robotic-assisted technique or with conventional technique


The Bone & Joint Journal
Vol. 104-B, Issue 5 | Pages 541 - 548
1 May 2022
Zhang J Ng N Scott CEH Blyth MJG Haddad FS Macpherson GJ Patton JT Clement ND

Aims. This systematic review aims to compare the precision of component positioning, patient-reported outcome measures (PROMs), complications, survivorship, cost-effectiveness, and learning curves of MAKO robotic arm-assisted unicompartmental knee arthroplasty (RAUKA) with manual medial unicompartmental knee arthroplasty (mUKA). Methods. Searches of PubMed, MEDLINE, and Google Scholar were performed in November 2021 according to the Preferred Reporting Items for Systematic Review and Meta-­Analysis statement. Search terms included “robotic”, “unicompartmental”, “knee”, and “arthroplasty”. Published clinical research articles reporting the learning curves and cost-effectiveness of MAKO RAUKA, and those comparing the component precision, functional outcomes, survivorship, or complications with mUKA, were included for analysis. Results. A total of 179 articles were identified from initial screening, of which 14 articles satisfied the inclusion criteria and were included for analysis. The papers analyzed include one on learning curve, five on implant positioning, six on functional outcomes, five on complications, six on survivorship, and three on cost. The learning curve was six cases for operating time and zero for precision. There was consistent evidence of more precise implant positioning with MAKO RAUKA. Meta-analysis demonstrated lower overall complication rates associated with MAKO RAUKA (OR 2.18 (95% confidence interval (CI) 1.06 to 4.49); p = 0.040) but no difference in re-intervention, infection, Knee Society Score (KSS; mean difference 1.64 (95% CI -3.00 to 6.27); p = 0.490), or Western Ontario and McMaster Universities Arthritis Index (WOMAC) score (mean difference -0.58 (95% CI -3.55 to 2.38); p = 0.700). MAKO RAUKA was shown to be a cost-effective procedure, but this was directly related to volume. Conclusion. MAKO RAUKA was associated with improved precision of component positioning but was not associated with improved PROMs using the KSS and WOMAC scores. Future longer-term studies should report functional outcomes, potentially using scores with minimal ceiling effects and survival to assess whether the improved precision of MAKO RAUKA results in better outcomes. Cite this article: Bone Joint J 2022;104-B(5):541–548


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_1 | Pages 104 - 104
1 Feb 2020
Zarei M Hamlin B Urish K Anderst W
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INTRODUCTION. Controversy exists regarding the ability of unicompartmental knee arthroplasty (UKA) to restore native knee kinematics, with some studies suggesting native kinematics are restored in most or all patients after UKA. 1–3. , while others indicate UKA fails to restore native knee kinematics. 4,5. Previous analysis of UKA articular contact kinematics focused on the replaced compartment. 2,5. , neglecting to assess the effects of the arthroplasty on the contralateral compartment which may provide insight to future pathology such as accelerated degeneration due to overload. 6. or a change in the location of cartilage contact. 7. The purpose of this study was to assess the ability of medial UKA to restore native knee kinematics, contact patterns, and lateral compartment dynamic joint space. We hypothesized that medial UKA restores knee kinematics, compartmental contact patterns, and lateral compartment dynamic joint space. METHODS. Six patients who received fixed-bearing medial UKA consented to participate in this IRB-approved study. All patients (4 M, 2 F; average age 62 ± 6 years) completed pre-surgical (3 weeks before) and post-surgical (7±2 months) testing. Synchronized biplane radiographs were collected at 100 images per second during three repetitions of a chair rise movement (Figure 1). Motion of the femur, tibia, and implants were tracked using an automated volumetric model-based tracking process that matches subject-specific 3D models of the bones and prostheses to the biplane radiographs with sub-millimeter accuracy. 8. Anatomic coordinate systems were created within the femur and tibia. 9. and used to calculate tibiofemoral kinematics. 10. Additional outcome measures included the center of contact in the medial and lateral compartments, and the lateral compartment dynamic joint space (i.e. the distance between subchondral bone surfaces). 11. The results of the three movement trials were averaged for each knee in each test session. All outcome measures were interpolated at 5° increments of knee extension (Figure 2). The average differences between knees at corresponding flexion angles were analyzed using paired t-tests with significance set at p < 0.05. RESULTS. The UKA knee was in 5.3° more varus than the contralateral knee prior to surgery (p=0.005). After surgery, the UKA knee was in 4.9° more valgus than before surgery (p=0.005). The UKA knee was 4.3° more externally rotated than the contralateral knee post-surgery (p=0.05) (Table 1). No significant differences were observed between knees or pre- to post-surgery in lateral compartment dynamic joint space or the center of contact in the medial and lateral tibia compartments (Table 1). DISCUSSION. These results suggest that medial UKA can restore native knee varus without significantly altering lateral compartment joint space or contact location during the chair rise movement. For any figures or tables, please contact the authors directly


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_30 | Pages 33 - 33
1 Aug 2013
Bell S Mullen M Leach W Rooney B
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We report the short term follow up of nineteen consecutive PFC sigma unicompartmental knee replacements carried out in our institution with minimum one year follow up. The PFC Sigma medial unicompartmental knee replacement is a fixed bearing, cemented unicompartmenal knee replacement. There are currently no published reports of follow up for the PFC Sigma medial unicompartmental knee replacement. Nineteen patients (nineteen knees) underwent PFC sigma medial unicompartmental knee arthroplasty. The pre-operative diagnosis was osteoarthritis in eighteen patients and osteonecrosis in one patient. There were ten males and nine females with a mean age of sixty four years. All patients had clinical and radiological review at one year. All operations were carried out by the two senior authors (BPR and BL). The mean length of admission was 2.7 days (Range 2–5). There have been no infective or thromboembolic complications to date. The mean oxford scores improved from 41 (Range 26–52) pre-operatively to 18 (15–27) at one year follow-up. The mean range of motion improved from 115 degrees of flexion preoperatively to 125 degrees. All radiographs were satisfactory at one year follow up with no evidence of loosening. We report the promising early results of a new medial unicompartmental knee replacement with at least one year follow up. No early complications or infections were identified in our cohort of patients


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_34 | Pages 372 - 372
1 Dec 2013
Nam D Khamaisy S Zuiderbaan H Pearle A
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Introduction:. The number of medial unicompartmental knee arthroplasties (UKA) performed over the last decade has increased by 30%, as studies have demonstrated improved knee kinematics, range of motion, and decreased perioperative morbidity versus total knee arthroplasty. However, concerns remain regarding the future risk of revision due to lateral compartment degeneration. In patients with a varus mechanical alignment and tibiofemoral subluxation secondary to medial compartment osteoarthritis, the femoral and tibial articular surfaces of the lateral compartment subsequently become incongruous, potentially increasing the focal contact stresses seen with loading. The purpose of this study is to evaluate whether the tibiofemoral congruence of the lateral compartment of the knee is improved following a medial UKA. Methods:. This study is a retrospective review of 192 consecutive medial UKAs included in an IRB-approved, single-surgeon database. All UKAs were performed using a robot-assisted surgical technique. Preoperative and postoperative standing, anteroposterior hip-to-ankle radiographs controlling for lower extremity rotation were performed from which the congruence of the lateral compartment was measured. The preoperative and postoperative degree of articular congruence (congruence index, CI) was calculated using an iterative closest point (ICP)-based software code (Matlab, MathWorks Inc., Natick, MA), specially developed to evaluate congruence of knee compartments. Following digitization of the articular surfaces of the femur and tibia, the code performs a rigid transformation that best aligns the articular surfaces and evaluates the current degree of articular congruence. A congruence index (CI) is then calculated, with a value of 1 indicating complete congruence, and a value of 0 indicating a 100% dislocation of the articular surfaces. A student's t-test was used to compare the preoperative and postoperative values of lateral compartment congruence. Results:. The mean, preoperative congruence index of the lateral compartment was 0.88 (± 0.1), which was improved to 0.93 (± 0.07), following implantation of a medial UKA (p < 0.001). Congruence of the lateral compartment was improved in 158 of the UKAs (83%), while 34 (17%) demonstrated a decrease in the congruence index postoperatively. Conclusion:. Implantation of a medial unicompartmental knee arthroplasty improves the articular surface congruence of the lateral compartment in the majority of patients with isolated, medial compartment osteoarthritis (Figure 1). We hypothesize that this factor, combined with a controlled undercorrection of the overall mechanical alignment, will improved load distribution across the lateral compartment, reduce the risk of focal contact stress points, and decrease the risk of subsequent osteoarthritic degeneration of the lateral compartment. Medial UKA not only resurfaces the medial compartment, but also may treat potential lateral compartment degeneration by improving congruence and load distribution


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_5 | Pages 140 - 140
1 Apr 2019
John J Uzoho C Pickering S Straw R Geutjens G Chockalingam N Wilton T
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Background. Alignment and soft tissue (ligament) balance are two variables that are under the control of a surgeon during replacement arthroplasty of the knee. Mobile bearing medial unicompartmental knee replacements have traditionally advocated sizing the prosthesis based on soft tissue balance while accepting the natural alignment of the knee, while fixed bearing prosthesis have tended to correct alignment to a pre planned value, while meticulously avoiding overcorrection. The dynamic loading parameters like peak adduction moment (PKAM) and angular adduction Impulse (Add Imp) have been studied extensively as proxies for medial compartment loading. In this investigation we tried to answer the question whether correcting static alignment, which is the only alignment variable under the control of the surgeon actually translates into improvement in dynamic loading during gait. We investigated the effect of correction of static alignment parameter Hip Knee Ankle (HKA) angle and dynamic alignment parameter in coronal plane, Mean Adduction angle (MAA) on 1st Peak Knee Adduction Moment (PKAM) and Angular Adduction Impulse (Add Imp) following medial unicompartmental knee replacements. Methods. Twenty four knees (20 patients) underwent instrumented gait analysis (BTS Milan, 12 cameras and single Kistler force platform measuring at 100 Hz) before and after medial uni compartmental knee replacement. The alignment was measured using long leg alignment views, to assess Hip Knee Ankle (HKA) angle. Coronal plane kinetics namely 1st Peak Knee Adduction Moment (PKAM) and angular adduction impulse (Add Imp)- which is the moment time integral of the adduction moment curve were calculated to assess medial compartment loading. Single and multiple regression analyses were done to assess the effect of static alignment parameters (HKA angle) and dynamic coronal plane alignment parameters (Mean Adduction Angle – MAA) on PKAM and Add Imp. Results. 12 knees had mobile bearing prosthesis implanted while the other 12 had fixed bearing prosthesis. The mean correction for HKA angle was 2.78 degrees (SD ± 1.32 degrees). There was no significant difference in correction of alignment (HKA) between mobile bearing and fixed bearing groups. MAA and HKA angles were significant predictors of dynamic loading parameters, PKAM and Add Imp (p<0.05). Correction of HKA angle was found to be a better predictor of dynamic loading. We assessed the percentage improvement in loading (%ΔPKAM & %ΔAdd. Imp) and its relationship to correction of HKA (Δ HKA) angle Correction of alignment in the form of HKA (Δ HKA) angle was found to be a very strong predictor of improvement of loads (R = 0.90 for %ΔAdd. Imp and R = 0.50 for %Δ PKAM). Conclusion. Correction of alignment (HKA Angle) predicts improvement in loads through medial compartment of knee. One degree correction resulted in 7% improvement of load through the medial unicompartmental knee replacement


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_6 | Pages 60 - 60
1 Mar 2017
van der List J Pearle A Carroll K Coon T Borus T Roche M
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INTRODUCTION. Successful clinical outcomes following unicompartmental knee arthroplasty (UKA) depend on component positioning, soft tissue balance and lower limb alignment, all of which can be difficult to achieve using manual instrumentation. A new robotic-guided technology has been shown to improve postoperative implant positioning and lower limb alignment in UKA but so far no studies have reported clinical results of robotic-assisted medial UKA. Goal of this study therefore was to assess outcomes of robotic-assisted medial UKA in a large cohort of patients at short-term follow-up. METHODS. This multicenter study with IRB approval examines the survivorship and satisfaction of this robotic-assisted procedure coupled with an anatomically designed UKA implant at a minimum of two-year follow-up. A total of 1007 patients (1135 knees) underwent robotic-assisted surgery for a medial UKA from six surgeons at separate institutions in the United States. All patients received a fixed-bearing metal backed onlay implant as the tibial component between March 2009 and December 2011 (Figure 1). Each patient was contacted at minimum two-year follow-up and asked a series of five questions to determine implant survivorship and patient satisfaction. Survivorship analysis was performed using Kaplan-Meier method and worst-case scenario analysis was performed whereby all patients were considered as revision when they declined study participation. Revision rates were compared in younger and older patients (age cut-off 60 years) and in patients with different body mass index (body mass index cut-off 35 kg/m. 2. ). Two-sided chi-square tests were used to compare these groups. RESULTS. Data was collected for 797 patients (909 knees) with an average follow-up of 29.6 months (range: 22 – 52 months). At 2.5-years follow-up, eleven knees were reported as revised, which resulted in a survivorship of 98.8% (Figure 2). Thirty-five patients declined to participate in the study yielding a worst-case survivorship of 96.0%. Higher revision rates were seen in younger patients (2.60% versus 0.93%, p = 0.09) and in morbidly obese patients (3.36% versus 0.91%, p = 0.03). Of all patients without revision, 92% was either very satisfied or satisfied with their knee function (Figure 3). CONCLUSION. In this multicenter study, robotic-assisted UKA was found to have high survivorship and satisfaction rate at short-term follow-up. Prospective comparison studies with longer follow-up are necessary in order to compare survivorship and satisfaction rates of robotic-assisted UKA to conventional UKA and robotic-assisted UKA to total knee arthroplasty. For any figures or tables, please contact authors directly (see Info & Metrics tab above).


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_9 | Pages 116 - 116
1 May 2016
Park S Jung J
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Purpose. The purpose of the present study was to compare functional outcomes of medial unicompartmental knee arthroplasty (UKA) in patients with lateral meniscal lesion (LM (+) group) in the preoperative MRI and those without lateral meniscal pathology (LM (−) group) and to evaluate the effect of lateral meniscus lesion in preoperative MR on functional outcomes after UKA. Methods. The outcomes of 66 knees (LM (+) group) were compared to the outcomes of 54knees(LM (−) group)with a median follow-up of 28 month(range 24–36 months). Clinical outcomes including KS object score, KS pain score, lateral side pain, physical exam for lateral meniscal lesion and squatting ability. Radiological parameters (mechanical axis and component position) were compared and their effects on functional outcomes were evaluated at the final follow-up visits. Result. At final follow-up visits, no significant intergroup difference was found about KS object score, presence of lateral side pain, positive physical examination for meniscal lesion and squatting ability. LM(+) group had a tendency of more varus postoperative mechanical axis and showed better KS pain score and more comfortable feeling during squatting activity. Furthermore, no correlation was found between postoperative mechanical axis and functional outcome variables. Conclusions. The result of UKA for medial unicompartmental knee osteoarthritis was excellent regardless of preoperative lateral meniscal pathology in the MRI, if patient had not symptoms related to lateral meniscus lesion. Mild varus alignment for those who had a lateral meniscal lesion provided satisfactory clinical outcome of medial UKA


Introduction. In prosthetic knee surgery, the axis of the lower limb is often determined only by static radiographic analysis. However, it is relevant to determine if this axis varies during walking, as this may alter the stresses on the implants. The aim of this study was to determine whether pre-operative measurement of the mechanical femorotibial axis (mFTA) varies between static and dynamic analysis in isolated medial femorotibial osteoarthritis. Methods. Twenty patients scheduled for robotic-assisted medial unicompartmental knee arthroplasty (UKA) were included in this prospective study. We compared three measurements of the coronal femorotibial axis: in a static and weightbearing position (on long leg radiographs), in a dynamic but non-weightbearing position (intra-operative acquisition during robotic-assisted UKA), and in a dynamic and weightbearing position (during walking by a gait analysis). Results. There was no significant difference in the mFTA between radiological (173.9 ± 3.3°), robotic (174.4 ± 3.4°), and gait analysis (172.9 ± 5.1°) measurements (p < 0.05). Conclusion. There is no significant variation in varus between lying, standing, and while walking in patients who are candidates for medial UKA. This study also allows us to validate the accuracy of the robotic system in varus estimation, and to rely on intra-operative planning as it also reflects the dynamic knee under load


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_7 | Pages 30 - 30
1 Jul 2022
Middleton R Jackson W Alvand A Bottomley N Price A
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Abstract. Background. Since 2012 we have routinely used the cementless Oxford medial unicompartmental knee arthroplasty (mUKA), with microplasty instrumentation, in patients with anteromedial osteoarthritis (AMOA) meeting modern indications. We report the 10-year survival of 1000 mUKA with minimum 4-year follow-up. Methods. National Joint Registry (NJR) surgeon reports were interrogated for each senior author to identify the first 1,000 mUKAs performed for osteoarthritis. A minimum of 4 years follow-up was required. There was no loss to follow-up. The NJR status of each knee was established. For each mUKA revision the indication and mechanism of failure was determined using local patient records. The 10-year implant survival was calculated using life-table analysis. Results. The 1,000 mUKA cohort represented 55% of all primary knee replacements in the period, with an average age of 67.7 years and a 54%/46% male/female split. There were 17 revisions (11 for arthritis progression, 4 infections, 1 dislocation and 1 aseptic loosening). The 10-year survival was 98% (44 at risk in 10th year). One patient sustained a periprosthetic fracture at 3 weeks, treated with buttress plate fixation. Discussion. This is the first detailed series reporting the long-term outcome of the cementless Oxford mUKA implanted using microplasty instrumentation. There was a low failure rate, with only one revision for aseptic loosening. Lateral progression was the commonest cause for revision, with an incidence of 1%. This report provides evidence that the combination of evidence-based indications, well-designed instrumentation and cementless fixation can provide excellent long-term survival for the Oxford mUKA in treating AMOA


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 35 - 36
1 Mar 2010
Lanting B Bourne RB Rorabeck CH Guerin J Naudie D
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Purpose: Unicompartmental knee arthroplasty remains a viable treatment modality for arthrosis confined to the medial compartment of the knee. Few studies have reported survivorship of this procedure into the second decade. The purpose of this study was to report our long-term experience with this procedure at a mean follow-up of fifteen years. Method: Between 1989 and 2000, 113 medial unicompartmental knee arthroplasties in 84 patients were performed using the Miller-Galante prosthesis. The 84 patients had an average age of 68 years old at the time of surgery; 45 of which were male and 39 female. At a mean of fifteen-year follow-up, 22 patients (25 arthroplasties) had died, and the remaining 62 patients (88 arthroplasties) were reviewed and evaluated. No patient was lost to follow-up. Results: The mean Knee Society knee and function scores had an improvement from 53 and 48 points pre-operatively to 77 and 90 points respectively at time of most recent evaluation. Twenty unicompartmental knee arthroplasties were revised, at an average of seven years (one to fourteen) following index procedure. The five, ten and fifteen-year rates of survival were 94%, 90%, and 86% respectively with revision to tricompartmental knee arthroplasty as the end point. Conclusion: The Miller-Galante medial unicompartmental knee arthroplasty provided excellent pain relief and restoration of function in carefully selected patients and demonstrated durable implant survival at fifteen years. Progression of arthrosis is the primary mode of failure


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXV | Pages 215 - 215
1 Jun 2012
Shetty G Mullaji A
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Excessive under correction of varus deformity may lead to early failure and overcorrection may cause progressive degeneration of the lateral compartment following medial unicompartmental knee arthroplasty (UKA). However, what influences the postoperative limb alignment in UKA is still not clear. This study aimed to evaluate postoperative limb alignment in minimally-invasive Oxford medial UKAs and the influence of factors such as preoperative limb alignment, insert thickness, age, BMI, gender and surgeon's experience on postoperative limb alignment. Clinical and radiographic data of 122 consecutive minimally-invasive Oxford phase 3 medial unicompartmental knee arthroplasties (UKAs) performed in 109 patients by a single surgeon was analysed. Ninety-four limbs had a preoperative hip-knee-ankle (HKA) angle between 170°-180° and 28 limbs (23%) had a preoperative hip-knee-ankle (HKA) angle <170°. The mean preoperative HKA angle of 172.6±3.1° changed to 177.1±2.8° postoperatively. For a surgical goal of achieving 3° varus limb alignment (HKA angle=177°) postoperatively, 25% of limbs had an HKA angle >3° of 177° and 11% of limbs were left overcorrected (>180°). Preoperative HKA angle had a strong correlation (r=0.53) with postoperative HKA angle whereas insert thickness, age, BMI, gender and surgeon's experience had no influence on the postoperative limb alignment. Minimally invasive Oxford phase 3 UKA can restore the limb alignment within acceptable limits in majority of cases. Preoperative limb alignment may be the only factor which influences postoperative alignment in minimally-invasive Oxford medial UKAs. Although the degree of correction achieved postoperatively from the preoperative deformity was greater in limbs with more severe preoperative varus deformity, these knees tend to remain in more varus or under corrected postoperatively. Overcorrection was more in knees with lesser preoperative deformity. Hence enough bone may need to be resected from the tibia in knees with lesser preoperative deformity to avoid overcorrection whereas limbs with large preoperative varus deformities may remain under corrected


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_3 | Pages 52 - 52
1 Jan 2016
Mori M Mashiba T
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Purpose. In this study, we report the clinical results of medial UKA in combination with patellofemoral arthroplasty (MUKA/PFA) in 7 cases of bicompartmental osteoarthritis. Subjects and Methods. Seven patients who received MUKA/PFA between June 2011 and April 2012 were included into the study. There were 1 male and 6 females with an average age of 77 years at time of operation. All those patients were suffering end stage osteoarthritis of both medial and patellofemoral compartments, with obvious clinical and radiological findings. The average follow-up period was 7 months. Patients were clinically examined including JOA score and range of motion (ROM) and radiographs were evaluated. Results. The mean JOA score improved from a preoperative 55.7 points to 84.4 points at latest follow-up. The mean knee extension angle improved from −4.3? preoperatively to 0?postoperatively, and flexion was almost unchanged from 129.3? to 132.9?. The only complication we experienced was progression of degenerative changes in the lateral compartment in one ACL deficient knee of a 90-years-old female. The mean femoro-tibial angle was corrected from 179.3? to 173.3?. Patello-femoral alignment was improved by the surgery in all knees. Conclusions. Our results showed that MUKA/PFA is a successful solution for bicompartmental osteoarthiritis of the knee with the involvements of medial femorotibial and patellofemoral joints, and may provide better patient satisfaction then does TKA, although operative criteria for this procedure must be strict. Longer-term follow-up will also be necessary to prove the validity of this procedure


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_16 | Pages 19 - 19
1 Oct 2017
Masud S Guro R Mohan R Chandratreya A
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Oxford Medial Unicompartmental Knee Replacement (OMUKR) is a well-established treatment option for isolated medial compartment arthritis, with good patient reported outcome measures (PROMs). We present our results of the Oxford Domed Lateral Unicompartmental Knee Replacement (ODLUKR) to establish if patients benefit as much as with OMUKR. Retrospective review of prospectively collected data of a single surgeon series of consecutive UKR from 2007 to 2014 were collated with a minimum 2 years follow-up. PROMs data were collected using pre- and post-operative Oxford Knee Scores (OKS) (best score of 48). One hundred and twenty-eight OMUKR and 27 ODLUKR were performed in the study period. There was no significant difference in the age at time of surgery, but there were significantly more women in the ODLUKR group (74% vs 53%). There was no significant difference in pre-op OKS between the groups (OMUKR = 16/48; ODLUKR = 20/48), or the improvement in OKS post-op (OMUKR = 19 points; ODLUKR = 17 points). One ODLUKR was revised to Total Knee Replacement (TKR) for pain. There were three (11.1%) bearing dislocations, which were treated with thicker bearing exchange, with no subsequent problems. There were no bearing dislocations in the OMUKR. Four OMUKR were revised to TKR due to pain. The overall implant survivorship was 96.3% for ODLUKR and 96.9% for OMUKR. ODLUKR is a good treatment option for isolated lateral compartment arthritis and gives results equivalent to OMUKR. There is, however, an increased risk of bearing dislocation so should be performed by a high volume UKR surgeon