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Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_8 | Pages 22 - 22
1 Apr 2017
Jones M Parry M Whitehouse M Blom A
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Background

Frequency of primary total hip (THA) and total knee (TKA) arthroplasty procedures is increasing, with a subsequent rise in revision procedures. This study aims to describe timing and excess surgical mortality associated with revision THA and TKA compared to those on the waiting list.

Methods

All patients from 2003–2013 in a single institution who underwent revision THA and TKA, or added to the waiting list for the same procedure were recorded. Mortality rates were calculated at cutoffs of 30- and 90-days post-operation or addition to the waiting list.


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_11 | Pages 53 - 53
1 Nov 2022
Saxena P Ikram A Bommireddy L Busby C Bommireddy R
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Abstract. Introduction. There is paucity of evidence in predicting outcomes following cervical decompression in patients in octogenerians with cervical myelopathy. Our aim is to analyse the predictive value of Charlson comorbidity index (CCI) on clinical outcomes in this group. Methods. All patients age >80 years who underwent cervical decompression+/−stabilisation between January 2006-December 2021 at University Hospitals of Derby & Burton were included. Logistic regression analysis was performed using JASP. Results. Total 72 patients (n=32 male, n=28 female). Mean age 83.44 ± 3.21 years. 67 patients underwent posterior decompression+ stabilisation & 5 patients had posterior decompression alone. Mean CCI was 5; graded moderate in 32 (44%, CCI=<4) and severe in 40 (55.5%, CCI>4). Mean age and preoperative Nurick grade was similar between moderate and severe groups. Postoperative Nurick grade improved equally in both groups by 0.67 and 0.68 respectively (p=0.403). Mean LOS 16±16.12 days. 5 complications in the moderate group (21.8%) and 8 complications in severe group (21.6%); wound infection (n=7), other infection (n=2), electrolyte derangement (n=2), AKI (n=1), blood transfusion (n=1) and early death (n=3) (p=0.752). 1 early postoperative death <30 days occurred in the moderate group (4.3%) whereas 2 occurred in the severe group (5.3%) (p=0.984). No patients with moderate CCI required nursing home discharge whereas 7.9% of severe patients required this. Conclusion. Both groups benefitted from neurological improvement postoperatively, low 1 year mortality. No difference in hospital stay, complication rate and early mortality between both groups. More patients with severe CCI require nursing care after discharge than those with moderate CCI


Bone & Joint Open
Vol. 5, Issue 2 | Pages 87 - 93
2 Feb 2024
Wolf O Ghukasyan Lakic T Ljungdahl J Sundkvist J Möller M Rogmark C Mukka S Hailer NP

Aims. Our primary aim was to assess reoperation-free survival at one year after the index injury in patients aged ≥ 75 years treated with internal fixation (IF) or arthroplasty for undisplaced femoral neck fractures (uFNFs). Secondary outcomes were reoperations and mortality analyzed separately. Methods. We retrieved data on all patients aged ≥ 75 years with an uFNF registered in the Swedish Fracture Register from 2011 to 2018. The database was linked to the Swedish Arthroplasty Register and the National Patient Register to obtain information on comorbidity, mortality, and reoperations. Our primary outcome, reoperation, or death at one year was analyzed using restricted mean survival time, which gives the mean time to either event for each group separately. Results. Overall, 3,909 patients presenting with uFNFs were included. Of these patients, 3,604 were treated with IF and 305 with primary arthroplasty. There were no relevant differences in age, sex, or comorbidities between groups. In the IF group 58% received cannulated screws and 39% hook pins. In the arthroplasty group 81% were treated with hemiarthroplasty and 19% with total hip arthroplasty. At one year, 32% were dead or had been reoperated in both groups. The reoperation-free survival time over one year of follow-up was 288 days (95% confidence interval (CI) 284 to 292) in the IF group and 279 days (95% CI 264 to 295) in the arthroplasty group, with p = 0.305 for the difference. Mortality was 26% in the IF group and 31% in the arthroplasty group at one year. Reoperation rates were 7.1% in the IF group and 2.3% in the arthroplasty group. Conclusion. In older patients with a uFNF, reoperation-free survival at one year seems similar, regardless of whether IF or arthroplasty is the primary surgery. However, this comparison depends on the choice of follow-up time in that reoperations were more common after IF. In contrast, we found more early deaths after arthroplasty. Our study calls for a randomized trial comparing these two methods. Cite this article: Bone Jt Open 2024;5(2):86–92


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 263 - 263
1 May 2006
Hinsley D Tam W Evison D
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Objectives: Behind armour blunt trauma (BABT) to the thorax results from motion of the body wall arising from the defeat of high-energy projectiles by body armour. NATO predicts that BABT will increase in future conflicts. This study aims to define biomechanical tolerance levels for BABT to the lateral thorax. Methods: Terminally anaesthetised pigs (n=19) were subjected to 4 levels of severity of BABT (Table). Two types of armour plates were used. Group 1 were subjected to a 7.62 mm round (INIBA armour) whilst group 2 was subjected to a 12.7 mm round (EBA armour) the latter group being further subdivided by the presence or absence of two thicknesses of trauma attenuating backing (TAB). Accelerometers were attached to the pleural aspect of ribs 7, 8 and 9 mid-way between the spine and the sternum. Results: Outcome was assessed by classifying severity of injury, in terms of mortality, into 3 groups – survivors (animals surviving to 6 h post-impact), early (0–30 min) and late deaths (> 30 min–6 h). The peak acceleration values were obtained from the accelerometer closest to the point of impact. Mean peak acceleration was significantly higher in the early death group (1070 km/s. 2. ) compared to survivors (591 km/s. 2. ) (p< 0.05). There were 6 early deaths, 5 late deaths and 8 survivors. In terms of outcome Group 1 represented the lowest threat with 5 survivors and 1 late death. The animals in Group 2 with no TAB fared worst with 2 early deaths, one late death and no survivors. Deaths were due to respiratory failure/apnoea (n=4), pneumothorax (n=2), haemothorax (n=1), respiratory failure/pulmonary contusion (n=3) and ventricular fibrillation (n=1). Conclusions: Peak acceleration of the body wall may be used to rank the outcome following BABT. There is a significant difference in peak acceleration at the extremes of the injury scale


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_18 | Pages 9 - 9
1 Dec 2018
Downie S Adamson D Jariwala A
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Early mortality in patients with hip fractures due to bony metastases is unknown. The aim was to quantify 30 and 90-day mortality in patients with metastatic hip fractures and identify markers associated with early death. Consecutive patients referred to orthopaedics with a metastatic proximal femoral fracture/impending fracture over a six-year period were compared to a matched control group of non-malignant hip fractures. Minimum follow-up was 1 year and data was analysed using the student´s t-test (significance p<0.05). From Jan 2010-Dec 2015, 163 patients were referred with metastatic proximal femoral lesions. 90-day mortality was three times higher than controls (44% 71/163 vs. 12% 4/33, p<0.01). Mean time from referral to surgery was longer in impending versus completed fractures (11 and 4 days respectively, p<0.05). Multiple biochemical markers were associated with early mortality in the metastatic group. Patients who died early were more likely to demonstrate low haemoglobin and albumin, and high c-reactive protein, platelets, urea, alkaline phosphatase and calcium (p<0.05). Several biochemical markers associated with early mortality reached clinical and statistical significance. These markers were combined into a score out of 7 and indicated a higher early mortality in metastatic patients compared to controls. Patients with a score of 5–6/7 were 31 times more likely to die within 90 days versus controls. This scoring system could be utilised to predict early mortality and guide management. The average delay to surgery of 4 days (completed) and 11 days (impending fractures) identifies a window to intervene and correct these abnormalities to improve survival


The Bone & Joint Journal
Vol. 105-B, Issue 9 | Pages 1013 - 1019
1 Sep 2023
Johansen A Hall AJ Ojeda-Thies C Poacher AT Costa ML

Aims

National hip fracture registries audit similar aspects of care but there is variation in the actual data collected; these differences restrict international comparison, benchmarking, and research. The Fragility Fracture Network (FFN) published a revised minimum common dataset (MCD) in 2022 to improve consistency and interoperability. Our aim was to assess compatibility of existing registries with the MCD.

Methods

We compared 17 hip fracture registries covering 20 countries (Argentina; Australia and New Zealand; China; Denmark; England, Wales, and Northern Ireland; Germany; Holland; Ireland; Japan; Mexico; Norway; Pakistan; the Philippines; Scotland; South Korea; Spain; and Sweden), setting each of these against the 20 core and 12 optional fields of the MCD.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_18 | Pages 2 - 2
1 Nov 2016
Downie S Adamson D Jariwala A
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There is comprehensive data addressing the 6 to 18-month survival in patients with pathological neck of femur (NOF) fractures due to bony metastases. However, little is known about early mortality in this group. The aim was to quantify 30 and 90-day mortality in patients with pathological NOF lesions/fractures and identify biochemical markers associated with early death. Orthopaedic trauma lists over one year were used to identify patients with a pathological NOF fracture/lesion. 33 patients had a metastatic NOF fracture/lesion and were compared to a control group of age and gender-matched non-pathological NOF fractures. Time from referral to surgery was higher in patients with a pathological fracture compared to a pathological lesion (average 7.4 and 0.6 days, p<0.05). 30 and 90-day mortality was higher in the metastatic group compared to controls (15% 5/33 vs 9% 3/33 p<0.05, and 42% 14/33 vs 12% 4/33 p<0.01, respectively). Patients with early mortality had lower average sodium (135 vs 138, p<0.05), creatinine (48 vs 62, p<0.05) and APTT (27 vs 32, p<0.05). They had a higher average WCC (11.3 vs 7, p<0.05) and CRP (55 vs 18, p<0.01). Metastatic patients with early mortality had lower albumin (20 vs 30, p<0.01) and haemoglobin (102 vs 121, p<0.01), which were higher in the control NOF group with early mortality (albumin 28 and haemoglobin 118 respectively, p<0.05). Patients with pathological NOF lesions have multiple biochemical abnormalities associated with early mortality. A prospective study is proposed to assess whether correction of these abnormalities can improve survival in this group


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_10 | Pages 1 - 1
1 Feb 2013
Baird E Macdonald D Gilmour A Kumar C
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We reviewed the outcome of Agility total ankle replacements carried out in our institution between 2002 and 2006. Follow-up consisted of clinical and radiological review pre-operatively, at 6 weeks, 6 and 12 months, and annually until 10 years post-op. Clinical review included the American Orthopaedic Foot and Ankle Score, satisfaction and pain scores. 30 arthroplasties were performed in 30 consecutive patients. Pre-operative diagnosis was rheumatoid arthritis (16), primary osteoarthritis (12) and post-traumatic osteoarthritis (2). After a mean follow up of 6.2 years (1.4–10.1), 4 patients had died, and 20 out of the remaining 24 were available for follow-up. Complications included lateral malleoli fracture (3), superficial peroneal nerve injury (2), one early death, unrelated to the surgical procedure, delayed syndesmotic union (1), non-union (6) and deep infection (2), of which one underwent removal of the implant; the other receives long-term oral antibiotics. AOFAS scores improved from mean 40.4 pre-op to 83.5 post-op (p<0.001). Radiological assessment revealed 25 (93%) patients had lucency in at least one zone in the AP radiograph. We found a relatively high level of re-surgery and complications following Agility total ankle replacement. A 7% revision rate is much higher than would be tolerated in knee or hip arthroplasty, but compares favourably to other studies of TAR. Despite radiological loosening, and the high rate of re-surgery and complications; patients are generally satisfied with the procedure, reporting lower levels of pain and improved function. Overall, we feel that the Agility ankle is an acceptable alternative to arthrodesis, however patients should be warned of the risk of re-surgery


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_30 | Pages 39 - 39
1 Aug 2013
Baird E Macdonald D Gilmour A Kumar C
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We aimed to review the outcome of Agility total ankle replacements carried out in our institution between 2002 and 2006. Follow-up consisted of clinical and radiological review pre-operatively, then at 6 weeks, 6 and 12 months, and annually until 10 years post op. Clinical review included the American Orthopaedic Foot and Ankle Score, satisfaction and pain scores. Case notes were reviewed to determine intra and post-operative complications. 30 arthroplasties were performed in 30 consecutive patients. Pre-operative diagnosis was rheumatoid arthritis(16), primary osteoarthritis(12) and post-traumatic osteoarthritis(2). After a mean follow up of 6.2 years (1.4–10.1), 4 patients had died, and 22 out of the remaining 24 were available for follow-up. Intra operative complications included lateral malleoli fracture(3) and superficial peroneal nerve injury(2). Post operative complications included 1 early death, but this was not related to the surgical procedure. Two patients developed deep infections of the prosthesis. One underwent removal of the implant; the other is on long term oral antibiotic therapy. One patient had delayed union of the syndesmosis and six patients had non-union. On clinical assessment, patients' AOFAS scores improved from mean 40.4 pre-op to 83.5 post-op (p<0.001). Radiological assessment of the tibial component revealed 25 (93%) patients had lucency in at least one zone in the AP radiograph. We found a relatively high level of re-surgery and complications following Agility total ankle replacement. A 7% revision rate is much higher than would be tolerated in knee or hip arthroplasty, but compares favourably to other studies of TAR. Despite radiological features which suggest loosening, the high rate of re-surgery and complications; patients are generally satisfied with the procedure, reporting lower levels of pain and improved function. Overall we feel that the Agility ankle is an acceptable alternative to ankle arthrodesis, however patients need to be warned of the risk of re-surgery


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 58 - 58
1 Jan 2013
Baird E Macdonald D Gilmour A Kumar C
Full Access

We aimed to review the outcome of Agility total ankle replacements carried out in our institution between 2002 and 2006. Follow-up consisted of clinical and radiological review pre-operatively, then at 6 weeks, 6 and 12 months, and annually until 10 years post op. Clinical review included the American Orthopaedic Foot and Ankle Score, satisfaction and pain scores. Case notes were reviewed to determine intra and post-operative complications. 30 arthroplasties were performed in 30 consecutive patients. Pre-operative diagnosis was rheumatoid arthritis(16), primary osteoarthritis(12) and post-traumatic osteoarthritis(2). After a mean follow up of 6.2 years (1.4–10.1), 4 patients had died, and 22 out of the remaining 24 were available for follow-up. Intra operative complications included lateral malleoli fracture(3) and superficial peroneal nerve injury(2). Post operative complications included 1 early death, but this was not related to the surgical procedure. Two patients developed deep infections of the prosthesis. One underwent removal of the implant; the other is on long term oral antibiotic therapy. One patient had delayed union of the syndesmosis and six patients had non-union. On clinical assessment, patients' AOFAS scores improved from mean 40.4 pre-op to 83.5 post-op (p< 0.001). Radiological assessment of the tibial component revealed 25 (93%) patients had lucency in at least one zone in the AP radiograph. We found a relatively high level of re-surgery and complications following Agility total ankle replacement. A 7% revision rate is much higher than would be tolerated in knee or hip arthroplasty, but compares favourably to other studies of TAR. Despite radiological features which suggest loosening, the high rate of re-surgery and complications; patients are generally satisfied with the procedure, reporting lower levels of pain and improved function. Overall we feel that the Agility ankle is an acceptable alternative to ankle arthrodesis, however patients need to be warned of the risk of re-surgery


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_III | Pages 129 - 129
1 Feb 2012
Dawson-Bowling S Chettiar K Cottam H Fitzgerald-O'Connor I Forder J Worth R Apthorp H
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This study aims to assess prospectively whether measurement of perioperative Troponin T is a useful predictor of potential morbidity and mortality in patients undergoing surgery for fractured neck of femur. All patients aged 65 years and over presenting with a fractured neck of femur over a 4-month period were initially included. Exclusion criteria were renal failure, polymyositis and conservative fracture management. Troponin T levels were measured on admission, day 1 and 2 post-surgery. According to local protocol, a level of >0.03ng/mL was considered to be raised. Outcome measures adverse were cardiorespiratory events (myocardial infarction, congestive cardiac failure, unstable angina, major arrhythmias requiring treatment and pulmonary embolism), death and length of inpatient stay. 108 patients were recruited after application of the exclusion criteria. 42 (38.9%) showed a rise in Troponin T >0.03ng/mL in at least one sample. Of these, 25 (59.5%) sustained at least outcome complication, as opposed to 7 (10.6%) from the group with no Troponin T rise (p<0.001). The mean length of stay was 25.7 days for patients with elevated Troponin T levels, compared with 18.3 days in the normal group (p<0.012). There were 9 deaths in the raised Troponin group (21.4%), and 5 (7.6%) in the group with no rise (p<0.05). The principal causes of early death after hip fracture surgery are cardiac failure and myocardial infarction. Troponin T is a sensitive enzymatic marker of myocardial injury. The association between raised Troponin and hip fractures has not previously been made. In our series, 38.9% showed a perioperative Troponin rise. This was significantly associated with increased morbidity, mortality and longer hospitalisation. Many hip fracture patients appear to be having silent cardiorespiratory events, contributing significantly to perioperative morbidity. We recommend measurement of Troponin levels in all such patients to identify this risk and initiate appropriate treatment


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 261 - 261
1 Mar 2004
Kalliopi P Ch B Karamoulas V Papaioannou T Antonopoulou E
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Aims: To elicit the predisposing factors responsible for early death in the aged population with hip fracture. Methods: In this perspective study we dealed with 65 patients over 65 years old (51 women) with mean age 80.1 years old (65 – 104) who suffered a hip fracture (34 trochanteric and 31 subcapital). We studied age, sex, ASA score, delay for surgery and mobility preoperatively, blood loss and operative time interoperatively and postoperative delirium and fixation failure. Haemoglobin, WBC, serum albumin and Mini Mental Test were recorded both pre and postoperatively. The place of the accident was also recorded. The above parameters were compared for survivors and non-survivors patients. Results: 11 patients died during the first 6 months with a mortality rate 16.9%. In all other parameters we detected no significant differences between groups. Conclusions: The failure pattern (deaths) after a hip fracture during the first 6 months postoperatively included female of advanced age, with dementia and medical problems (ASA), who developed delirium postoperatively and had diminished preoperatively mobility


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 165 - 165
1 Mar 2009
Dawson-Bowling S Chettiar K Cottam H Forder J Worth R Apthorp H
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This study aims to assess prospectively whether measurement of peripoperative Troponin T is a useful predictor of potential morbidity and mortality in patients undergoing surgery for fractured neck of femur. All patients aged 65 years and over presenting with a fractured neck of femur over a 4-month period were initially included. Exclusion criteria were renal failure, polymyositis and conservative fracture management. Troponin T levels were measured on admission, day 1 and 2 post surgery. According to local protocol, a level of > 0.03ng/mL was considered to be raised. Outcome measures adverse were cardiorespiratory events (myocardial infarction, congestive cardiac failure, unstable angina, major arrhythmias requiring treatment and pulmonary embolism), death and length of inpatient stay. 108 patients were recruited after application of the exclusion criteria. 42 (38.9%) showed a rise in Troponin T > 0.03ng/mL in at least one sample. Of these, 25 (59.5%) sustained at least outcome complication, as opposed to 7 (10.6%) from the group with no Troponin T rise (p< 0.001). The mean length of stay was 25.7 days for patients with elevated Troponin T levels, compared with 18.3 days in the normal group (p< 0.012). There were 9 deaths in the raised Troponin group (21.4%), versus 5 (10.6%) in the group with no rise (p< 0.05). The principle causes of early death after hip fracture surgery are cardiac failure and myocardial infarction. Troponin T is a sensitive enzymatic marker of myocardial injury. The association between raised Troponin and hip fractures has not previously been made. In our series, 38.9% showed a perioperative Troponin rise. This was significantly associated with increased morbidity, mortality and longer hospitalisation. Many hip fracture patients appear to be having silent cardiorespiratory events, contributing significantly to perioperative morbidity. We recommend measurement of Troponin levels in all such patients to identify this risk and initiate appropriate treatment


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 335 - 335
1 Mar 2004
Lindahl J Porras M Hirvensalo E
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Aims: To evaluate the outcome after early angiographic embolization in pelvic ring injuries associated with massive bleeding. Methods: We evaluated prospectively 32 consecutive patients. Special attention was paid to the þndings in angiography, the reliability of embolization, and the þnal result (survive or death). The causes of deaths were evaluated as well as the parameters correlating to this. Results: Angiography showed an isolated arterial injury in 16 (50%) and multiple arterial injuries also in 16 patients (50%). 9 patients had bilateral bleeding. Internal iliac artery and/or its main branches was the source of bleeding in 27 (85%), external iliac artery or its main branches in 2 (6%), and branches of both internal and external iliac arteries in 3 patients (9%). The embolization was successful in all cases. 11 patients (34%) died. The early deaths (< 24h) were the result of massive bleeding in 4 out of 5 patients. One died to cardiac failure. Six late deaths were the result of MODS. All the died patients had more than one bleeding artery, and 6 had bilateral bleeding. The non-survivors had more severe injuries (mean ISS 51) and were older (mean age 50,2 yrs) than the survivors (mean ISS 41; mean age 43,9 yrs). Conclusions: Angiographic embolization is an effective and life saving procedure. It should be considered in hypotensive patients with unstable pelvic ring injuries who remain haemodynamically unstable following adequate resuscitation with component therapy and external þxation


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 162 - 162
1 Mar 2006
Loupasis G Anastopoulos G Solomos P Deros J Biniaris G Assimakopoulos A
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Aim: To review the operative results and to determine factors that may significantly influence the outcome. Method: We retrospectively reviewed 38 patients treated with femoral interlocking nailing and tibial external fixation in a 5-year period (1996–2000). Two patients were excluded because of early death. Minimum follow-up was 2 years. There were 29 men and 7 women with a mean age of 27 years. Eight femoral (22%) and 29 tibial fractures (81%) were open. Associated injuries to th head, chest, and abdomen were seen in 17 patients (47%). Concomitant musculoskeletal trauma was present in 30 patients (83%). Final functional results were evaluated according to Karlstrom’s and Olerud’s criteria. Various factors were assessed including age, severity of open fractures, neurovascular injuries, fracture comminution, ligamentous knee injuries, concomittant injuries in the same limb or in the contralateral limb, existence of multiple trauma. Multivariate models were derived to detetermine predictors of outcome. Results: All femoral fractures and 31 tibial fractures (86%) united without additional intervention. Radiographic femoral union averaged 14 weeks and tibial union 20 weeks. A total of 18 secondary procedures were required. Functional results were excellent or good in 26 patients (72%). Increasing age, fracture comminution and associated injury in the contralateral limb were not influenced the final result. Open grade III tibial fractures (p< 0.03), severity of knee ligamentous injury (p< 0.02) and concomitant trauma to the same extremity (particularly to the ankle and foot – p< 0.02), contributing significantly to an unsatisfactory outcome


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 301 - 301
1 Jul 2008
Dawson-Bowling S Chettiar K Cottam H Worth R Forder J Fitzgerald-O’Connor I Apthorp H
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Introduction: The principle causes of early death after hip fracture surgery are cardiac failure and myocardial infarction. Troponin T is a sensitive and specific enzymatic marker of myocardial injury. This study aims to assess prospectively whether Troponin T may be used as a predictor of morbidity and mortality in admissions with fractured neck of femur. Methods: All patients aged 65 years and over presenting with a fractured neck of femur over 4 months were included. Exclusion criteria of polymyositis, renal failure and conservative fracture management were applied. Troponin T levels were measured on admission, and days 1 and 2 post surgery. According to local protocol, a level of > 0.03ng/mL was considered to be raised. Outcome measures were defined as adverse cardiorespiratory events (myocardial infarction, congestive cardiac failure, unstable angina, major arrhythmias requiring treatment and pulmonary embolism), death and length of inpatient stay. Results: 108 patients were recruited over the 4 months. 42 (38.9%) showed a rise in Troponin T > 0.03ng/mL in at least one sample. Of these, 25 (59.5%) sustained at least one of the outcome complications including death, as opposed to 7 (10.6%) from the group with no Troponin rise (p< 0.001). The mean inpatient stay was 25.7 days for patients with elevated Troponin T levels, compared with 18.3 days in the normal group (p< 0.012). There were 9 deaths in the raised Troponin group (21.4%), and 5 (10.6%) in the group with no rise (p< 0.05). Discussion: The association between raised Troponin and hip fractures has not previously been made. Many patients appear to be having silent cardiorespiratory or related events, which may be a significant cause of perioperative morbidity and mortality. We propose measurement of Troponin levels as part of the standard perioperative screening for hip fracture patients to identify this risk and initiate appropriate treatment measures


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 291 - 291
1 May 2010
Wylde V Parry M Blom A
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Introduction: Venous thromboembolism is a major cause of morbidity and mortality in hospitalised patients and patients undergoing major orthopaedic surgery are at high risk from venous thromboembolism. Thromboprophylaxis, both mechanical and chemical, is commonly administrated to reduce fatality from thromboembolism after surgery. However, there is no convincing evidence in the literature demonstrating that routine chemothromboprophylaxis reduces death rates from pulmonary embolus. Furthermore, it is unclear from the literature which thromboprophylactic agent, if any, should be used. Recent NICE guidelines have recommended that heparin should be routinely administered to patients under-going THR to prevent thromboembolism, although it is unclear from the existing evidence if heparin is the most effective. However, research has suggested that aspirin, which is a low cost prophylactic agent, is effective in preventing DVT and PE after orthopaedic surgery. The aim of this study was to determine the 90-day mortality rate after THR using aspirin as a prophylactic agent. Patients and Methods: Between 2003–2006, 2,286 patients underwent primary THR and 372 patients underwent revision hip replacement (RHR). Routine chemothromboprophylaxis consisting of aspirin 75mg daily for 6 weeks. In addition all patients were treated with anti-thromboembolic stockings. 40mg of subcutaneous clexane, in lieu of aspirin, was given daily to all patients who had previously suffered from a pulmonary embolus or deep venous thrombosis. Patients who died within 90 days of surgery had their death certificates examined. Retrieval at 90 days with regard to death was 100%. Results:. Primary THR. One patient (0.04%) died within 30 days of surgery and a further 3 (0.13%) died between day 30 and day 90, giving a total mortality at 90 days of 0.17% (4/2,286). One patient (0.04%) died from PE and the other 3 patients (0.13%) died from non-vascular causes. Revision hip replacement. One patient (0.27%) died within 30 days of surgery and a further 1 patient (0.27%) died between day 30 and day 90, giving a total mortality at 90 days of 0.54% (2/367). Both patients died from non-vascular causes. Discussion: This study found that the 30-day mortality rate for primary THR and RHR was 0.08% and the 90-day mortality rate was 0.23%. In this study, there was only one death from PE and no deaths from arterial complications. Therefore, although NICE guidelines suggest the use of heparin, this study found that routine aspirin administration is beneficial in protecting against early death after THR because of both thromboembolism and adverse arterial events


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 87 - 87
1 Mar 2008
Beadel G Griffin A Ogilvie C Wunder J Bell R
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A retrospective review of our prospectively collected database was undertaken to determine the functional and oncologic outcome following combined pelvic allograft and total hip arthroplasty (THA) reconstruction of large pelvic bone defects following tumour resection. There were twenty-four patients with a minimum followup of fifteen months. The complication rate following hemipel-vic allograft and THA reconstruction of resection Types I+II and I+II+III was high, but when successful this reconstruction resulted in reasonable functional outcome. In comparison, the functional outcome after allograft and THA reconstruction of isolated Type II acetabular resections was better and more predictable. Resection of large pelvic bone tumours often results in segmental defects with pelvic discontinuity and loss of the acetabulum. We reviewed the functional and oncologic outcomes following pelvic allograft and total hip arthroplasty (THA) reconstruction. Reconstruction of large pelvic defects including the acetabulum using hemipelvic allograft and THA is associated with high complication rates, however when successful provides reasonable function. In comparison, the outcomes of allograft and THA for acetabular defects alone are better and more predictable. A retrospective review of our prospectively collected database was undertaken. Minimum followup was fifteen months (15–167). Nineteen patients were hemipel-vic resections (twelve Type I+II and seven Type I+II+III, eleven cases including partial sacral resection) reconstructed by hemipelvic allograft and THA. Five patients had Type II acetabular resections, reconstructed with structural allograft, roof ring and THA. Osteosarcoma and chondrosarcoma were the most frequent tumours. All patients required walking aids. In the hemipelvic group there were two early deaths (peri-operative haemorrhage and aplastic anaemia). In seven patients (37%) the allograft remained intact without infection but three required revision THA for loosening. For these seven patients the functional outcome scores were TESS 64%, MSTS87 17/35 and MSTS93 of 45% (mean fifty-two months.). There were nine cases of deep infection (47%) with three patients maintaining a functional implant. The nineteenth patient was revised following allograft fracture. In the Type II acetabular group, three patients had no complications, and two patients dislocated. The average scores were TESS 78%, MSTS87 21/35 and MSTS93 64% (mean fifty-five months)


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 297 - 298
1 Sep 2005
Beadel G Griffin A Wunder J Bell R Ogilvie C
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Introduction and Aims: Resection of large pelvic bone tumors often results in segmental defects with pelvic discontinuity and loss of the acetabulum. We reviewed the functional and oncologic outcomes following pelvic allograft and total hip arthroplasty (THA) reconstruction. Method: A retrospective review of our prospectively collected database was undertaken. Minimum follow-up was 15 months (range 15–167 months). Nineteen patients were hemipelvic resections (12 Type I+II and seven Type I+II+III, 11 of these cases included partial sacral resection) reconstructed by hemipelvic allograft and THA. In comparison, five patients had Type II acetabular resections, reconstructed with structural allograft, roof ring and THA. Functional outcome was assessed by the Toronto Extremity Salvage score (TESS) and the Musculoskeletal Tumor Society scores (MSTS87 and MSTS93). Results: Osteosarcoma and chondrosarcoma were the most frequent tumors. All patients required walking aids. In the hemipelvic group there were two early deaths (peri-operative haemorrhage and aplastic anaemia). In seven patients (37%), the allograft remained intact without infection but three required revision THA for component loosening. For these seven patients, the functional outcome scores were TESS 64%, MSTS87 17/35 and MSTS93 45% (mean follow-up 52 months). There were nine cases of deep infection (47%) with three patients maintaining a functional implant with antibiotic suppression. Of the remaining six patients with infection, four patients required hindquarter amputation, one patient required allograft removal and the allograft fragmented in the remaining patient. The 19th patient was revised following allograft fracture. Five patients sustained at least one allograft fracture. In the Type II acetabular group, three patients had no complications, and two patients sustained dislocations. The average scores were TESS 78%, MSTS87 21/35 and MSTS93 64% (mean follow-up 55 months). Conclusion: Reconstruction of large pelvic defects including the acetabulum using hemipelvic allograft and THA is associated with high complication rates, however when successful provides reasonable function. In comparison, the functional outcome after allograft and THA reconstruction of isolated Type II acetabular resections was better and more predictable


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_I | Pages 37 - 37
1 Jan 2004
Cochu G Baertich C Fiorenza F Charissoux J Arnaud J Mabit C
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Purpose: The purpose of this study was to assess outcome after first-intention total hip arthroplasty for fresh fractures of the acetabulum in elderly patients. Material and methods: We present a retrospective analysis of 18 recent fractures of the acetabulum observed in nine men and nine women, mean age 74.8 years which were treated by first-intention total hip arthroplasty. The fractures were considered equivalent to acetabular bone deficits observed at revision of total arthroplasty (five grade III, 13 grade IV in the SOFCT 1988 classification). The prosthesis was implanted 15.6 days (mean) after initial trauma and included a metal-backed acetabular implant (except one case) and a bone autograft (except three cases). Complete weight bearing was authorised on day 3 postop for five patients, and at six weeks for ten; at three months for the other three. Mean follow-up was 2.5 years. Thirteen surviving patients were reviewed clinically and radiographically. Five patients who had died were also included in the analysis using data reported by family before death. The Postel-Merle d’Aubigné (PMA) and Harris scores were recorded. Survival curves were plotted. Radiological assessment included bone healing, status of the prosthetic assembly, presence of a lucent line or signs of loosening in the three acetabular zones described by De Lee and Charnley. Results: The mean functional scores were 13.6/18 (PMA) and 71.8/100 (Harris). There were no cases of infection or dislocation. Median Kaplan-Meier survival was six years. The one-year survival rate was 94.4%. Five deaths were recorded, all due to causes independent of the surgical intervention. Radiologically, all fractures had healed. There were no mechanical complications and no signs of acetabular loosening. Discussion: Several authors have demonstrated that prognosis is poor in elderly subjects undergoing surgical osteosynthesis or functional treatment due to the presence of risk factors (osteoporosis, comminution, deferred surgery due to poor general status). Prolonged bed rest may also have life-threatening consequences. Other work has emphasised the very high rate of complications after revision surgery for dismounted material, post-traumatic deterioration, or osteonecrosis. The absence of early deaths and the low rate of intervention-related morbidity in this series of elderly patients is in agreement with a very small number of publications devoted to this topic. Conclusion: This therapeutic attitude enables early verticalisation avoiding the complications related to the bedridden state in the elderly. In addition, subsequent revision for osteonecrosis of the femoral head or post-traumatic deterioration can be avoided. These results have incited us to pursue this therapeutic option