Background

Cam morphology develops during adolescence and predisposes individuals to future hip pain and osteoarthritis. An improved understanding of cam development is required to determine whether the process is modifiable.

Hypothesis/Purpose

The aim of this study was to characterise the risk factors, timing, and pathogenesis of cam formation.

Objectives

The aim of this study was to use registry data to report and compare early patient outcomes following arthroscopic repair or debridement of the acetabular labrum.

Methods

Data on adult patients who underwent arthroscopic labral debridement or repair between January 2012 and March 2019 was extracted from the UK Non-Arthroplasty Hip Registry dataset. Patients who underwent microfracture, osteophyte excision or a concurrent extra-articular procedure were excluded. Outcomes comprised EuroQol-5 Dimensions (EQ-5D) index and the International Hip Outcome Tool 12 (iHOT-12), preoperatively and at 6 and 12 months.

Introduction

Dislocated hip hemiarthroplasties (HA) are associated with a 45% revision rate and 40% mortality rate.

Implant selection for HA operations vary with no universally accepted implant choice. The WHiTE3 trial suggested older designs such as the Thompson has equitable outcomes to more modern and expensive implants such as the Exeter V40+Unitrax.

Our multi-centre consecutive series of NOFs patients treated with HA assesses the impact of surgical and patient factors on dislocation risk.

Methods

Medical and radiographic records for patients treated between 1^stJanuary 2009 and 30^thSeptember 2017 with a HA at three acute hospitals were reviewed.

Implant and dislocation data were recorded. Patient demographics, comorbidities and operation details were extracted from the medical records and NHFD. Patients were excluded if there were no postoperative radiographs or when HA had been performed as a revision procedure.

Methods

Governance board approved retrospective study. 353 PAOs performed by the senior author between January 2014 and December 2017 were included. Exclusion criteria were inadequate pre-operative CT imaging and/or plain radiographs, previous pelvic/hip surgery, acetabular retroversion, or femoral head asphericity. Of the remainder, 84 had 3D analysis by clinical graphics giving measurements for CTFHC, LCEA at 1100, 1200, 1300 and sourcil angle (AI). XRLCEA, AI, posterior wall index (PWI), and anterior wall index (AWI), were measured from supine AP pelvis radiographs. Pearson correlation coefficient, and mean CTFHC for stratified LCEAs were calculated. A linear regression model to predict CTFHC from XRLCEA was validated against these.

Results

XRLCEA correlated very strongly with total femoral head coverage (Pearson=0.917, p<0.001). Mean CTFHC with XRLCEA between 15°-19.9° was 55% (range 51–59%). At 25° −29.9° mean CTFHC was 61%.

There was a linear relation of CTFHC with XR LCEA such that CTFHC = 41.5 + 0.78(XRLCEA). This linear regression model predicted CTFHC 55% (95%CI 54–56%) for XRLCEA of 17.5°, and CTFHC 63% (95%CI 62–64%) for XRLCEA 27.5°.

Introduction

Open and arthroscopic hip debridement may be used for treatment of femoral acetabular impingement (FAI). There is a paucity of evidence regarding the efficacy of one over the other.

Aim

To compare survivorship in terms of further surgical procedure at five years, in patients having undergone either arthroscopic or open hip debridement.

Background

National hip fracture programmes are becoming widespread, but this practice is nascent and varied. The Scottish Hip Fracture Audit (SHFA) was an early adopter of this strategy and is credited with substantial systemic improvements in quality and outcomes.

Objectives

To provide evidence and incentive to clinicians and administrators to adopt successful improvement strategies, and to facilitate data-driven change hip fracture care.

Background

This study aimed to investigate the effect of body mass index (BMI) on functional outcome following hip preservation surgery using the U.K. Non-Arthroplasty Hip Registry (NAHR).

Methods

Data on adult patients who underwent hip arthroscopy or periacetabular osteotomy (PAO) between January 2012 and December 2018 was extracted from the UK Non-Arthroplasty Hip Registry dataset allowing a minimum of 12 months follow-up. Data is collected via an online clinician and patient portal. Outcomes comprised EuroQol-5 Dimensions (EQ-5D) index and the International Hip Outcome Tool 12 (iHOT-12), preoperatively and at 6 and 12 months

Background

The purpose of this study was to report functional outcome scores following arthroscopic acetabular chondral procedures using the U.K. Non-Arthroplasty Hip Registry (NAHR).

Methods

Data on adult patients who underwent hip arthroscopy between January 2012 and December 2018 was extracted from the NAHR. Patients who underwent femoral sided chondral procedures were excluded. Patients who underwent osteophyte excision or a concurrent extra-articular procedure were also excluded. Cases were then classified according to the acetabular chondral procedure performed – ‘chondroplasty’, ‘microfracture’ or ‘none’ (no chondral procedure recorded). Outcomes comprised EuroQol-5 Dimensions (EQ-5D) index and the International Hip Outcome Tool 12 (iHOT-12), preoperatively and at 6 and 12 months.

Background

In a number of disciplines, positive correlations have been reported between volume and clinical outcome. This has helped drive the evolution of specialist centres to deal with complex or high risk medical conditions. Hip fractures are a common injury associated with high morbidity and mortality.

Aim

To assess whether volume of hip fracture cases attended to by individual hospitals is associated with the quality of care provided and clinical outcomes.

Background

Slipped capital femoral epiphysis (SCFE) creates a complex deformity of the hip that can result in cam type of femoroacetabular impingement (FAI), which may in turn lead to the early development of osteoarthritis of the hip. The purpose of this study was to evaluate the existing literature reporting on the efficacy of hip arthroscopic treatment of patients with FAI secondary to SCFE.

Methods

A systematic computer search was conducted based on the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines using Embase, PubMed (Medline), and Cochrane Library up to November 2019. Data such as patient demographics, surgical outcomes and complications that described arthroscopic surgery following FAI secondary to SCFE were retrieved from eligible studies. Two authors independently reviewed study inclusion and data extraction with independent verification.

Background

91% of blood loss in Total Hip Replacement (THR) occurs in the period after skin closure and the first 24 post-operative hours. TRAC-24 was established to identify if an additional 24-hour post-operative oral regime of Tranexamic acid (TXA) is superior to a once-only intravenous dose at surgery.

Methods

This was a prospective, phase IV, single centered, open label, parallel group controlled trial on patients undergoing primary elective THR. A history of thromboembolic or cardiovascular disease were not exclusion criteria. The primary outcome was indirect calculated blood loss at 48 hours (IBL). 534 patients were randomized on a 2:2:1 ratio over three different groups. Group 1 received an intravenous dose of TXA at the time of surgery and an additional 24-hour post-operative oral regime, Group 2 only received the intra-operative dose and Group 3 did not receive any TXA.

Aim

To assess the effect of different polyethylene modifications on Total Hip Replacement survival.

Methods

We combined the NJR dataset with polyethylene manufacturing properties as supplied by the manufacturers. Cause specific and overall reasons for revisions were analysed using Kaplan-Meier and multi-variate Cox proportional hazard regression survival analyses. Revision for aseptic loosening was the primary endpoint. Modification variables included resin type, radiation source, multiple cross-linking treatments, cross-linking dose, terminal sterilisation method, terminal sterilisation radiation dose, stabilisation treatment, total radiation dose, and packaging.

Overarching statements

These recommendations apply to post primary hip and knee replacement follow-up

The 10-year time point in these recommendations is based on a lack of robust evidence beyond ten years

The term complex cases refer to individual patient and surgical factors that may increase the risk for replacement failure

Introduction

Patients with reduced lumbar spine mobility are at higher risk of dislocation after THA as their hips have to compensate for spinal stiffness. Therefore our study aimed to 1) Define the optimal protocol for identifying patients with mobile hips and stiff lumbar spines and 2) Determine clinical and standing radiographic parameters predicting high hip and reduced lumbar spine mobility.

Methods

This prospective diagnostic cohort study followed 113 consecutive patients with end-stage hip osteoarthritis (OA) awaiting THA. Radiographic measurements were performed for the lumbar lordosis angle, pelvic tilt and pelvic-femoral angle on lateral radiographs in the standing, ‘relaxed-seated’ and ‘deep-seated’ (i.e. torso maximally leaning forward) position. A “hip user index” was calculated in order to quantify the contribution of the hip joint to the overall sagittal movement performed by the femur, pelvis and lumbar spine.

Background

Few studies have compared aspirin with DOACs (direct oral anticoagulants = direct thrombin inhibitors and factor Xa inhibitors) for venous thromboembolism (VTE) prophylaxis following total hip and knee replacement (THR and TKR). We assessed the efficacy and safety of aspirin compared with DOACs for VTE prophylaxis following THR and TKR using the world's largest joint replacement registry.

Methods

We studied the National Joint Registry linked to English hospital inpatient episodes for 218,650 THR and TKR patients. Patients receiving aspirin were matched separately to (1) direct thrombin inhibitors, and (2) factor Xa inhibitors using propensity scores. Outcomes assessed at 90 days included VTE, length of stay, and adverse events.

Aims

Our study aimed to 1) Describe the changes in spinopelvic mobility when transitioning from standing, to ‘relaxed-seated’ and thereafter to ‘deep-seated’ position and 2) Determine the change in spinopelvic mobility types 1 year post-THA compared to preoperatively.

Methods

This prospective diagnostic cohort study followed 100 consecutive patients 1 year post-THA. Preoperatively and one year postoperatively, radiographic measurements were performed for the lumbar-lordosis-angle, pelvic tilt and pelvic-femoral-angle on lateral radiographs in the standing, ‘relaxed-seated’ and ‘deep-seated’ position (torso maximally leaning forward). Patients were classified according to their spinopelvic mobility type, according to the change in PT between the standing and relaxed-seated position (stiff:ΔPT<±10°, normal:10°≤ΔPT≤30°, hypermobile:ΔPT>±30°).

Aims

The aim of this study was to conduct evidence synthesis on the available published literature of the impact of the training status of the operating surgeon (trainee vs. consultant) on the survival and revision rate of primary hip and knee replacements.

Patients and Methods

We conducted a systematic review according to Cochrane guidelines. Separate searches were performed for hip and knee replacements, with meta-analysis and presentation of results in parallel. We searched MEDLINE and Embase databases from inception to 17 September 2019 and included controlled trials and cohort studies reporting implant survival estimates, or revision rates of hip and knee replacements according to the grade of the operating surgeon. This study was registered with PROSPERO (CRD42019150494).

Introduction

Many worldwide regulatory authorities recommend regular surveillance of metal-on-metal hip arthroplasty patients given high failure rates. However concerns have been raised about whether such regular surveillance, which includes asymptomatic patients, is evidence-based and cost-effective. We determined: (1) the cost of implementing the 2015 MHRA surveillance in “at-risk” Birmingham Hip Resurfacing (BHR) patients, and (2) how many asymptomatic hips with adverse reactions to metal debris (ARMD) would have been missed if patients were not recalled.

Methods

All BHR patients subject to the 2015 MHRA recall (all females, and males with head sizes 46mm or below, regardless of symptoms) at one specialist centre were invited for review (707 hips). All patients were investigated (Oxford Hip Score, radiographs, blood metal ions, and targeted cross-sectional imaging) and managed accordingly. Surveillance costs were calculated using finance department data, as was the number needed to treat (NNT) to avoid missing one case of asymptomatic ARMD.

Introduction

Previous research has demonstrated increased early complication rates following total hip arthroplasty in obese patients, as defined by body mass index (BMI). Subcutaneous fat depth has been shown to be an independent risk factor for wound infection in cervical and lumbar spine surgery as well as after abdominal laparotomy. The aim of this study was to investigate whether increased peri-trochanteric fat depth was associated with increased risk of early complication following total hip arthroplasty.

Methods

We analysed prospectively collected data on a consecutive series of 1220 patients undergoing primary total hip arthroplasty from June 2013 until May 2018. The vertical soft tissue depth from the most prominent part of the greater trochanter to the skin was measured using a sterile ruler and recorded to the nearest millimetre. BMI was calculated at the patient's pre-operative assessment review. All complications (infection, dislocation and peri-prosthetic fracture) occuring within the initial 12 month follow-up were identified.

Aim

To assess the effect of the bearing surface and head size on the survival of total hip replacements with modern bearing surface combinations.

Methods

We combined the NJR dataset with polyethylene manufacturing properties as supplied by the manufacturers to sub-divide polyethylene into conventional (PE) and highly crosslinked (XLPE). Cause specific and overall reasons for revisions were analysed using Kaplan-Meier and multi-variate Cox proportional hazard regression survival analyses. The bearing surface analysis was repeated in patients undergoing THR under the age of 55.

Introduction

The achieved anteversion of uncemented stems is to a large extent limited by the internal anatomy of the bone. A better understanding of this has recently become an unmet need because of the increased use of uncemented stems.

We aimed to assess plan compliance in six degrees of freedom to evaluate the accuracy of PSI and guides for stem positioning in primary THAs.

Materials and Methods

We prospectively collected 3D plans generated from preoperative CTs of 30 consecutive THAs (17 left and 13 right hips), in 29 patients with OA, consisting of 16 males and 13 females (median age 68 years, range 46–83 years). A single CT-based planning system and cementless type of implant were used.

Post operatively, all patients had a CT scan which was reconstructed using state-of-the-art software solution: the plan and CT reconstruction models were

Outcome measures: 1) discrepancy between planned and achieved stem orientation angles Fig.2&3; 2) clinical outcome.

Aims

Urinary catheter use in the peri-operative and post-operative phase following arthroplasty may be associated with increased risk of urinary tract infection (UTI) and deep prosthetic joint infection (PJI). These can be catastrophic complications in joint arthroplasty. We performed a systematic review of the evidence on routine use of antibiotics for urinary catheter insertion and removal following arthroplasty.

Methods

Electronic databases were searched using the HDAS interface. Grey literature was also searched. From 219 citations, six studies were deemed eligible for review. Due to study heterogeneity a narrative approach was adopted. Methodological quality of each study was assessed using the CASP appraisal tool. Included studies were found to have moderate to good methodological quality.

Background

Reduced dislocation rates using lipped polyethylene (PE) liners in modular uncemented acetabular components has been shown, yet there may be increased wear because of impingement, which may lead to aseptic loosening. We used New Zealand Joint Registry (NZJR) data to compare survival rates, revision rates for dislocation and aseptic loosening between lipped and neutral liners.

Methods

31,247 primary THAs using the four commonly used uncemented modular cups were identified (January 1, 1999 to December 31, 2018). The lipped liner group comprised 49% males vs 42% in the neutral group (p < 0.001); 96% had OA vs 95% in the neutral group (p < 0.001). There was no difference in other patient characteristics. Mean follow-up was 5.1 years (SD 3.9); longest follow-up 19.3 years. Kaplan Meier survival rates were compared (20,240 lipped and 11,007 neutral PE liners). Highly cross-linked PE was used in 99% of lipped liner cups vs 85% of neutral liner cups. Associated hazard ratios were calculated using a Cox regression analysis.

INTRODUCTION

The capsular releasing sequence is crucial to safely conduct the Direct Anterior Approach for THA on a regular OR table. The release of the anterior capsule is the first step of the releasing sequence and allows for optimal exposure. This can be done by either resecting a part of the anterior capsule or by preserving it. Our zero hypothesis was that clinical outcomes would not be different between both techniques.

MATERIALS & METHODS

190 Patients operated between November 2017 and May 2018, met the inclusion criteria and were randomly allocated in a double blinded study to either the capsular resection (CR)(N=99) or capsular preservation (CP)(N=91) cohort. The same cementless implant was used in all cases. Patient-reported outcome measures (PROMS) were collected pre- and post-operatively at 6 weeks, 3 months and 1 year. Adverse events were recorded. Outcomes were compared with the Mann-Withney U test and a significance level of p<0,05.

Aims

Our study aimed to 1) determine if there was a difference for the HOOS-PS score between patients with stiff/normal/hypermobile spinopelvic mobility and 2) to investigate if functional sagittal cup orientation affected patient reported outcome 1 year post-THA.

Methods

This prospective diagnostic cohort study followed 100 consecutive patients having received unilateral THA for end-stage hip osteoarthritis. Pre- and 1-year postoperatively, patients underwent a standardized clinical examination, completed the HOOS-PS score and sagittal low-dose radiographs were acquired in the standing and relaxed-seated position. Radiographic measurements were performed for the lumbar-lordosis-angle, pelvic tilt (PT), pelvic-femoral-angle and cup ante-inclination. The HOOS-PS was compared between patients with stiff (ΔPT<±10°), normal (10°≤ΔPT≤30°) and hypermobile spinopelvic mobility (ΔPT>±30°).

INTRODUCTION

Quality monitoring is increasingly important to support and assure sustainability of the Orthopaedic practice. Many surgeons in a non-academic setting lack the resources to accurately monitor quality of care. Widespread use of electronic medical records (EMR) provides easier access to medical information and facilitates its analysis. However, manual review of EMRs is inefficient and costly. Artificial Intelligence (AI) software has allowed for development of automated search algorithms for extracting relevant complications from EMRs. We questioned whether an AI supported algorithm could be used to provide accurate feedback on the quality of care following Total Hip Arthroplasty (THA) in a high-volume, non-academic setting.

METHODS

532 Consecutive patients underwent 613 THA between January 1^st and December 31^st, 2017. Patients were prospectively followed pre-op, 6 weeks, 3 months and 1 year. They were seen by the surgeon who created clinical notes and reported every adverse event. A random derivation cohort (100 patients, 115 hips) was used to determine accuracy. The algorithm was compared to manual extraction to validate performance in raw data extraction. The full cohort (532 patients, 613 hips) was used to determine its recall, precision and F-value.

Aims

The aims of the study were to determine the differences in spinopelvic mobility between a cohort of hip OA patients and a control group for the 1) standing to relaxed-seated and 2) standing to deep-seated task.

Methods

A cohort of 40 patients with end-stage hip OA and a control group of 40 subjects, matched for age, gender and BMI were prospectively studied. Clinical data and lateral view radiographs in different positions were assessed. Sagittal spinopelvic mobility was calculated as the change when moving from the standing to relaxed-seated and standing to deep-seated positions for the lumbar lordosis angle, pelvic tilt and pelvic-femoral angle.

Background

Over 30 million people run marathons annually. The impact of marathon running on hips is unclear with existing literature being extremely limited (only one study of 8 runners).

Aim and Objectives

We aimed to better understand the effect of marathon running on the pelvis and hip joints by designing the largest MRI study of asymptomatic volunteers. The objectives were to evaluate the pelvis and both hip joints before and after a marathon.

Background

Orthopaedic surgeons are exposed to high levels of noise when performing common surgical procedures. Noise induced hearing loss (NIHL) has been demonstrated amongst senior orthopaedic staff. The objective of this study was to investigate the prevalence of hearing loss amongst arthroplasty surgeons compared to non-surgical clinicians and explore the factors associated with hearing loss.

Methods

A cross-sectional prevalence study. Arthroplasty surgeons and non-surgical clinicians were recruited from orthopaedic and medical conferences.

All participants were given a paper questionnaire including demographic details, hearing history and Tinnitus and Hearing Survey (THS). All participants were screened for hearing loss in a quiet room using the HearCheck Screener™ (Siemens, UK).

Logistic regression was used to identify factors associated with hearing loss. All statistical models were adjusted for age, gender, smoking status and personal noise exposure. A power calculation estimated a sample size of 100 participants.

Background

Total hip replacement (THR) is clinically and cost-effective. The surgical approach influences outcomes, however there is little generalisable and robust evidence to guide practice. We assessed the effect of surgical approach on THR outcomes.

Methods

723,904 primary THRs captured in the National Joint Registry, linked to hospital inpatient, mortality and patient reported outcome measures (PROMs) data with up to 13.75 years follow-up were analysed. There were seven surgical approach groups: conventional posterior, lateral, anterior and trans-trochanteric groups and minimally invasive posterior, lateral and anterior. Survival methods were used to compare revision rates and 90-day mortality. Groups were compared using Cox proportional hazards and Flexible Parametric Survival Modelling (FPM). Confounders included age at surgery, sex, risk group (indications additional to osteoarthritis), ASA grade, THR fixation, thromboprophylaxis, anaesthetic, body mass index (BMI), and deprivation. PROMs were analysed with regression modelling or non-parametric methods.

Introduction

Prosthetic joint infection (PJI) is the leading cause of failure of primary and revision hip and knee arthroplasty. It is challenging condition which represents a growing burden on hospital resources. In-patient hospital stay for antibiotic therapy post-operatively is costly and access to out-patient IV therapy (OPAT) varies between regions. In a tertiary referral centre for revision and infection, the suitability and cost-effectiveness of Dalbavancin was reviewed as a “single-shot” therapy following DAIR or revision lower limb arthroplasty for PJI.

Methods & Materials

A prospective service evaluation was carried out for consecutive patients treated for PJI of the hip or knee who received Dalbavancin. Treatment was indicated by Consultant Microbiologist advice within an MDT setting where clinical or patient factors made alternative therapies eg. OPAT inappropriate. Service-level data was collected to allow calculation of bed-day savings compared to a traditional 14-day course of IV treatment. Readmission rates to the trust within 30 days were reviewed as a marker of clinical efficacy and safety.

Purpose

Spinopelvic parameters are associated with the development of symptomatic femoroacetabular impingement and subsequent osteoarthritis. Pelvic incidence (PI) characterizes the sagittal profile of the pelvis and is important in the regulation of both lumbar lordosis and pelvic orientation (i.e. tilt). The purpose of this imaging-based study was to test the association between PI and acetabular morphology.

Methods

Measurements of the pelvis and acetabulum were performed for 96 control patients and 29 hip dysplasia patients using 3D-computed topography (3D-CT) scans. Using previously validated measurements the articular cartilage and cotyloid fossa area of the acetabulum, functional acetabular version/inclination, acetabular depth, pelvic tilt, sacral slope, and PI were calculated. Non-parametric statistical tests were used; significance was set at p<0.05.

Results

CT scans with 3D reconstruction of the existing cement mantle is possible using Modern CT with MARS protocols. After the training on sawbones and cadaveric bones a predictable plug perforation was obtained in all clinical cases. There were no intraoperative cortex perforations and no intraoperative femoral fractures.

Conclusion

CT scan analysis of femoral cement mantles together with patient specific drill guides are promising tools to reduce the risk of femoral perforation in revision total hip arthroplasty.

Background

One of the potential complications of polyethylene liner (PL) is its dissociation from the metal shell. This is a rare but catastrophic complication of total hip replacement (THR).

Objective

was to analyze the retrieved dissociated components (PL and shell) (Depuy Pinnacle, Warsaw, IN, USA) to evaluate the mechanism of failure. All these components were dissociated within four years of implantation.

Design and methods

Conducted at a quaternary referral centre for PJIs from Jan 2017 to July 2019. Suspected PJIs who underwent aspiration, incubated 14 days and later surgical intervention with minimum three tissue samples were included.

Results

176 aspirates were included. This is an increased number compared to our historic figures (average 88 Vs 48 pts/yr).

47 patients had fluid and tissue positive (true positive), 20 fluid +ive but tissue -ive (false positive), 98 fluid and tissue -ive (true negative) and 15 fluid negative but tissue +ive (False negative). Thus, sensitivity 76%, specificity 83%, positive predictive value70% and negative predictive value 87%.

Of 88 positive aspirates, only 75% were within 7-day cultures. Low virulence organisms as Propionibacterium acnes and coagulase negative staph were grown later.

Of 48 with only one tissue sample positive, 38 were culture-negative on aspiration and 6 grew different organisms on aspirate and tissues. Also, as many were cultured later, it suggests contamination.