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Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 128 - 128
1 Sep 2012
Espié A Espié A Laffosse J Abid A De Gauzy JS
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Introduction

Sternoclavicular dislocations are well-known adult injuries. The same traumatism causes growth-plate fracture of the medial clavicle in children and young adults. At this location, the emergence of the secondary ossification center and its bony fusion are late. We report the results of 20 cases hospitalized in the Toulouse University Hospital Center that were treated surgically.

Materials & Methods

20 patients were treated between 1993 and 2007, 17 boys and 3 girls, 16 years old (6–20). The traumatism was always violent (rugby 75%). Two physeal fractures were anteriorly displaced, and 18 posteriorly. The follow-up is 64 month (8–174).

Clinical, radiographic and therapeutic characteristics were assessed. The long-term results were analysed with: an algo-functional scale (Oxford shoulder score), the subjective Constant score, a functional disability scale (Shoulder simple test), a quality of life scale (DASH), and global indicators (SANE and global satisfaction).


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 586 - 586
1 Nov 2011
Diwanji S Laffosse J Lavigne M Vendittoli P
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Purpose: Even with modern ancillary and good surgical experience, rotational implant positioning is sometimes sub-optimal, leading to poor results. Except for obvious cases with patellar instability, the symptoms are often vague and non-contributive to the diagnosis of failure. This is why implant malpositioning and particularly malrotational postioning remain an underestimated cause of failure after primary total knee arthroplasty (TKA). We report our experience with TKA revision for rotational malpositioning.

Method: We retrospectively assessed the results of TKA revisions in 22 knees for malrotational positioning. In all cases, malrotational implant positioning was confirmed by CT-scan according to Berger’s protocol.

Results: Mean age was 66 years (47–74) at the time of the primary TKA. After the index procedure, all patients presented early anterior knee pain with patellar instability (tilt and subluxation in ten cases, and permanent patellar dislocation in two cases). Malrotational positioning predominated on the tibial component with mean 23° internal rotation. Mean cumulative malrotation (tibial plus femur) was 22° internal rotation. All but four patients underwent femoral and tibial component revision. In two cases, only the tibial component was revised, and in two other cases, isolated transposition of the anterior tibial tuberosity was carried out. One was a failure, and finally underwent a successful full revision. At a mean follow-up of 30 months (12–60), we noted significant functional outcome improvement. One patient, who underwent a patellectomy previously at the index TKA procedure, had persistant anterior knee pain. No patient presented patellar instability.

Conclusion: The diagnosis of implant malrotational positioning is sometimes difficult. The most common errors are tibial component positioning. In case of suspicion of malrotational positioning, protocolized CT-scan allows quick and simple diagnosis. If the malrotation is confirmed, TKA revision should be performed upon patient disability and severity of the symptoms. It is important not to delay the surgery, particularly in cases of patellofemoral dislocation because of the risks of developing soft tissue contractures resulting in a more difficult revision procedure.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 576 - 576
1 Nov 2011
Nzocou A Laffosse J Roy A Lavigne M Vendittoli P
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Purpose: Massive cavitary and segmental bone defects of the medial wall in revision arthroplasty are usually managed with large auto and/or allograft in association with a cemented or a cementless cup. To obtain a satisfactory hip center reconstruction with such a procedure can be sometimes challenging and the complications rate can be high. One other option is the use of a cup with a medial expansion (“protrusio cup”) to treat the medial bone defect.

Method: We carried out a retrospective study including 21 consecutive acetabular revisions arthroplasties using a cementless Converge Protrusio™ cup (Zimmer, Warsaw, IN, USA). Clinical outcomes were assessed by Harris Hip Score (HHS), WOMAC index and SF-12. Hip centre was assessed on anteroposterior (AP) view and the reconstruction was considered as satisfying when its location was located from − 10 to + 10 mm proximally (y axis) and/or medially (x axis) in comparison with ideal theoretical hip center location. Cup migration and modification of abduction angle were considered as significant when there were respectively > 4mm and to > 4° in comparison with the immediate postoperative AP view.

Results: At the last follow up [radiological data: 71.6 months (24–128.3) and clinical data: 72.1 months (24–129.5)], two patients were died and there were no lost of follow up. The mean HHS was 79.4% (52–100), WOMAC 82% (46–100), SF-12 52 (23–71) and 44 (18–65). Bone defect were filled with cancellous bone chips allograft in 16 cases and bulk bone allograft was used in only two cases to manage a large segmental defect of the roof. Bone graft integration was completed in all cases. The mean abduction cup angle was 43.6° (32–60). A satisfying hip centre positioning was obtained in 19 cases on x axis and in 10 cases on y axis, in all the remaining cases, we noted an improved implant positioning. The complications were: recurrent dislocation in one case (successfully revised with a constrained liner), infection in two cases (1 treated conservatively and the other one revised in two times procedure) and Brooker’s type III and IV ectopic ossifications in three cases. A significant cup migration occurred in only one case at nine years but was not revised because of painless. No case required revision for aseptic loosening.

Conclusion: Protusio cups appear as a reliable procedure to manage bone loss in acetabular revision. The revision procedure is widely simplified by reducing the use of the massive allograft and by promoting a satisfying hip center reconstruction to allow an optimal biomechanical joint functioning. Moreover, the cementless fixation in contact with patient acetabular bone makes more easy bone integration.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 522 - 522
1 Nov 2011
Lavigne M Therrien M Nantel J Prince F Laffosse J Girard J Vendittoli P
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Purpose of the study: The purpose of this work was to compare the subjective and functional outcomes of patients with a large diameter total hip arthroplasty (LD-THA) or hip resurfacing (HR).

Material and methods: Forty-eight persons were assessed and double blind randomised to receive either LD-THA (n=24) or HR (n=24). The clinical and radiographic assessment and gait analysis were performed preoperatively and at three, six and 12 months postoperatively. Gait analysis was performed once in a third group of healthy adults (n=14) who served as controls.

Results: The two groups were comparable preoperatively regarding demongraphic and functional characteristics. Postoperatively, the two groups with prostheses exhibited very rapid recovery with normalization of test results compared with controls within three to six months. The clinical assessment, the analysis of postural balance, gait analysis and most of the specific tests were not different between the two groups with prostheses.

Conclusion: There was no remarkable difference in subjective or objective assessments between subjects with a LD-THA or HR. This suggests that the only potential advantage of HR is the preservation of femoral bone stock. Long-term HR implant survival will determine the reality of this benefit.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 518 - 518
1 Nov 2011
Laffosse J Potapov A Malo M Lavigne M Fallaha M Girard J Vendittoli P
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Purpose of the study: A medial incision for implantation of a total knee arthroplasty (TKA) offers an excellent surgical exposure while minimising the length of the skin opening. This incision however implies section of the proximal portion of the infrapatellar branch of the medial saphenous nerve, potentially associated with lateral hypoesthesia and formation of a neuroma (painful scar). We hypothesised that an anterolateral skin incision would produce less hypoesthesia and postoperative discomfort.

Material and methods: We conducted a prospective randomised study to compare the degree of hypoesthesia after a medial or lateral skin incision for the implantation of a TKA. Fifty-knees in 43 patients, mean age 65.9±8.4 years were included; 26 knees for the lateral incision and 24 for the medial. All patients had the same type of implant. Clinical results were assessed with WOMAC, KOOS and SF36. Semme-Weinstein monofilaments were applied to measure sensitivity at 13 characteristic points. Patients were assessed at six weeks and six months. The zone of hypoesthesia was delimited and photographed for measurement with Mesurim Pro9®. Satisfaction with the surgery and the scar was noted. Data were processed with Statview®; p< 0.05 was considered significant.

Results: The two groups were comparable preoperatively regarding age, gender, body weight, height, body mass index, body surface area, aetiology, and clinical score. Operative time, blood loss, and number of complications were comparable. The functional outcomes (WOMAC, KOOS, SF36) were comparable at six weeks and six months. Active flexion was significantly greater at six months in the lateral incision group (p=0.03). The zone of hypoesthesia was significantly smaller in the lateral incision group at six weeks (p< 0.01) and at six months (p< 0.01), as were the number of points not perceived on the filament test (p< 0.01 in both cases) while the length of the incision was comparable (p> 0.05). This was associated subjectively, with less loss of sensitivity and less anterior pain reported by the patient at six months.

Discussion: Lateral and medial incisions enable comparable functional outcomes. The lateral incision produces less hypoesthesia and less anterior pain. This improves the immediate postoperative period and facilitates rehabilitation as is shown by the gain in flexion at six months.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 523 - 523
1 Nov 2011
Lavigne M Laffosse J Belzile E Morin F Roy A Girard J Vendittoli P
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Purpose of the study: Tribology studies of total hip arthroplasty (THA) have demonstrated that large diameter head in metal-on-metal bearings produce fewer wear particles than small diameter heads. The other advantages of this option are better stability, less dislocation, and optimal joint range of motion. The purpose of this work was to compare blood levels of chromium, cobalt and titanium six months and one year after implantation of different models of large diameter metal-on-metal THA.

Material and methods: We conducted a retrospective comparative and randomised study including 110 patients who had been implanted with a larger diameter head THA/Zimmer? Smith and Nephez, Biomet or Depuy. The metal ion concentrations (Cr, Co, Ti) were measured in whole blood by an independent laboratory using high-resolution mass spectrometry (HR-ICP-MS). Blood samples were drawn preoperatively and postoperatively at six months and one year.

Results: At six months, the concentrations of metal ions in whole blood expressed as mean (range) for Cr (μg/L) Co (μg/L) and Ti (μg/L) were, respectively: Zimmer 1.3 (0.4/2.8) 1.7 (0.9/6.8) 2.5 (0.6/6.7); Smith and Nephew 2.0 (0.7/4.2) 2.1 (0.5/6.6) 1.1 (0.5/4.1); Biomet 1.2 (0.4/2.2) 0.9 (0.3/3.4) 1.4 (0.8/2.4); Depuy 1.7 (0.5/3.2) 1.9 (0.3/4.2) 1.3 (0.5/3.9). There was a significant difference between groups for Cr (p=0.006), Co (p=0.047) and Ti (p< 0.001). The Biomet implants presented the lowest concentrations for Cr and Co; the Zimmer implants gave the highest levels of Ti.

Discussion and Conclusion: Several implant-related factors affect blood concentrations of metal ions: contact surfaces leading to “active” abrasion but also wear in other parts of the implant giving rise to “passive” corrosion. Bearing wear is related to the diameter of the head, its roughness, its spherical shape, joint clearance, the manufacturing technique (forging, casting) and its carbon content. The Biomet head corresponds to a better compromise for these different factors. Passive corrosion can result from an exposed metal surface or from metal to metal contact. This explains the high level of Ti ions found for all implants tested since titanium is not present in the bearings.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 542 - 542
1 Nov 2011
Dao C Laffosse J Bensafi H Tricoire J Chiron P Puget J
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Purpose of the study: We report the clinical and radiographic results of a series of revision total hip arthroplasties performed for aseptic loosening using a non-demented modular femoral implant (PP).

Material and methods: From 1991 to 2003, 146 revisions of total hip arthroplasty were performed using the same non-cemented modular femoral implant (PP). At mean nine years follow-up (3.5–17 years), 24 patients had died, 26 had insufficient data for review and 39 were lost to follow-up. The analysis thus included 54 cases. All revisions were performed for aseptic loosening. Mean age at surgery was 60 years. Preoperative bone damage, according to the Sofcot classification, was grade I and II (69%), grade III (26%), grade IV (5.5%). Clinical outcome was assessed with the Harris and Postel-Merle-d’Aubigné scores. The radiological review analysed stem anchoring, lucency and periprosthetic reconstruction.

Results: At mean nine years follow-up, the mean Harris score was 71 points, the mean PMA score 12.8 points. Patient satisfaction was 70%. There were five cases with deep infection (9%), five with dislocation and six intra-operative periprosthetic fractures. Trochanterotomy non-union was noted in 26% of patients. Mean impaction of the femoral stem was 5 mm (range 0–16 mm). There was a statistically significant association between the degree of bone damage and the quality of the bone reconstruction (p=0.012). Mean increase in cortical thickness in zones 1 and 2 (Gruen) was 1.1 mm and 1.6 mm respectively. In Gruen zones 2 and 6, the gain was 6 and 10 mm respectively. There were nine surgical revisions (17%) for deep infection (n=4), recurrent aseptic loosening and fracture of the femoral implant (n=1). The ten-year survival taking aseptic loosening as the endpoint was 90%.0

Discussion and Conclusion: Our work showed the good long-term results obtained with this implant for revision total hip arthroplasty. It allows clinical improvement, periprosthetic bone reconstruction and a low rate of surgical revision.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 497 - 498
1 Nov 2011
Chiron P Laffosse J Loïc-Paumier F Bonnevialle N
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Purpose of the study: Transadductor approaches to the hip joint have been described in the spastic child. Ludl-off as well as Ferguson pass behind the short adductor and the pectineus, a narrow route with a risk of injuring the obturator nerve. We describe a simple minimally invasive approach.

Material and method: The incision is made with the hip in the flexion, external rotation, abduction, from the pubic insertion of the long adductor following along the mass of the muscle for 6 to 8 cm. The aponeurosis of the long adductor is cut just deep enough to see the muscle fibres. Careful finger dissection of the muscle sheath common to the three anterior adductor muscles leads directly to the lesser trochanter. Two forceps are inserted on either side of the lesser trochanter, exposing the lesser trochanter and the tendon of the iliopsoas muscle. Dissection of the iliopsoas muscle held aside (follow the tendon on its lateral aspect leading to the vessels). An angled spreader is positioned between the anterior aspect of the capsule and the medial border of the tendon, displacing the tendon laterally and exposing the capsule. Extra-articular exposure of the capsule with a rugine to displace the posterior medial circumflex pedicle. Longitudinal incision of the capsule continued along the inter-trochanteric line to the peri-acetabular region. The medial as well as the anterior aspect of the neck can be visualized by rotating the hip. The inferior and anterior portion of the head is visible: the iliopubic branch and the entire superior and medial wall of the acetabulum can be exposed.

Results: We performed 29 medial approaches. Nine for periprostheic pain, four for fresh fracture of the femoral head during posterior dislocation, four for old fractures of the femoral head during posterior dislocation, three for chondromatosis, three for tumours of the femoral head or the acetabulum, six for retractile periarthritis without arthroplasty. Hip arthroplasty (7) or not (6), median pain could be induced by the presence of retractile periarthritis with presence of synovial adherences to the femoral neck penetrating into the joint space; release relieved pain in 11/13.

Conclusion: The medial approach to the hip joint is a useful orthopaedic technique with a rapid learning curve.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 576 - 576
1 Nov 2011
Diwanji S Laffosse J Aubin K Lavigne M Vendittoli P
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Purpose: Femoral neck narrowing (FNN) has been reported after metal-on-metal hip resurfacing (HR). It is significant (> 10%) in a number of cases (from 0 up to 27.6%). Its origin remains unclear, but bone remodelling, impingement, head necrosis and osteolysis have been incriminated. The aims of this study were to assess these issues and describe their consequences in a prospective series with a minimum follow-up of five years.

Method: Fifty-seven HRs in 53 patients (30 men, 23 women, average age 49.2±8.4 years) were included prospectively with clinical (WOMAC, UCLA activity score) and radiological evaluation at one, two and five years. All patients received the Durom™ resurfacing system (Zimmer, Warsaw, IN, USA), with cementless acetabular cup and cemented femoral implant. All cases were undertaken via a posterior approach. Femoral and acetabular implant positioning was assessed. The neck-to-head prosthesis (N/H) ratio was calculated at the junction of the neck with the femoral component and at mid-distance between the neck junction and the inter-trochanteric line (N1/2/H) on anterior-posterior view. Ion concentrations (chromium, cobalt and titanium) were measured at 12 months. We considered p< 0.05 as the significance level.

Results: The N/H ratio decreased significantly at one, two and five years in comparison to the postoperative data (p< 0.01 for all parameters) and N1/2/H declined significantly only at one and two years (p=0.003 and p=0.03, respectively). There was no difference in the N/H ratio or N1/2/H between two and five years. We encountered no deleterious consequences of FNN on clinical outcome, and no significant relationship with cup positioning, gender, body mass index or level of activity. Femoral positioning in valgus was associated with a decrease in N1/2/H at one and two years (p=0.02), whereas the N/ H ratio tended to be lower when cobalt concentration was elevated (p=0.08). Significant FNN was observed in two cases at two years (−12.9% and – 11.1%) with a localized and progressive femoral anterior-superior notch absent on immediate postoperative X-rays. At five years, we noted three other cases with circumferential FNN, limited at the junction neck-cup area (average narrowing around – 20% between two and five years). One of these cases presented a femoral stem fracture. Osteonecrosis was confirmed during surgical revision.

Conclusion: In the current group, FNN was seen infrequently up to five years after surgery (9%). Mechanically-induced remodelling should be differentiated from overall FNN which may be due to femoral head necrosis. In this case, revision could be proposed before implant failure or femoral loosening. Impingement causes very early and localized FNN at the upper part of the neck; for these patients, simple observation should be the rule, all the more since they are usually pain-free and rarely disabled.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 499 - 499
1 Nov 2011
Molinier F Tricoire J Laffosse J Bensafi H Chiron P Puget J
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Purpose of the study: Correct implant position is one of the factors of long-term success of total hip arthroplasty (THA). Acetabular architectural defects caused by trauma can create difficult situations leading to potential complications and poor outcome. The purpose of this study was to examine retrospectively the results of THA implanted after fracture of the acetabulum treated surgically. The objective was to analyse the specific features and search for factors favouring poor outcome.

Material and method: The series included 43 patients who had a THA implanted after treatment of an acetabular fracture. Mean age at trauma was 44.5 years (range 16–87). Five patients had a THA immediately, mean age 75 years (63–87). Thirty eight patients had osteosynthesis. According to the Letournel classification, the fracture was elementary in 12 cases and complex in 26. In ten patients, there was residual joint incongruence measuring more than 2 mm after osteosynthesis. The hips evolved to degenerated joint (n=34) and or necrosis (n=10).

Results: Mean time from acetabular osteosynthesis to THA was 94.6 months (range 3–444), excluding those patients whose THA was implanted at the time of the osteosynthesis. Arthroplasty required removal of the osteosynthesis material (n=11), insertion of a supportive ring (n=14) associated with a bone graft (n=13). The acetabular implant was considered to be well positioned according to the Pierchon criteria in 16 hips and was lateralised (n=21) and/or ascended (n=17) in the other hips. Inclination was 42.8 on average, range 10–18. The five-year survival was 80%.

Discussion: Arthroplasty after surgical treatment of an acetabular fracture is a difficult procedure. Complementary procedures are often necessary complicating the surgery and increasing the risk of perioperative complications, particularly infection. It is difficult to position the acetabular implant, increasing the risk of postoperative instability and early loosening. This study demonstrated the difficulties of implanting a THA in this context where the revision rate is significantly higher than in first-intention THA.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 565 - 565
1 Nov 2011
Potapov A Vendittoli P Laffosse J Lavigne M Fallaha M Malo M
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Purpose: Antero-medial parapatellar skin incision in total knee arthroplasty (TKA) provides excellent surgical exposure with minimal skin incision length. However, it is associated with the infrapatellar branch of the saphenous nerve section, leading to antero-lateral knee hypoesthesia and sometimes painful nevroma. We hypothesized that

antero-lateral skin incision in TKA produces a lower rate of hypoesthesia compared to the medial parapatellar cutaneous approach, and

reduced hypoesthesia is linked with less discomfort and possibly a better clinical outcome.

Method: A total of 69 knees in 64 patients who underwent TKA were randomized for antero-medial (n=35) or antero-lateral (n=34) skin incision. Mean age was 66.4±8.2 years. Functional outcome was assessed by WOMAC, KOOS and SF-36 scores pre-operatively and at six weeks, six months and one year follow-up. Range of motion (active and passive flexion and extension) was measured. The area of hypoesthesia was analyzed in a standardized manner by an independent observer using a calibrated Semme-Weinstein monofilament applied on 13 reference points. A digital photograph was taken, and the area of hypoesthesia was then measured informatically (Mesurim Pro® software). Patient satisfaction with their scar and their surgery was evaluated. Statistical analysis was carried out with p< 0.05 considered as significant.

Results: The two groups were comparable pre-operatively. There was no significant difference in functional outcome (WOMAC, KOOS, SF-36 scores) at six weeks, six months and one year between the two groups. Active and passive ranges of motion were comparable. The area of hypoesthesia and the number of non-perceived points in the monofilament test were significantly lower after antero-lateral incision at six weeks (p=0.007 and p=0.02, respectively) and 6 months (p=0.02 and p=0.005, respectively). At one year, the area of hypoesthesia was lower in the antero-lateral group, but was not significant (p=0.08). Antero-lateral incision patients reported a lower rate of subjective sensitivity loss and anterior knee pain at six weeks, six months and one year.

Conclusion: Antero-medial and antero-lateral parapatellar skin incisions in TKA have a similar functional outcome. However, antero-lateral cutaneous incision produces a lower rate of hypoaesthesia and less anterior knee pain in the early recovery period.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 508 - 508
1 Nov 2011
Laffosse J Lavigne M Girard J Vendittoli P
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Purpose of the study: Despite a survival rate to the order of 90–95% at ten years, implant malposition and particularly malrotation can cause an underestimation of failure after total knee arthroplasty (TKA). We report our experience with revision TKA for isolated malrotation.

Material and methods: Twelve patients underwent revision for isolated maltrotation of an implant. This series of three men and nine women, mean age 66 years, range 47–74 years at primary surgery, were reviewed retrospectively. During the follow-up, all patients complained of early onset anterior knee pain, which was generally noted severe, associated with moderate patellar instability in four cases, noted severe in 7 others and extreme in one (permanent patellar dislocation). Half of the patients also exhibited hyperlaxity was invalidating instability. Range of motion was generally preserved (2/5/100). In all cases, the rotational problems were confirmed on the computed tomography which revealed predominant tibial malrotation, measured at 23 mean internal rotation and a cumulative malrotation (femur+tibia) of 22 internal rotation.

Results: All patients except two required revision of both femoral and tibial implants. In one case, the tibial piece was alone changed and in another, isolated translation of the anterior tibial tuberosity was performed. For eight of eleven cases, the revision implants had a stem and femoral inserts were used to control the bone stock loss induced by the corrective cuts in six cases and requiring more or less extensive ligament balance procedures in six. At mean follow-up (30 months, range 12–60), there was a very significant improvement in the functional results; only one patients with a history of patellectomy complained of persistent anterior pain. None of the patients complained of patellar instability.

Discussion: Excessive cumulative internal rotation of the implants induces increased stress on the patella, causing early anterior pain, then subluxation and finally dislocation beyond −15 to −20° internal rotation. These position errors are concentrated on the tibia were care must be taken to respect the anatomic landmarks (bicondylar axis, anterior tibial tuberosity) to avoid early failure. In the event of major rotational disorders, revision may be required with procedures to correct the ligament balance.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 223 - 223
1 May 2011
Vendittoli PA Amzica T Roy A Girard J Laffosse J Lavigne M
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Introduction: Metal on metal hip replacement using large diameter bearings can be used as part of a hip resurfacing (HR) system or with a large diameter head total hip arthroplasty (LDH-THA). Both types of implant release metal ion, but the amount of ion released after LDH-THA has not been studied. The aim of the present study was to assess whole blood metal ion release at one year following LDH-THA.

Material and Method: Pre and post operative Cr, Co and Ti concentrations in whole blood were measured using a high resolution mass spectrometer (HR-ICP-MS) in 29 patients with LDH-THA (Durom LDH, Zimmer). The results were compared to published ion levels on a HR system (Durom, Zimmer) possessing the same tribological characteristics, the only differences being the presence of a modular sleeve and opened femoral head design in LDH-THA.

Summary of results: Post operative Cr, Co and Ti mean levels of LDH-THA were 1.3, 2.0 and 2.8 μg/L at 6 months and 1.3, 2.2 and 2.7 μg/L at 12 months. In the LDH-THA, the opened femoral head design showed significantly higher Co ion concentrations than the closed femoral head design (3.0 vs 1.8 ug/L, p=0.037). Compared to previously published results after HR, Co levels were significantly higher at one year in the LDH THA (2.2 ug/L vs. 0.7 ug/L, p< 0.001).

Discussion: In order to reduce wear and ion release from metal-metal bearing, most manufacturers focus research on improvements at the bearing surfaces. This study has demonstrated that the addition of a sleeve with modular junctions and an open femoral head design of LDH-THA causes more Co release than bearing surface wear (157% and 67% respectively). Even if no pathological metal ion threshold level has been determined, efforts should be made to minimize their release. We recommend modification or abandonment of the modular junction and femoral head closed design for this specific LDH-THA system. The total amount of ion released from a metal-metal implant should be considered globally and newer implant design should be scientifically evaluated before their widespread clinical use.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 307 - 308
1 May 2010
Paumier F Laffosse J Chiron P Bensafi H Molinier F Puget J
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Purpose of the study: We conducted a retrospective study of 66 cases of non-traumatic osteonecrosis of the femoral head by percutaneous drilling and autograft. This technique associated drilling with graft conductor effects and bone marrow inducers.

Material and Methods: Forty-six patients (41 male, 5 female) with non-traumatic osteonecrosis were included in this study. Mean age at surgery was 46 years (22–68). The 66 cases involved 32 right hips and 34 left hips (21 bilateral cases), six asymptomatic. Osteonecrosis was related to corticosteroid therapy (n=17), chronic ethylism (n=14), dyslipidaemia (n=7), barotraumatism (n=3), and renal transplantation (n=1). Four were found idiopathic. The preoperative ARCO classification was: 8 stage IIA, 21 stage IIB, 15 stage IIC, 7 stage IIIB, 13 stage IIIC and 2 stage IV. A minimally invasive surgical technique combined simple percutaneous drilling with a cancellous iliac bone graft harvested percutaneously homolaterally. Metaphyseal grafts were excluded from this analysis. Minimum postoperative follow-up was two years. The main outcome was rate of prosthesis conversion at two years.

Results: Considering all stages, 38 hips did not have a total prosthesis at two years (58% success) with a mean follow-up of 40 months (25–65). Twenty-eight hips had total prosthesis at two years (42% failure) with mean follow-up of 11 months (3–23). Mean survival was 29 months (3–65) with stabilisation of the initial lesions in 50% of hips. For the 44 stage II hips, success was achieved in 28 (64%). The success rate for stages IIA and IIB was 70% with mean follow-up of 29 months (19–65). For the 20 stage III hips success was achieved in nine (45%), with 30% for stage IIIB and 54% for stage IIIB and mean follow-up of 21 months (12–45). There were no cases of mechanical complications. One superficial skin infection cured favourably.

Discusssion and conclusion: Subchondral fracture (stage III) and necrosis volume > 30% appear to be unfavourable factors for outcome with this technique. There are other conservative treatments but all with technical difficulties or cost considerations despite sometimes questionable results. This technique is simple and very attractive. In one hand, it combines the advantages of the decompression-effect for the local vascularization with the bone inducer effect of the marrow auto-graft. And in the other, it is a non-invasive and conservative procedure which does not modify the morphology of the upper extremity of the femur and does not jeopardize a future total hip replacement. This is a reliable technique which merits confirmation with a larger series. The best indication remains stage IIA and IIB.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 289 - 289
1 May 2010
Laffosse J Minville V Colombani A Gris C Chassery C Pourrut J Eychenne B Saami K Chiron P
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Purpose of the study: Earlier studies have demonstrated that the use of synthetic alpha-erythropoeitin can reduce the need for perioperative transfusions in orthopaedic surgery. The purpose of our study was to evaluate the effect of administering synthetic beta erythropoeitin (betaEPO) on the preoperative serum haemoglobin level in patients scheduled for total hip replacement (THR).

Material and Methods: Three groups of patients were studied. In the EPO group (15 patients) the haemoglobin level 30 days before surgery was 13 g/dl. If there were no contraindications, patients in this group were given a subcutaneous injection of betaEPO (Néorecormon® 30,000 units in prefilled syringes) four times (days -21, -14, -7, -1). In group C the haemoglobin level was greater than 13 g/dl and no betaEPO was administered. In the third group (control group), 42 patients had a serum haemoglobin level less than 13 g/dl but were not given betaEPO. The patients were not randomised. The serum haemoglobin level was measured the day before surgery (day -1), the day after surgery (day +1), and the fifth postoperative day (day +5). Data collected were body mass index (BMI), operative time, and number of blood transfusions (cell-saver, auto-, allo-transfusion). Total red cell loss was calculated thanks to a standardized method. P< 0.05 was considered significant.

Results: The three groups were comparable preoperatively for age, gender and BMI and operatively for operative time and blood loss. Haemoglobin level was significantly higher in group C and EPO at day -1 and day +1 compared with the control group. Increase in haemoglobin level was 2.76 g/dl in the EPO group versus 0.05 and 0.04 in group C and controls (p< 0.001). Significantly fewer patients were transfused in group EPO (7%) and group C (12%) compared with controls (60%, p< 0.001). Similarly fewer packed cell units transfused was required in groups C and EPO versus the controls. The duration of the hospital stay was shorter in group C than in group EPO, which in turn was shorter than for the control group (p=0.02).

Discusssion and conclusion: A low haemoglobin level preoperatively is a risk factor for perioperative transfusion in patients undergoing THR. Preoperative administration of beta EPO, by increasing the haemoglobin level just before surgery, significantly reduces the need for blood transfusions and thus reduces the risk of complications related to such transfusions. This method can also avoid the use of autotransfusions which can favour pre and postoperative anaemia. Broader indications in orthopaedic surgery or in traumatology for the use of EPO should be implemented in order to reduce the number of operated patients requiring transfusion.


The Journal of Bone & Joint Surgery British Volume
Vol. 92-B, Issue 1 | Pages 103 - 109
1 Jan 2010
Laffosse J Espié A Bonnevialle N Mansat P Tricoire J Bonnevialle P Chiron P Puget J

We retrospectively analysed the clinical results of 30 patients with injuries of the sternoclavicular joint at a minimum of 12 months’ follow-up. A closed reduction was attempted in 14 cases. It was successful in only five of ten dislocations, and failed in all four epiphyseal disruptions. A total of 25 patients underwent surgical reduction, in 18 cases in conjunction with a stabilisation procedure.

At a mean follow-up of 60 months, four patients were lost to follow-up. The functional results in the remainder were satisfactory, and 18 patients were able to resume their usual sports activity at the same level. There was no statistically significant difference between epiphyseal disruption and sternoclavicular dislocation (p > 0.05), but the functional scores (Simple Shoulder Test, Disability of Arm, Shoulder, Hand, and Constant scores) were better when an associated stabilisation procedure had been performed rather than reduction alone (p = 0.05, p = 0.04 and p = 0.07, respectively).

We recommend meticulous pre-operative clinical assessment with CT scans. In sternoclavicular dislocation managed within the first 48 hours and with no sign of mediastinal complication, a closed reduction can be attempted, although this was unsuccessful in half of our cases. A control CT scan is mandatory. In all other cases, and particularly if epiphyseal disruption is suspected, we recommend open reduction with a stabilisation procedure by costaclavicular cerclage or tenodesis. The use of a Kirschner wire should be avoided.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 68 - 68
1 Mar 2009
Laffosse J Chiron P Molinier F Bensafi H Puget J
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Introduction: The minimally invasive posterior approach has become a standard for total hip replacement (THR) but the interest for the other minimally invasive approaches has not waned in any way. We carried out a prospective and comparative study in order to analyse the interest of the anterolateral minimal invasive (ALMI) approach in comparaison to a minimally invasive posterior (MIP) approach for THR.

Material and method: We carried out a prospective and comparative study. A group of 35 primaries THR with large head using the ALMI approach, as described by Bertin and Röttinger, was compared to a group of 43 primaries THR performed through the MIP approach. The groups were not significantly different with respect to age, sex, bony mass index, ASA score, Charnley class, diagnoses and preoperative Womac index and PMA score. The preoperative Harris hip score was significantly lower in ALMI group. Early functional results have been evaluated thanks to Womac index and modified Harris hip score at 6 weeks, 3 and 6 months. A p value < 0.05 has been considered as significant.

Results: The duration of surgical procedure was longer and the calculated blood loss more important in ALMI group (respectively p=0.045 and p=0.07). The preoperative complications were significantly more frequent in this group with 4 greater trochanter fractures, 3 false routes, 1 calcar fracture, and 2 metal back bascules versus one femoral fracture in MIP group. Other postoperative data (implant positioning, morphine consumption, length of hospital stay, type of discharge) were comparable. The early functional results at 6 weeks, 3 and 6 months were also comparable. No other complication has been noted during the first 6 months in the two groups.

Discussion and Conclusion: The ALMI approach uses the intermuscular interval between the tensor fascia lata and the gluteus medius. It leaves intact the abductors muscles and the posterior capsule and short external rotators. The early clinical results are excellent despite of the initial complications related to the initial learning curve for this approach and the use of the large head with metal-on-metal bearing. The stability of the arthroplasty and the absence of muscular damage should permit to accelerate the postoperative rehabilitation in parallel with less preoperative complications after the initial learning curve.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 292 - 292
1 Jul 2008
BENSAFI H GIORDANO G LAFFOSSE J DAO C PAUMIER F JONES D TRICOIRE J MARTINEL V CHIRON P PUGET J
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Purpose of the study: Percutaneous compressive plating (PCCP) enables minimally invasive surgery using closed focus technique. We report a prospective consecutive series of 67 fractures (December 2003 – February 2005) followed to bone healing.

Material and methods: Mean patient age was 83 years (range 37–95) with 83% females in a frail population (ASA 3, 4). Two-thirds of the patients had unstable fractures (AO classification) which were reduced on an orthopedic table under fluoroscope. Two minimal incisions were used to insert the material without opening the fracture and without postoperative drainage. Blood loss was noted. Verticalization and weight bearing were encouraged early depending on the patient’s status but were never limited for mechanical reasons. Patients were reviewed at 2, 4 and 6 months.

Results: Anatomic reduction was achieved in 84% of hips, with screw position considered excellent for 45, good for 14, and poor for 6. There were no intraoperative complications. The material was left in place. The hemoglobin level fell 2.2 g on average. Mean operative time was 35 minutes and the duration of radiation exposure 60 seconds. Mean hospital stay was 13 days. General complications were: urinary tract infections (n=10), phlebitis (n=2), talar sores (n=5). Gliding occurred in three cases (4%) with telescopic displacement measuring less than 10 mm in ten cases. There were two varus alignments with no functional impact. There were four deaths within the first three weeks. All fractures healed within three months.

Discussion and conclusion: PCCP has its drawbacks (mechanical, stabilization) as do all osteosynthesis methods used for trochanteric fractures. The technique is reliable and reproducible and is indicated for all trochanteric fractures excepting the subtrochanteric form. PCCP has the advantage of a closed procedure with a minimal incision and limited blood loss for a short operative time. An advantage for this population of elderly frail subjects (ASA 3, 4). PCCP enables immediate treatment with a low rate of material disassembly compared with other techniques.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 107 - 107
1 Apr 2005
Tricoire J Laffosse J Nehme A Bensafi H Puget J
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Purpose: Improved surgical technique and facilities enable emergency salvage of very damaged limbs. Functional outcome after this type of conservative treatment is generally satisfactory but at the risk of more or less quiescent osteitis. In the event of chronic osteitis, the neighbouring skin can undergo malignant degeneration (squamous-cell carcinoma). The purpose of our work was to report three such transformations and discuss therapeutic indications.

Material and methods: The study series included three patients with chronic osteitis of the tibia after trauma. During surveillance, several years later we observed changes in local signs: increasing pain, purulent discharge and bleeding (Rowlands triad). In each patient, biopsy led to the diagnosis of transformation to squamous-cell carcinoma. All patients were treated by above knee amputation.

Results: Outcome was satisfactory with an excellent quality scar formation. The search for extension was still negative a three years follow-up.

Discussion: The frequency of carcinomatous degeneration near zones of chronic osteitis varies depending on the series to 0.2% to 1.7%. This is in sort the cost of conservative treatment. Changes in the clinical presentation, Rowland’s triad, associated with modification of the bacterial flora and development of a nauseous odour are important signs which should be followed by a biopsy. The treatment of choice for most authors is amputation in order to increase patient survival.

Conclusion: The desire to pursue conservative reconstruction surgery even in the most difficult cases should not mask the risk of potential malignant transformation. Secondary amputation should not be considered as a failure in these extreme clinical situations.