Introduction. Accurate component placement in total hip arthroplasty (THA) improves post-operative stability and reduces wear and aseptic loosening. Methods for achieving accurate stem placement have not been as extensively studied as cup placement. Objectives. The purpose of this study is to determine how consistently femoral stem version can be corrected to an ideal of 15 +/− 5 degrees using robotic guidance. Furthermore, the study aims to identify other factors related to approach and patient demographics, which may influence the degree of correction obtained. Methods. 175 consecutive patients who underwent MAKO robotic guidance THA were included in the study with a mean age of 57.9 years and a mean body mass index (BMI) of 30.41kg/m2. 48% of the population was male and 74% of the procedures were performed through an anterior approach. The absolute difference between 15 degrees of anteversion and native femoral version as well as 15 degrees of anteversion and femoral stem version was calculated for each patient. A smaller absolute value post-operatively reflects a closer femoral stem version to a target of 15 degrees. Results. The mean native femoral version was 6.39+/−9.14 degrees. The mean stem version was 9.23+/−8.57 degrees. With respect to achieving a target version of 15 degrees the mean absolute difference between native version and 15 degrees was 10.46+/−6.94 degrees and mean absolute difference between the stem version and 15 degrees was 8.37+/−6.03 degrees. This difference was statistically significant. 69% of patients were able to have their native femoral version corrected to a target of 15 degrees. Conclusions. Robotic guidance in THA was effective in correcting native femoral version towards a target of 15 degrees. This is can be achieved using both the anterior and posterior approach and is not affected by BMI

Introduction

Appropriate prosthetic alignment is an important factor in maintaining stability and maximising the performance of the bearing after total hip replacement (THR). With a cementless component, the anteversion of the native femur has been shown to influence the anteversion of the prosthetic stem. However, the extent to which anteversion of a cementless stem can be adjusted from the native anteversion has seldom been reported. The aim of this study was to investigate the difference between native and stem anteversion with two different cementless stem designs.

Background. Virtual planning of shoulder arthroplasty has gained recent popularity. Combined with patients specific instrumentation, several systems have been developed that allow the surgeon to accurately appreciate and correct glenoid deformities in version and inclination. While each virtual software platform utilizes a consistent algorithm for calculating these measurements, it is imperative for the surgeon to recognize any differences that may exist amongst software platforms and characterize any variability. Methods. A case-control study of all CT scans of patients previously pre-operatively planned using MatchPoint SurgiCase® software were uploaded into the BluePrint software. The cohort represents surgical planning for total shoulder arthroplasty and reverse shoulder arthroplasty with varying degrees of glenoid deformity. Glenoid version and inclination will be recorded for each CT scan using both software platforms. Results. A total of 38 patient CT scans previously planned using MatchPoint Surgicase® software were uploaded into the BluePrint software. The mean difference for glenoid version between the two software programs was 2.497° (±1.724°) with no significant differences in measured glenoid version readings between BluePrint and SurgiCase software (p=0.8127). No significant differences were seen in the measured glenoid inclination between the two software programs (p=0.733), with a mean difference for glenoid inclination between the two software programs at 5.150° ± 3.733° (figure 1). A Bland-Altman plot determined the 95% limits of agreement between the two programs at −5.879 to 6.116 degrees of glenoid version and −12.05 to 12.75 degrees of glenoid inclination. There was a significant statistical agreement between the two software programs measuring glenoid version and inclination in relation to glenoid wear position for the centered (p=0.004), posterior (p<0.001, p=0.003), posterior-superior (p<0.001, p<0.001), and superior (p=0.027, p=0.034) positions, respectively. Conclusions. Both BluePrint and SurgiCase software platforms yield similar measurements for glenoid version and glenoid inclination. In the setting of glenoid wear in the posterior, posterior-superior or superior position, measurements of between two surgical platforms are in agreement

Purpose. Glenoid version has been correlated with tears within the rotator cuff. Cuff tear arthropathy is an evolution of multiple unhealed tendons ultimately resulting in pseudoparalysis. Although several factors are critical to allow tendon healing, we have observed that there is less glenoid version in patients with cuff tear arthropathy. This was compared to those with osteoarthritis where rotator cuff tears are uncommon. We hypothesize that patients undergoing inverse prosthesis generally have a near neutral glenoid. Method. A single surgeons practice (JPW) was retrospectively reviewed for all cuff tear arthropathy and osteoarthritis patients undergoing primary shoulder arthroplasty. (Zimmer, Warsaw, IN). Glenoid version was measured by 2 fellowship trained shoulder surgeons. Inter and intra-class correlation was measured. Results. The axial CT scans of 84 patients (cuff tear arthropathy and osteoarthritis) were evaluated. Inter and intra-class correlation was excellent (0.96, 0.97). Glenoid version was between 4.1 +/− 3.6 and 16.5 +/− 8.6 degrees for cuff tear arthropathy and osteoarthritis, respectively (p < 0.0001). Conclusion. Our observation of near neutral glenoid version in patients with cuff tear arthropathy has not been reported in the literature. The anatomical version of the glenoid may be a risk factor in patients undergoing rotator cuff repair. This may predispose certain individuals to cuff tear arthropathy compared to those with increased retroversion

Total shoulder arthroplasty has gone through several generations, as instruments and implant designs have given surgeons both more options in the alignment of the components and more guidance in the best choices to make. However, while the measurement of alignment has become more sophisticated, the importance of particular aspects of alignment to actual patient comfort and function has been less completely characterised. Overstuffing of the joint and proud humeral heads have been most associated with clinical failure. The efforts to avoid this can be divided into two camps: 1.) The anatomic school, who believe an experienced surgeon can divine the correct anatomy that existed before the distortions of arthritis began, and that the surgeon should make free-hand cuts and alignments to restore the normal anatomy. 2.) The cutting-guide school, who believe that average versions and positions avoid error and that soft-tissue balancing requires occasional deviations from “normal” anatomy. Reverse total shoulder replacement in contrast is a semi-constrained implant, with built-in “internal impingement” at the extremes of motion, which can cause notching and/or instability (levering out). Initial European experience favored placing the humeral component in 0 degrees, but most surgeons have gravitated toward 15–20 degrees of retroversion to allow easy conversion from/to a hemiarthroplasty as needed. Increased retroversion may block internal rotation, and increased anteversion limits external rotation

Assessing glenoid version is important for a successful total shoulder arthroplasty. Glenoid version is defined as the orientation of the glenoid cavity in relation to a plane perpendicular to the scapula body. Glenoid revision averages between 1 to 2 degrees of retroversion and varies between race and sex. In general glenoid retroversion is overestimated by 6.5 degrees on plain radiographs. Furthermore standard axial 2D CT is aligned to the patient's body and not aligned to the scapula. Therefore 3D reconstructions generated from standard CT allows for analysis of the scapula as a free body and correct version measurements can be made unaffected by positioning. If you add a computer modeling coordinate system in which implants can be added, then computer simulation surgery can be performed. This is important because implanting a glenoid component in excessive retroversion leads to increased stress at the glenoid component and cement mantle and decreased contact with the humeral component. Also excessive reaming of the glenoid surface to neutral retroversion can lead to excessive bone loss and penetration of the glenoid vault by either the pegs or the keel of the glenoid component

INTRODUCTION. The glenoid version assessment is crucial step for any Total Shoulder Arthroplasty (TSA) procedure. New methods to compute 3D version angle of the glenoid have been proposed. These methods proposed different definitions of the glenoid plane and only used 3 points to define each plane on the 3D model of the scapula. In practice, patients often come to consultation with their CT-scans. In order to reduce the x-ray dose, the scapulae are often truncated on the inferior part. In these cases, the traditional scapula plane cannot be calculated. We hypothesised that a new plane definition, of the scapula and the glenoid, that takes into account all the 3D points, would have the least variation and provide more reliable measures whatever the scapula is truncated or not. The purpose of the study is to introduce new fully automatic method to compute 3D glenoid version for TSA preoperating planning and test its results on artificially truncated scapulae. MATERIAL AND METHODS. Volumetric preoperative CT datasets have been used to derive a surface model shape of the shoulder. The glenoid surface is detected and a 3D version and inclination angle of the glenoid surface are computed. We propose a new reference plane of the scapula without picking points on the 3D model. The method is based on the mathematical skeleton of the scapula and the least squares plane fitting. Specific software has been developed to apply the plane fitting in addition the automatic segmentation process. An orthopedic surgeon defined the traditional scapular plane based on 3 points and applied the measures on 12 patients. The manual process has been repeated 3 times and the intra-class correlation coefficient (ICC) was calculated to compare the results with our automatic method. To validate the reliability of the new plane relating to truncated scapulae, we have measured the 3D orientation variation on 37 scapulae. Nine iterations have been applied on each scapula by cutting 5mm of the scapular inferior part. RESULTS. The ICC of the scapula plane orientation for the three orientation components (x, y, z) were 0.98, 0.99 and 0.89 respectively. The reliability results applied by cutting the inferior side show good results with means: 0.01±0.01 mm, 0.01±0.01 mm and 0.02±0.02 mm for X, Y, Z respectively. CONCLUSION. New referential scapular plane has been proposed to compute 3D glenoid version. The method is fully automatic and doesn't need manual positioning of points on the 3D points. The orientation of the new plane is correlated with the standard scapular plane. The study showed that plane orientation is reasonably constant while truncating the scapula body till 45mm of cut on the inferior and the medial side. This is the only study that proposes a reference plane for truncated scapula

Introduction. Reverse total shoulder arthroplasty continues to have a high complication rate, specifically with component instability and scapular notching. Therefore, the purpose of this study was to quantify the effects of humeral component neck angle and version on impingement free range of motion. Methods. A total of 13 cadaveric shoulders (4 males and 9 females, average age = 69 years, range 46 to 96 years) were randomly assigned to two studies. Study 1 investigated the effects of humeral component neck angle (n=6) and Study 2 investigated the effects of humeral component version (n=7). For all shoulders, Tornier Aequalis® Reversed Shoulder implants (Edina, MN) were used. For study 1, the implants were modified to 135, 145 and 155 degree humeral neck shaft angles and for Study 2 a custom implant that allowed control of humeral head version were used. For biomechanical testing, a custom shoulder testing system that permits independent loading of all shoulder muscles with six degree of freedom positioning was used. (Figure 1) Internal control experimental design was used where all conditions were tested on the same specimen. Study 1. The adduction angle and internal/external humeral rotation angle at which impingement occurred were measured. Glenohumeral abduction moment was measured at 0 and 30 degrees of abduction, and anterior dislocation forces were measured at 30 degrees of internal rotation, 0 and 30 degrees of external rotation with and without subscapularis loading. Study 2. The degree of internal and external rotation when impingement occurred was measured at 0, 30 and 60 degrees of glenohumeral abduction in the scapular plane with the humeral component placed in 20 degrees of anteversion, neutral version, 20 degrees of retroversion, and 40 degrees of retroversion. Statistical analysis was performed with a repeated measures analysis of variance with a Tukey post-hoc test with a significance level of 0.05. Results. Study 1. Adduction deficit angles for 155, 145, and 135 degree neck-shaft angle were 2 ± 5 degrees of abduction, 7 ± 4 degrees of adduction, and 12 ± 2 degrees of adduction (P <0.05), respectively. Impingement-free angles of humeral rotation and abduction moments were not statistically different between the neck-shaft angles. The anterior dislocation force was significantly higher for the 135degree neck-shaft angle at 30 degrees of external rotation and significantly higher for the 155 degree neck shaft angle at 30 degrees of internal rotation (P<.01). The anterior dislocation forces were significantly higher when the subscapularis was loaded (P <0.01). Study 2. Maximum external rotation was the limiting position for impingement particularly at 0 degrees of abduction. Maximum external rotation before impingement occurred increased significantly with increasing humeral retroversion (p < 0.05) (Figure 2). No impingement or subluxation occurred at any humeral version in 60 degrees of glenohumeral abduction. Conclusion. In reverse shoulder arthroplasty, 155 degree neck-shaft angle was more prone to impingement with adduction but had the advantage of being more stable. In addition, 40 degrees of retroversion has the largest range of humeral rotation without impingement

Total shoulder arthroplasty has gone through several generations, as instruments and implant designs have given surgeons both more options in the alignment of the components and more guidance in the best choices to make. However, while the measurement of alignment has become more sophisticated, the importance of particular aspects of alignment to actual patient comfort and function has been less completely characterised. Overstuffing of the joint and proud humeral heads have been most associated with clinical failure. The efforts to avoid this can be divided into two camps:. The anatomic school, who believe an experienced surgeon can divine the correct anatomy that existed before the distortions of arthritis began, and that the surgeon should make free-hand cuts and alignments to restore the normal anatomy. The cutting-guide school, who believe that average versions and positions avoid error and that soft-tissue balancing requires occasional deviations from “normal” anatomy

Glenohumeral arthritis is associated with eccentric posterior glenoid wear and subsequent retroversion. Total shoulder arthroplasty provides a reliable and robust solution for this pattern of arthritis but success may be tempered by malposition of the glenoid component, resulting in pain, functional impairment, prosthetic loosening and ultimately failure. Correction of glenoid retroversion through anterior eccentric reaming, prior to glenoid component implantation, is performed to restore normal joint biomechanics and maximise implant longevity. The aim of this study was to assess whether magnetic resonance imaging (MRI) or plain axillary radiography (XR) most accurately assessed glenoid version and hence provided the optimal modality for pre-operative templating. Glenoid version was assessed in pre-operative shoulder MRIs and axillary radiographs (XR) by two independent observers in forty-eight consecutive patients undergoing total shoulder arthroplasty. The mean glenoid version measured on magnetic resonance imaging was −14.3 degrees and −21.6 degrees on axillary radiographs (mean difference −7.36, p=<0.001). Glenoid retroversion was overestimated in 73% of XRs. Intra-observer and inter-observer reliability coefficients for MRI were 0.96 and 0.9 respectively. Intra-observer and inter-observer reliability coefficients for XR were 0.8 and 0.71 respectively. Axillary radiographs significantly overestimate glenoid retroversion and are less precise than shoulder magnetic resonance, which provides excellent intra- and inter-observer reliability. MRI is a useful pre-operative osseous imaging modality for total shoulder arthroplasty as it offers a more precise method of determining glenoid version, in addition to the standard assessment rotator cuff integrity

Background:. Recently a new version of the Knee Society Knee Scoring System has been developed, adapted to the lifestyle and activities of contemporary patients with a Total Knee Arthroplasty (TKA). It is subdivided into 4 domains including an Objective Knee Score, a Satisfaction Score, an Expectations Score and a Functional Activity Score. Before this scale can be used in non-English speaking populations, it has to be translated and validated for specific populations. The aim of this study was to translate and validate the New Knee Society Knee Scoring System (new KSS) for Dutch speaking populations. Materials and Methods:. A Dutch translation of the New KSS was established using a forward-backward translation protocol. 137 patients undergoing TKA were asked to complete the Dutch translation of the New KSS as well as the Dutch WOMAC, Dutch KOOS and the Dutch SF12. To determine the test-retest reliability, 53 patients were asked to fill out a second questionnaire with one-week interval. We tested the test-retest reliability of the subjective domains of the New KSS by assessing the intra-class coefficient and the Pearson correlation coefficient between the first and second questionnaires. Systematic differences between the first and second questionnaires were investigated with T-tests and non-parametric statistics. Internal consistency of the Dutch new KSS was evaluated with Cronbach's alpha. The construct validity of the Dutch New KSS was determined by comparing it to the Dutch WOMAC, Dutch KOOS and Dutch SF12 using Pearson correlation coefficients. Content validity was assessed by examining the distribution and the floor and ceiling effects of the Dutch version of the new KSS. Results:. The reliability of the Dutch translation of the New KSS proved excellent with an ICC ranging from 0.75 to 0.92 for single measures and from 0.85 to 0.96 for average measures in the different domains. Cronbach's alpha ranged from 0.86 to 0.96 indicating good to excellent internal consistency. Paired t-tests and non-parametric statistics revealed no significant differences between the first and second questionnaires while paired samples correlations were highly significant (p < 0.001). The Dutch New KSS correlated well with the Dutch WOMAC score (r = 0.81; p < 0.001), the Dutch KOOS (r = 0.77; p < 0.001), and the Dutch SF12 (r = 0.62; p < 0.001). Content validity was good with a normal distribution of the calculated scores and absence of floor or ceiling effects. Conclusions:. The validation procedure demonstrated that the proposed Dutch version of the New Knee Society Knee Scoring System is a reliable and valid instrument for evaluating symptoms, function, expectations and satisfaction after TKA in Dutch speaking patients

Total shoulder arthroplasty has gone through several generations as instruments and implant designs have given surgeons both more options in the alignment of the components and more guidance in the best choices to make. However, while the measurement of alignment has become more sophisticated, the importance of particular aspects of alignment to actual patient comfort and function has been less completely characterised. Overstuffing of the joint and proud humeral heads have been most associated with clinical failure. The efforts to avoid this can be divided into two camps:. The anatomic school, who believe an experienced surgeon can divine the correct anatomy that existed before the distortions of arthritis began, and that the surgeon should make free-hand cuts and alignments to restore the normal anatomy. The cutting-guide school, who believe that average versions and positions avoid error and that soft-tissue balancing requires occasional deviations from “normal” anatomy

Introduction. Version abnormalities of the femur, either retroversion or excessive anteversion, cause pain and hip joint damage due to impingement or instability respectively. A retrospective clinical review was conducted on patients undergoing a subtrochanteric derotation osteotomy for either excessive anteversion or retroversion of the femur. Methods. A total of 49 derotation osteotomies were performed in 39 patients. There were 32 females and 7 males. Average age was 29 years (range 14 to 59 years). Osteotomies were performed closed with an intramedullary saw (Figure 1). Fixation was performed with a variety of intramedullary nails. Patients requiring a varus or valgus intertrochanteric osteotomy were excluded. Pure rotational corrections only were performed. Twenty-four percent of patients had a retroversion deformity (average −8° retroversion, range +1 to −23°), 76% had excessive anteversion of the femur (average +36° anteversion, range +22° to +53°). Etiology was post-traumatic in 5 (10%), diplegic cerebral palsy in 4 (8%), fibrous dysplasia in 2 (4%), Prader-Willi Syndrome in 1 (2%) and idiopathic in 37 (76%). Previous surgery had been performed in 51% of hips. Fifty-seven percent underwent concomitant surgery with the index femoral derotation osteotomy, including hip arthroscopy in 39% (labral debridement alone or with femoral neck osteochondroplasty), a tibial derotation osteotomy in 12% and periacetabular osteotomy in 6%. Concomitant tibial osteotomies were performed to correct a compensatory excessive external tibial torsion that would be exacerbated in the correction of excessive femoral anteversion. The modified Harris Hip Score was used to assess the results in patients with a minimum of 24 months follow-up. Results. There were no non-unions. Average time to union was 3.3 months. One late infection occurred 10 months after surgery, treated successfully with hardware removal and antibiotics. Two patients, one with Prader-Willi syndrome and one with Ehlers-Danlos syndrome, were converted to total hip replacement. At an average follow-up of 6.1 years (range 2 to 19.1 years), the modified Harris Hip Score improved by 26 points (p< 0.001, Wilcoxon signed-ranks test). The results were rated as excellent in 71%, good in 22%, fair in 5% and poor in 3%. Subsequent surgery was required in 73%, 93% of which were hardware removals. Discussion and Conclusion. A closed, subtrochanteric derotation osteotomy of the femur is a safe and effective procedure to treat either femoral retroversion or excessive anteversion. Excellent or good results were obtained in 93%, despite the need for subsequent hardware removal in more than two-thirds of the patients. For figures/tables, please contact authors directly.

Introduction:. Dislocation is still one of the major complications in total hip arthroplasty. Among other factors, it is important to maximize the intended range of movement (iROM) in order to reduce the risk for prosthetic impingement and to prevent edge loading in order to avoid surface damage and squeaking. Therefore, both components should be positioned in accordance to the new combined safe-zone for correct combined version and inclination aiming for an optimal relative orientation of both components. This study shows how this optimal combined orientation of both components can be determined for a specific total hip prosthetic system and how the result can be transferred to surgery and accomplished intraoperatively using minimal-invasive stem-first technique. Material and Methods:. 829 minimal-invasive total hip arthroplasties have been performed from 2007 to 2013 in our institution. In all of these surgeries a minimal-invasive direct anterior approach (DAA) was applied. All patients were positioned supine on a proprietary orthopedic table. In 168 cases a system-specific mechanical aiming device was used intraoperatively in order to control the combined version and inclination according to the specific safe-zone by orienting the prosthetic socket in relation to the prosthetic stem. This is called “stem-first technique” meaning that the prosthetic stem dictates the orientation of the socket. It does not mean the sequence of implantation. It's specific advantage is that the stem redirects the socket if it's position is modified. It equally applies to standard, anatomic (Fig. 1) or short stems (Fig. 2). The socket orientation is not primarily referred to bony landmarks of the pelvis but to the neck of the stem. Nevertheless the surgeon has to look for sufficient fixation of the socket within the acetabular bone. Leg length was measured in the surgical field additionally and prosthetic offset was adjusted according to the preoperative planning. All other patients were operated on in our standard minimal-invasive DAA-procedure. The majority of the patients suffered from osteoarthritis, their mean age was 68 years. Results:. Optimal component orientation for each prosthesis system was derived from its 3D-model by simulating hip joint motion in the physiologic range of motion. Optimal component orientation means maximizing the area of the combined safe-zone. In the stem-first group cup orientation was in the new combined safe-zone in 94% of the cases and no squeaking or prosthetic impingement did occur in any of these patients. Leg length did not differ more than +/− 5 mm. 83% of all patients receiveda ceramic-on-ceramic articulation, one early dislocation did occur and treated by closed reduction. Conclusion:. Stem-first technique is ideally suited for the minimal-invasive direct anterior approach in total hip arthroplasty to control the combined orientation of the prosthetic components and to achieve excellent clinical results. It assists the surgeon in aligning the cup and the stem according to their correct combined orientation in order to get an optimal range of movement especially in young patients

Introduction. Spatial orientation of the pelvis in the sagittal plane is a key parameter for hip function. Pelvic extension (or retroversion) and pelvic flexion(or anteversion) are currently assessed using Sacral Slope (SS) evaluation (respectively SS decrease and SS increase). Pelvic retroversion may be a risk situation for THA patients. But the magnitude of SS is dependant on the magnitude of pelvic incidence (PI) and may fail to discriminate pelvic position due to patient's anatomy and the potential adaptation mechanisms: a high PI patient has a higher SS but this situation can hide an associated pelvic extension due to compensatory mechanisms of the pelvic area. A low PI patient has a lower SS with less adaptation possibilities in case of THA especially in aging patients. The individual relative pelvic version (RPV) is defined as the difference between « measured SS » (SSm) minus the « normal SS »(SSn) described for the standard population. The aim of the study was to evaluate RPV in standing and sitting position with a special interest for high and low PI patients. Materials and Methods. 96 patients without THA (reference group) and 96 THA patients were included. Pelvic parameters (SS and PI) were measured on standing and sitting EOS images. RPV standing (SSm-SSn) was calculated using the formula SSm – (9 + 0.59 × PI) according to previous publications. SSn in sitting position was calculated according to PI using linear regression: RPV sitting was calculated using the formula RPV = SS – (3,54+ 0,38 × PI). Three subgroups were defined according to pelvic incidence (PI): low PI <45°, 45°<normal PI<65° or high PI>65°. Results. For THA patients, pelvic parameters were:. SSm standing 41° (SD 11°; 8°.73°). SSm sitting 25° (SD 12°;−3°.54°). SSm variation 16°(SD 11°; 9°.46°). RPV standing −2°(SD 9°; −27°.21°). RPV sitting 7° (SD 10; −15°.29°). For non THA patients, pelvic parameters were:. SSm standing39° (SD 10°; 13°.63°). SSm sitting 17° (SD 11°;−5°.48°). SSm variation 27°(SD 13°; −27°.46°). RPV standing −1°(SD 7°; −29°.12°). RPV sitting 0° (SD 10,5; −29.35). Standing-sitting SS variations and RPV were not correlated with PI. Low PI incidence patients had very low RPV standing and sitting. In non THA patients RPV standing and sitting were very low. In THA patients standing-sitting SS variations and RPV were higher than for non THA patients. Sitting RPV was higher than in standing position. Discussion, Conclusion. The overall analysis of SS has limitations: higher or lower SS may be linked to 2 factors: pelvic morphology (PI) and sagittal orientation of the pelvis. RPV and PI were not correlated: a higher or lower value of RPV directly represents the sagittal orientation of the pelvis. Low PI patients have a specific postural pattern with low pelvic adaptability. THA patients specificity for RPV needs further studies for understanding the impact on postoperative rebalancing and instability problems

[Introduction]. One of the modern design total knee arthroplasty (TKA) system, the NexGen Legacy posterior-stabilized (LPS) Flex prosthesis, has been in use at our hospital since 2001. Between 2006 and 2011, NexGen LPS-Flex primary TKA were mainly performed in combination with a cemented short-keeled minimally invasive version tibial tray (MIS tibial component) instead of the traditional NexGen stemmed tibial tray. We observed some cases required early revision of isolated tibial component in primary TKA performed in this period. Therefore, our objectives were to report the series of this revision cases and to consider this failure mechanism. [Patients & Methods]. A total of 526 primary TKAs were performed using a NexGen LPS-Flex prosthesis and MIS tibial component during five-year period at our hospital. The mean age was 74 years at the time of the index procedure. We assessed revision rate of this tibial tray in this study and described clinical course of the revision cases. We also examined the clinical and radiographic features which could be associated with the failure. [Results]. The mean duration of follow-up was 2.5 years and there were 13 knees received tibial component revision during this period. Twelve knees were diagnosed with osteoarthritis and one knee with rheumatoid arthritis. The duration between primary TKA and revision averaged at 3.3 years, and the mean age at the second procedure was 67 years. TKAs were performed without applying the tibial central extension stem in all 13 knees, and thick polyethylene insert like 17 or 20 mm were selected for seven and 14 mm for five of 13 knees, that were the typical features on the primary TKA. Postoperative course of all 13 cases was uneventful and 10 of 13 knees achieved deep knee flexion over at 125 degrees. Prerevision radiographs showed characteristic pattern with tibial tray debonding at the cement-implant interface and subsidence into varus and flexion in all 13 knees. In all cases, intraoperative findings revealed a grossly loose tibial component with most of the cement mantle still attached to the bone. No case exhibited signs of macroscopic polyethylene wear and femoral component loosening. [Discussion]. The most common reason for failure of TKA is infection followed by implant loosening, polyethylene wear, and instability. Several studies document survival rates of over 90% up to 20 years with modern TKA designs using a cemented stemmed tibial component. Although failure of the tibial component was more prevalent in some early TKA designs, in recent years, failure of tibial fixation has been a rare cause of revision. Our experience with early aseptic loosening of this tibial component has suggested the low-profile design with no central stem as a cause for accelerated failure. Furthermore, other factors associated with increased this failure could include a thicker insert and postoperative achievement of high flexion

Introduction

Appropriate femoral stem anteversion is an important factor in maintaining stability and maximizing the performance of the bearing after total hip replacement (THR). The anteversion of the native femoral neck has been shown to have a significant effect on the final anteversion of the stem, particularly with a uncemented femoral component. The aim of this study was to quantify the variation in native femoral neck anteversion in a population of patients requiring total hip replacement.

Combined anteversion angle of acetabular component and femeral neck is an important factor for total hip arthroplasty (THA) as it may affect impingement and dislocation. Previous studies have collected data mainly from direct measurements of bone morphology or manual measurements from 2D or 3D radiolographic images. The purpose of this study was to electronically measure the version angles in native acetabulum and femur in matured normal Caucasion population using a novel virtual bone database and analysis environment named SOMA™. 221 CT scans from a skeletally mature, normal Caucasian population with an age range of 30–95 years old. The population included 135 males and 86 females. CT data was converted to virtual bones with cortical and cancellous boundaries using custom CT analytical sofware. (SOMA™ V.3.2) Auxillary reference frames were constructed and measurements were performed within the SOMA™ design environment. Acetabular Anteversion (AA) angle as defined by Murray. 1. was measured. The acetabular rim plane was constructed by selecting 3 bony land marks from pubis, ilium and ischium. A vector through acetabular center point and normal to the rim plane defined the plane for the AA measurement. The AA was defined as the angle of this plane relative to the frontal (Coronal) plane of the pelvis. The Femoral Neck Anteversion (FNA) angle was measured from the neck axis plane to the frontal (Coronal) plane as defined by the posterior condyles. The neck axis plane was constructed to pass through femoral neck axis perpendicular to the transverse plane. The combined anteversion angle was computed as the summation of acetabular and femoral anteversion angles. Student's t tests were performed to compare gender difference with an assumed 95% confidence level. The mean AA angle for total population was 25.8°, SD=7.95°. The mean AA for male was 24.8°, SD=5.93° and for female was 27.3°, SD=7.14°. P=0.009. The mean FNA angle for total population was 14.3°, SD=6.52°. The mean FNA for male was 13.5°, SD=7.97° and for female was 15.5°, SD=7.80°. P=0.058. The mean combined anteversion angle for total population was 40.1°, SD=10.76°. The mean combined anteversion angle for male was 38.3° SD=10.39 ° and for female was 42.8° SD=10.83 °. P=.0002. The plot of AA as a function of FNA shows weak correlation for both male and female. (Figure 1) The frequency distribution is shown in Figure 2. The results showed the both AA, FNA and combined anteversion angles were significantly smaller in male population than that in female population. The FNA angle of the cementless femoral stem can be smaller than with the natural femur, therefore a higher AA or higher posterior build up may be required for the acetabular component for optimal function of a THA

The Disability of Arm Shoulder and Hand (DASH) score questionnaire is a common self-administered tool to assess symptom severity and function in patients with injuries or pathology of the upper limb. However, having such a pertinent tool only in English is limiting in multi-cultural and multilingual populations where English is not always the first language, such as our South African context. IsiZulu is the most widely spoken language in South Africa (approximately 25% of the population). There are certain instances in research, particularly in international studies, where non-English speaking individuals need to be excluded based on translator reliability. This puts our institutions at a disadvantage by not being able to contribute to research. As per the international Institute of Work and Health (IWH), we followed the 5 stage guidelines to achieve the most appropriate linguistic and cultural adapted translation for our setting. (1) Two independent translations from English to isiZulu. (2) A synthesis of the 2 initial translations. (3) Two independent back-translations from the synthesized isiZulu version into English. (4) Expert panel (consisting of university lecturers and official translators) to review all versions and re-create an optimized synthesized version. (5) Pre-testing of the final optimized synthesized version in a pilot study. This rigorous process allowed for a concise and more culturally relevant translation for use in our population. The fourth stage in the process was integral in synthesizing the tool while considering the colloquial and semantic differences and resolving them with appropriate equivalents. The IWH guidelines aids in the cross-cultural adaptation of the DASH score while remaining valid and comparable to the original English version. This is beneficial in multi-national research projects and allows for the standardization of health outcome measures

Aim. Synovial calprotectin point-of-care test (POC) has shown promising clinical value in diagnosing periprosthetic joint infections (PJIs). However, limited data are available in unclear cases. Moreover, cut-off values for calprotectin lateral flow assay (LFA) and enzyme-linked immunosorbent assay (ELISA) need to be adapted. The aim of this study was to evaluate the performance of an upgraded and more sensitive version of a synovial calprotectin LFA along with ELISA immunoassay in patients with septic, aseptic, and unclear cases. Methods. Overall, 206 prospectively collected periprosthetic synovial fluid samples from 169 patients (106f/63m; 38 hip/131 knee) who underwent revision surgeries were retrospectively evaluated for calprotectin concentration. The following groups were analyzed: unexpected negative cultures (UNC; 32/206), unexpected positive cultures (UPC; 28/206), and unclear cases (65/206) with conflicting clinical results. In addition, we added a true aseptic (40/206), and true septic (41/206) control groups according to the international consensus meeting (ICM) 2018 PJI classification. Calprotectin concentration was determined by a rapid quantitative LFA (n=206) (Lyfstone®, Norway), and compared to calprotectin ELISA immunoassay (171/206). For the determination of a new calprotectin cut-off value, analysis of the area under the curve (AUC) followed by Youden's J statistic were performed using the calproctectin values from clear septic and aseptic cases. Sensitivity and specificity for calprotectin were calculated. All statistical analyses were performed using IBM-SPSS® version 25 (Armonk, NY, USA). Results. An absolute calprotectin value of 43 mg/ml, and 40.15 mg/ml was determined to be the optimal cut-off for PJI diagnosis using the new version of the LFA and ELISA, respectively. With this cut-off, the sensitivity and specificity of synovial calprotectin concentration for PJI were 88.1% (95% CI 77.8 to 94.7) and 76.6% (95% CI 61.9 to 87.7) for LFA, and 97.06% (95% CI 89.8 to 99.64) and 93.6% (95% CI 82.5 to 98.66) for ELISA, respectively. Of the evaluated groups, UNC 30/32 (93.8%) vs 26/27 (96.3%), UPC 6/28 (21.4%) vs 4/21 (19%), and unclear samples 45/65 (69.2%) vs 30/56 (53.6%) displayed a high likelihood of infection by using LFA, and ELISA, respectively. Conclusion. The upgraded version of the calprotectin quantitative LFA with a new suggested cut-off for infected samples showed additional clinical value in identifying cases at high risk of infection in unclear PJI revisions. Additionally, calprotectin ELISA immunoassay had a better performance than LFA. Further large sample-size validation studies are warranted