Purpose. Due to the aging population, an increasing proportion of elderly patients with soft tissue sarcoma are presenting to cancer centers. This population appears to have a worse prognosis but the reasons for this has not been studied in depth. The purpose of this study is to examine the effect of age on the outcome of patients with extremity and trunk soft tissue sarcoma. Method. This is a multicenter study including 2071 patients with median age at operation of 57 years (1st quartile–3rd quartile: 42–70). The endpoints considered were local recurrence and metastasis with death as a competing event. Cox proportional hazards models were used to estimate hazard ratios across the age ranges with and without adjustment for known confounding factors. Results. Older patients presented with tumors that were larger and of higher grade. The proportion of positive margins increased progressively as patients aged, but radiation therapy was relatively underused in patients over 60 years old. Age was strongly associated with both local recurrence and metastasis. The 5-year cumulative incidences of local recurrence were 7.6% (4.2%–12.2%) for patients 30 years or younger and 13.8% (9.8%–18.5%) for patients 75 years and older; corresponding 5-year cumulative incidences of metastasis were 21.5% (15.7%–28%) and 32.5% (27%–38.2%) for the same groups. Age showed a non linear effect with a dramatic increase in the risk of local recurrence and metastasis after 60 years old. The increased risk of metastasis for older patients was explained by disparities in tumor characteristics at presentation, and additionally for local recurrence, by disparities in treatment. Conclusion. Age is associated with worse outcomes after resection of soft tissue sarcoma. Older patients have worse outcomes because they tend to present with tumors having more adverse prognostic features and they are also treated less aggressively. A significant effect of age that is not explained by known confounders remains

The Step Holter is a software and mobile application that can be used to easily study gait analysis. The application can be downloaded for free on the App Store and Google Play Store for iOS and Android devices. The software can detect with an easy calibration the three planes to detect the movement of the gait. Before proceeding with the calibration, the smartphone can be placed and fixed with a band or stowed into a long sock with its top edge at the height of the joint line, in the medial side of the tibia. The calibration consists in bending the knee about 20 to 30 degrees and then making a rotation movement, leaving the heel fixed to the ground as a rotation fulcrum. After calibration, the program records data related to lateral flexion, rotation, and bending of the leg. This data can be viewed directly from the smartphone screen or transmitted via a web link to the Step Holter web page . www.stepholter.com. by scanning a personal QR code. The web page allows the users to monitor the test during its execution or view data for tests done previously. By pressing the play button, it is possible to see a simulation of the patient's leg and its movement. With the analyze button, the program is capable of calculating the swing and stance phase of every single step, providing a plot with time and percentages. Finally, with the Get Excel button, test data can be conveniently exported for more in-depth research. The advantage of this application is not only to reduce the costs of a machine for the study of gait analysis but also being able to perform tests quickly, without expensive hardware or software and be used in specific spaces, without specialized personnel. Furthermore, the application can collect important data concerning rotation that cannot be highlighted with the classic gait analysis. The versatility of a smartphone allows tests to be carried out not only during walking but also by climbing or descending stairs or sitting down or getting up from a chair. This software offers the possibility to easily study any kind of patients; Older patients, reluctant to leave their homes for a gait analysis can be tested at home or during an office control visit. Step Holter could be one small step for patients, one giant leap for gait study simplicity. For any figures or tables, please contact authors directly

Background. Total Knee Arthroplasty (TKA) provides patients with significant improvements in quality of life. Subjective patient reported outcome measures (PROMs) are traditionally used to measure preoperative functional status and postoperative outcomes. However, there are limitations to PROMs. In particular, they provide virtually no functional information in the first 3 weeks after surgery, which could be used to guide the patient's recovery. Newly available wearable electronic sensors make it possible to: 1) measure important functional outcomes following TKA; 2) guide the patient's physical therapy (PT); and 3) provide real-time functional and clinical information to the provider. Compliance with PT after TKA is a challenge. Patients cite time, transportation, and cost as deterrents to PT appointments. However, an intensive PT program is essential in TKA. Surface sensor devices may be able to increase PT compliance by guiding patients through exercises at home. Additionally, these devices can transmit PT progress in real-time to the providers, allowing them to monitor and assist the patient's recovery. Our study investigates the feasibility of using a surface sensor device (TracPatch™) on patients following TKA. We sought to answer the following questions: 1) Will patients tolerate the device; 2) Will patients comply with device instructions; 3) Will patients be able to use the smart phone application; 4) Will the device collect, transmit, and store data as it was designed? We believe these fundamental questions must be answered as we enter the era of personal sensor-measured functional outcomes. Methods. 20 patients undergoing primary, unilateral TKA were enrolled in this IRB approved study. At the pre-surgical visit, patients were given instructions for the device and smart phone application. Each patient used the device in the week prior to surgery, and data was collected. The device was again applied in the operating room. For 3 weeks post-operatively, the device collected functional data, along with WOMAC, OKS, KSS, PROMIS, and VAS pain scores. A satisfaction survey was collected on the device. Results. The study results emphasize the importance of clear device instructions. Using the sensor and phone application prior to surgery was very helpful. The device was surprisingly well tolerated. Older patients were able to use the device without significant difficulty. Virtually all patients found the device helpful and, often fun. Physical therapists felt that the devices helped personalize the therapy program. The functional information from the device was much more helpful in guiding care in the first 3 weeks following surgery than PROM scores. Conclusion. It is anticipated that sensor devices of the kind tested in this study will have a major impact on the care of TKA patients. The purpose of this study was not to measure that impact. Our goal was to examine the factors that optimize the use of these devices. It is critical that clear device instructions be given to patients. Office procedures must be established to monitor use of the devices. If protocols are established for their use, surface sensors have the potential to provide invaluable information to TKA patients and caregivers

Peri-prosthetic distal femoral fractures around total knee replacement is a highly complex reconstructive challenge, particularly in the presence of bone comminution and poor bone quality in elderly patients. With the incidence of peri-prosthetic fractures ranging from 0.3% to 2.5%, this is becoming a common problem. Older patients with concomitant medical issues have a very limited tolerance for prolonged immobilisation. It is the author's practice to revise, rather that attempt to fix, peri-prosthetic fractures of the knee which are very close to the femoral or tibial implants, particularly when associated with osteoporosis and comminution. When compared to fracture fixation, distal femoral replacement has significantly shorter operative time, less blood loss, and shorter hospital stay. Patients have been shown to recover faster, have fewer complications, and left hospital sooner. The general assumption has been that the use of a distal femoral replacement prosthesis is cost prohibitive in revision total knee settings, however, initial differences in the price of the prosthesis are more than offset by a shortened hospital stay and a more rapid return to pre-fracture level of function

The aim of the study is to evaluate how patients over 65 years of age cope with the Ilizarov method of treatment, compared with patients a decade younger. Two age groups were selected, 50–65 years versus 65 years and over. 20 consecutive patients were recruited for each group. SF36 scores were completed pre-operatively, at 6 weeks post op and 6 weeks post frame removal. 41 patients were recruited in total. Seven patients were lost to follow up – 2 died, 2 became too ill to continue with treatment, 3 did not complete the SF36. This left 34 patients. T test was used to analyse the results. Both age groups showed an equal and statistically significant drop in SF36 scores whilst the Ilizarov frame was on (p<0.01 for each group). After frame removal, SF36 in the >65 group was not significantly different to pre-operative values. In the younger group, SF36 after frame removal was still significantly lower than pre-operative values (p<0.01). Age makes no difference in how patients cope with the ilizarov frame during treatment. Older patients have low pre-injury function levels, but appear to return to this level quickly after frame removal. Younger patients do not recover pre-injury function in 6 weeks after completion of treatment

Aim. To determine the preferable treatment for congenital pseudarthrosis of the tibia, we retrospectively reviewed 19 patients (20 limbs) treated consecutively over a 22 year period (1988–2007). Fifteen were followed up to maturity. The patients were assessed for union, leg length discrepancy (LLD), ankle valgus, range of ankle movement and distal tibial physeal injury. Results. The median age at surgery was 3 years. At surgery nineteen of the tibiae had a dysplastic constriction with a fracture (Crawford II-C or Boyd II) lesion. To obtain union in the 20 tibiae, 29 procedures were done. Nine failed primarily and required a second procedure to obtain union. Older patients (≥ 5 years) had a significantly higher success rate. Excision, intramedullary rodding and bone graft (IMR) was done in 14 tibiae: 10 (71.4%) were successful. Six of 10 primary operations and all 4 secondary operations after a previous failed procedure were successful. Ipsilateral vascularized fibula transfer (IVFT) was successful in 5 tibiae (3 primary and 2 secondary). Ilizarov with bone transport only, failed in two patients. Ilizarov with excision, intramedullary rodding and bone graft with lengthening was successful in 2 of 5 cases (40%); two sustained fractures at the proximal lengthening site. A median leg length discrepancy (LLD) of 3 cms occurred post surgery which was treated with contralateral epiphysiodesis. At maturity 3 patients had a LLD of ≥ 2cms. Six limbs had ankle valgus and were treated with stapling and tibio-fibular syndesmosis. Decreased range of movement of the ankle (< 50%) occurred in 7 patients. Distal tibial physeal injury occurred in 4 patients and was associated with repeated rodding. Conclusion. We concluded that surgery should be delayed as long as possible. If there is adequate tibial purchase for the rod distally, IMR is the best option. If purchase is inadequate, Ilizarov with rodding will avoid ankle stiffness. Epiphysiodesis is preferable to lengthening because of the risk of fracture above the rod. IVFT is a good option as a secondary procedure. NO DISCLOSURES

The clinical guidelines for hip fracture management indicate that indwelling foley catheterization should be avoided when possible. Alternatives to indwelling catheters such as intermittent or condom catheters are recommended. Appropriate catheterization usage is important in hip fracture patients to avoid complications such as urinary tract infections (UTIs) (7–24% of patients) or post-operative urinary retention (POUR) (20–56% of patients). In this study, we aim to, (1) evaluate catheter usage in hip fracture patients at a large tertiary care centre, (2) compare current practices in catheter usage to clinical guidelines, (3) determine the incidence of POUR in hip fracture patients (4) determine the factors that increase one's risk of developing POUR. We analyzed 584 hip fracture patients between the ages of 18 and 102 admitted between November 2015 and October 2017 at a tertiary Care Hospital. Data collected included patient demographics, fracture pattern, surgical procedure, length of stay, co-morbidities and catheter use. We compared actual catheter usage to suggested guidelines to determine whether recommendations were being followed. We also investigated the incidence of POUR and risk factors associated with developing POUR. Independent samples t-test were used to compare continuous dependent variables in bivariate analyses and a logistic regression was used to determine predictors of developing POUR, catheter usage, and length of stay in multivariate analyses. T. Over three quarters (76.9%) of patients with hip fractures were treated with a catheter during their admission, 63.5% of which were inserted pre-operatively and 36.5% of which were inserted post-operatively. Indwelling catheters accounted for 92.2% of catheters used, while intermittent and catheter condoms accounted for 7.8%. POUR occurred in 98 of 584 cases (16.7%). Age (p = 0.004), gender (p=0.001), and presence of kidney disease (p=0.033) were statistically significant predictors of POUR. Fracture pattern (p=0.825), surgical procedure (p=0.298), diabetes mellitus (p=0.309) and UTI in the past 60 days (p=0.848) or on admission (p=0.999) were not statistically significant predictors of developing POUR. The development of POUR did not significantly increase length of stay (p=0.558). There was no statistically significant correlation between developing POUR and extended post-operative catheter use over 24 hours (p=0.844) or 48 hours (p=0.862). Patients who received a catheter pre-operatively or post-operatively for longer than 24 hours were not significantly more likely to develop POUR (p=0.057). Catheter use was common for all hip fracture patients and indwelling catheters were used in the overwhelming majority of cases. The high frequency of catheter usage, and specifically indwelling catheter usage, suggests that there is low compliance with the clinical guidelines for hip fracture patients. The incidence of POUR was 17%. Older, male patients were more likely to develop POUR. Although not statistically significant, more appropriate catheter use may decrease urinary complications such as POUR

Purpose. Our hypothesis was that closed tibia fractures treated with intramedullary nails are impacted by surgeon and center volumes. Method. Data from 813 patients with closed tibia fractures were obtained from the SPRINT study. Using multiple regression, we examined the effect of center and surgeon volume (categorized as high, moderate, or low), and geographic differences by country (Canada, USA, and the Netherlands) on health-related quality-of-life and revision surgeries to gain union at one year. Our measures of quality-of-life were the Short-Form 36 Health Survey Questionnaire (SF-36 PCS) and the Short Musculoskeletal Function Assessment (SMFA). Results. Patients treated by moderate volume surgeons had a reduced risk of reoperation versus patients treated by low volume surgeons (odds ratio =0.54, 95% CI = 0.33 to 0.89, p=0.02). No effects of surgeon volume were seen for the other outcomes. Patients treated at moderate volume centers had poorer quality of life at one year than patients treated at low volume centers, based on the SMFA Bother score (difference = 7.33, 95% CI = 2.65 to 12.01). This effect was not seen with the other outcomes. Patients with isolated fractures have better quality-of-life at one year, based on all three measures, p<0.001. Older patients have poorer SMFA scores at one year than younger patients, p<0.001. There were no significant differences by country. Conclusion. The traditional volume versus outcome relationship for closed tibial fractures within intramedullary nailing does not hold. Further analyses in other areas of orthopaedic trauma surgery are advisable

Background. Autologous chondrocyte implantation (ACI) and mosaicplasty (MP) are two methods of repair of symptomatic articular cartilage defects in the adult knee. This study represents the only long-term comparative clinical trial of the two methods. Methods. A prospective, randomised comparison of the two modalities involving 100 patients with symptomatic articular cartilage lesions was undertaken. Patients were followed for ten years. Pain and function were assessed using the modified Cincinnati score, Bentley Stanmore Functional rating system and visual analogue scores. ‘Failure’ was determined by pain, a poor outcome score and arthroscopic evidence of graft disintegration. Results. Patients had a mean age at index operation of 31. There was a long mean pre-op duration of symptoms of seven years and the defects had an average of 1.5 operations (excluding arthroscopy) to the articular cartilage lesion prior to the cartilage repair surgery. The aetiology of the articular cartilage defects was mainly trauma; some patients had osteochondritis dissecans or chondromalacia patellae. Five patients were lost to follow-up. A total of 23 out of 42 mosaicplasty patients failed, 10 out of 58 ACI patients failed (p<0.001). Most patients did well for the first two years when there was a steep failure of mosaicplasty patients, after which the failure rate was more constant. There was a low steady failure rate of ACI over the 10 years. Older patients treated by ACI did worse than younger patients; age was less of a prognostic indicator in MP. Patients irrespective of gender or aetiology of the defect fared better with ACI than MP. Conclusion. At ten years, patients who underwent cartilage repair using ACI fared significantly better than those who underwent mosaicplasty

The universal availability of CT scanners has led to lower thresholds for imaging despite significant financial costs and radiation exposure. We hypothesized that this recent trend increased the use of CT for upper limb articular fractures and led to more frequent operative management. A 5-year retrospective study (01/07/2005–30/06/2010) was performed on all adult patients with upper extremity articular fractures (AO: 1.1, 1.3, 2.1 and 2.3) admitted to a Level-1 Trauma Centre. Patients were identified from the institutions prospectively maintained AO classification database. A total of 1651 patients with 1735 upper extremity articular fractures were identified. 1131 (65%) fractures were operated on. 556 (32%) fractures had CT imaging, 429 (77%) of these had operative management. 289 (17%) patients had multiple injuries and 168 (10%) received a scan of at least 1 other body region. There was a gradual increase in CT use and operative management 1.1, 1.3 and 2.1 fractures. Operation rates for 2.3 fractures unchanged but CT imaging frequency declined. In patients younger than 55 years operative management remained stable at 71% throughout the 5-year period considering all four regions. Overall CT use was stable at 38%, however scan rates for distal radius decreased but for proximal forearm increased. The operative management of patients older than 55 years has increased significantly from 56% in 2005, to 70% in 2010. The most marked increase was observed in proximal humerus fractures. Except for 2.3 fractures, CT rates showed similar but less pronounced increases. There is no increase in CT usage and operative management in younger upper limb articular fracture patients. CT utilization is even decreasing in distal radius fractures. Older patients are less likely to get CT scanned but there is a significant increase in operative management of their upper limb articular fractures

Introduction. The new Knee Society Score has been developed and validated, in part, to characterize better the expectations, components of satisfaction, and the physical activities of the younger, more diverse modern population of TKA patients. This study aims to reveal patients' activity levels' post-TKA and to determine how it contributes to their subjective evaluation of the surgery. Methods. As part of a multi-centered and regionally diverse study sponsored by the Knee Society, the new Knee Society Score (KSS) was administered 243 patients (44% male; avg 66.4years; 56% female, avg 67.7years) following primary TKA (follow up > 1year, avg. 25mos). The new, validated KSS questionnaire consists of a traditional objective component, as well as subjective components inquiring into patient symptoms, satisfaction, expectations and activity levels as well as a survey of three physical activities that are viewed as important to the patients. Responses were analyzed as a whole group and as subgroups of male and female and as younger (<65) and older (>65). Results. Post-TKA, knee function met or exceeded 84% of patients' expectations, with 49% of patients reporting that their knee always feels normal. While performing standard activities (eg turning, climbing stairs), the majority of patients (78%) experienced few symptoms referable to the knee. Fewer (47%) report that they remain asymptomatic while performing more demanding (‘advanced’) activities (eg squatting, running). Distance walking (52%), swimming (28%) and stationary biking (25%) were among activities that were most commonly selected as personally important. Activities such as golf (Male 39%; Female 6%; p<0.001) and road cycling (Male 19%; Female 4%; p<0.001) were important to more men than women, whereas for gardening (Female 44%; Male 32%; p=0.001) and stretching (Female 44%; Male 16%; p<0.001) the gender preference was reversed. Overall, 24% of patients experienced severe symptoms when performing at least one of their most important activities. Older patients experienced symptoms more than younger patients (26% vs 21%; p<0.01). As a whole, 93% of patients reported that they were satisfied with their knee post-operatively. However, satisfaction with TKA decreased significantly among patients who experienced severe or debilitating symptoms during of their most important activities, (at least one activity: 78% satisfied; p<0.001; during all 3 activities: 50%; p<0.001). Discussion. The New Knee Society Scoring System provides sufficient flexibility and scope to capture the diverse lifestyles and activities of contemporary TKR patients. Data collected by this assessment tool allow surgeons and affiliated personnel to appreciate differences in the priorities of individual patients and the interplay between function, expectation, symptoms, and satisfaction after TKR. A resounding conclusion of this new multi-dimensional analysis is that a critical factor in many patients' assessment of the value of this procedure is their restored ability to perform activities that they personally consider important

Aims

Currently, there is no single, comprehensive national guideline for analgesic strategies for total joint replacement. We compared inpatient and outpatient opioid requirements following total hip arthroplasty (THA) versus total knee arthroplasty (TKA) in order to determine risk factors for increased inpatient and outpatient opioid requirements following total hip or knee arthroplasty.