Aim. Diagnosing low-grade periprosthetic joint infections (PJI) can be very challenging due to low-virulent microorganisms capable of forming biofilm. Clinical signs can be subtle and may be similar to those of aseptic failure. To minimize morbidity and mortality and to preserve quality of life, accurate diagnosis is essential. The aim of this study was to assess the performance of various diagnostic tests in diagnosing low-grade PJI.
Introduction. The accuracy of hexapod circular external fixator deformity correction is contingent on the precision of radiographic analysis during the planning stage. The aim of this study was to compare the SMART TSF (Smith and Nephew, Memphis, Tennessee) in-suite radiographic analysis methods with the traditional manual deformity analysis methods in terms of accuracy of correction. Materials and
Imageless computer navigation systems have the potential to improve acetabular cup position in total hip arthroplasty (THA), thereby reducing the risk of revision surgery. This study aimed to evaluate the accuracy of three alternate registration planes in the supine surgical position generated using imageless navigation for patients undergoing THA via the direct anterior approach (DAA). Fifty-one participants who underwent a primary THA for osteoarthritis were assessed in the supine position using both optical and inertial sensor imageless navigation systems. Three registration planes were recorded: the anterior pelvic plane (APP) method, the anterior superior iliac spines (ASIS) functional method, and the Table Tilt (TT) functional method. Post-operative acetabular cup position was assessed using CT scans and converted to radiographic inclination and anteversion. Two repeated measures analysis of variance (ANOVA) and Bland-Altman plots were used to assess errors and agreement of the final cup position. For inclination, the mean absolute error was lower using the TT functional method (2.4°±1.7°) than the ASIS functional method (2.8°±1.7°, A functional registration plane is preferable to an anatomic reference plane to measure intra-operative acetabular cup inclination and anteversion accurately. Accuracy may be further improved by registering patient location using their position on the operating table rather than anatomic landmarks, particularly if a tighter target window of ± 5° is desired.
Culture-based conventional methods are still the gold standard to identify microorganisms in hip and knee PJIs diagnosis. However, such approach presents some limitations due to prior antimicrobial treatment or the presence of unusual and fastidious organisms. Molecular techniques, in particular specific real-time and broad-range polymerase chain reaction (PCR), are available for diagnostic use in a suspected PJI. However, limited data is available on their sensitivity and specificity. This study aimed to evaluate the performance of a rapid and simple Investigational Use Only (IUO) version of the BioFire® JI multiplex PCR panel when compared to traditional microbiological procedures. Fifty-eight native synovial fluid samples were recovered from 49 patients (female n=26; male =23) who underwent one or multiple septic or aseptic revision arthroplasties of the hip (n=12) and knee (n=46). The JI panel methodology was used either on specimens freshly collected (n=6) or stored at −80°C in our Musculoskeletal Biobank (n=52). The JI panel performance was evaluated by comparison with culture reference methods. Patient's medical records were retrieved from our institutional arthroplasty registry as well as our prospectively maintained PJI infection database.Aim
Method
Currently, the gold standard for the microbiological diagnosis remains the culturing of preoperative aspirated joint fluid and intraoperative periprosthetic tissue samples, which give false negative results in about 7 % of cases. Lytic bacteriophages are viruses that specifically infect and lyse bacteria within their replication cycle. The aim of our study was to explore possibilities for the use of bacteriophage K for the detection of live Background
Aim
Objective. The efficacy and safety of tranexamic acid (TXA) on reducing blood loss and transfusion has been confirmed in primary total hip arthroplasty (THA). The main methods of administration includes intravenous, topical alone or combined use, and the most appropriated methods remains undecided. This study was aimed to compare the efficacy and safety of different methods of TXA following primary THA.
Background. Shoulder impingement syndrome (SIS) is a common debilitating condition, treated across multiple health disciplines including Orthopaedics, Physiotherapy, and Rheumatology. There is little consistency in diagnostic criteria with ‘Shoulder impingement syndrome’ being used for a broad spectrum of complex pathologies. We assessed patterns in diagnostic procedures for SIS across multiple disciplines.
Cementless Total Knee Arthroplasty has been developed to reduce the incidence of failure secondary to aseptic loosening, osteolysis and stress-induced osteopenia, especially in younger and more active patients. However, failures are still more common compared to cemented components, especially those involving the tibia. It is hypothesized that this is caused by incomplete contact between the tibial tray and the underlying bony surface due to: (i) inadequate flatness of the tibial osteotomy, or (ii) failure of implantation to spread the area of contact over the exposed cancellous surface. In the present study we compare the contact area developed during implantation of a cementless tray as a function of the initial flatness of the tibial osteotomy. Eight joint replacement surgeons prepared 14 cadaveric knees for cementless TKR using a standard instrumentation set (ZimmerBiomet Inc). The tibial osteotomy was created using an oscillating bone saw and a 1.27mm blade (Stryker Inc) directed by a slotted cutting guide mounted on an extramedullary rod and fixed to the tibia with pins and screws. The topography of the exposed cancellous surface was captured with a commercial laser scanner (Faro Inc, Halifax, approx. 33,000 surface points). 3D computer models of each tibial surface were generated in a CAD environment (Rapidform, Inuus). After scanning, a cementless tibial tray was implanted on the prepared tibial surface using a manual impactor. The tray-tibia constructs were dissected free of soft tissue, embedded in mounting resin, and sectioned with a diamond wafering saw. Points of bone-tray contact and interface separation were identified by stereomicroscopy and incorporated in the 3D computer models. Maps were generated depicting contacting and non-contacting areas Each model was subdivided into 7 zones for characterizing the distribution of interface contact in terms of anatomic location.Background
Method
Background. The optimal surgical treatment for osteonecrosis of the femoral head has yet to be elucidated. To evaluate the role of femoral fixation techniques in hip resurfacing, we present a comparison of the results for two consecutive groups: Group 1 (75 hips) received hybrid hip resurfacing implants with a cemented femoral component; Group 2 (103 hips) received uncemented femoral components. Both groups received uncemented acetabular components.
Introduction. A recent meta-analysis published in the British Medical Journal suggested an increased risk of infection, but none of the studies were large enough to reach statistical significance. A prospective, randomised trial was designed at our institution to investigate the wound healing and complications related to surgery following fracture neck of femur in the elderly. Objectives. The primary aim was to compare the wound problems and infection following two different methods of skin closure: Subcuticular monocryl suture to metal clips for closure of skin. The secondary aim was to look at the duration of surgery after both types of closure. We received ethical approval for this study. We screened and recruited all eligible patients admitted with acute hip fracture undergoing hemi-arthroplasty or dynamic hip screw. We recruited 541 patients in the study over the period of 3.5 years at our institution.
Introduction. Pre-clinical testing of orthopaedic devices could be improved by comparing performance with established implants with known clinical histories. Corail and Summit (DePuy Synthes, Warsaw) are femoral stems with proven survivorship of 95.1% and 98.1% at 10 years [1], which makes them good candidates as benchmarks when evaluating new stem designs. Hence, the aim of this study was to establish benchmark data relating to the primary stability of Corail and Summit stems.
To compare the performance of sonication and chemical methods (EDTA and DTT) for biofilm removal from artificial surface. In vitro a mature biofilms of Aim
Method
Background. Humeral retroversion is variable among individuals, and there are several measurement methods. This study was conducted to compare the concordance and reliability between the standard method and 5 other measurement methods on Twodimensional (2D) computed tomography (CT) scans.
Introduction. 11%–19% of patients are unsatisfied with outcomes from Total Knee Arthroplasty (TKA). This may be due to problems of alignment or soft-tissue balancing. In TKA, often a neutral mechanical axis is established followed by soft tissue releases to balance and match the flexion/extension gaps with the distal femoral and proximal tibial resections at right angles to the mechanical axis. Potential issues with establishment of soft tissue balance are due to associated structures such as bone tissue of the knee, the static (or passive) stabilizers of the joint (medial and lateral collateral ligaments, capsule, and anterior and posterior cruciate ligaments), and the dynamic (or active) stabilizers around the knee. An optimized balance among these systems is crucial to the successful outcome of a TKA. Additionally, the importance of correct femoral rotation has been well documented due to its effect on patella alignment and flexion instability, range of motion, and polyethylene wear. There are several methods used in TKA procedures to establish femoral component rotation. The more prominent ones are a conventional method of referencing to the posterior condylar axis with a standard external rotation of 3° (PCR), anterior-posterior line or “Whiteside's line” (AP axis), transepicondylar axis (TEA) (Figure 1), and the gap balancing technique, however, it is not yet clear, which method is superior for femoral rotational component alignment. In the current study, we sought to investigate an alternative method based on soft-tissue, dynamic knee balancing (DKB) while using an alternative analysis approach. DKB dictates femoral component rotation on the basis of ligament balance and force measures. DKB has become more prominent in TKA surgeries. While retaining ligament balance in TKA, it is possible that this technique also leads to higher precision of rotational alignment to the anatomical axis. The primary objective of this study was to compare efficiency of DKB versus other methods for rotational implant alignment based on post-surgery computed tomography (CT).
Traditional use of tourniquets and reinfusion drains in total knee replacement (TKR) has recently been challenged. Many studies have challenged the benefits of their use. Our aim was to compare the outcomes of three different blood management techniques in primary TKR. We conducted a prospective randomised study of 87 patients with a mean age of 71 years. All patients were randomised into three groups: Group A (29 patients without tourniquet and drain), Group B (27 patients without tourniquet or drain but cell salvage system) and Group C (31 patients with the use of tourniquet and drain). The results showed no difference between the postoperative haemoglobin drop and blood transfusion rate between the groups. At day two, range of knee movements (Group A: 80.2 degree; Group B: 79.6 degree; Group C: 77.9 degree) showed no significant difference. Two Group C patients (6.4%) had postoperative thromboembolic events (one DVT, one TIA). Knee stiffness leading to readmission (Group A: 6.8%; Group B: 7.4%; Group C: 3.2%) and superficial wound problems did not reveal any significant difference. The average operative time and hospital stay were the same in all groups and there was no wound haematoma or deep infection in any groups. There was no statistical difference between the groups for any outcome measure assessed thus the use of tourniquets and drains in total knee arthroplasty are controversial and questionable. We can conclude that all techniques are safe and it is the surgeon's choice as to which they apply routinely in their clinical practice.
Introduction. The elbow is the second most common site of non prosthetic joint dislocation. Simple elbow dislocation alone contributes to 11-28% of all elbow injuries. Post-reduction treatment methods include traditional plaster of Paris (POP) immobilisation followed by physiotherapy, sling application followed by early mobilisation and rapid motion. The aim of the study was to evaluate the final outcome and cost-effectiveness of the pop and the sling groups. Study Design. Retrospective cohort study.
Background. There are limited previous findings detailed biomechanical properties following implantation with mechanical and kinematic alignment method in robotic total knee arthroplasty (TKA) during walking. The purpose of this study was to compare clinical and radiological outcomes between two groups and gait analysis of kinematic, and kinetic parameters during walking to identify difference between two alignment method in robotic total knee arthroplasty.
Stable, anatomical fixation of acetabular fractures gives the best chance of a good outcome. We performed a biomechanical study to compare fracture stability and construct stiffness of three methods of fixation of posterior wall acetabular fractures. Two-dimensional motion analysis was used to measure fracture fragment displacement and the construct stiffness for each fixation method was calculated from the force / displacement data. Following 2 cyclic loading protocols of 6000 cycles, to a maximum 1.5kN, the mean fracture displacement was 0.154mm for the rim plate model, 0.326mm for the buttress plate and 0.254mm for the spring plate model. Mean maximum displacement was significantly less for the rim plate fixation than the buttress plate (p=0.015) and spring plate fixation (p=0.02). The rim plate was the stiffest construct 10962N/mm (SD 3351.8), followed by the spring plate model 5637N/mm (SD 832.6) and the buttress plate model 4882N/mm (SD 387.3). Where possible a rim plate with inter-fragmentary lag screws should be used for isolated posterior wall fracture fixation as this is the most stable and stiffest construct. However, when this method is not possible, spring plate fixation is a safe and superior alternative to a posterior buttress plate method.
Background. There are limited previous findings detailed biomechanical properties following implantation with mechanical and kinematic alignment method in robotic total knee arthroplasty (TKA) during walking. The purpose of this study was to compare clinical and radiological outcomes between two groups and gait analysis of kinematic, and kinetic parameters during walking to identify difference between two alignment method in robotic total knee arthroplasty.
Open bone graft harvesting continues to be recognized as the gold standard of obtaining autograft in patients needing bone graft. Conventional bone graft harvesting using the iliac crest is often cited as having significant donor site morbidity and complications. Intramedullary harvesting, using a reamer irrigation aspiration system (RIA) has recently become available. We performed a retrospective case series on 16 patients, where this system was used. A single pass reaming technique to harvest autograft from the femoral canal was performed. Fluoroscopy was used to size the canal and to confirm placement of a guide wire. Bone harvest volumes, complications encountered and donor site satisfaction post operatively was assessed. Patient satisfaction was determined via telephonic interviews at regular intervals with follow-up times up to 2 years.Introduction:
Method: