Introduction. Polyetheretherketone (PEEK) has been proposed as an implant material for femoral total knee arthroplasty (TKA) components. Potential clinical advantages of PEEK over standard cobalt chrome alloys include modulus of elasticity and subsequently reduced stress shielding potentially eliminating osteolysis, thermal conduction properties allowing for a more natural soft tissue environment, and reduced weight enabling quicker quadriceps recovery. Manufacturing advantages include reduced manufacturing and sterilization time, lower cost, and improved quality control. Currently, no PEEK TKA implants exist on the market. Therefore, evaluation of mechanical properties in a pre-clinical phase is required to minimize patient risk. The objectives of this study include evaluation of implant fixation and determination of the potential for reduced stress shielding using the PEEK femoral TKA component. Methods and Materials. Experimental and computational analysis was performed to evaluate the biomechanical response of the femoral component (Freedom Knee, Maxx Orthopedics Inc., Plymouth Meeting, PA; Figure 1). Fixation strength of CoCr and PEEK components was evaluated in pull-off tests of cemented femoral components on cellular polyurethane foam blocks (Sawbones, Vashon Island, WA). Subsequent testing investigated the cemented fixation using cadaveric distal femurs. The reconstructions were subjected to 500,000 cycles of the peak load occurring during a standardized gait cycle (ISO 14243-1). The change from CoCr to PEEK on implant fixation was studied through computational analysis of stress distributions in the cement, implant, and the cement-implant interface. Reconstructions were analyzed when subjected to standardized gait and demanding squat loads. To investigate potentially reduced stress shielding when using a PEEK component, paired cadaveric femurs were used to measure local bone strains using digital image correlation (DIC). First, standardized gait load was applied, then the left and right femurs were implanted with CoCr and PEEK components, respectively, and subjected to the same load. To verify the validity of the computational methodology, the intact and reconstructed femurs were replicated in FEA models, based on CT scans. Results. The cyclic load phase of the pull-off experiments revealed minimal migration for both CoCr and PEEK components, although after construct sectioning, debonding at the implant-cement interface was observed for the PEEK implants. During pull-off from Sawbones the ultimate failure load of the PEEK and CoCr components averaged 2552N and 3814N respectively. FEA simulations indicated that under more physiological loading, such as walking or squatting, the PEEK component had no increased risk of loss of fixation when compared to the CoCr component. Finally, the DIC experiments and FEA simulations confirmed closer resemblance of pre-operative strain distribution using the PEEK component. Discussion. The biomechanical consequences of changing implant material from CoCr to PEEK on implant fixation was studied using experimental and computational testing of cemented reconstructions. The results indicate that, although changes occur in implant fixation, the PEEK component had a fixation strength comparable to CoCr. The advantage of long term bone preservation, as the more compliant PEEK implant is able to better replicate the physiological loads occurring in the intact femur, may reduce stress shielding around the distal femur, a common clinical cause of TKA failure. For any figures or tables, please contact the authors directly

Introduction. The project of a modular, double-conicity stem is born from the need to obtain primary stability and correct osseointegration in patients with developmental hip dysplasia, or proximal femoral dysmorphisms requiring a femoral shortening osteotomy or presenting characteristics of non-adaptability to single-conicity or straight stems. Such an implant could also be employed in femoral nail failures, or lateral femoral neck fractures requiring prosthetic substitution. Aim of the study. To assess implantability of the new double-conicity stem in cadaver femurs, determining “fit and fill” and the behaviour of femoral cortical bone by means of Rx, CT and pre- and post-implantation mechanical testing. Methods. Seven double-conicity stems with anti-rotation fins were implanted in cadaver femurs of various sizes. All femurs underwent pre- and post-implantation radiological assessment for evaluation of fit and fill at the 2 levels corresponding to the 2 conicities, fins penetration, possible microfractures and stem positioning. Prior to implantation, templating was carried out to define the correct size of the stem to be implanted. Modular necks with cervico-diaphyseal angle of 125° or 135° (short or long) were implanted, to preserve the correct rotation center and femoral offset. In 2 femurs, mechanical testing was performed before and after implantation, in order to assess, by means of strain gauges, the variation of the tensional state of cortical bone under dynamic loading (gait cycle simulation). In 2 femurs, 3 cm chevron shortening osteotomies were performed and stabilized with the stem alone. Results. Implanted stems respected pre-operative planning. In the 2 cases in which shortening osteotomies were performed, the stem allowed for good meta-diaphyseal stability without the employment of fixation devices. Radiographic assessment evidenced a valid “fit and fill”. In 4 cases the stem was correctly aligned; in 2 cases it was positioned in 1° varus and in 1 case in 1° valgus. In the 2 osteotomy cases, penetration of the fins was good at the proximal level and slight distally. In the remaining 4 cases penetration at both levels ranged from slight to good. No microfractures, either intraoperative or following stress testing, were evidenced. Mechanical tests showed that stem implantation reduced deformation of the femoral cortical bone undergoing cyclic loading, in comparison with the pre-implantation situation. Conclusions. The double-conicity prosthetic stem showed good implantability, with the capacity to allow for stability in case of femoral shortening osteotomies without the use of plates or cerclage fixation. Mechanical testing also showed a correct load distribution, and a reduction of stress on femoral cortical bone in comparison with the state before implantation. Prospective clinical studies are necessary to assess efficacy and dependability from a clinical and radiographic viewpoint

With the increasing use of 3D medical imaging, it is possible to analyze 3D patient anatomy to extract features, trends and population specific shape information. This is applied to the development of ‘standard implants’ targeted to specific population groups. INTRODUCTION. Human beings are diverse in their physical makeup while implants are often designed based on some key measurements taken from the literature or a limited sampling of patient data. The different implant sizes are often scaled versions of the ‘average’ implant, although in reality, the shape of anatomy changes as a function of the size of patient. The implant designs are often developed based on a certain demographic and ethnicity and then, simply applied to others, which can result in poor design fitment [1]. Today, with the increasing use of 3D medical imaging (e.g. CT or MRI), it is possible to analyze 3D patient anatomy to extract features, trends and population specific shape information. This can be applied to the development of new ‘standard implants’ targeted to a specific population group [2]. PATIENTS & METHODS. Our population analysis was performed by creating a Statistical Shape Model (SSM) [3] of the dataset. In this study, 40 full Chinese cadaver femurs and 100 full Caucasian cadaver femurs were segmented from CT scans using Mimics®. Two different SSMs, specific to each population, were built using in-house software tools. These SSMs were validated using leave-one-out experiments, and then analyzed and compared in order to enhance the two population shape differences. RESULTS. An SSM is typically represented by an average model and a few independent modes of variation that capture most of the inherent variations in the data. Based on these main modes of variations, the shape features, e.g. length, thickness, curvature neck angle and femoral version, presenting largest variations were determined, and correlations between these features were calculated. Figure 1 represents the Caucasian and Chinese average models, and shows that while the length of these two models was significantly different, the AP and ML dimensions were similar, indicating a difference of morphology (other than a scaling) between the two populations. Figure 2 represents the first mode of variation that illustrates the variation of Chinese femur shape with size. As an example, the neck angle increases of 26° with an increase of 139 mm in femur length, indicative of the effect of changes in loading conditions on geometry as a function of size. CONCLUSION. The advantage of using more advanced statistical analyses is that the 3D data are probed in an unbiased fashion, allowing the most important parameters of variation to be determined. These analyses are thus particularly effective to compare different populations, to evaluate how well existing implant designs fit specific populations, and to highlight the design parameters that need to be adapted for good fitment of specific populations

Purpose. The Birmingham Mid-Head Resection (BMHR) is a bone-conserving, short-stem alternative to hip resurfacing for patients with compromised femoral head anatomy. It is unclear, however, if an uncemented, metaphyseal fixed stem confers a mechanical advantage to that of a traditional hip resurfacing in which the femoral prosthesis is cemented to the prepared femoral head. Thus, we aimed to determine if a metaphyseal fixed, bone preserving femoral component provided superior mechanical strength in resisting neck fracture compared to a conventional hip resurfacing arthroplasty. Method. Sixteen matched pairs of human cadaveric femurs were divided evenly between specimens receiving a traditional epiphyseal fixed hip resurfacing arthroplasty (BHR) and those receiving a metaphyseal fixed BMHR. Pre-preparation scaled digital radiographs were taken of all specimens to determine anatomical parameters as well as planned stem-shaft angles and implant sizes. A minimum of 10 degrees of relative valgus alignment was planned for all implants and the planned stem-shaft angles and implant sizes were equal between femur pairs. Prior to preparation, bone mineral density scans of the femurs were obtained. Prepared specimens were potted, positioned in single-leg stance and tested to failure using a mechanical testing machine. Load-displacement curves were used to calculate construct stiffness, failure energy and ultimate failure load. Results. Human cadaveric femur pairs were well matched for anatomic parameters and BMD with no statistically significant differences in neck-shaft angle (p=0.110), neck width (p=0.173), femoral offset (p=0.224) or neck BMD (p=0.525). There was a statistically significant difference between failure loads for femurs prepared with a BHR and those prepared with a BMHR (p<0.001). Femurs prepared with a BHR (7012 N, SD 2619) failed at an average of 1578 N (SD 865) greater than paired femora prepared with a BMHR (5434 N, SD 2297), representing a 24% increase in failure load. Both construct stiffness and failure energy were not statistically different between groups (p>0.065). Transcervical vertical shear fractures accounted for 19 of 32 failures, the remaining 11 were subcapital fractures. There were no fractures observed at the base of the femoral neck for either implant. Conclusion. A metaphyseal fixed, bone conserving femoral implant does not provide superior mechanical strength nor increased resistance to femoral neck fracture compared to a conventional hip resurfacing arthroplasty

Introduction. Although cementless press-fit femoral total knee arthroplasty (TKA) components are routinely used in clinical practice, the effect of the interference fit on primary stability is still not well understood. Intuitively, one would expect that a thicker coating and a higher surface roughness lead to a superior fixation. However, during implant insertion, a thicker coating can introduce more damage to the underlying bone, which could adversely influence the primary fixation. Therefore, in the current study, the effect of coating thickness and roughness on primary stability was investigated by measuring the micromotions at the bone-implant interface with experimental testing. Methods. A previous experimental set-up was used to test 6 pairs of human cadaveric femurs (47–60 years, 5 females) implanted with two femoral component designs with either the standard e.motion (Total Knee System, B. Braun, Germany) interference fit of 350 µm (right femurs) or a novel, thicker interference fit of 700 µm (left femurs). The specimens were placed in a MTS machine (Figure 1) and subjected to the peak loads of normal gait (1960N) and squat (1935N), based on the Orthoload dataset for Average 75. Varus/valgus moments were incorporated by applying the loads at an offset relative to the center of the implants, leading to a physiological mediolateral load distribution. Under these loads, micromotions at the implant-bone interface were measured using Digital Image Correlation (DIC) at different regions of interest (ROIs – Figure 1). In addition, DIC was used to measure opening and closing of the implant-bone interface in the same ROIs. Results. After comparing the micromotions and opening of the two implant designs, we found no significant differences between the standard and novel coating. Loading was a significant factor for both opening (P<0.0001) and micromotions (P=0.019), where the squat produced higher micromotions than gait. Opening was seen anteriorly (MA, LA), and was higher during squat. Closing was noticed distally (MD, LD), particularly during gait (Figure 2). During gait (Figure 3), the highest micromotions were found in the posterior condyles (CM, MP), followed by the medial anterior region (MA). For squat, the largest micromotions were in the anterior flange (ANT), followed by the distal regions (LD, MD). Discussion. In the current study, the primary stability of the same implant with two different coating thicknesses was evaluated. The results demonstrate that increasing the coating thickness does not automatically influence the primary stability of a femoral TKA component. This is likely due to abrasion and damage of the underlying trabecular during implant insertion, which also was observed in previous experiments. The exact relation between coating thickness or interference fit and primary implant stability still remains subject to debate. Obviously, the primary implant stability is compromised when the interference fit is too low. However, the current results suggest that there is a threshold beyond which further improvement of the fixation is not possible. The exact magnitude of this threshold is unknown, and may depend on coating characteristics and bone quality, and requires further evaluation, possibly utilizing a hybrid approach of experimental and computational techniques

An increasing use of short stem femoral components (SSA), in favour of conventional or “shaft” stems in THA has been reported. SSA components have been reported as bone conserving. Shaft stems are a proven and accepted form of treatment. FEA studies predict more physiological loading of bone with SSA. Cadaver femur studies demonstrate adequate stability for bone ingrowth, more physiological loading of the femur and reduced stress shielding with SSA. Clinical studies report improved outcomes with SSA compared to shaft stems (reduced bone loss, reduced pain, reduced intra-operative complication rate, improved early rehabilitation times and reduced overall cost). A mechanical analysis, to examine the reported improved outcomes with short stems and a rationale for the use of short stems rather than shaft stems is considered

Introduction. The number of total hip replacements (THR) increased around 3.5% by year in last decade. Osteoarthritis is the most important disease in the hip, with a prevalence of 10% in the older population (>85 years), according to the Swedish THA Register. THR have been increasing in last years, mainly in young patients between 45 to 59 years old. This type of patients needs a long term solution to prevent hip revision. Two commercial solutions for young patients, the resurfacing prosthesis and press fit one, were analysed in the present study by experimental and numerical models. Methods. Two synthetic left models of composite femur (Sawbones. ®. , model 3403), which replicates the cadaveric femur, and two composite pelvic bones were used to introduce two Comercial models of Hip resurfacing (Birmingham model) and Press-fit stem (Laffit Selft –locking stem press-fit model). The commercial hip stems were chosen according to the femurs head size (resurfacing) and the femur size to press-fit Hip stem. Then, they were introduced by an experimented surgeon. The experimental set-up was applied according to a system defined previously by Ramos et al. (2013). Numerical models were implemented by replicating the experimental tests. A 3D scanning was used to identify the stem position in each model. The properties of cortical and cancel bone and hip prosthesis were also taken into account by these models. Contact was established in the interfaces for both press-fit solutions. The femur rotates distally and Pelvic moves up and down according model changes, in order to guarantee models with the same boundary conditions. Results. The numerical models were already validated experimentally using different loading conditions. Results from numerical models, present different distribution in the two commercial solutions in comparison to intact articulation (Figure 1). The medial aspect is the most critical in the femur. The resurfacing hip presents a closer behavior than the intact femur at proximal region. The press-fit hip presents a strain reduction in proximal region, which promotes the bone loss observed in clinical cases. The changes in the contact Hip joint for commercial solutions modify strain distribution distally, in all femur aspects. The press fit solution increase the bending in medial aspect

The design of the femoral prosthesis in cementless total hip arthroplasty is known to affect the initial strains in the cortex during implantation and in the early postoperative time period. High strains have a direct influence on periprosthetic fracture. This study compares the existing ABGII stem, which is proximally coated with a grit blasted titanium surface with hydroxyapatite coating with a prototype that has a rougher titanium plasma spray proximal coating. The Australian National Joint registry results 2011 reported the ABG2 femoral component cumulative percent revision (CPR) of 6.5 (93.5% survival), which compares favourably with equivalent stems with 10 year CPR data such as the Taperloc 6.6 and Corail 7.3. Six pairs of fresh-frozen cadaveric femurs were mounted in blocks according to ISO guidelines in single leg stance setup. Five strain gauges were attached around the neck of the femur and then prepared according to routine operative techniques to accept the femoral prosthesis. Cortical strains were measured during insertion of the prosthesis with an instrumented mallet attached to an accelerometer. Subsequently, force-displacement readings were taken during cyclical loading on a servo-hydraulic machine and finally the stems were tested to failure. Our results showed significantly less strain during cyclical loading of the stem with increased surface roughness (p < 0.05). They also showed no significant differences loads/strains during impaction (p = 0.159), no significant difference in micromotion (p = 0.148) and no significant difference in load-to-failure (p = 0.37)

Introduction. Cementless total knee arthroplasty (TKA) has several advantages compared to the cemented approach, including elimination of bone cement, a quicker and easier surgical technique, and potentially a stronger long-term fixation. However, to ensure the successful long-term biological fixation between the porous implant and the bone, initial press-fit stability is of great importance. Undesired motion at the bone-implant interface may inhibit osseointegration and cause failure of biological fixation. Initial stability of a cementless femoral implant is affected by implant geometry, bone press-fit dimension, and characteristics of the porous coating. The purpose of this study was to compare the initial fixation stability of two types of porous femoral implants by quantifying the pull-out force using a paired cadaveric study design. Methods. The two types of cementless TKA femoral implants evaluated in this study had identical implant geometry but different porous coatings (Figure 1). The first type had a conventional spherical-bead coating (Type A), while the second type had an innovative irregularly-shaped-powder coating (Type B). The porous coating thickness was equivalent for both types of implants, thus the dimensional press-fit with bone was also equivalent. Three pairs of cadaveric femurs were prepared using standard TKA surgical technique, with each pair of the femurs receiving one of each porous implant type. An Instron 3366 load frame (Norwood, MA, USA) was used to pull the femoral implant out from the distal femur bone (Figure 2). The testing fixture was designed to allow free rotation between the implant and the actuator. The pullout was performed under a displacement control scheme (5 mm/min). Peak pull-out force was recorded and compared between the two implant groups. Results. Mean pull-out force for the Type B porous femoral implants (512 ± 246 N) was greater than that of the Type A porous femoral implants (310 ± 185 N), although the difference was not statistically significant (p>0.05) (Figure 3). Discussion. This paired cadaveric study showed that the innovative Type B porous coating provides equivalent and potentially greater pull-out force than the conventional Type A porous coating. Lack of statistical significance could be attributed to the limited sample size. Although pull-out testing is not a physiological loading scenario for TKA implant, it provides a relevant assessment of the implant-bone press-fit stability. With all other factors the same, the greater pull-out force observed in the Type B implants is likely related to the higher roughness and friction of the new porous coating. Previous experiments have shown that the Type B porous coating has significantly greater friction against Sawbones surface (coefficient of friction 0.89) compared to Type A porous coating (coefficient of friction 0.50), which was consistent with the findings in this study. Greater initial fixation stability is more favorable in cementless TKA as it reduces the risk of interface motion and better facilitates long-term biological fixation

Introduction. Primary stability is essential for long-term performance of cementless femoral components. There is debate as to whether collars contribute to primary stability. The results from experimental studies and finite element (FE) analysis have been variable and contradictory. Subtle differences in performance are often swamped by variation between cadaveric specimens in vitro, whereas FE studies tend to be performed on a single femur. However, FE studies have the potential to make comparisons of implant designs within the same cohort of femurs, allowing for subtle performance differences to be identified if present. This study investigates the effect of a collar on primary stability of a femoral prosthesis across a representative cohort of femurs. Materials and Methods. FE models were generated from QCT scans of eight cadaveric femurs taken from the Melbourne Femur Collection (4 male and 4 female; BMI: 18.7 – 36.8 kg.m-2; age: 59 – 80 years) which were of joint replacement age. Heterogeneous bone material properties were assigned based on the CT greyscale information. Each femur was implanted with the collared and collarless version of Corail femoral stem (DePuy, Leeds, United Kingdom). The stems were sized and positioned so that the prosthesis filled the medullary canal with minimal gap between the prosthesis and the inner boundary of the cortical bone. The peak muscle and joint contact forces associated with level gait were applied and the distal femur was rigidly fixed. The forces were scaled based on the body weight for each subject. Micromotion, as well as microstrains at the bone-prosthesis interface were measured for each subject. Paired t-test was run to compare the micromotion and the microstrains measured for the collared and collarless prosthesis. Results. There were no significant differences in micromotion (p > 0.005) and microstrains (p » 0.005) between collared and collarless prostheses. The mean of the median micromotions for the collared and the collarless prostheses were 19.4 microns and 20.5 microns, respectively. The mean of the median equivalent strains at the bone-implant interface for the collared and the collarless prostheses were 828.5 microstrains and 824.3 microstrains, respectively. The mean percentage of the area at the contact interface that experienced equivalent strains lower than 2000 microstrains was 69.9% for the collared and 70.0% for the collarless designs. The mean percentage of the contact area at the bone-prosthesis interface that experience equivalent strains greater than 7000 microstrains, the yield strain, was only 9.9% for the collared and 5.7% for the collarless designs. Discussion and conclusions. There was considerable variation across the cohort of femurs, with a factor of two difference for both micromotion and interface strain While small differences were noted between the collared and collarless prostheses implanted in the same femur, these differences were minimal and were likely to have little affects on primary stability, at least for a level gait load case. More demanding load cases may result in greater differences between collared and collarless implants. The results suggest that the addition of a collar in routine cases may not enhance the primary stability of a cementless hip stem

The Birmingham Hip Mid Head Resection (BMHR) was designed to accommodate patients with lower quality bone in the proximal half of the femoral head. It is a relatively new conservative hip implant with promising early results. Finite element modelling may provide an insight into mid-term results. A cadaveric femur was CT scanned and 3D geometry of the intact femur constructed. The correctly sized BMHR implants (with and without visual stop) were positioned and these verified by a surgeon; hence constructing the post-operative models. Walking loads were applied and contact surfaces defined. Stress analyses were performed using the finite element method and contact examined. Also, a strain-adaptive bone remodelling analysis was run using 45% gait hip loading data. Virtual DEXA images were computed and were analysed in seven regions of the bone surrounding the implants. The BMHR was found to be mechanically stable with all surfaces indicating micromotion less than the critical 150 microns. Stress distribution was similar to the intact femur, with the exception of the head-neck region where some stress/strain shielding occurs. This is mirrored in the bone remodelling results, which show some bone resorption in this region. The visual stop, which is designed to ensure that the stem is not overdriven during implantation, did not affect the stress/strain results; only on a very local scale. There is minimal data available in the literature regarding conservative hip implants and no data regarding the BMHR. This study is the first to look at the mechanical response of the bone to this implant

Purpose. Incidence of malrotation of femoral fractures after intramedullary nailing is as high as 28%. Prevention of malrotation is superior to late derotation osteotomy. The lesser trochanter (LT) profile has been in use for some time as a radiographic landmark of femoral rotation. One of the authors has previously described a linear regression model that describes the relationship of the LT to rotation. This paper aims to validate the use of this equation in predicting femoral rotation. Method. A survey was created and circulated online. Twenty images of cadaveric femurs of known rotation were chosen randomly from a large series. Thirty individuals with varying degrees of orthopaedic experience were invited to participate. Participants were asked to take measurements of the LT in a standardized fashion. Inter-observer variation for predicted rotation and the precision of predicted rotation was calculated. Results were grouped into those with the LT readily visible and those with the LT hidden by the femoral shaft. Results. A pilot study found the standard deviation for films with the LT hidden was 10.8 degrees, and only 6.0 degrees for films with the LT visible. The mean difference between the predicted and actual rotation was equally high in both groups (18.3 and 17.3 degrees respectively). Conclusion. Preliminary results found that the LT must be clearly visible to predict femoral rotation. This suggests that the surgeon should place the femur in a neutral or externally rotated position. In a favourable position most predictions were within a 6.0 degree spread, which would be sufficient to prevent a fifteen degree malrotation. Predicted rotation was however not precise enough to prevent a fifteen degree malrotation, regardless of LT visibility. The precision of predicted rotation may be improved by using a non-linear model. Such a model has recently been designed by a group of engineers at the University of Manitoba. The r squared value of the non-linear model was 0.88, in comparison to 0.78 for the linear equation. Precision may be further improved by using the contra-lateral LT for comparison

Background:. For hip prostheses, short stems allow easy insertion and reduce thigh pain risk, and are therefore suitable for Minimally Invasive Surgery. However, clinical outcome depends on sufficient initial fixation in the proximal femoral component. Revelation stems are designed to increase medullary cavity occupancy in the proximal femoral component and allow physiological load transmission within this component. Theoretically, on initial fixation of the proximal part of the stem, fixation remains unaffected by cutting the distal part of the stem. Recently, the Revelation micro MAX stem has become available. In this system, only the distal part of the stem is removed. To prepare for the introduction of this stem, we evaluated its rotational stability by installing it in the femurs of formalin-fixed cadavers. We then evaluated the time course of changes in bone density at the stem circumference and stem position by CT in the first eight patients undergoing hip arthroplasty. Subjects and Methods:. Micro MAX stems were inserted into the left femurs of one male and six female cadavers (76 to 95 years of age). A commonly used torque meter was mounted on the stem, and stem fixation was evaluated by the application of clockwise torque of 6 to 12 N-m. Further, in patients, three men and five women (age range 38–83 years, mean 67 years; two cases of femoral head necrosis, two of femoral neck fracture, and four of osteoarthritis of the hip) who underwent surgery with the micro MAX stem from July 2012 to April 2013 were evaluated at 3 weeks, and 3 and 6 months after surgery for stem insertion angle and stem subsidence by CT, and for bone density around the stem by the DEXE method. Results:. Rotational stability of the micro MAX stem in cadaveric femurs was similar to that of the conventionally used Revelation stem. In CT examination after surgery, the micro MAX stem tended to be inserted in a slightly varus position. No evidence of stem subsidence was observed in eight patients, but progression of the varus was seen in one. Bone density in the stem circumference was maintained. Discussion:. Although short stems have a number of advantages, problems with the first fixation might result in loosening. Allowing for the small number of patients and limited range of clinical conditions, our findings suggest that the rotational stability of the micro MAX stem is similar to that of the conventional stem. Postoperative CT measurement indicated that the micro MAX stem tended to be inserted in the varus position, particularly in patients with a large medullary cavity. The micro MAX stem was stable, and no decrease in bone density was seen. As with other short stems, however, care is required to avoid insertion in the varus position in patients with a large medullary cavity. Conclusion:. This investigation identified no problems in initial fixation with the micro MAX stem. Clinical outcomes with this system should be favorable

BACKGROUND. In vitro tests have shown that when a force is applied to the proximal femur within the range of directions spanned during physiological activities, the direction of principal strain vary by a very narrow angle (Cristofolini et al, 2009, J. Engng. Med.). This shows that the anatomy and the distribution of inhomogeneous and anisotropic material properties of the bone tissue make the structure of the proximal femur optimized to withstand a wide range of loading directions. The increasing use of hip resurfacing is associated with early neck fractures of the implanted femur. The aim of this study was to elucidate if such fractures could be caused by a non-physiological state of stress/strain post-implantation. While the possible role of notching at the neck-implant interface has already been elucidated, it is not know whether a resurfacing implant could make the principal strain vary in magnitude and direction in a way that could compromise integrity of the proximal femur. METHODS. The aim of this study was to measure if the direction of the principal strain in the proximal femur was affected by the presence of a resurfacing prosthesis. Seven human cadaver femurs were instrumented with 12 triaxial strain gauges to measure the magnitude and alignment of principal strains in the head-neck region. Each femur was implanted with a typical resurfacing prosthesis (BHR). All femurs were tested in vitro before and after implantation with a range of loading conditions to explore the range of loading directions during daily activity (Fig. 1). FINDINGS. Comparison of the strain distribution before and after implantation showed that: . In the natural conditions the principal tensile strain was significantly larger where the cortical bone was thinner; the compressive strain was larger where the cortical bone was thicker. This should be considered when designing a resurfacing prosthesis. The strain magnitude varied greatly between loading configurations both in the intact and implanted condition: this suggests that different loading configurations must be simulated for the preclinical validation of a resurfacing prosthesis. In the natural conditions, the direction of the principal strain varied significantly between measurement locations, but varied little between loading configurations (less than 10° when the hip force spanned a 21° cone, Fig. 2). This confirms that the anatomy and the distribution of anisotropic material properties enable the proximal femur to respond adequately to the changing direction of daily loading. In the resurfaced femurs, when the force spanned the same 21° cone, the direction of principal strain at each measurement location varied by less than 10° (Fig. 3), similar to the natural condition. In the resurfaced femurs, the direction of principal strain lied within less than 10° from the direction in the natural conditions. INTERPRETATION. Our results show that resurfacing does not disturb the alignment of principal strain in the proximal femur. In other words, the most critical directions of stress/strain after implantation stay aligned with the same direction as in the intact femur, which is the direction for which the inhomogeneous and anisotropic structure of the proximal femur is optimized

Purpose. Proper positioning of the components of a knee prosthesis for obtaining post-operative knee joint alignment is vital to obtain good and long term performance of a knee replacement. Although the reasons for failure of knee arthroplasty have not been studied in depth, the few studies that have been published claim that as much as 25% of knee replacement failures are related to malpositioning or malalignment [x]. The use of patient-matched cutting blocks is a recent development in orthopaedics. In contrast to the standard cutting blocks, they are designed to fit the individual anatomy based on 3D medical images. Thus, landmarks and reference axes can be identified with higher accuracy and precision. Moreover, stable positioning of the blocks with respect to the defined axes is easier to achieve. Both may contribute to better alignment of the components. The objective of this study was to check the accuracy of femoral component orientation in a cadaver study using specimen-matched cutting blocks in six specimens; first for a bi-compartmental replacement, and then for a tri-compartmental replacement in the same specimen. Materials and Methods. Frames with infrared reflective spherical markers were fixed to six cadaveric femurs and helical CT scans were made. A bone surface reconstruction was created and the relevant landmarks for describing alignment were marked using 3D visualisation software (Mimics). The centres of the spherical markers were also determined. Based on the geometry of the articular surface and the position of the landmarks, custom-made cutting blocks were designed. One cutting block was prepared to guide implantation of a bi-compartmental device and another one to guide implantation of the femoral component of a total knee replacement. The knee was opened and the custom-made cutting block for the bi-compartmental implant was seated onto the surface. The block was used to make the anterior cut, after which it was removed and replaced with the conventional cutting block using the same pinning holes to ensure the same axial rotational alignment. The other cuts were made using the conventional cutting block and the bi-compartmental femoral component was implanted. Afterwards, a similar procedure was used to make the extra cuts for the total knee component. The position of the components with respect to the reflective markers was measured by locating three reference points and “painting” the articular surface with a wand with reflective markers. The position of all marker spheres was continuously recorded with four infrared cameras and Nexus software. Results. Average alignment for the bi-compartmental component in transverse and frontal planes were 0.2° (standard deviation: 2.4°) and 0.4° (standard deviation: 2.8°), respectively. Average alignment for the tri-compartmental component in transverse and frontal planes were 0.6° (standard deviation: 3.2°) and 0.9° (standard deviation: 5.5°), respectively. Conclusions. The specimen matched cutting blocks, designed based on CT scan data, achieved a similar level of alignment accuracy as reported for navigation systems