The Adams-Berger reconstruction is an effective technique for treating distal radioulnar joint (DRUJ) instability. Graft preparation techniques vary amongst surgeons with insufficient evidence to support one technique over another. Our study evaluated the biomechanical properties of four graft preparation techniques. Extensor tendons were harvested from fresh frozen porcine trotters obtained from a local butcher shop and prepared in one of three configurations (n=5 per group): tendon only; tendon prepared with non-locking, running suture (2-0 FiberLoop, Arthrex, Naples, FL) spaced at 6 mm intervals; and tendon prepared with suture spaced at 12 mm intervals. A fourth configuration of suture alone was also tested. Tendons were allocated in a manner to ensure comparable average diameters amongst groups. Biomechanical testing occurred using custom jigs simulating radial and ulnar tunnels attached to a Bose Electroforce 3510 mechanical testing machine (TA Instruments). After being woven through the jigs, all tendons were sutured end-to-end with 2-0 PROLENE suture (Ethicon). Tendons then underwent a staircase cyclic loading protocol (5-25 Newtons [N] at 1 hertz [Hz] for 1000 cycles, then 5-50 N at 1 Hz for 1000 cycles, then 5-75 N at 1 Hz for 1000 cycles) until graft failure; if samples did not fail during the protocol, they were then loaded to failure. Samples were visually inspected for mode of failure after the protocol. A one-way analysis of variance was used to compare average tendon diameter; post-hac Tuhey tests were used to compare elongation and elongation rate. Survival to cyclic loading was analyzed using Kaplan-Meier survival curves with log rank. Statistical significance was set at a = 0.05. The average tendon diameter of each group was not statistically different [4.17 mm (tendon only), 4.33 mm (FiberLoop spaced 6 mm), and 4.30 mm (FiberLoop spaced 12 mm)]. The average survival of tendon augmented with FiberLoop was significantly higher than tendon only, and all groups had significantly improved survival compared to suture only. There was no difference in survival between FiberLoop spaced 6 mm and 12 mm. Elongation was significantly lower with suture compared to tendon augmented with FiberLoop spaced 6 mm. Elongation rate was significantly lower with suture compared to all groups. Modes of failure included rupture of the tendon, suture, or both at the simulated bone and suture and/or tendon interface, and elongation of the entire construct without rupture. In this biomechanical study, augmentation of porcine tendons with FiberLoop suture spaced at either 6 or 12 mm for DRUJ reconstruction significantly increased survival to a staircase cyclic loading protocol, as suture material was significantly stiffer than any of the tendon graft configurations

Soft tissue balancing remains the most subjective and most artistic of current techniques in total knee arthroplasty. The flexion gap is traditionally measured at approximately 45 degree of hip flexion and 90 degree of knee flexion on the operation table. Despite of aiming equal joint gaps or tensions in flexion and extension, influence of the thigh weight on the flexion gap has not been documented. Therefore, the purpose of this study was to examine the flexion gaps in the 90–90 degree flexed position and the traditional 45–90 degree flexed position of hip-knee joints. Thirty patients with osteoarthritic knee underwent total knee arthroplasty. After the PCL sacrifice, soft tissue releases, and bone cuts. Biomechanical properties of the soft tissue were obtained during the surgery, using the specially designed system. The system consists of two electric load cells in the tensioning device, digital output indicators, and an XY plotter. Load displacement curves were obtained in extension and in flexion. 160N was applied to open the joint gaps in the traditional 45–90 degree flexed position and the 90–90 degree flexed position of hip-knee joints. The flexion gap in the 90–90 degree flexed position of hip-knee joints was 2.1±1.2mm wider than that in the traditional 45–90 degree flexed position of hip-knee joints. The flexion gap had significant difference between the two different hip flexion angles. To avoid the influence of the thigh weight and obtain equal joint gaps or tensions in flexion and extension, the flexion gap should be checked in the 90–90 degree flexed position of hip-knee joints. Interestingly, the stiffness of curves obtained from the lateral in flexion is 1/3 lower than the other three. Therefore, it is very difficult to match these four. The effect of patellar position on soft tissue balancing in TKA is also under debate. We developed the digital tensor system to measure the load (N) and the distance (mm) of extension and flexion gaps in medial and lateral compartment separately with setting of femoral component trial. The gap load and distance in extension and flexion position of PS and CR TKA in both patella everted and reset position were measured. Thirty-four patients who underwent primary TKA for medial type osteoarthritis using medial parapatellar approach were included. The load was measured at the gap distance, which is equal to the sum of implants including polyethylene insert. In extension, there was no significant difference between the load in patella everted and reset position in both PS-TKA and CR.-TKA. In flexion, there was a significant decrease of the load, which is comparable to the increase of gap distance of approximately 2mm, by resetting the patella from eversion in PS-TKA. There was, however, no significant difference in CR-TKA by resetting the patella. There was no significant difference in the ratio of medial / lateral load in both PS-TKA and CR.-TKA. Soft tissue balancing of PS-TKA with medial parapatellar approach should be performed after resetting the patella. It is still unclear whether we can adjust these materials precisely and constantly or not

Objective. To investigate the biomechanical basis and report preliminary clinical efficacy of eccentric rotational acetabular osteotomy (ERAO) when treating developmental dysplasia of the hip (DDH). Methods. Biomechanical model of the hip joint was established on cadaveric hips. After performed ERAO on the biomechanical model, we explored the impact of this surgery on biomechanics of the hip joint. Meanwhile, we reported postoperative follow-up cases who underwent ERAO in our hospital between November 2007 to July 2012. A total of 14 patients (15 hips) were reported, including 4 males and 10 females, mean age was 30 years old. Harris hip score was defined as clinical evaluation standard and radiographic assessment was based on the measurement and further comparison of pre- and post-operative AHI (Acetabular-head index), CE angle (Center-edge angle) and Sharp angle. Results. The established biomechanical model was accord with the physiological state of normal hip joint. Postoperative stress was not statistically significant compared with the preoperative stress. Meanwhile, by the end of follow-up, 13 patients (14 hips) were followed for an average time of 26 months, thus, the follow-up rate was 92.9%. Harris hip score improved from preoperative (67.1 ± 8.7) points to (88.1 ± 7.3) points; postoperative AHI increased an average of 39.6%, CE angle increased an average of 33.2 ° and sharp angle reduced an average of 9.6 °. Conclusions. Both biomechanical study and preliminary clinical observation show that ERAO has the ability to correct the deformity of acetabulum. It enlarges the acetabular coverage of the femoral head and thus corrects the abnormal stress pattern. No bone graft is needed during the operation and postoperative rehabilitation is short, therefore, ERAO may have good curative effect when treating the DDH

Objective. To investigate the biomechanical mechanism and report preliminary clinical efficacy of eccentric rotational acetabular osteotomy (ERAO) when conduct treatment for developmental dysplasia of the hip (DDH). Methods. Biomechanical model of the hip joint was established on six female cadaveric hips embalmed by formalin and stimulate ERAO was then performed on the model. Vertical force was loaded on the cadaveric spine from 0 N to 500 N and strain value on femoral head was measured preoperatively and postoperatively when loading force on spine reached the point of 100, 200, 300, 400 and 500 N. Stress value were then calculated base on the measurements. Besides, we reported postoperative follow up cases which were underwent ERAO to treat DDH in our hospital from July 2007 to October 2014. A total of 25 patients (26 hips) were reported, including 6 males and 19 females. Age varies from 11 to 57 years old, and the average age was 31 years old. Postoperative hip function was evaluated by Harris hip score and anteroposterior X⁃ray of pelvic was taken preoperatively and postoperatively to measure the Acetabular⁃head index (AHI), CE angle and Sharp angle. Results. Preoperative stress increased when loaded on spine became larger, but postoperative stress changed its increasing trend into decreasing when the load was greater than 300 N (turning point), which showed a parabolic trend. Compared with the preoperative stress under different load varying from 100 N to 500 N, postoperative stress was not statistically significant. Meanwhile, by the end of follow up period, 18 patients (19 hips) were followed form 7 to 85 months. The average follow up time was 40months and the follow up rate was 72%. Harris hip score improved from preoperative 64.3±7.2 points to 85.6±5.3 points; postoperative AHI increased an average of 36.5%, CE angle increased an average of 33.1° and sharp angle reduced an average of 12.3°. All differences between pre and post operative indexes were statistically significant. Conclusion. ERAO has the ability to correct the deformity of acetabulum. It enlarges the acetabular coverage of the femoral head and thus reduces the pressure of weight bearing area

One in five patients remain unsatisfied due to ongoing pain and impaired mobility following total knee arthroplasty (TKA). It is important if surgeons can pre-operatively identify which patients may be at risk for poor outcomes after TKA. The purpose of this study was to determine if there is an association between pre-operative measures and post-operative outcomes in patients who underwent TKA.

This study included 28 patients (female = 12 / male = 16, age = 63.6 ± 6.9, BMI = 29.9 ± 7.4 kg/m2) with knee osteoarthritis who were scheduled to undergo TKA. All surgeries were performed by the same surgeon (GD), and a subvastus approach was performed for all patients. Patients visited the gait lab within one-month of surgery and 12 months following surgery. At the gait lab, patients completed the knee injury and osteoarthritis outcome score (KOOS), a timed up and go (TUG), and walking task. Variables of interest included the five KOOS sub-scores (symptoms, pain, activities of daily living, sport & recreation, and quality of life), completion time for the TUG, walking speed, and peak knee biomechanics variables (flexion angle, abduction moment, power absorption). A Pearson's product-moment correlation was run to assess the relationship between pre-operative measures and post-operative outcomes in the TKA patients.

Preliminary analyses showed the relationship to be linear with all variables normally distributed, as assessed by Shapiro-Wilk's test (p > .05), and there were no outliers. There were no statistically significant correlations between any of the pre-operative KOOS sub-scores and any of the post-operative biomechanical outcomes. Pre-operative TUG time had a statistically significant, moderate positive correlation with post-operative peak knee abduction moments [r(14) = .597, p < .001] and peak knee power absorption [r(14) = .498, p = .007], with pre-operative TUG time explaining 36% of the variability in peak knee abduction moment and 25% of the variability in peak knee power absorption. Pre-operative walking speed had a statistically significant, moderate negative correlation with post-operative peak knee abduction moments [r(14) = -.558, p = .002] and peak knee power absorption [r(14) = -.548, p = .003], with pre-operative walking speed explaining 31% of the variability in peak knee abduction moment and 30% of the variability in peak knee power absorption.

Patient reported outcome measures (PROMs), such as the KOOS, do indicate the TKA is generally successful at relieving pain and show an overall improvement. However, their pre-operative values do not correlate with any biomechanical indicators of post-operative success, such as peak knee abduction moment and knee power. Shorter pre-operative TUG times and faster pre-operative walking speeds were correlated with improved post-operative biomechanical outcomes. These are simple tasks surgeons can implement into their clinics to evaluate their patients. Future research should expand these findings to a larger sample size and to determine if other factors, such as surgical approach or implant design, improves patient outcomes.

Dual plate constructs have become an increasingly common fixation technique for midshaft clavicle fractures and typically involve the use of mini-fragment plates. The goal of this technique is to reduce plate prominence and implant irritation, as these are common reasons for revision surgery. However, limited biomechanical data exist for these lower-profile constructs. The study aim was to compare dual mini-fragment orthogonal plating to traditional small-fragment clavicle plates for biomechanical non-inferiority and to determine if an optimal plate configuration could be identified, using a cadaveric model.

Twenty-four cadaveric clavicles were randomized to one of six groups (n=4 per group), stratified by CT-based bone mineral content (BMC). The six different plating configurations compared were: pre-contoured superior or anterior fixation using a single 3.5-mm LC-DC plate, and four different dual-plating constructs utilizing 2.4-mm and 2.7-mm reconstruction or LC-DC plates. The clavicles were plated and then osteotomized to create an inferior butterfly fracture, which was then fixed with a single interfragmentary screw (OTA 15.2B). Axial, torsional, and bending (anterior and superior surface loading) stiffness were determined for each construct through non-destructive cyclic testing, using an MTS 858 Bionix materials testing system. This was followed by a load-to-failure test in three-point superior-surface bending. Kruskal-Wallace H and Mann-Whitney U were used to test for statistical significance.

There were no significant differences in BMC (median 7.9 g, range 4.2-13.8 g) for the six groups (p=1.000). For axial stiffness, the two dual-plate constructs with a superior 2.4-mm and anterior 2.7-mm plate (either reconstruction or LC-DC) were significantly stiffer than the other four constructs (p=0.021). For both superior and anterior bending, the superior 2.4-mm and anterior 2.7-mm plate constructs were significantly stiffer when compared to the 3.5-mm superior plate (p=0.043). In addition, a 3.5-mm plate placed anterior was a stiffer construct than a superior 3.5-mm plate (p=0.043). No significant differences were found in torsional stiffness or load-to-failure between the different constructs.

Dual plating using mini-fragment plates is biomechanically superior for fixation of midshaft clavicle fractures when compared to a single superior 3.5-mm plate and has similar biomechanical properties to a 3.5-mm plate placed anteriorly. With the exception of axial stiffness, no significant differences were found when different dual plating constructs were compared to each other. However, placing a 2.4-mm plate superiorly in combination with a 2.7-mm plate anteriorly might be the optimal construct, given the biomechanical superiority over the 3.5-mm plate placed superior.

Aim. Biomechanical models of the shoulder have been used to measure forces and glenohumeral pressures. Their results have been found to vary. The aim of this study was to produce a biomechanical model to replicate the biomechanical principles of the glenohumeral joint and to measure the centre of pressure on the glenoid through a mid-range of arm movement with an intact and a compromised rotator cuff. Method. The model consisted of anatomic saw-bones of a scapula and proximal humerus with calibrated extension springs to mimic rotator cuff muscles. Glenoid pressures were measured using pressure sensitive film. The joint was examined through a mid-range of movement with an intact rotator cuff and a supraspinatus deficiency. Results. In the normal cuff model, in neutral, the centre of pressure was in the centre of the glenoid and migrated inferiorly on abduction, rotation and 45° of flexion. The only exception to this was 90° flexion and 35° extension. Concavity compression force rose in internal/external rotation, was steady on flexion/extension but dropped on abduction. In the supraspinatus-deficient model, the centre of pressure dropped to the inferior lip in neutral and rose on any movement with extremes of flexion and abduction, resulting in subacromial impingement. Concavity compression force rose slightly on flexion and extension. On abduction, the force rose as much as three times that of the normal cuff. Discussion. The results suggest that the humeral joint reaction force rests in the centre of the glenoid and is driven inferiorly on arm movement. Loss of supraspinatus reverses this pattern and leads to impingement. These results would be in keeping with osteoarthritic patterns in vivo and may have a bearing on glenoid prosthesis design. Conclusion. The glenohumeral joint demonstrated inferior migration of the humeral reaction force on elevation of the arm. Cuff pathology leads to breakdown of this mechanism

The purpose of this study was to develop a quality appraisal tool for the assessment of laboratory basic science biomechanical studies.

Materials andScore development comprised of the following phases: item identification/development, item reduction, content/face/criterion validity, weighting, test-retest reliability and internal consistency. For item identification/development, the panel was asked to independently list criteria and factors they considered important for cadaver study and generate items that should be used to appraise cadaver study quality. For content validity, the content validity ratio (CVR) was calculated. The minimum accepted content validity index (CVI) was set to 0.85. For weighting, equal weight for each item was 6.7% [15 items]. Based on these figures the panel was asked to either upscale or downscale the weight for each item ensuring that the final sum for all items was 100%. Face validity was assessed by each panel member using a Likert scale from 1–7. Strong face validity was defined as a mean score of >5. Test-retest reliability was assessed using 10 randomly selected studies. Criterion validity was assessed using the QUACS scale as standard. Internal consistency was assessed using Cronbach's alpha.

Five items reached a CVI of 1 and 10 items a CVI of 0.875. For weighting five items reached a final weight of 10% and ten items 5%. The mean score for face validity was 5.6. Test-retest reliability ranged from 0.78–1.00 with 9 items reaching a perfect score. Criterion validity was 0.76 and considered to be strong. Cronbach's alpha was calculated to be 0.71 indicating acceptable internal consistency.

The new proposed quality score for basic science studies consists of 15 items and has been shown to be reliable, valid and of acceptable internal consistency. It is suggested that this score should be utilised when assessing basic science studies.

Neer Type-IIB lateral clavicle fractures are inherently unstable fractures with associated disruption of the coracoclavicular (CC) ligaments. A novel plating technique using a superior lateral locking plate with antero-posterior (AP) locking screws, resulting in orthogonal fixation in the lateral fragment has been designed to enhance stability. The purpose of this study was to biomechanically compare three different clavicle plating constructs.

24 fresh-frozen cadaveric shoulders were randomised into three groups (n=8 specimens). Group 1: lateral locking plate only (Medartis Aptus Superior Lateral Plate); Group 2: lateral locking plate with CC stabilisation (Nr. 2 FiberWire); and Group 3: lateral locking plate with two AP locking screws stabilising the lateral fragment. Data was analysed for gap formation after cyclic loading, construct stiffness and ultimate load to failure, defined by a marked decrease in the load displacement curve.

After 500 cycles, there was no statistically significant difference between the three groups in gap-formation (p = 0.179). Ultimate load to failure was significantly higher in Group 3 compared to Group 1 (286N vs. 167N; p = 0.022), but not to Group 2 (286N vs. 246N; p = 0.604). There were no statistically significant differences in stiffness (Group 1: 504N/mm; Group 2: 564N/mm; Group 3: 512N/mm; p = 0.712). Peri-implant fracture was the primary mode of failure for all three groups, with Group 3 demonstrating the lowest rate of peri-implant fractures (Group 1: 6/8; Group 2: 7/8, Group 3: 4/8; p = 0.243).

The lateral locking plate with orthogonal AP locking screw fixation in the lateral fragment demonstrated the greatest ultimate failure load, followed by the lateral locking plate with CC stabilization. The use of orthogonal screw fixation in the distal fragment may negate against the need for CC stabilization in these types of fractures, thus minimizing surgical dissection around the coracoid and potential complications.

Introduction

The French paradox regarding cemented femoral components has not been resolved, so we compared the mechanical behavior of a French stem, the CMK stem (Biomet, Warsaw, IN, USA), with a collarless, polished, tapered stem (CPT, Zimmer, Warsaw, IN, USA) using an original biomechanical instrument.

Individuals with multi-compartment knee osteoarthritis (KOA) frequently experience challenges in activities of daily living (ADL) such as stair ambulation. The Levitation “Tri-Compartment Offloader” (TCO) knee brace was designed to reduce pain in individuals with multicompartment KOA. This brace uses novel spring technology to reduce tibiofemoral and patellofemoral forces via reduced quadriceps forces. Information on brace utility during stair ambulation is limited. This study evaluated the effect of the TCO during stair descent in patients with multicompartment KOA by assessing knee flexion moments (KFM), quadriceps activity and pain.

Nine participants (6 male, age 61.4±8.1 yrs; BMI 30.4±4.0 kg/m2) were tested following informed consent. Participants had medial tibiofemoral and patellofemoral OA (Kellgren-Lawrence grades two to four) diagnosed by an orthopaedic surgeon.

Joint kinetics and muscle activity were evaluated during stair descent to compare three bracing conditions: 1) without brace (OFF); 2) brace in low power (LOW); and 3) brace in high power (HIGH). The brace spring engages from 60° to 120° and 15° to 120° knee flexion in LOW and HIGH, respectively. Individual brace size and fit were adjusted by a trained researcher.

Participants performed three trials of step-over-step stair descent for each bracing condition. Three-dimensional kinematics were acquired using an 8-camera motion capture system. Forty-one spherical reflective markers were attached to the skin (on each leg and pelvis segment) and 8 markers on the brace. Ground reaction forces and surface EMG from the vastus medialis (VM) and vastus lateralis (VL) were collected for the braced leg. Participants rated knee pain intensity performing the task following each bracing condition on a 10cm Visual Analog Scale ranging from “no pain” (0) to “worst imaginable pain” (100).

Resultant brace and knee flexion angles and KFM were analysed during stair contact for the braced leg. The brace moment was determined using brace torque-angle curves and was subtracted from the calculated KFM. Resultant moments were normalized to bodyweight and height. Peak KFMs were calculated for the loading response (Peak1) and push-off (Peak2) phases of support. EMG signals were normalized and analysed during stair contact using wavelet analysis. Signal intensities were summed across wavelets and time to determine muscle power.

Results were averaged across all 3 trials for each participant. Paired T-tests were used to determine differences between bracing conditions with a Bonferroni adjustment for multiple comparisons (α=0.025).

Peak KFM was significantly lower compared to OFF with the brace worn in HIGH during the push-off phase (p Table 1: Average peak knee flexion moments, quadriceps muscle power and knee pain during stair descent in 3 brace conditions (n=9).

Quadriceps activity, knee flexion moments and pain were significantly reduced with TCO brace wear during stair descent in KOA patients. These findings suggest that the TCO assists the quadriceps to reduce KFM and knee pain during stair descent. This is the first biomechanical evidence to support use of the TCO to reduce pain during an ADL that produces especially high knee forces and flexion moments.

For any figures or tables, please contact the authors directly.

To determine the biomechanical effect of increasing scaphoid malunion and scaphoid non-union on carpal kinematics during dynamic wrist motion using an active wrist motion simulator.

Seven cadaveric upper extremities underwent active wrist flexion and extension in a custom motion wrist simulator with scaphoid kinematics being captured with respect to the distal radius. A three-stage protocol of progressive simulated malunion severity was performed (intact, 10° malunion, 20° malunion) with data analyzed from 45° wrist flexion to 45° wrist extension. Scaphoid malunions were modelled by creating successive volar wedge osteotomies and fixating the resultant scaphoid fragments with 0.062 Kirshner wires. At the completion of malunion motion trials, a scaphoid non-union trial was carried out by removing surgical fixation to observe motion differences from the malunion trials. Motion of the scaphoid, lunate, capitate, and trapezium-trapezoid was recorded and analyzed using active optical trackers.

Increasing scaphoid malunion severity did not significantly affect scaphoid or trapezium-trapezoid motion (p>0.05); however, it did significantly alter lunate motion (p<0.001). Increasing malunion severity resulted in progressive lunate extension across wrist motion (Intact – Mal 10: mean dif. = 7.1° ± 1.6, p<0.05; Intact – Mal 20: mean dif. = 10.2° ± 2.0, p<0.05;) although this change was not as great as the difference seen during non-union trials (native – non-union: mean dif. = 13.8° ± 3.7, p<0.05).

In this in-vitro model, increasing scaphoid malunion severity was associated with progressive extension of the lunate in all wrist positions. The clinical significance of this motion change is yet to be elucidated, but this model serves as a basis for understanding the kinematic consequences of scaphoid malunion deformities.

Introduction

During its conception, Ilizarov advocated a fine wire tension of between 900N and 1200N for circular frame construction. Wire tension can be achieved via a tensioning device or ‘Russian tensioning’ (a fixed wire lengthening around a bolt). There is limited information on the latter technique. This study aimed to explore the tensions achieved via Russian tensioning and report the impact of a second wire on construct tension.

Biomechanical considerations are relevant to cup positioning in total hip replacement (THR) to optimise the patient-specific post-operative outcome. One goal is to place the hip centre of rotation (COR) such that parameters characterising the biomechanics of the hip joint lie within physiological ranges. Different biomechanical models have been developed and are based on exact knowledge about muscle insertion points whose positions can be estimated on the basis of bony landmarks. Therefore, accurate landmark localisation is necessary to obtain reliable and comparable parameter values. As most biomechanical considerations are limited to the frontal plane, landmark localisation relying on standardised pre-operative radiographs has been established in clinical practice. One potential drawback of this approach is that user-interactive landmark localisation in radiographs might be more error-prone and subjective than localisation in 3D images. Therefore, we investigated the possibility of increasing the reproducibility of interactive landmark localisation by providing 3D localisation techniques. As the so-called BLB score based on Blumentritt's biomechanical hip model has already been introduced into clinical practice as a criterion for cup position planning, we examined the anatomical landmarks involved in BLB score evaluation. We developed a CT-based simulation tool allowing for the generation of 3D bone surface models and standardised digitally reconstructed radiographs (DRRs). Correspondences between points in the 2D DRR and rays in the 3D bone surface model are automatically established and optionally visualised by the tool. Two modes of landmark localisation were examined: In the 2D-mode, only AP DRRs were displayed, and the users had to localise the landmarks by clicking within the DRR image. In the 3D-mode, additionally the arbitrarily rotatable bone surface models together with the aforementioned 2D/3D correspondences were visualised. The user could then choose between landmark localisation by clicking either within the DRR image or within the 3D view. In either case, the 2D landmark positions within the DRR were recorded. The participants were given both an example AP pelvis radiograph with highlighted anatomical landmarks and the following landmark descriptions from the user's manual (v2.06) of the mediCAD software (Hectec GmbH, Landshut, Germany): P4: ca. 3cm distal lesser trochanter minor (in the imagined direction of pull of the rectus femoris muscle towards the medial upper edge of the patella); P5:lateral, most proximal edge of the trochanter major; P6: most cranial edge of the sclerotic area; P7:spina iliaca anterior inferior; P8/P9:most lateral/cranial point of the wing of the ilium. (P1 and P2 are only needed to define the position of the mid-sagittal plane, and P3 is the pre-operative COR. Due to correct radiograph standardisation, we assumed this plane and P3 to be known prior to landmark localisation.). Thirteen surgeons repeated the experiments on four hips (CT datasets of two male patients). The following results were obtained (SD of relevant coordinates obtained with 2D localisation vs. SD of those obtained with 3D localisation) in the first patient (left hip: 1L; right hip: 1R) and the second patient (left hip: 2L; right hip: 2R):P4: 6.3 vs. 9.0 (1L); 6.7 vs. 5.6 (1R); 9.0 vs. 11.1 (2L); 7.1 vs. 8.6 (2R); P5: 4.4 vs. 2.8 (1L); 3.1 vs. 3.1 (1R); 4.3 vs. 2.4 (2L); 4.7 vs. 4.1 (2R); P6: 4.8 vs. 3.8 (1L); 2.9 vs. 2.8 (1R); 3.7 vs. 5.2 (2L); 6.9 vs. 3.5 (2R); P7: 12.2 vs. 6.1 (1L); 12.1 vs. 3.7 (1R); 7.6 vs. 4.6 (2L); 6.2 vs. 4.5 (2R); P8: 1.2 vs. 2.8 (1L); 2.0 vs. 2.6 (1R); 1.5 vs. 2.1 (2L); 2.0 vs. 1.6 (2R);P8: 4.1 vs. 2.1 (1L); 7.3 vs. 3.9 (1R); 1.6 vs. 2.6 (2L); 4.1 vs. 3.2 (2R). The greatest differences in reproducibility were observed in P7, which was barely distinguishable in the radiographs and, hence, showed very low reproducibility only for the 2D-mode. P4 showed low reproducibility in both modes due to its vague description and the relatively small portions of the femurs contained in the CT-scanned volume. In P9 the low reproducibility obtained with the 2D-mode might be partly explained by truncation artefacts present in the DRRs. Although our study needs to be extended to more datasets, we conclude that the availability of 3D data allows for higher landmark localisation reproducibility when compared with the conventional X-ray-based approach, which has additional drawbacks: Standardisation of X-ray imaging, which is necessary to retain comparability of biomechanical parameter values determined in different patients, is hard to achieve; specifications e.g. concerning the central beam may be met only after acquiring several radiographs. Moreover, once a 2D target cup position is defined based on the 2D biomechanical analyses, the transfer of this position into the 3D surgical site is difficult without additional 3D imaging. Hence, the use of 3D imaging and 3D landmark localisation techniques seems more promising for cup positioning based on biomechanical models, which, however, need validation

Identifying knee osteoarthritis (OA) patient phenotypes is relevant to assessing treatment efficacy, yet biomechanical variability has not been applied to phenotyping. This study aimed to identify demographic and gait related groups (clusters) among total knee arthroplasty (TKA) candidates, and examine inter-cluster differences in gait feature improvement post-TKA.

Knee OA patients scheduled for TKA underwent three-dimensional gait analysis one-week pre and one-year post-TKA, capturing lower-limb external ground reaction forces and kinematics using a force platform and optoelectronic motion capture. Principal component analysis was applied to frontal and sagittal knee angle and moment waveforms (n=135 pre-TKA, n=106 post-TKA), resulting in a new uncorrelated dataset of subject PCscores and PC vectors, describing major modes of variability throughout one gait cycle (0–100%). Demographics (age, gender, body mass index (BMI), gait speed), and gait angle and moment PCscores were standardized and assessed for outliers. One patient exceeding Tukey's outer (3IQR) fence was removed. Two-dimensional multidimensional scaling followed by k-medoids clustering was applied to scaled demographics and pre-TKA PCscores [134×15]. Number of clusters (k=2:10) were assessed by silhouette coefficients, s, and stability by Adjusted Rand Indices (ARI) of 100 data subsets. Clusters were validated by examining inter-cluster differences at baseline, and inter-cluster gait changes (PostPCscore–PrePCscore, n=105) by k-way ANOVA and Tukey's honestly significant difference (HSD) criterion.

Four (k=4) TKA candidate groups yielded optimum clustering metrics (s = 0.4, ARI=0.75). Cluster 1 was all-males (male:female=19:0) who walked with faster gait speeds (1>2,3), larger flexion angle magnitudes and stance-phase angle range (PC1 & PC4 1>2,3,4), and more flexion (PC2 1>2,3,4) and adduction moment (PC2 & PC3 1>2,3) range patterns. Cluster 1 had the most dynamic kinematics and kinetic loading/unloading range amongst the clusters, representing a higher-functioning (less “stiff”) male subset. Cluster 2 captured older (2>1,3) males (31:1) with slower gait speeds (2 4), and lower flexion angle magnitude (PC1 3 2,3) and less stiff kinematic and kinetic patterns relative to Clusters 2 and 3, representing a higher-functioning female subset. Radiographic severity did not differ between clusters (Kellgren-Lawrence Grade, p=0.9, n=102), and after removing demographics and re-clustering, gender differences remained (p < 0 .04). Pre-TKA, higher-functioning clusters (1&4) had more dynamic loading/un-loading kinetic patterns. Post-TKA, high-functioning clusters experienced less gait improvement (flexion angle PC2, 1,4 < 3, p≥0.004, flexion moment PC2, 4 < 2,3), with some sagittal range patterns decreasing postoperatively.

TKA candidates can be characterized by four clusters, differing by demographics and biomechanical severity features. Post-TKA, functional gains were cluster-specific, stiff-gait clusters experienced more improvement, while higher-functioning clusters experienced less gain and showed some decline. Results suggest the presence of cohorts who may not benefit functionally from TKA. Cluster profiling may support triaging and developing targeted OA treatment strategies, meeting individual function needs.

During revision total knee arthroplasty (rTKA), proximal tibial bone loss is frequently encountered and can result in a less-stable bone-implant fixation. A 3D printed titanium alloy (Ti6Al4V) revision augment that conforms to the irregular shape of the proximal tibia was recently developed. The purpose of this study was to evaluate the fixation stability of rTKA with this augment in comparison to conventional cemented rTKA.

Eleven pairs of thawed fresh-frozen cadaveric tibias (22 tibias) were potted in custom fixtures. Primary total knee arthroplasty (pTKA) surgery was performed on all tibias. Fixation stability testing was conducted using a three-stage eccentric loading protocol. Static eccentric (70% medial/ 30% lateral) loading of 2100 N was applied to the implants before and after subjecting them to 5×103 loading cycles of 700 N at 2 Hz using a joint motion simulator. Bone-implant micromotion was measured using a high-resolution optical system. The pTKA were removed. The proximal tibial bone defect was measured. One tibia from each pair was randomly allocated to the experimental group, and rTKA was performed with a titanium augment printed using selective laser melting. The contralateral side was assigned to the control group (revision with fully cemented stems). The three-stage eccentric loading protocol was used to test the revision TKAs. Independent t-tests were used to compare the micromotion between the two groups.

After revision TKA, the mean micromotion was 23.1μm ± 26.2μm in the control group and 12.9μm ± 22.2μm in the experimental group. There was significantly less micromotion in the experimental group (p= 0.04). Prior to revision surgery, the control and experimental group had no significant difference in primary TKA micromotion (p= 0.19) and tibial bone loss (p= 0.37).

This study suggests that early fixation stability of revision TKA with the novel 3D printed titanium augment is significantly better then the conventional fully cemented rTKA. The early press-fit fixation of the augment is likely sufficient for promoting bony ingrowth of the augment in vivo. Further studies are needed to investigate the long-term in-vivo fixation of the novel 3D printed augment.

Rotator cuff tears are the most common cause of shoulder disability, affecting 10% of the population under 60 and 40% of those aged 70 and above. Massive irreparable rotator cuff tears account for 30% of all tears and their management continues to be an orthopaedic challenge. Traditional surgical techniques, that is, tendon transfers are performed to restore shoulder motion, however, they result in varying outcomes of stability and complications. Superior capsular reconstruction (SCR) is a novel technique that has shown promise in restoring shoulder function, albeit in limited studies. To date, there has been no biomechanical comparison between these techniques. This study aims to compare three surgical techniques (SCR, latissimus dorsi tendon transfer and lower trapezius tendon transfer) for irreparable rotator cuff tears with respect to intact cuff control using a clinically relevant biomechanical outcome of rotational motion.

Eight fresh-frozen shoulder specimens with intact rotator cuffs were tested. After dissection of subcutaneous tissue and muscles, each specimen was mounted on a custom shoulder testing apparatus and physiologic loads were applied using a pulley setup. Under 2.2 Nm torque loading maximum internal and external rotation was measured at 0 and 60 degrees of glenohumeral abduction. Repeat testing was conducted after the creation of the cuff tear and subsequent to the three repair techniques. Repeated measures analysis with paired t-test comparisons using Sidak correction was performed to compare the rotational range of motion following each repair technique with respect to each specimen's intact control. P-values of 0.05 were considered significant.

At 0° abduction, internal rotation increased after the tear (intact: 39.6 ± 13.6° vs. tear: 80.5 ± 47.7°, p=0.019). Internal rotation was higher following SCR (52.7 ± 12.9°, intact - SCR 95% CI: −25.28°,-0.95°, p=0.034), trapezius transfer (74.2 ± 25.3°, intact – trapezius transfer: 95% CI: −71.1°, 1.81°, p=0.064), and latissimus transfer (83.5 ± 52.1°, intact – latissimus transfer: 95% CI: −118.3°, 30.5°, p=0.400) than in intact controls. However, internal rotation post SCR yielded the narrowest estimate range close to intact controls. At 60° abduction, internal rotation increased after the tear (intact: 38.7 ± 14.4° vs. tear: 49.5 ± 13°, p=0.005). Internal rotation post SCR did not differ significantly from intact controls (SCR: 49.3 ± 10.1°, intact – SCR: 95% CI: −28°, 6.91°, p=0.38). Trapezius transfer showed a trend toward significantly higher internal rotation (65.7 ± 21.1°, intact – trapezius transfer: 95% CI: −55.7°, 1.7°, p=0.067), while latissimus transfer yielded widely variable rotation angle (65.7 ± 38°, intact – latissimus transfer: 95% CI: −85.9°, 31.9°, p=0.68). There were no significant differences in external rotation for any technique at 0° or 60° abduction.

Preliminary evaluation in this cadaveric biomechanical study provides positive evidence in support of use of SCR as a less morbid surgical option than tendon transfers. The cadaveric nature of this study limits the understanding of the motion to post-operative timepoint and the results herein are relevant for otherwise normal shoulders only. Further clinical evaluation is warranted to understand the long-term outcomes related to shoulder function and stability post SCR.

Anterior shoulder instability is associated with osseous defects of the glenoid and/or humeral head (Hill-Sachs lesions). These defects can contribute to the pathology of instability by engaging together. There is a need to continue to develop methods to preoperatively identify engaging Hill-Sachs lesions for determining appropriate surgical management.

The objective was to created a working moveable 3D CT model that allows the user to move the shoulder joint into various positions to assess the relationship between the Hill-Sachs lesion and the anterior glenoid rim. This technique was applied to a cohort series of 14 patients with recurrent anterior dislocation: 4 patients had undergone osteoarticular allografting of Hill-Sachs lesions and 10 control patients had undergone CT scanning to quantify bone loss but had no treatment to address bony pathology. A biomechanical analysis was performed to rotate each 3D model using local coordinate systems through a functional range using an open-source 3D animation program, Blender (Amsterdam, Netherlands). A Hill-Sachs lesion was considered “dynamically” engaging if the angle between the lesion's long axis and anterior glenoid was parallel.

In the classical vulnerable position of the shoulder (abduction=90, external rotation=0–135), none of the Hill-Sachs lesions aligned with the anterior glenoid in any of our patients (Figure 1). Therefore, we considered there to be a “low risk” of engagement in these critical positions, as the non-parallel orientation represents a lack of true articular arc mismatch and is unlikely to produce joint instability. We then expanded our search and simulated shoulder positions throughout a physiological range of motion for all groups and found that 100% of the allograft patients and 70% of the controls had positions producing alignment and were “high risk” of engagement (p = 0.18) (Table 1). We also found that the allograft group had a greater number of positions that would engage (mean 4 ± 1 positions of engagement) compared to our controls (mean 2 ± 2 positions of engagement, p = 0.06).

We developed a 3D animated paradigm to dynamically and non-invasively visualize a patient's anatomy and determine the clinical significance of a Hill-Sachs lesion using open source software and CT images. The technique demonstrated in this series of patients showed multiple shoulder positions that align the Hill-Sachs and glenoid axes that do not necessarily meet the traditional definition of engagement. Identifying all shoulder positions at risk of “engaging”, in a broader physiological range, may have critical implications towards selecting the appropriate surgical management of bony defects. We do not claim to doubt the classic conceptual definition of engagement, but we merely introduce a technique that accounts for the dynamic component of shoulder motion, and in doing so, avoid limitations of a static criteria assumed traditional definition (like size and location of lesion). Further investigations are planned and will help to further validate the clinical utility of this method.

For any figures or tables, please contact the authors directly.

The role of anconeus in elbow stability has been a long-standing debate. Anatomical and electromyographic studies have suggested a potential role as a stabilizer. However, to our knowledge, no clinical or biomechanical studies have investigated its role in improving the stability of a lateral collateral ligament (LCL) deficient elbow.

Seven cadaveric upper extremities were mounted in an elbow motion simulator in the varus position. An LCL injured model was created by sectioning of the common extensor origin, and the LCL. The anconeus tendon and its aponeurosis were sutured in a Krackow fashion and tensioned to 10N and 20N through a transosseous tunnel at its origin. Varus-valgus angles and ulnohumeral rotations were recorded using an electromagnetic tracking system during simulated active elbow flexion with the forearm pronated and supinated. During active motion, the injured model resulted in a significant increase in varus angulation (5.3°±2.9°, P=.0001 pronation, 3.5°±3.4°, P=.001 supination) and external rotation (ER) (8.6°±5.8°, P=.001 pronation, 7.1°±6.1°, P=.003 supination) of the ulnohumeral articulation compared to the control state (varus angle −2.8°±3.4° pronation, −3.3°±3.2° supination, ER angle 2.1°±5.6° pronation, 1.6°±5.8° supination).

Tensioning of the anconeus significantly decreased the varus angulation (−1.2°±4.5°, P=.006 for 10N in pronation, −3.9°±4°, P=.0001 for 20N in pronation, −4.3°±4°, P=.0001 for 10N in supination, −5.3°±4.2°, P=.0001 for 20N in supination) and ER angle (2.6°±4.5°, P=.008 for 10N in pronation, 0.3°±5°, P=.0001 for 20N in pronation, 0.1°±5.3°, P=.0001 for 10N in supination, −0.8°±5.3°, P=.0001 for 20N in supination) of the injured elbow. Comparing anconeus tensioning to the control state, there was no significant difference in varus-valgus angulation except with anconeus tensioning to 20N with the forearm in supination which resulted in less varus angulation (P=1 for 10N in pronation, P=.267 for 20N in pronation, P=.604 for 10N in supination, P=.030 for 20N in supination). Although there were statistically significant differences in ulnohumeral rotation between anconeus tensioning and the control state (except with anconeus tensioning to 10N with the forearm in pronation which was not significantly different), anconeus tensioning resulted in decreased external rotation angle compared to the control state (P=1 for 10N in pronation, P=.020 for 20N in pronation, P=.033 for 10N in supination, P=.001 for 20N in supination).

In the highly unstable varus elbow orientation, anconeus tensioning restores the in vitro stability of an LCL deficient elbow during simulated active motion with the forearm in both pronation and supination. Interestingly, there was a significant difference in varus-valgus angulation between 20N anconeus tensioning with the forearm supinated and the control state, with less varus angulation for the anconeus tensioning which suggests that loads less than 20N is sufficient to restore varus stability during active motion with the forearm supinated. Similarly, the significant difference observed in ulnohumeral rotation between anconeus tensioning and the control state suggests that lesser degrees of anconeus tensioning would be sufficient to restore the posterolateral instability of an LCL deficient elbow. These results may have several clinical implications such as a potential role for anconeus strengthening in managing symptomatic lateral elbow instability.

Purpose

Identifying knee osteoarthritis patient phenotypes is relevant to assessing treatment efficacy. Biomechanics have not been applied to phenotyping, yet features may be related to total knee arthroplasty (TKA) outcomes, an inherently mechanical surgery. This study aimed to identify biomechanical phenotypes among TKA candidates based on demographic and gait mechanic similarities, and compare objective gait improvements between phenotypes post-TKA.