Advertisement for orthosearch.org.uk
Results 1 - 20 of 39
Results per page:
The Bone & Joint Journal
Vol. 98-B, Issue 10_Supple_B | Pages 34 - 40
1 Oct 2016
Emerson RH Alnachoukati O Barrington J Ennin K

Aims

Approved by the Food and Drug Administration in 2004, the Phase III Oxford Medial Partial Knee is used to treat anteromedial osteoarthritis (AMOA) in patients with an intact anterior cruciate ligament. This unicompartmental knee arthroplasty (UKA) is relatively new in the United States, and therefore long-term American results are lacking.

Patients and Methods

This is a single surgeon, retrospective study based on prospectively collected data, analysing a consecutive series of primary UKAs using the Phase III mobile-bearing Oxford Knee and Phase III instrumentation.

Between July 2004 and December 2006, the senior author (RHE) carried out a medial UKA in 173 patients (213 knees) for anteromedial osteoarthritis or avascular necrosis (AVN).

A total of 95 patients were men and 78 were women. Their mean age at surgery was 67 years (38 to 89) and mean body mass index 29.87 kg/m2 (17 to 62).

The mean follow-up was ten years (4 to 11).


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_12 | Pages 43 - 43
23 Jun 2023
Carender CN Taunton MJ Fruth KM Pagnano MW Abdel MP
Full Access

There is a paucity of mid-term data on modular dual-mobility (MDM) constructs versus large (≥40 mm) femoral heads (LFH) in revision total hip arthroplasties (THAs). The purpose of this study was to update our prior series at 10 years, with specific emphasis on survivorships free of re-revision for dislocation, any re-revision, and dislocation. We identified 300 revision THAs performed at a single tertiary care academic institution from 2011 to 2014. Aseptic loosening of the acetabular component (n=65), dislocation (n=59), and reimplantation as part of a two-stage exchange protocol (n=57) were the most common reasons for index revision. Dual-mobility constructs were used in 124 cases, and LFH were used in 176 cases. Mean age was 66 years, mean BMI was 31 kg/m. 2. , and 45% were female. Mean follow-up was 7 years. The 10-year survivorship free of re-revision for dislocation was 97% in the MDM cohort and 91% in the LFH cohort with a significantly increased risk of re-revision for dislocation in the LFH cohort (HR 5.2; p=0.03). The 10-year survivorship free of any re-revision was 90% in the MDM cohort and 84% in the LFH cohort with a significantly increased risk of any re-revision in the LFH cohort (HR 2.5; p=0.04). The 10-year survivorship free of any dislocation was 92% in the MDM cohort and 87% in the LFH cohort. There was a trend towards an increased risk of any dislocation in the LFH cohort (HR 2.3; p=0.06). In this head-to-head comparison, revision THAs using MDM constructs had a significantly lower risk of re-revision for dislocation compared to LFH at 10 years. In addition, there was a trend towards lower risk of any dislocation. Level of Evidence: IV


Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_16 | Pages 24 - 24
19 Aug 2024
Dagneaux L Abdel MP Sierra RJ Lewallen DG Trousdale RT Berry DJ
Full Access

Angular proximal femoral deformities increase the technical complexity of primary total hip arthroplasties (THAs). The goals were to determine the long-term implant survivorship, risk factors, complications, and clinical outcomes of contemporary primary THAs in this difficult cohort. Our institutional total joint registry was used to identify 119 primary THAs performed in 109 patients with an angular proximal femoral deformity between 1997 and 2017. The deformity was related to previous femoral osteotomy in 85%, and developmental or metabolic disorders in 15%. 53% had a predominantly varus angular deformity. The mean age was 44 years, mean BMI was 29 kg/m. 2. , and 59% were female. An uncemented metaphyseal fixation stem was used in 30%, an uncemented diaphyseal fixation stem in 28%, an uncemented modular body stem with metaphyseal fixation sleeve in 24%, and a cemented stem in 18%. Simultaneous corrective femoral osteotomy was performed in 18%. Kaplan-Meier survivorships and Harris hip scores were reported. Mean follow-up was 8 years. The 10-year survivorships free of femoral loosening, aseptic femoral revision, any revision, and any reoperation were 95%, 93%, 90% and 88%, respectively. Revisions occurred in 13 hips for: aseptic femoral component loosening (3), stem fracture (2), dislocation (2), aseptic acetabular loosening (2), polyethylene liner exchange (2), and infection (2). Preoperative varus angular deformities were associated with a higher risk of any revision (HR 10, p=0.03), and simultaneous osteotomies with a higher risk of any reoperation (HR 3.6, p=0.02). Mean Harris hip scores improved from 52 preoperatively to 82 at 10 years (p<0.001). In the largest series to date of primary THAs in patients with angular proximal femoral deformities, we found a good 10-year survivorship free from any revision. Varus angular deformities, particularly those treated with a simultaneous osteotomy due to the magnitude or location of the deformity, had a higher reoperation rate. Keywords: Proximal femoral deformity; dysplasia; femoral osteotomy; survivorship; revision. Level of evidence: Level III, comparative retrospective cohort


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_14 | Pages 1 - 1
1 Nov 2021
Mallett K Trousdale R Sierra R Abdel M Berry D
Full Access

Previous work has demonstrated increased implant failure in patients with DDH compared to osteoarthritis with historic methods and implants. This study examines outcomes of modern total hip arthroplasty (THA) techniques using uncemented fixation and cross-linked PE (XLPE) bearings for DDH. A consecutive series of 879 patients with DDH who underwent primary THA with uncemented components and a XLPE bearing at a single institution between 1999 and 2016 were identified. Mean age at index arthroplasty was 51 years, with 78% females. Mean follow-up was 8 years. 5- and 10-year survivorships free of revision were 98.4% and 98%, respectively. 5- and 10-year survivorships free of reoperation for any reason were 97% and 96%, respectively. Survivorship free of acetabular revision for aseptic loosening was 99.8% at 5 and 10 years, while survivorships free of femoral revision for aseptic loosening were 99.7% at 5 years and 99.5% at 10 years. Survivorship free of reoperation for PE damage (2 liner fractures, 2 rim damage from impingement) was 99.3% at 10 years. There were no revisions for bearing surface wear or osteolysis. 13% of patients experienced complications (4% dislocation, 3.3% wound complication rate). Ten-year survivorship free of reoperation for instability was 99.2%. 8 patients developed infection requiring operation (<1%). 100 patients had a prior pelvic osteotomy (11%), which did not increase rate of complications (p=0.22) or reoperations (p=0.51). Fixation with modern uncemented implants has dramatically reduced implant loosening in patients with DDH, and the use of XLPE bearings has markedly reduced revision for PE wear/osteolysis in this young patient population, leading to dramatically improved mid/long-term survivorship compared to historic series


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_12 | Pages 36 - 36
1 Oct 2019
Bedard NA Brown TS Lewallen DG Trousdale RT Berry DJ Abdel MP
Full Access

Introduction. Many surgeons are reluctant to use a constrained liner at the time of acetabular component revision given concerns this might result in early acetabular component loosening. We hypothesized that with appropriate initial implant stabilization of highly porous acetabular components with supplemental screw fixation, constrained liners could be safely used at the time of acetabular revision. Methods. We retrospectively identified 148 revision total hip arthroplasties (THAs) where a constrained liner of one design was cemented into a newly placed highly porous acetabular component fixed with supplemental screws (mean 5 screws). Mean age at revision THA was 69 years, with 68% being female. The most common indications for revision were two-stage re-implantation (33%), recurrent dislocation (30%), and aseptic loosening (22% acetabular; 9% acetabular/femoral component). Mean follow-up was 8 years. Results. There were no failures at the bone-implant interface, and there were no revisions for aseptic loosening of the acetabular component. Furthermore, all acetabular components were bone ingrown on radiographic analysis. The 10-year survivorships free from any acetabular revision and free from any reoperation were 75% and 67%, respectively. Overall, 33 hips (22%) required revision or reoperation for infection/wound complications (n=12), dislocation (n=11), periprosthetic femur fracture (n=4), femoral loosening (n=3), and other (n=3). The 10-year survivorship free from dislocation was 84% overall, which was similar to the 85% 10-year survivorship free from dislocation for those specifically revised for instability (p=0.9). Conclusions. Implanting a constrained liner at the time of acetabular revision in high-risk patients resulted in no cases of aseptic acetabular component loosening in this large series. This is likely related to the fact that a highly porous acetabular component was utilized with a large number of supplemental screws in each case. Such information is valuable as these data favor a paradigm shift when compared to some traditionally-held tenets. For any tables or figures, please contact the authors directly


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_9 | Pages 10 - 10
1 Oct 2020
Bettencourt JW Wyles CC Osmon DR Hanssen AD Berry DJ Abdel MP
Full Access

Introduction. Septic arthritis of the native knee often results in irreversible joint damage leading to the need for a total knee arthroplasty (TKA). This study examines the mid-term risk of periprosthetic joint infection (PJI), aseptic revision, any revision, and any reoperation in primary TKAs after septic arthritis of the native knee compared to a control cohort of primary TKAs performed for osteoarthritis (OA). Methods. We retrospectively identified 215 primary TKAs performed between 1971 and 2016 at a single institution following septic arthritis of the native knee. Eighty-two percent (177 cases) were treated in a single setting, whereas a two-stage exchange arthroplasty protocol was utilized in 18% (39 cases) for ongoing or suspected active native knee septic arthritis. Each case was matched 1:1 based on age, sex, body mass index (BMI), and surgical year to a primary TKA for OA. Mean age and BMI were 63 years and 30 kg/m2, respectively. Mean follow-up was 9 years. Results. Survivorship free from any infection (inclusive of PJI and wound infections) at 10 years was 87% in the septic arthritis cohort and 98% for the OA cohort (HR=6.5, p<0.01). Survivorship free of PJI at 10 years was 90% in the septic arthritis and 99% in the OA group (HR=6; p<0.01). There was no difference in the rate of infection when TKA occurred within 5 years of a septic arthritis diagnosis compared to a diagnosis that occurred >5 years from the TKA. The survivorship free of aseptic revision at 10 years was 83% for the septic arthritis cohort and 93% for the OA cohort (HR=2.5, p<0.01). When combining the above survivorships free of aseptic and septic revisions, the survivorship free of any revision at 10 years was 78% in the septic arthritis cohort and 91% in the OA cohort (HR=3, p<0.01). The 10-year survivorship free of any reoperation was 61% in septic arthritis group and 84% in the OA group (HR=3; p<0.01). Preoperative and 2-year postoperative Knee Society scores were similar between groups (p=0.16 and p=0.19, respectively). Conclusion. There was a 6-fold increased risk of PJI in patients undergoing TKA with prior history of septic arthritis when compared to controls who had a TKA for OA, with a cumulative incidence of 9% at 10 years. Moreover, the 10-year survivorships free of aseptic revision, any revision, and any reoperation were significantly worse in the septic arthritis cohort. Summary. A history of septic arthritis prior to primary TKA allows for satisfactory clinical outcomes, but patients had increased risk of PJI, aseptic revision, any revision, and any reoperation compared to a control cohort


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_10 | Pages 101 - 101
1 May 2016
Van Der Straeten C De Smet K
Full Access

Background and aim. Since the market withdrawal of the ASR hip resurfacing in August 2010 because of a higher than expected revision rate as reported in the Australian Joint Replacement Registry (AOAJRR), metal-on-metal hip resurfacing arthroplasty (MoMHRA) has become a controversial procedure for hip replacement. Failures related to destructive adverse local tissue reactions to metal wear debris have further discredited MoMHRA. Longer term series from experienced resurfacing specialists however, demonstrated good outcomes with excellent 10-to-15-year survivorship in young and active men. These results have recently been confirmed for some MoMHRA designs in the AOAJRR. Besides, all hip replacement registries report significantly worse survivorship of total hip arthroplasty (THA) in patients under 50 compared to older ages. The aim of this study was to review MoMHRA survivorship from the national registries reporting on hip resurfacing and determine the risk factors for revision in the different registries. Methods. The latest annual reports from the AOAJRR, the National Joint Registry of England and Wales (NJR), the Swedish Hip Registry (SHR), the Finnish Arthroplasty Registry, the New Zealand Joint Registry and the Arthroplasty Registry of the Emilia-Romagna Region in Italy (RIPO) were reviewed for 10-year survivorship of MoMHRA in general and specific designs in particular. Other registries did not have enough hip resurfacing data or long term data yet. The survivorship data were compared to conventional THA in comparable age groups and determinants for success/failure such as gender, age, diagnosis, implant design and size and surgical experience were reviewed. Results. All registries showed a significant decline of the use of MoMHRA. The AOAJRR reported a cumulative revision rate of 9.5% (95%CI: 8.9–10.1%) at 10 years for all hip resurfacings. Female gender, developmental dysplasia and femoral head sizes <49mm were significant risk factors with revision rates twice as high for head sizes <49mm compared to >55mm. In males, cumulative revision rate for all MoMHRA was 6.6% at 10 years and 7.8% at 13years with no difference in the age groups. ASR had significantly higher revision rates (23.9% at 7 years) compared to other designs. The Adept and the Mitch had the lowest revision rates at 7 years (3.6%). Cumulative revision rates for 10,750 BHR (males and females pooled) were 5.0% at 7 years, 6.9% at 10years and 8.4% at 13 years. Cumulative revision rates of THA in patients <55 years was 6.0% at 10 years and 9.4% at 13 years. Similar survivorship results were found in the Finnish, Swedish, New Zealand and RIPO registry. In the SHR, 10-year survivorship of THA in patients <50 was only around 87%. In the NJR, cumulative revision rates for all MoMHRA pooled were much less favourable (13% at 10 years – 22% in patients<50) but the revision probability of ASR was 30.4% compared to 9.0% for BHR. Surgical experience was also identified as an important determinant of success/failure. Discussion. Registries are now confirming good 10-year survivorship of certain MoMHRA designs with excellent results in males. Risk factors for revision are female gender, small head size, dysplasia and certain implant designs


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_10 | Pages 20 - 20
1 Oct 2020
Engh CA Ho H Bhal V Housman LR Masonis JL Noble JW Hopper RH Su EP
Full Access

Introduction. The BIRMINGHAM HIP. ◊. Resurfacing is a metal-on-metal (MOM) hip implant system approved by the US FDA in 2006. The approval required a multicenter, prospective, post-approval study (PAS). Our purpose is to report the current minimum 10-year results. Methods. 253 patients (280 hips) had surgery between October 2006 and December 2009 at one of 5 sites. We report revisions, survivorship, EQ-5D, Harris Hip Score (HHS), radiographic findings, and metal levels including cobalt (Co) and chromium (Cr). The mean age at surgery was 51 years, 74% male, BMI 28, osteoarthritis 95%. 243 (87%) of hips have known outcome or 10-year minimum follow-up (fup). Prior to 10 years, 5 patients died, 20 hips were revised, and 37 hips did not complete 10-year fup. Results. The 10-year component survivorship is 92.9% (95% CI 89.8–96.1%). The reasons for revision were femoral neck fracture (3), femoral loosening (5), acetabular loosening (1), pseudotumor (3), osteolysis (2) and the remaining 6 for a combination of pain, noise, or metal levels. The EQ-QAL VAS improved (mean preop: 70, 1-year: 89, p<0.001) and was stable through 10 years (87, p=0.05). The HHS improved (mean preop: 57, 1-year: 96, p<0.001) and remained stable through 10 years (96, p=0.93). Radiographically, no surviving components have migrated. 4.6% (10/218) have osteolysis. The Co and Cr levels increased at 1 year (median Co preop: 0.12 ppb, 1-year: 1.5 ppb, p<0.001; Cr preop: 0.60 ppb, 1-year: 1.70 ppb, p<0.001) and remained stable through 10 years (Co 10-year: 1.29 ppb, p=0.28; Cr 10-year: 1.36 ppb, p=0.88). The number of patients with a Co or Cr >7 ppb at one and 10 years remained similar (1-year: 3.4% (7/205), 10-year: 4.4%, (9/205), p=0.61). Conclusion. This prospective, multicenter PAS demonstrated this resurfacing is safe and durable. 10-year survivorship for males less than 55 years old is 98.3% (95% CI 95.9–100%)


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 211 - 211
1 May 2011
Lazarinis S Kärrholm J Hailer N
Full Access

Background: Hydroxyapatite (HA) coating is widely used for total hip arthroplasty as it has been suggested to improve implant ingrowth and long-term stability. However, the evidence behind the use of HA in femoral stems is ambiguous. Methods: We investigated a non-cemented, tapered titanium femoral stem that was available either with or without HA coating. This stem had been used in 3,116 total hip arthroplasties (THAs) in 2,608 patients registered in the Swedish Hip Arthroplasty Register (1992–2007). Kaplan-Meier survival analysis and a Cox regression model including type of coating, age, sex, primary diagnosis, and the type of cup fixation were used to calculate adjusted risk ratios (RR) of the risk for revision for various reasons. Results: 63.7% of the stems were coated with HA, 36.3% were uncoated. It was found that the investigated HA-coated stem had an excellent 10-year survivorship of 97.7% (95% CI 96.5–98.9), and that the stem without HA coating had a 10-year survivorship of 97.6% (95% CI 96.2–99.0) when revision due to any reason was defined as the endpoint. There was no significant difference between these two groups (p> 0.05, log rank Mantel-Cox). A Cox regression model showed that the presence of HA coating did not significantly influence the risk of stem revision due to any reason (RR 1.3; 95% CI 0.7–2.4), or due to aseptic loosening (RR 1.0; 95% CI 0.3–3.4). The risk for revision due to infection, dislocation, or fracture was also not affected by the presence of HA coating. Interpretation: Our results show HA coating of this non-cemented tapered stem with excellent 10-year survivorship does not affect the risk for revision. The assumed beneficial effect of HA coating of femoral stems in total hip arthroplasty is thus questionable


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_14 | Pages 3 - 3
1 Nov 2021
Manktelow A
Full Access

The clinical success of THA is accepted, however wide variation in implant usage and outcomes is reported across the world. The Getting It Right First Time initiative in the UK has recommended increased use of cemented constructs in patients over 70. A clear clinical directive has been proposed aiming to reduce revision rates, improve outcomes and increase cost effectiveness. This study compares the outcomes of cemented, hybrid and cementless THA from a high-volume single center at long-term follow-up. A prospective database identified 1,699 cemented, 5,782 hybrid and 2,631 cementless THAs. Mean follow-up was 8.1 years, 5.3 years and 6.3 years respectively. Primary endpoint was revision for any reason. 47 (1.79%) cemented, 93 (1.60%) hybrid and 39 (1.48%) cementless THAs underwent revision. The difference in overall revision rate was statistically significant (P=0.002). Mean time to revision was 4.5 years in the cemented group, 2.1 years in the hybrid group and 2.6 years in the cementless group. 1 year survivorship was 99.2% in the cemented group, 99.0% in the hybrid group and 98.9% in the cementless group. 3 year survivorship was 98.6% in the cemented group, 98.8% in the hybrid group and 98.9% in the cementless group. At 10 years it was 97.0%, 97.6% and 97.9% respectively. (Difference not statistically significant (p=0.09). Of relevance cemented fixation showed the lowest 10-year survivorship in patients over 70, over 75 and over 80. (not statistically significant P=0.5, 0.6 and 0.47 respectively). In a high-volume center, excellent outcomes were achieved at 10 years with all three constructs. Cemented THA had the lowest survivorship compared to hybrid, then cementless fixation. Cemented fixation did not outperform cementless fixation in any age group. Surgeons should monitor their outcomes. Use of a philosophy that works best in their own hands should be supported


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_2 | Pages 11 - 11
1 Jan 2016
Liu F Gross T
Full Access

Introduction. A recent report based on the NARA database (Nordic Arthroplasty Register Association) found that the 10-year survivorship of patients under 50 with traditional total hip arthroplasty was only 83% in 14,600 cases. The purpose of this study was to compare our experience using metal-on-metal hip resurfacing arthroplasty (HRA) to treat these patients. Methods. from May 2001 to Feb 2012, a single surgeon performed 1029 metal-on-metal HRA in 855 patients younger than 50 years old. Three different implants were used in consecutive groups of patients, first the Corin hybrid HRA (182); then the Biomet hybrid HRA (306); and finally the Biomet uncemented HRA (541). The primary diagnoses were OA (707); dysplasia (125); osteonecrosis (98); post-trauma (28); Legg-Calve-Perthes (27) and others (44). The average age was 43±6 years; 74% were men; the average BMI was 27±4; mean femoral component size was 50±4 (range 40–62); the average T-score was 0±1. 37% of our patients reported a UCLA Activity level of 9 or 10 (impact sports). Six died with causes unrelated to their HRAs. The rate of follow-up was 94%. Our patients were not selected by any criteria except the surgeon's technical ability to perform an HRA. Results. There were a total 42 failures: acetabular component loosening in 15 cases (8 before two years) femoral component loosening in 9 cases; femoral neck fracture in 5 cases; adverse wear related failure (AWRF) in 4 cases; deep infection in 3 cases; recurrent dislocation in 1 case; other causes in 5 cases. With revision of any component as the end point, the Kaplan-Meier survivorship rate was 94.9% at 8 years and 92.5% at 10 years for the entire group. We compared survivorship between groups at shorter follow-up intervals to determine if results were improving. The survivorship rate at 8 years for Biomet Hybrid group was 95.8%, which was significantly better than 89.1% for the earlier Corin Hybrid group; the survivorship rate at 5 years for the latest Biomet Uncemented HRA group was 98.7%, also better than 96.5% for the prior Biomet Hybrid group. (P=0.0001). Conclusion. Metal-on-metal hip resurfacing has less than half the 10-year failure rate of THR in young patients. As HRA technology and experience improve, our data suggests that the results further improve. HRA currently meets the NICE criteria for 10-year survivorship of implants while THR doesn't in young patients. Our HRA patients are allowed unrestricted activity, while THR patients are typically restricted. AWRF (0.4%) is a minor problem that has been blown far out of proportion to its significance. Patient selection against HRA in certain subgroups (women, small bearings, history of metal allergy) may not be advisable based on our results


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_10 | Pages 3 - 3
1 Oct 2020
Wellings EP Couch CG Taunton MJ Pagnano MW Berry DJ Abdel MP
Full Access

Introduction. Patients undergoing primary total hip arthroplasty (THA) following pelvic radiation have historically had poor survivorship free of aseptic acetabular component loosening. However, several series have reported improved results with tantalum acetabular components. The purpose of this study was to assess implant survivorship, radiographic results, and clinical outcomes of contemporary, non-tantalum, porous acetabular components in the setting of prior pelvic radiation. Methods. We retrospectively reviewed 33 patients (38 hips) with prior therapeutic pelvic radiation between 2006 and 2016 who underwent primary THA. The mean overall pelvic radiation dose was 6300 cGy with a mean latency period to THA of 5 years. The most common acetabular component was Pinnacle (Depuy-Synthes) in 76%, followed by Trident (Stryker) in 8%, Tritanium (Stryker) in 8%, Trilogy (Zimmer-Biomet) in 5%, and G7 (Zimmer-Biomet) in 3%. Eighty-seven percent of cups were fixed with screws, of which the mean number used was 3. The mean age at primary THA was 74 years, 76% were male, and the mean BMI was 30 kg/m. 2. Mean follow-up was 5 years. Results. The 10-year survivorship free of revision for aseptic loosening, free of any revision, and free of any reoperation were 100%, 89%, and 89%, respectively. There were three revisions; one each for taper corrosion, recurrent dislocation, and infection. Radiographically, all cups had evidence of osteointegration and none had radiographic evidence of loosening. The mean Harris hip score improved from 50 to 84 postoperatively (p<0.0001). Conclusion. Contemporary non-tantalum porous acetabular components with supplemental screws provided excellent implant fixation in patients with prior therapeutic pelvic radiation. At 10 years, 100% of these components were free of revision for aseptic loosening and 100% were radiographically well-fixed. Summary. Contemporary non-tantalum porous uncemented acetabular cups provided 100% survivorship free from revision for aseptic loosening for patients undergoing THA following therapeutic pelvic radiation


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_9 | Pages 20 - 20
1 Oct 2020
Gazgalis A Neuwirth AL Shah R Cooper HJ Geller JA
Full Access

Introduction. Both mobile bearing and fixed bearing unicompartmental knee arthroplasty (UKA) have demonstrated clinical success. However, much debate persists about the superiority of a single design. Currently most clinical data is based on high volume centers data, however to reduce bias, we undertook a through review of retrospective national joint registries. In this study, we aim to investigate UKA implant utilization and survivorship between 2000 and 2018. Methods. Ten annual joint registry reports of various nations were reviewed. Due to the variable statistical methods of reporting implant use and survivorship we focused on three registries: Australia (AOANJRR), New Zealand (NZJR), United Kingdom (NJR) for uniformity. We evaluated UKA usage, survivorship, utilization and revision rates for each implant. Implant survivorship was reported in the registries and was compared within nations due to variation in statistical reporting. Results. UKAs accounted for 7.24–10.3% of all primary knee surgeries. The most popular implants were, in order of popularity, the Oxford (ZimmerBiomet, Warsaw IN), ZUK (Smith & Nephew, Memphis TN / LimaCorporate, Udine, Italy), Sigma HP (DePuy, Warsaw IN), Miller-Galante (ZimmerBiomet Warsaw IN), and Preservation (DePuy, Warsaw IN) models. UKA revision rates varied by nation and ranged from 8.22%–12.8%. The Sigma HP and ZUK designs had the lowest total percent revised in the registries-Australian (3.6% and 5.1%, respectively) and New Zealand (2.5% and 1.96%, respectively)-and demonstrated among the highest 10-year survivorship in the United Kingdom registry. The United Kingdom registry reports a greater number of mobile versus fixed bearing UKA undergoing revision for dislocation and/or subluxation and instability. Conclusion. Preference for implant design as well as survivorship rates varied significantly by nation. The fixed bearing ZUK and Sigma HP implants were among the highest performing implants across the three registries


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_II | Pages 115 - 115
1 Feb 2003
Squires B Ellis A Timperley J Gie G Ling R Wendover N
Full Access

The aim of this study was to determine the medium term survivorship and function of the cemented Exeter Universal Hip Replacement when used in younger patients. Since 1988 The Exeter Hip Research Unit has prospectively gathered data on all patients who have had total hip replacements at the Princess Elizabeth Orthopaedic Hospital. There were 88 Exeter Universal total hip replacements (THR) in 71 patients who were 50 years or younger at the time of surgery and whose surgery was performed at least 10 years before. 25 surgeons performed the surgery. Mean age at surgery was 43 years (range 24 to 50 years. ) 5 patients who had 7 THRs had died leaving 81 THRs for review. Patients were reviewed in clinic at an average of 11. 4 years (10 – 13 years). No patient was lost to follow up. At review, 8 hips had been revised. 5 cases were for loose cemented metal backed acetabular prosthesis. Two femoral components were revised for infection and one for aseptic loosening. Radiographs showed that a further 10 (13%) acetabular prosthesis were loose and that 3 femurs showed significant osteolysis. Overall 10-year survivorship of stem and cup from all causes was 93%. The 10-year survivorship of stem only from all causes was 98% and from aseptic loosening was 99%. The Exeter Universal Stem performs extremely well in the younger patient. However the high failure rate of the cemented metal backed Exeter acetabular component has compromised the overall results in this series


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_8 | Pages 105 - 105
1 May 2019
Berry D
Full Access

Tapered fluted grit-blasted modular stems have now become established as a successful method of femoral revision. The success of these stems is predicated on obtaining axial stability by milling the femur to a cone and then inserting the tapered prosthesis into that cone. Torsional stability is gained by flutes that cut into the diaphysis. By having modular proximal segments of different lengths, the leg length, offset, and anteversion can be adjusted after the distal stem is fixed. This maximises the chance for the stem to be driven into the canal to whatever level provides maximum stem stability. Modular fluted tapered stems have the potential benefits of being made of titanium and hence being both bone friendly and also having a modulus of elasticity closer to that of bone. They have a well-established high rate of fixation. Drawbacks include the risk of fracture of modular junctions and tapers, and difficulty of extraction. The indications for the use of these implants vary among surgeons, but the implants are suitable for use in a wide variety of bone loss categories. Non-modular fluted tapered stems also can gain excellent fixation, but are less versatile and in most practices are used for selected simpler revisions. Results from a number of institutions in North America and Europe demonstrate high rates of implant fixation. In a recently published paper from Mayo Clinic, the 10-year survivorship, free of femoral aseptic loosening revision, of a modular fluted tapered stem was 98% and the stem performed well across a wide range of bone deficiencies. The technique of implantation will be described in a video during the presentation


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_4 | Pages 25 - 25
1 Apr 2022
Evans J Salar O Whitehouse S Kassam A Howell J Wilson M Timperley J Sayers A Whitehouse M Wilton T Hubble M
Full Access

The Exeter V40 femoral stem is the most implanted stem in the NJR for primary THA. In 2004, the 44/00/125 stem was released for use in “cement-in-cement” revision cases. It has however been used ‘off-label’ as a primary stem when, for example, patient anatomy requires a smaller stem with a 44mm offset. We aimed to investigate survival of this stem in comparison to others in the range when used in primary THAs recorded in the NJR. Analyses were performed using a dataset based on that used for the 2020 NJR annual report. Our exposure was the stem; the outcome was all-cause construct revision. Crude analyses were performed using Kaplan-Meier and adjusted using Cox models. The 44/00/125 stem was directly compared to other stems in the Exeter range. We analysed 330,732 primary THAs using the Exeter V40 stem comprising 34.5% of the 958,869 THAs with complete information from the start of the NJR to 31 December 2018. The 44/00/125 stem was implanted in 2,158 primary THAs with 67.5% in female patients and a mean age of 67.8. The 10-year revision estimate for the 44/00/125 stem was 4.9% (95%CI 3.6, 6.8) and in constructs using an Exeter V40 stem was 2.8% (95%CI 2.7, 2.8). Controlling for age, sex and ASA demonstrated an increased overall hazard of revision for constructs using the 44/00/125 stem compared to constructs using other Exeter V40 femoral stems (HR 1.8 (95%CI 1.4, 2.3)). Although the revision estimate is within the NICE 10-year benchmark, survivorship of constructs using the 44/00/125 stem appears to be lower than the rest of the Exeter V40 range. Attempts to control for age, sex and ASA will not take into account confounding by indication i.e. patients with more complex anatomy who may have a higher risk of revision. Surgeons and patients should be reassured by this but should be aware of the observed increased revision estimate and use the stem according to its indications


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_21 | Pages 88 - 88
1 Dec 2016
Greidanus N Konan S Duncan C Masri B Garbuz D
Full Access

In revision total hip arthroplasty (THA), acetabular reconstruction while dealing with severe bone loss is a challenge. The porous tantalum revision acetabular shells have been in use for the past decade. Several reports have documented successful use at early to mid-term follow up. There is, however, very little literature around the long-term survival and quality of life outcome with the use of these shells. We reviewed the results of 46 acetabular revisions with Paprosky 2 and 3 acetabular bone defects reconstructed with a hemispheric, tantalum acetabular shell and multiple supplementary screws. There were 31 females. Average age at revision was 64 years (range 23–85 years). The mean and median follow up was 11 years (range 10–12 years, SD 1). Morselised femoral allograft was used in 34 hips to fill contained cavitary defectes. Bulk femoral allografting was performed in 2 hips. At a minimum follow-up of 10 (range 10–12) years, the survivorship of the porous tantalum acetabular shell, with revision of the shell as end point was 96%. The minimum 10-year survivorship with hip revision for any reason as end point was 92%. We noted excellent pain relief (mean WOMAC pain 92.6) and good functional outcome (mean WOMAC function 90.3, mean UCLA 5); and generic quality of life measures (mean SF-12 physical component 48.3; mean SF-12 mental component 56.7). Patient satisfaction with pain relief, function and return to recreational activities were noted to be excellent. Cementless acetabular revision with the tantalum acetabular shell demonstrated excellent clinical and quality of life outcomes at minimum 10-year follow-up. As far as we are aware this is the first report of minimum 10-year follow up of use of this technique for revision hip arthroplasty


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_9 | Pages 52 - 52
1 May 2016
Moon Y Park J Seo J Jang M Kim S
Full Access

Introduction. We sought to determine the 10-year survivorship of single-radius, posterior-stabilized total knee arthroplasty (TKA) in Asian patients. We also aimed to determine whether the long-term clinical and radiographic results differed between patients with and without patellar resurfacing. Materials and Methods. This retrospective study included 148 (115 patients) consecutive single-radius, posterior-stabilized TKAs. Ten-year survivorship analysis was performed using the Kaplan-Meier method with additional surgery for any reason as the end-point. Furthermore, long-term clinical and radiographic results of 109 knees (74%; 84 patients) with more than a 10-year follow-up were analyzed. Ten-year survivorship and long-term outcomes after surgery were determined, and outcomes were compared between patients with and without patellar resurfacing. Results. Cumulative survival rate of the single-radius posterior-stabilized TKA of 148 knees was 97.7% (95% confidence interval, 93.1%–99.3%) at 10 years after surgery. Three knees had additional surgery during the 10-year follow-up because of one case of instability and two periprosthetic infections. Mean postoperative Knee Society knee score and function score were 97 and 75, respectively. There was no aseptic loosening of the prosthesis, even though a non-progressive radiolucent line was found in 10 (9%) knees. There were no differences in postoperative scores and degree of patellar tilt and displacement between patients with and without patellar resurfacing. Conclusions. Single-radius, posterior-stabilized TKA showed satisfactory long-term clinical and radiographic outcomes in Asian patients regardless of patellar resurfacing, with comparable survivorship to that reported in westerners


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_12 | Pages 42 - 42
1 Oct 2018
McCalden RW Clout A Naudie DD MacDonald SJ Somerville LE
Full Access

Purpose. The success of total knee replacement (TKR) surgery can be attributed to improvements in TKR design, instrumentation, and surgical technique. Over a decade ago oxidized zirconium (OxZr) femoral components were introduced as an alternative bearing surface to cobalt-chromium (CoCr), based on strong in-vitro evidence, to improve the longevity of TKR implants. Early reports have demonstrated the clinical success of this material however no long-term comparative studies have demonstrated the superiority of OxZr implants compared to a more traditional CoCr implant. This study aims to compare long-term survivorship and outcomes in OxZr and CoCr femoral components in a single total knee design. Methods. We reviewed our institutional database to identify all patients whom underwent a TKA with a posterior stabilized OxZr femoral component with a minimum of 10 years of follow-up. These were then matched to patients whom underwent a TKA with the identical design posterior stabilized CoCr femoral component during the same time period by gender, age and BMI. All patients had their patella resurfaced. All patients were prospectively evaluated preoperatively and postoperatively at 6 weeks, 3 months, 12 months, 2 years and every 1 to 2 years thereafter. Prospectively collected clinical outcome measures included, Western Ontario and McMaster Universities osteoarthritis index (WOMAC), Short-Form 12 (SF-12) and Knee Society clinical rating scores (KSCRS). Charts and radiographs were reviewed to determine the revision rates and survivorship (both all cause and aseptic) at 10 years allowing comparison between the two cohorts. Paired analysis was performed to determine if differences existed in patient reported outcomes. Results. There were 194 OxZr TKAs identified and matched to 194 CoCr TKAs. There was no difference in average age (OxZr, 54.2 years; CoCr, 54.4 years), Gender (OxZr, 61.9% female; CoCr, 61.9% female) and average body mass index (OxZr, 35.9 kg/m2; CoCr, 36.4 kg/m2) between the two cohorts. There were no significant differences preoperatively in any of the outcome scores between the two groups (WOMAC (p=0.361), SF-12 (p=0.771) and KSCRS (p=0.161)). Both the SF12 (p=0.787) and WOMAC (p=0.454) were similar between the two groups, however the OxZr TKA cohort had superior KSCRS compared to the CoCr TKA cohort at a minimum of 10 years (173.5 vs. 159.1, p=0.002). With revision for any reason as the end point, there was no significant difference in 10-year survivorship between the two groups (OxZr and CoCr, 96.4%, p=0.898). Similarly, aseptic revisions demonstrated comparable survivorship rates at 10-year between the OxZr (98.9%) and CoCr groups (97.9%) (p=0.404). Conclusion. In this matched cohort study, both groups demonstrated similar improvements in patient reported outcomes, although the OxZr cohort had greater KSCRS scores compared to the CoCr cohort. The reason for this difference is not clear but may represent selection bias, where OxZr implants were perhaps used in more active patients. Implant survivorship, based on revision rates for all causes and/or aseptic reasons, was excellent and similar for both the OxZr and CoCr femoral components at 10 years. Therefore, with respect to implant longevity at the end of the first decade, there appears to be no clear advantage of OxZr compared to CoCr for patients with similar demographics with this specific posterior stabilized TKA design. Further follow-up into the second and third decade may be required to demonstrate if a difference does exist


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_3 | Pages 18 - 18
1 Feb 2017
Anwander H Siebenrock K Tannast M Steppacher S
Full Access

Introduction & Objective. Labral refixation has established as a standard in open or arthroscopic treatment for femoroacetabular impingement (FAI). The rationale for this refixation is to maintain the important suction seal in the hip. To date, only few short-term results are available which indicate a superior result in FAI hips with labral refixation compared to labral resection. Scientific evidence of a beneficial effect of labral refixation in the long-term follow-up is lacking. Aim of this study was to evaluate if labral refixation can improve the cumulative 10-year survivorship in hips undergoing surgical hip dislocation for FAI compared to labral resection. Methods. We performed a retrospective comparative study of 59 patients treated with surgical hip dislocation for symptomatic FAI between December 1998 and January 2003. We analyzed two matched groups: The ‘resection’ group consisted of 25 hips that were treated consistently by excision of the damaged labrum. The ‘refixation’ group consisted of 34 hips that were treated with labral reattachment. Correction of the osseous deformity (rim trimming/femoral osteochondroplasty) did not differ between the two groups. We then evaluated the clinical (Merle d'Aubigné score) and radiographical results (according to Tönnis) at a follow-up of ten years. We calculated a cumulative Kaplan-Meier survivorship curve with the following factors as endpoints: conversion to total hip arthroplasty (THA), radiographic evidence of osteoarthritis progression, or a poor clinical result (defined as Merle d'Aubigné score of less than 15). The two curves were compared using the Log-rank test. Results. Hips with labral refixation had a significantly higher survivorship (78%, 95% confidence interval [CI] 64–92%) at ten years compared to labral resection (46%, 95% CI 26–66, p=0.008). 7 (20.6%) patients in the refixation group reached an endpoint: 2 with THA; 5 with a poor clinical result, and 5 with progression of OA. 15 (60.0%) patients in the resection group reached an endpoint: 3 with THA; 12 with a poor clinical result, and 4 with progression of OA. Conclusion. This is the first study proving that labral refixation leads to significantly better results in patients 10 years after open surgical hip dislocation for FAI. It seems advisable to preserve the labrum in this patient population whenever possible