Background

Open or arthroscopic ankle fusion (AAF) is a successful operative treatment for end-stage ankle arthritis. Evidence suggest that AAFs have better outcomes. In addition to the operative technique other patient-factors can influence outcomes. The most significant complication of ankle fusion is a non-union. To better understand the risk factors related to this we undertook a retrospective investigation of primary AAFs.

Tendinopathy can commonly occur around the foot and ankle resulting in isolated rupture, debilitating pain and degenerative foot deformity. The pathophysiology and key cells involved are not fully understood. This is partly because the dense collagen matrix that surrounds relatively few resident cells limits the ability of previous techniques to identify and target those cells of interest. In this study, we apply novel single cell RNA sequencing (CITE-Seq) techniques to healthy and tendinopathic foot/ankle tendons. For the first time we have identified multiple sub-populations of cells in human tendons. These findings challenge the view that there is a single principal tendon cell type and open new avenues for further study. Healthy tendon samples were obtained from patients undergoing tendon transfer procedures; including tibialis posterior and FHL. Diseased tendon samples were obtained during debridement of intractable Achilles and peroneal tendinopathy, and during fusion of degenerative joints. Single cell RNA sequencing with surface proteomic analysis identified 10 sub-populations of human tendon derived cells. These included groups expressing genes associated with fibro-adipogenic progenitors (FAPs) as well as ITGA7+VCAM1- recently described in mouse muscle but, as yet, not human tendon. In addition we have identified previously unrecognised sub-classes of collagen type 1 associated tendon cells. Each sub-class expresses a different set of extra-cellular matrix genes suggesting they each play a unique role in maintaining the structural integrity of normal tendon. Diseased tendon harboured a greater proportion of macrophages and cytotoxic lymphocytes than healthy tendon. This inflammatory response is potentially driven by resident tendon fibroblasts which show increased expression of pro-inflammatory cytokines. Finally, identification of a previously unknown sub-population of cells found predominantly in tendinopathic tissue offers new insight into the underlying pathophysiology. Further work aims to identify novel proteins targets for possible therapeutic pathways.

Introduction

Acetabular component loosening with associated bone loss is a challenge in revision hip arthroplasty. Trabecular Metal (TM) by Zimmer Biomet has been shown to have greater implant survivorship for all-cause acetabular revision in small cohort retrospective studies. Our study aims to review outcomes of acetabular TM implants locally.

Joint registries suggest a downward trend in the use of uncemented Total Knee Replacements (TKR) since 2003, largely related to reports of early failures of uncemented tibial and patella components. Advancements in uncemented design such as trabecular metal may improve outcomes, but there is a scarcity of high-quality data from randomised trials.

319 patients <75 years of age were randomised to either cemented or uncemented TKR implanted using computer navigation. Patellae were resurfaced in all patients. Patient outcome scores, re-operations and radiographic analysis of radiolucent lines were compared.

Two year follow up was available for 287 patients (144 cemented vs 143 uncemented). There was no difference in operative time between groups, 73.7 v 71.1 mins (p= 0.08). There were no statistical differences in outcome scores at 2 years, Oxford knee score 42.5 vs 41.8 (p=0.35), International Knee Society 84.6 vs 84.0 (p=0.76), Forgotten Joint Score 66.7 vs 66.4 (p=0.91). There were two revisions, both for infection one in each group (0.33%). 13 cemented and 8 uncemented knees underwent re-operation, the majority of these being manipulation under anaesthetic (85.7%), with no difference (8.3% vs 5.3%, 95% CI -2.81% to 8.89%, p = 0.31). No difference was found in radiographic analysis at 2 years, 1 lucent line was seen in the cemented group and 3 in the uncemented group (0.67% v 2.09%, 95%CI -4.1% to 1.24%, p = 0.29).

We found no difference in clinical or radiographic outcomes between cemented and uncemented TKR including routine patella resurfacing at two years.

Early results suggest there is no difference between cemented and uncemented TKR at 2 years with reference to survivorship, patient outcomes and radiological parameters.

Background:

Avascular necrosis (AVN) of the talus is a painful condition caused by trauma, steroids, alcoholism and haematological disorders. It is difficult to treat and at present there is insufficient evidence in favour of any particular strategy. The aim of operative therapy should be to relieve symptoms, maintain the normal architecture of the talus and treat associated arthritis. Small case series have described early core decompression, retrograde tibiotalocalcaneal arthrodesies and open tibio-calcaneal arthrodesis. Open procedures risk further talar collapse by disrupting its blood supply, and tibiotalocalcanal fusion sacrifices both the ankle and subtalar joints. The hypothesis is that arthroscopic ankle fusion relieves symptoms of AVN talus while preserving the subtalar joint and preventing further collapse.

Introduction:

Vitamin D plays an important role in bone turnover. Deficiency (including borderline deficiency, or insufficiency) has a known association with fractures and has been linked to delayed or nonunion of fractures. We therefore routinely test vitamin D in cases of nonunion. Noting a high rate of vitamin D deficiency in this group, we instituted a policy to routinely screen for and treat vitamin D deficiency in both post-operative and pre-operative patients. We hypothesised that, in the post-operative patients, levels would correlate with rates of union.

Background:

Calcaneal osteotomy is an established technique in correcting hind foot deformity. Patients have traditionally received an open osteotomy through Atkins lateral approach. In order to reduce the rate of wound complications associated with the Atkins approach, a minimally invasive surgical (MIS) technique has been adopted since 2011. This uses a low-speed, high-torque burr to perform the same osteotomy under radiographic guidance. The results of the new MIS technique, including post-operative complication rates, are compared to the standard open approach.

Introduction:

TTC fusion for the salvage of failed TARs with significant bone loss using a hindfoot nail and femoral head allograft has been reported in a number of small series. We present our experience of this procedure.

Background

Evaluation of outcomes and satisfaction following hallux valgus (HV) surgery is usually retrospective and rarely uses patient-reported outcome measures (PROMs).

Introduction

Ankle replacement is now common in the UK.

In a tertiary referral NHS practice, between 1997–2011 we implanted two types of cementless mobile bearing total ankle replacements (TAR).

Objectives

The Manchester–Oxford Foot Questionnaire (MOXFQ) is a validated 16-item, patient-reported outcome measure for evaluating outcomes of foot or ankle surgery. The original development of the instrument identified three domains. This present study examined whether the three domains could legitimately be summed to provide a single summary index score.

Introduction

In 1927, Lambrinudi described a variant triple fusion for the treatment of paralytic “drop foot”. This involved closing wedge osteotomies and fusion to correct the deformities predominantly caused by Polio. The eradication of Polio has seen a shift in its use to the correction of other complex hind foot deformities. The technique has relevance in modern Orthopaedics for other neurological and degenerate conditions. There have been few published series of this technique since 1927.

We describe a series of 14 complex corrective triple arthrodeses to illustrate the power of Lambrinudi's concepts. We believe Lambrinudi's original description has relevance in terms of modern day complex hindfoot deformity correction.

Juvenile Chronic Arthritis results in the early degeneration of multiple joints with severe pain and deformity. Treatment of ankle arthritis is complex and ankle replacement is indicated because of adjacent and distant joint involvement.

Changes in armour reinforcement of military vehicles have resulted in a changed injury pattern. Injuries which would previously have resulted in amputation are now less severe, and after initial debridement and temporary fixation the foot can now be saved. New patterns of injuries are emerging often as a part of potentially survivable poly-trauma. We describe a small series of these injuries. The techniques and results of late reconstruction are presented. We also discuss specific problems of managing patients with potential contamination with unusual organisms.

The responsiveness of the Manchester–Oxford Foot Questionnaire (MOXFQ) was compared with foot/ankle-specific and generic outcome measures used to assess all surgery of the foot and ankle. We recruited 671 consecutive adult patients awaiting foot or ankle surgery, of whom 427 (63.6%) were female, with a mean age of 52.8 years (18 to 89). They independently completed the MOXFQ, Short-Form 36 (SF-36) and EuroQol (EQ-5D) questionnaires pre-operatively and at a mean of nine months (3.8 to 14.4) post-operatively. Foot/ankle surgeons assessed American Orthopaedic Foot and Ankle Society (AOFAS) scores corresponding to four foot/ankle regions. A transition item measured perceived changes in foot/ankle problems post-surgery. Of 628 eligible patients proceeding to surgery, 491 (78%) completed questionnaires and 262 (42%) received clinical assessments both pre- and post-operatively. The regions receiving surgery were: multiple/whole foot in eight (1.3%), ankle/hindfoot in 292 (46.5%), mid-foot in 21 (3.3%), hallux in 196 (31.2%), and lesser toes in 111 (17.7%). Foot/ankle-specific MOXFQ, AOFAS and EQ-5D domains produced larger effect sizes (> 0.8) than any SF-36 domains, suggesting superior responsiveness. In analyses that anchored change in scores and effect sizes to patients’ responses to a transition item about their foot/ankle problems, the MOXFQ performed well. The SF-36 and EQ-5D performed poorly. Similar analyses, conducted within foot-region based sub-groups of patients, found that the responsiveness of the MOXFQ was good compared with the AOFAS.

This evidence supports the MOXFQ’s suitability for assessing all foot and ankle surgery.

Introduction

Ankle fusion presents a difficult problem in the presence of infection, inadequate soft tissue, poor bone stock and deformity. Nonunion and infection remains a problem even with internal fixation. Ilizarov frame provides an elegant solution to the problem with stable remote fixation while allowing lengthening, deformity correction and weight bearing.

Introduction: Severe haemophilia affects 1 in 10,000 men. The ankle along with the hip and knee are commonly affected. Ankle fusion is the preferred surgery for end stage arthritis in the younger patient although debate exists as to the preferred technique. We conducted a retrospective review of the arthroscopic ankle fusions on haemophiliacs from Oxford and compared data with that of a specialist unit in London using an open technique.

Materials and Methods: We reviewed 22 ankles (22 patients) from Oxford and 10 ankles (8 patients) from London. 90% had Type A haemophilia with similar regular monthly Factor VIII usage: 17941 U/month (Oxford) compared with 17992 (London). 73% of patients in the Oxford Group and 100% of the London group had Hepatitis C and/or HIV.

Results: Union was achieved in all patients. The mean time to union in the open group was 9.1 weeks (Mode- 8 weeks, Range 7–14) compared to 12.2 weeks (Mode- 12 weeks, Range 8–24) in the arthroscopic group. Screw removal was required in 4 patients (3 arthroscopic v’s 1 open). 1 patient in the arthroscopic group suffered a pseudoaneurysm of the dorsalis pedis artery. The arthroscopic group spent less time in hospital- 5.7 days compared to 9.5. Factor VIII usage was less in the arthroscopic group- 32,882 Units compared to 40013.

Discussion: Patients of this nature should be managed in centres used to dealing with their complex needs. Arthroscopic ankle fusion in haemophiliacs is safe for these patients. Although arthroscopic fusion may take slightly longer to unite, there are benefits in terms of reduced patient stay and factor VIII requirement and therefore costs.

Acetabular bone loss is a problem in primary and revision Total Hip Joint Replacement (THJR). Impaction bone grafting is one method of dealing with this problem. We looked at the results of two surgeons who use this method at North Shore Hospital, Auckland.

A retrospective study was carried out on all patients who had acetabular impaction bone grafting carried out as part of THJR, whether primary or revision. All operations were performed by two surgeons, Mr Rob Sharp and Mr Bill Farrington. Patients were assessed in clinic at varying time intervals post grafting, and were functionally scored.

33 patients underwent impaction grafting, a total of 35 acetabular grafts. Of these the male to female ratio was 16:17, and the mean age range was 46–82 years. Average Harris hip score was 79 (Min 54 Max 95), and the average Oxford score was 39 (min 13 Max 48). There was one failure, 3 dislocations, and1 sciatic nerve palsy.

Impaction bone grafting is one method, which can be utilised to reconstruct acetabular bone loss, with the additional advantage of restoring bone stock. We found high rates of patient satisfaction, and a low failure rate.

According to the National Institute of Clinical Excellence (NICE) Guidelines, some foot and ankle patients are, by definition, at high risk of DVT/PE. Despite NICE guidance, DVT recommendations are still controversial, and are being reviewed by the BOA to be more operation and context specific.

One consultant at our institution therefore initiated a 6 week medical DVT prophylaxis regimen for all his post-operative hind–foot surgery patients who were placed in plaster. From January 2007 to February 2008 we audited 97 hind-foot patients to measure their compliance rate, complications and DVT/PE rate.

Compliance was excellent (97%) particularly with regard to Low Molecular Weight Heparin (LMWH), but only 70% had medication prescribed for the 6 weeks, and 3% developed a DVT.

Self administered LMWH is acceptable and compliance is excellent in post operative orthopaedic patients, but not necessarily effective.

Background: Total ankle replacement (TAR) has become an established surgical procedure for the management of end-stage ankle arthropathy offering an alternative to ankle fusion. Controversy exists over whether to correct concomitant hindfoot arthropathy or malalignment as a separate procedure or simultaneously with TAR. Simultaneous surgery confers the advantage of one operation and recovery period, however, many authors believe complication rates may be higher and long-term function compromised.

Method: A retrospective review of all patients, between January 2003 and January 2007, who had undergone simultaneous bony hindfoot or midfoot corrective surgery and TAR, at our institution was performed. A matched group of primary TAR patients were included as controls. Mean follow-up was 38 and 39 months respectively. Data collected included demographics and indications, details of operative procedure, and complications with outcomes assessed by patient satisfaction, range of movement, walking distance and Visual Analogue Score (VAS) for pain.

Results: The two groups were matched for age, sex, follow-up, prostheses and diagnosis. The underlying pathology was predominantly osteoarthritis. Mean VAS improved by 7.66 points in the TAR alone group and 8 points in the TAR and adjuvant surgical procedure group. There was no statistical difference in infection, delayed wound healing, malleolar fracture or re-operation rates between the two groups.

Conclusion: We believe that an experienced Foot and Ankle surgeon can perform corrective hindfoot or mid-foot surgery simultaneously with TAR without significantly compromising outcome.

In 2004, our centre has changed from the “STAR” to the “Mobility” Total Ankle Replacement device and a study was undertaken in order to ascertain if there was a learning curve to useage of this new device and perform a comparison in terms of survival, function, additional procedures and complications.

The indications were 55% osteoarthritis, 30% Rheumatoid and 8% JIA with the remainder being haemophiliac, haemochromatosis and ankylosing spondylitis.

One third of TARs in this unit are combined with additional procedures such as subtalar fusion. Only isolated TARs were considered in this study and the tourniquet time, wound problems, length of stay and known complications for the last 20 STAR TARs was compared to the first 20 Mobility TARs.

68 Mobility TARs have been implanted since Oct 2004 and survival data was collected for this entire cohort and compared to a similar number of STARs.

Results: There was no significant difference in operative time (63 vs 65 mins) between the prostheses, no difference in intra-operative complications (0), no difference in deep infections (0% ) and a minimal difference in hospital stay (4.3 vs 5.1 days) due to non-surgeon factors.

The survival curve of the mobility and STAR shows no loss of the Mobility due to revision at up to 3 years.

Clinical outcome scores will be presented.

Summary: There is no learning curve for an experienced Foot and Ankle Surgeon in changing prosthesis and no apparent effect on morbidity for the patient. All 40 TARs are in situ and functioning acceptably at up to 3 years.

The early results for this new prosthesis show no cause for concern and surveillance is ongoing.

Between 1998 and 2007, fifteen patients with haemophilia A underwent 21 ankle arthrosco-pies+/− arthroscopic cheilectomy in order to attempt symptomatic relief of arthrosis and to increase the range of motion. All patients had severe degenerative changes radiologically.

Perioperative management was shared with our local dedicated Haemophilia service and the management algorithm will be presented.

Outcome data for pain and range of motion shows only moderate benefits.

Two patients had good relief of symptoms for 6 months. Two patients however chose to return for arthroscopies to the contralateral ankle and two had arthoscopies to the same ankle.

Follow up data is not currently available for 4 patients and the rest required fusion with a median time to fusion of 1 year.

Two patients had a documented increased range of motion, but one of these patients had an increased level of pain associated with the increased mobility.

There was 1 major complication, namely an aneurysm of the tibialis anterior artery.

Two patients had recurrent bleeds following surgery requiring ongoing and prolonged factor VIII treatment.

Average patient stay was 3.1 days, range 2 to 5 days and this stay is shorter for later years than earlier years.

The post-operative requirement for extra factor VIII ranged from 4 postoperative doses to 3 weeks ongoing treatment, median 10 doses. The average cost per dose was approximately £1128, giving a median cost of £11280 per case.

In summary, this procedure seems to be expensive in terms of QALY gains and has low rates of success in terms of function and pain relief.

Introduction: In June 2006, the post-operative plaster immobilisation protocol for patients undergoing foot and ankle surgery at our institution changed from multiple plaster changes to the immediate application of a definitive reusable split synthetic cast. This study aims to assess the savings following this change in practice.

Materials and Methods: A retrospective analysis of plaster room records from June 2005 to June 2007 was performed.

The original procedure involved application of a plaster backslab following surgery, change of cast on day 1 post operatively, suture removal and plaster change at two weeks post-operation and cast removal or bivalving six weeks post-operation, following outpatient review.

The new procedure utilised a reusable cast applied in theatre which allowed suture removal and wound inspection in the community and outpatient review at six weeks without plaster change.

Results: Two hundred and twenty-two patients from 2005–6 were managed with the plaster procedure at a cost of £344.98 per patient and a total cost of £76,586.56. While 203 patients from 2006–7 were managed with the new procedure at a cost of £147.10 per patient and a total cost of £29,861.30. The net saving to the hospital of this change in practice was £197.88 per patient and £40,169.64 in total. There were no referrals back to the hospital as a consequence of this change in practice.

Discussion: Plaster changes and hospital outpatient appointments add cost to surgical procedures. This simple change in the post-operative casting of foot and ankle patients resulted in less outpatient visits and plaster changes without compromising the standard of medical care.

Conclusions: In the current political and financial climate it is important that economic efficiency, at a local level. This study demonstrates how small changes in local practice can result in significant financial savings for hospitals.

Introduction: An ideal screw for subtalar fusion would be designed such that screw thread length in the distal bone would be maximised but without distal perforation, whilst having no threads across the fusion site that would inhibit compression.

Method: Radiographs and clinical assessment of 100 patients who had undergone subtalar fusion were analysed and correlated with the presence or absence of non-union.

In addition, using the characteristics of the inserted screw as a scaleable marker, it was calculated what would have been the optimum length of screw thread in order to maximise screw thread length in the target bone whilst preventing the screw threads being across the fusion site.

Results: There is no correlation between the presence of screw threads across the fusion site and non-union.

Currently available screws have thread lengths that are either too long (breaching the fusion site) or too short for ideal fixation and we propose a different thread length to those currently available.

However, even with current screws, we found no correlation between thread length, thread positioning across the fusion site and non-union.

Introduction: Arthroscopic ankle arthrodesis is an effective treatment for end-stage arthritis.

A screw that has any thread across the fusion site can not offer any compression and may be postulated to lower the rate of fusion. Similarly, maximal screw thread in the target bone would optimise fixation.

This retrospective study calculates the ideal characteristics of a screw used for ankle arthrodesis, and assesses the correlation between the lack of compression and non-union.

Method: Fifty-one consecutive patients(102 screws) who have had arthroscopic ankle fusions were studied. Either AO(n=38) or ACE(n=64) screws were used. We calculated the screw-thread distance that crossed the talotibial(TT) or the subtalar(ST) joints on digitised images, and recorded the outcomes of the fusions.

Result: Of the 38 AO screws, only one (2.6%) had threads across the TT joint(thread-length into the joint = 1.2mm). None of the ST joints had been breached.

Of the 64 ACE screws, 8(12.5%) had threads across the TT joint, representing 7(21.9%) of all posterior screws and 1(3%) of all anterior screws in the study. The mean length of screw-threads into the TT joint was 2.1mm(range 0.53 to 4.06 mm). The ST joints were breached by 4(6.25%) screws(all posterior). The mean length of protrusion was 1.8mm(range 0.28 to 3.89mm). No screw thread crossed both TT and ST joints simultaneously.

No non-unions were recorded in either group.

Discussion: In our study the use of ACE screws for arthroscopic arthrodesis increases the risk of screw-threads breaching either the TT or ST joints when compared to the use of AO screws.

Conclusion: We conclude a thread length of 19–20mm would optimise fixation/compression. However no clinical correlation was demonstrated between reduced compression and non-union in this study.

Introduction: Lesser toe deformities which require surgery are often treated using a technique of interphalyngeal joint fusion. This procedure is an effective way of reducing the deformity and pain associated with lesser toe deformity but necessitates internal fixation until fusion is achieved. The Kirschner wire used to provide peri-operative stability is undesirable for a number of reasons, most importantly, the risk of interosseous infection and the lack of patient satisfaction due to the need for a second procedure for the wires removal. The ‘Oxford’ procedure was developed by the senior author (PHC) both in an attempt to remove the need for Kischner wire fixation and to maintain some mobility at the interphalyngeal joint.

Patients and methods: Between January and October 1994, 14 patients underwent ‘Oxford’ procedures on isolated lesser toe deformities. Their mean age was 59 at the time of surgery (range 26 – 79, 3 male and 11 female). Each patient was reviewed in November 1995 and an assessment was made of their post-operative pain levels, function, footwear, cosmetic appearance, time to return to work and any complications they had experienced. In March 2005 (ie: at least 10 years postop) an attempt was made to review these patients and make assessments of their pain in the operated toe, any subsequent surgery in that, or other toes, and the stability of the toe. In addition, an assessment was made of the patients view of the cosmetic outcome and their satisfaction levels. 12 patients were successfully contacted and reviewed.

Results: All 12 patients were satisfied with their long term results in terms of pain relief and cosmesis.

Conclusion: The ‘Oxford’ proceedure for lesser toe deformities has good long term clinical results and avoids k-wire fixation.

Introduction: We present our early results using the Stryker navigated knee system, since March 2003. There have been several papers showing an improvement in alignment of prostheses using navigation but few series have mentioned the problems of introducing this new technology.

Method: 214 consecutive operations were audited retrospectively from operation notes, discharge summaries and clinic notes.

Results: 11 surgeons performed 214 operations on 196 patients. 205 operations were primary knee joint replacements and 9 revisions. Average operation time was 149 minutes. 96% had an excellent outcome (pain free with a good range of motion), 2.6% had a moderate outcome and 1.4% had a poor outcome. 17 patients had superficial wound infections; 4 patients required an MUA for stiffness (with a good outcome); 3 DVTs (all below knee); 1 acute and 3 delayed haemarthroses; 1 temporarily unstable knee; 5 suffered prolonged pain, 1 peri-prosthetic fracture due to anterior notching of the femur requiring revision and there was 1 quads tendon rupture. There were 4 procedures abandoned, 2 because the femoral pin was unstable in osteoporotic bone and because of 2 software errors. Average range of motion was 0–110°. There was one deep infection following pyelonephritis. Average follow up has so far been 20.6 (2–104) weeks.

Conclusion: We have found that our results compare favourably with conventional techniques. We found it particularly useful for revision surgery and those patients who had intramedullary devices for previous fractures of the femur where conventional jigs could not be used.

The resurgency of ankle replacement in the last 10 years has prompted a need for effective management of failing prostheses. We present the early to mid-term results for revision surgery of 17 arthroplasties in 17 patients from our tertiary referral centre.

Between 1999 and 2004, two Consultant Foot and Ankle Surgeons revised failing ankle arthroplasties in 17 patients (age range 51–74 years). All patients were assessed with tissue cultures and histology that were harvested at the time of surgery and managed in conjunction with a specialist Bone Infection Unit.

Intraoperative frozen section was used to aid management, but usually pre-operative decisions had been made which included

one or two stage reimplantation

Many of the patients had had previous “revision surgery” such as change of meniscal components, arthroscopic debridements and excision of impingeing osteophytes.

Indications for implantation had been osteoarthritis in 59%, rheumatoid arthritis in 18% and post-trauma in 23%. Heel shift procedures to correct malalignment had been performed in 12%.

The implants comprised 15 Scandinavian Total Ankle Replacements (STAR), one Agility and one Buechel-Pappas. Three patients had fractured malleoli secondary to bone loss.

Cultures and histology confirmed the presence of infection in 24% (defined as positive histology and more than 2/6 positive cultures) with aseptic loosening in the remainder.

One infected patient underwent amputation at his request. Six non-infected patients had successful revision of two or three components, one infected patient had Ilizarov fusion and lengthening. The remainder underwent successful hindfoot fusion over a locked intramedullary nail, even in the presence of infection, with suppression to union.

Introduction Ankle fusion presents a difficult problem in the presence of infection and poor bone stock. The Ilizarov method provides stability with remote fixation and allows weight bearing.

Patients and method Fourteen consecutive patients were studied (10 males, 4 females). The mean age at onset of disease was 50 years (range 4–70). Thirteen of the patients had either clinical or radiological evidence of infection prior to ankle fusion surgery. Mean duration of problem was 52 months (range 8–372). Aetiology included traumatic arthritis in five, failed fusion in six, septic arthritis in one, infected ankle fracture non-union in one and avascular necrosis of talus in one. Local excision was followed by Ilizarov frame compression. Diagnosis of infection was based on microbiology and histology. Antibiotic treatment was continued until union. On radiological evidence of union the frame was dynamized and removed. A below-knee cast was applied for 4 weeks.

Results At a mean period of 5 months, complete ankle fusion was found in 13/14 patients. One patient who had partial fusion of the ankle had recurrence of infection requiring amputation. Complications included pin site infection, lateral impingement, deep infection, hind-foot pain and neuroma at amputation site.

Conclusion The Ilizarov ankle fusion is a reliable salvage procedure in difficult ankle problems.

Background Recurrent haemarthroses in patients with haemophilia commonly affect the ankles. It can result in haemophilic arthropathy and necessitate arthrodesis. The purpose of this report was to present the results of arthroscopic arthrodesis performed for this condition and to highlight some of the potential difficulties encountered as part of the surgical management. The operative technique is also described.

Method Between January 2001 and May 2004, eight male patients underwent nine arthroscopic arthrodeses. The mean age was 34 years (range 19–44). The patients were identified retrospectively from a surgical database and the radiographs and outpatient notes reviewed. Patients were also contacted to determine their level of satisfaction with the procedure.

Results The mean length of follow-up was 9 months (range 3–18). All patients had united both clinically and radiographically by the time of maximal follow-up and all were satisfied with the result. One patient had minor post-operative bleeding which settled spontaneously. No other significant complications were encountered. Bony cysts were observed in three patients pre-operatively and these all resolved following the attainment of union.

Conclusion Arthroscopic arthrodesis of the ankle is a safe and reliable treatment for haemophilic ankle arthropathy. The union rate is high, the complication rate is low, the risk of disease transmission from patient to staff is lessened and the post-operative rehabilitation regime, including allowing immediate weight bearing is less arduous than with traditional open procedures. Factor requirements are lessened and the length of stay is also reduced compared with open arthrodesis. Collaboration with a haematology unit is essential for a good result to be achieved.

Acetabular component loosening and pelvic osteolysis continue to be a significant clinical challenge in revision hip arthroplasty. We present results of 339 cases of acetabular reconstruction with impacted allograft.

All patients who under went acetabular reconstruction with impaction allograft between July 1995 and July 1999 were included. Clinical and radiographic data was collected prospectively.

There were 339 patients identified. Average age was 71 years. The majority were first time revisions (201) but the group includes 2nd, 3rd and 4th revisions with 34 two-stage revisions and 44 primary arthroplasties.

There were multiple surgeons with 2/3 being consultants and 1/3 fellows. Pre and post-operative clinical assessment included Oxford and Harris hip scores, and a modified Charnley score for pain, function and range of movement.

Pre-operative radiographs were classified with the Paprosky classification. Follow up radiographs were assessed for graft thickness, component migration, graft reabsorption and lucent lines.

There were 10 grade I, 205 grade II, and 103 grade III defects with 3 pelvic discontinuities. Reconstruction methods included impaction only, rim and/or medial mesh, KP plate fixation and reinforcement cages.

Follow up average was 6.1 years (4.3 – 8.4) and no patient was lost. Infection was identified in 13 patients (5 recurrent 89% eradication and 8 new 2.6%). There were 6 nerve injuries, 2 remain unresolved and 13 patients dislocated (3.8%). There have been 46 deaths in the group with 3 being peri-operative.

There have been 18 re-operations for aseptic loosening. 7 KP plates fractured, 1 cage migrated and 10 rim meshes failed.

Factors associated with aseptic loosening include use of a large rim mesh particularly with an allograft thickness of > 2cm.

We conclude that impaction allografting is a reliable method for acetabular reconstruction. Careful consideration should be given when allograft thickness will be > 2cm and a large rim mesh is required.