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The Bone & Joint Journal
Vol. 104-B, Issue 1 | Pages 112 - 119
1 Jan 2022
Pietton R Bouloussa H Langlais T Taytard J Beydon N Skalli W Vergari C Vialle R

Aims. This study addressed two questions: first, does surgical correction of an idiopathic scoliosis increase the volume of the rib cage, and second, is it possible to evaluate the change in lung function after corrective surgery for adolescent idiopathic scoliosis (AIS) using biplanar radiographs of the ribcage with 3D reconstruction?. Methods. A total of 45 patients with a thoracic AIS which needed surgical correction and fusion were included in a prospective study. All patients underwent pulmonary function testing (PFT) and low-dose biplanar radiographs both preoperatively and one year after surgery. The following measurements were recorded: forced vital capacity (FVC), slow vital capacity (SVC), and total lung capacity (TLC). Rib cage volume (RCV), maximum rib hump, main thoracic curve Cobb angle (MCCA), medial-lateral and anteroposterior diameter, and T4-T12 kyphosis were calculated from 3D reconstructions of the biplanar radiographs. Results. All spinal and thoracic measurements improved significantly after surgery (p < 0.001). RCV increased from 4.9 l (SD 1) preoperatively to 5.3 l (SD 0.9) (p < 0.001) while TLC increased from 4.1 l (SD 0.9) preoperatively to 4.3 l (SD 0.8) (p < 0.001). RCV was correlated with all functional indexes before and after correction of the deformity. Improvement in RCV was weakly correlated with correction of the mean thoracic Cobb angle (p = 0.006). The difference in TLC was significantly correlated with changes in RCV (p = 0.041). It was possible to predict postoperative TLC from the postoperative RCV. Conclusion. 3D rib cage assessment from biplanar radiographs could be a minimally invasive method of estimating pulmonary function before and after spinal fusion in patients with an AIS. The 3D RCV reflects virtual chest capacity and hence pulmonary function in this group of patients. Cite this article: Bone Joint J 2022;104-B(1):112–119


Bone & Joint Open
Vol. 3, Issue 12 | Pages 960 - 968
23 Dec 2022
Hardwick-Morris M Wigmore E Twiggs J Miles B Jones CW Yates PJ

Aims. Leg length discrepancy (LLD) is a common pre- and postoperative issue in total hip arthroplasty (THA) patients. The conventional technique for measuring LLD has historically been on a non-weightbearing anteroposterior pelvic radiograph; however, this does not capture many potential sources of LLD. The aim of this study was to determine if long-limb EOS radiology can provide a more reproducible and holistic measurement of LLD. Methods. In all, 93 patients who underwent a THA received a standardized preoperative EOS scan, anteroposterior (AP) radiograph, and clinical LLD assessment. Overall, 13 measurements were taken along both anatomical and functional axes and measured twice by an orthopaedic fellow and surgical planning engineer to calculate intraoperator reproducibility and correlations between measurements. Results. Strong correlations were observed for all EOS measurements (r. s. > 0.9). The strongest correlation with AP radiograph (inter-teardrop line) was observed for functional-ASIS-to-floor (functional) (r. s. = 0.57), much weaker than the correlations between EOS measurements. ASIS-to-ankle measurements exhibited a high correlation to other linear measurements and the highest ICC (r. s. = 0.97). Using anterior superior iliac spine (ASIS)-to-ankle, 33% of patients had an absolute LLD of greater than 10 mm, which was statistically different from the inter-teardrop LLD measurement (p < 0.005). Discussion. We found that the conventional measurement of LLD on AP pelvic radiograph does not correlate well with long leg measurements and may not provide a true appreciation of LLD. ASIS-to-ankle demonstrated improved detection of potential LLD than other EOS and radiograph measurements. Full length, functional imaging methods may become the new gold standard to measure LLD. Cite this article: Bone Jt Open 2022;3(12):960–968


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_10 | Pages 7 - 7
1 Jun 2023
Harris PC Lacey S Steward A Sertori M Homan J
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Introduction. The various problems that are managed with circular external fixation (e.g. deformity, complex fractures) also typically require serial plain x-ray imaging. One of the challenges here is that the relatively radio-opaque components of the circular external fixator (e.g. the rings) can obscure the view of the area of interest (e.g. osteotomy site, fracture site). In this presentation we describe how the geometry of the x-ray beam affects the produced image and how we can use knowledge of this to our advantage. Whilst this can be applied to any long bone, we have focused on the tibia, given that it's the most common long bone that is treated by circular external fixation. Materials & Methods. In the first part of the presentation we describe the known attributes (geometry) of the x-ray beam and postulate what effect it would have when we x-ray a long bone that is surrounded by a circular external fixator. In the second part we demonstrate this in practice using a tibia and a 3 ring circular external fixator. Differing x-ray beam orientations are used to demonstrate both how the geometry of the beam affects the produced image and how we can use this to our advantage to better visualise part of the bone. Results. The practical part of the study confirmed the theoretical part. Conclusions. Knowledge of the beam geometry can be used to minimise the obscuring nature of the circular fixator. This technique is simple and can be easily taught to the radiographer. It is a useful adjunct for the limb reconstruction surgeon


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_9 | Pages 26 - 26
1 Oct 2022
Bell J Owen D Meek K Terrill N Sanchez-Weatherby J Le Maitre C
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Background. An improved understanding of intervertebral disc (IVD) structure and function is required for treatment development. Loading induces micro-fractures at the interface between the nucleus pulposus (NP) and the annulus fibrosus (AF), which is hypothesized to induce a cascade of cellular changes leading to degeneration. However, there is limited understanding of the structural relationship between the NP and AF at this interface and particularly response to load. Here, X-ray scattering is utilised to provide hierarchical morphometric information of collagen structure across the IVD, especially the interface region under load. Methodology. IVDs were imaged using the I22 SAXS/WAXS beamline at Diamond Light Source. Peaks associated with the D-banded structure of collagen fibrils were fitted to quantify their azimuthal distribution, as well the magnitude and direction of internal strains under static and applied strain (0–20%). Results. IVD tissue regions exhibited structural “AF-like” and “NP-like” fingerprints. Demonstrating high internal strains on collagen fibres particularly within the NP region of the disc. AF and NP regions showed distinct collagen orientation and internal strains with an apparent lack of bracing structure seen at the interface between the differential mechanical tissues. X-ray scattering under tensile strain provided structural information at high resolution, with clear differences observed between normal and degenerate discs under load. Conclusion. X ray scattering has been utilised to develop an improved understanding of collagen structure across the intervertebral disc which can be utilised to gain an increased understanding of load induced propagation of micro fissures and disc degeneration. Conflict of Interest: No conflict of interest. Funding: BioPro Network, UCL for funding this study through support from the MRC (MR/R025673/1)


Bone & Joint Open
Vol. 3, Issue 6 | Pages 502 - 509
20 Jun 2022
James HK Griffin J Pattison GTR

Aims. To identify a core outcome set of postoperative radiographic measurements to assess technical skill in ankle fracture open reduction internal fixation (ORIF), and to validate these against Van der Vleuten’s criteria for effective assessment. Methods. An e-Delphi exercise was undertaken at a major trauma centre (n = 39) to identify relevant parameters. Feasibility was tested by two authors. Reliability and validity was tested using postoperative radiographs of ankle fracture operations performed by trainees enrolled in an educational trial (IRCTN 20431944). To determine construct validity, trainees were divided into novice (performed < ten cases at baseline) and intermediate groups (performed ≥ ten cases at baseline). To assess concurrent validity, the procedure-based assessment (PBA) was considered the gold standard. The inter-rater and intrarater reliability was tested using a randomly selected subset of 25 cases. Results. Overall, 235 ankle ORIFs were performed by 24 postgraduate year three to five trainees during ten months at nine NHS hospitals in England, UK. Overall, 42 PBAs were completed. The e-Delphi panel identified five ‘final product analysis’ parameters and defined acceptability thresholds: medial clear space (MCS); medial malleolar displacement (MMD); lateral malleolar displacement (LMD); tibiofibular clear space (TFCS) (all in mm); and talocrural angle (TCA) in degrees. Face validity, content validity, and feasibility were excellent. PBA global rating scale scores in this population showed excellent construct validity as continuous (p < 0.001) and categorical (p = 0.001) variables. Concurrent validity of all metrics was poor against PBA score. Intrarater reliability was substantial for all parameters (intraclass correlation coefficient (ICC) > 0.8), and inter-rater reliability was substantial for LMD, MMD, TCA, and moderate (ICC 0.61 to 0.80) for MCS and TFCS. Assessment was time efficient compared to PBA. Conclusion. Assessment of technical skill in ankle fracture surgery using the first postoperative radiograph satisfies the tested Van der Vleuten’s utility criteria for effective assessment. 'Final product analysis' assessment may be useful to assess skill transfer in the simulation-based research setting. Cite this article: Bone Jt Open 2022;3(6):502–509


Bone & Joint Research
Vol. 10, Issue 12 | Pages 830 - 839
15 Dec 2021
Robertson G Wallace R Simpson AHRW Dawson SP

Aims. Assessment of bone mineral density (BMD) with dual-energy X-ray absorptiometry (DXA) is a well-established clinical technique, but it is not available in the acute trauma setting. Thus, it cannot provide a preoperative estimation of BMD to help guide the technique of fracture fixation. Alternative methods that have been suggested for assessing BMD include: 1) cortical measures, such as cortical ratios and combined cortical scores; and 2) aluminium grading systems from preoperative digital radiographs. However, limited research has been performed in this area to validate the different methods. The aim of this study was to investigate the evaluation of BMD from digital radiographs by comparing various methods against DXA scanning. Methods. A total of 54 patients with distal radial fractures were included in the study. Each underwent posteroanterior (PA) and lateral radiographs of the injured wrist with an aluminium step wedge. Overall 27 patients underwent routine DXA scanning of the hip and lumbar spine, with 13 undergoing additional DXA scanning of the uninjured forearm. Analysis of radiographs was performed on ImageJ and Matlab with calculations of cortical measures, cortical indices, combined cortical scores, and aluminium equivalent grading. Results. Cortical measures showed varying correlations with the forearm DXA results (range: Pearson correlation coefficient (r) = 0.343 (p = 0.251) to r = 0.521 (p = 0.068)), with none showing statistically significant correlations. Aluminium equivalent grading showed statistically significant correlations with the forearm DXA of the corresponding region of interest (p < 0.017). Conclusion. Cortical measures, cortical indices, and combined cortical scores did not show a statistically significant correlation to forearm DXA measures. Aluminium-equivalent is an easily applicable method for estimation of BMD from digital radiographs in the preoperative setting. Cite this article: Bone Joint Res 2021;10(12):830–839


The Bone & Joint Journal
Vol. 103-B, Issue 11 | Pages 1662 - 1668
1 Nov 2021
Bhanushali A Chimutengwende-Gordon M Beck M Callary SA Costi K Howie DW Solomon LB

Aims. The aims of this study were to compare clinically relevant measurements of hip dysplasia on radiographs taken in the supine and standing position, and to compare Hip2Norm software and Picture Archiving and Communication System (PACS)-derived digital radiological measurements. Methods. Preoperative supine and standing radiographs of 36 consecutive patients (43 hips) who underwent periacetabular osteotomy surgery were retrospectively analyzed from a single-centre, two-surgeon cohort. Anterior coverage (AC), posterior coverage (PC), lateral centre-edge angle (LCEA), acetabular inclination (AI), sharp angle (SA), pelvic tilt (PT), retroversion index (RI), femoroepiphyseal acetabular roof (FEAR) index, femoroepiphyseal horizontal angle (FEHA), leg length discrepancy (LLD), and pelvic obliquity (PO) were analyzed using both Hip2Norm software and PACS-derived measurements where applicable. Results. Analysis of supine and standing radiographs resulted in significant variation for measurements of PT (p < 0.001) and AC (p = 0.005). The variation in PT correlated with the variation in AC in a limited number of patients (R. 2. = 0.378; p = 0.012). Conclusion. The significant variation in PT and AC between supine and standing radiographs suggests that it may benefit surgeons to have both radiographs when planning surgical correction of hip dysplasia. We also recommend using PACS-derived measurements of AI and SA due to the poor interobserver error on Hip2Norm. Cite this article: Bone Joint J 2021;103-B(11):1662–1668


The Bone & Joint Journal
Vol. 102-B, Issue 8 | Pages 1062 - 1071
1 Aug 2020
Cheung JPY Fong HK Cheung PWH

Aims. To determine the effectiveness of prone traction radiographs in predicting postoperative slip distance, slip angle, changes in disc height, and lordosis after surgery for degenerative spondylolisthesis of the lumbar spine. Methods. A total of 63 consecutive patients with a degenerative spondylolisthesis and preoperative prone traction radiographs obtained since 2010 were studied. Slip distance, slip angle, disc height, segmental lordosis, and global lordosis (L1 to S1) were measured on preoperative lateral standing radiographs, flexion-extension lateral radiographs, prone traction lateral radiographs, and postoperative lateral standing radiographs. Patients were divided into two groups: posterolateral fusion or posterolateral fusion with interbody fusion. Results. The mean changes in segmental lordosis and global lordosis were 7.1° (SD 6.7°) and 2.9° (SD 9.9°) respectively for the interbody fusion group, and 0.8° (SD 5.1°) and -0.4° (SD 10.1°) respectively for the posterolateral fusion-only group. Segmental lordosis (ρ = 0.794, p < 0.001) corrected by interbody fusion correlated best with prone traction radiographs. Global lumbar lordosis (ρ = 0.788, p < 0.001) correlated best with the interbody fusion group and preoperative lateral standing radiographs. The least difference in slip distance (-0.3 mm (SD 1.7 mm), p < 0.001), slip angle (0.9° (SD 5.2°), p < 0.001), and disc height (0.02 mm (SD 2.4 mm), p < 0.001) was seen between prone traction and postoperative radiographs. Regression analyses suggested that prone traction parameters best predicted correction of slip distance (Corrected Akaike’s Information Criterion (AICc) = 37.336) and disc height (AICc = 58.096), while correction of slip angle (AICc = 26.453) was best predicted by extension radiographs. Receiver operating characteristic (ROC) cut-off showed, with 68.3% sensitivity and 64.5% specificity, that to achieve a 3.0° increase in segmental lordotic angle, patients with a prone traction disc height of 8.5 mm needed an interbody fusion. Conclusion. Prone traction radiographs best predict the slip distance and disc height correction achieved by interbody fusion for lumbar degenerative spondylolisthesis. To achieve this maximum correction, interbody fusion should be undertaken if a disc height of more than 8.5 mm is attained on preoperative prone traction radiographs. Level of Evidence: Level II Prognostic Study. Cite this article: Bone Joint J 2020;102-B(8):1062–1071


The Bone & Joint Journal
Vol. 103-B, Issue 7 Supple B | Pages 59 - 65
1 Jul 2021
Bracey DN Hegde V Shimmin AJ Jennings JM Pierrepont JW Dennis DA

Aims. Cross-table lateral (CTL) radiographs are commonly used to measure acetabular component anteversion after total hip arthroplasty (THA). The CTL measurements may differ by > 10° from CT scan measurements but the reasons for this discrepancy are poorly understood. Anteversion measurements from CTL radiographs and CT scans are compared to identify spinopelvic parameters predictive of inaccuracy. Methods. THA patients (n = 47; 27 males, 20 females; mean age 62.9 years (SD 6.95)) with preoperative spinopelvic mobility, radiological analysis, and postoperative CT scans were retrospectively reviewed. Acetabular component anteversion was measured on postoperative CTL radiographs and CT scans using 3D reconstructions of the pelvis. Two cohorts were identified based on a CTL-CT error of ≥ 10° (n = 11) or < 10° (n = 36). Spinopelvic mobility parameters were compared using independent-samples t-tests. Correlation between error and mobility parameters were assessed with Pearson’s coefficient. Results. Patients with CTL error > 10° (10° to 14°) had stiffer lumbar spines with less mean lumbar flexion (38.9°(SD 11.6°) vs 47.4° (SD 13.1°); p = 0.030), different sagittal balance measured by pelvic incidence-lumbar lordosis mismatch (5.9° (SD 18.8°) vs -1.7° (SD 9.8°); p = 0.042), more pelvic extension when seated (pelvic tilt -9.7° (SD 14.1°) vs -2.2° (SD 13.2°); p = 0.050), and greater change in pelvic tilt between supine and seated positions (12.6° (SD 12.1°) vs 4.7° (SD 12.5°); p = 0.036). The CTL measurement error showed a positive correlation with increased CTL anteversion (r = 0.5; p = 0.001), standing lordosis (r = 0.23; p = 0.050), seated lordosis (r = 0.4; p = 0.009), and pelvic tilt change between supine and step-up positions (r = 0.34; p = 0.010). Conclusion. Differences in spinopelvic mobility may explain the variability of acetabular anteversion measurements made on CTL radiographs. Patients with stiff spines and increased compensatory pelvic movement have less accurate measurements on CTL radiographs. Flexion of the contralateral hip is required to obtain clear CTL radiographs. In patients with lumbar stiffness, this movement may extend the pelvis and increase anteversion of the acetabulum on CTL views. Reliable analysis of acetabular component anteversion in this patient population may require advanced imaging with a CT scan. Cite this article: Bone Joint J 2021;103-B(7 Supple B):59–65


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_13 | Pages 43 - 43
7 Aug 2023
Lewis A Bucknall K Davies A Evans A Jones L Triscott J Hutchison A
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Abstract. Introduction. A lipohaemarthrosis seen on Horizontal beam lateral X-ray in acute knee injury is often considered predictive of an intra-articular fracture requiring further urgent imaging. Methodology. We retrospectively searched a five-year X-ray database for the term “lipohaemarthrosis”. We excluded cases if the report concluded “no lipohaemarthrosis” or “lipohaemarthrosis” AND “fracture”. All remaining cases were reviewed by an Orthopaedic Consultant with a special interest in knee injuries (AD) blinded to the report. X-rays were excluded if a fracture was seen, established osteoarthritic change was present, a pre-existing arthroplasty present or no lipohaemarthrosis present. Remaining cases were then studied for any subsequent Radiological or Orthopaedic surgical procedures. Results. 136 cases were identified and reviewed by an Orthopaedic Consultant. 31 were excluded for no lipohaemarthrosis (n= 11), for degenerative change (n=9), for fracture (n=4), for existing arthroplasty (n=4) and for data errors (n=3). The remaining 105 patients had a mean age of 32, and range 5–90 years. 66 patients underwent further imaging in the form of MRI scan (n=47), CT Scan (n=9) repeat x-rays (n=9) and ultrasound (n=1). 27 fractures were identified. Surgery was performed in 12 cases (11%). Two (2%) urgently (One ACL reconstruction plus meniscus repair, one for ORIF of tibial plateau fracture). Ten (10%) had elective surgery (6 for ACL reconstruction, 2 for ACL reconstruction plus meniscus repair, 2 for loose body removal. Conclusion. The presence of a lipohaemarthrosis on x-ray following acute knee injury was a poor predictor of intra-articular fracture (26%) or need for urgent surgery (2%)


Bone & Joint Research
Vol. 10, Issue 3 | Pages 173 - 187
1 Mar 2021
Khury F Fuchs M Awan Malik H Leiprecht J Reichel H Faschingbauer M

Aims. To explore the clinical relevance of joint space width (JSW) narrowing on standardized-flexion (SF) radiographs in the assessment of cartilage degeneration in specific subregions seen on MRI sequences in knee osteoarthritis (OA) with neutral, valgus, and varus alignments, and potential planning of partial knee arthroplasty. Methods. We retrospectively reviewed 639 subjects, aged 45 to 79 years, in the Osteoarthritis Initiative (OAI) study, who had symptomatic knees with Kellgren and Lawrence grade 2 to 4. Knees were categorized as neutral, valgus, and varus knees by measuring hip-knee-angles on hip-knee-ankle radiographs. Femorotibial JSW was measured on posteroanterior SF radiographs using a special software. The femorotibial compartment was divided into 16 subregions, and MR-tomographic measurements of cartilage volume, thickness, and subchondral bone area were documented. Linear regression with adjustment for age, sex, body mass index, and Kellgren and Lawrence grade was used. Results. We studied 345 neutral, 87 valgus, and 207 varus knees. Radiological JSW narrowing was significantly (p < 0.01) associated with cartilage volume and thickness in medial femorotibial compartment in neutral (r = 0.78, odds ratio (OR) 2.33) and varus knees (r = 0.86, OR 1.92), and in lateral tibial subregions in valgus knees (r = 0.87, OR 3.71). A significant negative correlation was found between JSW narrowing and area of subchondral bone in external lateral tibial subregion in valgus knees (r = −0.65, p < 0.01) and in external medial tibial subregion in varus knees (r = −0.77, p < 0.01). No statistically significant correlation was found in anterior and posterior subregions. Conclusion. SF radiographs can be potentially used for initial detection of cartilage degeneration as assessed by MRI in medial and lateral but not in anterior or posterior subregions. Cite this article: Bone Joint Res 2021;10(3):173–187


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_16 | Pages 30 - 30
17 Nov 2023
Swain L Holt C Williams D
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Abstract. Objectives. Investigate Magnetic Resonance Imaging (MRI) as an alternative to Computerised Tomography (CT) when calculating kinematics using Biplane Video X-ray (BVX) by quantifying the accuracy of a combined MRI-BVX methodology by comparing with results from a gold-standard bead-based method. Methods. Written informed consent was given by one participant who had four tantalum beads implanted into their distal femur and proximal tibia from a previous study. Three-dimensional (3D) models of the femur and tibia were segmented (Simpleware Scan IP, Synopsis) from an MRI scan (Magnetom 3T Prisma, Siemens). Anatomical Coordinate Systems (ACS) were applied to the bone models using automated algorithms. 1. The beads were segmented from a previous CT and co-registered with the MRI bone models to calculate their positions. BVX (60 FPS, 1.25 ms pulse width) was recorded whilst the participant performed a lunge. The beads were tracked, and the ACS position of the femur and tibia were calculated at each frame (DSX Suite, C-Motion Inc.). The beads were digitally removed from the X-rays (MATLAB, MathWorks) allowing for blinded image-registration of the MRI models to the radiographs. The mean difference and standard deviation (STD) between bead-generated and image-registered bone poses were calculated for all degrees of freedom (DOF) for both bones. Using the principles defined by Grood and Suntay. 2. , 6 DOF kinematics of the tibiofemoral joint were calculated (MATLAB, MathWorks). The mean difference and STD between these two sets of kinematics were calculated. Results. The absolute mean femur and tibia ACS position differences (Table 1) between the bead and image-registered poses were found to be within 0.75mm for XYZ, with all STD within ±0.5mm. Mean rotation differences for both bones were found to be within 0.2º for XYZ (Table 1). The absolute mean tibiofemoral joint translations (Table 1) were found to be within ±0.7mm for all DOF, with the smallest absolute mean in compression-distraction. The absolute mean tibiofemoral rotations were found to be within 0.25º for all DOF (Table 1), with the smallest mean was found in abduction-adduction. The largest mean and STD were found in internal-external rotation due to the angle of the X-rays relative to the joint movement, increasing the difficulty of manual image registration in that plane. Conclusion. The combined MRI-BVX method produced bone pose and tibiofemoral kinematics accuracy similar to previous CT results. 3. This allows for confidence in future results, especially in clinical applications where high accuracy is needed to understand the effects of disease and the efficacy of surgical interventions. Acknowledgements: This research was supported by the Engineering and Physical Sciences Research Council (EPSRC) doctoral training grant (EP/T517951/1). Declaration of Interest. (b) declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research reported:I declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research project


The Bone & Joint Journal
Vol. 102-B, Issue 7 Supple B | Pages 41 - 46
1 Jul 2020
Ransone M Fehring K Fehring T

Aims. Patients with abnormal spinopelvic mobility are at increased risk for instability. Measuring the change in sacral slope (ΔSS) can help determine spinopelvic mobility preoperatively. Sacral slope (SS) should decrease at least 10° to demonstrate adequate posterior pelvic tilt. There is potential for different ΔSS measurements in the same patient based on sitting posture. The purpose of this study was to determine the effect of sitting posture on the ΔSS in patients undergoing total hip arthroplasty (THA). Methods. In total, 51 patients undergoing THA were reviewed to quantify the variability in preoperative spinopelvic mobility when measuring two different sitting positions using SS for planning. Results. A total of 32 patients had standardized relaxed sitting radiographs, while 35 patients had standardized flexed sitting images. Of the 32 patients with relaxed sitting views, the mean ΔSS was 20.7° (SD 8.9°). No patients exhibited an increase in SS during relaxed sitting (i.e. anterior pelvic tilt or so-called reverse accommodation). Of the 35 patients with flexed sitting radiographs, the mean ΔSS was only 2.1° (SD 9.7°) with 16/35 (45.71%) showing anterior pelvic tilt, or so-called reverse accommodation, unexpectedly increasing the sitting SS compared to the standing SS. Overall, 18 patients had both relaxed sitting and flexed sitting radiographs. In patients with both types of sitting radiographs, the mean relaxed sit to stand ΔSS was 18.06° (SD 6.07°), while only a 3.00° (SD 10.53°) ΔSS was noted when flexed sitting. There was a mean ΔSS difference of 15.06° (SD 7.67°) noted in the same patient cohort depending on sitting posture (p < 0.001). Conclusion. A 15° mean difference was noted depending on the sitting posture of the patient. Since decisions on component position can be made on preoperative lateral sit-stand radiographs, postural standardization is crucial. If using ΔSS for preoperative planning, the relaxed sitting radiograph is preferred. Cite this article: Bone Joint J 2020;102-B(7 Supple B):41–46


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_1 | Pages 94 - 94
1 Feb 2020
Hagio K Akiyama K Aikawa K Saito M
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Introduction. In our institution, we started to perform THA with SuperPATH approach, including preservation of soft tissue around the hip (James Chow et al. Musculoskelet Med 2011) since July 2014, aiming for fast recovery and prevention of hip dislocation. For minimally-invasive approaches, however, there have been a few reports on malalignment of the implants related to shortage of operative field. The purpose of this study is to examine the short-term results of THA using SuperPATH, especially implant alignment. Materials and methods. We performed a study of 45 patients (45 hips) with osteoarthritis of the hip joint who had a THA with SuperPATH approach. There were 8 men and 37 women with an average age of 73 years, which were minimally 24 months followed. Dynasty Bioform cup and Profemur Z stem (Microport Orthopaedics) were used for all cases. Patients were clinically assessed with Merle d'Aubigne score and complications. Implant alignment and stability were radiologically evaluated by annual X-ray and CT acquired two months after surgery. Results. Merle d'Aubigne score was 10.2 (pain:2.8, mobility:4.4 walking ability:3.0) preoperatively and 16.6(pain:5.8, mobility:5.8, walking ability:5.0) at the latest follow-up. There were no dislocation and infection, but intraoperative proximal femoral fracture was found for two cases, which was managed to treat with additional circulating wire intraoperatively. Latest follow-up X-ray image showed 95% of the stem A-P alignment to be within 2 degrees and 5% to be more than 2 degrees and less than 5 degrees, while 44% of the stem lateral alignment to be within 2 degrees, 47% to be more than 2 degrees and less than 5 degrees, and 8% to be more than 5 degrees. From CT images averaged cup position found to be 40±5 degrees for inclination, and 19±5 degrees for anatomic anteversion, averaged stem anteversion to be 33±9 degrees. Annual X-ray evaluation showed no radiolucent line and less than Grade 2 stress-shielding (Engh classification) around the implants for all cases. One case had more than 5mm subsidence of the stem in early postoperative period, but not progressively subsided. No loosening of components was evident. Discussion and Conclusion. Many minimally-invasive approaches have developed, there have been many reports on fast recovery and low incidence of postoperative hip dislocation, however, the risk of complications or malalignment related to shortage of operative field has been pointed out. In this study, intraoperative proximal femoral fracture occurred for two cases. Also, though there were no loosening and the components position seemed excellent but lateral view of the X-ray showed 8% to be more than 5 degrees tilting alignment, resulting from femoral broaching required before femoral neck resection. SuperPATH approach, including pass way from between the Gluteus Medius and the piriformis tendon, can preserve the whole short external rotators and capsule of the hip joint, leading to fast recovery and low incidence of postoperative dislocation. Moreover, this approach may be friendly to the surgeons familiar with the posterior approach because of easily conversion to the conventional posterior approach


Bone & Joint Open
Vol. 1, Issue 9 | Pages 594 - 604
24 Sep 2020
James HK Pattison GTR Griffin J Fisher JD Griffin DR

Aims. To develop a core outcome set of measurements from postoperative radiographs that can be used to assess technical skill in performing dynamic hip screw (DHS) and hemiarthroplasty, and to validate these against Van der Vleuten’s criteria for effective assessment. Methods. A Delphi exercise was undertaken at a regional major trauma centre to identify candidate measurement items. The feasibility of taking these measurements was tested by two of the authors (HKJ, GTRP). Validity and reliability were examined using the radiographs of operations performed by orthopaedic resident participants (n = 28) of a multicentre randomized controlled educational trial (ISRCTN20431944). Trainees were divided into novice and intermediate groups, defined as having performed < ten or ≥ ten cases each for DHS and hemiarthroplasty at baseline. The procedure-based assessment (PBA) global rating score was assumed as the gold standard assessment for the purposes of concurrent validity. Intra- and inter-rater reliability testing were performed on a random subset of 25 cases. Results. In total, 327 DHS and 248 hemiarthroplasty procedures were performed by 28 postgraduate year (PGY) 3 to 5 orthopaedic trainees during the 2014 to 2015 surgical training year at nine NHS hospitals in the West Midlands, UK. Overall, 109 PBAs were completed for DHS and 80 for hemiarthroplasty. Expert consensus identified four ‘final product analysis’ (FPA) radiological parameters of technical success for DHS: tip-apex distance (TAD); lag screw position in the femoral head; flushness of the plate against the lateral femoral cortex; and eight-cortex hold of the plate screws. Three parameters were identified for hemiarthroplasty: leg length discrepancy; femoral stem alignment; and femoral offset. Face validity, content validity, and feasibility were excellent. For all measurements, performance was better in the intermediate compared with the novice group, and this was statistically significant for TAD (p < 0.001) and femoral stem alignment (p = 0.023). Concurrent validity was poor when measured against global PBA score. This may be explained by the fact that they are measuring difference facets of competence. Intra-and inter-rater reliability were excellent for TAD, moderate for lag screw position (DHS), and moderate for leg length discrepancy (hemiarthroplasty). Use of a large multicentre dataset suggests good generalizability of the results to other settings. Assessment using FPA was time- and cost-effective compared with PBA. Conclusion. Final product analysis using post-implantation radiographs to measure technical skill in hip fracture surgery is feasible, valid, reliable, and cost-effective. It can complement traditional workplace-based assessment for measuring performance in the real-world operating room . It may have particular utility in competency-based training frameworks and for assessing skill transfer from the simulated to live operating theatre. Cite this article: Bone Joint Open 2020;1-9:594–604


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_7 | Pages 27 - 27
1 Jul 2020
Hurry J Spurway A Dunbar MJ El-Hawary R
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Radiostereometric analysis (RSA) allows for precise measurement of interbody distances on X-ray images, such as movement between a joint replacement implant and the bone. The low radiation biplanar EOS imager (EOS imaging, France) scans patients in a weight-bearing position, provides calibrated three-dimensional information on bony anatomy, and could limit the radiation during serial RSA studies. Following the ISO-16087 standard, 15 double exams were conducted to determine the RSA precision of total knee arthroplasty (TKA) patients in the EOS imager, compared to the standard instantaneous, cone-beam, uniplanar digital X-ray set-up. At a mean of 5 years post-surgery, 15 TKA participants (mean 67 years, 12 female, 3 male) were imaged twice in the biplanar imager. To reduce motion during the scan, a support for the foot was added and the scan speed was increased. The voltage was also increased compared to standard settings for better marker visibility over the implant. A small calibration object was included to remove any remaining sway in post-processing. The 95% confidence interval precision was 0.11, 0.04, and 0.15 mm in the x, y, and z planes, respectively and 0.15, 0.20, and 0.14° in Rx, Ry, and Rz. Two participants had motion artifacts successfully removed during post-processing using the small calibration object. With faster speeds and stabilization support, this study found an in vivo RSA precision of ≤ 0.15 mm and ≤ 0.20° for TKA exams, which is within published uniplanar values for arthroplasty RSA. The biplanar imager also adds the benefits of weight bearing imaging, 3D alignment measurements, a lower radiation dose, and does not require a reference object due to known system geometry and automatic image registration


Bone & Joint Research
Vol. 5, Issue 9 | Pages 436 - 441
1 Sep 2016
Pinsornsak P Naratrikun K Kanitnate S Sangkomkamhang T

Objectives. The purpose of this study was to compare the joint space width between one-leg and both-legs standing radiographs in order to diagnose a primary osteoarthritis of the knee. Methods. Digital radiographs of 100 medial osteoarthritic knees in 50 patients were performed. The patients had undergone one-leg standing anteroposterior (AP) views by standing on the affected leg while a both-legs standing AP view was undertaken while standing on both legs. The severity of the osteoarthritis was evaluated using the joint space width and Kellgren-Lawrence (KL) radiographic classification. The t-test was used for statistical analysis. Results. The mean medial joint space width found in the one-leg and in the both-legs standing view were measured at 1.8 mm and 2.4 mm, respectively (p < 0.001, 95% CI 0.5 to 0.7). 33%, 47.4% and 23.1% of the knees diagnosed with a KL grade of I, II and III in the both-legs standing views were changed to KL grade II, III and IV in the one-leg standing views, respectively. No changes for KL IV osteoarthritis diagnoses have been found between both- and one-leg standing views. Conclusions. One-leg standing radiographs better represent joint space width than both-legs standing radiographs. 32% of both-legs standing radiographs have changed the KL grading to a more severe grade than that in the one-leg standing radiographs. Cite this article: P. Pinsornsak, K. Naratrikun, S. Kanitnate, T. Sangkomkamhang. The one-leg standing radiograph: An improved technique to evaluate the severity of knee osteoarthritis. Bone Joint Res 2016;5:436–441. DOI: 10.1302/2046-3758.59.BJR-2016-0049.R1


Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_13 | Pages 5 - 5
17 Jun 2024
Aamir J Caldwell R Karthikappallil D Tanaka H Elbannan M Mason L
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Background. Lisfranc fracture dislocations are uncommon injuries, which frequently require surgical intervention. Currently, there is varying evidence on the diagnostic utility of plain radiographs (XR) and CT in identifying Lisfranc injuries and concomitant fractures. Our aim was to identify the utility of XR as compared to CT, with the nul hypothesis that there was no difference in fracture identification. Methods. A retrospective assessment of patients who had sustained a Lisfranc injury between 2013 and 2022 across two trauma centres within the United Kingdom who underwent surgery. Pre-operative XR and CT images were reviewed independently by 2 reviewers to identify the presence of associated fractures. Results. A total of 175 patients were included. Our assessment identified that XR images significantly under-diagnosed all metatarsal and midfoot fractures. The largest discrepancies between XR and CT in their rates of detection were in fractures of the cuboid (5.7% vs 28%, p<0.001), medial cuneiform (20% vs 51%, p=0.008), lateral cuneiform (4% vs 36%, p=0.113), second metatarsal (57% vs 82%, p<0.001), third metatarsal (37% vs 61%, p<0.001) and fourth metatarsal (26% vs 43%, p<0.001). As compared to CT, the sensitivity of XR was low. The lowest sensitivity for identification however was lateral foot injuries, specifically fractures of the lateral cuneiform (sensitivity 7.94%, specificity 97.3%), cuboid (sensitivity 18.37%, specificity 99.21%), fourth (sensitivity 46.7%, specificity 89.80%) and fifth metatarsal (sensitivity 45.00%, specificity 96.10%). Conclusion. From our analysis, we can determine that XR significantly under-diagnoses associated injuries in patient sustaining an unstable Lisfranc injury, with lateral foot injuries being the worst identified. We advised the use of CT imaging in all cases for appropriate surgical planning


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_5 | Pages 2 - 2
1 Apr 2018
Jo S Lee S Kang S
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Introduction. The correct anteversion of the acetabular cup is critical to achieve optimal outcome after total hip arthroplasty. While number of method has been described to measure the anteversion in plane anteroposterior and lateral radiograph, it is still controversial which method provides best anteversion measurement. While many of the previous studies used CT scan to validate the anteversion measured in plane anteroposterior radiograph, this may cause potential bias as the anteversion measured in CT scan reflects true anteversion while the anteversion measurement methods in plane radiograph are design to measure the planar anteversion. Thus, in the current study, we tried to find the optimal anteversion measurement method free from the previously described bias. Material and method. Custom made cup model was developed which enables change in anteversion and inclination. Simple radiograph was taken with the cup in 10° to 70° degree of inclination at 10° increments and for each inclination angle, anteversion was corrected from 0° to 30° at 5° increments. The radiograph was taken with the beam directed at the center of the cup (mimicking hip centered anteroposterior radiograph) and at 9cm medial to the cup (mimicking pelvis anteroposterior radiograph). The measurements were done by two orthopaedic surgeons using methods described by 1) Pradhan et al, 2) Lewinak et al, 3) Widmer et al, and 4) Liaw et al. For each measurements, the anteversion were compared with the actual anteversion. Result. Interoverver correlation (kappa value) were high in all measurements ranging 0.988 to 0.998. Regardless of how the radiograph was taken, Pradhan method was the most accurate measurement method showing difference of 2.17° ± 1.69° and −2.5° ± 1.93° compare to the actual anteversion respectively for hip centered radiograph and pelvis anteroposterior radiograph. The Widmer method showed the least accuracy (pelvis AP : −6.75° ± 4.62°, hip centered AP : −14.84° ± 4.36°). However, when the anteversion were measured in the safe zone with the inclination in 30° to 50° Liaw's method in hip centered radiograph showed the highest accuracy (1.63° ± 1.4°). Conclusion. The study indicates that the Pradhan's method may provide the most accurate anteversion measurement. However, with the hip in 30° to 50° inclination, Liaw's method measured from hip centred radiograph will provide most accurate anteversion measurement


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_12 | Pages 7 - 7
1 Oct 2019
Ransone M Fehring K Fehring TK
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Introduction. Patients with abnormal spinopelvic mobility are at increased risk for hip instability. Measuring the change in sacral slope (ΔSS) with standing and seated lateral radiographs is commonly used to determine spinopelvic mobility pre-operatively. Sacral slope should decrease at least 10 degrees to demonstrate adequate accommodation. Accommodation of <10 deg necessitates acetabular component position change or use of a dual mobility implant. There is potential for different ΔSS measurements in the same patient based on sitting posture. Methods. 78 patients who underwent THA were reviewed to quantify the variability in pre-operative spinopelvic mobility when two different seated positions (relaxed sitting v. pre-rise sitting) were used in the same patient. Results. 34 patients had standardized pre-rise sitting x-rays, while 44 patients had standardized relaxed sitting x-rays. Of the 44 patients with relaxed sitting x-rays, the mean ΔSS (ΔrSS) was 20.4 degrees. No patients exhibited an increase in sacral slope when sitting (ie; reverse accommodation). Of the 34 patients with pre-rise sitting x-rays, the mean pre-rise sit-stand change (ΔprSS) was only 1.85 degrees with 47% (16/34) showing reverse accommodation, actually increasing the seated sacral slope compared to standing sacral slope. 18 patients had both pre-rise and relaxed sitting x-rays. In patients with both seated x-rays, the mean relaxed sit-stand change in sacral slope (ΔrSS) was 18.1 ± 6.1 degrees and only 3.0 ± 10.5 degrees for pre-rise sit-stand (ΔprSS), with a mean ΔSS difference of the 15.1 degrees (p <0.0001). Conclusion. A 15 degrees error could be made in pre-operative planning depending on the seated posture of the patient. Since decisions on component position or use of dual-mobility are made on pre-operative lateral sit-stand radiographs, postural standardization is critical. The relaxed seated radiograph is the preferred posture at the time of the seated lateral radiograph. For any tables or figures, please contact the authors directly


The Bone & Joint Journal
Vol. 95-B, Issue 8 | Pages 1114 - 1120
1 Aug 2013
Wijdicks CA Anavian J Hill BW Armitage BM Vang S Cole PA

The glenopolar angle assesses the rotational alignment of the glenoid and may provide prognostic information and aid the management of scapula fractures. We have analysed the effect of the anteroposterior (AP) shoulder radiograph rotational offset on the glenopolar angle in a laboratory setting and used this to assess the accuracy of shoulder imaging employed in routine clinical practice. Fluoroscopic imaging was performed on 25 non-paired scapulae tagged with 2 mm steel spheres to determine the orientation of true AP views. The glenopolar angle was measured on all the bony specimens rotated at 10° increments. The mean glenopolar angle measured on the bone specimens in rotations between 0° and 20° and thereafter was found to be significantly different (p < 0.001). We also obtained the AP radiographs of the uninjured shoulder of 30 patients treated for fractures at our centre and found that none fitted the criteria of a true AP shoulder radiograph. The mean angular offset from the true AP view was 38° (10° to 65°) for this cohort. Radiological AP shoulder views may not fully project the normal anatomy of the scapular body and the measured glenopolar angle. The absence of a true AP view may compromise the clinical management of a scapular fracture. Cite this article: Bone Joint J 2013;95-B:1114–20


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_3 | Pages 32 - 32
1 Feb 2017
Barnes L
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Introduction. When performing a total hip arthroplasty (THA), some surgeons routinely perform an intraoperative anteroposterior (AP) pelvis radiograph to assess components. The purpose of this study was to evaluate the reliability of the intraoperative radiograph to accurately reflect acetabular inclination, leg length, and femoral offset as compared to the immediate postoperative supine AP radiograph. Methods. The intraoperative (lateral decubitus position) and immediate postoperative (supine position) AP pelvis x-rays of 100 consecutive patients undergoing primary THA were retrospectively reviewed. Acetabular inclination, leg length, and femoral offset were measured on both radiographs. We analyzed the correlation coefficient of the recorded measurements between the two films as well as the interobserver reliability of each measurement obtained. Results. Our data demonstrated a high positive correlation between the intraoperative and postoperative acetabular inclination measurements of both reviewers (r=.886 and .896). In addition, no significant difference was observed between the inclination measurements (p= .06 and .37). There was a moderate correlation among the leg length (r= .58 and .66) and poor correlation among the offset (r= .29 and .25) between the two radiographs. One observer generated a significant difference between leg length measurements while both reviewers generated a significant difference between offset measurements. Interobserver reliability was high for all measurements. Conclusion. Intraoperative AP radiographs are commonly obtained during THA to aid in evaluation of component position and size, femoral neck cut, femoral canal fill, and detection of occult fractures. Results from this study suggest that this film could also be used to accurately measure acetabular inclination, but is a less reliable indicator of femoral offset and leg length when compared to the immediate postoperative film. In addition, the high interobserver correlation illustrates the high reproducibility of the measurement methods utilized


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_4 | Pages 33 - 33
1 Apr 2019
Kato M Warashina H
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Purpose. Leg length discrepancy after total hip arthroplasty (THA) sometimes causes significant patient dissatisfaction. In consideration of the leg length after THA, leg length discrepancy is often measured using anteroposterior (AP) pelvic radiography. However, some cases have discrepancies in femoral and tibial lengths, and we believe that in some cases, true leg length differences should be taken into consideration in total leg length measurement. We report the lengths of the lower limb, femur, and tibia measured using the preoperative standing AP full-leg radiographs of the patients who underwent THA. Materials and methods. From August 2013 to February 2017, 282 patients underwent standing AP full-leg radiography before THA. Of the patients, 33 were male and 249 were female. The mean age of the patients was 65.7±9.4 years. We measured the distances between the center of the tibial plafond and lesser trochanter apex (A-L), between the femoral intercondylar notch and lesser trochanter (K-L), and between the centers of the tibial plafond and intercondylar spine of the tibia (A-K) on standing AP full-leg radiographs before THA operation. We examined the differences in leg length and the causes of these discrepancies after guiding the difference between them. Results. The mean A-L was 674±44 mm on the right and 677±43 mm on the left. The mean difference between the left and the right was 6.2±7 mm. The differences of ≥5 and ≥10 mm between the left and right were confirmed in 131 (46%) and 39 cases (14%), respectively. The mean K-L was 343±23 mm on the right and 343±23 mm on the left, with a mean difference of 4.4±4 mm. The lateral differences of ≥5 and ≥10 mm were confirmed in 88 (31%) and 22 (8%), respectively. The mean A-K was 325±22 mm on the right and 327±22 mm on the left, with a mean difference of 4±4.5 mm. The differences of ≥5 and ≥10 mm between the left and right were confirmed in 24 (9%) and 67 cases (%), respectively. Discussion. Considering the total length of the lower limbs beyond the little trochanter and the leg length after THA, we confirmed that 46% of the leg length differences of ≥5 mm were admitted to 14%. Thus, THA appeared effective. Perthes head, Crowe classifications 3 and 4, history of childhood paralysis, and so on may be factors for leg length differences beyond the lesser trochanter. Conclusion. We think that it would be preferable to prepare a preoperative plan to measure leg length after THA by measuring the total length of the lower extremity before surgery and determining the difference between the left and right sides


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_14 | Pages 103 - 103
1 Nov 2018
Mulliez M Grupp T
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Crosslinking has been already used for about 80 years to enhance the longevity of polyethylene cables. The polymer alteration has been achieved with peroxide, silane or irradiation. The medical devices industry discovered the benefit of this technology for its tribological applications like hip or knee bearings in the 2000s as crosslinking improves considerably the abrasion resistance of the material. The more current methods used are Gamma and Beta irradiation. On the basis of economical (rising prices of Cobalt), environmental (the radioactive source can not be turned off), technological (low dose rate) drawbacks for Gamma respectively low penetration for Beta irradiation we decided to investigate an alternative technology: the X-Ray irradiation, which provides a homogeneous crosslinking in a relatively short time. We analyzed the wear, mechanical, thermal, oxidative and network properties of two vitamin E doped UHMWPE: first crosslinked with E-Beam, second with X-Ray. There wasn't any significant difference between the X-Ray and the E-Beam crosslinked material


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_2 | Pages 17 - 17
1 Jan 2019
Jalal M Simpson H Wallace R
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Appropriate in vivo models can be used to understand atrophic non-union pathophysiology. In these models, X-ray assessment is essential and a reliable good quality images are vital in order to detect any hidden callus formation or deficiency. However, the radiographic results are often variable and highly dependent on rotation and positioning from the detector/film. Therefore, standardised A-P and lateral x-ray views are essential for providing a full radiological picture and for reliably assessing the degree of fracture union. We established and evaluated a method for standardised imaging of the lower limb and for reliably obtaining two perpendicular views (e.g. true A-P and true lateral views). The normal position of fibula in murine models is posterolateral to the tibia, therefore, a proper technique must show fibula in both views. In order to obtain the correct position, the knee joint and ankle joints were flexed to 90 degrees and the foot was placed in a perpendicular direction with the x-ray film. To achieve this, a leg holder was made and used to hold the foot and the knee while the body was in the supine position. Lateral views were obtained by putting the foot parallel to the x-ray film. Adult Wister rat cadavers were used and serial x-rays were taken. A-P view in supine position showed the upper part of the fibula clearly, however, there was an unavoidable degree of external rotation in the whole lower limb, and the lower part of the fibula appeared behind the tibia. Therefore, a true A-P view whilst the body was in the supine position was difficult. To overcome this, a P-A view of the leg was performed with the body prone position, this allowed both upper and lower parts of the fibula to appear clearly in both views. This method provides two true perpendicular views (P-A and lateral) and helped to optimise radiological assessment


Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_2 | Pages 6 - 6
2 Jan 2024
Orellana F Grassi A Wahl P Nuss K Neels A Zaffagnini S Parrilli A
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A comprehensive understanding of the self-repair abilities of menisci and their overall function in the knee joint requires three-dimensional information. However, previous investigations of the meniscal blood supply have been limited to two-dimensional imaging methods, which fail to accurately capture tissue complexity. In this study, micro-CT was used to analyse the 3D microvascular structure of the meniscus, providing a detailed visualization and precise quantification of the vascular network.

A contrast agent (μAngiofil®) was injected directly into the femoral artery of cadaver legs to provide the proper contrast enhancement. First, the entire knee joint was analysed with micro-CT, then to increase the applicable resolution the lateral and medial menisci were excised and investigated with a maximum resolution of up to 4 μm. The resulting micro-CT datasets were analysed both qualitatively and quantitatively. Key parameters of the vascular network, such as vascular volume fraction, vessel radius, vessel length density, and tortuosity, were separately determined for the lateral and medial meniscus, and their four circumferential zones defined by Cooper.

In accordance with previous literature, the quantitative micro-CT data confirm a decrease in vascular volume fraction along the meniscal zones. The highest concentration of blood vessels was measured in the meniscocapsular region 0, which is characterized by vascular segments with a significantly larger average radius. Furthermore, the highest vessel length density observed in zone 0 suggests a more rapid delivery of oxygen and nutrients compared to other regions. Vascular tortuosity was detected in all circumferential regions, indicating the occurrence of vascular remodelling in all tissue areas.

In conclusion, micro-CT is a non-invasive imaging technique that allows for the visualization of the internal structure of an object in three dimensions. These advanced 3D vascular analyses have the potential to establish new surgical approaches that rely on the healing potential of specific areas of the meniscus.

Acknowledgements: The authors acknowledge R. Hlushchuk, S. Halm, and O. Khoma from the University of Bern for their help with contrast agent perfusions.


The Bone & Joint Journal
Vol. 99-B, Issue 5 | Pages 697 - 701
1 May 2017
Massa BSF Guarniero R Godoy Jr RM Rodrigues JC Montenegro NB Cordeiro FG

Aims. This pilot study aimed to evaluate prospectively the use of inlet radiographs of the hip as an alternative method of the assessment of reduction after the surgical treatment of developmental dysplasia of the hip (DDH). Patients and Methods. The children in this study underwent surgery between January 2013 and January 2015. All had inlet radiographs and CT scans post-operatively. Data were analysed by determining inter-observer reliability and intra-observer reproducibility, using the kappa value (K). Differences were settled by discussion between the two observers until a consensus was reached. The sensitivity and specificity of the radiographic and CT results were compared. A total of 26 radiographs were obtained from 23 children, with a mean age of 2.38 years (one to five). Results. Similar high levels of intra- and inter-observer agreement were observed (K = 0.834, 95% confidence interval (CI)). There was a high agreement between the radiographic and CT results (K = 0.834, 5% CI), with excellent sensitivity and a specificity of 95.5%. Conclusion. These results suggest that inlet radiographs may be a reliable method of assessing the reduction of the hip after the surgical treatment of DDH. Cite this article: Bone Joint J 2017;99-B:697–701


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_34 | Pages 571 - 571
1 Dec 2013
Vangeneugden D Van Den Broeck J Chellaoui K Schotanus M Boonen B Kort N
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Background. The full leg x-ray is a widely used imaging modality for post-operative assessment of total knee replacement (TKR). However, these assessments require controlled conditions and precise measuring in order to be accurate. inter-observer reliability remains a matter of concern as well. This study examines whether intersurgeon differences are significant. Method. Post-operative lateral and full-leg frontal x-rays of 26 patients were assessed by 6 surgeons according to a strict measuring protocol. Four measurements (Figure 1 and 2) were taken of which two were on the femur (Femoral Varus Angle FVA and Femoral Flexion Angle FFA) and two, on the tibia (Tibial Varus Angle TVA; Tibial Slope Angle TSA). A random effects, two-way ANOVA was performed on the data using Minitab (v 16.0, Minitab Inc., Pennsylvania, USA) to determine whether a surgeon has influence on the results (α = 0.05). Intra-class correlation coefficients (ICC) and standard error of measurements (SEM) resulting in smallest detectable changes (SDC) were also calculated [1]. Results. The resulting p-value for FVA is p = 0.246, p = 0.006 for FFA, p = 0.006 for TVA and p = 0.032 for TSA. The measured ICC of FVA is 0.88, 0.75 of FFA, 0.76 of TVA and 0.76 of TSA. Additionally, the SEM and SDC for FVA are respectively 0.26° and 0.72°, 0.84° and 2.36° for FFA, 0.45° and 1.26° for TVA and 0.66° and 0.86° for TSA. Discussion. The ANOVA shows for FFA, TVA and TSA a significant influence of the surgeon on the measurement result. Difficulty in indicating the implant line and the sensitivity of short lines to angular measurement could be reasons for the significant influence on FFA and TSA, which are measured on short lateral films. TVA measurements on the full frontal x-ray are also affected by difficulty in indicating implant line where for a femoral implant a line tangent to the condyles is more consistent. These results can be compared to the findings of Hirschmann et al [2] where, contrary to their data, our measurements on FVA and TVA correlate better, presumably because of the use of long leg film instead of short film. Our data is collected from 6 surgeons whereas the Hirschmann et al study represents 1 surgeon and 1 radiologist. SDC calculations based on this variability study show the smallest detectable changes on x-ray measurements for FVA, TVA and TSA are approximately 1° and approximately 2° for FFA. Conclusion. The results indicate that x-ray measurement variability should be taken into account when choosing a post-operative measurement technique. While x-ray measurement still has its place in daily practice, we advise more consistent methods of measuring for research


The Bone & Joint Journal
Vol. 101-B, Issue 8 | Pages 984 - 994
1 Aug 2019
Rua T Malhotra B Vijayanathan S Hunter L Peacock J Shearer J Goh V McCrone P Gidwani S

Aims. The aim of the Scaphoid Magnetic Resonance Imaging in Trauma (SMaRT) trial was to evaluate the clinical and cost implications of using immediate MRI in the acute management of patients with a suspected fracture of the scaphoid with negative radiographs. Patients and Methods. Patients who presented to the emergency department (ED) with a suspected fracture of the scaphoid and negative radiographs were randomized to a control group, who did not undergo further imaging in the ED, or an intervention group, who had an MRI of the wrist as an additional test during the initial ED attendance. Most participants were male (52% control, 61% intervention), with a mean age of 36.2 years (18 to 73) in the control group and 38.2 years (20 to 71) in the intervention group. The primary outcome was total cost impact at three months post-recruitment. Secondary outcomes included total costs at six months, the assessment of clinical findings, diagnostic accuracy, and the participants’ self-reported level of satisfaction. Differences in cost were estimated using generalized linear models with gamma errors. Results. The mean cost up to three months post-recruitment per participant was £542.40 (. sd. £855.20, n = 65) for the control group and £368.40 (. sd. £338.60, n = 67) for the intervention group, leading to an estimated cost difference of £174 (95% confidence interval (CI) -£30 to £378; p = 0.094). The cost difference per participant increased to £266 (95% CI £3.30 to £528; p = 0.047) at six months. Overall, 6.2% of participants (4/65, control group) and 10.4% of participants (7/67, intervention group) had sustained a fracture of the scaphoid (p = 0.37). In addition, 7.7% of participants (5/65, control group) and 22.4% of participants (15/67, intervention group) had other fractures diagnosed (p = 0.019). The use of MRI was associated with higher diagnostic accuracy both in the diagnosis of a fracture of the scaphoid (100.0% vs 93.8%) and of any other fracture (98.5% vs 84.6%). Conclusion. The use of immediate MRI in the management of participants with a suspected fracture of the scaphoid and negative radiographs led to cost savings while improving the pathway’s diagnostic accuracy and patient satisfaction. Cite this article: Bone Joint J 2019;101-B:984–994


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIX | Pages 178 - 178
1 Sep 2012
Heaver C Mart JS Nightingale P Sinha A Davis E
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Aims. Leg length inequality following total hip replacement remains common. In an effort to reduce this occurrence, surgeons undertake pre-operative templating and use various forms of intra-operative measurements, including computer navigation. This study aims to delineate which measurement technique is most appropriate for measuring leg length inequality from a pelvic radiograph. Method. Three observers took a total of 9600 measurements from 100 pelvic radiographs. Four lines were constructed on each of the radiographs, bisecting the acetabular teardrops (Methods 1/2), ishial spines (Method 3/4), inferior sacroiliac joint (Method 5/6) and inferior obturator foramen (Method 7/8). Measurements were taken from these lines to the midpoint on the LT and to the tip of the GT. The effect of pelvic positioning was also assessed using radiographs of a synthetic pelvis and femur using the same eight methods by a single observer (ED). Intra-observer variability was analysed using within subject standard deviation. Inter-observer variability was analysed using the coefficient of inter-observer variability (CIV). Results. When considering the 100 pelvic radiographs measurement methods 3 (SD 3.5, CIV 0.34) and 8 (SD 3.3 CIV 0.33) showed the best inter and intra observer variability. Methods 4 and 6 performed badly for inter and intra observer variability (SD 3.8 CIV 0.4 and SD 4.6 CIV 0.4). Methods 1, 2, 5 and 7 performed well in one aspect but poorly in the other. When considering the effect of pelvic positioning using radiographs of the synthetic pelvis and femur construct, methods 3 and 7 performed best (SD 6.7 and SD 7.4). Discussion. Measuring from the ischial tuberosities to the LT has the best intra- and interobserver variability. It also performs well despite pelvic malposition. As techniques improve in the measurement of intra-operative leg length, a more accurate measurement of leg length is needed to validate these technologies by


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_1 | Pages 50 - 50
1 Jan 2017
Rutherford M Hill J Beverland D Lennon A Dunne N
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Anterior-posterior (AP) x-rays are routinely taken following total hip replacement to assess placement and orientation of implanted components. Pelvic orientation at the time of an AP x-ray can influence projected implant orientation. 1. However, the extent of pelvic orientation varies between patients. 2. Without compensation for patient specific pelvic orientation, misleading measurements for implant orientation may be obtained. These measurements are used as indicators for post-operative dislocation stability and range of motion. Errors in which could result in differences between expectations and the true outcome achieved. The aim of this research was to develop a tool that could be utilised to determine pelvic orientation from an AP x-ray. An algorithm based on comparing projections of a statistical shape model of the pelvis (n=20) with the target X-ray was developed in MATLAB. For each iteration, the average shape was adjusted, rotated (to account for patient-specific pelvic orientation), projected onto a 2D plane, and the simulated outline determined. With respect to rotation, the pelvis was allowed to rotate about its transverse axis (pelvic flexion/extension) and anterior-posterior axis (pelvic adduction/abduction). Minimum root mean square error between the outline of the pelvis from the X-ray and the projected shape model outline was used to select final values for flexion and adduction. To test the algorithm, virtual X-rays (n=6) of different pelvis in known orientations were created using the algorithm described by Freud et al. 3. The true pelvic orientation for each case was randomly generated. Angular error was defined as the difference between the true pelvic orientation and that selected by the algorithm. Initial testing has exhibited similar accuracy in determining true pelvic flexion (x̄error = 2.74°, σerror=±2.21°) and true pelvic adduction (x̄error = 2.38°, σerror=±1.76°). For both pelvic flexion and adduction the maximum angular error observed was 5.62°. The minimum angular error for pelvic flexion was 0.37°, whilst for pelvic adduction it was 1.08°. Although the algorithm is still under development, the low mean, maximum, and standard deviations of error from initial testing indicate the approach is promising. Ongoing work will involve the use of additional landmarks for registration and training shapes to improve the shape model. This tool will allow surgeons to more accurately determine true acetabular orientation relative to the pelvis without the use of additional x-ray views or CT scans. In turn, this will help improve diagnoses of post-operative range of motion and dislocation stability


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_1 | Pages 72 - 72
1 Jan 2018
O'Connor J Hill J Beverland D Dunne N Lennon A
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This study aimed to assess the effect of flexion and external rotation on measurement of femoral offset (FO), greater trochanter to femoral head centre (GT-FHC) distance, and neck shaft angle (NSA). Three-dimensional femoral shapes (n=100) were generated by statistical shape modelling from 47 CT-segmented right femora. Combined rotations in the range of 0–50° external and 0–50° flexion (in 10° increments) were applied to each femur after they were neutralised (defined as neck and proximal shaft axis parallel with detector plane). Each shape was projected to create 2D images representing radiographs of the proximal femora. As already known, external rotation resulted in a significant error in measuring FO but flexion alone had no impact. Individually, neither flexion nor external rotation had any impact on GT-FHC but, for example, 30° of flexion combined with 50°of external rotation resulted in an 18.6mm change in height. NSA averaged 125° in neutral with external rotation resulting in a moderate increase and flexion on its own a moderate decrease. However, 50° degrees of both produced an almost 30 degree increase in NSA. In conclusion, although the relationship between external rotation and FO is appreciated, the impact of flexion with external rotation is not. This combination results in apparent reduced FO, a high femoral head centre and an increased NSA. Femoral components with NSAs of 130° or 135° may historically have been based on X-ray misinterpretation. This work demonstrates that 2D to 3D reconstruction of the proximal femur in pre-op planning is a challenge


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_6 | Pages 8 - 8
1 Mar 2017
Sim J Lee B
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Introduction. Well-balanced soft tissue is essential for achieving a good result when performing total knee arthroplasty. The preoperative planning is critical for ensuring a good operation. This study evaluated the preoperative distractive stress radiographs in order to quantify and predict the extent of medial release according to the degree of varus deformity in primary total knee arthroplasty. Methods. We evaluated 120 varus, osteoarthritic knee joints (75 patients). The association of the angle on the distractive stress radiograph with extent of medial release was analyzed. The extent of medial release was classified into the following 4 groups according to the stage: release of the deep medial collateral ligament (group 1), release of the posterior oblique ligament and/or semimembranous tendon (group 2), release of the posterior capsule (group 3) and release of the superficial medial collateral ligament (group 4). Results. Of the 120 cases for which medial release was performed, 30 (25.0%), 41 (34.2%), 20 (16.7%), and 29 (24.2%) cases were in group 1, 2, 3, and 4, respectively. After medial release, the difference between the medial and lateral gaps in flexion and extension was 0.1 mm (range, 0 to 1 mm) and 0.1 mm (range, 0 to 1 mm), respectively. The difference between the flexion and extension gaps was 0.6 mm (range, 0 to 1.5 mm). The mean femorotibial angle on the preoperative distractive stress radiograph was valgus 2.4° (group 1), valgus 0.8° (group 2), varus 2.1° (group 3) and varus 2.7° (group 4). The extent of medial release increased with increasing degree of varus deformity seen on the preoperative distractive stress radiograph.(Figure 1). Conclusions. The preoperative distractive stress radiograph was useful for predicting the extent of medial release when performing primary total knee arthroplaty. For any figures or tables, please contact authors directly (see Info & Metrics tab above).


The Journal of Bone & Joint Surgery British Volume
Vol. 88-B, Issue 11 | Pages 1508 - 1512
1 Nov 2006
Wimsey S Pickard R Shaw G

Magnification of anteroposterior radiographs of the pelvis is variable. To improve the accuracy of templating, reliable and radiographer-friendly methods of scaling are necessary. We assessed two methods of scaling digital radiographs of the pelvis: placing a coin of known diameter in the plane of interest between the patient’s thighs, and using a caliper to measure the bony width of the pelvis. A total of 39 patients who had recently undergone hemiarthroplasty of the hip or total hip replacement were enrolled in the study. The accuracy of the methods was assessed by comparing the actual diameter of the head of the prosthesis with the measured on-screen value. The coin method was within a mean of 1.12% (0% to 2.38%) of the actual measurement, the caliper group within 6.99% (0% to 16.67%). The coin method was significantly more accurate (p < 0.001). It was also reliable and radiographer friendly. We recommend it as the method of choice for scaling radiographs of the pelvis before hip surgery


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XLIV | Pages 38 - 38
1 Oct 2012
Weidert S Wang L Thaller P Landes J Brand A Navab N Euler E
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The verification of the alignment of the lower limb is critical for reconstructive surgery as well as trauma surgery in order to prevent osteoarthritis. The mechanical axis is a straight line defined by the center of the femoral head and the center of the ankle joint, ideally passing the knee joint in its center. Whereas the usual preoperative method to determine the mechanical axis of the lower limbs is still the long standing radiograph, common intra-operative methods are the use of an electrocautery cord or an X-ray grid consisting of wire lines underneath the patient. Both methods require the surgeon to bring the femoral head and the ankle joint exactly to overlay with a radiopaque line that passes through both points. The distance of the knee center from this line is defined as the mechanical axis deviation (MAD). In order to reduce the errors introduced by perspective projection effects, the joint centers must be placed in the center of the c-arm images, which definitely requires time, experience and additional radiation. We propose a computer aided X-ray stitching method that puts individual X-ray images into a panoramic image frame combining the Camera Augmented Mobile C-arm (CamC) system, which features a video camera with its optical center virtually coinciding with the origin of the X-rays, with an optical tracking marker pattern underneath the operating table. The camera image of the marker pattern is used to perform pose estimation of the C-arm, allowing the calculation of the x-ray source motion between the positions in which the individual X-rays were taken. By estimating the homography, the different X-rays can be registered into a panoramic frame, enabling perfect alignment and metric measurements. In order to reduce parallax effects that lead to axis and metric measurement errors, we applied a method requiring two constraints: The bone plane has to be roughly parallel to the planar marker pattern and the distance between the marker plane and the bone plane has to be estimated. In order to evaluate the method, we used a life-size synthetic skeleton leg. After tightening a straight wire between the centers of the hip and ankle joint, the knee joint was bent into a MAD of 55 mm, which was confirmed by measuring the distance between the knee center and the wire with a ruler. The leg phantom was then placed on a radiolucent operating table, parallel to the pattern plane 130 mm underneath. The operating table was moved through the C-arm while acquiring the three desired X-ray images. which were registered into a panoramic image frame. The centers of the femoral head, the ankle, and the knee were manually determined on the generated panoramic image by a surgeon. The mechanical axis was automatically displayed and the MAD was visualised in the image and computed as 55.23 mm. We presented a new solution to intra-operatively verify alignment of the lower extremity. When using the CamC system, only a marker pattern has to be used for tracking. No additional tracking devices and calibration procedures are needed. Furthermore, the presented method only requires three x-rays that cover the femoral head, the knee and the ankle and marking of the three spots. Due to the parallax correction, these spots do not have to be exactly in the center of the picture. For this reason, compared to using an X-ray grid or an electrocautery cord, our method allows the procedure to be much faster and reduces the number of x-ray images. However, for clinical evaluation, a patient study will be conducted in the future


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_3 | Pages 112 - 112
1 Feb 2017
Faizan A Chuang P Aponte C Sharkey P
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Introduction. Various 2D and 3D surfaces are available for cementless fixation of acetabular cups. The goal of these surface modifications is to improve fixation between the metallic cups and surrounding bone. Radiographs have historically been used to evaluate the implant-to-bone fixation around the acetabular cups. In general, a well fixed cup shows no gaps or radiolucency around the cup's outer diameter. In post-operative radiographs, the presence of progressive radiolucent zones of 2mm or more around the implant in the three radiographic zones is indicative of aseptic loosening, as described by DeLee and Charnley [1]. In this cadaveric study, we investigated the X-ray image characteristics of two different types of acetabular shell surfaces (2D and 3D) to evaluate the implant-to-bone interface in the two designs. Methods. Six human cadavers were bilaterally implanted with acetabular cups by an orthopaedic surgeon. 2D surface cups (Trident, Stryker, Mahwah, NJ) and 3D surface cups (Tritanium, Stryker, Mahwah, NJ) were randomized between the left and right acetabula. The surgeon used his regular surgical technique (1 mm under reaming) to implant the acetabular cups. The cadavers were sent for X-ray imaging after the operation, Figure 1A. Following the X-ray imaging, the acetabular cups were carefully resected from the cadavers. Enough bone around the cups was retained for analysis of the implant-to-bone interface by contact X-ray. The acetabular cups with the surrounding bone were fixed in 70% isopropyl alcohol for about a week and subsequently embedded in polymethyl methacrylate. The embedded cups were sectioned at 30° intervals using a diamond saw in the coronal plane, as recommended by Engh et al [2], Figure 1B. The sectioning of the samples produced 6 slices of each cup where the implant-bone interface could easily be visualized for evaluation with contact X-ray. Results. The AP X-rays of the cadavers demonstrated radiolucent lines, as well as gap defects in some cases. The same phenomenon was observed on the contact X-rays of the embedded implant sections as well, where one could easily identify the gap between the metal cup and the surrounding bone. The most striking finding was that, in a few cases, the contact X-rays showed radiolucency around the metal cup whereas the physical section did not seem to have any gaps. This phenomenon is illustrated in Figure 2. Conclusions. The physical gap or radiolucent lines around the acetabular cups have been reported in literature; however, they seem to fill up with time as biological fixation progresses between the surrounding bone and the implant. In our study we found radiolucency that was not associated with the presence of a physical gap. In contrast, we found gaps on physical sections that were not correlated with radiolucencies. This phenomenon may be attributed to the interaction of X-rays with the cup surface modifications. The contact X-ray images demonstrated that radiolucency around cups may not always correlate with physical gaps. Further analysis is required to understand the implications of these findings


The Bone & Joint Journal
Vol. 101-B, Issue 11 | Pages 1416 - 1422
1 Nov 2019
Rohilla R Sharma PK Wadhwani J Rohilla S Beniwal R Singh R Devgan A

Aims. In this randomized study, we aimed to compare quality of regenerate in monolateral versus circular frame fixation in 30 patients with infected nonunion of tibia. Patients and Methods. Both groups were comparable in demographic and injury characteristics. A phantom (aluminium step wedge of increasing thickness) was designed to compare the density of regenerate on radiographs. A CT scan was performed at three and six months postoperatively to assess regenerate density. A total of 30 patients (29 male, one female; mean age 32.54 years (18 to 60)) with an infected nonunion of a tibial fracture presenting to our tertiary institute between June 2011 and April 2016 were included in the study. Results. The regenerate mineralization on radiographs was comparable in both groups at two, four, six, and ten months’ follow-up but the rail fixator group had statistically significant higher grades of mineralization when compared with the circular frame group at eight and 12 months’ follow-up. The regenerate mineralization was also higher in the rail fixator group than in the circular frame group on CT at three and six months, although this difference was not statistically significant. Conclusion. Overall, the regenerate mineralization was higher in the monolateral than the circular frame group. A monolateral fixator may be preferred in patients with infected nonunion of the tibia with bone defects up to 7 cm. Cite this article: Bone Joint J 2019;101-B:1416–1422


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_5 | Pages 35 - 35
1 Feb 2016
Hsu J de la Fuente M Radermacher K
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For a successful total knee arthroplasty (TKA) and long prosthesis lifespan, correct alignment of the implant components as well as proper soft tissue balancing are of major importance. In order to overcome weaknesses of existing imaging modalities for TKA planning such as radiation exposure and lack of soft tissue visualisation (X-ray and CT) and high cost, long acquisition times and geometric distortion (MRI), it is investigated if ultrasound (US) imaging is a suitable alternative. Currently, a reconstruction method of the bony knee morphology based on US imaging is developed at our research institute. For capturing the mechanical axis, being crucial for TKA planning, different approaches could be implemented. This work investigates whether a weight-bearing full leg X-ray registered with the local 3D-US knee dataset can be used for this purpose. Also, the impact of incorrect calibration data (i.e. uncalibrated X-rays) on the accuracy of the estimated mechanical axis is investigated. A 3D-2D projective, feature-based registration algorithm was used to spatially align the 3D US-based model to the 2D X-ray image before transferring the mechanical axis from the X-ray to the model. For validation, a CT-based local model and its projection were used and an initial error in translation and rotation was added. Also, calibration parameters such as the centre ray position and the source-to-image-detector distance were altered. The estimation error of the mechanical axis was less than 1°, the median error lower than 0.1° in the frontal plane. Even if the calibration data is not available, the accuracy remains sufficient for TKA planning. In this study, idealised 2D and 3D image information was used. In the future, this method should be tested using clinical X-ray images and 3D-US data


The Journal of Bone & Joint Surgery British Volume
Vol. 72-B, Issue 4 | Pages 639 - 640
1 Jul 1990
Messieh S Fowler P Munro T

Destruction of the articular cartilage is the first change seen on gross examination of the knee in osteoarthritis. Weight-bearing radiographs are conventionally taken with the knee in full extension. Biomechanical studies have shown, however, that the major contact stresses in the femorotibial articulation occur when the knee is flexed about 28 degrees. Arthroscopy has confirmed that cartilage loss occurs in a more posterior portion of the femoral condyles than is revealed by radiographs taken in full extension. The 'standing tunnel view' is a weight-bearing postero-anterior radiograph taken with the knee in 30 degrees of flexion. The radiographs of 64 patients have been used to compare the conventional with the standing tunnel view. In 10 knees in which the conventional view suggested normal cartilage the standing tunnel view revealed severe degeneration


The Bone & Joint Journal
Vol. 95-B, Issue 4 | Pages 472 - 477
1 Apr 2013
Liebs T Kloos S Herzberg W Rüther W Hassenpflug J

We investigated whether an asymmetric extension gap seen on routine post-operative radiographs after primary total knee replacement (TKR) is associated with pain at three, six, 12 and 24 months’ follow-up. On radiographs of 277 patients after primary TKR we measured the distance between the tibial tray and the femoral condyle on both the medial and lateral sides. A difference was defined as an asymmetric extension gap. We considered three groups (no asymmetric gap, medial-opening and lateral-opening gap) and calculated the associations with the Western Ontario and McMaster Universities osteoarthritis index pain scores over time. Those with an asymmetric extension gap of ≥ 1.5 mm had a significant association with pain scores at three months’ follow-up; patients with a medial-opening extension gap reported more pain and patients with a lateral-opening extension gap reported less pain (p = 0.036). This effect was still significant at six months (p = 0.044), but had lost significance by 12 months (p = 0.924). When adjusting for multiple cofounders the improvement in pain was more pronounced in patients with a lateral-opening extension gap than in those with a medial-opening extension gap at three (p = 0.037) and six months’ (p = 0.027) follow-up. Cite this article: Bone Joint J 2013;95-B:472–7


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IX | Pages 61 - 61
1 Mar 2012
Donaldson OW Heal J Mulford J Wakeley CJ Eldridge JDJ
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The purpose of our study was to assess the reproducibility and reliability of traditional radiographic methods of diagnosing trochlear dysplasia compared with the gold standard of MRI. Plain radiographs and MRI scans of 36 knees in 28 patients with proven trochlear dysplasia were compared with 18 controls in a single surgeon's practice. The sulcus angle on MRI and axial radiographs was measured. The lateral radiograph was assessed for adequacy, the crossing sign and the trochlear bump sign. The mean axial (radiograph) and MRI sulcus angles in the dysplastic group were 145° and 158° respectively (p=0.0001) compared to 135° and 138° in the control group (p=0.09). The crossing sign was present in 34 out of 36 lateral radiographs in the dysplastic group and 8 out of 18 in the control group equating to a sensitivity of 94% and specificity of 56%. The quality of the lateral radiograph did not significantly alter the sensitivity or specificity of the crossing sign (p=0.01). The bump sign was present in 22 out of 36 lateral radiographs in the dysplastic group and 1 out of 18 in the control group equating to a sensitivity of 61% and specificity of 94%. Our study shows that an increased radiographic sulcus angle is reliable in diagnosing trochlear dysplasia but underestimates it. The bump sign is a reliable predictor of trochlear dysplasia. The crossing sign is sensitive but not specific in diagnosing dysplasia


The Journal of Bone & Joint Surgery British Volume
Vol. 72-B, Issue 1 | Pages 98 - 101
1 Jan 1990
Dias J Thompson J Barton N Gregg P

Twenty observers reported independently on the presence or absence of a fracture of the scaphoid on 60 sets of radiographs; these included initial and 2- to 3-week views in patients in whom the outcome was known, normal scaphoids and random copies of these. Analysis of variance of the accuracy of observations revealed that the 2- to 3-week radiographs did not improve diagnostic ability and that this was independent of the experience or seniority of the observer. For normal radiographs, 20% of the observations reported a fracture. Reproducibility of opinion improved with experience but this did not help with accuracy. Radiographs without accurate clinical observation should not determine the management of the suspected scaphoid fracture


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_6 | Pages 18 - 18
1 Apr 2018
Guan S Gray H Schache A Feller J de Steiger R Pandy M
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INTRODUCTION. Accurate knowledge of knee joint kinematics following total knee arthroplasty (TKA) is critical for evaluating the functional performance of specific implant designs. Biplane fluoroscopy is currently the most accurate method for measuring 3D knee joint kinematics in vivo during daily activities such as walking. However, the relatively small imaging field of these systems has limited measurement of knee kinematics to only a portion of the gait cycle. We developed a mobile biplane X-ray (MoBiX) fluoroscopy system that enables concurrent tracking and imaging of the knee joint for multiple cycles of overground gait. The primary aim of the present study was to measure 6-degree-of-freedom (6-DOF) knee joint kinematics for one complete cycle of overground walking. A secondary aim was to quantify the position of the knee joint centre of rotation (COR) in the transverse plane during TKA gait. METHODS. Ten unilateral posterior-stabilised TKA patients (5 females, 5 males) were recruited to the study. Each subject walked over ground at their self-selected speed (0.93±0.12 m/s). The MoBiX imaging system tracked and recorded biplane X-ray images of the knee, from which tibiofemoral kinematics were calculated using an image processing and pose-estimation pipeline created in MATLAB. Mean 6-DOF tibiofemoral joint kinematics were plotted against the mean knee flexion angle for one complete cycle of overground walking. The joint COR in the transverse plane was calculated as the least squares intersection of the femoral flexion axis projected onto the tibial tray during the stance and swing phases. The femoral and tibial axes and 6-DOF kinematics were defined in accordance with the convention defined by Grood and Suntay in 1983. RESULTS AND DISCUSSION. The offset in secondary joint motions at a given flexion angle was greater at larger knee flexion angles than at smaller flexion angles for abduction, anterior drawer, and lateral shift, whereas the opposite was true for external rotation. Significant variability was observed between subjects for the COR. The mean COR was on the lateral side during stance, consistent with results reported in the literature for the intact knee. Interestingly, the mean COR was on the medial side during swing. CONCLUSIONS. Our results suggest that secondary joint motions in the TKA knee, specifically, external rotation, abduction, anterior drawer and lateral shift, are determined not only by implant geometry and ligament anatomy but also by external loading, and are therefore task-dependent. The mean COR in the transverse plane shifted from the lateral to the medial side of the knee as the leg transitioned from stance to swing. Mobile dynamic X-ray imaging is a valuable tool for evaluating the functional performance of knee implants during locomotion over ground


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XLIV | Pages 26 - 26
1 Oct 2012
Lubovsky O Safran O Axelrod D Peleg E Whyne C
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Fractures of the clavicle are relatively common, occurring mostly in younger patients and have historically been managed non-operatively. Recent studies have shown an advantage to surgical reduction and stabilisation of clavicle fractures with significant displacement. Currently, fracture displacement is measured using simple anterior-posterior two-dimensional x-rays of the clavicle. Since displacement can occur in all three-dimensions, however, evaluation of the amount displacement can be difficult and inaccurate. The purpose of this study was to determine the view that provides the most accurate assessment. Nine CT scans of acute displaced clavicle fractures were analysed with AmiraDEV5.2.2 Imaging software. Measurements for degrees of shortening and fracture displacement of the fracture clavicle were taken. Using a segmentation and manipulation module (ITK toolkit), five digitally reconstructed radiographs (DRRs) mimicking antero-posterior x-rays were created for every CT, with each differing by projection angle (ranging from 20° upwards tilt to 20° downwards tilt). Measurements were taken on each DRR using landmarks of entire clavicle length, distance from vertebrae to fracture (medial fragment length), distance from fracture to acromium (lateral fragment length), and horizontal shortening, and then compared to the true measurement obtained from the original CT. For all 9 samples, after comparing the measurements of clavicle fracture displacement in each 2D image, we found that an AP view with a 20° downward tilt yielded displacement measurements closest to the 3D (“gold standard”) measurements. The results agree with previous data collected from cadaveric specimens using physical X-ray film images. DDRs enable creation of multiple standard AP radiographs from which accurate tilt can be measured. The large deviation in measurements on different DRR projections motivates consideration of standardising X-ray projections. A uniform procedure would allow one to correctly evaluate the displacement of clavicular fractures if fracture displacement information is to be utilized in motivating surgical decision-making


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_III | Pages 404 - 404
1 Jul 2010
Taylor D McManus Y Day N Sharma H
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Introduction: Obtaining adequate images can be difficult in ring fixator patients during outpatient follow-up. Following a recent publication, we introduced the spirit level technique as an effective method to ensure better quality images for interpretation, reduce unnecessary x-ray exposure, and improve clinic efficiency. Method: A comparison was made of radiograph quality, patient inconvenience and x-ray exposure between standard X-ray techniques and those with a frame mounted spirit-level in all patients attending the senior author’s outpatient clinic for routine follow up following Ilizarov and Taylor-Spatial frames. Prospective data was collected using a paper proforma in frame clinic. Information was gathered on all patients sent for plain radiographs. Radiographers collected data regarding time taken in the X-ray Department and total number of radiographs taken to gain the images required. The senior author recorded if these images were satisfactory and if returned to the department for further imaging. The radiation dose was retrieved from the Radiology computer. The control group consisted of patients from clinics prior to implementation of the spirit-level device. Following a period of familiarization, data was collected from the study group using the spirit-level. Results: (Table deleted). Conclusion: The implementation of a simple frame mounted spirit-level as a guide for the radiographers in the outpatient clinic improves x ray quality, to assess healing, and significantly reduces the number of suboptimal images. The data does not support a significant impact on patient inconvenience


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_20 | Pages 12 - 12
1 Dec 2017
Yu AW Zheng BG
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Accurate 3D pre-operative planning shows significance of improving the precision of Total Hip Arthroplasty (THA) and Total Knee Arthroplasty (TKA). Since CT acquisition leads to high radiation exposure to patients, it is clinically desirable to find an alternative to CT scan for planning THA or TKA such as patient-specific 2D–3D reconstruction from a limited number of 2D calibrated X-ray images acquired with much lower radiation dose e.g. EOS imaging. Feature-based 2D–3D non-rigid registration based on the construction of statistical shape model (SSM) as a priori has been applied to reconstruct the surface models of proximal femur, and also the surface reconstruction of lower extremity for TKA has been validated in a cadaveric study by Zheng et al. On the other hand, intensity-based 2D–3D non-rigid registration can reconstruct the patient-specific intensity volumes like CTs to allow an insight into lower extremity morphology such as intramedullary anatomy, which can provide more comprehensive information in routine clinical practice. In this study, we will present an atlas- based 2D–3D reconstruction method and introduce its application to reconstruct the intensity volumes of lower extremity. Moreover, we take the articulation in the knee joint into consideration so as to avoid the penetration between femur and tibia which is favourable for the pre-operative planning. The results of the experiments demonstrated the efficacy of the proposed method on reconstructing the lower extremity morphology as well as the intramedullary canal anatomy


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_II | Pages 164 - 164
1 Feb 2003
Haslam P Nimagadda S Redden J
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To compare the results of anterior cruciate ligament reconstructive surgery with or without fluoroscopic control. We retrospectively compared 2 groups of 15 patients who had ACL reconstruction between 1997–2001. Our primary concern was to see if a perioperative lateral x-ray significantly improved the position of the graft when compared with a similar group having no such x-ray. All patients were reconstructed using an open bone-patella-bone technique. Data was collected on patient demographics, previous surgery, time to reconstruction, operative time, and complications. The post–operative lateral x-ray was assessed and the relative position of the centre of the graft determined using a percentage for the tibial and femoral tunnels. The graft divergence angle and distance between the posterior femoral cortex and the centre of the graft was calculated. All patients were male with equal mean age at reconstruction (29 yrs). The 2 groups were also similar in terms of previous surgery and time to reconstruction. In the group without x-ray control there were 2 graft failures due to anterior placement of the graft whereas in the x-ray control group there were no failures. The operative time was slightly longer in the x-ray group. There was no significant difference between the 2 groups when comparing tibial tunnel placement and graft divergence. However the position of the femoral tunnel was significantly improved in the x-ray group when compared with the control group as measured by the distance between posterior femoral cortex and centre of graft (7mm vs 9mm) and also the relative position along Blumenstaat’s line (90% vs 75%). The authors conclude that in our institution the use of Fluoroscopic control during ACL reconstructive surgery improved femoral tunnel placement


Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_3 | Pages 15 - 15
1 Feb 2014
Bugler K Smith G White T
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Assessment of stability in ankle fractures is key in deciding the most appropriate mode of treatment. Stress radiographs have been suggested as a potential method for assessing ankle stability in patients with apparently isolated lateral malleolar fractures. Whilst stress radiographs have been found to be both sensitive and specific in cadaveric experiments, recent clinical studies have suggested that a widened medial clear space (MCS) on stress radiographs may not equate to a functionally unstable ankle. We aimed to assess whether patients with an apparently isolated lateral malleolar fracture on presentation but with a positive gravity stress radiograph (GSR) could be successfully managed non-operatively. A prospective study of all patients with lateral malleolar fractures presenting to our orthopaedic trauma department was undertaken. Patients with an oblique distal fibular fracture pattern and no obvious MCS widening on routine radiographs underwent a GSR. Measurements of the radiographic MCS and superior clear space (SCS) were made and compared with published criteria. 155 patients were included in the study and treated non-operatively fully weight bearing in either a cast or removable boot. Following fracture union all patients had both anatomical alignment of the ankle mortise and good or excellent function. The MCS of 79% of these patients was found to be greater than 4 mm with 19% greater than 6 mm. All of these patients were successfully managed non-operatively. The currently used criteria for measurements on stress radiographs result in high numbers of false positive cases. This may be leading to unnecessary surgery. Further investigation is required in order to identify other clinical or radiographic criteria that may be of use in the assessment of functional ankle stability after fracture


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_1 | Pages 64 - 64
1 Jan 2017
Somodi S Andersen K Ebskov L Rasmusen P Muharemovic O Penny J
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The CCI mobile bearing ankle implant used at our orthopedic department 2010–2013, was abandoned due to failures and findings of bone loss at revision. The aim of this study was to a) Determine our true revision rate, b) Investigate accuracy of measuring prevalence, size and location of periprosthetic bone cysts through X-ray and CT and c) Relate these findings to implant alignment and patient reported outcome measurements (PROMs). 51 primary surgeries were performed, prior to this study 8 had been revised. Out of 43 un-revised patients, 36 were enrolled and underwent evaluation with metal artefact reduction CT-scans and conventional X-ray. They filled out 3 PROMs; SEFAS, SF-12, EQ-5D. Cyst volume larger than 0.1 ml was measured using VITREA volume tools for CT-scans and calculation of spherical volume for X-rays; using AP- and lateral projections. Location of lesions was recorded, according to their position relative to the implant. Medial-/lateral- and anterior-/posterior tilt of the implant parts was measured using IMPAX built in measuring tools, applied to AP- and lateral X-ray projection. The relation between lesions location and alignment of components was analyzed by logistic regression. Bias and ICC estimation between CT and X-ray was analyzed by mixed effect model. Log transformation was used to fit the normal distribution assumption. PROMs association to osteolytic volume was analyzed by linear- and logistic regression. P-values of 0.05 were considered statistically significant. Finding large osteolytic lesions caused 4 additional patients to undergo revision and 7 are being monitored due to high risk of failure. Of the original 51 implants 14 have been revised. 8 cases because of osteolytic lesions and aseptic loosening (true revisions w. exchange of components or bone transplants), 3 periprosthetic fractures (2 non-traumatic fractures) and 3 cases of exostosis. The 3- and 5 year revision rate was 14% and 16% for true revisions and 17% and 27% overall. Cystic lesions were found in 81% of participants. Total cyst-volume was on average 13% larger on X-ray, however this difference was not significant (p = 0.55), with intraclass correlation being 0.66. Total cystic volume was not significantly related to PROM-scores (P 0.16–0.5). Location of cysts showed association with alignment of components (P 0.02–0.08). Mean tibia component anterior tilt was 89 degrees (SD 4). Mean medial tilt was 91 degrees (SD 3) for the tibial and 90 degrees (SD 4) for the talar component. The implant investigated performs below standard, compared to public registries. 1, 2. that report overall 5 year revision rates at 5 – 6.5%. We obtained larger measurements from X-rays than CT, unlike previous studies comparing these modalities. Cysts were common and large. Correlation between lesion location and alignment of implant, with valgus and anterior tilt of components causing more lesions in adjacent zones, may suggest a link between implant failure and alignment of components


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_34 | Pages 598 - 598
1 Dec 2013
Yamazaki T Kamei R Yoshikawa H Sugamoto K
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Purpose:. To materialize 3D kinematic analysis of total knee arthroplasty (TKA), 2D/3D registration techniques, which use X-ray fluoroscopic images and the knee implants CAD, have been applied to clinical cases. However, most conventional methods have needed time-consuming and labor-intensive manual operations in some process. In previous study, we addressed a manual operations problem when setting initial pose of implants model for 2D/3D registration, and reported a semi-automated initial pose estimation method based on an interpolation technique. However, this method still required appropriate initial pose estimation of the model with manual operations for some X-ray images (key frames). Additionally, in the situation like fast knee motion and use of low frame rate, good registration results were not obtained because of the large displacement between each frame silhouette. To overcome these problems, this study proposes an improved semi-automated 3D kinematic estimation method. Methods:. Our 2D/3D registration technique is based on a robust feature-based algorithm. In improved initial pose estimation method, for the only first frame, the initial pose is manually adjusted as close as possible. That is, we automatically estimate appropriate initial pose of the model for X-ray images except for the first frame. To automatically estimate the initial pose of the model, we utilize a transformation with feature points extracted from the previous and next frames. A transform matrix which has three DOF (translations parallel to the image, and a rotation perpendicular to the image) is calculated by registration of corresponding feature points between the previous and next frame extracted with SURF algorithm. While, the corresponding point sets extracted by SURF sometimes include some error sets. Therefore, in this study, LmedS method was employed to detect the error corresponding sets and calculate a transform matrix accurately. In Fig. 1(a) and (b), the orange square shows the region defined with the boundary box of the model, and some lines show the combined corresponding point sets. The blue lines are correct corresponding point sets, and the pink lines are error corresponding point sets detected with LmedS method. Finally, 3D pose of the model estimated in previous frame is transformed with accurately calculated transform matrix, and the transformed pose is used as an initial 3D pose of the model in next frame. Experimental results:. To validate the feasibility of the improved semi-automated 3D kinematic estimation method, experiments using X-ray fluoroscopic images of 4 TKA patients during knee motions were performed. In order to assess the performance of the improved method, automation rate was calculated, and the rate was defined as the X-ray frame number of satisfying clinical required accuracy (error within 1 mm, 1 degree) relative to all X-ray frame number. As results of the experiments, 3D pose of the model for all X-ray images except for the first frame is automatically stably-estimated, the automation rate of the femoral and tibial component were 83.7% and 73.5%, respectively. Conclusions:. The present method doesn't need labor-intensive manual operations for 3D kinematic estimation of TKA, and is thought to be very helpful for practical clinical applications