Aims. Despite the interest in the association of gut microbiota with bone health, limited population-based studies of gut microbiota and
Objectives. The goal of this study is to investigate the relation between indicators of osteoporosis (i.e.,
Aims. Osteoporosis and abnormal bone metabolism may prove to be significant
factors influencing the outcome of arthroplasty surgery, predisposing
to complications of aseptic loosening and peri-prosthetic fracture.
We aimed to investigate baseline
Purpose. The purpose of this study was to evaluate periprosthetic
We studied the
In patients with osteoporosis there is always
a strong possibility that pedicle screws will loosen. This makes
it difficult to select the appropriate osteoporotic patient for
a spinal fusion. The purpose of this study was to determine the
correlation between
We compared peri-prosthetic
The major advantage of hip resurfacing is the decreased amount of bone resection compared with a standard total hip replacement. Fracture of the femoral neck is the most common early complication and poor bone quality is a major risk factor. We undertook a prospective consecutive case control study examining the effect of
Low-energy fractures of the proximal humerus indicate osteoporosis and it is important to direct treatment to this group of patients who are at high risk of further fracture. Data were prospectively collected from 79 patients (11 men, 68 women) with a mean age of 69 years (55 to 86) with fractures of the proximal humerus in order to determine if current guidelines on the measurement of the
Low bone mass and osteopenia have been described in the axial and peripheral skeleton of patients with adolescent idiopathic scoliosis (AIS). Recently, many studies have shown that gene polymorphism is related to osteoporosis. However, no studies have linked the association between IL6 gene polymorphism and bone mass in AIS. This study examined the association between bone mass and IL6 gene polymorphism in 198 girls with AIS. The polymorphisms of IL6-597 G→A, IL6-572 G→C and IL6-174 G→A and the
Transient osteoporosis of the hip is a disorder characterised by pain, and associated with temporary osteopaenia. Although osteopaenia is the essence of the condition, data do not exist about the local bone density of the femoral neck if no medication is administered. We describe three patients who were treated with limitation of weight-bearing only. Repeated
There is limited literature available looking into circumstances surrounding the development of stress fracture of the medial and lateral malleoli after ankle replacement. We present the preliminary results of a prospective study examining the effect of ankle replacement upon local
Aims. The distal radius is a major site of osteoporotic bone loss resulting in a high risk of fragility fracture. This study evaluated the capability of a cortical index (CI) at the distal radius to predict the local
Aims. Assessment of
To analyze the effect of tooth extraction site preservation on
Introduction: Osteoporosis is one of the major diseases worldwide, affecting millions of elderly people, with severe economical and medical consequences. The most commonly used method for the determination of decreased bone quality is the assessment of
Introduction: There is limited literature available looking into circumstances surrounding the development of stress fracture of the medial and lateral malleoli after ankle replacement. We present the preliminary results of a prospective study examining the effect of ankle replacement upon local
Introduction: There is limited literature looking into the circumstances surrounding the development of stress fractures of the medial and lateral malleoli after ankle replacement. We present the preliminary results of a prospective study examining the effect of total ankle replacement (TAR) upon local
Background. Reduced
Varus deformity is found in 90% of patients with knee OA. Axis deviation of lower extremity influences joint biomechanics and produce alteration in
Femoral stem design affects periprosthetic
Aims. To examine the relationship of sex steroid hormones with osteopenia in a nationally representative sample of men in the USA. Methods. Data on
To ascertain whether patients with Colles’ fracture should be investigated for osteoporosis and the risk of future fractures, we measured the
It is accepted that resurfacing hip replacement
preserves the
Aims. The aim of this study was to compare the pattern of initial fixation and changes in periprosthetic
Femoral stem design affects periprosthetic
The measurement of
Objectives. Several genome-wide association studies (GWAS) of
To prevent bone loss, OPG/RANK/RANKL signalling pathway is a key in keeping the balance between the action of osteoblasts and osteoclasts. Aim of this study is to assess the influence of long-term nicotine exposure on
Introduction. There is no published series described change in
To investigate whether children with fractures have a low
We undertook a randomised prospective follow-up study of changes in peri-prosthetic
To evaluate the effects of 6 and 18 months of abaloparatide (ABL) compared with placebo (PBO) on
Our aim in this prospective study was to compare the
We used dual-energy X-ray absorptiometry (DEXA) to compare the
Introduction:. Significant proximal femoral remodeling occurs after total hip arthroplasty (THA), with regions of bone loss, and regions of hypertrophy. This study compared three implants for changes in femoral
Introduction: This study prospectively measured fifty consecutive patients who had the preoperative diagnosis of osteoarthritis undergoing total knee arthroplasty (TKA) to evaluate the change of the
Purpose of study:. The purpose of the study is to evaluate the changes in peri-prosthetic
The shape of the vertebral bodies from L1 to L4 was assessed from lateral dual-energy x-ray absorptiometry (DXA) images using an active shape model. The output from the model was compared to measurements of areal
The
Total Hip Replacement (THR) is one of the most successful operations in all of medicine, however surgeons just rely on their experience and expertise when choosing between cemented or cementless stem, without having any quantitative guidelines. The aim of this project is to provide clinicians with some tools to support in their decision making. A novel method based on
Cementless implants have gained popularity in modern orthopaedic practice. The type implants and surface characteristics on fixation has been extensively investigated, however there is insufficient data on the effect of the host bone bed status on implant fixation. This study aims to determine if there is a correlation between the fixation strength of cementless press-fit implants and
We investigated the effect of locally administered bisphosphonate on distraction osteogenesis in a rabbit model and evaluated its systemic effect. An osteotomy on the right tibia followed by distraction for four weeks was performed on 47 immature rabbits. They were divided into seven equal groups, with each group receiving a different treatment regime. Saline and three types of dosage of alendronate (low, 0.75 μg/kg; mid, 7.5 μg/kg and high 75 μg/kg) were given by systemic injection in four groups, and saline and two dosages (low and mild) were delivered by local injection to the distraction gap in the remaining three groups. The injections were performed five times weekly during the period of distraction. After nine weeks the animals were killed and image analysis and mechanical testing were performed on the distracted right tibiae and the left tibiae which served as a control group. The local low-dose alendronate group showed a mean increase in
Introduction: Selective COX-2 (Cyclooxygenase-2) inhibitors have been found to impede fracture healing. The effect of selective COX-2 inhibitors on tendon healing in a bone tunnel, however, is unknown. Methods: The authors performed bilateral anterior cruciate ligament reconstructions in 32 rabbits and used peripheral quantitative computed tomography (pQCT) to compare tendon-to-bone healing between tunnel aperture and midtunnel regarding
To achieve desirable outcomes in cementless total knee replacement (TKR), sufficient primary stability is essential. The primary stability inhibits excessive motions at the bone-implant interface, hence providing the necessary condition for osseointegration [1]. Primary stability for cementless TKR is provided by press-fit forces between the bone and implant. The press-fit forces depend on several factors including interference fit, friction between bone and implant surface, and the bone material properties. It is expected that
Fractures of the distal forearm are widely regarded as the result of “fragility”. We have examined the extent to which patients with Colles’ fractures have osteopenia. We measured the
We studied the
Dual-energy X-ray absorptiometry (DEXA) is increasingly used to measure changes in
We investigated prospectively the