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The Bone & Joint Journal
Vol. 106-B, Issue 3 Supple A | Pages 137 - 142
1 Mar 2024
van Veghel MHW van der Koelen RE Hannink G Schreurs BW Rijnen WHC

Aims. The aim of this study was to report the long-term follow-up of cemented short Exeter femoral components when used in primary total hip arthroplasty (THA). Methods. We included all primary 394 THAs with a cemented short Exeter femoral component (≤ 125 mm) used in our tertiary referral centre between October 1993 and December 2021. A total of 83 patients (21%) were male. The median age of the patients at the time of surgery was 42 years (interquartile range (IQR) 30 to 55). The main indication for THA was a childhood hip disease (202; 51%). The median follow-up was 6.7 years (IQR 3.1 to 11.0). Kaplan-Meier survival analyses were performed to determine the rates of survival with femoral revision for any indication, for septic loosening, for fracture of the femoral component and for aseptic loosening as endpoints. The indications for revision were evaluated. Fractures of the femoral component were described in detail. Results. The 20-year rate of survival was 85.4% (95% confidence interval (CI) 73.9 to 92.0) with revision for any indication, 96.2% (95% CI 90.5 to 98.5) with revision for septic loosening and 92.7% (95% CI 78.5 to 97.6) with revision for fracture of the femoral component. No femoral components were revised for aseptic loosening. There were 21 revisions of the femoral component; most (seven) as part of a two-stage management of infection. Fracture of the femoral component occurred in four THAs (1.0%) at 6.6, 11.6, 16.5, and 18.2 years of follow-up, respectively. Three of these were transverse fractures and occurred at the level of the lesser trochanter. In one THA, there was a fracture of the neck of the component. Conclusion. THAs using cemented short Exeter femoral components showed acceptable rates of survival of the femoral component at long-term follow-up, in this young cohort of patients. Although fracture is a rare complication of these components, surgeons should be aware of their incidence and possible risk factors. Cite this article: Bone Joint J 2024;106-B(3 Supple A):137–142


Bone & Joint Open
Vol. 3, Issue 6 | Pages 470 - 474
7 Jun 2022
Baek J Lee SC Ryu S Kim J Nam CH

Aims. The purpose of this study was to compare the clinical outcomes, mortalities, implant survival rates, and complications of total knee arthroplasty (TKA) in patients with or without hepatitis B virus (HBV) infection over at least ten years of follow-up. Methods. From January 2008 to December 2010, 266 TKAs were performed in 169 patients with HBV (HBV group). A total of 169 propensity score–matched patients without HBV were chosen for the control group in a one-to-one ratio. Then, the clinical outcomes, mortalities, implant survival rates, and complications of TKA in the two groups were compared. The mean follow-up periods were 11.7 years (10.5 to 13.4) in the HBV group and 11.8 years (11.5 to 12.4) in the control group. Results. The mean Knee Society scores in the HBV and control groups improved from 37.1 (SD 5.6) and 38.4 (SD 5.4) points preoperatively to 78.1 (SD 10.8) and 81.7 (SD 10.2) points at final follow-up (p = 0.314), while the mean function scores in the HBV and control groups improved from 36.2 and 37.3 points preoperatively to 77.8 and 83.2 points at final follow-up (p = 0.137). Nine knees in the HBV group required revision surgery, including seven due to septic loosening and two due to aseptic loosening. Four knees in the control group required revision surgery, including three due to septic loosening and one due to aseptic loosening. Kaplan–Meier survivorship analysis with the revision of either component as an endpoint in the HBV and control groups estimated 96.6% and 98.5% chances of survival for ten years, respectively (p = 0.160). Conclusion. TKA in patients with HBV infection resulted in good clinical outcomes and survivorship. However, there was a higher revision rate over a minimum ten-year follow-up period compared to TKA in patients without HBV infection. Cite this article: Bone Jt Open 2022;3(6):470–474


The Journal of Bone & Joint Surgery British Volume
Vol. 93-B, Issue 9 | Pages 1201 - 1209
1 Sep 2011
Peng K Hsu W Shih H Hsieh C Huang T Hsu RW Chang P

In this study of 41 patients, we used proteomic, Western blot and immunohistochemical analyses to show that several reactive oxygen species scavenging enzymes are expressed differentially in patients with primary osteoarthritis and those with non-loosening and aseptic loosening after total hip replacement (THR). The patients were grouped as A (n = 16, primary THR), B (n = 10, fixed THR but requiring revision for polyethylene wear) and C (n = 15, requiring revision due to aseptic loosening) to verify the involvement of the identified targets in aseptic loosening. When compared with Groups A and B, Group C patients exhibited significant up-regulation of transthyretin and superoxide dismutase 3, but down-regulation of glutathione peroxidase 2 in their hip synovial fluids. Also, higher levels of superoxide dismutase 2 and peroxiredoxin 2, but not superoxide dismutase 1, catalase and glutathione perioxidase 1, were consistently detected in the hip capsules of Group C patients.

We propose that dysregulated reactive oxygen species-related enzymes may play an important role in the pathogenesis and progression of aseptic loosening after THR.


The Bone & Joint Journal
Vol. 104-B, Issue 4 | Pages 472 - 478
1 Apr 2022
Maccario C Paoli T Romano F D’Ambrosi R Indino C Federico UG

Aims. This study reports updates the previously published two-year clinical, functional, and radiological results of a group of patients who underwent transfibular total ankle arthroplasty (TAA), with follow-up extended to a minimum of five years. Methods. We prospectively evaluated 89 patients who underwent transfibular TAA for end-stage osteoarthritis. Patients’ clinical and radiological examinations were collected pre- and postoperatively at six months and then annually for up to five years of follow-up. Three patients were lost at the final follow-up with a total of 86 patients at the final follow-up. Results. A total of 86 patients were evaluated at a mean follow-up of 65.4 months (60 to 90). At five-year follow-up, statistically significant improvements (p < 0.001) were found in the mean American Orthopaedic Foot & Ankle Society Ankle Hindfoot Score (from 33.8 (SD 14.3) to 86.1 (SD 8.8)), visual analogue scale for pain (from 8.5 (SD 1.7) to 1.5 (SD 1.2)), Short Form-12 Physical and Mental Component Scores (from 29.9 (SD 6.7) and 43.3 (SD 8.6) to 47.3 (SD 7.5) and 52.2 (SD 8.0), respectively), and mean ankle dorsiflexion and plantarflexion (from 6.2° (SD 5.5°) and 9.6° (SD 5.8°) to 23.9° (SD 7.7°) and 16.9° (SD 7.2°), respectively). Radiologically, the implants maintained neutral alignment without subsidence. Tibial or talar radiolucency was found in eight patients, but none of these patients was symptomatic. At five-year follow up, 97.7% of implants (95% confidence interval 91.2 to 99.4) were free from revision or removal with 84 implants at risk. We recorded two cases (2.3%) of failure for septic loosening. Conclusion. Transfibular TAA is safe and effective with a high survival rate at mid-term follow-up and satisfactory clinical and radiological results. Further studies are required to determine the long-term performance of these implants. Cite this article: Bone Joint J 2022;104-B(4):472–478


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_12 | Pages 17 - 17
23 Jun 2023
Schreurs BW van Veghel MH van der Koelen RE Hannink G Rijnen WH
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Although data on uncemented short stems are available, studies on cemented short-stemmed THAs are limited. These cemented short stems may have inferior long-term outcomes and higher femoral component fracture rates. Hence, we examined the long-term follow-up of cemented short Exeter stems used in primary THA. Within the Exeter stem range, 7 stems have a stem length of 125 mm or less. These stems are often used in small patients, in young patients with a narrow femoral canal or patients with anatomical abnormalities. Based on our local database, we included 394 consecutive cemented stems used in primary THA (n=333 patients) with a stem length ≤125 mm implanted in our tertiary referral center between 1993 and December 2021. We used the Dutch Arthroplasty Registry (LROI) to complete and cross-check the data. Kaplan-Meier survival analyses were performed to determine 20-year survival rates with stem revision for any reason, for septic loosening, for aseptic loosening and for femoral component fracture as endpoints. The proportion of male patients was 21% (n=83). Median age at surgery was 42 years (interquartile range: 30–55). The main indication for primary THA was childhood hip diseases (51%). The 20-year stem survival rate of the short stem was 85.4% (95% CI: 73.9–92.0) for revision for any reason and 96.2% (95%CI: 90.5–98.5) for revision for septic loosening. No stems were revised for aseptic femoral loosening. However, there were 4 stem fractures at 6.6, 11.6, 16.5 and 18.2 years of follow-up. The stem survival with femoral component fracture as endpoint was 92.7% (CI: 78.5–97.6) at 20 years. Cemented short Exeter stems in primary THA show acceptable survival rates at long-term follow-up. Although femoral component fracture is a rare complication of a cemented short Exeter stem, orthopaedic surgeons should be aware of its incidence and possible risk factors


The Bone & Joint Journal
Vol. 101-B, Issue 12 | Pages 1489 - 1497
1 Dec 2019
Wang J Ma H Chou TA Tsai S Chen C Wu P Chen W

Aims. The aim of this meta-analysis was to compare the outcome of total elbow arthroplasty (TEA) undertaken for rheumatoid arthritis (RA) with TEA performed for post-traumatic conditions with regard to implant failure, functional outcome, and perioperative complications. Materials and Methods. We completed a comprehensive literature search on PubMed, Web of Science, Embase, and the Cochrane Library and conducted a systematic review and meta-analysis. Nine cohort studies investigated the outcome of TEA between RA and post-traumatic conditions. The preferred reporting items for systematic reviews and meta-analysis (Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)) guidelines and Newcastle-Ottawa scale were applied to assess the quality of the included studies. We assessed three major outcome domains: implant failures (including aseptic loosening, septic loosening, bushing wear, axle failure, component disassembly, or component fracture); functional outcomes (including arc of range of movement, Mayo Elbow Performance Score (MEPS), and the Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire), and perioperative complications (including deep infection, intraoperative fracture, postoperative fracture, and ulnar neuropathy). Results. This study included a total of 679 TEAs for RA (n = 482) or post-traumatic conditions (n = 197). After exclusion, all of the TEAs included in this meta-analysis were cemented with linked components. Our analysis demonstrated that the RA group was associated with a higher risk of septic loosening after TEA (odds ratio (OR) 3.96, 95% confidence interval (CI) 1.11 to 14.12), while there was an increased risk of bushing wear, axle failure, component disassembly, or component fracture in the post-traumatic group (OR 4.72, 95% CI 2.37 to 9.35). A higher MEPS (standardized mean difference 0.634, 95% CI 0.379 to 0.890) was found in the RA group. There were no significant differences in arc of range of movement, DASH questionnaire, and risk of aseptic loosening, deep infection, perioperative fracture, or ulnar neuropathy. Conclusion. The aetiology of TEA surgery appears to have an impact on the outcome in terms of specific modes of implant failures. RA patients might have a better functional outcome after TEA surgery. Cite this article: Bone Joint J 2019;101-B:1489–1497


Bone & Joint Open
Vol. 4, Issue 2 | Pages 79 - 86
10 Feb 2023
McLaughlin JR Johnson MA Lee KR

Aims. The purpose of this study is to report our updated results at a minimum follow-up of 30 years using a first generation uncemented tapered femoral component in primary total hip arthroplasty (THA). Methods. The original cohort consisted of 145 consecutive THAs performed by a single surgeon in 138 patients. A total of 37 patients (40 hips) survived a minimum of 30 years, and are the focus of this review. The femoral component used in all cases was a first-generation Taperloc with a non-modular 28 mm femoral head. Clinical follow-up at a minimum of 30 years was obtained on every living patient. Radiological follow-up at 30 years was obtained on all but four. Results. Seven femoral components (18%) required revision, and none for septic loosening. Four well fixed stems were removed during acetabular revision and three were revised for late infection. One femoral component (3%) was loose by radiological criteria. The mean Harris Hip Score improved from 47 points (SD 4.62) preoperatively to 83 points (SD 9.27) at final follow-up. With revision for any reason as the endpoint, survival of the femoral component was 80% (95% confidence interval (CI) 61% to 90%) at 32 years. With revision for aseptic loosing femoral component, survival was 99% (95% CI 93% to 99%). Conclusion. With regards to aseptic loosening, the Taperloc femoral component provides excellent fixation at a mean follow-up of 32 years. Cite this article: Bone Jt Open 2023;4(2):79–86


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_3 | Pages 52 - 52
23 Feb 2023
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THA in patients with acetabular bone defects is associated with a high risk of dislocation. Dual mobility (DM) cups are known to prevent and treat chronic instability. The aim of this study was to evaluate the dislocation rate and survival of jumbo DM cups. This was a retrospective, continuous, multicenter study of all the cases of jumbo DM cup implantation between 2010 and 2017 in patients with acetabular bone loss (Paprosky 2A: 46%, 2B: 32%, 2C: 15% and 3A: 6%). The indications for implantation were revisions for aseptic loosening of the cup (n=45), aseptic loosening of the femoral stem (n=3), bipolar loosening (n=11), septic loosening (n=10), periprosthetic fracture (n=5), chronic dislocation (n=4), intraprosthetic dislocation (n=2), cup impingement (n=1), primary posttraumatic arthroplasty (n=8), and acetabular dysplasia (n=4). The jumbo cups used were COPTOS TH (SERF), which combines press-fit fixation with supplemental fixation (acetabular hook, two superior flanges with one to four screws, two acetabular pegs). A bone graft was added in 74 cases (80%). The clinical assessment consisted of the Harris hip score. The primary endpoint was surgical revision for aseptic acetabular loosening or the occurrence of a dislocation episode. In all, 93 patients were reviewed at a mean follow-up of 5.3 ± 2.3 years [0, 10]. As of the last follow-up, the acetabular cup had been changed in five cases: three due to aseptic loosening (3.2%) and two due to infection (2.1%). The survivorship free of aseptic loosening was 96.8%. Three patients (3%) suffered a dislocation. At the last follow-up visit, the mean HSS scores were 72.15, (p < 0.05). Use of a jumbo DM cup in cases of acetabular bone defects leads to satisfactory medium-term results with low dislocation and loosening rates


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_12 | Pages 10 - 10
1 Dec 2022
Rizkallah M Ferguson P Basile G Werier JM Kim P Wilson D Turcotte R
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The reconstruction of peri-acetabular defects after severe bone loss or pelvic resection for tumor is among the most challenging surgical intervention. The Lumic® prosthesis (Implantcast, Buxtehude, Germany) was first introduced in 2008 in an effort to reduce the mechanical complications encountered with the classic peri-acetabular reconstruction techniques and to improve functional outcomes. Few have evaluated the results associated with the use of this recent implant. A retrospective study from five Orthopedic Oncology Canadian centers was conducted. Every patient in whom a Lumic® endoprosthesis was used for reconstruction after peri-acetabular resection or severe bone loss with a minimal follow-up of three months was included. The charts were reviewed and data concerning patients’ demographics, peri-operative characteristics and post-operative complications was collected. Surgical and functional outcomes were also assessed. Sixteen patients, 11 males and five females, were included and were followed for 28 months [3 – 60]. Mean age was 55 [17–86], and mean BMI reached 28 [19.6 – 44]. Twelve patients (75%) had a Lumic® after a resection of a primary sarcoma, two following pelvic metastasis, one for a benign tumor and one after a comminuted acetabular fracture with bone loss. Twelve patients (75%) had their surgery performed in one stage whereas four had a planned two-stage procedure. Mean surgical time was 555 minutes [173-1230] and blood loss averaged 2100 mL [500-5000]. MSTS score mean was 60.3 preoperatively [37.1 – 97] and 54.3 postoperatively [17.1-88.6]. Five patients (31.3%) had a cemented Lumic® stem. All patients got the dual mobility bearing, and 10 patients (62.5%) had the largest acetabular cup implanted (60 mm). In seven of these 10 patients the silver coated implant was used to minimize risk of infection. Five patients (31.3%) underwent capsular reconstruction using a synthetic fabric aiming to reduce the dislocation risk. Five patients had per-operative complications (31.3%), four were minor and one was serious (comminuted iliac bone fracture requiring internal fixation). Four patients dislocated within a month post-operatively and one additional patient sustained a dislocation one year post-operatively. Eight patients (50%) had a post-operative surgical site infection. All four patients who had a two-stage surgery had an infection. Ten patients (62.5%) needed a reoperation (two for fabric insertion, five for wash-outs, and three for implant exchange/removal). One patient (6.3%) had a septic loosening three years after surgery. At the time of data collection, 13 patients (81.3%) were alive with nine free of disease. Silver coating was not found to reduce infection risk (p=0.2) and capsuloplasty did not prevent dislocation (p=1). These results are comparable to the sparse data published. Lumic® endoprosthesis is therefore shown to provide good functional outcomes and low rates of loosening on short to medium term follow-up. Infection and dislocation are common complications but we were unable to show benefits of capsuloplasty and of the use of silver coated implants. Larger series and longer follow-ups are needed


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_13 | Pages 96 - 96
1 Dec 2022
Rizkallah M Ferguson P Basile G Werier JM Kim P Wilson D Turcotte R
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The reconstruction of peri-acetabular defects after severe bone loss or pelvic resection for tumor is among the most challenging surgical intervention. The Lumic® prosthesis (Implantcast, Buxtehude, Germany) was first introduced in 2008 in an effort to reduce the mechanical complications encountered with the classic peri-acetabular reconstruction techniques and to improve functional outcomes. Few have evaluated the results associated with the use of this recent implant. A retrospective study from five Orthopedic Oncology Canadian centers was conducted. Every patient in whom a Lumic® endoprosthesis was used for reconstruction after peri-acetabular resection or severe bone loss with a minimal follow-up of three months was included. The charts were reviewed and data concerning patients’ demographics, peri-operative characteristics and post-operative complications was collected. Surgical and functional outcomes were also assessed. Sixteen patients, 11 males and five females, were included and were followed for 28 months [3 – 60]. Mean age was 55 [17-86], and mean BMI reached 28 [19.6 – 44]. Twelve patients (75%) had a Lumic® after a resection of a primary sarcoma, two following pelvic metastasis, one for a benign tumor and one after a comminuted acetabular fracture with bone loss. Twelve patients (75%) had their surgery performed in one stage whereas four had a planned two-stage procedure. Mean surgical time was 555 minutes [173-1230] and blood loss averaged 2100 mL [500-5000]. MSTS score mean was 60.3 preoperatively [37.1 – 97] and 54.3 postoperatively [17.1-88.6]. Five patients (31.3%) had a cemented Lumic® stem. All patients got the dual mobility bearing, and 10 patients (62.5%) had the largest acetabular cup implanted (60 mm). In seven of these 10 patients the silver coated implant was used to minimize risk of infection. Five patients (31.3%) underwent capsular reconstruction using a synthetic fabric aiming to reduce the dislocation risk. Five patients had per-operative complications (31.3%), four were minor and one was serious (comminuted iliac bone fracture requiring internal fixation). Four patients dislocated within a month post-operatively and one additional patient sustained a dislocation one year post-operatively. Eight patients (50%) had a post-operative surgical site infection. All four patients who had a two-stage surgery had an infection. Ten patients (62.5%) needed a reoperation (two for fabric insertion, five for wash-outs, and three for implant exchange/removal). One patient (6.3%) had a septic loosening three years after surgery. At the time of data collection, 13 patients (81.3%) were alive with nine free of disease. Silver coating was not found to reduce infection risk (p=0.2) and capsuloplasty did not prevent dislocation (p=1). These results are comparable to the sparse data published. Lumic® endoprosthesis is therefore shown to provide good functional outcomes and low rates of loosening on short to medium term follow-up. Infection and dislocation are common complications but we were unable to show benefits of capsuloplasty and of the use of silver coated implants. Larger series and longer follow-ups are needed


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 360 - 360
1 Jul 2011
Ovrenovits M Pakos E Vartholomatos G Mitsionis G
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The aim of the study to analyze the circulating white blood cells including the intensity expression of surface receptors and cytoplasmic molecules in patients underwent total hip replacement, with either aseptic or septic loosening of hip prostheses in order to identify cell-surface and cytoplasmic markers that could be indicative of early loosening. Flow cytometry was performed in whole peripheral blood samples of 20 patients with loosening (10 septic and 10 aseptic). Ten healthy individuals served a control group. The CD62L, CD18, CD11a, CD11b and CD11c expressions were evaluated. The mean fluorescence intensity (MFI) of CD 18 was decreased on all leukocytes subsets compared to control group. For patients with aseptic loosening we demonstrated an increase of MFI for CD11b in granulocytes and for CD11c in monocytes and granulocytes compared to control group. In patients with septic loosening an increase of MFI for CD 11c was observed in monocytes compared to control group. The comparison between aseptic and septic loosening showed a statistically significant lower CD18 MFI value in granulocytes for aseptic loosening. A trend towards lower MFI values of CD 62L in lymphocytes and granulocytes were observed in aseptic but not in septic loosening patients compared to control group. The present study is the first study in published literature to demonstrate cell surface and cytoplasmic markers in peripheral blood indicative of loosening of THAs by means of flow cytometry


The Bone & Joint Journal
Vol. 101-B, Issue 8 | Pages 910 - 914
1 Aug 2019
Kiran M Donnelly TD Armstrong C Kapoor B Kumar G Peter V

Aims. Prosthetic joint infection (PJI) and aseptic loosening in total hip arthroplasty (THA) can present with pain and osteolysis. The Musculoskeletal Infection Society (MSIS) has provided criteria for the diagnosis of PJI. The aim of our study was to analyze the utility of F18-fluorodeoxyglucose (FDG) positron emission tomography (PET) CT scan in the preoperative diagnosis of septic loosening in THA, based on the current MSIS definition of prosthetic joint infection. Patients and Methods. A total of 130 painful unilateral cemented THAs with a mean follow-up of 5.17 years (. sd. 1.12) were included in this prospective study. The mean patient age was 67.5 years (. sd. 4.85). Preoperative evaluation with inflammatory markers, aspiration, and an F18 FDG PET scan were performed. Diagnostic utility tests were also performed, based on the MSIS criteria for PJI and three samples positive on culture alone. Results. The mean erythrocyte sedimentation rate, C-reactive protein, and white cell count were 47.83 mm/hr, 25.21 mg/l, and 11.05 × 10. 9. /l, respectively. The sensitivity, specificity, accuracy, negative predictive value, and false-positive rate of FDG PET compared with MSIS criteria were 94.87%, 38.46 %, 56.38%, 94.59 %, and 60.21%, respectively. The false-positive rate of FDG PET compared with culture alone was 77.4%. Conclusion. FDG PET has a definitive role in the preoperative evaluation of suspected PJI. This the first study to evaluate its utility based on MSIS criteria and compare it with microbiology results alone. However, FDG PET has a high false-positive rate. Therefore, we suggest that F18 FDG PET is useful in confirming the absence of infection, but if positive, may not be confirmatory of PJI. Cite this article: Bone Joint J 2019;101-B:910–914


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 331 - 331
1 Jul 2011
Bjerkan G Bergh K Witso E
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Aims: The symptoms of aseptic and septic prosthetic joint loosening may be similar, and identification of low-grade prosthetic infection based only on clinical history and physical examination has a reported low sensitivity. In a prospective study we explored to what extent a thorough examination of the patient’s history of sickness and a standardized preoperative clinical examination could help the surgeon to identify cases of septic loosening. Methods: We included 54 patients undergoing revision surgery due to loosening of a total hip or knee prosthesis. Preoperatively a standardized form which included data regarding the patient’s history of sickness was obtained and a physical examination was performed. Postoperatively a final diagnose was made based on microbiological testing, which in addition to routine culture, included sonication of the prosthesis and nucleic acid based diagnostics (PCR). Data from the preoperative examination was evaluated in relation to the final diagnose (chi-square test and Student’s t-test), and the sensitivity and specificity for diagnosing a septic loosening was calculated for each preoperative finding. Results: According to the final diagnose, 21 patients had a septic loosening and 33 patients had an aseptic loosening. In the septic group and aseptic group the following anamnestic data was registered: Pain during rest: 16/21 vs. 7/33 (p < 0.001). Prior history of soft tissue debridement: 11/21 vs. 4/33 (p = 0.001). Prior prosthetic revision surgery: 13/21 vs. 8/33 (p = 0.006). Time from index operation to revision: 45 (5 – 144) moths vs. 159 (22–390) moths, (p = 0.02). Time from index operation to debut of prosthetic assosiated dyscomfort: 10 (0–110) moths vs. 120 (0–240) moths, (p < 0.001). The calculated sensitivity (se) and spesifisity (sp) for the pre-operative findings were: Existence of prosthetic related pain during rest: 79% se, 79% sp; history of soft tissue revision in the affected joint 52% se, 88% sp; history of prior exchange prosthetic revision in the affected joint 62% se, 76% sp, respectively. Conclusion: We advise a carefully obtained history from every patient presenting with loosening of implanted prosthetic components for identification of a potential low grade infection. In particular, pain during rest has a notable sensitivity and specificity. A prior history of soft tissue revision also strongly indicates a septic prosthetic loosening


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_15 | Pages 25 - 25
1 Mar 2013
Bruni D Iacono F Presti ML Sharma B Raspugli G Marcacci M
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INTRODUCTION. Conventional surgical exposures are usually inadequate for 2-stage revision knee replacement ofinfected implants. Reduced range of motion, extensor mechanism stiffness, peripatellar contracture and soft tissue scarring make patellar eversion difficult and forced eversion places the integrity of the extensor mechanism at risk. On the contrary, a wide exposure is fundamental to allow complete cement spacer removal, soft tissue balancing, management of bone loss and reimplantation without damaging periarticular soft tissues. OBJECTIVES. To compare the long-term clinical, functional and radiographic results and the reinfection rate of the quadriceps snip approach and the tibial tubercle osteotomy in 2-stage revision knee replacement performed for septic loosening of the primary implant. METHODS. In our department, 87 patients had a 2 stage revision knee replacement for septic loosening of the primary implant between 1996 and 2008. In all patients, first stage consisted of primary implant removal, extensive soft tissue debridement and positioning of a static antibiotic loaded cement spacer. The timing for reimplantation was decided basing on negative clinical and laboratory (ESR, CRP) signs and negative Leukoscan results. For reimplantation, a quadriceps snip was used in patients with an intraoperative flexion >90° (Group A) while a tibial tubercle osteotomy (Group B) was used in patients with an intraoperative flexion <90°. RESULTS. At observation point, 4 patients died for reasons unrelated to surgery, leaving 42 patients in Group A and 41 in Group B. We had a total amount of 10 recurrent infections (11%) after reimplantation, 7 patients in Group A and 3 patients in Group B (p<0.005). Patients with a reinfection in Group A were treated with a knee fusion in 4 cases, a rerevision in 2 cases and an amputation above the knee in 1 case, while all those with a reinfection in Group B had a knee fusion. According to HSS score, 11 patients were rated as Excelent/Good in Group A and 9 patients in Group B (p=n.s.). Three patients had a major complication in Group A and 0 patients in Group B (p=0.005). No differences were found between the two groups regarding range of motion and subjective satisfaction. CONCLUSION. Tibial tubercle osteotomy is a safe procedure to obtain a wide exposure in 2-stage revision knee replacement performed for septic loosening of the primary implant and it is effective in reducing reinfection rate without compromising clinical results and range of motion


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_2 | Pages 107 - 107
1 Jan 2016
Kindsfater K Sherman C Bureau C
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Introduction. Revision TKA can be a difficult and complex procedure. Bone quality is commonly compromised and stem fixation is required in many cases to provide stability of the prosthetic construct. However, utilization of diaphyseal engaging stems adds complexity to the case and can present technical challenges to the surgeon. Press fit metaphyseal sleeves can provide stable fixation of the construct without the need for stems and allows for biologic ingrowth of the prosthesis. Metaphyseal sleeves simplify the revision procedure by avoiding the need to prepare the diaphysis for stems, alleviating the need for offset stems and decreasing the risk of intra-operative complications. The ability to obtain biologic fixation in the young patient is also appealing. This study reports on the author's mid-term experience with this novel technique. Methods. Between May 2007 and June 2009 the author performed 17 revisions TKA that utilized press-fit metaphyseal sleeves without stems on either the tibial side of the joint, the femoral side of the joint or both. Twenty six sleeves were implanted altogether (13 tibial, 13 femoral). Patients were limited to touch down weight bearing for 6 weeks post-operatively. The patients were followed prospectively with clinical and radiographic follow-up at routine intervals. Results. Average clinical and radiographic F/U for the cohort was 57 months (range 30 – 77). Fourteen of seventeen patients had a minimum of 4 years F/U. Average age at the time of surgery was 58 years (range 46–72) and average BMI was 32.4. Indications for the index revision included nine knees with aseptic loosening and / or osteolysis, two knees for septic loosening, two knees for instability and 4 knees for pain / stiffness or other causes. ROM at pre-op and latest F/U averaged 2–108 deg and 0–117 deg respectively. Knee Society Scores at pre-op and latest F/U averaged 35 and 86 respectively (range 57–100). Survivorship analysis revealed 25 of 26 sleeves (96%) to still be in situ at latest F/U. One tibial sleeve was revised at 30 months for septic loosening. Radiographic analysis revealed 22 of the remaining 25 sleeves (88%) to be ingrown. Two tibial sleeves and one femoral sleeve exhibit stable fibrous fixation and are asymptomatic. Conclusions. Press-fit metaphyseal sleeves utilized without stems appear to provide excellent stability of the revision TKA construct at mid-term F/U. Biologic fixation appears to be present in the majority of cases. This ability to obtain reliable osseointegration of the revision construct is appealing, especially in the younger revision patient. The sleeves have proven easy to use and there have been no intra-operative complications. This technique appears to provide a simple, but robust alternative when compared to revision TKA with stems in appropriate cases. Further F/U of this cohort is necessary to evaluate long term results


The Journal of Bone & Joint Surgery British Volume
Vol. 91-B, Issue 9 | Pages 1148 - 1153
1 Sep 2009
Schreurs BW Keurentjes JC Gardeniers JWM Verdonschot N Slooff TJJH Veth RPH

We present an update of the clinical and radiological results of 62 consecutive acetabular revisions using impacted morsellised cancellous bone grafts and a cemented acetabular component in 58 patients, at a mean follow-up of 22.2 years (20 to 25). The Kaplan-Meier survivorship for the acetabular component with revision for any reason as the endpoint was 75% at 20 years (95% confidence interval (CI) 62 to 88) when 16 hips were at risk. Excluding two revisions for septic loosening at three and six years, the survivorship at 20 years was 79% (95% CI 67 to 93). With further exclusions of one revision of a well-fixed acetabular component after 12 years during a femoral revision and two after 17 years for wear of the acetabular component, the survivorship for aseptic loosening was 87% at 20 years (95% CI 76 to 97). At the final review 14 of the 16 surviving hips had radiographs available. There was one additional case of radiological loosening and four acetabular reconstructions showed progressive radiolucent lines in one or two zones. Acetabular revision using impacted large morsellised bone chips (0.5 cm to 1 cm in diameter) and a cemented acetabular component remains a reliable technique for reconstruction, even when assessed at more than 20 years after surgery


The Journal of Bone & Joint Surgery British Volume
Vol. 90-B, Issue 11 | Pages 1417 - 1421
1 Nov 2008
de Kam DCJ Klarenbeek RLWA Gardeniers JWM Veth RPH Schreurs BW

We evaluated the outcome of 104 consecutive primary cemented Exeter femoral components in 78 patients (34 men, 44 women) under the age of 40 years who underwent total hip replacement between October 1993 and May 2004. The mean age at operation was 31 years (16 to 39). No hip was lost to follow-up, but three patients (four hips) died. None of the deaths were related to the surgery. At a mean follow-up of 6.2 years (2 to 13), three femoral components had been revised for septic loosening. Using Kaplan-Meier survival analysis, the seven-year survival of the component with revision for any reason as the endpoint was 95.8% (95% confidence interval 86.67 to 98.7). The seven-year survival with aseptic femoral loosening as the endpoint was 100% (95% confidence interval 100). The cemented Exeter femoral component in patients under the age of 40 shows promising medium-term results. As it is available in a wide range of sizes and offsets, we could address all types of anatomical variation in this series without the need for custom-made components


The Journal of Bone & Joint Surgery British Volume
Vol. 87-B, Issue 8 | Pages 1073 - 1076
1 Aug 2005
Cross MJ Parish EN

We prospectively reviewed 1000 consecutive patients who underwent a cementless, hydroxyapatite-coated, stemless, total knee replacement over a period of nine years. Regular post-operative clinical follow-up was performed using the Knee Society score. The mean pre-operative score was 96, improving to 182 and 180 at five and ten years, respectively. To date, there have been seven (0.5%) cases which required revision, primarily for septic loosening (four cases), with low rates of other post-operative complications. The cumulative survival at ten years with revision as the end-point, was 99.14% (95% confidence interval 92.5 to 99.8). These results support the use of hydroxyapatite in a cementless total knee replacement since it can give reliable fixation with an excellent clinical and functional outcome


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 575 - 575
1 Oct 2010
Salama A Nicoletti S Stanley D
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At our institution between 1994 and 2003 a total of 36 revision total elbow Arthroplasties were performed in 34 patients. We clinically reviewed 25 patients and reviewed the notes and x-rays of all of them. Of eleven who were not reviewed clinically seven had died from an unrelated cause and four were unable to attend because of illness but we were able to include them as sufficient data were available in the notes. There were 24 female and 12 male, Average age was 67 years and twelve had elbow Arthroplasty in a non-dominant side. The average follow up was 6 years (range 5–13 years). The mean period between the primary and revision surgery was sixty three months (range 3–240 months). The indication for surgery was mainly for aseptic loosening in 15 cases, followed by septic loosening in twelve. All cases of septic loosening had two stage revisions. Other reasons for revision in this series include unstable elbows, implant fracture and peri-prosthetic fractures. Twelve of these revisions had a further revision for a variety of reasons at an average period of twenty eight months. Seven patients had thirteen complications in this series, two radial nerve palsies (one recovered), one distal humeral fracture, five cortical perforations and five triceps weakness. Most of the patients are satisfied with their elbows. The mean Mayo elbow Performance Score was 79 points. We conclude that revision Elbow Arthroplasty is a specialized surgery which is technically demanding, with high risk of complications and high re-revision rate and therefore, should be done in a specialised centres


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 164 - 165
1 Mar 2008
Fravisini M Pellacani A Stagni C Veronesi M Dallari D Giunti A
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Girdlestone’s arthroplasty is often used to treat septic loosening of hip prostheses. Although this operation provides goodresults with regards to pain and loosening, it causes instability and in the hip and limb shortening that force the patient to use walking aids. From 1990 to 1999 we treated ten cases of revisionhip arthroplasty after Girdlestone’s arthroplasty. Girdleston e’sarthroplasty was carried out in all cases due to sepsis in the previousimplant. Preoperatively all patients underwent granulocyte-labeledscintigraphy. For clinical evaluation we used the Merle D’Aubignè score. From 1990 to 1999 we treated ten cases of revisionhip arthroplasty after Girdlestone’s arthroplasty. Girdleston e’sarthroplasty was carried out in all cases due to sepsis in the previousimplant. Preoperatively all patients underwent granulocyte-labeledscintigraphy. For clinical evaluation we used the Merle D’Aubignè score. Girdlestone’s arthroplasty is very effective for treating septic loosening of hip prostheses, but it causes severe walking impediment. Revision surgery restores limb length and walking. Patients that undergo this treatment should be checked for residual sepsis, which may jeopardize the operation. Currently we are experimenting with spacers with antibiotics and our initial results are promising


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 317 - 317
1 May 2009
Cortés S Sancho R Pellejero R Valera M Crusi X
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Introduction: Hip replacement prosthesis infection is a severe complication of ever increasing incidence. Currently there is controversy as to whether prosthetic revision surgery should be carried out in one or two stages and whether cemented or uncemented prostheses should be used. Materials and methods: This is a retrospective study of 17 cases of chronic infections of hip replacements that were revised in one-stage procedures between 1996 and 2005 in our center. Mean follow-up is 3.4 years. We analyzed the functional status of the hips before and after revision using the Merle D’Aubigne scale, x-rays, and supplementary tests for diagnosis and decisions on treatment. Results: The functional score at the end of the follow-up was 16.17 (Merle D’Aubigne scale). The most common pathogen is coagulase-negative staphylococci. Acute phase reactive elements reached normal levels. X-ray control does not show any alterations or signs of loosening. No subsequent revisions have been performed. Conclusions: The diagnosis and treatment of prosthetic revision requires correct preoperative assessment and planning. Differential diagnosis of aseptic versus septic loosening in chronic infections is complex; in some cases it is necessary to wait for definite culture results for a surefire diagnosis. We think that in selected chronic cases of septic loosening of the hip due no non-multi-resistant organisms, one-stage revision using a Wagner osteotomy for diaphyseal cleaning combined with a hydoxyapatite-coated stem makes it possible to achieve good functional results and control infection, decreasing the morbidity and cost of a two-stage revision


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XLIII | Pages 40 - 40
1 Sep 2012
Sunderamoorthy D Gudipati S Harris N
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Numerous techniques are used for the fusion of failed TAR. We wish to report our results of the revision of failed TAR to fusion. Between July 2005 and February 2011 the senior author had performed 20 arthrodeses in 19 patients (13 male and 6 female) who had failed total ankle arthroplasty (TAR). Their mean age was 63.5 years. All of them had the AES total ankle replacement. (Biomet UK). The mean period from the original TAR to fusion was 51 months (6 to72). The indication for revision of TAR to fusion was septic loosening in 4 patients and osteolysis and or aseptic loosening in 16 cases. Three types of fusion techniques were used. The mean follow-up was 15 months. All 3 tibiotalar arthrodeses with screws alone fused successfully. Of the 13 patients where the fusion was augmented with an Ilizarov frame, 4 were done for septic loosening. There were 2 non unions of which one was stable without pain and the other required a further revision fusion with a frame and subsequently fused. Of the 9 patients who had a fusion with a frame for osteolysis and or aseptic loosening, there was one non union which was revised to a tibiotalocalacaneal fusion with a hind foot nail. The nail fractured at the level of the posterior oblique screw hole. The patient subsequently developed a relatively pain free non-union of the tibiotalar joint and not required further surgical intervention. The remaining 8 ankles fused at a mean of 5 months. The average time of frame removal was 17 weeks. There was four pin-site infection all of which settled with oral antibiotics. 5 patients had tibiotalocalacaneal fusion with a hind foot nail. The indication for the hind foot nail was significant osteolysis and loss of talar bone stock. The average shortening as a result of the fusion for the failed TAR was 1.5cms. Our results were comparable to the previous reports of arthrodesis for failed total ankle replacement. We recommend the use of tibiotalocalcaneal fusion with a hind foot nail in the presence of severe osteolysis or accompanying subtalar arthritis. In the presence of good bone stock an ankle fusion supplemented with a circular frame gives a good predictable outcome


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 311 - 311
1 Mar 2004
Schreurs B Bolder S Gardeniers J Buma P Slooff T
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Aims: To test the outcome of acetabular revisons with impacted morsellized bone grafts and a cemented cup at a minimum follow-up of 15 years. Methods: Between 1979–1986 62 acetabular revisions (58 patients) were performed with impacted bone grafts and a cemented cup. Two cases (2 hips) were lost to FU. The average age at operation was 59.1 years. The indication was aseptic in 56 and septic loosening in 4 hips. Defects were AAOS-classiþed as ñcavitaryñ in 37 and ñcombinedñ 23 cases. Femoral-head allografts were used. Acetabular re-revisions were determined, the HHS obtained and radiographs analyzed. Results: Nineteen cases (20 hips) died within þfteen years after the operation, none had a re-revision. Eleven acetabular re-revisions were performed: 2 septic loosenings (3 and 6 years p.o.), 7 aseptic loosenings (6, 9, 11, 12, 13, 14, 14 year p.o.) and two for cup wear (12 and 17 yrs p.o.). The average HHS at follow-up was 86 (50–100). There were no additional radiographic failures. Using Kaplan-Meier analysis the survival with endpoint revision for any reason was 79% at 15 years and 71% at 20 years; for aseptic loosening of the cup 84% at 15 years and 84% at 20 years. Conclusions: This technique is attractive to reconstruct acetabular bone stock loss


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_17 | Pages 50 - 50
1 Dec 2018
Huguet S Gómez L Bernaus M Matamala A Cuchi E Font-Vizcarra L
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Aim. In two-stage replacements for septic loosening, some studies have suggested that associate bacterial colonization of spacers had a worse result in relation to the control of the infection and a higher rate of complications after the implantation of the definitive prosthesis. The aim of our study was to determine the reoperation rate of patients undergoing two-stage revision surgery according to the results of spacer sonication. Method. A retrospective observational study was conducted in which 56 hip or knee spacers implanted at our center from 2010 to 2017 were analysed. Patients were grouped into three categories:. Patients with positive spacer sonication fluid culture, with or without positive cultures from the rest of the samples. Patients with negative spacer sonication culture and negative second-stage intraoperative cultures. Patients with negative spacer sonication culture but positive cultures of the rest of intraoperative samples. Results. Of the 56 patients analysed, 11 were included in group A, 32 in group B and 13 in group C. The reoperation rate was 36%, 34% and 54% respectively. Reoperation rate due to infection was 9%, 25% and 46% respectively. In only two cases (both in group C), the reoperation was caused by infection by a previously isolated microorganism. Spacers were colonized in all cases by low virulence microorganisms (coagulase negative staphylococci, P. acnes or Candida). Within group A, six patients also had other positive cultures. Conclusions. In our study, bacterial colonization of the spacer is not associated with a higher rate of reoperations in the short-medium term. The group of patients with positive cultures in the second stage surgery was the one with the highest rate of reoperations


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 330 - 330
1 Jul 2011
Cicero G Bellomo F Artiaco S Boggio F Buttafarro E
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Introduction: In case of massive bone defect, femoral stem revision may cause significant problems to the orthopaedic surgeons. The periprosthetic infection introduces a further element of complication which often leads to complex surgical strategies. The aim of this study was to assess the preliminary results of femoral revision with modular resection femoral stems in a selected group of patients with infected total hip arthroplasty and extensive bone defect. Materials and Methods: The study group included five patients (three women – two men) with an average age of 72 years (range 62–81 years). From 2006 to 2008 the patients underwent a prosthetic femoral revision with resection modular stems to treat a septic loosened primary hip prosthesis (one case) or revision hip prosthesis (four cases). The bacteria responsible for the infection were MRSE in three cases, MSSE and Str. Agalactie in one case, Proteus Mirabilis in one case. Three patients were treated in election for septic loosening of hip implant and two were admitted in our Department as emergency for a periproshtetic femoral fracture (Duncan type B3). In all the patients the femoral bone defect was grade III-B according to Paprosky classification of femoral bone deficiency. One patient with periproshtetic femoral fracture underwent a one-stage prosthetic revision and four patients sustained a two-stage prosthetic revision. In one patient a local flap was performed and Vaacum Assisted Therapy was applied in order to treat an associated loss of substance. The patients underwent periodical clinical controls in which the result has been evaluated by means of Merle-d’Aubigné hip score. Results: The follow-up period ranged from 10 to 28 months. We observed one case of recurrence of infection in the patient treated with a one-stage revision. At present, we did not observe signs of infection in the remaining four patients who underwent a two-stage revision. As for functional result, four patients walked with supports and one without them. No patient referred moderate or severe residual pain. Discussion: The preservation of bone stock is one of the most important goals in prosthetic revision procedures. In some circumstances the amount of femoral bone loss can be so wide to prevent the application of conventional or modular uncemented femoral stems. In these selected cases cemented modular resection femoral stems may represent the only available option for femoral reconstruction. In our clinical experience this solution offered altogether successful outcomes. In our opinion two-stage revision is the preferable surgical choice


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 137 - 137
1 Apr 2005
Havet E Berthelet J Gabrion A Mertl P de Lestang M
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Purpose: We report a series of 78 total hip arthroplasty revisions using a locked femoral stem, Ultime. Material and methods: These patients presented aseptic loosening (88%) and septic loosening (12%). Fracture was associated in 17%. The preoperative Postel Merle d’Aubligné (PMA) score was 10.2 points. Using the Vives-SOFCOT classification, 29% of the loosenings were stage I, 37% stage II, 24% stage III, and 10% stage IV. All fractures were associated with lossening. We used a femoral window in 57% and trochanterotomy in 14 cases. The first eight patients in this series had an allograft (impacted piecemeal). Most of the patients resumed weight bearing the first week. The PMA score was used to assess outcome. AP and lateral views were used to evaluate stem-bone contact and cortical thickness at three levels. Results: Early complications were phlebitis (n=1) and superficial haematoma (n=5). Late complications were dislocation (n=6), stem fracture (n=2), deep infection (n=3). At last follow-up, 81% of the aseptic loosenings, 77% of the septic loosenings, and 70% of the fractures on stem had a good or excellent PMA score with a mean gain of 4, 5, and 1 points respectively. Bone reconstruction showed an increase in internal cortical (2 to 4.4 mm) and stem-bone contact increased in the lower two-thirds of the stem. Allografts did not improve results. Furthermore, 28% of the patients had hip pain which could not be related to clinical findings or implant characteristics. Half of the patients were reoperated. Conclusion: In this series, functional improvement was similar to that in published series. The femoral window facilitated the procedure and decreased intraoperative complications. The Ultime prosthesis met the objectives set by the manufacturer, i.e. primary stability and bone reconstruction authorising subsequent revision


The Journal of Bone & Joint Surgery British Volume
Vol. 88-B, Issue 3 | Pages 310 - 314
1 Mar 2006
Sexton SA Stossel CA Haddad FS

The Kent hip is a distally-locked femoral stem which was developed to address severe proximal bone loss, severe bony deformity and peri-prosthetic fracture. We reviewed the results of 145 consecutive Kent hips implanted into 141 patients between 1987 and 2000. The indications for implantation were aseptic loosening (75 hips), septic loosening (two), peri-prosthetic and prosthetic fracture (37), severe bony deformity (24), and fracture through a proximal femoral metastasis (seven). The median time to full weight-bearing after surgery was two days and the mean length of follow-up was 5.1 years (2 to 15). Further revisions were required for 13 femoral stems. With removal of the stem for any reason as an end-point, the cumulative survival at five, ten and 15 years was 93%, 89% and 77%, respectively. In patients aged ≥ 70 years, the cumulative survival at 15 years was 92%, compared with 68% in those aged < 70 years. Because of these findings, we recommend the use of interlocking stems in patients aged ≥ 70 years, particularly in those with a peri-prosthetic fracture, for whom alternative methods are limited. Outcome scores and survival data, compared with other systems, indicate that the Kent hip should be used with caution in younger patients


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 138 - 138
1 Apr 2005
Synave J Rosset P Burdin P Favard L
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Purpose: The aim of this work was to assess retrospectively osteofixation and survival of a long custom-made femoral stem with complete hydroxyapatite coating and without locking for replacement of the femoral implant. Material and methods: From 1990 to 1999, 89 stems were implanted for revision total hip arthroplasty. Seventy-five hips were reviewed at one to ten years (mean four years). Radiographic analysis searched for bone damage, osteofixation and implant migration. All measures were taken on the AP views postoperatively and at last follow-up. Results: Revision was performed for aseptic loosening in 75%, for septic loosening in 12%, for fracture in 11% and for instability in 2%. Destruction was SOFCOT stage I in 36%, stage II in 44%, stage III in 17% and could not be assessed in 3%. The femorotomy approach was used in 60% and trochanterotomy in 32% and endofemoral assess in 8%. There were 18% intraoperative fractures, 4.8% postoperative infections and 2.4% dislocations. At last follow-up, the Postel Merle d’Aubigné score was 15.3 and the Harris Hip Score was 77.9. Thigh pain was present in 4%. Bone fixation was considered good in 48%, partial but better than 50% contact in 36% and could not be interpreted in 16%. Complete metaphyseal reconstruction was present in 8%. A piecemeal allograft was used in 89%. Between the postoperative and last follow-up films, 16% of the stems descended a mean 11 mm. Five percent of the stems were removed for infection and one (1.3%) for non-fixation. At five years, 95% of the stems was still in place and 80% at ten years, including removals for infection. All revisions for septic loosening had comparable clinical and radiological results in this series and did not develop secondary infection. Discussion: These results demonstrate the usefulness of the uncemented stems for replacement compared with cemented stems which have a 10% revision rate at five years (SOFCOT 1999). The complete hydroxyapatite coating improves distal fixation of the stem in a healthy zone without compromising secondary proximal fixation and authorising spontaneous metaphyseal bone reconstructions. This may explain the low rate of painful thighs. Modularity and locking could improve the primary fixation and limit descent


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_I | Pages 50 - 50
1 Jan 2004
Lassoued AB Asencio G Bertin R Megy B Kouyoumdjian P Hacini S
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Purpose: The purpose of this work was to assess the quality of the bone reconstruction in contact with the long hydroxyapatite-coated locked femoral stem used in a consecutive series of patients undergoing revision total hip arthroplasty (RTHA). Material and methods: This series of 20 patients underwent RTHA for aseptic loosening (n=15) or septic loosening (n=5) of an AURA prosthesis. Mean age was 70.5 years. Mean time between insertion of the first stem and revision was 11 years for the aseptic patients and 2.6 years for the septic patients. Bony lesions of the femur were assessed with the SOFCOT classification: grade I=5, grade II=4, grade III=4, and grade IV=1. A transfemoral approach with a floating femoral segment was used in 14 patients and an endofemoral approach in six. The septic loosenings were reconstructed in two operative times in four patients and in one operation in one patient. An AURA reconstruction stem was used in 15 cases and a revision stem in five. A complementary cancellous bone graft with the endofemoral approach was used in six patients. Results: Two patients died. All others were reviewed at a mean follow-up of 26 months (range 12–46 months) for clinical and radiographic assessment (five patients also had a supplementary scan at more than three years follow-up). We had three dislocations at 15 days with no recurrence and one case of sepsis at three months which cured after wash out and adapted antibiotics. All the femoral segments healed starting on the tenth week. The PMA score improved from 9.1 to 15.66 and the Harris score from 43.5 to 85.5. At last follow-up, all femoral lesions had moved to a lower SOFCOT score. There was a tight contact between the AURA stem and the femur on the last follow-up scan which showed an increase in the cortical index from 1 to 8 cm from the metaphyseal spine of the stem. None of the patients experienced secondary unlocking or required revision for a shorter stem. Discussion: Revision after femoral failure with bone destruction using a non-cemented hydroxyapatite-coated stem allows immediate prosthetic mechanical stability and intimate bone reconstruction in the metaphyseal diaphyseal region. This reconstruction is real even if a graft is not used and appears to be favoured by the femorotomy. Implantation of the long stem is not particularly difficult and can even make the operation easier. Femorotomy has a real advantage, particularly for the revision of septic stems or in the event of difficult explantation


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_1 | Pages 48 - 48
1 Jan 2018
Schreurs B Colo E Schmitz M Rijnen W Gardeniers J
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Total hip arthroplasty (THA) in patients under 30 years remains a challenge. The long-term survival data are often disappointing. In our institution, we have always used cemented components in all patients under 30 years, combined with acetabular impaction bone grafting (IBG), if necessary. We reviewed 139 consecutive patients (180 hips) treated between 1986 to 2014. Mean age at time of surgery was 24 (13–30.0) years. Acetabular IBG was applied in 127 (71%) cases. AAOS cavitary defect was seen in 26 (14%) cases, a AAOS segmental defect in 51 (28%) and a combination in 17 (9%). The mean preoperative HHS improved from 47 (20–81) to 87 (28–100) at review. During follow-up 26 hips have been revised (23 cups and 11 stems). Indications for revision were aseptic loosening (n=15), septic loosening (n=5), recurrent dislocation (n=3), wear (n=1), and stem fracture (n=1). The 10-year Kaplan-Meier survival of any component with endpoint revision for any reason was 87% (95% CI 79%–92%) and for aseptic loosening 92% (84%–96%). The 15-year survival of any component with revision for any reason as the endpoint was 77% (65%–86%) and for aseptic loosening 84% (71%–92%). Cemented THA and, if needed with impaction bone grafting, in patients under 30 years provides satisfying long-term results up to 15 years after surgery. Probably this biological approach with IBG may facilitate the inevitable revisions in the future in these young patients because of more bone stock


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_1 | Pages 8 - 8
1 Jan 2018
Eachempati K Malhotra R Guravareddy A Ashokkumar P Gowtam D Sheth N Suryanarayan P
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The advent of trabecular metal (TM) augments has revolutionized the management of severe bone defects during acetabular reconstruction. The purpose of this study was to evaluate patients undergoing revision total hip arthroplasty (THA) with the use of TM augments for reconstruction of Paprosky 3A, 3B defects and defects associated with pelvic discontinuity. A retrospective study was conducted of the cases performed at four centers between August 2007 and January 2015. Patients treated with TM augments for Paprosky 3A, 3B or chronic pelvic discontinuity were included in the study. All surgeries were performed through a posterior approach. A total of 57 patients (Male 34 (69%), Female 23(31%)), mean age 54 years (range, 28–94 years), with minimum follow up of one-year were included and evaluated using intention to treat analysis. There were 44 (77%) patients with a 3A defect, 11(19%) patients with a 3B defect (6 had an associated pelvic discontinuity), and 2 (3.5%) with a 2C defect and associated pelvic discontinuity. The mean follow-up was 37 months (range, 12–96 months). One (2%) patient died after 8 years of unrelated causes. Three (5.5%) patients had acetabular component loosening requiring revision; Two failures were (3.5%) due to aseptic loosening and one (2%) due to septic loosening. Fifty-four patients had a radiologically stable integration of the components at latest follow-up - survivorship was 94.7%. The results of this multi-center study demonstrate encouraging short and mid-term results for the use of TM augments in the management of Grade 3A and 3B defects, and defects associated with a chronic pelvic discontinuity


The Journal of Bone & Joint Surgery British Volume
Vol. 89-B, Issue 8 | Pages 1084 - 1087
1 Aug 2007
Bruns J Delling G Gruber H Lohmann CH Habermann CR

We reviewed 25 patients in whom a MUTARS megaprosthesis with a conical fluted stem had been implanted. There were three types of stem: a standard stem was used in 17 cases (three in the proximal femur, nine in the distal femur and five proximal tibia), a custom-made proximal femoral stem in four cases and a custom-made distal femoral stem in four cases. The mean age of the patients was 40.1 years (17 to 70) and the mean follow-up was for 2.5 years (0.9 to 7.4). At follow-up two patients had died from their disease: one was alive with disease and 22 were disease-free. One of 23 prostheses had been removed for infection and another revised to a cemented stem. The mean Musculoskeletal Tumor Society score was 24.9 (12 to 30) and the mean Karnofsky index was 82% (60% to 100%). There was no radiological evidence of loosening or subsidence. Stem stress shielding was seen in 11 patients and was marked in five of these. There were five complications, rupture of the extensor mechanism of the knee after extra-articular resection in two patients, deep venous thrombosis in one, septic loosening in one, and dislocation of the hip in one. The survival rate after seven years was 87% (95% confidence interval (CI) 83 to 91) for the patients and 95% (95% CI 91 to 99) for the megaprosthesis. A longer follow-up is needed to confirm these encouraging results


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_17 | Pages 26 - 26
1 Nov 2017
Syam K Wilson-Theaker W Lokikere N Saraogi A Gambhir A Porter M Shah N
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With increasing burden of revision hip arthroplasty, one of the major challenge is the management of bone loss associated with previous multiple surgeries. Proximal femoral replacement (PFR) has already been popularised for tumour surgeries. The inherent advantages of PFR over allograft –prosthesis system, which is the other option for addressing severe bone loss include, early weight bearing and avoidance of non-union and disease transmission. Our study explores PFR as a possible solution for the management of complex hip revisions. Thirty consecutive hips (29 patients) that underwent PFR between January 2009 and December 2015 were reviewed retrospectively for their clinical and radiological outcomes. The Stanmore METS system was used in all these patients. Mean age at the index surgery (PFR) was 72.69 years (range 50–89) with number of previous hip arthroplasties ranging from 1–5. At mean follow up of 32.27 months, there were no peri-prosthetic fractures and no mechanical failure of the implants. Clearance of infection was achieved in 80% of cases. There was 1 early failure due to intra-operative perforation of femoral canal needing further revision and two were revised for deep infection. Instability was noted in 26.7% (8) of the hips, of which, 87.5% (7) needed further revision with constrained sockets. Out of these 8 hips with instability, 5 had pre-operative infection. Deep infection was noted in 20% (6) of the hips, of which, 5 were primarily revised with PFR for septic loosening. However, further surgeries were essential for only 3 patients. One patient has symptomatic aseptic acetabular loosening and 1 had asymptomatic progressive femoral side loosening (lost to follow up). Severe proximal femoral bone loss in complex revision arthroplasties has necessitated the use of PFR prosthesis. Our study supports the fact that PFR is probably a mechanically viable option for complex revisions. Significant numbers of dislocations and infections could be attributed to the poor soft tissue envelope around the hip. Further surgical techniques in the form use of dual mobility cups and silver coated PFR implants need to be explored


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_21 | Pages 86 - 86
1 Dec 2016
Philippot R Boyer B Neri T Farizon F
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The main causes of total hip arthroplasty (THA) revisions are loosening and instability. Use of a dual mobility cup cemented in a acetabular reconstruction cage device limits the risk of instability and does not hinder the acetabular fixation during THA revisions. The objective of this study was to analyse a retrospective series of 123 THA revisions with antiprotusio cage and dual mobility socket. Patients and methods: At a mean follow-up of 10 years, we analysed a continuous series of 123 revisions using a reconstruction device (87 Kerboull cross-plates, 12 Burch-Schneider antiprotrusio cages, 24 custom-fit Novae ARM cages associated in all cases with a Novae Stick dual mobility cup cemented into the cage). There were 80 women and 43 males. The mean age at the surgery was 69.2 years old. PMA score increased from 9.6 +/− 3.06 preoperatively to 14.2 +/− 2. at the follow-up. 9 early dislocations occurred and one late dislocation. At the last follow-up, the X-rays showed nine hardware failures, including one cross-plate fracture, one hook fracture, and one flange fracture. Analysis of the radiological position of the cup showed a mean lowering of 13 mm and a 7 mm lateralisation compared to the preoperative position. 2 revisions for aseptic loosening and 3 for septic loosening were performed. This study confirms the advantage of dual mobility cups during acetabular reconstruction cemented in antiprotrusio cages as a way to limit, without eliminating, the risk of dislocation. Therefore cemented fixation of dual mobility cups in cages appears to be a reliable short-term option


The Bone & Joint Journal
Vol. 104-B, Issue 3 | Pages 368 - 375
1 Mar 2022
Kuijpers MFL Colo E Schmitz MWJL Hannink G Rijnen WHC Schreurs BW

Aims

The aim of this study was to determine the outcome of all primary total hip arthroplasties (THAs) and their subsequent revision procedures in patients aged under 50 years performed at our institution.

Methods

All 1,049 primary THAs which were undertaken in 860 patients aged under 50 years between 1988 and 2018 in our tertiary care institution were included. We used cemented implants in both primary and revision surgery. Impaction bone grafting was used in patients with acetabular or femoral bone defects. Kaplan-Meier analyses were used to determine the survival of primary and revision THA with the endpoint of revision for any reason, and of revision for aseptic loosening.


Bone & Joint Open
Vol. 3, Issue 11 | Pages 867 - 876
10 Nov 2022
Winther SS Petersen M Yilmaz M Kaltoft NS Stürup J Winther NS

Aims

Pelvic discontinuity is a rare but increasingly common complication of total hip arthroplasty (THA). This single-centre study evaluated the performance of custom-made triflange acetabular components in acetabular reconstruction with pelvic discontinuity by determining: 1) revision and overall implant survival rates; 2) discontinuity healing rate; and 3) Harris Hip Score (HHS).

Methods

Retrospectively collected data of 38 patients (39 hips) with pelvic discontinuity treated with revision THA using a custom-made triflange acetabular component were analyzed. Minimum follow-up was two years (mean 5.1 years (2 to 11)).


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_4 | Pages 67 - 67
1 Feb 2017
Kim J Baek S Kim S
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Introduction. The mid- or long-term results of acetabular revision total hip arthroplasty (THA) in Korea are rare. The purpose of this study is to report the mid-term radiographic results (> 5 years) of acetabular revision THA with porous-coated cementless Trilogy. ®. cup (Zimmer, Warsaw, IN, USA). Materials and Methods. Between 1999 and 2010, 77 patients (79 hips) had underwent acetabular revision THA with Trilogy. ®. cup. Eight patients (8 hips) were excluded due to death before 5-year follow-up, and 22 patients (23 hips) were excluded due to less than 5-year follow-up or follow-up loss. Forty-seven patients (48 hips) were included in our study. The mean age was 57.9 years (range, 36 to 76 years) and the mean follow-up was 9.8 years (range 5.0 to 16.2 years). The causes of revision were aseptic loosening in 40 hips, and septic loosening in 8 hips, respectively. Both acetabular and femoral revisions were performed in 14 hips and isolated acetabular revision was done in 34 hips. Preoperetive acetabular bone defect according to Paprosky classification was; 1 in type I, 6 in IIA, 11 in IIB, 9 in IIC, 15 in IIIA, and 6 in IIIB. Results. Radiolucent lines less than 2mm were found in 2 hips; one in zone I, another in zone I, II, III. Four hips (1 in type IIC, 1 in IIIA and 2 in IIIB) showed cup migration greater than 5 mm accompanying change of position greater than 5 degrees. However, these patients did not complain pain and showed fixation by secondary stabilization. The Kaplan-Meier survivorship with aseptic loosening as the end point at 10 years was 92.6% (95% confidence interval [CI], 82.6 – 100) and at 15 years was 83.8 % (95% CI, 69.1 – 98.6), respectively. Non-recurrent dislocations occurred in 4 hips. There were no other complication such as sciatic nerve palsy, infection and deep vein thrombosis. Conclusion. Mid-term radiographic results (>5 years) of acetabular revision THA with porous-coated cementless Trilogy. ®. cup showed durable longevity. However, other options such as anti-protrusio cage or cup-cage construct should be considered in severe acetabular bone defect


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_16 | Pages 36 - 36
1 Dec 2015
Lepetsos P Stylianakis A Leonidou A Argyris D Anastasopoulos P Lelekis M Tsiridis E Macheras G
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In spite of its incidence decreasing to 1% nowadays, prosthesis-related infections remain a research, diagnostic, therapeutic and cost-related problem. Early diagnosis, selection of an appropriate surgical strategy, accurate identification of the responsible microorganisms and construction of an appropriate antibiotic regimen are essential elements of any management strategy. Our study aim was firstly to compare the diagnostic accuracy of conventional periprosthetic tissue culture and culture of fluid derived from vortexing and bath sonication of the explanted hardware and secondly to investigate the role of possible metabolic factors affecting the sensitivity of the sonication method. We investigated 70 patients undergoing revision hip or knee arthroplasty because of loosening of the prostheses, at our institution, between October 2011 and November 2013. Patients’ medical history and demographic characteristics were recorded. We compared the culture of samples obtained by sonication of explanted hip and knee prostheses with conventional culture of periprosthetic tissue for the microbiological diagnosis of prosthetic-joint infection. Infectious Diseases Society of America (IDSA) Guidelines were used for the definition of prosthetic-joint infection. Thirty-two patients had septic loosening and 38 aseptic loosening (48 hip prostheses and 22 knee prostheses). The sensitivity of sonication fluid culture was 81.25% and the sensitivity of conventional tissue cultures was 56.25% (p-value = 0.043). The sensitivity of the sonication method was statistically higher in obese, diabetic patients, with age above 60, in uncemented arthroplasties and in arthroplasties because of primary osteoarthritis (p-values < 0.05). The sonication method represents a reliable test for the diagnosis of prosthetic – joint infections with a greater sensitivity than the conventional periprosthetic tissue cultures, especially in obese, diabetic patients, with age above 60, in uncemented arthroplasties and in arthroplasties because of primary osteoarthritis


The Bone & Joint Journal
Vol. 106-B, Issue 3 Supple A | Pages 110 - 114
1 Mar 2024
Yee AHF Chan VWK Fu H Chan P Chiu KY

Aims

The aim of this study was to evaluate the survival of a collarless, straight, hydroxyapatite-coated femoral stem in total hip arthroplasty (THA) at a minimum follow-up of 20 years.

Methods

We reviewed the results of 165 THAs using the Omnifit HA system in 138 patients, performed between August 1993 and December 1999. The mean age of the patients at the time of surgery was 46 years (20 to 77). Avascular necrosis was the most common indication for THA, followed by ankylosing spondylitis and primary osteoarthritis. The mean follow-up was 22 years (20 to 31). At 20 and 25 years, 113 THAs in 91 patients and 63 THAs in 55 patients were available for review, respectively, while others died or were lost to follow-up. Kaplan-Meier analysis was performed to evaluate the survival of the stem. Radiographs were reviewed regularly, and the stability of the stem was evaluated using the Engh classification.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_34 | Pages 230 - 230
1 Dec 2013
Bassiony A Asal MK
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Failure of the femoral component after a primary or revision THA is commonly associated with some degree of femoral bone loss. Depending on the quantity and quality of the remaining host bone, femoral stem revision can be challenging. Twenty patients with severe proximal femoral bone loss due to prosthetic loosening were treated by Wagner cementless self-locking revision stems with a mean follow up of 24 months (range 18–36 months). The indication of revision surgery was aseptic loosening in 16 patients and septic loosening in 4 cases. At the end of the follow up the mean Harris hip score increased from 35 to 86 points. Definite radiographic evidence of bone regeneration in the bony defects was achieved within 3 months in all patients. Implantation of a Wagner cementless selflocking revision stem provided satisfactory results. The Wagner SL Revision prosthesis, firmly and rotationally stable fixed in the medullary cavity of the healthy bone distal from the original prosthetic bed, with its conical longitudinal ribs and cementless anchorage, bridges the defective prosthetic bed and hereby leads to a condition of relative mechanical stability. With time, there is active ossification in the old prosthetic bed, replacing lost bone


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_9 | Pages 137 - 137
1 May 2016
Pramhas D Knahr K Dominkus M
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Introduction. The legacy constrained condylar knee prosthesis (LCCK, Zimmer.) is designed for primary and revision total joint arthroplasties that need additional stability due to ligament deficiency and to compensate for bone defects. In this follow-up we present our mid term results. Methods and Material. Between November 1999 and January 2006 59 patients were provided with 67 LCCK knee endoprotheses. 38 prostheses were implanted in cases of revision surgery and 29 as primary implants. The mean patient age was 76 years (range 22–93). Indications for revisions were 20 aseptic loosenings, 11 late infections, 7 instabilities (5 cases due to polyethylene wear). Indications for primary arthroplasties were 16 severe valgus and 7 severe varus deformities, 5 cases of osteoarthritis after infection and 1 posttraumatic deformity. 36 femur components (54%) and 34 tibia components (51%) were augmented. 31 stems were fixed cementless, 15 stems were cemented (6 with an intermedullary plug). We evaluated the results prospectively with a clinical inspection and x-ray. Clinical rating systems used were the Knee society, SF-36 Quality of life and Womac score. The mean follow up was 5.6 years. 42 patients were examined, 10 questioned on the telephone, 3 deceased, 12 had to be revised and 2 were lost for follow-up. Results. We had an increase in ROM from 93° to 110°. The Knee Society score improved from 40 to 75 and the function score improved from 46 to 72. The early complications included 1 peroneal lesion, 1 intraoperative fracture, 7 limitations in movement, 10 wound healing problems and 1 thrombosis. 12 revisions had to be performed. 1 septic loosening, 1 synovectomy, 4 aseptic loosenings, 3 secondary patella replacements, 1 traumatic rupture of the quadriceps muscle, 1 chondrosacroma and 1 revision performed in another clinic. 25 (80%) uncemented stems, 3 (33%) cemented stems and 1 (17%) of the stems cemented with an intramedullary plug showed radiolucencies. Conclusion. The LCCK prosthesis can be recommended as a primary implant and for revisions in cases of severe instability or severe bone loss. Due to the bad general health of the patients and preoperative situation of the knee joints the results are satisfactory. All revisions due to aseptic loosening had to be performed on LCCKs with uncemented stems


The Bone & Joint Journal
Vol. 104-B, Issue 9 | Pages 1039 - 1046
1 Sep 2022
Özdemir E Kuijpers MFL Visser J Schreurs BW Rijnen WHC

Aims

The aim of this study is to report the long-term outcomes of instrumented femoral revisions with impaction allograft bone grafting (IBG) using the X-change femoral revision system at 30 years after introduction of the technique.

Methods

We updated the outcomes of our previous study, based on 208 consecutive revisions using IBG and the X-change femoral revision system in combination with a cemented polished stem, performed in our tertiary care institute between 1991 and 2007. Kaplan-Meier survival analyses were used to determine the survival rate of the revisions with endpoint revision for any reason and aseptic loosening. Secondary outcomes were radiological loosening and patient-reported outcome measures.


Bone & Joint Open
Vol. 4, Issue 7 | Pages 539 - 550
21 Jul 2023
Banducci E Al Muderis M Lu W Bested SR

Aims

Safety concerns surrounding osseointegration are a significant barrier to replacing socket prosthesis as the standard of care following limb amputation. While implanted osseointegrated prostheses traditionally occur in two stages, a one-stage approach has emerged. Currently, there is no existing comparison of the outcomes of these different approaches. To address safety concerns, this study sought to determine whether a one-stage osseointegration procedure is associated with fewer adverse events than the two-staged approach.

Methods

A comprehensive electronic search and quantitative data analysis from eligible studies were performed. Inclusion criteria were adults with a limb amputation managed with a one- or two-stage osseointegration procedure with follow-up reporting of complications.


Bone & Joint Open
Vol. 4, Issue 2 | Pages 110 - 119
21 Feb 2023
Macken AA Prkić A van Oost I Spekenbrink-Spooren A The B Eygendaal D

Aims

The aim of this study is to report the implant survival and factors associated with revision of total elbow arthroplasty (TEA) using data from the Dutch national registry.

Methods

All TEAs recorded in the Dutch national registry between 2014 and 2020 were included. The Kaplan-Meier method was used for survival analysis, and a logistic regression model was used to assess the factors associated with revision.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_9 | Pages 136 - 136
1 May 2016
Porporati A Streicher R
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INTRODUCTION. Wear, aseptic loosening, dislocation, corrosion and prosthetic joint infection (PJI) are major factors leading to revision of THA. The effect of using ceramic components to address these issues was investigated to determine their behaviour and potential benefit. METHODS. a) Wear determination in off-normal conditions. A series of CoC articulations (32mm) was evaluated using a hip simulator (ISO 14242) up to 4 million cycles in presence of fine alumina particles (48mg/ml). Wear was measured gravimetrically. b) Friction moment determination. Friction moments were measured in a hip simulator with 25% newborn calf serum as lubricant. CoC, CoPE, MoPE, MoXLPE and CoXLPE with articulating diameters ranging between 28 and 40mm were used. The cup was inclined to a constant angle of 33° and rotated ±20° sinusoidally around a horizontal axis at 1Hz. Peak friction moments were measured around the cup rotation axis during a constant joint force period of 1700N between 200 and 210 seconds. c) Infections. Four databases were analysed and additionally data from registers and literature were reviewed to determine the risk of revision for prosthetic joint infection (PJI) dependence on the bearing. Only data for cementless THA were used. Several studies also included analysis of several confounding factors like age at surgery, BMI, pathology, etc. using Cox multivariate analysis. RESULTS. a) Wear determination in off-normal conditions. Loading the test medium with alumina particles didn't produces detectable wear. Opaque areas appeared only after 3 million load cycles, but the wear-rate remained within the gravimetric measurement detection limit (about 0.1–0.2mg) indicating the still extremely low wear-rate of the tested couplings. b) Friction moment determination. The highest moments were measured for metal heads; the lowest for CoC bearings. 40mm CoC bearing showed a similar friction moment like 28mm bearings when coupled with a XLPE liner. c) Infections. The rate of revisions for PJI for 500'749 patients from various studies was in the range of 0.2 to 1.1%. Age at surgery and BMI did not influence septic loosening, while the bearing did; sometimes significant. The trend was identical for all seven sources and ceramic components resulted in a lower incidence of revisions for up to 60%. CONCLUSION. The wear of CoC articulations is extremely low even in a heavily contaminated environment with fine hard particles. Such high scratch resistance makes CoC the preferable revision solution in THA. Friction moments with CoC are the lowest, even with large diameter bearings. The low friction moments of ceramics lower the stresses at the modular and also bone interface and can affect the outcome of THA. Revisions due to infection seem to be also dependent on the bearing couple with a positive influence of ceramic components. Although due to the complex reasons for infections only a trend, CoP and CoC has been identified to mitigate the risk of PJI


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_9 | Pages 106 - 106
1 May 2016
Pace F Randelli P Favilla S Brioschi M Maglione D Visentin O Randelli F
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Introduction. The dual mobility cup was introduced in the 1970s to allow extensive range of motion associated with great stability thanks to double articulation; the first between the head and polyethylene, the second between the polyethylene and the cup. The original plan was to install a stainless-steel uncemented cup coated with a thin layer of alumina and a metal head of 22,2 mm with a polyethylene liner of first generation. Long term follow-up case studies are cited in the literature showing excellent results in reducing dislocations; however wearing and aseptic loosening are noted. The new dual-mobility cups, with reticular polyethylene and titanium and hydroxyapatite coating are proving as reliable as the older ones in terms of stability whilst they appear to be more durable. Furthermore, cemented dual-mobility cups are available, these are the topic of this study. One of the most frequent complications in the major revisions of hip replacement is dislocation. This study summarises our experience gathered in the use of dual-mobility cups during revisions of complex cases (GIR III-IV femoral or acetabular). Materials and Methods. Between July 2014 to March 2015, we have implanted 13 cemented cups with dual-mobility (Avantage® Biomet) each in different patients, who have undergone revision with severe ostheolysis (GIR III-IV femoral or acetabular). The mean age of patients was 71.5 years old (46 to 89). Indications for revisions were: aseptic loosening in 7 patients (two at third surgery), recurrent dislocation in 3 patients, 1 septic loosening, 1 revision after spacer removal e 1 post-traumatic. We used dual-mobility cup in revision surgery when implant stability could have been compromised due to difficult positioning of acetabular component in cases of walls defects or muscolar laxity. The patients have been evaluated clinically and radiographically. Results. In most difficult cases with a severe lack of acetabular walls (9 patients), and thus difficulties in correct cup positioning, we have choosen to implant a cemented cup inside a Burch-schneider® (Zimmer) ring; in those cases where acetabular morphology was still sufficient, a dual-mobility cup was directly cemented to the bone. No dislocations occured during the folllow-up, neither infections, neurological events or DVT. Discussion. Dual mobility cups are often used both as primary implant or as a revision cup. Dislocation rate in primary total hip replacement is comparable to other kind of cup normally used, while in revision cases, the incidence of dislocation decrease from a range of 5–30% to 1,1–5,5%. Our results are not yet comparable to those in literature due to short follow-up, but first impressions are comforting thanks to the lack of dislocation even in really severe cases. Conclusions. The dual-mobility cup in acetabular revisions, is one of the possible choice to keep in mind in more complex cases, where obtaining stability is difficult or impossible using other revision implants. In the literature, the available follow up are not yet long enough to be sure of implant longevity and so it's important to pay attention to use this cup in those patients with long life expectancy


The Bone & Joint Journal
Vol. 95-B, Issue 2 | Pages 166 - 172
1 Feb 2013
Abolghasemian M Tangsataporn S Sternheim A Backstein D Safir O Gross AE

Trabecular metal (TM) augments are a relatively new option for reconstructing segmental bone loss during acetabular revision. We studied 34 failed hip replacements in 34 patients that were revised between October 2003 and March 2010 using a TM acetabular shell and one or two augments. The mean age of the patients at the time of surgery was 69.3 years (46 to 86) and the mean follow-up was 64.5 months (27 to 107). In all, 18 patients had a minor column defect, 14 had a major column defect, and two were associated with pelvic discontinuity. The hip centre of rotation was restored in 27 patients (79.4%). The Oxford hip score increased from a mean of 15.4 points (6 to 25) before revision to a mean of 37.7 (29 to 47) at the final follow-up. There were three aseptic loosenings of the construct, two of them in the patients with pelvic discontinuity. One septic loosening also occurred in a patient who had previously had an infected hip replacement. The augments remained stable in two of the failed hips. Whenever there was a loose acetabular component in contact with a stable augment, progressive metal debris shedding was evident on the serial radiographs. Complications included another deep infection treated without revision surgery. Good clinical and radiological results can be expected for bone-deficient acetabula treated by a TM cup and augment, but for pelvic discontinuities this might not be a reliable option. Cite this article: Bone Joint J 2013;95-B:166–72


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXV | Pages 11 - 11
1 Jun 2012
Bassiony A
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Background. Revision THA presents significant challenges for the surgeon when the proximal femur is deficient or mechanically unreliable. The aim of this study is to assess the clinical and functional results of the use of tumor enndoprosthesis to reconstruct the proximal femur when there is massive bone loss. Patients and Methods. A prospective study was conducted involving 10 cases. The follow up of the cases ranged from 12 months to 30 months with a mean period of an average of 23months. The indications for revision surgery were aseptic loosening in 9 cases and septic loosening in one case Harris hip score was used for pre and postoperative clinical evaluation of the patients. Results. At the latest follow up the Harris Hip scores improved from a preoperative average of 16 (range, 3-47), to a postoperative average of 75.6 (range, 66-94). The complications that we encountered in the study included one case of superficial wound infection, another case developed sciatic nerve palsy postoperatively. No other complications were reported. Conclusion. Revision hip replacement in proximally compromised femurs presents a significant surgical challenge. When there is massive proximal femoral bone loss proximal fitting revision stems do not achieve adequate fixation hence the use of tumor prosthesis is indicated


Bone & Joint 360
Vol. 11, Issue 4 | Pages 17 - 21
1 Aug 2022


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XL | Pages 207 - 207
1 Sep 2012
Vervest T Busch V van Susante J Laumen A
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Introduction. Total hip arthroplasty in young patients is still associated with high failure rates, especially at the acetabular side. Purpose of this study was to evaluate the long-term results of the Alloclassic cementless Zweymüller total hip prosthesis in patients younger than 50 years at the time of surgery. Methods. Between 1987 and 1994, 73 Zweymüller total hip arthroplasties with a titanium threaded cup were placed in 67 patients younger than 50 years. Mean age at surgery was 43 years (23–49 years). Patients were followed clinically with use of the HHS, revisions were determined and radiographs were analyzed. Kaplan-meier analysis was used to determine survival for different endpoints. Results. Three hips were revised for septic loosening, 3 cups for aseptic loosening and 1 hip because of periprosthetic fracture. Four patients (4 hips) died and 8 patients (9 hips) were lost to follow-up without any revision. 48 patients with 53 prostheses could be evaluated after a mean follow-up of 208 (170–253) months and the mean HHS was 90 (52–100). Cumulative survival analysis with endpoint revision for any reason was 89% (C.I. 85–93) at 17 years. With endpoint aseptic loosening, survival was 95% (C.I. 91–98) at 17 years. Conclusion. Alloclassic Zweymüller total hip arthroplasty with a titanium threaded cup showed good long-term results, even in this group of patients younger than 50 years


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_34 | Pages 327 - 327
1 Dec 2013
Greber E Bushmiaer M Barnes L
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Background:. Until recently, there has been no consensus of the best approach to dIfferentiating aseptic from septic loosening in joint replacement patients. The recent AAOS Clinical Practice Guideline Summary that was published in 2010, tasks orthopedic surgeons with the strong recommendation of obtaining ESR and CRP for all patients needing hip and knee arthroplasty revision surgery and aspirating the joint based upon these results. The purpose of this study is to determine from our patients whether this guideline has been helpful and cost effective in determining periprosthetic joint infections. Methods:. We retrospectively reviewed charts of 50 consecutive patients who underwent revision total hip or knee arthroplasty. Each patient received an ESR and CRP level prior to operation and patients with known periprosthetic joint infections were excluded from the study. As guidelines recommend, aspiration with cultures and cell count were obtained on all knees with either elevated ESR or CRP and all hips with both ESR and CRP elevated. We then determined how many patients needing revision arthroplasty of the hip or knee benefited from ESR, CRP, and aspiration by finding subclinical periprosthetic infection and changing the intraoperative treatment. Hospital charge data was used to report cost of this protocol. Results. Sixty-four percent (32/50) patients had elevated ESR and/or CRP. Eighteen patients (12 hips; 7 knees) required joint aspirations per the guidelines. None of the aspirations were positive for bacterial growth. The total hospital charges for aspiration and cultures in this patient population were $81, 712.44. No sub clinical infection was identified. Conclusion:. Although guidelines may more readily diagnose every case of subclinical joint infection, we must continue to evaluate the cost of this type protocol in a busy revision practice


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_8 | Pages 134 - 134
1 May 2016
Lapaj L Mroz A Wendland J Markuszewski J
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Introduction. Titanium nitride (TiN) coatings are used in total hip arthroplasty to reduce friction of bearing couples or to decrease the allergic potential of orthopaedic alloys. Little is known about performance of currently manufactured implants, since only few retrieval studies were performed, furthermore they included a small number of implants manufactured over 15 years ago. Aim of study. To examine wear and degradation of retrieved TiN coated femoral heads articulating with ultra-high molecular weight polyethylene (UHMWPE). Methods. We included eight femoral heads with a made od TiAl6V4 alloy and coated with TiN using Physical Vapour Deposition (PVD). All heads (28 and 32 mm) were retrieved after at least 12 months of use (range 12–56). The reason for revision was aseptic loosening in 6 cases, septic loosening in one case and recurrent dislocations (five episodes) in one uncemented prosthesis. One unused head was included as reference sample. All implants were evaluated with light microscopy, Scanning Electron Microscopy (SEM) with Energy-Dispersive X-ray Spectroscopy (EDS). 30 SEM images from each implant were digitally analysed using ImageJ software to compare damage in loaded and non weight-bearing parts of the heads. Results. Studies with light microscopy revealed severe damage to the dislocated femoral head, with multiple metallic scratches. SEM studies indicated presence of multiple scratches and pinholes with a diameter of 1–10 µm (Fig1a,b,). Residue from the manufacturing process was present in all implants in form of pure Ti droplets found in round voids. In all implants we found irregular areas (diam. 20–50 µm, Fig 1c,d) where the coating was delaminated from the substrate metal with cracks arising from coating defects (Fig1e-h). Some of these debonded fragments were embedded into the PVD layer in weight-bearing parts of all heads. In one head, which was subjected to dislocations we observed deposits of titanium alloy from the acetabular shell (Fig 2a,b). The deposits were accompanied by large patches of delaminated coating as well as multiple cracks (Fig 2c,d). Small fragments of the acetabular titanium alloy damaged the coating in third body mechanism. Surprisingly in three implants we EDS analysis revealed similar spheres (diam. 1–10 µm) containing Niobium (Nb), although this element is not a part of any of the components used in the implants(Fig 2e,f). Interestingly presence of Nb droplets were associated with a higher number of other defect in these heads both in weight-baring and non weight-bearing parts of the heads suggesting inferior coating quality in these cases (Fig 2 g,h; Fig3, cases H2,H5,H8). Conclusions. Compared to previous studies we did not observe severe wear or the coating, however we observed some degradation of the film in vivo. Our results indicate that dislocation can lead to severe failure of the coating in vivo. Moreover presence of Nb residues and coexisting defects in some implants suggests inferior coating quality in these implants and indicates the need for strict monitoring of the production process. This study was funded by a grant from the National Science Centre nr 2012/05/D/NZ5/01840


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXV | Pages 189 - 189
1 Jun 2012
Pignatti G Dallari D Rani N Stagni C Piccolo ND Giunti A
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INTRODUCTION. Since July 2008 we are experimenting a new cup with iliac screw fixation, developed on the idea of Ring and Mc Minn. Iliac fixation is permitted by a polar screw of large diameter, coated by HA, which allows a compression to bone and a firm primary stability. Moreover it's possible to increase primary stability with further smaller peripherals screws. We present this new cup and report the preliminary results. MATERIALS AND METHOD. Since July 2008 to April 2010, 51 cups were implanted. The diagnosis was aseptic loosening in 36 cases, septic loosening treated by two-stage revision in 7, hip congenital dislocation in 5, one case of post-traumatic osteoarthritis, one case of instability due to cup malposition and a case was an outcome of Girdlestone resection arthroplasty. Mean age was of 66 years (31-90). RESULTS. We report the results of our first 23 cases, with a minimal follow-up of 12 months. Patients were preoperatively evaluated from both clinical and radiological point of view. Bone defect was analyzed according to the system of Paprosky. In 7 cases bone defect belonged to type 2C, in 8 cases to type 3A and in 8 cases to type 3B. We didn't observe any case of early loosening nor mechanical failure of the implant. The functional outcome, evaluated by Harris Hip Score, was good with a mean score of 82 (72-91)


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_21 | Pages 30 - 30
1 Apr 2013
Majeed H Sundarmoorthy D Dhar S
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Introduction. With increasing numbers of primary total ankle replacements being performed, the number of revision ankle surgeries is expected to rise also. We present the results of the revision procedures for failed Scandinavian total ankle replacements. Patients and methods. We retrospectively reviewed all the Scandinavian TAR done by the senior author from March 1999 till Jan 2006. Patients who underwent revision surgery were identified and their data was collected including indications for revision surgery, procedure performed, symptoms and the overall outcome. Results. 25 patients underwent revision of Scandinavian TARs between April 2000 and April 2012 out off a total of 213 primary STARs (11%). Average age was 68 years (45 to 82), with male to female ratio of 4:1. The causes of failure of primary implants included broken polyethylene inserts in 12 patients, aseptic loosening in 6 and ankle instability in 7 patients. No septic loosening was found in any of our patients. Revision procedures which were performed in these patients included exchange of inserts in 13 patients, revision of all components in 2, revision of tibial component in 3, talar component in 2 and ankle arthrodesis with hindfoot nail in 4 and with ilizarov frame in 1 patient. The average time from the primary procedure to revision surgery was 78 months (12 to 156). The average follow up after revision surgery was 26.5 months (2 to 57). Four patients have died. Two patients were symptomatic with mild pain and stiffness while the rest are asymptomatic after their revision surgery. Conclusion. In our study the mechanical failure was found to be the most common cause of failure of Scandinavian TARs. The outcome of revision surgery has been found to be satisfactory and comparable to other series that is reported in the literature


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_15 | Pages 159 - 159
1 Mar 2013
De Kam DC Busch VJ Gardeniers JW Veth RP Schreurs BW
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Introduction. Total hip arthroplasties in younger patients often requires revision because these patients frequently have acetabular deficiencies, which hamper proper implantation of the cup essential for good long-term prosthesis survival. For 30 years, we have used a biological acetabular-reconstruction technique with bone-impaction grafting in all patients <50 years with an acetabular deficiency at surgery, always in combination with a cemented total hip implant. Methods. We evaluated all 150 consecutive patients (177 hips) < 50 years with an acetabular reconstruction by bone-impaction grafting surgically-treated from 1978–2004 at our clinic. Mean follow-up was 10.3 (range, 2.0–28.3) years with no patient lost to follow-up. Mean index surgery age was 38.1 (range, 16–49) years. Clinical, radiological, and statistical analysis of all patients was performed. Results. Twenty-eight of 177 hips were revised at a mean of 10.5 years (range, 5 days to 23.2 years). Reasons for revision were: aseptic loosening (n=17), septic loosening (n=3), recurrent dislocations (n=3), traumatic loosening (n=2), neuropathy (n=1), wear (n=1), and fracture (n=1). Ten-year and 15-year survival with endpoint revision of any component for any reason was 91% and 78%. Ten-year survival with endpoint aseptic loosening was 96% for the cup and 97% for the stem. Conclusion. Performing a total hip implant in combination with acetabular bone impaction grafting in younger patients with acetabular bone stock loss seems to be an attractive approach as the long-term results are acceptable and fulfill the NICE-criteria, showing a ten -year survival of more than 90% with endpoint revisions for any reason


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 315 - 315
1 May 2010
Mayer W Wagner S Linke R Maegerlein S Jansson V Mueller P
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Introduction: Arthroplasty plays a growing role in our society today. Due to scientific and medical progress there are an increasing number of viable candidates and the improvement of quality of life thereafter speaks for itself. Even though the operations are largely successful, complications after joint replacement surgery occur frequently. Approximately 10% of lower limb arthroplasties need surgical revision, of which 70% are due to loosening. The purpose of this study was to assess the feasibility of 18-fluorodeoxyglucose positron emission tomography (18FFDG–PET) in detecting septic and aseptic endoprosthetic loosening of hip and knee endoprostheses. Materials and Methods: Thirty-three patients (age range: 45–90y) with lower limb arthroplasty complaints (74 prostheses) were studied preoperatively with 18F-FDG-PET. All patients underwent surgery at a later stage with microbiological culturing to differentiate aseptic and septic loosening and to confirm the final diagnosis. Prostheses were tested intraoperatively for stability and microbiology. Results: The sensitivity/specificity of 18F-FDG-PET towards implant loosening in the hip was 80%/87%, in the knee 56%/82%. The sensitivity/specificity for infectious loosening in hip replacement arthroplasties was 67%/83%, in the knee 14%/89%. Discussion: 18F-FDG-PET seems an excellent method for detecting hip endoprosthetic loosening and a moderate tool to diagnose hip implant infection. It should not be seen as the method of choice to diagnose knee endoprosthetic loosening and infection


The Bone & Joint Journal
Vol. 106-B, Issue 5 Supple B | Pages 54 - 58
1 May 2024
Wassilew GI Zimmerer A Fischer M Nonnenmacher L O'Hara L Hube R

Aims

The use of a porous metal shell supported by two augments with the ‘footing’ technique is one solution to manage Paprosky IIIB acetabular defects in revision total hip arthroplasty. The aim of this study was to assess the medium-term implant survival and radiological and clinical outcomes of this technique.

Methods

We undertook a retrospective, two-centre series of 39 hips in 39 patients (15 male, 24 female) treated with the ‘footing’ technique for Paprosky IIIB acetabular defects between 2007 and 2020. The median age at the time of surgery was 64.4 years (interquartile range (IQR) 54.4 to 71.0). The median follow-up was 3.9 years (IQR 3.1 to 7.0).


The Journal of Bone & Joint Surgery British Volume
Vol. 86-B, Issue 8 | Pages 1214 - 1219
1 Nov 2004
Jafri AA Green SM Partington PF McCaskie AW Muller SD

Fatigue fractures which originate at stress-concentrating voids located at the implant-cement interface are a potential cause of septic loosening of cemented femoral components. Heating of the component to 44°C is known to reduce the porosity of the cement-prosthesis interface. The temperature of the cement-bone interface was recorded intra-operatively as 32.3°C. A simulated femoral model was devised to study the effect of heating of the component on the implant-cement interface. Heating of the implant and vacuum mixing have a synergistic effect on the porosity of the implant-cement interface, and heating also reverses the gradients of microhardness in the mantle. Heating of the implant also reduces porosity at the interface depending on the temperature. A minimum difference in temperature between the implant and the bone of 3°C was required to produce this effect. The optimal difference was 7°C, representing a balance between maximal reduction of porosity and an increased risk of thermal injury. Using contemporary cementing techniques, heating the implant to 40°C is recommended to produce an optimum effect


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 353 - 353
1 Jul 2011
Babis G Sakellariou V Mazis G Tsouparopoulos B Soukakos P Hartofilakidis G
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The purpose of this study is to present early results, common pitfalls and management in in cases of revision hip arthroplsty in patients with congenital disease of the hip. From 2001 to 2006, 36 consecutive cemented THAs with a history of congenital hip disease were revised due to aseptic loosening (31 cases), stem fracture (3 cases), septic loosening (2 case). There were thirty patients, all females, with a mean age at revision 61.7 years (range, 40 to 76). The revision was performed after a mean 15.4 years post primary operation (range, 9 to 26). In 7 cases the cup only, in 5 cases the stem only, and in 24 cases both components were revised. The mean follow-up was 43 months (range, 24 to 84). There were 3 intraoperative femoral fractures managed with long stem and circlage wires. Postoperatively, 5 hips were infected and sustained a 2 stage revision using a cement spacer. 3 hips were revised due to loosening. 28 cups and 28 stems remained intact for an average 45.2 months (range, 24 to 84). The probability of survival at 48 months was 76.3% (±9.7%) for the cups (12 components at risk) and 76.4% (±11.3%) for the stems (9 components at risk). Revision of a CDH arthroplasty is difficult and non predictable. Lack of acetabular bone stock and anatomical abnormalities of the femur lead to increased intra and postoperative complication rate


The Journal of Bone & Joint Surgery British Volume
Vol. 86-B, Issue 4 | Pages 492 - 497
1 May 2004
Schreurs BW Bolder SBT Gardeniers JWM Verdonschot N Slooff TJJH Veth RPH

This study presents the clinical and radiological results of 62 consecutive acetabular revisions in 58 patients, at a mean of 16.5 years follow-up (15 to 20). The Kaplan-Meier survivorship for the cup with end-point revisions for any reason, was 79% at 15 years (95% confidence interval (CI); 67 to 91). Excluding two revisions for septic loosening at three and six years, and one revision of a well-fixed cup after 12 years in the course of a femoral revision, the survivorship was 84% at 15 years (95% CI; 73 to 95). At review there were no additional cases of loosening, although seven acetabular reconstructions showed radiolucent lines in one or two zones. Acetabular revision using impacted large morsellised bone chips (0.7 cm to 1.0 cm) and a cemented cup, is a reliable technique of reconstruction, when assessed at more than 15 years


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 90 - 90
1 Sep 2012
Haverkamp D Somford M Klinkenbijl M Vis Van Der H Albers R
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Background. A lot of discussion persists whether obesity negatively influences the outcome of hip arthroplasty. Current literature does not answer this question, since manuscripts showing a worse outcome and those showing a similar outcome can both be found. We performed a meta-analysis with the primary research question whether obesity has a negative influence on short and long term outcome of total hip arthroplasty. Methods. A search of the literature was performed and studies comparing the outcome of hip arthroplasty in different weight groups were included. Methodology of the included studies was scored according to the Cochrane guidelines. Data extraction and pooling of the data was performed. For continuous data a weighted mean difference and for dichotomous variables a weighted Odds ratio was calculated. Heterogeneity was calculated using I2 statistics. Results. A total of 15 studies were available for data-extraction. Dislocation occurred more often in obese with an Odds ratio of 0.54 (95%CI: 0.38–0.75) (10 studies, n = 8634). Aseptic loosening occured more often in obese with an Odds ratio of 0.64 (95% CI 0.43–0.96)(6 studies, n = 5137). Infection occured more often in obese with an Odds Ratio of 0.3 (95%CI: 0.19–0.49) (10 studies, n = 7500). Venous thromboembolism occured more often in obese with an Odds Ratio of 0.56 (95%CI: 0.32–0.98) (7 studies, n = 3716). For septic loosening and intraoperative fractures no difference was found, probably due to low power. Subjective outcome measurements did not allow Pooling due to high heterogeneity (I2 = 68%). Conclusions. We conclude that being obese; ergo having a BMI of more than 30 certainly has a negative influence on total hip replacement


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 263 - 263
1 Mar 2004
Carrington R Skinner J Lewis A Bentley G
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Aims: The objective of this study was to clinically assess the outcome of CADCAM femoral components in the revision hip replacement. Methods: Between 1991 and 2000, 125 revision total hip replacements using CAD-CAM femoral components were performed. Clinical assessment was performed using the Harris Hip score, by direct patient consultation, and telephone or postal questionnaire. Survivorship was defined as the requirement for revision. Results: The patients were reviewed at a mean of 5.2 yrs (1 to 10). The mean Harris hip score increased from 44 points (range, 27 to 71 points) preoperatively to 71 points (range, 21 to 98 points) at the time of the most recent follow-up. 9 patients required subsequent revision; 4 for aseptic loosening, 1 for septic loosening and 4 for fracture of the femoral component. Conclusions: CAD-CAM technology provides a viable alternative to the challenge of revision hip surgery, with results comparable to other cementless techniques


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVI | Pages 37 - 37
1 Aug 2012
Al-Najjim M Chambers I
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Aims. To assess the early subsidence rate of the femoral stem for patients who had collarless Corail total hip replacement. Methods. Consecutive data was collected retrospectively between August 2007 and December 2009 for patients who had collarless Corail total hip replacement. Radiographic assessment of the degree of subsidence, calcar resorption, stem angulation, canal fill ratio and loosening of the stem were measured. Post operative pain, dislocation and stem revision surgery were also evaluated. Results. 48 patients were identified, providing 51 hips for the study. There were 22 male and 26 female. The mean age 64.2 years (range 38-77). Post-operative radiographs were taken at day 1, 6 weeks and one year post-operatively (range 10-18 months, mean 12.7). Significant subsidence was defined as 3 or more millimetres, we identified two patients with subsidence between 3-5mm, one patient with 6mm and two patients with 10mm subsidence at one year post-operatively. In the 5 patients with subsidence post-operatively, all significant subsidence occurred within the first 6 weeks. Canal fill ratio was measured in all patients; in the non-subsided group the ratio was an average of 72% in the lower third of the stem and 84% in the middle third. In the subsided group 75% in the lower third of the stem and 81% in the middle third, which we felt was clinically insignificant. There was no dislocation or revision for septic loosening. One patient with 10mm subsidence had liner revision for dissociation but the stem was well fixed and not revised. All patients who had significant subsidence still had functioning implants with no pain, revisions for subsidence or features of loosening. Discussion. There were no radiological features predictive of subsidence in our patients. Subsidence may be due to lack of compliance in some patients with partial weight bearing and increased Body Mass Index


The Journal of Bone & Joint Surgery British Volume
Vol. 78-B, Issue 2 | Pages 195 - 199
1 Mar 1996
Dickob M Martini T

We implanted 300 uncoated cementless PM prostheses into 271 patients and followed 251 (92.6%) of them for four to seven years. By then 37 had already been revised for aseptic and three for septic loosening. The survival rate with implant failure as the endpoint was 88.8% for the cup and 85.3% for the stem after six years. There was a higher risk of implant loosening in congenital dysplasia, unilateral hip arthroplasty and obesity. The results of 225 unrevised hip replacements were assessed by questionnaire. Only 27.4% of the patients were completely free from pain and 17.9% had pain on walking any distance or at all times. The walking distance was for less than 30 minutes in 40%. Because of the poor results in comparison with other prostheses we do not recommend further use of the uncoated PM prosthesis


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXV | Pages 75 - 75
1 Jun 2012
Gill I Krishnan M Reed M Partington P
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Introduction. To report the short to medium term results of acetabular reconstruction using reinforcement/reconstruction ring, morcellised femoral head allograft and cemented metal on metal cup. Methods. Single centre retrospective study of 6 consecutive patients who underwent acetabular reconstruction for revision hip surgery. The acetabulum was reconstructed using morcellised femoral head allograft and reinforcement or reconstruction ring fixed with screws. The Birmingham cup – designed for cementless fixation, was cemented into the ring in all cases. The uncemented Echelon stem with metal on metal modular head was used for reconstructing the femur. Data from our previous in-vitro study had shown good pull out strength of a cemented Birmingham cup. Results. There were 2 men and 4 women with a mean age of 75 years(57-83). Revision was performed for aseptic loosening in 2, septic loosening in 2 and peri-prosthetic fracture with loosening in 2 patients. All patients were reviewed clinically and radiographically at a mean of 36 months follow-up(range 24 - 42 months). Revision was not necessary in any patient for failure of acetabular or femoral fixation. However, 1 patient had revision to a proximal femoral replacement and constrained cup for recurrent infection and osteomyelitis at 24 months. This patient was excluded from the final analysis. The mean Harris hip score at last follow up was 79(range 70-89). Radiographic analysis revealed good graft incorporation and no signs of loosening or cup/ring migration. No dislocations or metal ion problems were recorded in this series. Conclusions. To the best our knowledge, this is the first series using cemented metal on metal cups within a reinforcement/reconstruction ring for revision hip arthroplasty. Excellent cemented fixation of the cup, manufactured for cementless fixation, was obtained at surgery with no evidence of loosening, and no dislocations at minimum 24 months follow up


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 176 - 176
1 Mar 2009
Mayer W Wagner S Linke R Maegerlein S Jansson V Müller P
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Introduction: Arthroplasty plays a growing role in our society today. Due to scientific and medical progress there are an increasing number of viable candidates and the improvement of quality of life thereafter speaks for itself. Even though the operations are largely successful, complications after joint replacement surgery occur frequently. Approximately 10% of lower limb arthroplasties need surgical revision, of which 70% are due to loosening. The purpose of this study was to assess the feasibility of 18-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) in detecting septic and aseptic endoprosthetic loosening of hip and knee endoprostheses. Materials and Methods: Thirty-three patients (age range: 45 – 90y) with lower limb arthroplasty complaints (74 prostheses) were studied preoperatively with 18F-FDG-PET. All patients underwent surgery at a later stage with microbiological culturing to differentiate aseptic and septic loosening and to confirm the final diagnosis. Prostheses were tested intraoperatively for stability and microbiology. Results: The sensitivity/specificity of 18F-FDG-PET towards implant loosening in the hip was 80%/87%, in the knee 56%/82%. The sensitivity/specificity for infectious loosening in hip replacement arthroplasties was 67%/83%, in the knee 14%/89%. Discussion: 18F-FDG-PET seems an excellent method for detecting hip endoprosthetic loosening and a moderate tool to diagnose hip implant infection. It should not be seen as the method of choice to diagnose knee endoprosthetic loosening and infection


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_15 | Pages 53 - 53
1 Mar 2013
De Kam DC Van Heumen MR Gardeniers JW Veth RP Schreurs BW
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Background. These days, total hip arthroplasties (THA) are more implanted in young patients. Due to the expected lifespan of a THA and the life expectancy of young patients, a future revision is inevitable. Indirectly increasing the number of revisions in these patients. Therefore we evaluated the results of revision THA in patients under the age of 60 years. However, we used a unique protocol in which we used in all cases of acetabular and/or femoral bone deficiencies reconstruction with bone impaction grafting. Methods. To determine the mid- to longterm results of cemented revision total hip arthroplasties in patients under the age of 60, all clinical data and radiographs were analyzed of patients operated between 1992 and 2005. Patients with multiple previous revisions were also included. Only cemented components were used. During this period 146 consecutive revision total hip arthroplasties were implanted in 129 patients. This included 124 cup and 106 stem revisions. The average age at index surgery was 47 years. No case was lost. Mean follow-up was 7.6 (range, 2.0–16.7) years. Results. Outcome of clinical questionnaires improved significantly after revision THA. During follow-up 19% (28 hips) needed a repeat revision (aseptic loosening 13, septic loosening 10, recurrent dislocations 2, traumatic loosening 2, and abductor contracture 1). Seven of 146 cases (4.8%) ended finally in a permanent Girdlestone. Seventeen (14%) of the 124 cups were radiographically loose, 11 were revised. Four (4%) of the 106 stems were radiographically loose, 2 were revised. The 10-years survival was 78% with endpoint revision for any reason and 87% with endpoint revision for aseptic loosening. 28 hips needed repeat revision after the index revision. No significant differences in survival were found looking at the different indications for revision. Conclusions. The survival of cemented revision THA in patients under the age of 60 is satisfying. Reconstruction of acetabular and femoral bone deficiencies with bone impaction grafting is a promising and biological attractive technique in this young and high demanding population and enhances the revisability of a THA


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_15 | Pages 55 - 55
1 Mar 2013
Di Giunta A Romano AM Susanna M Marcello Z
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Introduction. The following study start from an idea of the evaluation of the osteointegration in the bone cage of the Equinoxe Reverse shoulder prosthesis. The aim of the study is to assess the values of Bone Mineral Density (BMD) in periprosthetic areas, in patients undergoing shoulder arthroplasty with implants of the Equinoxe system by Excatech, Inc. To better understand the steps of osteointegration time of the bone cage with the glenoid. The objectives of the work are not only expanded to the value of osteointegration, but could also be useful for the evaluation of both mechanical and septic loosening of the stem of the glenoid. Materials and Methods. In the period from November 2011 to May 2012, 15 patients were evaluated. All patients were subjected to bone densitometry type of DXA within the first 15 days after surgery and at 3 months after surgery. The patients are all part of a homogeneous group for anatomical glenoid. Were excluded from the study all patients who were no significant alterations of the head and the glenoid. The acquisitions were performed with the patient in an oblique position, with limb in a neutral position, in order to obtain images in the coronal plane “true” of the joint. Were subsequently calculated values of BMD is around the stem with the 7 areas used by Gruen for the hip prosthesis and peripherally to the central peg using 3 areas, superiorly, medially and inferiorly to the same. Results. The values obtained showed a significant increase in the time of bone density peripherally to the central peg demonstrating a significant osteointegration. Being a prospective study these values will be integrated with new acquisition DXA to 6, 9, 12 months, 2, 3 and 5 years. Conclusions. Although preliminary, through our study it was possible to obtain the standard values of BMD in patients with prosthetic replacement has been successful. These BMD values represent a standard of reference for the physiological osseointegration; in the future must be evaluated for their variation in patients with prosthetic loosening and / or with infectious processes, in order to allow an early diagnosis of these diseases by studying DXA. Also in future studies BMD values obtained by us of the Equinoxe prosthesis can be compared with those obtained in other models of the shoulder prosthesis to detect any advantages or disadvantages in terms of osteointegration


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIX | Pages 125 - 125
1 Sep 2012
Templeton-Ward O Griffiths D Higgs D Falworth M Bayley I Lambert S
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Reverse polarity total shoulder arthroplasty (RTSA) has gained popularity over recent years for the treatment of the painful cuff deficient shoulder. Although proposed over 20 years ago and despite good clinical outcomes the RTSA has struggled to gain popularity due to reported high levels of complications. One such complication is post-operative instability with frequencies of up to 30% (De Wilde 2002). The Bayley-Walker RTSA was designed specifically for patients with difficult reconstruction problems in whom an unconstrained prosthesis would not offer sufficient stability. It is a reverse anatomy fixed fulcrum constrained prosthesis. The glenoid component has a long HA-coated tapered helical screw, with large pitch and depth, fixation is augmented by a grooved HA coated glenoid plate. The purpose of this study was to review the clinical experience from The Royal National Orthopaedic Hospital Stanmore and to ascertain the rate of glenoid component loosening. We also carried out a radiographic review to correlate loosening with patterns of lucency on post-operative radiographs. One hundred and five B-W TSRs in 103 patients were included, 24% of which were performed as revision of previous failed arthroplasty. In total, 8/105 glenoids required revision. Of those eight patients, two were cases of septic loosening. Of all nine specified areas of glenoid, tip lucency on x-ray appeared to be most strongly associated with need for glenoid revision. 5/9 cases with tip lucency progressed to loosening of the glenoid. Where tip lucency was not seen, 93/96 glenoid components remained secure, giving tip lucency a negative predictive value of 97%. Excluding the two infected cases, the glenoid remained secure in 97/103 patients undergoing BW-TSR with follow-up up to 13 years. The BW-TSR is a satisfactory and durable solution to the cuff-deficient shoulder in variety of challenging groups including younger patients and as a salvage procedure following failed, cuff-deficient arthroplasty


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 197 - 197
1 May 2011
Bori G Garcia S Font L Muñoz-Mahamud E Gallart X Mallofre C Riba J Mensa J Sierra J Tomas X Fuster D Zumbado A Soriano A
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Introduction: The histology of prosthetic tissue is a gold standard for the diagnosis of prosthetic joint infection. However, the specificity and sensitivity of histology has never been 100% and this could be due to several causes. A possible cause for inconsistencies in histological results could be the type of specimen submitted to laboratory. The majority of authors obtain specimens from pseudocapsule, interface membrane and any tissue area suspicious of infection. Aim: The objective of our study was to elucidate which is the most accurate specimen for histological diagnosis of prosthetic joint infection. Methods: Prospective study including all revision arthroplasties performed in Hospital Clinic of Barcelona (Spain) from January 2007 to June of 2009. Specimens from pseudocapsule and from interface membrane were obtained from each patient. Definitive diagnosis of infection was considered when ≥2 cultures were positive for the same microorganism or the presence of pus around the prosthesis. Patients were classified in two groups:. patients submitted to hip revision arthroplasty due to an aseptic loosening in whom cultures (at least 5) obtained during surgery were negative and. patients submitted to hip revision arthroplasty due to a septic loosening confirmed by the presence of pus or ≥2 positive culture for the same microorganism. Results: A total of 69 revisions were included in the study; 57 were classified in the group A and 12 were classified in the group B. The percentage of positive interface membrane histology in patients with prosthetic joint infection (group B) was significantly higher than the percentage of positive pseudocapsule histology (83.3% vs 41.6%, p=0.04, Fisher exact test). Conclusion: The results suggest that the best specimen of periprosthetic soft tissue for histological study to diagnose the chronic periprosthetic infection in a revision total hip arthroplasty is the periprosthetic interface membrane


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 209 - 209
1 Mar 2004
Schreurs B
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Aims: To reconstruct acetabular bone stock loss in revision hip surgery, from 1979 on we have used a biologic reconstruction method with tightly impacted cancellous allografts in combination with a cemented polyethylene cup. Methods: This studies presents the clinical and radiological results of 62 consecutive acetabular revisions in 58 patients at a mean of 16.5 years (15–20 years) followup. The Kaplan-Meier survivorship for the cup with end-point revisions for any reason was 79% at fifteen years followup (95% C.I.: 67–91%). Results: Excluding two revisions for septic loosening at 3 and 6 years, the survivorship with end point aseptic loosening was 84% at fifteen years years (95% C.I.: 73–95%). At review there were no additional radiological loosenings, although 7 acetabular reconstructions showed radiolucent lines in one or two zones. Conslusions: This acetabular bone impaction technique using large morselized bone chips (range 0.7–1.0 cm) and a cemented cup is a reliable reconstruction technique, even after a 15–20 years followup


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 333 - 333
1 Sep 2012
Essig J Nourissat C Asencio G
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The use of a total hip arthroplasty with alumina on alumina bearing couple should limit the risk of wear and secondary osteolysis. From June 1999 to December 2002, we have realised a continuous series of 265 ABGII cementless THA with Alumina bearing. The average age was 58 years (22–78 years). The main causes were osteoarthritis (81%) and osteonecrosis (13%). The operation was performed through a posterior standard approach. In all cases, an anatomic cementless ABG II stem and an acetabular cementless ABG II cup were implanted. The bearing couple was always Alumina Biolox Forte with a 28 mm femoral head in 99% of cases. To date, 12 patients died and 17 patients were lost to follow up (6.4%). 224 patients (232 hips) had a regular clinical and radiological follow-up. The mean follow up was 8.5 years (5–11 years). 9 patients were revised for septic loosening (4cases), femoral fracture (4 cases) and inveterate dislocation (1 case). There was no aseptic loosening. The overall survival rate at more than 10 years is 96.6%. We deplore 2 cases of postoperative dislocation. In this series, we did not observe any breakage of ceramic implant. The clinical and functional outcome is good and stable over time with an average PMA score at 17.6 and an average Harris score at 97.3. 16 patients reported at least one or more episode of abnormal noise “Squeaking” type (6%). It is most often a mild noise and it occurs in a static bending position. This noise disappeared with time in 10 cases. It never necessitated a prosthetic revision. The radiological control does not show any wear. There is no evidence of acetabular or femoral osteolysis. The radiological implant fixation according to the Engh and ARA criteria was good and stable in all cases. This series demonstrate that the implantation of an anatomic cementless HA arthroplasty with an alumina bearing in a young and active patient prevents the risk of wear and osteolysis and improves durability over time. The use of a 28 mm head does not increase the risk of instability and we did not observe failure of the ceramic implants


The Journal of Bone & Joint Surgery British Volume
Vol. 77-B, Issue 6 | Pages 847 - 852
1 Nov 1995
Massin P Duparc J

We retrospectively reviewed 56 patients (71 hips) treated by total replacement for severe disability after pelvic irradiation. Symptoms were associated with various radiological lesions due to irradiation, including atraumatic femoral-neck fracture, osteonecrosis of the femoral head or of the acetabulum, and radiation osteitis of the whole pelvis. From 1970 to 1982 we used standard cemented components in 49 hips and had a high rate of acetabular loosening (52%) at a mean follow-up of 69 months. This was probably due to the mechanical insufficiency of irradiated periacetabular bone. From 1983 to 1990 we routinely used acetabular reinforcement rings. The rate of aseptic acetabular loosening in 22 hips at a mean follow-up of 40 months was 19%, but there were two septic loosenings emphasising the risk of infection in these patients. When total replacement is required for an irradiated hip, we recommend reinforcement of the acetabulum using a metallic ring, but there is still an increased risk of infection and in difficult cases such as severe acetabular destruction or soft-tissue or vascular injuries, a Girdlestone procedure may be indicated


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 185 - 185
1 Mar 2008
Stulberg S Brander V Adams A Austin S Woods O
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Customization makes it possible to fulfill design requirements during MIS-THA procedures, and has helped define the parameters of fit and fill. This study describes the results of using customization techniques to develop a femoral implant for utilization. CT-based design criteria for femoral implants has-been developed and used for primary, cement-less, non-minimally invasive THA surgery. Over 1000 procedures performed with these devices have been associated with displaced femoral fractures, and have been revised for septic loosening. This study has 2 parts:. 20 implants were designed and implanted with CT-based criteria that utilized the identical fit and fill standards of the custom implants previously established, but had short (< 115 mm), tapered stems;. 20 patients underwent primary, cement-less THR wherein an off-the-shelf femoral implant system was determined to fulfill fit and fill requirements of custom implants. The stem of these implants was shortened (95–115 mm) and tapered. Implants in both groups were inserted using a single incision, posterior-lateral MIS approach. Patients were followed clinically and radiographically for six months. Immediate full weightbearing and use of a single cane were encouraged. The use of CT-based customization techniques is helpful for defining design criteria of femoral implants, but the instrumentation for inserting these implants must be adapted to the specific surgery. Customization also facilitates the design and evaluation of CAOS applications for inserting these MIS implants


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_I | Pages - 76
1 Mar 2002
Szabo A Rogan I
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We review our first 100 LCS rotating platform total knee arthroplasty (TKA) procedures. Done between July 1993 and December 1996, they are currently at four to seven year follow-up. The sample includes 100 TKAs done in 88 patients as unilateral or bilateral procedures. At operation the mean age of patients, 51% of whom were female and 49% male, was 67 years (47 to 84). The right side was replaced in 54% of cases and the left in 46%. Preoperative diagnoses included degenerative and post-traumatic osteoarthritis in 95 knees and rheumatoid arthritis in five. Two assessments are currently being carried out. They include the American Knee Society Clinical Rating Score, functional ability and radiographic evaluation of knee alignment and radiolucencies. Mean clinical and functional Knee Society ratings were 38 and 57 (sum 95 points) preoperatively and 88 and 84 (sum 172 points) postoperatively. Radiographs showed valgus alignment in 90 rays and varus alignment (1° to 7°) in 10. Limited areas of radiolucency were seen around three tibial components. Two cases have required revision, one for septic loosening and one to correct recurrent varus deformity


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 348 - 349
1 Jul 2008
Adeeb M Mersich I Neumann L Thomas M
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Background: Total elbow prostheses are broadly classified into linked and the unlinked categories. We have looked at long-term results of unlinked Kudo 5 total elbow replacement used in the treatment of patients with rheumatoid arthritis in 2 hospitals. Methods: 87 Kudo 5 Total elbow replacements in 70 patients with adult rheumatoid arthritis were performed at Wexham Park Hospital, Slough and City Hospital, Nottingham by 2 specialist elbow surgeons, the senior authors. 16 patients had died and 8 patients were lost to follow up. 62 elbow replacements in 46 patients were evaluated at a mean follow up of 79 months [29–137 months] using the Mayo Clinic Performance Index. Postoperative radiographs were also reviewed for loosening using standard anteroposterior and lateral films. Results: Preoperatively 6 had moderate pain and 56 had severe pain. Postoperatively the pain was rated as none or mild by 58 and moderate by 4. The average Mayo Elbow Score improved from 37 preoperatively to 86 postoperatively. The mean arc of flexion/extension improved from 60 to 99 degrees. There were 14 complications including ulnar neuropraxia, fracture, dislocation, triceps rupture and loosening. 4 cases were revised, 2 for aseptic and 2 for septic loosening. Postoperative radiographs showed 5 cases with loosening around the ulna component. Conclusions: The long-term results using the Kudo 5 elbow prosthesis in patients with rheumatoid arthritis are acceptable and comparable to other series reported of this implant. To date this is the largest series reported with the longest follow up using this implant


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_I | Pages 39 - 39
1 Jan 2003
Stanley D
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Although total elbow arthroplasty is undertaken in far smaller numbers than total hip and knee arthroplasty a recent review of the world literature indicated that aseptic loosening radiologically occurred in 17.2% whilst clinical loosening was present in 6.4%. In addition, infections were noted in 8.1%. With both aseptic and septic loosening bone loss can be a major problem and must be addressed if revision surgery is contemplated Options for treating bone loss include:. Revision with standard implant. Revision with customised implant. Revision with impaction bone grafting and standard or customised implant. Revision with allograft and standard or customised implant. When considering revision surgery it is essential to ascertain whether or not implant loosening is aseptic or septic. To this end screening blood tests including white blood count, ESR and CRP should be performed. A bone scan may also be helpful. In addition, it is my practice to perform an aspiration biopsy prior to revision surgery. A sample of fluid from the elbow joint is looked at microscopically and cultured for organism sensitivity. If infection is present surgery is undertaken as a two-stage procedure. The first stage involves removal of the implant and bone cement together with the insertion of antibiotic beads specially prepared with added antibiotics appropriate to the sensitivity of the infectiong organism. If infection is not present then a one-stage revision is performed


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 229 - 229
1 Mar 2004
Wirtz D Schuh A Rader C Gohlke F Carl H Zeiler G Forst R
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Aims: Prospective multi-center study to evaluate the mid-term results of 280 uncemented femoral stem revisions using the modular MRP-Titan system. Methods: 273 patients with 280 MRP-Titan systems, follow-up for a mean time of 3 years (1 to 8 years). Harris hip score for clinical evaluation, bony defect classification according to Paprosky [163 cases (58%) with type 2B, 2C and 3]. Results: Three aseptic loosenings (1%), three septic loosenings (1%), one additional re-revision because of periprosthetic fracture. Postoperative dislocations occurred in 23 cases (8%), 17 of these (6%) were managed by closed or open reposition without changing the implant. In 6 cases (2%) the antetorsion angle of the modular prosthesis neck was altered. Harris hip score: 38 points preoperatively, 85 points at the last follow-up postoperatively. In 18 cases (6.4%) radiolucient lines were seen, but with no progression and no migration of the stems. The overall survival-rate after 8 years of follow-up was 92%. Conclusions: The modular MRP-Titan system has proven to be valuable in quite problematic cases of hip revision arthroplasty with extensive femoral defects. The system allows intraoperative adaptation of implant length and antetorsion angle to the actual situation, a feature not provided by non-modular femoral revision implants


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_II | Pages 191 - 191
1 Feb 2004
Sdrenias C Mavrogenis A Tsaknis R Galanis K Christodoulou N
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The purpose of this study is to present the clinical and radiological evaluation of 632 resurfacing total knee arthroplasties of Foundation-Solution type, performed in 550 patients (437 women and 113 men), from 1994 to 2003. In the majority of cases (569 knees) the operation was performed because of degenerative osteoarthritis. Cement-free implantation was performed in 209, cemented in 117 and hybrid implantation in 306 procedures. We were able to retrospectively review 442 (80.4%) of the patients (498 knees), for a follow-up time of 6 months to 10 years. The Knee Insall Rating Scale was improved from 60 points (34–70) preoperatively, to 92 points (74–100) postoperatively. The range of flexion at the latest follow-up was between 75 to 130 degrees (mean 98 degrees). Extension lag more than 10 degrees was found in 3 patients (0.68%). The radiological evaluation was performed according to Knee Society Röentgenographic Evaluation and Scoring System. Partial periprothetic radiolucent lines (< 1mm) were observed in 35 knees (7%), with no statistical significant difference between the three groups and no progression during the follow-up. No further clinical and radiological evidence of mechanical failure and no significant loss of the mechanical axis were noticed. There was a case of fatal pulmonary embolism, and a case of peroneal nerve palsy that fully recovered. Three knees were revised as a result of septic loosening


The Journal of Bone & Joint Surgery British Volume
Vol. 91-B, Issue 4 | Pages 441 - 446
1 Apr 2009
Ornstein E Linder L Ranstam J Lewold S Eisler T Torper M

We identified 1305 femoral impaction bone grafting revisions using the Exeter stem performed between 1989 and 2002 in 30 hospitals throughout Sweden. There were 1188 patients with a mean age of 71 years (29 to 94) followed up for between five and 18 years. The participating departments reported 70 further revisions in total, of which 57 could also be identified on the Swedish National Arthroplasty Registry. Kaplan-Meier survivorship for all causes of failure was 94.0% (95% confidence interval (CI) 92 to 96) for women and 94.7% (95% CI, 92 to 96) for men at 15 years. Survivorship at 15 years for aseptic loosening was 99.1% (95% CI 98.4 to 99.5), for infection 98.6% (95% CI 97.6 to 99.2), for subsidence 99.0% (95% CI 98.2 to 99.4) and for fracture 98.7% (95% CI 97.9 to 99.2). Statistically significant predictors of failure were the year in which revision was conducted (p < 0.001). The number of previous revisions was slightly above the level of signifance (p = 0.056). Age, gender, the length of the stem and previous septic loosening were not predictors of failure (p = 0.213, p = 0.399, p = 0.337, p = 0.687, respectively). The difference in survivorship between high- and low-volume departments was only 3% at ten years. We conclude that impaction bone grafting with the Exeter stem has an excellent long-term survivorship following revision arthroplasty. The technique of impaction grafting appears to be reliable, can be learned rapidly and produces a predictably low incidence of aseptic loosening


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 355 - 355
1 Mar 2004
Kumar B Ali S
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Aims: To report medium term results of Beuchal Pappas total ankle replacement carried out at Corbett hospital. Methods: We report a series of 15 patients who underwent this procedure at the Corbett hospital in Dudley between February 95 and March 01. One patient died of an unrelated cause and 14 were followed for an average of 4 years. All patients received the New Jersey total ankle replacement performed by one senior consultant orthopaedic surgeon (SA). The patients were invited to attend a special follow up clinic for clinical and radiological review. The Kitioka ankle scoring system was used to assess outcome. Results: The average age was 64 years. There were 8 women and 6 men. The preoperative diagnosis was advanced post-traumatic arthritis in all patients. Two underwent revision of tibial component- one at 3 years post operative for septic loosening, and the other at 2 years post operative for aseptic loosening. One patient required open washout 7 months post operative for deep infection. The average ankle score in the group was 79. All patients replied in the afþr-mative when asked if they would undergo the operation again. Conclusions: We feel that in carefully selected patients ankle replacement gives satisfactory outcome and can be safely performed in a district general hospital setting. Careful preoperative counselling regarding risks of loosening and infection is essential


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_II | Pages 155 - 155
1 Feb 2004
Dermon A Êolovos Í Trabalis A Chelepidis K Tilkeridis C
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Surgeon who used the uncemented cup must choose between two kids of cups: the porous coated (press fit) and the threaded. Many authors present several discouraging results. Nevertheless satisfactory results have also been obtained using threaded cups and the explanation lays in the design the alloy and the surface characteristics of the acetabular component. We describe the clinical and radiological outcome of 93 THA in 81 patients using a screw-in cup (Link- type) performed between 1994–2000. Our follow-up time was and the average age of the patients was 68y,all were primary THA(78 OIA,15 sub-capital fractures).Clinical evaluation was perfomed using the Merle d’ Aubigne hip score. Results: We had good results in 90,3%. Migtation of 2mm of the treaded ring was present in 9 (nine) THA. Although only one has been revised up to now the future of the others remain uncertain. There was no revision of the femoral stem but we had one septic loosening. Conclusion: Our findings suggest that long-term fixation of a treaded cup in primary T’HA was satisfactory if there aren’t present any migration factors like osteoporosis whatever the etiology (in these cases we must put an over-size cup) and a wrong primary position. We believe also that the design of the Link-type treaded cup with this depth-extension space of the treads and the absence of the bottom hole is related with our good results


The Journal of Bone & Joint Surgery British Volume
Vol. 85-B, Issue 4 | Pages 510 - 516
1 May 2003
Langlais F Lambotte JC Collin P Langlois F Fontaine JW Thomazeau H

We used a trochanteric slide osteotomy (TSO) in 94 consecutive revision total hip arthroplasties (90 with replacement of both the cup and stem). This technique proved to be adequate for removing the components, with few complications (two minor fractures), and for implanting acetabular allografts (18%) and reinforcement devices (23%). Trochanteric union was obtained in most patients (96%), even in those with septic loosening (18/19), major femoral osteolysis (32/32), or previous trochanteric osteotomy (17/18). TSO is versatile, since it can be extended by a femoral flap (four cases) or a distal femoral window (eight cases). Despite significant bone loss, in 24% of the femora and 57% of the acetabula, favourable midterm results were achieved and only six reoperations were required, including two for trochanteric nonunion and two for loosening. It leaves the lateral femoral cortex intact so that a stem longer than 200 mm was needed in only 25% of patients. This is a considerable advantage compared with the extended trochanteric osteotomy in which the long lateral flap (12 to 14 cm) requires an average length of stem of 220 mm beyond the calcar. TSO provides an approach similar in size to the standard trochanteric osteotomy but with a rate of nonunion of 4% versus 15%. It reduces the risk of difficulties with removal of the stem, and removes the need for routine distal anchoring of long revision stems. The limited distal femoral compromise is very important in patients with a long life expectancy


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 216 - 216
1 May 2006
Adeeb M Mersich I Neumann L Thomas M
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Background: Total elbow prostheses are broadly classified into linked and the unlinked categories. We have looked at long-term results of unlinked Kudo 5 total elbow replacement used in the treatment of patients with rheumatoid arthritis in 2 hospitals. Methods: 87 Kudo 5 Total elbow replacements in 70 patients with adult rheumatoid arthritis were performed at Wexham Park Hospital, Slough and City Hospital, Nottingham by 2 specialist elbow surgeons, the senior authors. 16 patients had died and 8 patients were lost to follow up. 62 elbow replacements in 46 patients were evaluated at a mean follow up of 79 months [29–137 months] using the Mayo Clinic Performance Index. Postoperative radiographs were also reviewed for loosening using standard anteroposterior and lateral films. Results: Preoperatively 6 had moderate pain and 56 had severe pain. Postoperatively the pain was rated as none or mild by 58 and moderate by 4. The average Mayo Elbow Score improved from 37 preoperatively to 86 postoperatively. The mean arc of flexion/extension improved from 60 to 99 degrees. There were 14 complications including ulnar neuropraxia, fracture, dislocation, triceps rupture and loosening. 4 cases were revised, 2 for aseptic and 2 for septic loosening. Postoperative radiographs showed 5 cases with loosening around the ulna component. Conclusions: The long-term results using the Kudo 5 elbow prosthesis in patients with rheumatoid arthritis are acceptable and comparable to other series reported of this implant. To date this is the largest series reported with the longest follow up using this implant


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 26 - 27
1 Mar 2006
Perka C Katterle H Drahn T Matziolis G
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Introduction: The objective of the study was to test the hypothesis that revision total hip arthoplasty in cases with extensive acetabular bone defects performed with a newly developed, conical, titanium, ribbed shaft socket designed for cementless press-fit into the dorsocranial ilium would not demonstrate inferior outcomes using literature controls. Methods: 38 consecutive hips had an acetabular revision with a pedestal cup. All of the patients had a type IIIa or IIIb defect according the Paprosky-classification. There was an average follow-up of 4.2 years, with a range of 3 to 6 years. Two patients died, one patient was lost to follow-up. All patients were evaluated radiographically, by CT-Scan and clinically. Results: At the time of follow-up, 32 (91.4%) cups were stable. Aseptic loosenings occured in one case, septic loosenings occured in 2 cases. The average Harris Hip Score improved from 43 points (range: 16–78 points) preoperatively to 82 points (range 56–98 points) postoperatively. Complications included four dislocations without recurrency. The guide instrument facilitates correct anchorage in the dorsal ilium in all cases. Conclusion: The presented findings show the short-term efficancy of the procedure with respect to implant fixation and clinical results in large acetabular defects, but longer follow-ups and a larger number of patients are needed before the durability of this reconstructive technique can be assessed. The implant allows restoration of the correct centre of rotation, equalization of leg length and optimization of the strength of the hip abductors. Our results should be considered encouraging


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 541 - 541
1 Nov 2011
Rollier J Philippot R Vidalain J
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Purpose of the study: The pertinence of locking for major femoral revision remains a controversial issue. We conducted a retrospective multicentric study to assess the benefit and potential clinical and radiographic complications after using a long locked stem entirely coated with hydroxyapatite. Material and methods: Our series included 77 patients (42 women, 35 men), mean age 71 years (range 34–90) reviewed at minimum one year. A modular implant was used; the long curved stem allowed total integration. Screws guaranteed distal locking. There were 71 revision THA on trochanteric-shaft fractures, three shaft nonunions, 34 aseptic loosenings, 9 septic loosening, 21 fractures on prosthesis, 6 implant failures and one instability. Seventy percent of patients had stage 3 and 4 bone lesions. Mean follow-up was 60 months. Results: At last follow-up, 90% of patients were satisfied or very satisfied. The mean Harris function score improved from 32 to 83 and the PMA from 7 to 15. Sixty-four patients were pain free and 22% had pain solely under stress. There were 15 bone complications: dislocation (n=3), early infection (n=3 including 2 recurrences), implant failure (n=2), secondary femur fracture (n=5). Stem survival was 94% at nine years. Radiographically, total stem stability was noted in 73 patients (95%); instability was noted in four cases of fracture. Undeniable metaphyseal improvement was noted in 20% of cases, more modest improvement in 32%; the situation was considered unchanged in 31%. Locking was successful in all cases; cortical bone in contact with the locking screw was unchanged in 59 cases, slightly thickened in 16, including one case with a context of septic recurrence. The locking was dismantled in two cases (one empirically and one for pain), but the stem remained stable. Discussion: Major damage to the femur can compromise stabilisation of the proximal or diaphyseal implants. Distal locking contributes to the initial mechanical stability, indispensable for secondary osteointegration of the implant. However, with total hydroxyapatite coating, rapid fixation in healthy zones is also crucial. Reconstruction of metaphyseal bone is not easy to quantify, but the absence of bone absorption is noteworthy


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 508 - 508
1 Nov 2011
Manopoulos P Havet É Mertl P Parizon P Lardanchet J De Lestang M
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Purpose of the study: Restrained implants with intrinsic stability guaranteed by a large central stem have been developed for revision knee arthroplasty, irrespective of the underlying cause. Successful restraint implies excellent fixation of the prosthetic implants which can be obtained using press-fit centromedullary stems. The purpose of this work was to assess the long-term results of this mode of fixation in this indication and to search for clinical correlations with potential radiological images around the stems. Material and methods: We report 46 cases of Sigma. ®. PFC TC3 revision total knee prostheses reviewed retrospectively at two years with a mean follow-up of eight years. Mean age at surgery was 68 years. Revision was indicated for aseptic loosening (n=24) and septic loosening (n=22). The knee society criteria were used for the clinical evaluation. Radiographic measurements were made semiautomatically with the Imagika. ®. software. Results: The mean clinical score improved from 42 points preoperatively to 84.7 at two years and 83.7 at last follow-up. Outcome was excellent (n=30), good (n=7), fair (n=1) and poor (n=1). The mean function score improved from 34.3 preoperatively to 69.1 at two years and 64.2 at last follow-up. Radiographic alignment was correct in all cases. The press-fit effect was observed for 63% of the femoral implants and 76% for the tibial implants. Around the stems, 57% of the implants exhibited condensation lines and 23% lucent lines measuring less than 2 mm. There was no relation between radiological findings and the clinical or functional scores. There were two failures, one for frontal instability at six years and the other for aseptic loosening at eight years. Excepting these two cases, there was one case of femoral implant migration with no clinical expression. For all other patients, the radiographic image remained unchanged between the two year check-up and the final follow-up. Discussion: Thee presence of lucent lines or condensation lines is well known for this type of implant with long centromedullary stems. Nevertheless, this is the first clinical series evaluating the clinical impact of these radiographic images. In our opinion, these images are related to the relative mobility of these implants which should be checked regularly, although no long-term clinical expression occurs. For us, this type of implant enables good function and long-term stability


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 258 - 258
1 May 2009
Malone A Sanchez-Sotelo J Adams R Morrey B
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The purpose of this study is to report our experience with revision of total elbow arthroplasty by exchange cementation. Between 1982 and 2004 at our institution, forty six elbows were treated with exchange cementation of a total elbow arthroplasty into the existing cement mantle or debrided bone interface, without the use of an osteotomy, bone graft or prosthetic augmentation. Indications for the procedure were aseptic loosening (17), second stage after septic loosening (14), instability (7), prosthetic fracture (4), periprosthetic fracture (2), failed hemiarthroplasty (1) and ulnar component wear (1). Both components were exchanged in 18 elbows, the humerus alone in 25 and the ulna in 3. Mean follow up was 90.5 months (10 to 266 months);18 patients had died with the prosthesis in situ. Complications were noted in 22 elbows; periprosthetic fracture of ulna (6) and humerus (2), humeral component fracture (1), aseptic loosening (4), non-union (1), heterotrophic ossification (2), soft tissue contracture (2) and soft tissue failure (2), delayed wound healing (1) and bushing failure (1). Reoperation was required in 10 elbows for revision of both components (2), ulna (3), humerus (1), bushing revision (2), soft tissue debridement (1) and soft tissue repair (1). There were no septic recurrences in previously infected elbows; however the reoperation rate in this group was 29% versus 19% after re-cementation for other causes. Revision of total elbow arthroplasty by exchange cementation is a reasonable treatment for those elbows with adequate bone stock for secure prosthetic fixation; however careful consideration should be given to augmentation of the ulna due to the high rate of periprosthetic fracture in this series. Re-cementation following débridement for infection is effective despite having a higher rate of revision operation compared to re-cementation in the aseptic elbow


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 282 - 282
1 Sep 2005
Basson D
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Infection after total joint arthroplasty can present a diagnostic challenge. No preoperative tests are consistently 100% sensitive and specific, so the diagnosis of infection depends on the surgeon’s judgment with respect to the clinical presentation and examination and interpretation of the results of investigations. The consequences of misdiagnosis are severe. Reimplantation of a prosthesis into an infected host bed is likely to result in persistent infection. Preoperative investigations include haematological screening tests (white blood cell count, ESR, and C-reactive protein), joint aspiration and arthrography, radiography, and radionuclide imaging studies. Intraoperative investigations include analysis of synovial fluid, gram-staining of tissue that appears inflamed, histological evaluation of frozen sections of inflamed tissue, and culture of periprosthetic tissue. The exclusion of infection as a cause of failure is imperative to determine the management of patients who need revision total joint replacement. The key to making the correct diagnosis is using not a single investigation but rather a correct combination of investigations. From 2001 to 2004 we studied 46 patients referred from various centres with prosthesis loosening. The patients had technetium and gallium scintigraphy. In 32 patients, scintigraphic studies suggested septic loosening. Of these, 21 patients also had aspirations, three intraoperative cultures and 11 both aspirations and intraoperative cultures. The remaining 11 patients had aseptic loosening and were used as a control group. In only 10 patients was sepsis proved by aspiration or culture. Our results, which show that scintigraphy has a dismal positive predictive value as a screening test and a good negative predictive value, concur with the current literature


The Journal of Bone & Joint Surgery British Volume
Vol. 82-B, Issue 8 | Pages 1151 - 1155
1 Nov 2000
Radl R Aigner C Hungerford M Pascher A Windhager R

We performed a retrospective analysis of the clinical and radiological outcomes of total hip replacement using an uncemented femoral component proximally coated with hydroxyapatite. Of 136 patients, 118 who had undergone 124 primary total hip replacements were available for study. Their mean age was 66.5 years (19 to 90) and the mean follow-up was 5.6 years (4.25 to 7.25). At the final follow-up the mean Harris hip score was 92 (47.7 to 100). Periprosthetic femoral fractures, which occurred in seven patients (5.6%), were treated by osteosynthesis in six and conservatively in one. We had to revise five femoral components, one because of aseptic loosening, one because of septic loosening and three because of periprosthetic fracture. At the final follow-up there were definite signs of aseptic loosening in two patients. Radiologically, proximal femoral bone loss in Gruen zones I and VI was evident in 96.8% of hips, while bone hypertrophy in zones III and V was seen in 64.7%. In 24 hips (20.2%) the mean subsidence of the stem was 3.7 mm which occurred within the first 12 postoperative weeks. This indicated poor initial stability, which might have been aggravated by early weight-bearing. The high rate of failure in our study suggests that proximal femoral bone loss affects the long-term survival of the replacement


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 51 - 51
1 Mar 2009
Grappiolo G Burastero G Moraca G Camera A Santoro G Gruen T Spotorno L
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Background: This report presents the long term (over 20 years) experience with the use of a grit-blasted, press-fit femoral prosthesis. Methods: The first 300 consecutive primary THA procedures using a collarless, three-dimensional tapered, straight, titanium alloy stem with a grit-blasted surface (performed in 299 patients) were evaluated up to twentytwo years. A cementless all-polyethylene socket in 80 percent of the cases, were used. Radiographic evaluation, performed by an independent observer using a zonal analysis method, included assessment of component migration, Engh’s implant-bone femoral fixation score, implant-bone demarcations, and periprosthetic osteolysis. The average duration of long-term radiographic follow-up was 12.6 years (range; 10 to 16 years). Results: At last examination only five hips were lost to follow-up and 84 patients were deceased. The femoral revision rate was 7 percent (two hips for aseptic loosening, five hips for septic loosening, and twelve hips with osseointegrated stems for severe progressive femoral osteolysis) and the acetabular revision rate was 28% (revised for either socket migration or progressive peri-acetabular osteolysis or both). Survivorship, based on any revision (femoral or acetabular) was 89% at ten years and 65% at twenty years; survivorship of the femoral component was 95% at ten years and 89% at twenty years. The incidence of femoral periprosthetic osteolysis, was 47%, with 5% of distal endosteal osteolysis. Radiographic femoral implant-bone fixation was stable, bone-ongrowth in 97%; stable, fibrous-fixation in 1%. Conclusions: The grit-blasted, press-fit, collarless, tapered femoral component continued to perform well clinically and radiographically up to twenty years of follow-up despite the challenging environment of peri-prosthetic osteolysis associated with the acetabular component design. This implant is still in use virtually without design modifications. This study demonstrates the durability of the results of the grit-blasted femoral component and indicates that such an implant offers a viable alternative for fixation without bone cement


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 173 - 174
1 Mar 2009
Lusser R Luem M Ochsner P
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Introduction: The Wagner SL Stem is a well established implant to bridge proximal femoral defects in hip revision surgery. The tapered shape offers the possibility of press-fit anchorage distal to the bone defect. There are missing long term results with absolute follow-up over ten years. The goal of the study was to observe the subsidence and the restoration of the proximal bony stock within ten years. Patients and Methods: From 1988 until 2005 198 Wagner Stems were implanted in our hospital. 50% of the indications were due to aseptic loosening, 25 % due to septic loosening and 10% due to periprosthetic fracture and 15% other indications. Clinical function was measured with an adapted Harris Hip Score; subsidence was measured in the way that was previously described by Callaghan. The bony restoration was controlled with Böhm’s technique. The length and the thickness of the area of integration were measured in mm on the ap radiographs of the femur. Results: The over all survival of the 198 Wagner stems after 17 years was 87%, for aseptic loosening. There were 57 implanted stems with ≥10 years follow-up. 31 of the patients died before the ten year control, four stems had to be exchanged because of aseptic loosening, three patients referred the clinical control so that a total number of 19 stems could be followed for at least 10 years. In two of those 19 stems there was significant subsidence (12 and 33mm), the subsidence occurred within the first year after implantation. The area of integration showed no change of length or thickness. The bony restoration was good or excellent in 70%. The adapted Harris Hip Score declined only little from 80 postoperatively to 75 after ten years. Conclusion: No significant subsidence after Osteointegration occurred. The principle of the tapered stem is as good that the Wagner SL Stem can be widely indicated


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 111 - 112
1 Mar 2010
Lee S Ahn Y Chung S
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Extensive bone deficiencies in proximal femur remains a significant challenge in hip surgery. In such a situation, one alternative is to use a proximal femoral allograft-prosthesis composite (APC) to restore the mechanical integrity and bone stock. The current study was performed to analyze the results of APC in the treatment of femoral bone deficiency. From January 1996 to June 2006, 12 patients who received 15 APC (3 of them received repeated APC), were followed for a mean of 4.2 years (range 2.0 to 9.8 years) by one surgeon. 5 were males and 7 were females and the mean age of the patients was 60.9 years (range 32 to 84 years). 6 patients were diagnosed with septic loosening, 5 were with aseptic loosening, 4 were with re-revision arthroplasty, and 1 was with limb salvage procedure due to malignancy and all were treated with fresh-frozen allograft. The surgical technique was used to cement the femoral component into the allograft but not into the host bone except 1 case. The average Harris hip score improved from 21.8, preoperatively, to 83.2, the latest follow-up, and the all stems showed good stability except 3 cases of aseptic loosening. These 3 cases went through a repeated operation with another APC after mean 83.7 months (51,92,108 months) and their results showed good stability. 11 APC had a good junctional union. One case was showed junctional nonunion that needed onlay graft at 3.3 years after APC. There were no infections (or septic loosening), dislocations and allogragt fractures (except one great trochanter avulsion fracture, neither clinical symptoms nor went a surgical treatment). This study demonstrated that the use of APC for extensive proximal femoral bone deficiencies showed a clinically, functionally and radiologically good results. Therefore it is considered as a good options


Bone & Joint Research
Vol. 11, Issue 3 | Pages 143 - 151
1 Mar 2022
Goetz J Keyssner V Hanses F Greimel F Leiß F Schwarz T Springorum H Grifka J Schaumburger J

Aims

Periprosthetic joint infections (PJIs) are rare, but represent a great burden for the patient. In addition, the incidence of methicillin-resistant Staphylococcus aureus (MRSA) is increasing. The aim of this rat experiment was therefore to compare the antibiotics commonly used in the treatment of PJIs caused by MRSA.

Methods

For this purpose, sterilized steel implants were implanted into the femur of 77 rats. The metal devices were inoculated with suspensions of two different MRSA strains. The animals were divided into groups and treated with vancomycin, linezolid, cotrimoxazole, or rifampin as monotherapy, or with combination of antibiotics over a period of 14 days. After a two-day antibiotic-free interval, the implant was explanted, and bone, muscle, and periarticular tissue were microbiologically analyzed.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_VIII | Pages 17 - 17
1 Mar 2012
Busch VJ Klarenbeek RL Gardeniers JWM Schreurs BW
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Introduction. Total hip arthroplasties (THAs) in young patients are associated with high failure rates. We always use cemented total hip implants, however, in cases with acetabular bone stock loss we perform bone impaction grafting. Our purpose was to evaluate the outcome of 69 consecutive primary cemented total hips in patients younger than 30 years followed between 2 to 18 years. Methods. Between 1988 and 2004, 69 consecutive primary cemented THAs (mainly Exeters) were performed in 48 patients (32 women, 16 men) younger than thirty years. Average age at time of operation was 25 years (range, 16 to 29 years). Twenty-nine hips (42%) underwent acetabular bone impaction grafting because of acetabular bone loss. Mean follow-up was 10 years (range, 2 to 18 years). Revisions were determined, Harris Hip Score (HHS), and Oxford Hip Questionnaire Score (OHQS) were obtained and radiographs were analyzed. Survival was calculated using the Kaplan-Meier method. Results. No patients were lost to follow-up, but 3 patients (4 hips) died during follow-up, none of whom had underwent revision. Eight revisions were performed: 3 septic loosenings (6, 7, and 8 years post-operative) and 5 aseptic cup loosenings (2, 3, 4, 5, and 9 years post-operative). No stems were loose. The average HHS and OHQS at follow-up were 89 points (range, 55 to 100 points) and 19 points (range, 12 to 42 points), respectively. Using Kaplan-Meier analysis, the cumulative survival with revision for any reason as end point was 83% (95% CI, 69 - 92%) at 10 years. Excluding the infections, the survival rate was 90% (95% CI, 77 - 96%) with revision for aseptic loosening. The outcome of the patients who underwent acetabular bone impaction grafting was comparable to the primary cemented hips with a survival of 89% (95% CI, 62 - 97%) with revision for any reason as an end point. Excluding the infections, the survival rate was 95% (95% confidence interval, 72 - 99%) at ten years with revision for aseptic loosening as the end point. Conclusion. Primary cemented total hip arthroplasties in very young patients show satisfactory medium-term results, however, in cases with acetabular bone stock loss, a reconstruction with bone impaction grafting is advisable


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 291 - 291
1 Sep 2012
Iotov A Ivanov V Tzachev N Baltov A Liliyanov D Kraevsky P Zlatev B Kostov D
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INTRODUCTION. Management of neglected residually displaced acetabular fractures is a big challenge. ORIF is often doomed to failure so a primary total hip replacement is usually kept in mind as a method of choice. However THR is a technically difficult and results are quiet unpredictable. OBJECTIVE. To present our experience with THR in maltreated grossly displaced acetabular fractures and to discuss operative technique and prognostic factors in that complicated surgery. MATERIAL. THR was applied in 14 patients (11 males and 3 females, mean age 51 years) with at least three-months old and significantly displaced acetabular fractures. In 12 cases preceding treatment was conservative, and in 2 it was operative. Fracture nonunion was recognized in 5 cases, old hip dislocation in 4 and protusion in 3. Large interfragmentary gaps and local bone defect were detected in almost all cases. METHOD. THR was performed 3–31 months after injury. Extensile iliofemoral or Y-shaped approach with trochanteric osteothomy was used in most cases. Depending of particular situation a variety of techniques were applied to provide adequate bone stock for the cup, such as an approximate ORIF, periacetabular osteotomy, structural or morcelised bone grafting. Reinforcement ring was used in 6 cases. The cup fixation was cemented in 12 procedures and uncemented in 2. Cemented stem was introduced in 10 cases and uncemented in 4. Preoperative selective embolisation of superior gluteal artery was carried out in 1 patient. RESULTS. The operative duration was 3–7 hours and blood loss was 850–2200 ml. The only intraoperative accidentwas jatrogenic lesion of superior gluteal artery required embolisation. The follow up was a 16–94 months. Average postoperative Harris Hip Score was 78, compared with 54 before surgery (P<0.01). There was 2 aceptic and 1 septic loosenings with subsequent revisions (21.4%). In 2 cases sight asymptomatic migration of the cap was noted. DISCUSSION. The most difficult but most important stage of operation is a creating of sufficiently stable bone stock for the acetabular cap, impeded by by fragment displacement, nonunion or prolonged hip dislocation. If nonuion the achievement of bone healing is essential. Any instability should be overcomed by stable osteosynthesis. The gaps should be filled by ORIF or bone grafting. We consider cemented fixation possibly with reinforcement ring as a most secure way to provide strong cup anchorage. Uncemented pess-fit cup may be used in cases with lesser initial displacement. In spite of all late results are considerable worse than in conventional hip replacement. CONCLUSION. THR after neglected acetabular fractures is a challenging and demanding procedure. Successful outcome may be only expected if a solid bone stock is made using various surgical techniques


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 334 - 334
1 Mar 2004
Doets H Olsthoorn P Schmotzer H
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Aims: To evaluate the results of a novel modular press-þt acetabular cup in primary total hip arthroplasty (THA) for osteoarthrosis (OA) and inßammatory arthritis (IA). Methods: From February 1996 to June 1999 in 324 patients (249 women, 75 men) 355 THA using a novel cup has been carried out. The shell is non-hemispherical on cross-section and has a hydroxyapatite coating on porous titanium for osseointegration. Diagnosis was: osteoarthrosis (OA) 236, developmental dysplasia (DDH) 21, post-traumatic arthrosis 27, avascular necrosis 6, IA 65 Ð mainly rheumatoid arthritis (RA). Average age at operation was 65.8 years. The patients were studied prospectively using Harris Hip Score (HHS), by measuring any radiolucency around the cup and by looking for signs of migration. Results: Median follow-up was 4.5 years. At follow-up, 21 patients had deceased. Revision for deep infection was carried out in 5 hips (3 low-grade infections). No septic loosening occurred with low-grade infection. Recurrent dislocations required revision of 1 cup and exchange of 2 inserts. Only 1 cup in a RA patient with severe superior bone loss became unstable after a fall 4 months postoperatively. Survival with aseptic loosening of the cup as endpoint was 1 in OA and 0.98 in IA. In all 290 patients with 318 THA in follow-up the cup was functioning well, both clinically and radiographically. HHS increased from 44.5 to 90.3. Conclusion: Press-þt þxation using a modern acetabular component is an excellent treatment option in primary total hip arthroplasty for all diagnostic groups


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 275 - 275
1 Mar 2004
Berli B Elke R Morscher E
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Introduction: The operation method selected for acetabular revisions depends on the type of deþciency; Type 1: contained cavitary; the acetabular rim is preserved and thus supportive. Type 2: non-contained deþciencies; the acetabular rim and the peripheral zones are non- supportive defects. In non-contained, rim non-supportive defects acetabular reinforcement rings are used as a rule. Material and methods: Between July 1988 and December 1997 465 acetabular revisions with 229 Reinforcement Rings and 236 Press- Fit Cups (4 bilaterally) were performed. A 7.5 (5.0–10.8) year clinical and radiological follow-up of the Press-Fit Cup inserted in 130 women and 102 men was effected. Mean age at revisions surgery was 70 in women and 73 in men. 39 patients (17%) died without needing a re-revision, and 17 (7%) could only be interviewed by phone. One patient was lost to follow-up. Of the remaining 175 patients (75%) with 179 hips (76%) were available for complete evaluation. Results: The clinical results (according to Merle dñAubignŽ) was excellent and good in 82% 143 pts), moderate in 17% (30 pts) and poor in 1% (2 pts). 22 (9%) reinterventions were noted during the observation period: 12 for dislocations, 5 for aseptic stem loosening, 1 for septic loosening, 2 for secondary periprosthetic fractures and 2 for removal of heterotopic ossiþcations. Conclusions: No Press-Fit Cup had to be re-revised for aseptic loosening. Reconstruction for contained, rim supportive defects with the Press-Fit Cup provides excellent results, comparable to those of primary arthroplasties


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 198 - 198
1 May 2011
Anagnostakos K Jung J Kelm J Schmitt E Schmid N
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There exist 4 methods for femoral fixation of hip spacers:. a simple insertion,. a partial/full cementation,. the “glove”-technique, and,. a cement bridge in case of large osseous defects of the proximal femur. To our knowledge, it is still unknown which of these methods provides the best stability. Between 01.01.1999–31.12.2008, 84 hip spacer implantations in 78 patients have been performed in our department. All patients have been treated with the same kind of spacer. 24 spacers have been fixed with the “glove”-technique, 18 with a partial cementation onto the proximal femur, 21 with a simple insertion, and 4 with a cement bridge. In 17 cases with an isolated septic loosening of the acetabular cup, only a spacer head has been placed onto the well-fixed prosthesis stem. The overall dislocation rate between stages was 21.4 % (18/84). The lowest dislocation rate was observed in the “spacer head” group with 5.8 % (1/17), followed by the “glove”-technique with 12.5 % of the cases (3/24). In the “partial cementation” group the dislocation rate was 22.2 % (4/18), whereas in the “insertion” group spacer dislocations occurred in 9 out of 21 cases (42.8 %). In the latter group, in 3 cases the spacer rotated primarily in the femur and dislocated subsequently out from the acetabulum. From the 4 patients having been treated with a cement bridge, 2 patients suffered from a spacer dislocation. From these 18 cases, 15 patients have been treated conservatively by reduction and immobilization in a hip orthesis during the remaining time between stages. The other three cases underwent further surgical procedures; in one case (combined spacer dislocation and -fracture), the spacer had been exchanged, whereas the other two cases had been treated by resection arthroplasty after recurrent spacer dislocations and unsuccessful conservative treatment. The “glove”-technique seems to be the most effective method for femoral fixation fixation of hip spacers regarding the prevention of dislocations between stages. Further advantages of this technique include a safe and easy spacer explantation in one piece without cement debris at the second stage


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 475 - 475
1 Sep 2009
Pignatti G Trisolino G Rani N Dallari D Giunti A
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The use of monoblock tapered stems has shown very good results in hip revision surgery, particularly in case of severe proximal femur bone deficiency. However a too valgus neck, a short offset, may result in a high risk of dislocation. In addiction monoblock stems make the control of limb length difficult, and potentially increase the risk of subsidence or intraoperative fracture. Different types of modular tapered stems with distal fixation have been developed to allow a more user-friendly restoration of limb-lenght discrepancy and an indipendent proximal control of offset and anti-retroversion. We assessed 64 hip revisions performed on 63 patients (mean age 62 years). Indication for treatment was: aseptic loosening (42 cases) septic loosening (18 cases) and periprosthetic fracture (4 cases). According to Paprosky classification, femoral defects were staged as type I (2 cases), type II (20 cases), type IIIA (25 cases) and type IIIB (13 cases); periprosthetic fractures were all type B2 according to the Vancouver classification. In all cases we used a Restoration® Modular (Striker, Orthopaedics) cone-conical uncemented stem implanted by a lateral approach, with a trans-femoral osteotomy in 19 cases. A preventive cerclage cable was used in 10 patients in case of very thin cortex. We used the minimum size stem in most of the cases. Mean follow-up was 20 months (range 6–36). Short-term complications included hip dislocation (1 case), recurrent infection (1 case), stem subsidence > 5 mm (1 case). Mean Harris Hip Score improved from 43 to 81.9 (t test p< 0.0005), while limb lenght discrepancy improved in 97% of cases with symmetry in 76%. The use of modular revision stems is an effective alternative in hip revision surgery that ensures good primary stability, while modularity enables the implant to be tailored to the patient, allowing restoration of the limb length and correct muscular balancing