We aim to analyze the role of patient-related factors on the yield of progenitor cells in the bone marrow aspiration concentrate (BMAC). We performed a retrospective analysis of patients who underwent autologous iliac crest-based BMAC therapy between Jan 2021–and June 2021. Patient-related factors such as age, sex, and comorbidities and procedure variables such as aspirate volume were analyzed. The yield of the bone marrow aspiration concentrate was assessed with MNC count and CFU assay from the aspirates. 63 patients with a mean age of 51.33±17.98 years were included in the study. There were 31 males and 32 females in the study population with a mean volume of 67.16±17.312 ml being aspirated from the iliac crest for the preparation of BMAC. The final aspirate had a mean MNC count of 20.16±15.73×10^6 cells which yielded a mean of 11±12 CFUs. We noted significant negative correlation between age and MNC count (r=minus;0.671, p<0.001) and CFUs (r=minus;0.688, p<0.001). We did not find the sex to have any significant role in MNC (p=0.082) count or CFUs formed (p=0.348). The presence of comorbidity significantly reduced the MNC count (p=0.003) and CFUs formed (p=0.005). The aspiration volume significantly negatively correlated with MNC count (r=minus;0.731, p<0.001) and CFUs (r=minus;0.618, p<0.001). The MNC count and CFUs formed from the BMAC depend on the patient-specific subjective variables such as age, and comorbid conditions present in them. Sex and volume of aspiration do not alter the MNC count or the CFUs formed from BMAC

Mechanical failure of spine posterior fixation in the lumbar region Is suspected to occur more frequently when the sagittal balance is not properly restored. While failures at the proximal extremity have been studied in the literature, the lumbar distal junctional pathology has received less attention. The aim of this work was to investigate if the spinopelvic parameters, which characterize the sagittal balance, could predict the mechanical failure of the posterior fixation in the distal lumbar region.

All the spine surgeries performed in 2017-2019 at Rizzoli Institute were retrospectively analysed to extract all cases of lumbar distal junctional pathology. All the revision surgeries performed due to the pedicle screws pull-out, or the breakage of rods or screws, or the vertebral fracture, or the degenerative disc disease, in the distal extremity, were included in the junctional (JUNCT) group. A total of 83 cases were identified as JUNCT group. All the 241 fixation surgeries which to date have not failed were included in the control (CONTROL) group. Clinical data were extracted from both groups, and the main spinopelvic parameters were assessed from sagittal standing preoperative (pre-op) and postoperative (post-op) radiographs with the software Surgimap (Nemaris). In particular, pelvic incidence (PI), sagittal vertical axis (SVA), pelvic tilt (PT), T1 pelvic angle (TPA), sacral slope (SS) and lumbar lordosis (LL) have been measured.

In JUNCT, the main failure cause was the screws pull-out (45%). Spine fixation with 7 or more levels were the most common in JUNCT (52%) in contrast to CONTROL (14%). In CONTROL, PT, TPA, SS and PI-LL were inside the recommended ranges of good sagittal balance. For these parameters, statistically significant differences were observed between pre-op and post-op (p<0.0001, p=0.01, p<0.0001, p=0.004, respectively, Wilcoxon test). In JUNCT, the spinopelvic parameters were out of the ranges of the good sagittal balance and the worsening of the balance was confirmed by the increase in PT, TPA, SVA, PI-LL and by the decrease of LL (p=0.002, p=0.003, p<0.0001, p=0.001, p=0.001, respectively, paired t-test) before the revision surgery. TPA (p=0.003, Kolmogorov-Smirnov test) and SS (p=0.03, unpaired t-test) differed significantly in pre-op between JUNCT and CONTROL. In post-op, PI-LL was significantly different between JUNCT and CONTROL (p=0.04, unpaired t-test). The regression model of PT vs PI was significantly different between JUNCT and CONTROL in pre-op (p=0.01, Z-test).

These results showed that failure is most common in long fused segments, likely due to long lever arms leading to implant failure. If the sagittal balance is not properly restored, after the surgery the balance is expected to worsen, eventually leading to failure: this effect was confirmed by the worsening of all the spinopelvic parameters before the revision surgery in JUNCT. Conversely, a good sagittal balance seems to avoid a revision surgery, as it is visible is CONTROL. The mismatch PI-LL after the fixation seems to confirm a good sagittal balance and predict a good correction. The linear regression of PT vs PI suggests that the spine deformity and pelvic conformation could be a predictor for the failure after a fixation.

Chordoma of the cervical spine is a rare but life-threatening disease with a relentless tendency towards local recurrence. Wide en bloc resection is recommended, but it is frequently not feasible in the cervical spine. Radiation therapy including high-energy particle therapy is commonly used as adjuvant therapy. The goal of this study was to examine treatment and outcome of patients with chordoma of the cervical spine.

Patients affected by cervical spine chordoma who underwent surgery at the Rizzoli Institute and University Hospital of Modena, between 2007 and 2021 were identified. The clinical, pathologic, and radiographic data were reviewed in all cases. Patient outcomes including local recurrence and disease-specific survival (DSS) were analyzed using chi-square test and Kaplan-Meier survival analysis.

Characteristics of the 29 patients (10 females; 19 males) included: median age at surgery 52.0 years (IQR 35.5 - 62.5 years), 10 (35%) involved upper cervical spine, 16 (55%) with tumors in the mid cervical spine, and 4 in the lower cervical spine (10%). Median tumor volume was 16 cm³ (IQR 8.7 - 20.8). Thirteen patients (45%) were previously treated surgically while 9 patients (31%) had previous radiation therapy. All patients underwent surgery: en bloc resection was passible in 4 patients (14 %), seventeen patients (59%) were treated with gross total resection while 8 patients (27%) underwent subtotal resection. Tumor volume was associated with a significantly higher risk of intraoperative complications (p < 0.01). Nineteen patients (65%) received adjuvant high-energy particle therapy. The median follow-up was 26 months (IQR 11 - 44). Twelve patients (41%) had local recurrence of disease. Patients treated with adjuvant high-energy particle therapy had a significant higher local control than patients who received photons or no adjuvant treatment (p = 0.01). Recurrence was the only factor significantly associated with worse DSS (p = 0.03 – OR 1.7), being the survival of the group of patients with recurrent disease 58.3% while the survival of the group of patients with no recurrent disease was 100%.

Post-operative high-energy particle therapy improved local control in patients with cervical chordoma after surgical resection. Increased tumor volume was associated with increased risk of intraoperative complications. Recurrence of the disease was the only factor significantly associated with disease mortality.

Abstract

Objectives. Intramedullary fixation is considered the most stable treatment for pertrochanteric fractures of the proximal femur and cut-out is one of the most frequent mechanical complications. In order to determine the role of clinical variables and radiological parameters in predicting the risk of this complication, we analysed the data pertaining to a group of patients recruited over the course of six years. Methods. A total of 571 patients were included in this study, which analysed the incidence of cut-out in relation to several clinical variables: age; gender; the AO Foundation and Orthopaedic Trauma Association classification system (AO/OTA); type of nail; cervical-diaphyseal angle; surgical wait times; anti-osteoporotic medication; complete post-operative weight bearing; and radiological parameters (namely the lag-screw position with respect to the femoral head, the Cleveland system, the tip-apex distance (TAD), and the calcar-referenced tip-apex distance (CalTAD)). Results. The incidence of cut-out across the sample was 5.6%, with a higher incidence in female patients. A significantly higher risk of this complication was correlated with lag-screw tip positioning in the upper part of the femoral head in the anteroposterior radiological view, posterior in the latero-lateral radiological view, and in the Cleveland peripheral zones. The tip-apex distance and the calcar-referenced tip-apex distance were found to be highly significant predictors of the risk of cut-out at cut-offs of 30.7 mm and 37.3 mm, respectively, but the former appeared more reliable than the latter in predicting the occurrence of this complication. Conclusion. The tip-apex distance remains the most accurate predictor of cut-out, which is significantly greater above a cut-off of 30.7 mm. Cite this article: G. Caruso, M. Bonomo, G. Valpiani, G. Salvatori, A. Gildone, V. Lorusso, L. Massari. A six-year retrospective analysis of cut-out risk predictors in cephalomedullary nailing for pertrochanteric fractures: Can the tip-apex distance (TAD) still be considered the best parameter?. Bone Joint Res 2017;6:481–488. DOI: 10.1302/2046-3758.68.BJR-2016-0299.R1

Purpose: Surgery is the mainstay treatment for chondro-sarcoma. About 35–40% of these tumours are located in the pelvis. Treatment requires significant sacrifices to ensure acceptable survival. Material and methods: This retrospective analysis of ten patients treated between 1993 and 2001 for pelvic chon-drosaromas was undertaken to examine survival and functional sequelae as a function of treatment and tumour grade. All patients had primary chondrosarcoma. The population included seven men and three women, mean age 50.9 years (range 28–77). Mean survival was 39.7 months. A biopsy was obtained in all cases (seven under scan guidance). Six patients required complementary surgical biopsy. According to the O’Neel and Ackermann classification, the tumours were grade I in five patients, grade II in two, grade III in three. Tumour classification according to the Enneking topography was: zone I one patient, zone I and II one patient, zone I+II+III one patient, zone II three patients, zone II+III three patients, and zone III one patient. Careful search for extension failed to identify metastasis preoperatively in any patient. For six patients, tumour resection was performed without reconstruction. Resection was associated with a Pugent reconstruction in three patients. All patients were reviewed with an AP view of the pelvis and a chest x-ray. Results: In sano resection was achieved in eight out of nine patients. For the ninth patient, resection was marginal according to the pathology report. Postoperative survival revealed the presence of metastasis in three patients. One patient developed recurrent tumour. At last follow-up, two patients had died and one had multiple metastases. Seven are currently disease free. Early postoperative complications occurred in 80% of the patients. Discussion: Currently, surgery remains the treatment of choice for pelvic chondrosarcoma, despite the major perioperative morbidity. Reconstruction, if attempted must always respect the rules of carcinological resection. Reconstruction does not appear to be mandatory since the rate of secondary and late complications remains particularly high in the case of extensive reconstruction. Histological grade, tumour size and quality of surgical resection are the predominant prognostic factors

Periprosthetic joint infections (PJIs) centers are garnering the attention of different arthroplasty surgeons and practices alike. Nonetheless, their value has yet to be proven. Therefore, we evaluated weather PJI centers produce comparable outcomes to the national average of THA PJIs on a national cohort.

We performed a retrospective review of patient data available on PearlDiver from 2015 – 2021. PJI THA cases were identified through ICD-10 and CPT codes. Patients treated by 6 fellowship trained arthroplasty surgeons from a PJI center were matched based on age, gender, Charlson Comorbidity Index and Elixhauser comorbidity index at a 1:1 ratio to patients from the national cohort. Compared outcomes included LOS, ED visits, number of patients readmitted, total readmissions. Sample sized did not allow the evaluation of amputation, fusion or explantation. Normality was tested through the Kolmogorov-Smirnov test. And comparisons were made with Students t-tests and Chi Square testing.

A total of 33,001 THA PJIs and were identified. A total of 77 patients were identified as treated by the PJI center cohort and successfully matched. No differences were noted in regard to age, gender distribution, CCI or ECI (p=1, 1, 1 and 0.9958 respectively). Significant differences were noted in mean LOS (p<0.43), number of patients requiring readmissions (p=0.001) and total number of readmission events (p<0.001). No difference was noted on ED visits.

Our study demonstrates that a PJI for THA cases may be beneficial for the national growing trend of arthroplasty volume. Future data, that allows comparison of patient's specific data will allow for further validation of PJI centers and how these can play a role in helping the national PJI growing problem.

Until today it is unknown whether preservation of the joint capsule positively affects patient reported outcome (PROs) in DAA-THA. A recent RCT found no clinical difference at 1 year. Since 2015 we preserve the capsule suture it at the end. We here evaluate whether this change had any effect on PROs and revisions, 2 years post-operatively.

Two subsequent cohorts operated by the senior author were compared. The capsule was resected in the first cohort (January 2012 – December 2014) and preserved in the second cohort (July 2015 – December 2017). No other technical changes have been introduced between the two cohorts. Patient demographics, Charlson Comorbidity Index (CCI), and surgical data were collected from our clinical information system. 2-years PROs questionnaires (OHS, COMI Hip) were obtained. Data was analyzed with generalized multiple regression analysis.

430 and 450 patients were included in the resected and preserved cohorts, respectively. Demographics, CCI surgical time and length of stay were equal in both groups. Blood loss was less in the preserved cohort (p<.05). Four patients had a revision (1 vs 3, n.s.). Once corrected for demographics, capsule preservation had significant worse PROs: +0.24 COMI (p<.001) and −1.6 OHS points (p<.05), however, effects were much smaller than the minimal clinically important difference (0.95 and 5 respectively). The date of surgery (i.e. surgeon's age) was not a significant factor.

In this large retrospective study, we observed statistically significant, but probably clinically not relevant, worse PROs with capsule preservation. It might be speculated that the not resected hypertrophied capsule could have caused this difference.

There has been significant interest in day-case and rapid discharge pathways for unicompartmental knee replacements (UKR). Pathways to date have shown this to be a safe and feasible option; however, no studies to date have published results of rapid-discharge pathways using the NAVIO robotic system. To date there is no published experience with rapid discharge UKR patients using the NAVIO robotic system. We report an initial experience of 11 patients who have safely been discharged within 24 hours. With the primary goal of investigating factors that led to rapid discharge and a secondary goal of evaluating the safety of doing so.

All patients were discharged within 24 hours; there were no post-operative complications and no readmissions to hospital. The mean length of stay was 16.9 hours (SD=7.3), with most patients seen once on average by physiotherapy. Active range of motion at 6 weeks was 0.7o to 130.5 o, with all patients mobilising independently. The average 6-month post-operative Oxford Knee Score was 43.5 out of 48. There were no readmission or complications in any of our patients.

This initial feasibility study identified that patients could be safely discharged within 24 hours after UKR using the NAVIO robotic system. With growing uptake of robotic procedures, with longer operative durations than traditional procedures, it is essential to ensure a rapid discharge to reduce healthcare cost whilst ensuring that patients are discharged home in a safe manner.

Purpose: This retrospective analysis was designed to determine the contribution of arthroscopy in the management of moderately stiff elbows arising from degenerative disease or trauma. Material and methods: Between 1992 and 2001, we performed 31 arthroscopic examinations of the elbow in patients with moderately stiff elbows. Mean preoperative motion was 94.8°. Men age at surgery was 41.6 years; there were nine women and 22 men. The dominant side was involved in 70% of the cases. Twentyfive patients were available for clinical review at a mean 32 months follow-up (range 5 months to 9 years). The causal event was trauma in 13 cases. The stiff elbow was a consequence of degenerative disease in 13 cases with no notion of trauma. Three elbows had been exposed to repeated microtrauma. For the majority of the cases, the intervention consisted in an anterior time via two portals then a posterior time. In five cases, anterior capsulotomy was performed. The other interventions were limited to joint cleaning. For two elbows, we used the Kashiwagi Outerbridge technique. Neurolysis of the ulnar nerve was performed at the elbow level during the same operative time. Results: Elbow motion in flexion was significantly improved after arthroscopy (P=0.01) and the flexion of the stiff elbow was reduced significantly (P=0.0001). At last follow-up none of the patients felt arthroscopy had worsened the elbow condition. The gain in joint motion was 25°. This gain was significantly greater when we performed anterior capsulotomy at the end of the procedure (P< 0.001). In three cases, there was a postoperative loss of motion. We did not have any intra or postoperative complications. Eighty percent of the patients felt arthroscopy had improved their elbow. Discussion: Arthroscopy of the stiff elbow arising from variable causes remains a difficult intervention which in our series provided gain in motion comparable to that reported in other series in the literature. This could be an interesting less invasive alternative to open surgery in the case of moderately stiff elbow

Introduction and Objective

The coronavirus (Covid-19) pandemic, first identified in China in December 2019, halted daily living with mandatory lockdowns imposed in Israel in March 2020. This halt induced a sedentary lifestyle for most citizens as well as a decreased physical activity time. These are both common risk factors for the development of low back pain (LBP) which is considered a major global medical and economical challenge effecting almost 1 in 3 people and a leading cause of Emergency Department (ED) visits. It is hypothesized that prevalence of minor LBP episodes during the first total lockdown should have increased compared to previous times. However, due to “Covid-19 fear” we expect a decrease in ED visits. We also speculate that rate of visits due to serious spinal illness (causing either immediate hospitalization or spinal surgery within 30-days of presentation) did not change.

Introduction

Distal femur fracture fixation in elderly presents significant challenges due to osteoporosis and associated comorbidities. There has been an evolution in the management of these fractures with a description of various surgical techniques and fixation methods; however, currently, there is no consensus on the standard of care. Non-union rates of up to 19% and mortality rates of up to 26 % at one year have been reported in the literature. Delay in surgery and delay in mobilisation post-operatively have been identified as two main factors for high rate of mortality. As biomechanical studies have proved better stability with dual plating or nail-plate combination, a trend has been shifting for past few years towards rigid fixation to allow early mobilisation. Our study aims to compare outcomes of distal femur fractures managed with either single plate (SP), dual plating (DP) or nail-plate construct (NP).

Introduction

Acute ankle injuries are commonly seen in musculoskeletal practice. Surgical management is the gold standard for lateral ligament injury in those with failed conservative treatment for a minimum of six months. Several studies have shown good functional outcome and early rehabilitation after MBG repair with an internal brace augmentation which is a braided ultrahigh molecular weight polyethylene ligament used to enhance the repair that acts as a secondary stabiliser. Hence the aim of the study was to compare the results with and without augmentation.

Introduction. In recent years, there has been an increase in hip joint replacement surgery using short bone-preserving femoral stem. However, there are very limited data on postoperative periprosthetic fractures after cementless fixation of these stem although the periprosthetic fracture is becoming a major concern following hip replacement surgery. The purpose of this study is to determine incidence of postoperative periprosthetic femoral fractures following hip arthroplasty using bone preserving short stem in a large multi-center series. Materials & Methods. We retrospectively reviewed 897 patients (1089 hips) who underwent primary total hip arthroplasty (THA) or bipolar hemiarthroplasty (BHA) during the same interval (2011–2016) in which any other cementless, short bone-preserving femoral stem was used at 7 institutions. During the study, 1008 THAs were performed and 81 BHAs were performed using 4 different short femoral prostheses. Average age was 57.4 years (range, 18 – 97 years) with male ratio of 49.7% (541/1089). Postoperative mean follow-up period was 1.9 years (range, 0.2 – 7.9 years). Results. Overall incidence of postoperative periprosthetic femoral fractures was 1.1% (12/1089). The mean age of these 12 patients were 71.2 year (range, 43 – 86 years). Seven patients were female and other 5 were male. Time interval between primary arthroplasty and fracture were mean 1.1 years (range, 0.1 – 4.8 years). Injury mechanism is a slip in 10 fractures and fall from 1m or less in 2. Three fractures occurred after BHA while 9 occurred after THA. Four fractures were in type AG and other 8 were in type B1 according to Vancouver classification. Of the 4 with AG type, 2 underwent open reduction and internal fixation and 2 took conservative management. Of the 8 with B1 type, 6 underwent open reduction and internal fixation and 2 took conservative management. Conclusion. The prevalence of postoperative periprosthetic femoral fractures was 1.1% in a multicenter retrospective analysis of 1089 hips. Our findings suggest that postoperative periprosthetic fracture can occur after hip replacement surgery using short bone-preserving stem although the incidence is relatively low

Background

In the United Kingdom (UK), the fastest growing population demographic is the over 85 years of age, but despite this, outcomes achieved in the octogenarian population with a Unicompartmental Knee Replacement (UKR) are underrepresented in the literature. The Elective Orthopaedic Centre, Epsom, has an established patient reported outcome measures (PROMs) programme into which all patients are routinely enrolled. We aim to investigate the outcome of medial UKR using the oxford phase 3 implant in octogenarians.

Purpose: This retrospective analysis was based on observations in 15 patients, seven men and eight women, mean age 48 years (19–72) treated between 1988 and 2000 at the Curie Institute. The tumour was located in limbs in eight patients (one humerus, two femurs, four tibias, one fibula), in the axial skeleton in five (four pelvi, one sacrum), and in the rib cage and the scapula in one each. Histology examination of the dedifferentiated component displayed fibrosacroma in six cases, HFM in two, rhabdomyosarcoma in two and leiomyosarcoma and osteosarcoma in one each. Six patients were given neoadjuvant and adjuvant chemotherapy of the osteosarcoma type and underwent conservative surgery of the affected limb in three out of four cases. Total histological necrosis was observed in three out of six cases. Six patients were given adjuvant treatment alone using an osteosarcoma protocol. Three unoperable patients were given palliative chemotherapy and radiotherapy. Results: Nine patients died from their disease. The most frequent metastatic site was the lung; mean survival was 20 months. Six patients survived including five with no progression (1+, 5+, 6+, 7+, 12+ years). Three out of five had had preoperative chemotherapy with a complete histological response and two out of five had had osteosarcoma protocol adjuvant chemotherapy. Conclusion: Dedifferentiated chondrosarcoma is generally considered to have very poor prognosis and should lead to an adapted therapeutic strategy. In our series, the osteosarcoma protocol provided complete histological response in three out of six patients. Five patients had prolonged survival, all had been given an osteosarcoma type chemotherapy protocol

Purpose: A retrospective analysis was conducted of 82 orthopedic injury cases sustained by IDF military personnel during the recent low intensity conflict (the second Palestinian uprising) which is characterized by many casualties and high availability of medical services and evacuation means. Methods: Records of all orthopaedic combat casualties evacuated to two level–I trauma centers between November 2002 and October 2005 were reviewed. Data included demographics, evacuation time, location of wounds, wounding agents, associated injuries, early/ late care and complications. Results: There were 51 patients (62%) injured by fire-arms and 31 patients (38%) by fragments and explosives. Mean evacuation time was 60 (± 22) minutes. The spectrum of injuries included soft tissue injury −43 (52%), open fracture−40 (48%), neurologic injury-19 (23%), vascular injury-7 (8%) and amputation −1 (1%). The most common procedure was debridement and irrigation (D& I) which was performed on 70 patients (85%). 19% of the open fracture patients underwent primary internal fixation. The mean length of hospitalization was 5 days (range 1–36). A multivariate statistical analysis was done, and it was found that being included in more than one category stands alone as the only predictor for prolonged hospitalization. Infection rate was 9.7%, with length of stay being the only parameter associated with infection. Conclusion: The recent low intensity conflict is an excellent example of early and aggressive trauma care, with an increased use of primary internal fixation. There is a high incidence of open fractures (48% of all extremity injuries) and a low amputation rate (1%). Multiple operative procedures have been shown to be successful at limb salvage, but are time intensive

Open talus fracture are notoriously difficult to manage and they are commonly associated with a high level of complications including non-union, avascular necrosis and infection. Currently, the management of such injuries is based upon BOAST 4 guidelines although there is no suggested definitive management, thus definitive management is based upon surgeon preference. The key principles of open talus fracture management which do not vary between surgeons, however, there is much debate over whether the talus should be preserved or removed after open talus fracture/dislocation and proceeded to tibiocalcaneal fusion.

A review of electronic hospital records for open talus fractures from 2014-2021 returned foureen patients with fifteen open talus fractures. Seven cases were initially managed with ORIF, five cases were definitively managed with FUSION, while the others were managed with alternative methods. We collected patient's age, gender, surgical complications, surgical risk factors and post-treatment functional ability and pain and compliance with BOAST guidelines. The average follow-up of the cohort was four years and one month. EQ-5D-5L and FAAM-ADL/Sports score was used as a patient reported outcome measure. Data was analysed using the software PRISM.

Comparison between FUSION and ORIF groups showed no statistically significant difference in EQ-5D-5L score (P = 0.13), FAAM-ADL (P = 0.20), FAAM-Sport (P = 0.34), infection rate (P = 0.55), surgical times (P = 0.91) and time to weight bearing (P = 0.39), despite a higher proportion of polytrauma and Hawkins III and IV fractures in the FUSION group.

FUSION is typically used as second line to ORIF or failed ORIF. However, there are a lack of studies that directly compared outcome in open talus fracture patients definitively managed with FUSION or ORIF. Our results demonstrate for the first time, that FUSION may not be inferior to ORIF in terms of patient functional outcome, infection rate, and quality-of-life, in the management of patients with open talus fracture patients. Of note, as open talus fractures have increased risks of complications such as osteonecrosis and non-union, FUSION should be considered as a viable option to mitigate these potential complications in these patients.

Aims

The aim of this study was to assess the incidence the microbiological spectrum and clinical outcome of hip and knee revision arthroplasties with unexpected-positive-intraoperative-cultures (UPIC) at a single center with minimum follow up of 2 years.

Purpose of the study: Fracture dislocations are complex injuries compromising elbow stability and functional potential. The treatment of these injuries should restore the exact anatomy of the joint, the only guarantee for a good functional outcome. The purpose of our work was to analyse our results and review the literature in order to establish an evidence-based therapeutic algorithm essentially based on the type of associated fracture. Material and methods: This was a retrospective analysis of 15 cases (12 men, 3 women) reviewed at mean 18 months. The causal event was a fall in most patients, followed by traffic and sports accidents. This was a first-intention treatment for 12 patients and a second-intention intervention for three. Initially, none of the patients presented vessel or nerve injury. There were three open fractures. The most common fracture was: radial head (n=12), coronoid process (n=9). One or two approaches were used, depending on the type of associated fracture. Treatment consisted in fixation of the radial head (n=8) and arthroplasty (n=4).. The coronoid process was fixed in six cases. All ligament tears were repaired. An articulated external fixator was used in four cases. Results: All patients had a stable elbow. Mean flexion was 125, extension -16, pronation 72 and supination 63. Wrist force was 80% compared with the controlateral side. The Mayo Clinic function score was 84 points. Discussion: Reconstruction of the lateral osteoligament column, associated with fixation of the coronoid, restores stability in the majority of elbows. For very high energy injuries with complex bone and ligament damage, addition of an articulated external fixator is indispensable to enable early mobilization. Stiffness and instability are the most common complications after traumatic injury. Conclusion: Fracture dislocations of the elbow are complex injuries requiring adequate emergency care, with surgery as needed, for all lesions at the same time via one or two approaches followed by early rehabilitation. The function outcome depends on the intraoperative stability achieved and early mobilization

Introduction

Fracture and deformity after frame removal is a known risk in 9–14.5% of patients after circular frame treatment. The aims of this study were to assess the effectiveness of our staged protocol for frame removal and risk factors for the protocol failure.

Rib fractures (RF) represent the most common bone fracture after blunt trauma, occurring in 10–20% of all trauma patients and leading to concomitant injuries of the inner organs in severe cases. However, a standardized classification system for serial rib fractures (SRF) does still not exist. Basic knowledge about the facture pattern of SRF would help to predict organ damage, support forensic medical examinations, and provide data for in vitro and in silico studies regarding the thoracic stability. The purpose of our study was therefore to identify specific SRF patterns after blunt chest trauma.

All SRF cases (≥3 subsequent RF) between mid-2008 and end of 2015 were extracted from the CT database of our University Hospital (n=383). Fractures were assigned to anterior, antero-lateral, lateral, postero-lateral, and posterior location within the transverse plane (36° each) using an angular measuring technique (reliability ±2°). Rib level, fracture type (transverse, oblique, multifragment, infracted), as well as degree of dislocation (none, </≥ rib width) were recorded and each related to the cause of accident.

In total, 3747 RF were identified (9.7 per patient, ranging from 3 (n=25) to 33 (n=1)). On average, most RF occurred in crush/burying injuries (15.9, n=13) and pedestrian accidents (12.2, n=14), least in car/truck accidents (8.8, n=76). Altogether, RF gradually increased from rib 1 (n=140) towards rib 5 (n=517) and then decreased towards rib 12 (n=49), showing a bell-shaped distribution. More RF were detected on the left thorax (n=2027) than on the right (n=1720). Overall, most RF were found in the lateral (33%) and postero-lateral (29%) segment. Posterior RF mostly occurred in the lower thorax (63%), whereas anterior (100%), antero-lateral (87%), and lateral (63%) RF mostly appeared in the upper thorax. RF were distributed symmetrically to the sagittal plane, showing a hotspot (up to 98 RF) at rib levels 4 to 7 in the lateral segment and rib level 5 in the antero-lateral segment. In the car/truck accident group, 47% of all RF were in the lateral segment, in case of frontal collision (n=24) even 60%. Fall injuries (n=141) entailed mostly postero-lateral RF (35%). In case of falls >3 m (n=45), 48% more RF were detected on the left thorax compared to the right. CPR related SRF (n=33) showed a distinct fracture pattern, since 70% of all RF were located antero-laterally. Infractions were the most observed fracture type (44%), followed by oblique (25%) and transverse (18%) fractures, while 46% of all RF were dislocated (15% ≥ rib width).

SRF show distinct fracture patterns depending on the cause of accident. Additional data should be collected to confirm our results and to establish a SRF classification system.

Objective: Diagnostic delay is well recognised in soft tissue sarcoma (STS). The aim of this paper is to assess whether symptom duration/time to diagnosis, has any impact on patient survival and also if patient and tumour-related factors are related to the duration of symptoms prior to presentation. Method: We performed a retrospective analysis of prospectively collected data for all patients diagnosed or treated with STS at our centre over a 20-year period. Information regard¬ing when the patients first experienced symptoms was entered into a local oncology database at their first consultant-outpatient appointment. Symptom duration was defined as time in weeks from first symptoms experienced by the patient to the time of diagnosis. Data analysis was performed using StatView and R. Risk factors were assessed by Kaplan-Meier analysis and the Cox proportional hazards model. Stat¬istical significance was determined using 95% confidence intervals where appropriate. Students t-test was used to compare categorical data. Results: The study population comprised 1508 patients. 159 had metastatic disease at diagnosis and overall 5-year survival in this group was 14%. In view of this poor prognosis these patients were excluded from further analyses. In the remaining 1349 patients overall 5-year survival was 60%. Mean symptom duration within our study was 70.2 weeks. A Cox Proportional hazards model showed that duration of symptoms had a significant impact on survival (p=0.0037) with each additional week of symptoms reducing the monthly hazard rate by 0.2%. Patient and tumour-related factors that were significantly associated with longer symptom durations were low grade, subcutaneous tumours, and those patients with either epitheliod or synovial sarcomas. Symptom duration was not associated with tumour size or patient age/gender. Conclusion: Patients presenting with long symptom durations/diagnostic delay, tend to have low grade disease and a more favourable outcome than patients who experience short symp¬tom durations

Aims: The purpose of this study is to determine the causes of failed medial Oxford unicompartmental knee arthroplasty (UKA) and assess the outcome after revision surgery.

Materials And Methods: From 1993 to 2003, sixty-nine Oxford UKA (58 patients) were revised to a total knee replacements (TKR) at this centre. The type of implant used at revision surgery, pre- and post-revision American Knee Society (AKS) and Tegner scores were analyzed retrospectively.

Results: The patient’s mean age at the time of UKA was 64.5 years (range: 50–79). The average pre-revision scores were as follows: AKS-Objective score was 41.2 (± 10.4), the AKS-functional score was 56.8 (±10.0) and the average Tegner score was 1.5 (±0.6). The mean follow-up period was 38.3 (range: 12–107) months. The common causes of failure were: lateral compartment osteoarthritis (34.0%), component loosening (30.4%) and early or late infection requiring two-stage revision surgery (14.3%). The majority were revised using a standard primary TKR implant and only six (9%) requiring augmentation stems. Patellar resurfacing was performed in 25% of cases. The mean polyethylene liner width of the revision TKR was 13.4mm (±3.7). The average post-revision scores were: AKS-Objective score 77.4 (±13.1), the AKS-functional AKS score 70 (±21.1) and the average Tegner score of 2.2 (±0.8). Three knees needed rerevision for infection of the revised implant.

Conclusions: Lateral compartment osteoarthritis was the commonest indication for revision surgery for a failed medial Oxford UKA. Revision of a UKA is technically easier and the results are superior to the published results of revision of a primary TKR. In more than 90% cases, no augmentation or stemmed implants were necessary.

Objective To analyse RTA admissions to BMH Shaibah with respect to seatbelt usage, position in vehicle, age, type of injury and mechanism of injury. Design Retrospective analysis of discharge summaries and hospital notes. Subjects All service personnel admitted to BMH Shaibah due to RTA. Results During the study there were 315 reported RTAs, 3 fatalities and 47 inpatient admissions. 87% of admissions were male; in 32% of cases the vehicle had rolled and 28% of individuals admitted had been ejected from the vehicle. 85% of individuals had not been wearing seatbelts, and none of the ejected individuals had been restrained. 92% of those ejected were travelling in the rear of the Landrover. Of those ejected, 38% suffered more than one type of injury and 62% suffered a fracture, (accounting for 50% of all fractures admitted). 34% of admissions had sustained a fracture and would be evacuated to the UK. Conclusions These figures correlate well with previous evidence showing the likelihood of serious injury is increased by more than 300% if the patient is ejected. Those travelling in the rear of a Landrover would appear to be in the most dangerous position. Seatbelts are the single most effective means of reducing fatal and non-fatal injuries in motor vehicle accidents. Standing Orders states that seatbelt use is mandatory, but compliance is poor. This may be due to misconceptions on the relative dangers faced by soldiers in Iraq. Education and enforcement needs to be more effective if the Army is to reduce the number, and seriousness, of injuries attributable to RTAs

Purpose of the study: Orthopedic treatment is generally proposed for minimally displaced fractures of the scapula. Surgery is indicated in the event of medialization or disorientation of the glenoid cavity. The purpose of this study was to identify rules for management of problematic cases.

Material and methods: This retrospective study included 27 patients, 22 men and five women, mean age 46.7 years (range 22–83 years). The fracture was limited to the scapula in 17 and was part of thoracic syndrome in ten. Injury to the plexus was noted in three patients. Associated lesions were noted in 55% of patients. Orthopedic treatment was proposed for 15 patients (group 1) and surgical treatment for 12 (group 2): neck osteosynthesis (n=4), clavicle fixation (n=5), combined osteosynthesis (n=3).

Results: Mean follow-up was 47.3 months; 21 patients were reviewed (four lost to follow-up, two deaths). Per primam healing was achieved for all fractures. There were no complications related to the surgical procedure in group 2 and no secondary displacement in either group. Mean time to resumed occupational activity was four months (range 0.2–25 months): 2.2 months (1–5 months) in group 1 and 5.5 months (0.2–25 months) in group 2. The age and gender weighted Constant score for the overall series was 96.2% (range 80–100%) with 81% excellent and very good functional outcomes. In group 1, the Constant score was 95.4% (81–100%) with 70% excellent and very good functional outcomes. It was 97% (80–100%) in group 2 with 91% excellent results. At last follow-up, there was only one case of Samilson grade 2 osteoarthritis.

Discussion and conclusion: The functional outcome observed after treatment of scapular fractures is satisfactory. Orthopedic treatment should be reserved for non-displaced fractures. If there is significant medial offset of the glenoid cavity or instability, osteosynthesis of the scapular neck is indicated, possibly with reinforcement by fixation of the clavicle. Isolated osteosynthesis of the clavicle stabilizes the scapular ring but does not reduce the scapular fracture.

Objectives. This paper describes the outcomes obtained from a 12 hour group based multidisciplinary functional restoration programme for patients with persistent low back pain who presented with psychosocial obstacles to recovery. The programme was designed to address modifiable psychosocial obstacles to recovery over a four week period, reduce pain related disability, improve pain self-efficacy and reduce patients' reliance on analgesic medication. Design. A single group retrospective analysis. Participants. Data from 54 participants with non-specific low back pain (Male = 26. Female =28, mean age 43.7yrs) who attended a four week functional restoration programme between September 2012 and June 2013 were analysed. Results. There was a statistically significant improvement between Oswestry Disability Index and Pain Self Efficacy scores before and after the treatment intervention, and at 9 month follow-up (p<0.001). When only scores at the end of the treatment intervention and month 9 were compared there was no significant difference (p=0.184 for ODI, p=0.341 for PSEQ). Patients also self-reported reduced reliance on analgesic medication after the treatment intervention and at 9 month follow-up. Conclusion. The findings indicate that a group based multidisciplinary functional restoration programme for patients with persistent low back pain, which targets modifiable obstacles to recovery, can be effective in reducing disability, improving self-efficacy and reducing reliance on medication in both the short and medium term. This article has also been published online in Wiley Online Library (. wileyonlinelibrary.com. ) DOI: 10.1002/msc.1078 in Musculoskeletal Care Journal (2014) © 2014 John Wiley & Sons, Ltd. Conflicts of interest: No conflicts of interest. Sources of funding: No funding obtained

Aim

Bumps and lumps of the hand are a common cause for consultation in general practice. However not all of these lesions are of true neoplastic nature and malignant tumours are a rarity in this location.

Due to limitations of existing pharmacological therapies for the management of chronic pain in osteoarthritis (OA), surgical interventions remain a major component of current standard of care, with total joint replacements (TJRs) considered for people who have not responded adequately to conservative treatment. This study aimed to quantify the economic burden of moderate-to-severe chronic pain in patients with OA in England prior to TJR.

A retrospective, longitudinal cohort design was employed using Clinical Practice Research Datalink GOLD primary care data linked to Hospital Episode Statistics secondary care data in England. Patients (age ≥18 years) with an existing OA diagnosis of any anatomical site (Read/ICD-10) were indexed (Dec-2009 to Nov-2017) on a moderate-to-severe pain event (which included TJR) occurring within an episode of chronic pain. 5-year TJR rates from indexing were assessed via Kaplan-Meier estimates. All-cause healthcare resource utilisation and direct medical costs were evaluated in the 1–12 and 13–24 months prior to the first TJR experienced after index. Statistical significance was assessed via paired t-tests.

The study cohort comprised 5,931 eligible patients (57.9% aged ≥65 years, 59.2% female). 2,176 (36.7%) underwent TJR (knee: 54.4%; hip: 42.8%; other: 2.8%). The 5-year TJR rate was 45.4% (knee: 24.3%; hip: 17.5%; other: 6.8%). Patients experienced more general practitioner consultations in 1–12 months pre-TJR compared with 13–24 months pre-TJR (means: 12.13 vs. 9.61; p<0.0001), more outpatient visits (6.68 vs. 3.77; p<0.0001), more hospitalisations (0.74 vs. 0.62; p=0.0032), and more emergency department visits (0.29 vs. 0.25, p=0.0190). Total time (days) spent as an inpatient was higher in 1–12 months pre-TJR (1.86 vs. 1.07; p<0.0001). Mean total per-patient cost pre-TJR increased from £1,771 (13–24 months) to £2,621 (1–12 months) (p<0.0001).

Resource-use and costs incurred were substantially greater in the 12 months immediately prior to TJR, compared with 13–24 months prior. Reasons for increased healthcare and economic burden in the pre-TJR period deserve further exploration as potential targets for efforts to improve patient experience and efficiency of care.

Aim

This study aims to describe our department experience with single stage revision (SSR) for chronic prosthetic-joint infection (PJI) after total hip arthroplasty (THA) between 2005 and 2014 and to analyze success rates and morbidity results of patients submitted to SSR for infected THA according to pathogen.

Purpose: We report a retrospective continuous series of 107 total hip arthroplasties using a hydroxyapatite-coaated cup followed for a mean 9.67 years. We studied implant stability and component wear.

Material and methods: One hundred total hip arthroplasties were performed between January 1991 and January 1992. The series included 67 women and 40 men operated by the same surgeon who used the same Alizé cup and Aura cementless stem. Mean age at surgery was 66.5 years (range 30–85). Mean follow-up at review was 9.6 years. We retained 63 hips for analysis excluding 17 deaths, 16 patients lost to follow-up, 10 patients who could not be followed correctly, and only one implant ablation (0.9%). The implant was a first intention prosthesis in 90.7% of the cases and a second operation to replace a loosened primary prosthesis.

The Postel Merle d’Aubigné score was used to assess clinical outcome and all patients responded to a self administered questionnaire. Radiographically, we searched for signs of instability (tilt, displacement) and implant wear using precise digitalized measurements on successive digitalized x-rays with MetrOs software. We searched for qualitative radiological signs of bone reaction in contact with the implant.

Results: The overall PMA score improved from 10.63 preoperatively to 16.98 at the intermediary 5-year follow-up and was 15.77 at the 10-year follow-up. Satisfactory results were obtained in 93.9% of the patients at five years and 98.5% of the patients (64 hips) at 10 years. There were two fractures of the ceramic head after direct fall on the greater trochanter (requiring changing the femoral implant, the head and the polyethylene insert). There was one cup loosening at 9.5 years with verticalisation of the implant in an active athlete. Analysis of the x-rays did not demonstrate any abnormal condensation or lucent lines. Bony defects were observed in one case. The MetrOs radiographic data were available for 55 hips. At five years, mean wear was 0.53 mm, which increased to 0.76 mm at ten years (range 0.16 – 2.24 mm). Cup ascension was 0.15 mm at five years and 0.76 mm at 10 years. Mean cup tilt was 46.2° immediately after implantation and varied a mean 0.7° at five years and 1° at ten years.

Discussion and conclusion: This radioclinical study at ten years follow-up demonstrates that the hydroxyapa-tite surfaced Alizé implant is stable over time. The clinical results in this study were satisfactory with minimal regression of the PMA score related to patient ageing. The x-rays analysed with a rigorous and precise measurement instrument provided reassuring results. We discussed the one cup loosening and the clinical course of the two patients who underwent revision procedures after trauma-induced fracture of the ceramic head.

Purpose: We reviewed a series of pollicizations in children with congenital thumb malformations. The purpose of this study was to assess the influence of anatomic or technical factors on functional and cosmetic outcome.

Material: The series included 33 operations in 26 children. The Blauth classification was: grade IIIA (n=1), grade IIIB (n=8), grade IV (n=8), grade V (n=13), mirror hand (n=8). We noted the type of skin incision, technique used to fix the metacarpal head on the carpus, and tendon shortenings. Results were assessed at mean 4 years follow-up on the basis of the cosmetic aspect (parent satisfaction) and functional outcome measured with the Kapandji index and flexion-extension of inter-phalangeal joint, thumb finger opposition, and sensitivity.

Results: Mean age at surgery was 32 months. Fixation was achieved with sutures in 24 cases and pinning in nine. Tendon shortening was performed in 16 cases on the extensor system and in one case on the deep flexor system. Mean follow-up was four years. There was no significant difference between groups A and B for cosmetic outcome. The main factor influencing objective functional outcome was the association of a grade III or IV radial club hand. In these patients, the final outcome was compromised by the stiffness or deformation of the radiocarpal joint and the stiffness of the preoperative Kapandji index which was 7 (mean) in group A and 4.75 in group B.

Discussion and conclusion: The following technical aspects did not have a significant effect on the final functional result in our series: type of skin incision, type of carpal fixation, shortening the extensor or flexor system. Technical aspects which must be performed with particular care include reconstruction of the thenar muscles using interosseous muscles, curettage of the growth cartilage of the head of the second metacarpus, and hyper-extension of the head of the second metacarpus during fixation onto the carpus. Careful technique avoids future complications such as excessive growth of the neometa-carpus or Z-thumb.

Purpose: We reviewed retrospectively 40 ligamentoplasties of the anterior cruciate ligament in patients who had undergone several prior reconstructions (1 to 6). The initial operation had used a synthetic ligament in 13 cases, patellar tendon in 23 and divers implants in four.

Material and methods: Forty patients, 12 women and 28 men, with recurrent ligament tears where reoperated by the same surgeon. Mean age was 28.5 years (16–51). Mean follow-up after the last operation was 27 months. All patients were reviewed (history, physical examinatin and KT 1000); 20 of them responded to a self-administered questionnaire using the IKDC chart later after the clinical review, and 23 of the 40 had radiographs to measure laxity. Arthroscopic reconstruction was used in 33 cases. A surgical procedure was necessary on a peripheral ligament in six cases and osteotomy for tibial valgisation in one. Reconstruction was achieved with the quadriceps tendon in 11 cases, the patellar tendon in 18, the hamstrings in eight and Mac in Jones in three. The IKDC score was used for clinical assessment with manual arthrometric measurement of laxity. Radiographs were obtained to measure the anterior drawer of the medial and lateral compartments of both knees for right-left and pre-postoperative comparisons.

Results: The initial handicap was marked (IKDC: 18 D, 21 C, 1 B). Reconstruction was good or very good in 72.5% of the knees (IKCD: 2 A, 27 B, 10 C, 1 D). Self-evaluation revealed 25% painful knees for intense activities. Laxity was improved with a mean differential gain of 5.35 mm of the maximal pre- and postoperative KT 100 (7.24 versus 1.89). Among the 24 knees with radiographic assessment, the mean differential preoperative was 9.14 mm preoperatively and 4.69 mm at last follow-up giving a gain of 4.45 mm. One athlete was able to resume sports activities at the same or higher level and others at a lower level.

Discussion, conclusion: This study confirms that the results obtained after revision repair are less satisfactory than after primary repair. This homogeneous (one operator) and large series with a sufficient follow-up can be compared with the rare published series. Each ligament reconstruction is specific and warrants a specific surgical approach adapted to each individual case.

Background: Arthrodesis is still the recommended treatment for end-stage hallux rigidus in young and active patients. Silicone implant arthroplasty of great toe was first described back in 1979 by Swanson et. al. Over the years, total joint replacement arthroplasty has taken over, as the apparent complication rate with silicone appeared high.

Objective: The objective of this retrospective study was to analyse medium to long-term clinical outcomes and patient satisfaction of patients with silastic implant arthroplasty of great toe.

Methods: Between May 1996, and December 2004, 65 patients totalling 76 first metatarsophalangeal silastic implants were evaluated both subjectively and objectively. The group comprised of 25 males and 40 females with average age 56 years (26–86). The average time of follow-up was 6 years (2–11). 12 patients (18%) has previous metatarsal osteotomy with bunionectomy for hallux valgus.

Outcomes were assessed by overall subjective satisfaction, Visual Analogue Scale (VAS) for pain, functional scores, range of motion and radiographic evaluation.

Results: Overall success rate was over 80%. 90% patients reported good pain relief after the operation. All patients regained satisfactory range of movement in the joint. The average flexion was 110 (5–200) and extension 200 (10–300). None of the patients reported difficulty in walking or slow running.

6 patients (9%) complained of persisting mild to moderate pain and swelling in the joint. 2 patients (3%) were not happy with the level of deformity correction. All the above 8 patients declined to have joint arthrodesed. 2 patients (3%) had deep infection requiring implant removal. 1 patient had osteolysis on the x-rays but remain asymptomatic. Although radiographic deterioration of the implant was demonstrated in a lot of implants, this deterioration did not correlate with patient satisfaction.

We conclude that silastic first metatarsophalangeal joint replacement is a proven procedure that not only provides long- term pain relief but also satisfactory range of movement. Therefore it should still be considered as an option in patients with end-stage hallux rigidus.

Background

Fifteen to twenty percent of patients presenting for total hip arthroplasty (THA) have bilateral disease. While simultaneous bilateral THA is of interest to patients and surgeons, debate persists regarding its merits. The majority of previous reports on simultaneous bilateral THA involve patients in the lateral decubitus position, which require repositioning, prepping and draping, and exposure of a fresh wound to pressure and manipulation for the contralateral THA. The purpose of this study was to compare complications, component position, and financial parameters for simultaneous versus staged bilateral THAs using the direct anterior approach (DAA).

Objective

To evaluate functional and oncological outcomes following resection of sacral tumours and discuss the strategies for instrumentation.

Surgical Site Infection (SSI) is one of the most frequent nosocomial infections and depends on many factors: patient, microorganism, antiseptic solution use, antibiotic prophylaxis, hand scrubbing, wound care or hospital stay lenght.

With the present paper the authors aim to study the SSI incidence after Total Knee (TKA) or Hip Arthroplasty (THA).

All patients who underwent primary TKA or THA between January 2011 and May 2012 at our institution were considered. Patients who died within 1 year after the procedure of unrelated causes were excluded. Data collected included ASA classification, type of procedure, total and post-operative hospital stay, type and duration of antibiotic prophylaxis.

Data were collected from the consultation at 1 month and 1 year post-operative, clinical registries and telephone interview. SSI was defined according to the Centers for Disease Control and Prevention criteria. Suspected cases of SSI included antibiotic administration longer than 5 days or absence of antibiotic prescription, hospital stay after the procedure longer than 9 days, patient referring infection symptoms, and clinical data reports of infection or re-intervention.

During the studied period and after exclusion of 5 cases, a total of 251 surgeries (104 TKA, 147 THA) were performed, of which 2 were urgent.

For both TKA and THA, the average total hospital stay was 9 days (8 days post-operative). The majority were American Society of Anesthesiologists (ASA) classification 2 and 3.

There were 4 SSI (1,60%), 2 TKA (1,92%) and 2 THA (1,36%), all of them after discharge. Their average total hospital stay was 10,5 days.

Antibiotic prophylaxis was used in 93% of the patients (97,4% a cephalosporin), with an average length of 5,7 days.

Recommended hospital stay after a TKA or THA is about 5 days. On HELICS-CIRURGIA 2006–2010 report it was 10 days, similar to ours. In infected patients, our total hospital stay was lower (10,5 vs 26).

Recommended duration of antibiotic prophylaxis is 24h. On HELICS-CIRURGIA more than 50% had it for more than 24h, which also happened with us; our antibiotic coverage was similar.

Comparing to HELICS-CIRURGIA, the predominance of ASA 2 and 3 classifications was similar, but the overall SSI rate was lower (1,6% vs 2,24%).

We conclude we must reduce hospital stay and antibiotic duration and keep the surveillance of SSI after TKA or THA.

The records of 82 patients (129 feet) with resistant clubfoot deformity treated surgically by means of different releases were retrospectively reviewed. There are many treatment regimes for clubfoot. Some authors recommend manipulation with minimal multi-stage surgery, whereas others recommend neonatal corrective surgery. However, objective comparison of different treatment programs is not easy because different criteria are used to evaluate the results.

Teratologic or neuromuscular clubfeet were not included in this revision. Between 1982 and 1998, 82 patients (27 girls, 55 boys) with 129 clubfeet underwent surgical treatment. All feet were initially treated with a serial long-leg cast for a minimum of four months. Mean age at the time of first surgery was 5.5 months (range 3.5 to 24). Minimum follow-up was two years.

Primary posterior release was performed on 105 feet. Subsequent medial release was performed on 16 feet, posteromedial release on three, and a subtalar (Cincinnati) release on three. Primary isolated posteromedial release was performed on 14 feet, and two of these required a subsequent subtalar (Cincinnati) release. Primary isolated medial release was performed on seven feet.

Primary isolated lateral release was performed on one foot and primary isolated subtalar (Cincinnati) release was performed on two feet. Subsequent derotative tibial osteotomy was performed in seven cases, wedge tarsectomy on four feet, triple arthrodesis on five, and calcaneocuboid fusion on one foot.

Residual varus was present in seven feet. Calcaneal gait caused by overlengthening of the Achilles tendon occurred in one foot, and residual equinus in two feet. Residual valgus heel was observed in three feet.

The surgeon must assess each foot and plan the surgery accordingly. A total release is not required for every foot.

We retrospectively audited outcomes from 97 patients aged over 40 who had undergone arthroscopy in the last 4 years in this orthopaedic unit. The audit was carried out by way of questionnaires which were sent out to patients with the results inputted to a database combined with a review of patients charts, in particular the operative note from the arthroscopy. A standardised proforma was used to record both patient’s details and operative findings.

The questionnaires were sent out to 165 patients. Of that number 102 were returned, five of which were excluded due to inadequate information.

The average wait for surgery was 10 months and 6 patients noticed an improvement in symptoms while waiting for surgery. 80% of those waiting less than 1 year experienced an improvement compared to 73% of those waiting more than 1 year. The results showed that post-operative symptoms in 74 out of the 97 (77%) patients were improved, 12 (12%) remained unchanged with 11 (11%) experiencing a worsening in symptoms.

The age group 60+ had the best outcomes with 23 out of 26 (89%) experiencing some improvement in symptoms; males also experienced a better outcome with 51 out of 63 (81 %) achieving some improvement, compared to females where only 23 out of 34 (67%) showed improvement.

We did not have routine access to an MRI scanner so only 23 of the patients had a pre-operative scan. We have insufficient numbers to comment on the accuracy or otherwise of positive MRI findings.

Pre-operative symptoms of pain, swelling, locking and instability were recorded and their correlation to successful outcome analysed. This showed that the presence of these symptoms did not predict a post-operative improvement in symptoms as an equal number of those with any of these symptoms compared to those without derived benefit from the procedure. This finding is significant in that these symptoms are commonly used in clinical practice to predict the likely benefit from arthroscopy.

A pre-operative history of locking was a specific predictive symptom for meniscal injury in that 27 out of 33 (82%) patients with true locking as a symptom had a meniscal injury but only 27 out of 58 (47%) patients with a meniscal injury experienced locking as a symptom implying that it is not a sensitive indicator of meniscal damage.

We also enquired about the presence of a definite acute injury associated with the onset of symptoms. This also had no predictive value as to the potential benefit of surgery.

A significant negative from the study was the fact that a history of an acute injury gave no indication as to the presence of a meniscal injury and even if a meniscal injury was present the patient’s outcomes were not significantly better than if no injury was present.

In conclusion 77% of patients aged 40+ derived benefit from arthroscopy, possibly due to the effects of washing out the knee rather than any active intervention. A history of locking, pain swelling or an acute injury did not offer an accurate prediction of benefit from arthroscopy, therefore the elderly and those without a history of locking or acute injury should not be dissuaded from undergoing this procedure. This study is confined to those over 40 years of age and the findings are quite different to the findings in younger patients. These findings surprised the surgeons at our unit and therefore we feel may be an interesting and stimulating presentation at the B.A.S.K. meeting.

Aims. This study evaluated the definitions developed by the European Bone and Joint Infection Society (EBJIS) 2021, the International Consensus Meeting (ICM) 2018, and the Infectious Diseases Society of America (IDSA) 2013, for the diagnosis of periprosthetic joint infection (PJI). Methods. In this single-centre, retrospective analysis of prospectively collected data, patients with an indicated revision surgery after a total hip or knee arthroplasty were included between 2015 and 2020. A standardized diagnostic workup was performed, identifying the components of the EBJIS, ICM, and IDSA criteria in each patient. Results. Of 206 included patients, 101 (49%) were diagnosed with PJI with the EBJIS definition. IDSA and ICM diagnosed 99 (48%) and 86 (42%) as infected, respectively. A total of 84 cases (41%) had an infection based on all three criteria. In 15 cases (n = 15/206; 7%), PJI was present when applying only the IDSA and EBJIS criteria. No infection was detected by one definition alone. Inconclusive diagnoses occurred more frequently with the ICM criteria (n = 30/206; 15%) compared to EBJIS (likely infections: n = 16/206; 8%) (p = 0.029). A better preoperative performance of the EBJIS definition was seen compared with the ICM and IDSA definitions (p < 0.001). Conclusion. The novel EBJIS definition identified all PJIs diagnosed by any other criteria. Use of the EBJIS definition significantly reduced the number of uncertain diagnoses, allowing easier clinical decision-making. Cite this article: Bone Joint Res 2022;11(9):608–618

Background. Post operative analgesia is an important part of Total Knee Arthroplasty (TKA) to facilitate early mobilisation and patient satisfaction. We investigated the effect of periarticular infiltration of the joint with chirocaine local anaesthetic (LA) on the requirement of analgesic in the first 24 hrs period post op. Methods. Retrospective analysis of case notes was carried out on 28 patients, who underwent TKA by two different surgeons. They were divided into two groups of 14 each; who did and did not receive the LA infiltration respectively. All patients were given spinal morphine (162 mcg r: 150-200). Analgesic requirement was assessed in terms of the amount of paracetamol, morphine, diclofenac, oxynorm and tramadol administered in 24hrs post op including the operating time. Results. Following results were obtained from patients receiving LA infiltration vs no infiltration: Morphine; 70 mg vs 200 mg, Paracetamol; 60 gm vs 58 gms, Diclofenac; 1650 mg vs 1050 mg, Oxynorm; 40 mg vs 80 mg, Tramadol; 200 mg vs 400 mg. Average length of stay (LOS) was 6 days (r: 3-8) in both groups. Conclusion. From this study it may be concluded that periarticular LA infiltration reduces the requirement of morphine in first 24 hrs by almost 1/3rd. The amount of tramadol and oxynorm was also halved in LA infiltrated group although the requirement of paracetamol remained the same. LA infiltrated group received almost 1.5 times more Diclofenac as compared to the non infiltrated group. The LOS was not affected by the administration of LA

Aims. The burden of revision total hip arthroplasty (rTHA) continues to grow. The surgery is complex and associated with significant costs. Regional rTHA networks have been proposed to improve outcomes and to reduce re-revisions, and therefore costs. The aim of this study was to accurately quantify the cost and reimbursement for a rTHA service, and to assess the financial impact of case complexity at a tertiary referral centre within the NHS. Methods. A retrospective analysis of all revision hip procedures was performed at this centre over two consecutive financial years (2018 to 2020). Cases were classified according to the Revision Hip Complexity Classification (RHCC) and whether they were infected or non-infected. Patients with an American Society of Anesthesiologists (ASA) grade ≥ III or BMI ≥ 40 kg/m. 2. are considered “high risk” by the RHCC. Costs were calculated using the Patient Level Information and Costing System (PLICS), and remuneration based on Healthcare Resource Groups (HRG) data. The primary outcome was the financial difference between tariff and cost per patient episode. Results. In all, 199 revision episodes were identified in 168 patients: 25 (13%) least complex revisions (H1); 110 (55%) complex revisions (H2); and 64 (32%) most complex revisions (H3). Of the 199, 76 cases (38%) were due to infection, and 78 patients (39%) were “high risk”. Median length of stay increased significantly with case complexity from four days to six to eight days (p = 0.006) and for revisions performed for infection (9 days vs 5 days; p < 0.001). Cost per episode increased significantly between complexity groups (p < 0.001) and for infected revisions (p < 0.001). All groups demonstrated a mean deficit but this significantly increased with revision complexity (£97, £1,050, and £2,887 per case; p = 0.006) and for infected failure (£2,629 vs £635; p = 0.032). The total deficit to the NHS Trust over two years was £512,202. Conclusion. Current NHS reimbursement for rTHA is inadequate and should be more closely aligned to complexity. An increase in the most complex rTHAs at major revision centres will likely place a greater financial burden on these units. Cite this article: Bone Jt Open 2023;4(8):559–566

Aim

Our goals were to minimize the invasiveness of the revision hip arthroplasty approach in order to accelerate the patient's rehabilitation, shorten the length of hospitalization and reduce the postoperative complications, especially the rate of joint dislocation. Our study aimed to prove whether and under which conditions the less invasive approach is preferable in revision arthroplasty.

A series of 116 patients surgically treated, with exclusion of arthroplasty, between December 1996 and December 2002 for a fracture of the proximal humerus, was retrospectively reviewed. Only 44 patients (45 shoulders) were available for clinical and radiological follow-up, 21 were deceased, 36 refused to participate and 14 could not be traced.

The mean age was 60 y (15–93 y), the mean follow up was 44 months (15–78 m.); 28 were women, 16 men.

The fractures were classified according the Neer-classification but also according the different types of surgery they underwent: percutaneous or retrograde pinning without opening the fracture site, osteosynthesis with plate and screws, osteosynthesis with screws alone, bone-graft and osteosutures or a combination of two or more methods.

Two-part fractures (10 out of 13 fractures), but also 9 of the 15 three-part fractures, were treated by pinning, whereas the remaining 2 and 3-part, the isolated fractures of tuberculi and two 4-part fractures needed open surgery and fixation. A plate was used in only 3 cases, screws alone in 6 cases, a cortical bone-graft with osteosutures in 4 cases and a combination of open fixation in 8 cases. Whenever possible a minimal invasive technique was thus preferred.

16 patients (35,7%) had complications: 6 were minor (pin migration, slight secondary displacement or impingement as a consequence of protruding hardware), but one non-union, 4 CRPS and 5 avascular necrosis occurred. Only one of the latter underwent shoulder-arthroplasty at time of review. Major complications occurred mainly in the more complex fracture types (3 or 4 part fractures)

Mean values of Constant score, ASES-score, Neerscore, UCLA score and Simple Shoulder test were not statistically different, neither between fracture types nor between surgical techniques. Using a correlation analyses we found a negative correlation between age and scoring systems: the older the patient, the lower the score. Patient satisfaction was higher in the percutaneous or retrograde pinning group than the other types of open surgery.

We can conclude that although no statistical differences could be observed in our series, minimal invasive surgical techniques, less prone to complications, are preferable in the treatment of two and three part fractures of the proximal humerus and 4-part fractures of the younger population.

Purpose of the study: A multicentric study involving ten centres of shoulder surgery collected a retrospective series of 45 patients treated for infection of a total shoulder arthroplasty.

Material and methods: Mean age was 68 years (range 28–88) with 2/3 male. The initial indication was excentred joint degeneration (37%), centred degeneration (5%), necrosis (7%), fracture (34%), excentration without degeneration (12%), rheumatoid disease (5%). The implants were a reversed total prosthesis (59%), a hemiprosthesis (26%), a total anatomic prosthesis (15%). Nineteen patients (46%) had a ‘naive’ shoulder at implantation of the first prosthesis, including 70% without any specific medical condition: 30% fracture (hemiprosthesis) and 50% reversed total prosthesis.

Results: The infection developed immediately after implantation in 76% of the shoulders (abnormal pain, hematoma, early collection, inflammatory scar, early fistula). The preoperative Constant score (26 points) showed pain at 4, function at 8, mobility at 12, and force at 2. Osteolysis was noted in 30%. The infection lasted less than 3 months before revision in 27%, 3 to 12 months in 68%, and more than 12 months in 5%. Blood tests were normal in two patients. Staphylococcus epidermidis was isolated in 29%, Propioni bacterium acne in 31%, and these two germs in 5%, but no germ was identified in 24%. There was no loosening in 69% of the cases, making the revision invasive. A one-phase procedure was performed in 31% of patients and a two-phase procedure in 25%. Repeated wash-outs were performed in 25%. A reversed prosthesis was implanted at revision in 87% of the shoulders. These revisions produced a 22% complication rate and 27% were revised for repeated wash-outs, instability or definitive en bloc resection. An infectious disease specialist was called in for 75% of patients; a two-drug i.v. regimen for 10 days was instituted followed by oral antibiotics for 3 months. Outcome was assessed with more than 24 months follow-up for 26 patients. The Constant score at review was 47 points (pain 12, function 12, mobility 20, force 4).

Discussion: Seventy-seven percent of the patients were considered cured at more than 2 years. The two-phase surgery, undertaken when the infection had lasted 3 to 12 months (40%) or more than 12 months (60%), gave a Constant score at 51% and 100% cure. The one-phase option undertaken for infections lasting less than 3 months (40%) or 3 to 12 months (60%) gave a Constant score at 46% and 50% cure. Simple wash-out required 60% revision (repeated wash-out, or implant replacement) and 67% cure. In the event of complications after revision, the cure rate was 67%. In all, only 6% of the patients were dissatisfied.

Introduction: Minimally invasive surgery (MIS) has recently been proposed for unicompartmental arthroplasty to allow quick function recovery. The purpose of this study is to evaluate retrospectively the indications in which this technique would have been possible and successful.

Methods: The requirements for the minimal invasive technique are: a pre-operative flexion of 100° and a lesion limited to one compartment of the knee. The preoperative status, operative findings and clinical outcome of 160 cases of unicompartmental knee arthroplasty (MG, Zimmer) were analyzed to determine whether the criteria for MIS would have been possible.

Results: Preoperatively 12 knees had a flexion less than 100°. Postoperatively four of them had a limited flexion ranging from 90° to 100°. In 53 knees (33 %), peripheral osteophytes were removed on the opposite tibiofemoral joint. None of them were revised for progression of osteoarthritis. In 33 knees (21 %) a patelloplasty was associated to the procedure for peripheral osteophytes. Two of them were revised at 12 and 20 months for osteoarthritis progression.

Discussion: Removal of peripheral osteophytes can be successfully associated to the unicompartmental procedure when using a conventional surgical approach. In 96 of the 160 knees (60 %) MIS was not recommended either for limited preoperative flexion or for peripheral osteophytes. In 2 knees unicompartmental arthroplasty itself was not the correct indication and total knee arthroplasty would have been the right solution. Finally, in 62 of the 160 knees (39 %) unicompartmental arthroplasty using MIS was indicated. In conclusion unicompartmental knee arthroplasty may be either performed by conventional or minimal approach based on the preoperative clinical and radiological evaluation.

Conflict in Afghanistan demonstrated predominantly lower extremity and pelvi-perineal trauma secondary to Improvised Explosive Devices (IEDs). Mortality due to pelvic fracture (PF) is usually due to exsanguination. This study group comprised 169 military patients who sustained a PF and lower limb injury. There were 102 survivors and 67 fatalities (39% mortality). Frequent fracture patterns were a widened symphysis (61%) and widening of the sacroiliac joints (SIJ) (60%). Fatality was 20.7% for undisplaced SIJs, 24% for unilateral SIJ widening and 64% fatality where both SIJs were disrupted, demonstrating an increase in fatality rate with pelvic trauma severity. A closed pubic symphysis was associated with a 19.7% mortality rate versus 46% when widened. Vascular injury was present in 67% of fatalities, versus 45% of survivors. Of PFs, 84% were associated with traumatic amputation (TA) of the lower limb. Pelvic fracture with traumatic lower limb amputation presents a high mortality. It is likely that the mechanism of TA and PF are related, and flail of the lower limb(s) is the current hypothesis. This study prompts further work on the biomechanics of the pelvic-lower limb complex, to ascertain the mechanism of fracture. This could lead to evidence-based preventative techniques to decrease fatalities.

Aims. This aim of this study was to analyze the detection rate of rare pathogens in bone and joint infections (BJIs) using metagenomic next-generation sequencing (mNGS), and the impact of mNGS on clinical diagnosis and treatment. Methods. A retrospective analysis was conducted on 235 patients with BJIs who were treated at our hospital between January 2015 and December 2021. Patients were divided into the no-mNGS group (microbial culture only) and the mNGS group (mNGS testing and microbial culture) based on whether mNGS testing was used or not. Results. A total of 147 patients were included in the no-mNGS group and 88 in the mNGS group. The mNGS group had a higher detection rate of rare pathogens than the no-mNGS group (21.6% vs 10.2%, p = 0.016). However, the mNGS group had lower rates of antibiotic-related complications, shorter hospital stays, and higher infection control rates compared with the no-mNGS group (p = 0.017, p = 0.003, and p = 0.028, respectively), while there was no significant difference in the duration of antibiotic use (p = 0.957). In culture-negative cases, the mNGS group had lower rates of antibiotic-related complications, shorter hospital stays, and a higher infection control rate than the no-mNGS group (p = 0.036, p = 0.033, p = 0.022, respectively), while there was no significant difference in the duration of antibiotic use (p = 0.748). Conclusion. mNGS improves detection of rare pathogens in BJIs. mNGS testing reduces antibiotic-related complications, shortens hospital stay and antibiotic use duration, and improves treatment success rate, benefits which are particularly evident in culture-negative cases. Cite this article: Bone Joint Res 2024;13(8):401–410

Aims. Osteoarticular reconstruction of the distal femur in childhood has the advantage of preserving the tibial physis. However, due to the small size of the distal femur, matching the host bone with an osteoarticular allograft is challenging. In this study, we compared the outcomes and complications of a resurfaced allograft-prosthesis composite (rAPC) with those of an osteoarticular allograft to reconstruct the distal femur in children. Methods. A retrospective analysis of 33 skeletally immature children with a malignant tumour of the distal femur, who underwent resection and reconstruction with a rAPC (n = 15) or osteoarticular allograft (n = 18), was conducted. The median age of the patients was ten years (interquartile range (IQR) 9 to 11) in the osteoarticular allograft group and nine years (IQR 8 to 10) in the rAPC group (p = 0.781). The median follow-up of the patients was seven years (IQR 4 to 8) in the osteoarticular allograft group and six years (IQR 3 to 7) in the rAPC group (p = 0.483). Limb function was evaluated using the Musculoskeletal Tumor Society (MSTS) score. Results. At final follow-up, the knee was unstable in 9/18 patients (50%) in the osteoarticular allograft group and 2/15 patients (13%) in the rAPC group (p = 0.026). The median range of motion (ROM) of the knee was 117° (IQR 115° to 120°) in the osteoarticular allograft group and 100° (IQR 95° to 105°) in the rAPC group (p < 0.001). The median MSTS score was 25 (IQR 23 to 26) in the osteoarticular allograft group and 28 (IQR 26 to 29) in the rAPC group (p = 0.007). Osteoarthritic change was detected in 11/18 patients (61%) in the osteoarticular allograft group and in 4/15 (26%) patients in the rAPC group (p = 0.048). Conclusion. In our series, a resurfaced allograft-prosthesis composite provided better knee stability and function, with a lower rate of osteoarthritis; an osteoarticular allograft was associated with better knee ROM. Cite this article: Bone Joint J 2022;104-B(10):1174–1179

Aims. Distraction osteogenesis with intramedullary lengthening devices has undergone rapid development in the past decade with implant enhancement. In this first single-centre matched-pair analysis we focus on the comparison of treatment with the PRECICE and STRYDE intramedullary lengthening devices and aim to clarify any clinical and radiological differences. Methods. A single-centre 2:1 matched-pair retrospective analysis of 42 patients treated with the STRYDE and 82 patients treated with the PRECICE nail between May 2013 and November 2020 was conducted. Clinical and lengthening parameters were compared while focusing radiological assessment on osseous alterations related to the nail’s telescopic junction and locking bolts at four different stages. Results. Osteolysis next to the telescopic junction was observed in 31/48 segments (65%) lengthened with the STRYDE nail before implant removal compared to 1/91 segment (1%) in the PRECICE cohort. In the STRYDE cohort, osteolysis initially increased, but decreased or resolved in almost all lengthened segments (86%) after implant removal. Implant failure was observed in 9/48 STRYDE (19%) and in 8/92 PRECICE nails (9%). Breakage of the distal locking bolts was found in 5/48 STRYDE nails (10%) compared to none in the PRECICE cohort. Treatment-associated pain was generally recorded as mild and found in 30/48 patients (63%) and 39/92 (42%) in the STRYDE and PRECICE cohorts, respectively. Temporary range of motion (ROM) limitations under distraction were registered in 17/48 (35%) segments treated with the STRYDE and 35/92 segments (38%) treated with the PRECICE nail. Conclusion. Osteolysis and periosteal reaction, implant breakage, and pain during lengthening and consolidation is more likely in patients treated with the STRYDE nail compared to the PRECICE nail. Temporary ROM limitations during lengthening occurred independent of the applied device. Implant-related osseous alterations seem to remodel after implant removal. Cite this article: Bone Joint J 2023;105-B(1):88–96

The aim of this study was to analyze the frequency and reveal the most common reasons of the endoprosthetic instability in patients with malignant bone tumors. From 1992 – 2008, 625/515 patients, endoprosthetic replacement of major joints were performed. The median age of the patients was 30.3 years (13 to 72 years).

Aseptic instability was observed after 3/71(4.2%) humeral joint replacement out of total operations at this location, after 4/80 (5%) hip prosthesis, after 19/133 (14%) proximal tibial prostheses, after 44/299 (14.7%) distal femoral prostheses and after 2/37 (5.4%) total femur replacements.

The retrospective analyses has shown that the reasons of instability were the following: aseptic loosening of the stems of endoprosthesis in 26 cases (24.4%), stem break in 31 (36.1%), endoprosthetic unit destruction in 10 (11.6%), untwistment of fixational screws in 10 (11,6%), migration of hip endoprosthesis components in 2 (2.3%) and endoprosthesis dislocation in 12 (14%). The timing of endoprosthetic instability ranged from 7 days to 12.2 years (average 26.2 months). Statistic analyses was performed in a group of patients with aseptic endoprosthesis instability developed after proximal tibia and distal femur resection.

We conclude that the most frequent reason of aseptic instability was endoprosthetic stem break. The instability rate was actually lower among the patients who had underwent 5–10cm distal tibia resection comparing with the group of 10–15cm bone mass resection (p=0.05). Femoral resection enhanced the instability frequency comparing with proximal tibia resection in the group of 5–10cm bone mass resection (p=0.05).

Aims. The purpose of this study was to assess the prevalence of depression and anxiety symptoms in patients undergoing shoulder surgery using the National Institutes of Health (NIH) Patient-Reported Outcomes Measurement Information System (PROMIS) Depression and Anxiety computer adaptive tests, and to determine the factors associated with more severe symptoms. Additionally, we sought to determine whether PROMIS Depression and Anxiety were associated with functional outcomes after shoulder surgery. Methods. This was a retrospective analysis of 293 patients from an urban population who underwent elective shoulder surgery from 2015 to 2018. Survey questionnaires included preoperative and two-year postoperative data. Bivariate analysis was used to identify associations and multivariable analysis was used to control for confounding variables. Results. Mean two-year PROMIS Depression and Anxiety scores significantly improved from preoperative scores, with a greater improvement observed in PROMIS Anxiety. Worse PROMIS Depression and Anxiety scores were also significantly correlated with worse PROMIS Physical Function (PF) and American Shoulder and Elbow Surgeons scores (ASES). After controlling for confounding variables, worse PROMIS Depression was an independent predictor of worse PROMIS PF, while worse PROMIS Anxiety was an independent predictor of worse PROMIS PF and ASES scores. Conclusion. Mean two-year PROMIS Depression and Anxiety scores improved after elective shoulder surgery and several patient characteristics were associated with these scores. Worse functional outcomes were associated with worse PROMIS Depression and Anxiety; however, more severe two-year PROMIS Anxiety was the strongest predictor of worse functional outcomes. Cite this article: Bone Joint J 2022;104-B(4):479–485

Recent NICE guidelines suggest that Total Hip Arthroplasty (THA) be offered to all patients with a displaced intracapsular neck of femur fracture who: are able to walk independently; not cognitively impaired and are medically fit for the anaesthesia and procedure. This is likely to have significant logistical implications for individual departments.

Data from the National Hip Fracture Database was analysed retrospectively between January 2009 and November 2011. The aim was to determine if patients with displaced intracapsular neck of femur fractures admitted to a single tertiary referral orthopaedic trauma unit received a THA if they met NICE criteria. Case notes were then reviewed to obtain outcome and complication rates after surgery.

Five hundred and forty-six patients were admitted with a displaced intracapsular neck of femur fracture over the described time period. Sixty-five patients met the NICE criteria to receive a THA (mean age 74 years, M:F = 16: 49); however, 21 patients had a THA. The other patients received either a cemented Thompson or bipolar hemiarthroplasty. Within the THA cohort there were no episodes of dislocation, venous thromboembolism, significant wound complications or infections that required further surgery. Within the hemiarthroplasty cohort there was 2 mortalities, 2 implant related infections, 1 dislocation and 2 required revision to a THA.

There is evidence to suggest better outcomes in this cohort of patients, in terms pain and function. There is also a forecasted cost saving for departments, largely due to the relative reduction in complications. However, there were many cases (44) in our department, which would have been eligible for a THA, according to the NICE guidelines, who received a hemiarthroplasty. This is likely a reflection of the increased technical demand, and larger logistical difficulties faced by the department. We did note more complications within the hemiarthroplasty group, however, the numbers are too small to address statistical significance, and a longer follow up would be needed to further evaluate this. There is a clear scope for optimisation and improvement of infrastructure to develop time and resources to cope with the increased demand for THA for displaced intracapsular neck of femur fractures, in order to closely adhere to the NICE guidelines.

Aims. Clear cell sarcoma (CCS) of soft-tissue is a rare melanocytic subtype of mesenchymal malignancy. The aim of this study was to investigate the clinical and therapeutic factors associated with increased survival, stratified by clinical stage, in order to determine the optimal treatment. Methods. The study was a retrospective analysis involving 117 patients with histologically confirmed CCS, between July 2016 and November 2017, who were enrolled in the Bone and Soft Tissue Tumour Registry in Japan. Results. The five- and ten-year survival rates were 41% (95% confidence interval (CI) 29 to 52) and 37% (95% CI 25 to 49), respectively. On multivariable analysis, the size of the tumour of > 10 cm (p = 0.006), lymph node metastasis at the time of diagnosis (p < 0.001), distant metastases at the time of diagnosis (p < 0.001), and no surgery for the primary tumour (p = 0.019) were independently associated with a poor survival. For N0M0 CCS (n = 68), the development of distant metastases was an independent prognostic factor for survival (early (< 12 months), hazard ratio (HR) 116.78 (95% CI 11.69 to 1,166.50); p < 0.001; late (> 12 months), HR 14.79 (95% CI 1.66 to 131.63); p = 0.016); neoadjuvant/adjuvant chemotherapy (p = 0.895) and/or radiotherapy (p = 0.216) were not significantly associated with survival. The five-year cumulative incidence of local recurrence was 19% (95% CI 8 to 35) and the size of the tumour was significantly associated with an increased rate of local recurrence (p = 0.012). For N1M0 CCS (n = 18), the risk of mortality was significantly lower in patients who underwent surgery for both the primary tumour and lymph node metastases (HR 0.03 (95% CI 0.00 to 0.56); p = 0.020). For M1 CCS (n = 31), excision of the primary tumour was independently associated with better survival (HR 0.26 (95% CI 0.09 to 0.76); p = 0.013). There was no significant difference in survival between the different types of systemic treatment (p = 0.523). Conclusion. Complete excision of the primary tumour and lymph nodes is associated with a better survival in patients with CCS. Systemic treatment appears to provide limited benefits, demonstrating a pressing need for novel systemic agents. Cite this article: Bone Joint J 2023;105-B(11):1216–1225

Introduction

Local recurrence of Giant cell tumours of bone (GCT) is considered the main complication of surgical treatment (50%). Intra-lesional curettage with adjuvants like phenol or polymethylmethacrylate (PMMA) is recommended as initial treatment, decreasing the risk of recurrence. However, risk factors for local recurrence in skeletal GCT have not yet been firmly established and a golden standard for treatment remains controversial.

Aim of this study is identification of risk factors for recurrence in GCT, specifically after intra-lesional curettage with or without adjuvants.

Objective

To evaluate functional and oncological outcomes following sacral resection

A retrospective review of 51 consecutive patients undergoing fixation of Scaphoid fractures by two surgeons in a single institution was conducted. Twenty-four patients were treated with a Herbert screw and twenty-seven with an Acutrak screw. This included six patients who underwent acute fixation, three in each group. The remaining cases were for the treatment of non-union and delayed union.

There were no significant differences between the two groups in terms of age, side of injury, and mechanism of injury. Fractures were classified as proximal, middle and distal thirds of the Scaphoid and there was no significant difference between the groups regarding the types of fractures treated. The only significant difference between the groups was the time from injury to fixation when considering the cases of delayed union and non union which was greater in the Herbert screw group (7.5 months vs 4 months p=<0.05).

There was no significant difference in outcome between the two methods of fixation. Union rates for all cases were 79% for Herbert screws and 81% for Acutrak screws and 82% and 83% respectively when only considering the delayed union/non-union procedures. There was no difference in terms of time to union, further surgery or clinical outcome between the two groups. The Acutrak screw required removal in five patients and the Herbert screw in two due to symptoms from screw prominence. This was not statistically significant.

In conclusion there is no significant difference in surgical outcome between these two methods of fixation for Scaphoid fractures. The authors feel that this supports the view that biological factors are more important than the method of fixation in obtaining union of Scaphoid fractures.

Bone marrow edema is a common cause of pain of the locomotor apparatus. We reviewed 50 patients (28 male, 22 female) with bone marrow edema of the knee. The patients mean age was 56.2 12.8 years. 8 cases were estimated to have an idiopathic BME, 10 posttraumatic and the other 32 ones to be secondary to an activated osteoarthritis or to mechanic stress. Iloprost is a vasoactive prostacyclin analogue. Therapy consisted of a series of five infusions with either 20 or 50g of iloprost given over 6 hours on 5 consecutive days each. Pain at rest as well as under stress were assessed with a semi quantitative scale from before and 4 months after therapy. MRI investigations were done before and repeated 4 months after therapy.

At the clinical follow-up 4 months after therapy, pain level at rest had diminished 84% (p < 0.0001). 70% of patients referred about a reduction, 30% about no change. Pain under stress decreased 57%, (p < 0.0001). 76% of patients showed lower pain under activity, 24% no change from baseline. There was no increase of pain level in any patient. In MRI in 85% a significant reduction of the BME size or complete restitution could be observed, 15% showed no change. Response rate to iloprost infusions came to 100% in idiopathic, 100% in posttraumatic and 66% in secondary BME. A significant reduction of side effects could be reached by lowering the daily dosage from 50 to 20g.

The authors conclude that parenteral application of iloprost might be a viable method in the treatment of BME of different origins.

Purpose: Isolated tumours of the peripheral nerves are exceptional and benign in 90% of the cases. They develop from the constitutive elements of the nerve and correspond to schwannomas in 80% of cases. Other tumours are much more rare and exhibit wide histological variability.

Material and methods: Fifty-one patients were reviewed at mean 4.6 years. Forty-one had a resectable tumour: schwannoma (n=39), intranervous lipoma (n=2). Ten an unresectable tumour: solitary neurofibroma (n=5), peri-nervous hemangioma (n=3), neurofibrolipoma (n=2). We detailed the type of lesion, diagnostic elements, and results of complementary explorations. Enucleation was performed for resectable tumours. Epineurotomy for decompression with systematic interfascicular biopsy was performed in the event of an unresectable tumour.

Results: Postoperative neurological deficits were exceptional and transient. In a first case, prognosis was excellent due to the absence of recurrence or degeneration. In the second, neurological disorders persisted but decreased (paraesthesia). The course remained stable.

Discussion: Our findings are in line with reports in the literature. The diagnosis of nerve tumour should be entertained in the event of tumefaction along a nerve trajectory or if palpation triggers pain. MRI is the most powerful complementary exploration, particularly for deep tumours. The nature of the tumour, its benignity, and the possibility for resection can be suspected on the basis of clinical and complementary findings, but surgery and pathology examination of the surgical specimen are required for confirmation. Preservation of nerve continuity is the key to the therapeutic approach. For resectable tumours, exceptional persistence of symptoms should be followed by a new exploration to search for small unrecognised tumour(s) at the same operative site. For all other cases, recent and rapid changes in the clinical presentation is a sign of recurrence and requires appropriate intervention. To our knowledge, malignant degeneration has never been observed.

Conclusion: First-intention resection of a nerve with a nerve tumour is never indicated.

Purpose

This report compares midterm results of open neck osteoplasty + neck osteotomy vs arthroscopic osteoplasty for severe Slipped Capital Femoral Epiphysis (SCFE).

Purpose: Aim of this study was to analyse our Institution experience with osteosarcoma in Paget’s disease (PD).

Methods: Twenty-six patients treated between 1961 and 2006 were retrospectively analysed. Information focusing on treatment, imaging and oncologic outcome were obtained from clinical charts.

Results Fifteen patients had previous diagnosis (mean time 9 yrs) of monostotic (80%) or polyostotic (20%) PD; in 11 sarcoma and PD were contemporarily diagnosed. The most frequents osteosarcoma histotypes observed were osteoblastic in 18 cases (69%), fibroblastic in 5 cases (19%), teleangectasic in 2 patients and chondroblastic in one case. In 6 patients surgery only was performed: 3 amputations and 3 resections. In 3 pts surgery (amputation), adjuvant chemotherapy and radio-therapy were given. In 1 pt surgery (amputation) and radiotherapy. In 12 patients surgery and chemotherapy: adjuvant in 10 cases (8 amputations and 2 resections) and neoadjuvant in 2 (both amputations). Two patients had only radiotherapy and 2 had only chemotherapy. Oncologic outcome showed 4 pts with no evidence sisease at a mean follow up of 139 months (min.42.6, max.257.4) and 22 died with disease at a mean time of 20.15 months (min.1, max. 84). One patient only of 6 (11%) treated with surgery only is NED at 10 years, while the other 5 died from disease at a mean time of 30 mos. Three of 12 patients (25%) treated with surgery and chemotherapy are NED at a mean follow up of 12 years, while 9 died of disease at a mean time of 24 months. All patients treated without surgery died at of 7.5 mos on average (min.1 – max.13.7).

Conclusions: Sarcomas in PD have a poor prognosis in pts treated without surgery or with surgery only. Surgery with chemotherapy – when feasible – improves prognosis.

Purpose: Nonunion of the tibia is a therapeutic challenge requiring a good understanding of bone healing, bone substance loss and skin trophicity disorders. The fibula pro tibia Huntington procedure consists in transposing the homolateral fibula onto the injured tibia. This allows bridging the bone defect, realignement and stabilisation of the nonunion segment.

Material and methods: This retrospective series included eleven patients (ten men and one woman), mean age 32 years (16–62). The cause of the injury was a traffic accident in six cases, defenestration in one, adamatinoma in one and osteomyelitis in one. The skin was broken in nine patients with septic nonunion in seven. Mean follow-up was 13 years (1–21).

Results: Mean delay to healing was 10.5 months (8.5 for post-traumatic nonunions) and was achieved in eight cases. A higher tibial nonunion persisted after resection of an adamantinoma measuring 22 cm and two patients had to be amputated in a context of acute suppuration. Walking without crutches was possible for eight patients whose tibia had healed and the mean pain score was 2 / 10.

Discussion: Several solutions can be proposed for patients with a tibial nonunion. The inter-tibiofibular graft requires a large bone graft in patients who have already had several operations. Th Papineau method only provides cancellous bone which is mechanically weak. The Ilizarov method can allow bone transfer and dynamisation of the nonunion with compression distraction. Microanastomosis transfers using a free fibula require a trained team with the risk of potential infection of the anastomoses in these infected patients. The Huntington method has the advantage of providing osteosynthesis without the inconvenients of inert material. The fibular acts like a biological plate with good vascularisation and stability to realign and lengthen the tibial segment.

Conclusion: This surgical technique is a supplementary therapeutic means for treating (septic) nonunion of the tibia. It is easy to perform and may be the last salvage method. The advantages are: a solid compact graft fixed in the mechanical axis of the tibia, possibility of bridging bone loss of more than 28 cm, short operative time without risk of complications related to graft harvesting, shorter hospital stay.

Introduction: The Scarf osteotomy for the treatment of hallux valgus is achieving popularity, but no comparative study has proven the efficacy of this procedure over other first metatarsal osteotomies.

We present a retrospective comparative review of the radiological outcomes of Chevron and Scarf with Akin osteotomy in the treatment of hallux valgus.

Materials and Methods: The radiological outcomes of 40 first metatarsal osteotomies, 20 Chevron and 20 Scarf with Akin are presented. The radiological parameters studied included hallux valgus angle, hallux inter-phallangeus, intermetatarsal angle, sesamoid station and foot width.

Results: The mean post-operative hallux valgus angles (HVA’s) were: Chevron mean HVA 17.90, standard deviation 7.360, standard error 1.65. Scarf with Akin osteotomy mean HVA 9.550, standard deviation 6.60, standard error 1.4. The difference in postoperative HVA between the two operations was statistically significant (p< 0.001).

The mean post-operative intermetatarsal angles (IMA) were: Chevron mean 8.050, standard deviation 2.560, standard error 0.57. Scarf with Akin mean 7.220, standard deviation 2.56, standard error 0.57. The difference in postoperative IMA between the two groups did not achieve statistical significance.

The mean change in IMA for each was: Chevron mean increment 4.90 Standard deviation 2.290, standard error 0.51. Scarf with Akin mean increment 6.680, standard deviation 4.130, and standard error 0.88. The difference in alteration of IMA between the two groups did not achieve statistical significance.

Discussion and Conclusion: We conclude that as there was no difference in the distribution of post-op IMA for Scarf and Chevron osteotomies that the added affect of an Akin osteotomy may contribute to the Scarf to produce the better correction in hallux valgus angle.

Of the 6075 patients enrolled in EU-CORE registry, 206 patients had orthopaedic device-related infections. Significant underlying diseases were reported in 71% patients, most frequently cardiovascular disease (38%). The common sites of infection were knee (40%) and hip (33%). Among the 170 patients with available culture results, 135 (79%) were positive. Coagulase-negative staphylococci (CoNS, 44%) and Staphylococcus aureus (43%, of those 47% were methicillin resistant) were the most commonly isolated pathogens. Daptomycin was used empirically in 48% patients and as second-line therapy in 67% patients. During daptomycin therapy, 67% patients had undergone surgery (debridement, 61%; removal of foreign device, 39%; incision and drainage, 9%). Over half of the inpatients (54%) received concomitant antibiotics. Daptomycin was most frequently prescribed at a dose of 6 mg/kg/day (48%), with a median duration of therapy of 16 (range, 1–176) days. The overall clinical success rate was 85%, and was similar whether daptomycin was administered as first- or second-line therapy. The success rates achieved for infections caused by S. aureus and CoNS were 86% and 83%, respectively. Among the 79 patients who entered the long-term follow-up, 85% had a sustained response. Adverse events (AEs) and serious AEs possibly related to daptomycin were reported in 4.4% and 1.9% patients, respectively.

Results from this real-world clinical experience showed that daptomycin is an effective and well-tolerated treatment option for orthopaedic device-related infections with a high success rate up to 2 years of follow-up.

Purpose of the study: Completely arthroscopic repair of rotator cuff tears is widely considered as the standard treatment. We reviewed a multicentric retrospective series of patients.

Material and methods: This series of arthroscopic repairs of full-thickness tears of the supraspinatus and infraspinatus were assess with the Constant score together with arthroMRI or arthroscan at one year follow-up at least. Data were analyzed with SPSS10. The series included 576 patients who underwent surgery from January 2001 to June 2003. Mean age was 57.7 years, 52% males and 60% manual laborers. Mean preoperative Constant score was 46.4/100 (r13.4). The tear was limited to the supraspinatus in 69% of patients with extension to the upper third of the infraspinagus for 23.5% and to all tendons for 7.5%. The supraspinatus tear was distal in 41.7% of patients, intermediary for 44%, and retracted for 14.3%. Arthroscopic repair was performed in all cases, with locoregional anesthesia for 60.9%. Implants were resorbable for 33% and metallic for 62.1%. Acromioplasty was performed for 92.7% and capsulotomy for 14.9%.

Results: The mean subjective outcome was scored 8.89/10. The Constant score improved from 46.3±13.4 to 82.7±10.3 with 62% of patients being strictly pain free. The force score improved from 8.5±3.7 to 13.6±5.4. Outcome was excellent or very good for 94% of the shoulders at 18.5 mean follow-up. The rate of complications was 6.2% with 3.1% of patients presenting prolonged joint stiffness, 2.7% reflex dystrophy, 0.2% infection and 0.2% implant migration. The cuff was considered normal in 55.7% of the shoulders with an intratendon addition image for 19%, i.e. 74.7% non-torn cuffs. A point leakage was noted in 9.5% with pronounced leakage in 15.7%, i.e. 25.2% recurrent tears.

Discussion and conclusion: The functional outcome obtained after arthroscopic repair of rotator cuff tears is good. Arthroscopy has the advantage of a low rate of complications yet provides good clinical and anatomic results. Age is correlated with functional outcome and healing, but should not be considered as a contraindication.

Purpose of the study: The appropriate treatment for Legg-Perthes-Calvé disease (LPCd) remains a subject of debate. Certain teams consider orthopedic treatment adequate. Others advocate surgery to improve prognosis. Is surgery necessary? When is the proper time? We reviewed retrospectively 91 surgically treated hips (Salter osteotomy or triple pelvis osteotomy) at the end of growth.

Material and methods: Among 485 hips with LPCd, 349 (71.9%) presented massive involvement (Catterall 3 and 4, Herring B and C, Salter B). Ninety-one patients with severe disease were reviewed at the end of growth. Complementary explorations included magnetic resonance imaging, scintigraphy and arteriography using the Dias protocol which enables an assessment of the excentration and the femoral head deformation and identifies hips at risk. Surgical treatments were Salter osteotomy (SA) or triple osteotomy (TO). Three groups were identified depending on the age at disease diagnosis: less than 5 years, 5–9 years, more than 9 years. Using the Stulberg and Mose classifications, outcome was considered good (Stulberg 1 and 2, Mose good), fair (Stulberg 3, Mose fair), or poor (Stulberg 4 and 5, Mose poor).

Results: There were 50 Carttell 3, Herring B, Salter B hips and 41 Catterall 4, Herring B and C, Salter B hips (80% boys). Distribution by group of age at diagnosis was: 34 (37.4%) less than 5 years, 48 (52.7%) 6–9 years, 9 (9.9%) more than 9 years. Salter osteotomy was performed on 32 hips (35.2%) and triple pelvic osteotomy on 59 (94.8%). Outcome at end of growth was: less than 5 years Catterall 3: 77% good, 15.4% fair, 7.6% poor; Catterall 4: 52.4% good, 33.3% fair, 14.3% poor; 6–9 years: Catterall 3: 70% good, 20% fair, 10% poor; Catterall 4: 55.5% good, 22.2% fair, 22.2% poor; more than 9 years: Catterall 3: 42.9% good, 42.9% fair, 14.2% poor; Catterall 4: 50% good, 50% poor.

Conclusion: Outcome worsens with increasing age at diagnosis. Despite surgery, a spherical femoral head (Stulberg 1 or 2) is achieved in only one hip Catterall 4 hip out of two. This result is observed in Catterall 3 hips only in children whose diagnosis is established after the age of nine years. Prognosis is better in Catterall 3 hips.

Introduction: Prosthetic joint infections occur in 1–2 % following total knee replacement. Different options of treatment are described in literature with a lack of data from randomized, controlled trials.

We classified septic revision surgeries following total knee according to a classification published by Mc Pherson. Eradication rate of one stage versus two stage exchange was compared.

Materials and Methods: We included 74 patients who underwent septic revision surgeries following total knee replacement in the years 1998 to 2005. Gender distribution was 42 female and 32 male patients. The mean age at revision surgery was 71 years, at primary implantation mean 68,8 years.

Results: The eradication rate overall was 77 %, in one stage exchange 41.7% and in two stage procedures 86%. Multiple stage revision showed an eradication rate of 75%, necrectomy/debridement 50%, arthrodesis and amputation 100%.

Regarding Mc Pherson’s systemic grades classification the eradication rate for two stage exchanges was 85,7% in group A+B and 60%% in group C. One stage procedures achieved 0% eradication rate in group B and 60% in group C. Regarding Mc Pherson’s local extremity grade classification eradication rates within two stage revisions were 84% in group 2 and 75% in group 3. One stage revision achieved 40% and 0%.

Conclusion: Although two stage revision surgeries achieved better results regarding eradication rates then one stage revision surgery, results were statistically not significant. Reason could be a too small number of included patients for a significant statistical impact. The individual surgical procedure should orientate on the classification published by Mc Pherson.

Our aim was to determine the prevalence of shoulder symptoms in patients with type I compared to type 2 diabetes mellitus and evaluate the clinical presentation of patients diagnosed with adhesive capsulitis. This was a retrospective case-note review of 164 diabetic patients treated for shoulder symptoms from 1996 to 2007. Diabeta 3 for relevant Diabetic data. We used ANOVA, Tukey HSD, Chi-Square and Fisher’s Exact tests.

The incidence of treated shoulder patients in diabetic population: 1.04%. 86 males; 78 females. Average age 58 years (22 – 83). DM Type I 34% (46/136); Type II 66% (90/136). Mean duration of DM at presentation: 10 years (1–33). Mean HbA1c at presentation 8.3%. Retinopathy 16% (19/90); Neuropathy 12% (12/88).

The diagnoses were: Impingement 101 (62%); Adhesive Capsulitis 35 (21%); Cuff tear 17 (10%); Arthritis 11 (7%).

Mean recorded pre-treatment ROM: Impingement (flexion 117°, abduction 103°, ER 36°); Adhesive Capsulitis (flexion 90°, abduction 75°, ER 12°); Cuff tear (flexion 109°, abduction 95°, ER 45°); Arthritis (flexion 67°, abduction 93°, ER 18°).

Adhesive Capsulitis was significantly related to: HbA1c (9.9%); p< 0.001, Type I DM; p< 0.003, Duration of DM (average 17.5 yrs); p< 0.03.

An interesting statistically significant (p< 0.003) correlation was found between Type 2 DM and Impingement Syndrome.

Treatments included: Injection (53), MUA (49), Arthroscopy (99), Open Surgery (56). 82% patients satisfactorily discharged (mild/no pain and improved ROM: flexion > 150°, abduction > 150° and ER > 50°) after an average 3.4 months. Three referred to pain clinic, sixteen patients didn’t attend their follow-up appointment and seven died. Eleven relapsed (eight adhesive capsulitis).

Persistent symptoms were more common in Diabetic patients with adhesive capsulitis, which was found to be significantly related to Type I DM, its duration and control (HbA1c levels). Type II Diabetics are more likely to be affected with impingement syndrome. Close liaison with the Diabetology Department is essential for effective treatment of Diabetic Shoulder pathology.

Purpose: Several studies have been conducted to search for factors affecting the prognosis of osteosarcoma. In this work, we attempted to assess the prognostic value of the biopsy technique and initial management on long-term prognosis of localised osteosarcoma of the limbs.

Material and methods: The series included 139 patients (88 males and 51 females, aged 4 to 58 years) with high-grade malignant osteosarcoma of the lower limbs treated or followed by our team between 1984 and 1998. Seventy-eight patients were referred to our unit for biopsy performed by a team surgeon after careful search for local extension and conception of the future extratumour en bloc resection. The 84 other patients were referred to our team after biopsy or after induction chemotherapy. There was no statistical significant difference between the two groups for known prognostic factors (localisation, tumour size, gender). All patients were given pre- and postoperative chemotherapy using the protocols generally applied at the time of their treatment. Three referred patients had already undergone amputation. All others were treated with conservative surgery even in case of fracture, very large tumour or young age. Patients were followed by their surgeon and chemotherapist independently with regular visits every three months for two years then every six months for two years and every year thereafter. Median follow-up was ten years (2.5–16.5 years).

Results: There were 12 local relapses (9%). Two were complications observed among the 75 patients followed from the start in our unit and ten were among the 84 secondary referral patients. Relapse-free survival reached 54% (46/84) in the referral patients compared with 73% (40/55) for the patients initially treated in our unit. For patients treated initially in our unit after 1986, the relapse-free survival rate reached 93%. Multivariate analysis demonstrated that the difference was significant (p < 0.02).

Conclusion: Initial management by an experimented team is a major prognosis factor for long-term survival and for risk of local recurrence in patients with high-grade malignant osteosarcoma of the limbs first seen without metastasis. When the diagnosis of osteosarcoma cannot be ruled out, these patients should be referred to a team specialised in malignant bone tumours before biopsy.

The development of local recurrence after multimodal treatment of osteosarcoma is associated with a very poor prognosis. The importance of clear surgical margins has been demonstrated in multiple studies, however up to date there are no studies defining which margin width is safe from an oncological perspective. The purpose of this retrospective analysis was to evaluate whether margin width or other surgical and tumour-related factors influence the development of local recurrence in osteosarcoma patients. The files of 1867 consecutive patients with high-grade central osteosarcoma of the extremities, the pelvic bones and the shoulder girdle, who had achieved a complete surgical remission during combined-modality therapy on neoadjuvant Cooperative Osteosarcoma Study Group (COSS) protocols between 1986 and 2005, were reviewed. Of those, the data required were available for 1369 patients, who were the subject of this analysis. Eighty of these patients developed a local recurrence during the course of their illness. The median surgical margin width amounted to 45 mm (range, 0 to 140 mm) in the local recurrence (LR) group and 50 mm (range, 0 to 350 mm) in the non-local recurrence (NLR) group (p=0.106). No statistically significant difference between the two groups was found regarding tumour size (mean, 10.38 cm and 9.53 cm respectively, p=0.169), T-status (p=0.225) and presence of pathological fracture (p=0.231). However infiltration of the soft tissue beyond the periosteum was documented in 58.8% of the patients with local recurrence and only in 36.9% of the rest (p=0.003). Furthermore, in 50% of the LR group the biopsy had been performed in a centre other than the one performing the definitive tumour resection, compared to 30.2% of the NRL group (p=0.001). In conclusion, the absolute metric width of surgical margins does not define oncological safety. Local recurrence is more likely to develop in patients with soft tissue infiltration beyond the periosteum or those biopsied in a centre other than the one performing the tumour resection

We report our experience in 42 patients, using corticocancellous bone grafts and lag screw fixation for un-united scaphoid fractures. Using a grading system, we analysed the suitability of the method for three types of nonunion. We recommend the operation for the treatment of scaphoid nonunion, except where there is avascular necrosis of the proximal pole.

Aims. Vertebral body tethering (VBT) is a non-fusion technique to correct scoliosis. It allows correction of scoliosis through growth modulation (GM) by tethering the convex side to allow concave unrestricted growth similar to the hemiepiphysiodesis concept. The other modality is anterior scoliosis correction (ASC) where the tether is able to perform most of the correction immediately where limited growth is expected. Methods. We conducted a retrospective analysis of clinical and radiological data of 20 patients aged between 9 and 17 years old, (with a 19 female: 1 male ratio) between January 2014 to December 2016 with a mean five-year follow-up (4 to 7). Results. There were ten patients in each group with a total of 23 curves operated on. VBT-GM mean age was 12.5 years (9 to 14) with a mean Risser classification of 0.63 (0 to 2) and VBT-ASC was 14.9 years (13 to 17) with a mean Risser classification of 3.66 (3 to 5). Mean preoperative VBT-GM Cobb was 47.4° (40° to 58°) with a Fulcrum unbend of 17.4 (1° to 41°), compared to VBT-ASC 56.5° (40° to 79°) with 30.6 (2° to 69°)unbend. Postoperative VBT-GM was 20.3° and VBT-ASC Cobb angle was 11.2°. The early postoperative correction rate was 54.3% versus 81% whereas Fulcrum Bending Correction Index (FBCI) was 93.1% vs 146.6%. The last Cobb angle on radiograph at mean five years’ follow-up was 19.4° (VBT-GM) and 16.5° (VBT-ASC). Patients with open triradiate cartilage (TRC) had three over-corrections. Overall, 5% of patients required fusion. This one patient alone had a over-correction, a second-stage tether release, and final conversion to fusion. Conclusion. We show a high success rate (95%) in helping children avoid fusion at five years post-surgery. VBT is a safe technique for correction of scoliosis in the skeletally immature patient. This is the first report at five years that shows two methods of VBT can be employed depending on the skeletal maturity of the patient: GM and ASC. Cite this article: Bone Jt Open 2022;3(2):123–129

Aims. The aim of this study was to determine the impact of hospital-level service characteristics on hip fracture outcomes and quality of care processes measures. Methods. This was a retrospective analysis of publicly available audit data obtained from the National Hip Fracture Database (NHFD) 2018 benchmark summary and Facilities Survey. Data extraction was performed using a dedicated proforma to identify relevant hospital-level care process and outcome variables for inclusion. The primary outcome measure was adjusted 30-day mortality rate. A random forest-based multivariate imputation by chained equation (MICE) algorithm was used for missing value imputation. Univariable analysis for each hospital level factor was performed using a combination of Tobit regression, Siegal non-parametric linear regression, and Mann-Whitney U test analyses, dependent on the data type. In all analyses, a p-value < 0.05 denoted statistical significance. Results. Analyses included 176 hospitals, with a median of 366 hip fracture cases per year (interquartile range (IQR) 280 to 457). Aggregated data from 66,578 patients were included. The only identified hospital-level variable associated with the primary outcome of 30-day mortality was hip fracture trial involvement (no trial involvement: median 6.3%; trial involvement: median 5.7%; p = 0.039). Significant key associations were also identified between prompt surgery and presence of dedicated hip fracture sessions; reduced acute length of stay and both a higher number of hip fracture cases per year and more dedicated hip fracture operating lists; Best Practice Tariff attainment and greater number of hip fracture cases per year, more dedicated hip fracture operating lists, presence of a dedicated hip fracture ward, and hip fracture trial involvement. Conclusion. Exploratory analyses have identified that improved outcomes in hip fracture may be associated with hospital-level service characteristics, such as hip fracture research trial involvement, larger hip fracture volumes, and the use of theatre lists dedicated to hip fracture surgery. Further research using patient level data is warranted to corroborate these findings. Cite this article: Bone Joint J 2021;103-B(10):1627–1632

Purpose of the study: Appropriate management of chronic sprains of the scapholunate joint remains a subject of debate. Different surgical techniques have been proposed, from partial arthrodesis of the carpus to ligamentoplasty. We opted for scaphocapitatum arthrodesis. The purpose of this report was to assess clinical and radiological outcome.

Material and methods: From 1997 to 2001, 13 arthrodeses (13 patients) were performed for this indication. The procedure involved two screws (n=11), one screw and stapling (n=1), and stapling alone (n=1). A free autologous graft was used in all cases. Mean patient age was 40 years (12 males and one female). These patients were victims of sports accidents (n=8) or occupational accidents (n=5). Mean follow-up was 26 months (range 24–31 months). Variables noted were joint mobility, pain, grasp force and pinch force. Wrist x-rays were used to measure the height of the carpus and the radio-lunate angle.

Results: A 31% loss in the radial inclination was noted as as a 14.5% loss in the ulnar inclination. Dorsal flexion of the wrist declined from 60° to 48°, palmar flexion from 47° to 28°. Stiffness mainly involved the radial inclination and palmar flexion. Grasp and Pinch forces improved (125° on average). All patients excep one presented residual pain. Six patients complained of pain only for efforts and six presented invalidating pain. Only seven patients were able to resume their occupational activity. There were three cases of nonunion which required revision to achieve final bone healing (poor outcome). Carpal height improved (0.47±0.54). The mean radiolunate angle at last follow-up was 11°. DISI persisted in only one wrist.

Discussion: This technique reduced wrist mobility. For all patients, the dorsal approach to the wrist produced inevitable stiffness. Radial inclination declines due to the intracarpal fusion. This arthrodesis enabled restitution of the carpal height and partially corrected for the DISI. This operation did not provide pain relief but did not alter the carpal x-ray. We raise the question of the pertinence of associating this type of arthrodesis with total denervation of the wrist.

Objective

To evaluate functional and oncological outcomes following sacral resection

To evaluate functional and oncological outcomes following resection of primary malignant bone tumours.

Primary malignant tumours of the sacrum are rare, arising from bony or neural elements, or bone marrow in haematological malignancies.

Management of these lesions is dictated by anatomical considerations and the behaviour of tumours. The three key issues which arise are the adequacy of tumour resection, mechanical stabilisation and the need for colostomy.

A retrospective review of the surgical management of primary malignant sacral tumours from 2004 - 2009.

The study included 46 patients (34 males, 12 females) with an average age of 49 (range 7 – 82). Median duration of symptoms before presentation was 26 months.

10 patients had inoperable tumours at presentation. 6 patients had chemotherapy. 2 patients opted for palliative radiotherapy. 1 patient was unfit for surgery.

25 patients (54%) underwent surgical resection. 8 underwent instrumented stabilisations with fibula strut graft vs. 17 uninstrumented.

Colostomy was performed in 10 patients (40%). Mean follow post-operatively was 19.0 months.

Wound healing problems were present in 5/25 (20%). There was no difference in infection rates between definitive surgery with and without colostomy. Mechanical failure of stabilisation was noted in 75%. There was one peri-operative death.

Local recurrence occurred in 12%(3/25) of operated patients although follow-up period was noted to be short.

Mechanical stabilisation for extensive lesions in the sacrum are particularly challenging in tumour surgery. Despite radiological failure in 7/8 instrumented stabilisations, patients were relatively asymptomatic and only 1/8 required revision stabilisation surgery.

Ethics approval: None: Audit Interest Statement: None

Time at the surgical ‘coal-face’ has been reduced by introduction of the European Working Time Directive (EWTD) significantly impacting training opportunity. Our null hypothesis was that duration of surgery is significantly longer if a trainee were performing the operation despite supervision or level of trainee experience.

Cemented hip hemiarthroplasty was chosen as our index procedure as complexity is largely comparable between cases. 461 patients were identified on the hospital trauma database. Data were augmented by information regarding level of surgeon, assistant and time of surgery from the hospital theatre database.

There was no significant difference in registrar and consultant operative times, mean time 69 and 72 minutes respectively. SHOs were significantly slower (mean 80 minutes, p=0.0006). Junior (ST5 or less) registrars were significantly slower (mean 81minutes, p=0.0002) whereas senior registrars were not. Supervision level had no effect on duration of senior registrar operations but when junior registrars were consultant supervised they were not significantly slower (mean 75 minutes, p=0.09).

Supervised operating therefore reduces time variability and should be promoted within a climate of training. Increase in mean operative time in registrars and SHOs is insignificant within a day's operating and is unlikely to lead to cancellations of cases.

Purpose: The purpose of this study was to analyse mechanical failures involving dismonted osteosynthesis materials implanted to fix pertrochanteric or subtrochanteric fractures with a dynamic hip screw (DHS), a Gamma nail, or a plate nail system (STACA).

Material and methods: Our cohort included 16 patients among a series of 350 patients who had been treated with 240 DHS, 80 Staca nailplates, and 30 Gamma nails between 1996 and 1999. We used the Ender classification for the x-ray analysis and the Cuny criteria which describe the most common causes of dismounted material.

Results: According to the defined criteria, 70/350 osteosynthesis assemblies (20%) were considered insufficient on the immediate postoperative x-rays and eventually dismounted in 16 patients. Two of these patients had major osteopaenia according to the Singh criteria and ten underwent revision because of poor clinical tolerance. These patients had six DHS (3 “swinging” cervical nails, two dismounted plates, and one screw protruding into the joint space). A protruding screw was the problem for the eight Staca nail-plates. Two Gamma nails had a “swinging” screw. These cases of dismounted material were predominantly observed in patients with Ender grade 5, 7 and 8 pertrochanteric fractures.

Discussion: Our analysis of these cases revealed several important factors: 1) the quality of the fracture reduction with restitution of the medial pillar of the per-trochanteric mass; 2) central anchoring in the femoral head essential for stable fixation; 3) superior stability of the DHS in grade 1 and 6 fractures due to the greater projected surface improving hold in cancellous bone. Inversely, for subtrochanteric fractures (grade 7 and 8), centromedulary shaft anchoring with a Gamma nail reduces mechanical stress in varus and thus the risk of “swinging” screws. Finally, the monoblock construct of the Staca nail-plate, which does not have the dynamic potential of the DHS and the Gamma nail, raises a risk of protrusion, particularly in case of “internal rotation” fractures with major metaphyseal comminution (grades 4 and 5). This latter type of fixation is however very effective for simple pertrochanteric fractures with minimal comminution (grades 1 to 3).

Conclusion: Material dismounting results from a series of factors related both to the material used and to the operative technique. We thus reserve the Staca nail-plate for grade 1 to 3 fractures in the Ender classification, the DHS for grades 1 to 6 and the nail-screw fixation for subtrochanteric (grade 7 and 8) fractures.

Aims. The new COVID-19 variant was reported by the authorities of the UK to the World Health Organization (WHO) on 14 December 2020. We aim to describe the clinical characteristics and nosocomial infection rates in major trauma and orthopaedic patients comparing the first and second wave of COVID-19 infection. Methods. A retrospective analysis of a prospectively collected trauma database was reviewed at a level 1 major trauma centre from 1 December 2020 to 18 February 2021 looking at demographics, clinical characteristics, and nosocomial infections and compared to our previously published first wave data (26 January 2020 to 14 April 2020). Results. From 1 December 2020 to 18 February 2021, 522 major trauma patients were identified with a mean age of 54.6 years, and 53.4% (n = 279) were male. Common admissions were falls (318; 60.9%) and road traffic accidents (RTAs; 71 (13.6%); 262 of these patients (50.2%) had surgery. In all, 75 patients (14.4%) tested positive for COVID-19, of which 51 (68%) were nosocomial. Surgery on COVID-19 patients increased to 46 (61.3%) in the second wave compared to 13 (33.3%) in the first wave (p = 0.005). ICU admissions of patients with COVID-19 infection increased from two (5.1%) to 16 (20.5%), respectively (p = 0.024). Second wave mortality was 6.1% (n = 32) compared to first wave of 4.7% (n = 31). Cardiovascular (CV) disease (35.9%; n = 14); p = 0.027) and dementia (17.9%; n = 7); p = 0.030) were less in second wave than the first. Overall, 13 patients (25.5%) were Black, Asian and Minority ethnic (BAME), and five (9.8%) had a BMI > 30 kg/m. 2. The mean time from admission to diagnosis of COVID-19 was 13.9 days (3 to 44). Overall, 12/75 (16%) of all COVID-19 patients died. Conclusion. During the second wave, COVID-19 infected three-times more patients. There were double the number of operative cases, and quadruple the cases of ICU admissions. The patients were younger with less dementia and CV disease with lower mortality. Concomitant COVID-19 and the necessity of major trauma surgery showed 13% mortality in the second wave compared with 15.4% in the first wave. In contrast to the literature, we showed a high percentage of nosocomial infection, normal BMI, and limited BAME infections. Cite this article: Bone Jt Open 2021;2(8):661–670

To determine the outcome of Clavicle Hook Plate fixation in terms of level of function achieved, healing of the fracture and the need for removal of the hook plate.

Review of patient records and radiographs of all the fractured clavicles and acromioclavicular dislocations that were surgically treated with a Clavicle Hook Plate. The study population was identified using the operating theatre data.

A total of 24 patients (19 lateral third-Neer type II-fractures and 5 type III acromioclavicular dislocations) were treated from January 1998 to December 2003. Eighteen of the 24 plates (75%) had been removed at the time of the study. In 72% restriction of the range of movement and pain due to plate impingement were the main causes for removal of the plate. Two of the plates (11%) were removed due to ‘mechanical failure’; the plate being levered off the bone or eroding the acromion. Mechanical failure of the plate was significantly associated with an older age group (P=0.01).

At the time of discharge from the clinic 57% had more than 50% of their shoulder movements, while 55.5% had minimal or no pain.

We suggest that Clavicle Hook Plates should be routinely removed as they cause impingement symptoms and they be used with caution (if at all) in the older age group given the tendency for the plate to lever off the bone.

Purpose: There are few reports in the literature detailing the arthroscopic treatment of multidirectional instability of the shoulder. The purpose of this study was to evaluate the results of arthroscopic methods in the treatment of athletes with symptomatic multidirectional instability of the shoulder.

Method: Forty patients (43 shoulders) with multidi-rectional instability of the shoulder were treated via arthrscopic means and were evaluated at a mean of 33.5 months post-operatively. The mean patient age was 19.1 years (range 14 to 39). There were 24 male patients and 16 female patients. Patients were evaluated with the ASES and WOSI scoring systems. Stability, strength, and range of motion were evaluated with patient-reported scales.

Results: The mean ASES score postoperatively was 91.4 out of 100. The mean WOSI post-operative percentage score was 91.1 out of 100. Ninety-one percent of patients had full or satisfactory range of motion, 98% had normal or slightly decreased strength, and 86% of patients were able to return to their sport with little or no limitation.

Conclusion: Arthroscopic methods can provide an effective treatment for symptomatic multidirectional instability in an athletic population.

Objectives: Total ankle replacement (TAR) is increasingly used for treatment of primary or posttraumatic arthritis of the ankle joint, if joint movement is intended to be preserved. Data on characteristics and treatment of ankle prosthetic joint infection (PJI) is limited and no validated therapeutic algorithm exist. Therefore, we analyzed all infections, which occurred in a cohort of implanted ankle prostheses during a 5-year-period.

Methods: Between 06/2004 and 12/2008, all patients with an implanted ankle prosthesis at our institution were retrospectively reviewed. All patients were operated by the same surgical team. Ankle PJI was defined as visible purulence, acute inflammation on histopathology, sinus tract, or microbial growth in periprosthetic tissue or sonication fluid of the removed prosthesis. The surgery on the infected ankle prosthesis and the follow-up were performed by the surgical team, who implanted the prosthesis. A specialized septic team consisting of an orthopaedic surgeon and infectious diseases consultant were included in the treatment.

Results: During the study period, 92 total ankle prostheses were implanted in 90 patients (mean age 61 years, range 28–80 years). 78 patients had posttraumatic arthritis, 11 rheumatoid arthritis and 3 other degenerative disorder. Ankle PJI occurred in 3 of 92 TAR (3.3%), occurring 1, 2 and 24 months after implantation; the causative organisms were Enterobacter cloacae, Streptococcus pyogenes and Staphylococcus epidermidis, respectively. The ankle prosthesis was removed in all infected patients, including debridement of the surrounding tissue was debrided and insertion of an antibiotic loaded spacer. Provisional arthrodesis was performed by external fixation in two patients and by plaster cast in one. A definitive ankle arthrodesis with a retrograde nail was performed 6 to 8 weeks after prosthesis removal. One patient needed a flap coverage. All 3 patients received intravenous antibiotic treatment for 2 weeks, followed by oral antibiotics for 4–6 weeks. At follow-up visit up to 18 months after start of treatment, all patients were without clinical or laboratory signs of infection.

Conclusions: The infection incidence after TAR was 3.3%, which is slightly higher than reported after hip (< 1%) or knee arthroplasty (< 2%). A two-step approach consisting of removal of the infected prosthesis, combined with local and systemic antibiotic treatment, followed by definitive ankle arthrodesis shows good results. Larger patient cohort and longer follow-up evaluation is needed to define the optimal treatment approach for ankle PJI.

Introduction: The ‘Two Week Wait’ (2ww) process has been in force since the year 2000, with the subsequent implementation of 32-day diagnosis and 62-day treatment ‘rules’ in 2005. The aims of this study were to compile a definitive diagnostic profile of 2ww referrals, establish whether a histological biopsy was required for diagnosis and consider the current 2ww impact on services in our centre.

Materials and Methods: Two hundred and nine patients were referred under 2ww to the North of England Bone and Soft Tissue Tumour service and prospectively recorded on a computerised multidisciplinary tumour database from 2006–8. The data was reviewed and verified using pathology, radiology reports and patient records.

Results: Malignancy was diagnosed in 41(20%) patients. This comprised 21 soft tissue sarcomas (10%), 11 primary bone tumours (5%), and 9 metastatic bone tumours (4%). 63 (30%) benign bone or soft tissue neoplasia and 80 (38%) non-neoplastic conditions were diagnosed. No mass lesion was identifiable in 25 patients (12%). A diagnostic or therapeutic biopsy was required in 108 (52%) patients.

Discussion and Conclusion: 15% of 2ww referrals to our centre have a primary bone or soft tissue sarcoma but over half of all 2ww patients require biopsy for diagnosis creating additional strains on resources under the 32- and 62-day rule. Emphasis is placed on obtaining a rapid diagnosis, to ease pressure on time to treatment, utilising a ‘one-stop clinic’ approach for biopsies of accessible tumours where applicable. The availability of timely radiological resources, facilitated by an MDT involving a designated coordinator (‘patient-tracker’), is key to ensure treatment is not delayed for any cancer patient regardless of referral route. Our centre is 100% compliant for waiting times for sarcoma according to the Department of Health 2008 data.

Methods: Records of 130 cases of bone or joint infection treated with teicoplanin, 10 mg/kg/day without loading dose alone or in combination therapy, at day hospital ward of Amedeo di Savoia Hospital, Turin, between 1995 and 2002 were reviewed.

Pathogens, whenever possible, were identified from blood, bone, tissue or exudate samples and antibiotic susceptibility was tested using the disk method.

Demographic details, type of infection, presence of prosthetic material, duration of treatment, concomitant and subsequent antimicrobial agents, serum creatinine, adverse events, outcome at the end of treatment, and length of follow-up were noted from patient records. Results: Eighty-eight patients (67.7%) were male and 42 (32.3%) female. Their ages ranged from 15 to 89 years, with a median of 50 years.

The most common infections were chronic osteomyelitis with or without foreign material [96 cases (73.9%)], with a median duration of 15 months (range 1–180 months): 30 with osteosynthetic material and 22 with prosthetic implants (15 patients who had received total hip replacements and 7 patients with total knee replacements). There were 44 diagnoses of chronic osteitis not associated with foreign material or prosthetic implants. Twenty-three were septic arthritis (17.6%), 11 (8.5%) spondylitis.

In 81 cases the pathogens identified from samples of blood, bone or exudate were staphylococci (61 of Staphylococcus aureus, 20 of Staphylococcus epidermidis). In 11 cases were isolated Gram-negative bacteria, such as Pseudomonas aeruginosa (6), Proteus mirabilis (3), Enterobacter cloacae (2). Where more than one species was isolated (1 case) a combination of a Enterococcus faecalis and Pseudomonas aeruginosa (a case of spondylitis) was identified.

The causative pathogen was not identified in 37 cases (28.5%). Teicoplanin was administered i.v. at a dosage of 10 mg/kg/day once a day, alone or in combination therapy with other antibiotics. Patients received teicoplanin i.v. alone in 5 cases and with 1–3 concurrent antibiotics (ceftriaxon in most cases) for a mean time of 4.5 months (R 2–12). The final assessment was that cure or improvement (clinical success) was achieved in 102 patients (78.5%); in 3 cases (2.3%) was recorded a clinical failure for persistence of infection signs but bacteriological eradication was achieved in all cases. During the follow-up, which varied from 1 to 48 months (median 8 months) twenty-one patients (16.1%) relapsed. Nine were patients with prosthetic implants. The other recurrences were recorded in cases of chronic osteomyelitis with foreign material. Four patients (3.1%) with prosthetic joint infection were given chronic suppression therapy. Eight patients showed adverse reactions, but discontinuation of teicoplanin treatment was not necessary. Conclusions: Teicoplanin has been shown to be effective as monotherapy or combination therapy for bone and joint infections.

Purpose: The purpose of this work was to evaluate the mid-term clinical and radiological outcome of a homogeneous and continuous series of third-generation total ankle prostheses (resurfacing, cylindric, noncemented, triple-compartment).

Material and methods: From March 1990 to June 1996, 26 patients aged 57 years (32–73) were treated with a New Jersey LCS (n=5) or Buechel-Pappas (n=21) prosthesis. Most of the patients (n=21) had a posttraumatic ankle. Preoperatively, mean ankle motion was 17°. The AOFAS score was used for the clinical assessment. The position of the prosthesis and its stability over time were assessed on the x-rays together with the insert, the bone-prosthesis interface, the bone structure and periprosthetic ossifications.

Results: Intra and postoperative complications were malleolar fracture (n=5), haematoma (n=1), late wound healing (n=1), insert instability (n=2), and medial malleolar conflict (n=1) requiring reoperation with preservation of the implant. At mean follow-up of seven years, two patients had died and one was lost to follow-up. Three had an arthrodesis: failed fixation at two years, secondary talar mobilisation at seven years, and secondary infection at eight years. For the other twenty patients: the AOFAS score was poor for two patients (including one with patent wear), fair in two, and good in 16. Mean joint motion at last follow-up was 24°. Radiographically, there were no significant changes in the position of the tibial and talar elements. Anchorage of the tibial element was fibrous in half of the patients and ossesous in the other half. A macro defect aspect was observed below the talar element in four patients. There were active periprosthetic ossifications in the majority of the patients.

Discussion: The insufficient ancillary for this prosthesis and its old concept explain the frequency of malleolar fractures and the level of the functional outcomes. Improved prostheses should be used. The stability of the results observed in this series of patients followed up to 12 years is an argument favouring indicating prosthesis insertion as an alternative to arthrodesis, particularly since revision of an arthrodesis is not particularly difficult, even with an iliac graft. The radiographic evidence of periprosthetic ossifications or bone resorption, particularly under the implant, emphasises the need for prolonged surveillance.

Standard therapy for soft-tissue sarcomas remains complete resection, irresectable tumours or tumours after resection with gross residual disease are a special challenge. For primary radiotherapy with median 60 Gy local control rates of 30–45% have been reported. We analysed retrospectively 11 cases of radiochemotherapy with single-agent Ifosfamide in patients with macroscopic soft-tissue sarcomas.

The patients were treated in irresectable high risk situations: T2-tumours (100%), G3 (73%), localisation at the trunk (82%). Radiation therapy was performed with median 60 Gy (50 to 72.6 Gy) in 1.8–2.0 Gy single fraction dose, once daily, five times a week. During the first and fifth week the concommittant chemotherapy with 1.0/1.5 gr/m2/d Ifosfamide on five days was added. Two patients received trimodal therapy with additional hyperthermia. The therapy was completed in 73% of the patients. Average local control time was 91 months, median disease-free-survival/overall-survival was 8/26 months. Five-year rates for local control/disease free survival/overall survival were 70%/34%/34%. Long-term tumor control could be achieved in three patients. The median disease free survival is dependant on the histological tumor grading (21 vs 8 months for G2 vs G3 tumors, no statistical significance due to small patient numbers). The limited prognosis is mainly caused by systemic treatment failure.

Concomitant radiochemotherapy with Ifosfamide in patients with macroscopic soft-tissue-sarcomas yields a good local control rate of 70% compared to previously published 30% in definitive radiotherapy with similar radiation doses. Additional simultaneous chemotherapy should be considered for irresectable soft tissue sarcomas or tumors after resection with gross residual disease, if the applicable radiation dose is limited due to close vicinity of organs at risk. A decrease of systemic failure with additional chemotherapy might be speculated.

Background: Retrograde ejaculation has been reported to range from 2% to 16% following anterior surgical approaches to lower lumbar spine, but the exact incidence is not known. It has been felt for sometime that transecting or extensive dissection of the hypogastric plexus about the lumbo sacral junction could interrupt the sympathetic control of urogenital system and interfere with sexual function.

Invasive tests such as urodynamic tests, anorectal manometry and post ejaculatory urine sample would precisely determine its incidence. As a first step we, along with Urogynaecologist devised and validated a questionnaire to determine the urogenital function post operatively.

Aims & Methods: To retrospectively determine the incidence of sympathetic dysfunction in anterior lumbar spine surgery. 46 of 60 patients (76% response) who had anterior lumbar spinal surgery answered a validated questionnaire with urinary and bowel function, International Index of Erectile Function (IIEF) for men and Female Sexual Function Index (FSFI).

Results: All the females post operatively had retained bowel function and there were no reported cases of sense of urgency, incontinence of stools or flatus. But only one patient reported urinary stress incontinence. There was no change of sexual function as concluded from FSFI score.

In males we had 3 cases of retrograde ejaculation which affected the sexual function (based on IIEF score), and were reported to be resolving slowly. There was no incidence of any urinary or bowel dysfunction postoperatively.

Conclusions: This retrospective study only showed the overall picture of the incidence of pelvic floor dysfunction following anterior spinal surgery. A prospective trial is underway to determine its incidence.

Purpose of the study: Treatment of comminutive fractures of the distal radius in elderly subjects remains a debated issue. Use of locked plates has given interesting results, particularly in the young subject. External fixation remains the simple osteosynthesis technique with the advantage of being minimally invasive and well adapted to the quality of bone in the elderly subject. The purpose of this work was to evaluate the mid-term results of a series of radiometacarpal joint bridgings of comminutive fractures of the distal radius.

Material and methods: From January 2003 to December 2007, 44 radiometacarpal fixations were assemblied and included in a retrospective radioclinical study. All of the fractures were comminutive (AO classification: C2 20.4%, C3 79.6%) in subjects aged over 60 years. Surgery consisted in a radiocarpal assembly alone (25%) or associated with another fixation (75%). The PRWE score was used for the functional assessment and the Sofcot 2000 symposium criteria for the radiographic analysis. Factors of poor prognosis were studied.

Results: Forty-four patients were reviewed with a mean follow-up of 28 months. Five patients were lost to follow-up. All patients had healed at mean 6.8 weeks. The functional outcome was good or very good in 45.4% of patients. Radiographically, anatomic restitution was achieved in 15.9% with a moderate to severe callus deformity in 84.1%. Fifteen complications were noted: reflex dystrophy (n=5), neuroma (n=2), material migration (n=6), disassembly with surgical revision (n=2) and superficial infection (n=2).

Discussion: Unlike observations in the young subject, there does not appear to be a consensus on the treatment of comminutive fractures of the distal radius in the elderly osteoporotic subject. External fixation has been used for many years for comminutive fractures. Our results nevertheless illustrate the limitations of this technique, both in terms of the functional outcome (54.6% insufficient results) and radiographic outcome (84.1% callus deformities). The only good results obtained with the external fixator occurred when the technique was associated with another fixation method. This suggests we should consider fixation of the wrist as a temporary osteosynthesis which should be replaced by another method (locked plating).

A combined posterior-anterior approach is usually proposed for the fixation of highly unstable spinal lesions. A monocortical anterior fixation seems to become more and more popular. In the period from 1993 to 1998, 43 patients with minimally anterior and middle column destruction of thoracolumbar spine were anteriorly instrumented. There were 23 tumors, 11 specific infections, 5 posttraumatic conditions with failed posterior instrumentation, 4 acute fractures. Anterior instrumentation (45Nm rod-screw rotation rigidity) were used in all cases. A four screws principle with two non connected rods were bicortically applied to correct the deformity and to fix the corpectomy gap. No postoperative bracing was necessary. There was one pseudarthrosis 2yrs post op. due to poor anterior fusion in a posttraumatic case. In one case instrumentation failure occurred due to widespreading of the prostatic tumor. The study revealed no complications due to bicortical screw fixation in thora-columbar region. It is suggested that combined anterior and posterior procedure is only exceptionally necessary.

Introduction. The aim of this study was to retrospectively evaluate the efficacy of the SpineCor bracing treatment in all forms of scoliosis, between 2000–2006.

Methods. Over the past 6 years 56 skeletally immature and 1 skeletally mature patients with progressive scoliosis have been treated with the Spine-Cor bracing system. They were divided into the following groups; infantile 3; juvenile 19; adolescent 29; adult 1; “other” 5.

Results. 20 were deemed to have achieved a correc-tion, 24 stabilised 3 worsened and the progression of 4 patients was not recorded. To date 11 patients have gone on to surgery.

Discussion. Various bracing systems utilised in the past have shown what appeared to be a lasting degree of protection for scoliosis but subsequent long term follow ups have demonstrated progression of curves. The newer SpineCor system may offer a good short term outcome.

Conclusion. Early diagnosis and rapid treatment at a young skeletal age may offer an alternative to surgery with this relatively new bracing system. A further prospective study continues at S.C.H. and will be ready to present in 2011. Far longer term follow up will be required to validate apparent successes in the short term.

Purpose of the study: Special care is warranted only for severe forms of Legg-Perthes-Calvé disease (LPCd) (Catterall 4, Herring B and C, Salter B, involvement > 50%). Should we propose specific treatment or simply monitor the inevitable disease course?

Material and method: Among a series of 485 hips with LPCd, 148 (30.5%) with massive involvement were identified. Ninety-six (64.9%)severe forms were analyzed at the end of growth. Magnetic resonance imaging, scintigraphy and arteriography were used to better assess the femoral head and identify hips at risk. These hips were treated surgically: Salter osteotomy (SA), triple pelvis osteotomy (TO), or varus osteotomy (VA). Three groups of infants were identified according to age at diagnosis of LPCd: less than 6 years, 6–9 years, more than 9 years. Outcome was considered good (Stulberg 1 and 2, Mose good), fair (Stulberg 3, Mose fair), or poor (Stulberg 4 and 5, Mose poor).

Results: There were 54 hips (56.3%) in the less than 6 years group, 26 (27.1%) in the 6–9 years groups, and 16 (16.6%) in the greater than 9 years group. Outcome was good for 45 hips (46.9%), fair for 22 (22.9%) and poor for 29 (31.2%) hips and was independent of age at onset of treatment. In the less than 6 years group, 54 hips (56.3%) were Catterall 4, Herring B or C, Salter B. Among the 24 Catterall 4 hips (44.4%) treated orthopedically, outcome was good for 15 (62.5%), fair for 7 (29.2%) and poor for 2 (8.3%). Among the 30 Cartell 4 hips treated surgically, outcome was good for 16 (53.3%), fair for 9 (30%) and poor for 5 (16.7%). In the 6–9 year group, 26 hips (27.1%) were Catterall 4, Herring B or C, Salter B. Among the 10 Catteral 4 hips treated orthopedically (38.5%), outcome was good for 3 (30%), fair for 2 (20%) and poor for 5 (50%). For the 16 Catterall 4 hips treated surgically, outcome was good for 8 (50%), fair for 2 (12.5%) and poor for 6 (37.5%). In the greater than 9 years group, there were 16 (16.6%) Catterall 4, Herring B or C, Salter B hips. Among the 10 Catterall 4 hips treated orthopedically, outcome was good for 1 (10%), fair for 2 (20%) and poor for 7 (70%). Among the 6 Catterall hips treated surgically, outcome was good for 2 (33.3%), fair for 0 and poor for 4 (66.7%).

Conclusion: Good outcome decreases with age. Surgery increases the rate of good outcome in all age groups, but before the age of six years, there is no significant difference between orthopedic and surgical treatment. Before six years, spherical heads (Stulberg 1 and 2) were achieved in six out of ten hips in the 6–9 year group and in only two of ten in the group aged over 9 years.

There is a high risk of the development of avascular necrosis of the femoral head and nonunion after the treatment of displaced subcapital fractures of the femoral neck in patients aged < 50 years. We retrospectively analysed the results following fixation with two cannulated compression screws and a vascularised iliac bone graft. We treated 18 women and 16 men with a mean age of 38.5 years (20 to 50) whose treatment included the use of an iliac bone graft based on the ascending branch of lateral femoral circumflex artery. There were 20 Garden grade III and 14 grade IV fractures. Clinical and radiological outcomes were evaluated. The mean follow-up was 5.4 years (2 to 10). In 30 hips (88%) union was achieved at a mean of 4.4 months (4 to 6). Nonunion occurred in four hips (12%) and these patients had a mean age of 46.5 years (42 to 50) and underwent revision to a hip replacement six months after operation. The time to union was dependent on age with younger patients achieving earlier union (p < 0.001). According to the Harris hip score which was available for 27 of the 30 hips with satisfactory union, excellent results were obtained in 15 (score ≥ 90 points), fair in ten (score 80 to 90 points), and poor in two hips (≤ 80 points). One patient aged 48 years developed avascular necrosis of femoral head six years after operation and underwent total hip replacement.

The management of displaced subcapital fractures of the femoral neck, in patients aged <  50 years, with two cannulated compression screws and an iliac bone graft based on the ascending branch of lateral femoral circumflex artery, gives satisfactory results with a low rate of complication including avascular necrosis and nonunion.

Cite this article: Bone Joint J 2014;96-B:1024–8.

Aim

Synovial sarcoma (SS) is a malignant soft tissue sarcoma with a poor prognosis because of late local recurrence and distant metastases. To our knowledge, no studies have minimum follow-up of 10 years that evaluate long-term outcomes for survivors.

Aims: The optimal treatment of Type II odontoid fractures remains controversial. Our retrospective multicentric study of 114 odontoid process fractures documents experience with management of these fractures and discuss a new classification subtype II T and its surgical treatment. Methods: Fractures were defined using plain radiographs and CT reconstructions as per the Anderson- D’Alonzo classification. We have surgically treated 114 consecutive patients suffering from C2 odontoid fracture. 104 fractures were classified as Type II and 10 as Type III. Two cases of atypical, horizontal, mid-shaft odontoid process fractures were reported. In 55% an anterior two-screw fixation technique was chosen, remaining 45% underwent single-screw fixation. Results: One year follow-up data were available in 86.8% of cases and no major complications were found. Fusion rate calculated 6 months following surgery was 93%. We encountered cases, where the fracture line passes transversally through the middle of the shaft of odontoid process, below the level of transverse atlantal ligament, and we suggest to classify these cases as Type II T fractures. Also we analysed series of 75 surgically treated C1-2 instabilities and out of 11 pseudoarthrosis of the odontoid process 7 unrecognised Type II T fractures were found. Conclusions: Reported atypical fractures, newly classified as Type II T, are highly unstable (especially in rotations). In the authors’ opinion, two- screw technique should be the treatment of choice when internal fixation indicated.

Purpose of the study: Pelvic fractures disrupting the pelvic girdle often create a serious challenge for reduction and fixation. Type C fractures of the Tile classification provoke vertical instability. Percutaneous screw fixation under fluoroscopic control in patients positioned in dorsal decubitus enables an extension of early indications for fixation to patients with abdominal or thoracic injuries. The reduction is obtained by progressive transcondylar traction on an orthopedic table. The purpose of this study was to assess functional mid-term outcome and to analyze causes of failure.

Material and methods: From 1995 through 2003, we used the percutaneous sacroiliac screw fixation method for type C fractures in 25 patients; clinical assessment at 45 months mean follow-up was available for 22 patients. Six patients presented a bilateral lesion (C2), seven a vertical sacral fracture (C1-3), and nine sacroiliac disjunction (C1-2). One screw was inserted for ten patients, two screws for twelve. Complementary anterior osteosynthesis was performed for eight patients.

Results: The functional outcome was assessed with the Mageed score. The mean score was 801%. All patients presente satisfactory postoperative reduction (less than 10 mm residual vertical displacement). Early displacement was noted one day 10 in one patient who underwent a revision procedure. There were two late secondary displacements (one with mobilization and one with material fracture) which heal in a misaligned position. There were no iatrogenic complications (neurologic, vascular, infectious) and no cases of nonunion.

Discussion: The long-term functional results were directly related to the quality of the reduction, as previously demonstrated by Matta. In our series, the quality of the postoperative reduction was significantly correlated with time from trauma to surgery. This delay must be as short as possible (less than five days for Routt). The main complication was secondary displacement which was observed in this study among cases with a single posterior screw.

Conclusion: Percutaneous sacroiliac screw fixation provides good functional results and appears to be a safe technique if the initial reduction is satisfactory. Two posterior screws are needed to avoid secondary displacement.

Poor results increase in older patients. After Orthopaedic treatment 60% of hips in children with LPC Disease appearing before the age of 6 find again its sphericity (Stulberg 1 or 2). About 30 % of hips in children with LCP Disease appearing between 6 and 9 years of age became “normal” (Stulberg 1 or 2) at the end of growth/Only 1 hip out of 10, in the oldest group of children (over 9 years), became spherical at the end of growth. Surgery increases the percentage of good results in all groups of patients.

Aim: The aim is to correlate intra-operative findings such as epidural fibrosis (EF), size and type of disc fragment, lateral recess stenosis and dural tear with postoperative residual radiculopathy (RR) and residual low back pain (RLBP).

Material and Methods: 246 revision discectomies performed between January 1994 and June 2004 were considered, of which adequate records were available for 215 (201 ipsilateral and 14 contralateral). Of 201 LIRDs, 85 were at L5S1, 101 at L45, 10 at L5S1+L45, 3 at L34 and 2 at L23 level. Patients who had had fusion or instrumentation in addition to LIRD were excluded. For 201 LIRDs average follow-up was 18.5 months (range −1 to 96 months) and 100 LIRDs had a minimum of 12 months’ follow-up.

Results: Of the 179 first-time LIRDs, 65 (36.3%) had significant RR, 73 (40.8%) significant RLBP, 3 (1.7%) cauda equina syndrome, 2 (1.1%) infective discitis, and 1 (0.6%) foot-drop. Of the 21 second-time LIRDs, 15 (71.4%) had significant RR, 17 (81%) significant RLBP, 2 (9.5%) infective discitis and 1 (4.8%) cauda equina syndrome. EF was classified as abundant, moderate and scant. Incidence of RR and RLBP was proportional to amount of EF and size of hypertrophic scarred ‘disc’ bulge, but it correlated poorly with size of ‘soft’ disc prolapse. Lateral recess decompression in addition to LIRD did not significantly alter the incidence of RR and RLBP.

25 (12.4%) patients who had dural tear had worse results.

Conclusions: Large proportion of LIRDs result in significant residual symptoms. Second-time LIRDs have higher complication rates and even poorer outcomes.

Aims

The principles of evidence-based medicine (EBM) are the foundation of modern medical practice. Surgeons are familiar with the commonly used statistical techniques to test hypotheses, summarize findings, and provide answers within a specified range of probability. Based on this knowledge, they are able to critically evaluate research before deciding whether or not to adopt the findings into practice. Recently, there has been an increased use of artificial intelligence (AI) to analyze information and derive findings in orthopaedic research. These techniques use a set of statistical tools that are increasingly complex and may be unfamiliar to the orthopaedic surgeon. It is unclear if this shift towards less familiar techniques is widely accepted in the orthopaedic community. This study aimed to provide an exploration of understanding and acceptance of AI use in research among orthopaedic surgeons.

Introduction: Direct exchange of total hip arthroplasty as a single stage revision procedure for aseptic loosening represents a significant proportion of the revision surgeon’s case load, accounting for 38% of cases in the Sheffield Lower Limb Arthroplasty Unit. In our unit current practice is to obtain preoperative negative hip aspirates and normal inflammatory markers and take 5 intraoperative deep tissue samples for microbiological culture. The aim of this retrospective, observational study was to evaluate the necessity of this technique.

Method: 100 consecutive direct exchanges to total hip replacements for aseptic loosening performed in our unit between 03/10/2005 and 31/07/2007 were identified using the arthroplasty database and their case notes reviewed. The microbiological results were evaluated by a microbiology consultant and the notes were examined. A minimum of 1 year follow-up was obtained in all patients.

Results: 42 patients were found to have one or more positive sample. Of these 37 were deemed by the microbiologist to be contaminants and 5 to have a significant growth. Of the 5 with significant growth, 2 patients were treated with systemic antibiotics as a result of microbial tissue sample growth. At the latest follow up appointment (range 22–33 months) these 5 patients were all clinically not infected.

Conclusion: The practice of obtaining routine deep tissue samples is essential for revision surgery performed for aseptic loosening. 5% of patients in our series had a significant bacterial growth despite being presumed to be aseptic which would otherwise not have been detected. The support of a microbiologist with dedicated arthroplasty interest is vital in determining the relevance of sample results.

Over the last 10 years atypical femoral fractures (AFFs) have become recognised as a complication of standard-dose bisphosphonate use. In 2014 the American Society for Bone and Mineral Research published updated diagnostic criteria for AFF. We undertook a 5-year retrospective analysis of the trauma admission database at a major trauma centre to establish the incidence of this problem in our patient population. Initial screening was performed using keyword-matching methodology to produce a shortlist of patients with low-energy femoral fractures. These patients’ case notes, radiographs, and electronic discharge summaries were reviewed to discriminate AFF from typical femoral fractures. Initial filtering identified a total of 112 low energy femoral fractures. Of these, 12 were confirmed as AFFs. 58% (7/12) of the AFF group were on bisphosphonates compared to 15% (15/100) of the typical femoral fracture group. This finding was statistically significant (p = 0.0004). These data show that there is a link between bisphosphonate use and AFF. However, a causal relationship cannot be inferred. The incidence of AFF in our study is broadly in line with the published data