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The Bone & Joint Journal
Vol. 99-B, Issue 10 | Pages 1286 - 1289
1 Oct 2017
Rajpura A Board TN Siney PD Wynn Jones H Williams S Dabbs L Wroblewski BM

Aims

Our aim in this study was to describe a continuing review of 11 total hip arthroplasties using 22.225 mm Alumina ceramic femoral heads on a Charnley flanged femoral component, articulating against a silane crosslinked polyethylene.

Patients and Methods

Nine patients (11 THAs) were reviewed at a mean of 27.5 years (26 to 28) post-operatively. Outcome was assessed using the d’Aubigne and Postel, and Charnley scores and penetration was recorded on radiographs. In addition, the oxidation of a 29-year-old shelf-aged acetabular component was analysed.


Bone & Joint Research
Vol. 1, Issue 3 | Pages 25 - 30
1 Mar 2012
Wroblewski BM Siney PD Fleming PA

Objectives

Metal-on-metal (MoM) hip resurfacing was introduced into clinical practice because it was perceived to be a better alternative to conventional total hip replacement for young and active patients. However, an increasing number of reports of complications have arisen focusing on design and orientation of the components, the generation of metallic wear particles and serum levels of metallic ions. The procedure introduced a combination of two elements: large-dimension components and hard abrasive particles of metal wear. The objective of our study was to investigate the theory that microseparation of the articular surfaces draws in a high volume of bursal fluid and its contents into the articulation, and at relocation under load would generate high pressures of fluid ejection, resulting in an abrasive water jet.

Methods

This theoretical concept using MoM resurfacing components (head diameter 55 mm) was modelled mathematically and confirmed experimentally using a material-testing machine that pushed the head into the cup at a rate of 1000 mm/min until fully engaged.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 547 - 547
1 Nov 2011
Purbach B Wroblewski BM Siney PD Fleming PA Kay PR
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Introduction:. The C-Stem in its design as a triple tapered stem, is the logical development of the original Charnley flat-back polished stem. The concept, design and the surgical technique cater for a limited slip of the stem within the cement mantle transferring the load more proximally.

Method: Five thousand two hundred and thirty three primary procedures using a C-stem have been carried out since 1993. We reviewed all 621 cases that had their total hip arthroplasty before 1998.

Results:. Sixty nine patients (70 hips) had died and 106 hips had not reached a ten-year clinical and radiological follow-up and had not been revised. In 22 hips, the stem had been changed before the 10 year follow-up, with infection, dislocation and loosening of the cup being the reasons for revision. None of the stems were loose.

The remaining 423 hips had a mean follow-up of 11 years (range 10 – 15 years). There were 216 women and 173 men, and 34 patients had bilateral LFAs. The patients’ mean age at surgery was 53 years (range 16 – 83 years). Thirty eight hips had been revised at the time of review. The reasons for revision were infection in 5: dislocation in 2: loose cup in 28: wear in 2 and 1 for meralgia paresthetica where the stem was found to be well fixed. In 1 case which had not been revised there was radiological loosening of the stem in a patient with Gaucher’s disease.

Discussion: With only 1 stem radiologically loose and no revisions for stem loosening the clinical results are very encouraging and they support the concept of the Charnley cemented low friction arthroplasty, but place a demand on the understanding of the technique and its execution at surgery.


The Journal of Bone & Joint Surgery British Volume
Vol. 92-B, Issue 4 | Pages 486 - 488
1 Apr 2010
Wroblewski BM Purbach B Siney PD Fleming PA

Increasing follow-up identifies the outcome in younger patients who have undergone total hip replacement (THR) and reveals the true potential for survival of the prosthesis. We identified 28 patients (39 THRs) who had undergone cemented Charnley low friction arthroplasty between 1969 and 2001. Their mean age at operation was 17.9 years (12 to 19) and the maximum follow-up was 34 years. Two patients (4 THRs) were lost to follow-up, 13 (16 THRs) were revised at a mean period of 19.1 years (8 to 34) and 13 (19 THRs) continue to attend regular follow-up at a mean of 12.6 years (2.3 to 29). In this surviving group one acetabular component was radiologically loose and all femoral components were secure. In all the patients the diameter of the femoral head was 22.225 mm with Charnley femoral components used in 29 hips and C-stem femoral components in ten. In young patients who require THR the acetabular bone stock is generally a limiting factor for the size of the component. Excellent long-term results can be obtained with a cemented polyethylene acetabular component and a femoral head of small diameter.


The Journal of Bone & Joint Surgery British Volume
Vol. 91-B, Issue 7 | Pages 855 - 858
1 Jul 2009
Wroblewski BM Siney PD Fleming PA

The design of the Charnley total hip replacement follows the principle of low frictional torque. It is based on the largest possible difference between the radius of the femoral head and that of the outer aspect of the acetabular component. The aim is to protect the bone-cement interface by movement taking place at the smaller radius, the articulation. This is achieved in clinical practice by a 22.225 mm diameter head articulating with a 40 mm or 43 mm diameter acetabular component of ultra-high molecular weight polyethylene.

We compared the incidence of aseptic loosening of acetabular components with an outer diameter of 40 mm and 43 mm at comparable depths of penetration with a mean follow-up of 17 years (1 to 40).

In cases with no measurable wear none of the acetabular components were loose. With increasing acetabular penetration there was an increased incidence of aseptic loosening which reflected the difference in the external radii, with 1.5% at 1 mm, 8.8% at 2 mm, 9.7% at 3 mm and 9.6% at 4 mm of penetration in favour of the larger 43 mm acetabular component.

Our findings support the Charnley principle of low frictional torque. The level of the benefit is in keeping with the predicted values.


The Journal of Bone & Joint Surgery British Volume
Vol. 91-B, Issue 4 | Pages 447 - 450
1 Apr 2009
Wroblewski BM Siney PD Fleming PA

Of the 11 054 Charnley low-frictional torque arthroplasties carried out at our hospital between 1962 and 1977, 110 (94 patients) had a minimum follow-up of 30 years with a mean of 32.3 years (30.0 to 40.5). The mean age of the patients at operation was 43.3 years (17.0 to 65.0) and 75.7 years (51.0 to 97.0) at follow-up. Overall, 90% of hips (99) were free from pain and activity was reported as normal in 58% of the patients.

A total of 13 hips (11.8%) were revised at a mean follow-up of 32.3 years (30.0 to 39.5), with wear and loosening of the acetabular component as the main indications.

The clinical results did not reflect the mechanical state of the implant. Follow-up with sequential radiographs of good quality is essential. Revision for radiological changes alone must be accepted if gross loss of bone stock is to be avoided.

Improvements in the design, materials and operative technique, based on the long-term outcome, are highlighted.


The Journal of Bone & Joint Surgery British Volume
Vol. 89-B, Issue 8 | Pages 1015 - 1018
1 Aug 2007
Wroblewski BM Siney PD Fleming PA

We studied survival to 38 years after Charnley low-friction arthroplasty of the hip. We used revision as an end-point, while adopting a policy of regular follow-up and early revision for radiological changes alone if indicated.

Between November 1962 and June 2005, 22 066 primary low-friction arthroplasties (17 409 patients) had been performed at Wrightington Hospital by more than 330 surgeons. By June 2006, 1001 (4.5%) hips had been revised and 1490 patients (2662 hips, 12%) had died. At 31 years, where a minimum of 40 hips were still attending follow-up, survival with revision for infection as an endpoint was 95%, for dislocation 98%, for a fractured stem 88.6%, for a loose stem 72.5% and for a loose acetabular component 53.7%. Wear and loosening of the ultra-high-molecular-weight polyethylene acetabular component were the main long-term problems.

We conclude that regular follow-up after hip replacement is essential and that all operative findings should be recorded at revision.


The Journal of Bone & Joint Surgery British Volume
Vol. 88-B, Issue 2 | Pages 184 - 187
1 Feb 2006
Wroblewski BM Siney PD Fleming PA

We reviewed 1039 revision total hip replacements where an angle-bore acetabular component was used. After a mean follow-up of nine years (0 to 20.6), the incidence of revision for dislocation was 2.1% (22 revisions), a success rate of 97.9%. In 974 revisions, where the indication was other than dislocation, the success rate was 98.5%. Of the 65 revisions for dislocation, 58 (89.2%) were successful after the first revision and a further five after the second revision, an overall success of 96.9%. Two patients elected to have their implants removed. Dislocation after revision of failed total hip replacement is a complex issue. There is often no single cause and no simple solution. The angle-bore acetabular component, in combination with a 22.225-mm diameter femoral head, offers a high level of success.


The Journal of Bone & Joint Surgery British Volume
Vol. 87-B, Issue 9 | Pages 1220 - 1221
1 Sep 2005
Wroblewski BM Siney PD Fleming PA

We report the results of our continued review of 11 total hip arthroplasties using 22.225 mm alumina ceramic femoral heads on a Charnley flanged stem, articulating with chemically cross-linked polyethylene. There was an initial bedding-in of up to 0.41 mm at the articular surface in the first two years. This had not progressed further, at a minimum follow-up of 15 years. Radiographically no femoral or acetabular component showed loosening or osteolysis.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_I | Pages 43 - 43
1 Mar 2005
Nagai H Nagai R Siney PD Kay PR Wroblewski BM
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Background: Dislocation after total hip replacement (THR) is a significant concern with the increased number of THR carried out all over the world, although there has been a substantial lack of information regarding revision THR for instability in literature.

Purpose: The purpose of this study was to evaluate the effectiveness of operative treatment for recurrent dislocation after THR.

Material and methods: One hundred and eleven cases were treated operatively for recurrent dislocation after THR by a senior author (BMW). Group A; 104 cases were operated with change of either or both of components, a socket and a stem. Twenty-two mm head was used in 90 cases (A-1), 32 mm head in twelve (A-2), and 36 mm head in two (A-3). Group B; only modular head was changed in one case. Group C; augmentation device was applied on a cup in six cases. The average follow-up period was 6.2 years (range, 1 to 21 years).

Results: Group A-1; twelve cases (13%) required further operations for instability (N=90). Group A-2; one case (8.3%) was converted to Girdle-Stone for recurrent dislocation (N=12). Group A-3; one of them was revised for periprosthetic fracture (N=2). Group B; the case survived at the follow-up of 3.3 years (N=1). Group C; two cases (33%) were revised for dislocation (N=6).

Conclusion: We reported the largest series of revision THR for recurrent dislocation by a single surgeon with a considerable length of follow-up periods. Revision THR with change of components was an effective treatment for recurrent dislocation after THR.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_I | Pages 70 - 70
1 Jan 2004
Wroblewski BM Siney PD Fleming PA
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Since wear and loosening of the ultra high molecular weight polyethylene is the one factor limiting the life of the arthroplasty we set out to identify factors associated with either low wear 0.02 mm/year or less, or high wear 0.2 mm/year or more.

In a group of 1092 patients, 1434 Charnley low-friction arthroplasties 190 (13.2%) showed low wear while 149 (10.4%) showed high wear. We used Chi square test to assess the significance.

The characteristics of the low wear group were: female gender (p=0.042) Rheumatoid arthritis (p= 0.014), Charnley category “C” patients (p=0.03) and varus position of the stem (p=0.003) The use of acetabular cement pressurization (p=0.07) and medialization of the cup (p=0.07) approached significance.

In the high wear group there was a predominance of males (p=0.042) with primary arthritis (p=0.006) as the underlying hip pathology, and the stem in valgus position (p=0.023). Rim position of the cup was approaching significance (p=0.07). There was no statistical significance between the two groups for revision for aseptic stem loosening or stem fracture (p= 0.49). There was a highly significant difference (p< 0.0001) between the two groups for revision for wear and aseptic cup loosening: 5.3% against 40%.

Changes in the cup geometry are sufficient to explain the increasing incidence with depth of cup penetration. There is much to be gained from the use of low wearing ceramic – ultra high molecular weight combination. Tissue reaction to the plastic particles cannot be the cause of stem loosening.


The Journal of Bone & Joint Surgery British Volume
Vol. 85-B, Issue 3 | Pages 376 - 379
1 Apr 2003
Wroblewski BM Siney PD Fleming PA

We have prospectively studied the wear of enhanced ultra-high molecular-weight polyethylene (Hylamer) in combination with a zirconia femoral head of 22.225 mm diameter on a cemented, triple-tapered, collarless, polished stem, the C Stem.

The 71 patients who underwent total hip arthroplasty had a mean follow-up of six years (3 to 8). No patient died or was lost to follow-up. The clinical results were excellent with 96% of patients satisfied. There were no revisions. Two cups were considered to be loose radiologically. One was avulsed from the cement in a skiing accident, with a periprosthetic fracture of the femur, but has remained stable for more than seven years. One femur shows radiological appearances which are compatible with a healing infection. One femoral component is at risk of loosening. The mean rate of penetration of the cup was 0.22 mm/year (0.06 to 0.55).

Our results appear to be within the guidelines set by the National Institute of Clinical Excellence. We have discontinued the use of Hylamer despite excellent clinical results and no revisions to date because the high initial rates of penetration did not settle to the expected low levels within the anticipated time.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_I | Pages 20 - 20
1 Jan 2003
Wroblewski B Siney PD Fleming PA
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Ultra high molecular weight polyethylene (UHMWPE) was introduced into clinical practice by Charnley in November 1962 and has remained the standard material for the hip and other total joint arthroplasties.

Wear of the UHMWPE cup, although studied from the beginning, did not appear to be a clinical problem although Charnley suspected that this would be so in the long term.

A review of the outcome of the Charnley low-friction arthroplasty in patients under the age of 40 years at the time of the operation has shown that the incidence of cup migration was exponentially related to the depth of cup penetration. A prospective study using 22.225 mm alumina ceramic (Al 20 3 ) head articulating with cross linked polyethylene was set up with the initial penetration of 0.2 – 0.4 mm in about 2.5 years with no further penetration. The clinical results mirrored closely the experimental results obtained with the identical set of materials and design. The clinical results have now reached 14 year follow-up and the initial total penetration of 0.2 – 0.4mm has remained unchanged.

Review of long term results of the Charnley LFA has shown a mean penetration rate of 0.1 mm/year (0.02 – 0.6). With a mean penetration rate of 0.1 mm/year, the revision rate for cup wear and loosening in patients under the age of 50 at the time of the LFA, and with a follow-up to 32 years, is in the region of 10%. If the penetration rate remained at 0.02 mm/year or less then no cups have been revised for aseptic loosening. Ceramic / UHMWPE articulation is the next stage of evolution of the Charnley LFA. A prospective study using zirconia 22.225 mm head is approaching 7 year follow-up in over 1000 cases.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_I | Pages 22 - 22
1 Jan 2003
Wroblewski B Siney PD Fleming PA
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A prospective study of Charnley low friction arthroplasty in patients under the age of 51 at the time of surgery.

1092 patients, 668 women and 424 men, mean age 41 years (12–51) at the time of surgery had 1434 Charnley low-friction arthroplasties carried out between November 1962 and December 1990. At mean follow-up 14.2 years (1 – 32), 742 patients (973 hips) are still attending and patients’ satisfaction with the outcome is 96.2%. Survivorship was 95.24% at 10 years and 58.67% at 27 years.

Patients who had had previous hip surgery had revision rate 24.8% compared with 14.1%. Patients with rheumatoid arthritis had fewer revisions than those with developmental hip dysplasia or primary osteoarthritis. Large 43 mm diameter cup gave lower revisions for aseptic cup loosening as compared with 40mm cup. Presence and preservation of subchondral plate, rim support compared to medialization of the cup, use of acetabular cement pressurizer and the reduced diameter neck (10mm) all made a contribution to reducing the incidence of revisions for aseptic cup loosening. Closing the medullary canal with bone block reduced the incidence of aseptic stem loosening. Use of the brace reamers did not affect the outcome and there appears to have been no advantage with the flanged stem.

The long-term problem was the increasing incidence of revisions for aseptic cup loosening. This was exponentially related to the depth of cup penetration by the head of the femoral component.

The long term clinical results of the Charnley LFA remain excellent even in young patients. Rim support of the cup, preservation of the subchondral bone of the acetabulum, cup flange and pressurising of the acetabular cement all make a significant contribution. Distal closure of the medullary canal and central position of the stem are of benefit, but reaming the medullary canal to cortex must be avoided. The long-term problem has been highlighted again as: wear and cup loosening.


The Journal of Bone & Joint Surgery British Volume
Vol. 84-B, Issue 4 | Pages 540 - 543
1 May 2002
Wroblewski BM Siney PD Fleming PA

Between November 1962 and December1990 a group of 1092 patients, 668 women and 424 men, under the age of 51 years at the time of surgery, underwent 1434 primary Charnley low-frictional torque arthroplasties and are being followed up indefinitely. Their mean age at operation was 41 years (12 to 51). At the latest review in June 2001 the mean follow-up had been for 15 years 1 month. Of the 1092 patients 54 (66 hips) could not be traced, 124 (169 hips) were known to have died and 220 (248 hips) had had a revision procedure. At a mean follow-up of 17 years and 5 months, 759 patients (951 hips) are still attending. In this group satisfaction with the outcome is 96.2%.

The incidence of deep infection for the whole group was 1.67%. It was more common in patients who had had previous surgery (hemi- and total hip arthroplasties excluded), 2.2% compared with 1.5% in those who had not had previous surgery, but this difference was not statistically significant (p = 0.4). There were fewer cases of deep infection if gentamicin-containing cement was used, 0.9% compared with 1.9% in those with plain acrylic cement, but this was not also statistically significant (p = 0.4). There was a significantly higher rate of revision in patients who had had previous hip surgery, 24.8% compared with 14.1% in those who had not had previous surgery (p < 0.001).

At the latest review, 1.95% are known to have had at least one dislocation and 0.4% have had a revision for dislocation. The indication for revision was aseptic loosening of the cup (11.7%), aseptic loosening of the stem (4.9%), a fractured stem (1.7%), deep infection (1.5%) and dislocation (0.4%).

With revision for any indication as the endpoint the survivorship was 93.7% (92.3 to 95.0) at ten years, 84.7% (82.4 to 87.1) at 15 years, 74.3% (70.5 to 78.0) at 20 years and 55.3% (45.5 to 65.0) at 27 years, when 55 hips remained ‘at risk’.


The Journal of Bone & Joint Surgery British Volume
Vol. 82-B, Issue 6 | Pages 842 - 845
1 Aug 2000
Wroblewski BM Siney PD Fleming PA Bobak P

The calcar femorale is a vertical plate of bone lying deep to the lesser trochanter and is formed as a result of traction of the iliopsoas which separates the femoral cortex into two distinct layers, the calcar femorale and the medial femoral cortex. They fuse together proximally to form the medial femoral neck. A stem placed centrally will abut against the calcar femorale with little or no space for cement. Clearing of the calcar will offer space for a cement layer, which will support the stem proximally on the posterior aspect. We compared two consecutive groups of Charnley low-friction arthroplasties, with and without clearing of the calcar.

In 330 patients who had an arthroplasty without clearing the calcar, there were ten revisions for aseptic loosening of the stem and six other stems were considered ‘definitely loose’, giving a rate of failure of 4.8%. In 111 patients in whom the calcar was cleared there was only one revision for aseptic loosening and no stems were classed as ‘definitely loose’, giving a rate of failure of 0.9%.

Survivorship analysis has again shown the need for long-term follow-up; the differences became clear after ten years but because of the relatively small numbers, statistical analysis is not yet applicable.

We now clear the calcar femorale routinely and advocate optimal access to the medullary canal and insertion of the stem in the area of the piriform fossa.


The Journal of Bone & Joint Surgery British Volume
Vol. 82-B, Issue 5 | Pages 684 - 688
1 Jul 2000
Crawford SA Siney PD Wroblewski BM

We have designed a modular cemented femoral component for revision of failed total hip arthroplasty in which deficiency of the proximal femur is such as to require a variable extrafemoral portion of the stem. We present the results of the first 74 operations in 72 patients; 56 of the patients had grade-3 or grade-4 femoral deficiency as defined by Gustilo and Pasternak and 24 had fractures of the proximal femur, of which 22 were periprosthetic. There was or had been infection in 19 hips.

At a mean follow-up of 5 years 9 months (1 to 12 years) nine stems were radiologically loose of which three had been revised. There were no failures in 45 cases in which there was fixation of the distal stem of 10 cm or more. Dislocation occurred in nine patients and there were four cases of infection in the 19 which were, or had been, infected previously. There were no neurovascular complications and no intraoperative femoral fractures.

The femoral bone stock improved radiologically in 45 hips of which 29 showed considerable reformation of the proximal femur; 27 remained unchanged and two showed increasing osteoporosis.


The Journal of Bone & Joint Surgery British Volume
Vol. 82-B, Issue 4 | Pages 508 - 511
1 May 2000
Bobak P Wroblewski BM Siney PD Fleming PA Hall R

Between 1983 and 1988 we carried out 45 Charnley low-friction arthroplasties with autografts from the femoral head in 41 patients for developmental dysplasia of the hip.

The preoperative radiographs were assessed for the severity of DDH according to the classifications of Crowe et al, Hartofilakidis et al and Sharp. The postoperative and follow-up radiographs were analysed for coverage of the socket by the graft, for loosening and for the outcome of the fixation of the bone graft. Two patients died (two hips) at four and seven years after THR from causes unrelated to the surgery and were excluded from the final radiological analysis. The mean age of the patients at the time of operation was 46 years 3 months. The autograft of the femoral head covered a mean 26% (16 to 35) of the acetabular component. All the grafts united. Some degree of resorption of the bone graft occurred in 27 patients, and always involved the lateral part of the graft, which was beyond the margin of the socket. After a mean follow-up of 11 years there had been no revisions and 38 patients had no pain or only slight discomfort. One socket migrated and four others were fully demarcated.

Our findings indicate that the Charnley LFA with an autograft of the femoral head for DDH remains successful at a follow-up of 15 years.


The Journal of Bone & Joint Surgery British Volume
Vol. 81-B, Issue 3 | Pages 427 - 430
1 May 1999
Wroblewski BM Fleming PA Siney PD

We reviewed 261 patients with 320 Charnley low-friction arthroplasties who had a mean follow-up of 22 years 10 months (20 to 30). Of these, 93.9% considered the operation to be a success; 82.3% were free from pain and 11.6% had occasional discomfort. Satisfactory function was achieved in 59.6% and 62% had an excellent range of movement.

The clinical results did not correlate well with the radiological appearance; radiologically loose components did not affect the clinical outcome. The main long-term problem was wear and loosening of the UHMWPE cup. Our findings suggest that the radiological appearance of the arthroplasty is a more reliable indication of the state of the arthroplasty than the clinical results.


The Journal of Bone & Joint Surgery British Volume
Vol. 81-B, Issue 1 | Pages 54 - 55
1 Jan 1999
Wroblewski BM Siney PD Fleming PA

We report the results of our continued review of 14 hip arthroplasties using alumina ceramic femoral heads with cross-linked polyethylene cups.

There have been no complications and a very low rate of penetration. This was 0.02 mm per year after an initial ‘bedding-in’ period of two years. There has been no change in the mean rate between our earlier study at six years and the current results at 10 to 11 years.

The use of these bearing surfaces appears to reduce the potential amount of polyethylene debris and may provide the next logical stage in the development of the Charnley low-friction arthroplasty.