The aim of this randomised, controlled
Urist performed a similar series of experiments in guinea pigs as Huggins did in his canine model. After two weeks, mesenchymal cells condensed against the columnar epithelium and membranous bone with haversian systems and marrow began to form juxtapose the basement membrane. At no time was cartilage formation noted, only direct membranous bone formation. They also demonstrated the expression of BMP’s in migrating epithelium and suggested that BMP is the osteoinductive factor in heterotopic bone formation.
In relation to the conduct of this study, one or more of the authors is in receipt of a research grant from a commercial source.
In relation to the conduct of this study, one or more of the authors is in receipt of a research grant from a non-commercial source.
In relation to the conduct of this study, one or more of the authors is in receipt of a research grant from a non-commercial source.
In relation to the conduct of this study, one or more of the authors is in receipt of a research grant from a non-commercial source.