Abstract
Introduction and Aims: Cyclic pneumatic pressure applied to the musculature proximal to a fracture of the distal radius has been shown to produce compressive loading of the fracture. The aim of this randomised controlled in vivo study in an ovine model was to investigate the effect of the pneumatic pressure on fracture healing.
Method: Thirty-seven sheep underwent a transverse osteotomy of the right radius. All sheep were managed in a plaster cast and splint to ensure non-weight bearing during rehabilitation. Nineteen of the sheep were randomised to receive cyclic loading by the application of a pressure cuff around the muscles of the proximal forearm deep to the cast. The other 18 sheep acted as controls. The sheep in the experimental group received 120 cyclic loads over two 10-minute sessions each day starting one week post-osteotomy. Sheep from both groups were sacrificed at either four or six weeks. X-rays, ultrasonography, biomechanical testing and histomorphometry were used to assess differences between the groups.
Results: The area of periosteal callus on lateral and antero-posterior x-ray, the peak torsional strength, the fracture stiffness, the energy absorbed over the first 10 degrees of torsion and histomorphometric analysis all showed that the fractures in the group treated with the cyclic pneumatic pressure achieved the same level of union at four weeks as the control group fractures at six weeks (not significantly different p> 0.05). The density of the woven bone in the periosteal callus of the treated sheep was significantly greater than the controls (p< 0.01). Ultrasonography showed no significant difference (p> 0.05) in the amount of muscle wasting between the treated group and the control group.
Conclusion: This study has shown that the rate of healing is enhanced when cyclic pneumatic pressure is applied to the musculature proximal to a transverse fracture of the distal radius in an adult sheep model. There is potential for this treatment to be used in a human population.
These abstracts were prepared by Editorial Secretary, George Sikorski. Correspondence should be addressed to Australian Orthopaedic Association, Ground Floor, The William Bland Centre, 229 Macquarie Street, Sydney, NSW 2000, Australia.
One or more of the listed authors are receiving or have received benefits or support from a recognised academic body for the pursuance of the study.
