Nine patients underwent arthrodesis of the knee using a customised coupled nail (the Mayday arthrodesis nail), five after infected arthroplasty, one following failed arthrodesis, one for intractable anterior knee pain, one for Charcot instability and one after trauma. Comparison was made with 17 arthrodeses, eight undertaken using external fixation, four with dual compression plates, and five with long Küntscher nails. Union was achieved in all patients (100%) at a mean time of ten months using the customised implant. There were no complications despite early weight-bearing. No further procedures were required. This contrasted with a rate of union of 53% and a complication rate of 76% with alternative techniques. Of this second group, 76% required a further operative procedure.

We compared the Mayday arthrodesis nail with other techniques of arthrodesis of the knee. The differences in the need for further surgery and occurrence of complications were statistically significant (p < 0.001), and differences in the rate of nonunion and inpatient stay of less than three weeks were also significant (p < 0.05) using Fisher’s exact test.

We conclude that a customised coupled intramedullary nail can give excellent stability allowing early weight-bearing, and results in a high rate of union with minimal postoperative complications.

A randomised, prospective trial comparing the percutaneous compression plate (PCCP) and the classic hip screw was performed for intertrochanteric fractures of the femur in 108 patients. The PCCP offers the ability to stabilise fractures with a minimal exposure and periosteal stripping thus preserving soft tissue cover.

Over a 19-month period all patients with extra-capsular fractures apart from subtrochanteric and pathologic fractures were included. They were classified as per Evans classification.

The patient’s pre-operative haemoglobin, premorbid mobility, medical and mental status were noted. The duration of the procedure, screening time, blood loss and any technical difficulty encountered along with the post-operative haemoglobin, drainage and transfusion requirements, as well as the length of stay in the orthopaedic unit and total length of stay in the hospital were recorded. Results were analysed using the Chi-square test and Student’s test.

The operating time was significantly longer in the PCCP group (mean 59vs49mins,P< 0.05). There was no significant difference between the two groups with regard to the other parameters measured.

There was no difference in the failure rate (2 cut-outs in the CHS group and one screw back-out in the PCCP.) With the device being of fixed single angled design it proved to be unsuitable for 3 patients.

The PCCP would appear to be as good as the more conventional device though it does not confer the perceived advantages of decreased duration of stay or significant reduction in transfusion requirement which are associated with other percutaneous procedures. The device is a single fixed angle one and is therefore not universally applicable to all patients.

The aim of this study was to investigate the hypothesis that unicompartmental knee replacement (UKR) of a single arthritic tibio femoral compartment can slow the progression of arthritis to the other compartment.

Method: Since 1974, a prospective database has been established in Bristol to register and follow up the results of unicompartmental knee replacement. Forty two prostheses that had survived for more than 10 years were examined using the Ahlbach radiological scoring system and compared to a control group of patients from the Bristol “OA 500” series, in which patients being treated conservatively for gonarthritis were regularly reviewed by clinical scoring and radiological analysis. The groups were sex matched.

All AP and lateral standing knee radiographs at entry and 8 years were scored using the Ahlbach scoring system. The Ahlbach system has been shown to have good inter and intra observer correlation, and to relate closely to pathological findings at operation. An intra and inter observer error study of our results confirmed good correlation.

Results: The groups were well matched but the OA 500 group showed a lower average age, though not a significant difference (62 years compared to 67 years). The lateral compartment of all knees in both groups were Ahlbach grade 0 or 1 group before operation or entry to the OA 500 register.

In the UKR group, four out of 42 knees showed progression of a single Ahlbach grade (9.5%). 2 revisions for arthritic progression were added to this group making a total of six out of 42 (14.3%). In the control group 12 of the 42 knees progressed by one or two Ahlbach grades and a further case underwent surgery making a total of 13 (31%). This difference was significant (p< 0.01).

Conclusion: Recent studies have shown that with a better understanding of design, improved selection of patients and better surgical technique, a UKR can have at least as good, if not better, results than a TKR at 5 year follow up, and has benefits of preservation of anatomy, earlier rehabilitation, preservation of bone stock and easier revision. Our radiological findings in this study will need to be correlated with further randomised prospective clinical studies, but suggest that progression of Osteoarthritis is reduced by UKR, and that this should be an additional stated benefit of this surgical technique.

Introduction: Traditionally adolescent anterior knee pain is considered to be a self limiting condition with no long term sequelae. However recently two publications have suggested the condition may be longer lasting. We wish to suggest that adolescent anterior knee pain may lead to patello femoral arthritis.

Method: We have carried out a comparative study assessing the incidence of previous adolescent anterior knee in patients who underwent patello femoral replacement for isolated patello femoral arthritis and have compared them with a matched group of patients who had medial unicompartmental replacement for isolated medial compartment arthritis without patello femoral disease.

All patients were sent a postal questionnaire enquiring about adolescent anterior knee pain, knee injury and patella instability.

Results: Ninety-three PFR patients and 86 UKR patients replied. The incidence of adolescent AKF and patella instability was higher in the PFR.group.

Conclusion: Adolescent anterior knee pain may not always be a benign self limiting condition since this as well as patella injury and instability was associated with subsequent isolated patello femoral arthritis.

The aim of this study was to demonstrate the effectiveness of a customised coupled arthrodesis nail.

Knee arthrodesis is now infrequently performed and is usually reserved as a salvage for infected Joint arthroplasty or occasionally for intractable pain. Many methods have been used. Recently locked intramedullary coupled nails have gained in popularity. To deal with all size combinations a large inventory is required. We wish to report our series using a customised implant and to compare the outcome with other methods of knee arthrodesis.

Nine patients underwent arthrodesis using this implant, six following infected arthroplasty, two for intractable anterior knee pain and following trauma. Comparison was made with 17 arthrodeses performed since 1993 using external fixation (8), plates (4), and long K-nails (5). Union was achieved in nine patients (100%) at a mean time of 10 months using the customised implant. There were no complications despite early weight-bearing. No further procedures were required. This contrasted with a union rate of 65% with a 76% complication rate using alternative techniques. Seventy six percent of this second group required a further operative procedure.

We conclude that a customised coupled intramedullary nail can give excellent stability allowing early weight-bearing, and results in a high union rate with minimal post-operative complications. The differences in need for further surgery and occurrence of complications were statistically significant (p< 0.001), and differences in in-patient stay and non-union rate were also significant (p< 0.05) using Fisher’s exact test.

The aim of this study was to analyse the kneeling ability of patients before and at one and two years after total (TKR), unicompartmental (UKR) and selective patellofemoral (PFR) knee arthroplasty, for osteoarthritis. Method: Data was prospectively collected on 253 knees, which underwent either TKR, UKR or PFR. A kneeling score was obtained by analysis of the relevant section of the Oxford Knee Score questionnaire. Scores were obtained pre-operatively and at 1 and 2 years post-operatively (minimum score 0, maximum 4). Absolute values and change following arthroplasty were recorded. Correlations with pain and other knee functions were also made.

Results: Kneeling ability prior to surgery was poor in all three groups (mean score 0.7 out of 4) and improved significantly after surgery (mean score at one year 1.13 and at two years 1.46 out of 4) (P< 0.001). Kneeling ability at 1 year differed significantly with operation type (p = 0.02). Kneeling ability improved most in the first year post-operatively but continued to improve between one and two years although the final function was still not good. Kneeling ability was best in UKR and worst in PFR, with the difference between these prostheses being statistically significant (P< 0.001).

Conclusion: Kneeling ability in osteoarthritic knees is poor but improves with arthroplasty. However, the majority of patients will still have difficulty kneeling.

In Total Knee Arthroplasty (TKA) and Total Hip Arthroplasty (THA) the total blood loss is composed of ‘visible’ blood loss from the surgical field and wound drainage, and blood loss into the tissues which is ‘hidden’. Blood management should be aimed at addressing the total blood loss.

56 TKAs and 46 THAs were prospectively studied. TKAs were performed with tourniquet. After tourniquet release, all drained blood was salvaged and significant volumes reinfused. No reinfusion was used for THAs.

The true total blood loss was calculated in the following way:

Patient Blood Volume (PBV) is: [1]

PBV = k1 x height3 + k2 x weight + k3

Therefore patient total Red Blood Cell volume (RBCv) is:

RBCv = PBV x Hct. (where Hct is Haematocrit)

Total RBCv loss = PBV x (Hct preop – Hct postop) + ml RBC transfused

The result is reconverted to Whole Blood volume.

Hidden Loss = Total Loss – Visible Loss.

In TKA, the mean total true blood loss was 1474ml. The mean hidden loss was 735ml. Therefore hidden loss is 50% of the total loss and the total true loss following TKA is twice the visible volume. In THA, the mean total true blood loss was 1629ml. The mean hidden loss was 343ml.

Thus hidden loss in THA is much smaller. (21%) Total loss is 1.3 times the visible loss. In the TKA group, comparing patients with large losses receiving reinfusion and those with small losses not receiving reinfusion, the proportion of total true loss which was hidden was the same, at 50%.

Patients with Body Mass Index (BMI) > 30 were compared with those with a BMI < 30 and no correlation was found between BMI and Hidden Loss.

Joint Replacement Surgery involves a ‘hidden’ blood loss which is not revealed and cannot be measured or reinfused in practice, but which should be taken into account when planning blood loss management. In TKA it is substantial. In THA it is much smaller and probably not of as much clinical concern. Hidden loss is no greater in the Obese patient.

Aim: To assess the functional results of revision TKR with the PFC/TC3 system, and to correlate this with the reasons for revision and restoration of joint height.

Method: One hundred and fifty three patients underwent revision TKR using the PFC/TC3 system. Data was prospectively collected (using the Bristol Knee Score) pre-operatively and at a mean of 4.2 years post-revision. Forty three revisions were for infection and 81 revisions were for aseptic loosening. Measurements of the joint height were made pre and post-operatively using Figgie’s method and were divided into three groups: lower by more than 5mm, restored and elevated more than 5mm. Use of distal augments and polyethylene thickness were recorded.

Results: The mean pre-op function score was 12 and post-operatively was 19 for the infection group and 20 for the aseptic loosening group. Revision after initial UKR gave a mean score of 21, while revision after TKR gave a mean score of 18 (max 27). Knees in which the joint line was elevated by more than 5 mm had a mean score of 17 while those where the joint line was restored had a mean score of 1 9. Recent increasing use of distal augments improved the joint line and results.

Conclusion: Revision using the PFC/TC3 system produced acceptable medium term functional results and good survival. Better restoration of joint line and functional results were achieved by distal femoral rather than proximal tibial augmentation.

Objective: To report the survivorship rate and clinical outcome of a large series of lateral unicompartmental replacements.

Method: 88 lateral St Georg Sled LTKRS were performed between 1978 and 1999. Clinical and radiological data was prospectively recorded at regular follow up and only 5 knees were lost during the 22 year period.

Results: 15 knees were revised after an average of 8 years. (eight for progressive arthritis, six for loosening and four for femoral fracture) 29 patients (30 knees) died during the course of the study. At final follow up (average 9 years) 50 of the 63 remaining knees were rated as good or excellent, nine as fair and nine poor. The mean range of flexion was 110°.

At 10 years the cumulative survival rate was 83% and at 15 years 78% (10 knees at risk). The “worst case scenario” where knees with pain or lost to follow up are added to revisions shows a 10 year survivorship of 74%.

Conclusion: Although the results are not as good as medial UKR. These clinical outcomes suggest that the conservative surgical procedure of lateral UKR with the fixed bearing St George Sled prosthesis can give acceptable results in the uncommon situation of severely symptomatic isolated lateral tibio femoral arthritis.

Purpose: To compare the ten-year survivorship results of an established total and medial compartment knee replacement performed in a single centre over an eighteen year period.

Method: Since 1978 knee replacements have been prospectively recorded in Bristol on a database. Regular clinical and radiological review has been undertaken every two or three years up to twenty years. 408 medial St Georg Unicompartmental replacements and 531 Kinematic total knee replacements have been subject to survivorship analysis using three failure end points. One - revision or removal of the implant. Two – revision or removal and moderate or severe pain. Three – the worst case including all patients lost to follow-up.

Results: The follow-up rate was 97% in both groups. 212 patients (562 knees) died and 31 patients (35 knees) were lost to follow-up. At ten years 25 medial Sled and 20 Kinematic knee arthroplasties had been revised. There was no significant difference (p > 0.05) in the number of good and excellent results. The mean range of movement at the last follow-up was 109 degrees for the medial Sled and 100 degrees for the Kinematic (p< 0.01). 94% of the medial Sled patients obtained a range of movement equal to or greater than 90 degrees whereas only 84% of Kinematic patients obtained this range (p < 0.05).

The ten-year survivorship figures were similar for both groups. Revision as the end point was 87.5% for the medial Sled and 89.6% for the Kinematic knees. When moderate and severe pain was considered in addition to revision ten-year survivorship was 79.4% in both groups. The worst case survivorship was also 74% in both groups.

Conclusion: The ten-year survivorship results of a fixed bearing, non-congruous, Unicompartmental arthroplasty are as good as those of a total knee replacement when performed in a single centre by two consultant surgeons and a variety of trainees. The advantages of a more rapid recovery and better quality result are offset by an easier though slightly higher revision rate.

We describe 88 knees (79 patients) with lateral unicompartmental osteoarthritis which had been treated by the St Georg Sled prosthesis.

At a mean follow-up of nine years (2 to 21) 15 knees had revision surgery, nine for progression of arthritis, six for loosening, four for breakage of a component and four for more than one reason. Six patients complained of moderate or severe pain at the final follow-up. Only five knees were lost to follow-up in the 21-year period.

We performed survivorship analysis on the group using revision for any cause as the endpoint. At ten years the cumulative survival rate was 83%, and at 15 years, when ten knees were still at risk, it was 74%.

Based on our clinical results and survival rate the St Georg Sled may be considered to be a suitable unicompartmental replacement for isolated lateral compartment osteoarthritis.

Traditional dogma states that anterior knee pain in adolescence does not lead to patello-femoral arthritis. However analysis of 642 new knee referrals seen in one year showed that over 25% had anterior knee pain and that patients were of all ages. This lead to us questioning whether anterior knee pain or adolescent chondromalacia patellae is in fact a benign self limiting condition.

Method: A postal questionnaire was sent to 150 patients who had undergone isolated patello femoral replacement (PFR) enquiring about patella problems earlier in life. The same questionnaire was sent to a matched group of patients who had undergone unicompartmental replacement; because of the selection policy of the unit, these would not have had changes of patellofemoral arthritis.

Results: 118 patients who had undergone PFR retumed the form. 107 were female; the average age at surgery was 66 years. 26 (22%) reported adolescent anterior knee pain at an average age of 18. 112 forms were returned form the UKR group in which females predominated and who had an average age at surgery of 67 years. Only 7 (6%) reported adolescent anterior knee pain, at an average age of 19. 16 (14%) of the PFR group reported adolescent patella instability as opposed to 1 on the UKR group.

Discussion: The finding that significantly more patients with isolated patello-femoral arthritis had suffered from adolescent anterior knee pain suggests a possible causal relationship. Further long-term studies are needed to determine whether adolescent anterior knee pain is benign, as traditionally believed, or whether certain subsets are precursors of patello-femoral arthritis.

Purpose: This study analyses the kneeling ability of patients following Unicompartmental knee replacement (UKR), Patellofemoral replacement (PFR) and Total knee replacement (TKR).

Method: Data was prospectively collected on 272 knees (254 patients) that had undergone various forms of arthroplasty procedures for osteoarthritis of the knee. All patients completed the Oxford Knee Questionnaire preoperatively and 1 year postoperatively, thus graded their kneeling ability into one of 5 categories. Absolute values and change following arthroplasty were recorded. In addition the reported kneeling ability of 75 patients was checked by clinical examination.

Results: Preoperatively only 2% of all patients could kneel with PFR group being more able than the others (UKR 0%, TKR 0% and PFR 6%). In all groups the kneeling ability was better one year following replacement than preoperatively (23% of UKR, 18% of TKR and 9% of PFR) being able to kneel with little or no difficulty.

Conclusions: No form of arthroplasty used resulted in good kneeling ability, though this function was always improved particularly by UKR. Good range of movement and younger age appeared to correlate with better kneeling ability but many patients thought they had been told not to kneel and reported less ability than they demonstrated on examination. Instruction to avoid kneeling seems unnecessary.

Aim: MRI examination of tibial tunnel enlargement after hamstring ACL surgery.

Methods and Results: 101 primary hamstring ACL reconstructions were carried out employing a transtibial over-the-top route with fixation provided by the Soffix buttonhole polyester double loop device (1186 N mean UTL to failure with young human cadaveric STG tendons). 24 were reviewed and bony tunnel enlargement was evaluated. 18 prospective reconstructions at 4 months and 6 randomly selected cases at a mean of 14 months were subjected to MRI scanning performed perpendicular to the tibial tunnel axis and the cross sectional area (CSA) was calculated with a computer programme.

In 7 cases there was no enlargement, in 5 cases there was cylindrical enlargement, in 12 cases there was conical enlargement but no cavitation was noted. A maximum mean CSA of 33% ± 38.84 sd was noted at the upper tibial tunnel exit whilst the CSA increase at the distal tibial tunnel entrance was 13% ± 16.77 sd.

In addition the MRI scan showed no evidence of excessive granulation tissue ingrowth or synovial fluid between the graft and the tunnel wall. It would appear that micro-motion which is a major factor in tunnel enlargement is eliminated by the combination of a tight fitting graft, the strength and stiffness of the fixation device and highly accurate, low stress placement of the tibial tunnel. Post operative KT 2000 arthrometric testing of the mean side to side difference (SSD) was 1.71 mm ± 1.82 sd confirming that the graft remained stiff in vivo.

Conclusion: We concluded that our technique avoids excessive tunnel enlargement and leads to greater post-operative graft stiffness than that reported in other series, where hamstring reconstruction has been employed.

We have studied the long-term outcome of 408 primary medial St George Sled unicompartmental arthroplasties of the knee and 531 primary Kinematic total knee arthroplasties using survivorship analysis. The operations were performed by a number of surgeons under the supervision of two consultants at one orthopaedic centre. Prospective clinical assessment was carried out before and at 2, 5, 8, 10, 12 and 15 years after operation. Failure was defined as follows: revision or removal of the implant; the presence of moderate or severe pain; or ‘worst-case’ with all patients lost to follow-up.

Cumulative survival rates at ten years were calculated using life tables. The follow-up rate was 97%. At ten years, 25 medial sled arthroplasties and 20 Kinematic knee arthroplasties had been revised. With revision or removal as the survivorship endpoint at ten years there was a success rate of 87.5% for the medial sled and 89.6% for the Kinematic knee arthroplasty. When moderate or severe pain was included these rates became 79.4% for both arthroplasties. There was no statistically significant (p > 0.05) difference between the rates of survival for the two arthroplasties using either of the endpoint criteria.

Good or excellent results were recorded for 77.9% of the medial sled knees and 75.1% for the Kinematic knees. The former had 93.8% of cases with a final range of movement in excess of 90° compared with 83.7% for the Kinematic knees (p < 0.01). We conclude that at a single orthopaedic centre in the UK, the St Georg Sled medial compartment arthroplasty for appropriate specific indications offers predictable survivorship at ten years which is comparable with that of the Kinematic total knee arthroplasty.

We performed a randomised, prospective trial in 111 patients with intertrochanteric fractures of the hip comparing the use of the Gotfried percutaneous compression plate (PCCP) with that of the classic hip screw (CHS). Blood loss and transfusion requirement were less in the PCCP group but the operating time was significantly longer. The complication rate after operation was similar in both groups, and at a minimum follow-up of six months there was no difference in the rates of fracture healing or implant failure. The PCCP gives results which are similar to those obtained with a conventional device. Its suggested advantages seem to be theoretical rather than practical and, being a fixed-angle implant, it is not universally applicable.

We present a prospective review of the outcome of 76 Lubinus patellofemoral arthroplasties carried out in 59 patients between 1989 and 1995. At a mean follow-up of 7.5 years, 62 knees in the 48 patients were reviewed; 11 patients (14 knees) had died. None was lost to follow-up.

The clinical outcome using the Bristol Knee Scoring system was satisfactory in 45% of the cases. Maltracking of the patella, resulting in lateral tilt, subluxation and polyethylene wear, was the most common complication (32%). Revision surgery was carried out in 21 knees (28%) giving a cumulative survival rate of 65% (confidence interval (CI) 49 to 77) at eight years. The survival rate for revision and moderate pain was 48% (CI 36 to 59) at six years. Progression of arthritis was seen in seven cases (9%). In five of these (6.5%), the symptoms were severe enough to need revision surgery. Due to the high proportion of unsatisfactory results, we have discontinued the use of this prosthesis.

Failure of a unicompartmental knee replacement (UKR) may be caused by progressive osteoarthritis of the knee and/or failure of the prosthesis. Limb alignment can influence both of these factors. We have examined the fate of the other compartments and measured changes in leg alignment after UKR.

A total of 50 UKRs was carried out on 45 carefully selected patients between 1989 and 1992. At operation, deliberate attempts were made to avoid overcorrection of the deformity. Four patients died, one patient was lost to follow-up and two knees were revised before review which was at a minimum of five years. Standard long-leg weight-bearing anteroposterior views of the knee and skyline views of the patellofemoral joint were taken before and at eight months and five years after operation. The radiographs of the remaining 43 knees were reviewed twice by blind and randomised assessment to measure the progression of osteoarthritis within the joints. Overcorrection of the deformity in the coronal plane was avoided in all but two knees. Only one showed evidence of progression of osteoarthritis within the patellofemoral joint, and this was only identified in one of the four assessments. Deterioration in the state of the opposite tibiofemoral compartment was not seen. Varus deformity tended to recur. Recurrent varus of 2° was observed between eight months and five years after operation. There was no correlation between the postoperative tibiofemoral angle and the extent of recurrent varus recorded at five years. Changes in alignment may be indicative of minor polyethylene wear or of subsidence of the tibial component.

The incidence of progressive osteoarthritis within the knee was very low after UKR. Patients should be carefully selected and overcorrection of the deformity be avoided.

Patella infera may occur after reconstruction of the anterior cruciate ligament (ACL), high tibial osteotomy and total knee replacement (TKR). Restriction of movement of the knee and pain may result. Our aim was to compare the incidence and to assess the effects of patella infera after TKR and unicompartmental knee replacement (UKR).

We reviewed radiographs of the knees of 84 patients who had had either TKR or UKR as part of a randomised, controlled trial. The length of the patellar tendon was measured on serial radiographs taken before, at eight months and at five years after operation.

There was no significant change in the length of the patellar tendon after UKR, but a significant reduction was observed after TKR. Five years after the operation, the shortening of the tendon had increased to a mean of 3.5 mm. Of the knees with TKR reviewed at five years, 34% developed patella infera, defined as 10% or more of shortening, compared with 5% of those with UKR. Shortening was greatest in those knees which had required a lateral release; in this subgroup the mean shortening was 7.2 mm. Shortening correlated with restriction of movement and pain in the knee.

Our study has shown that patella infera develops in most patients after TKR with lateral release, and in approximately 25% of patients after TKR without this additional procedure. Patella infera rarely occurs after UKR. It is associated with restriction of movement and pain in the knee. It may be an effect of the more extensive exposure required to perform TKR and may, in part, explain the better clinical results of UKR.

We randomised 102 knees suitable for a unicompartmental replacement to receive either a unicompartmental (UKR) or total knee replacement (TKR) after arthrotomy. Both groups were well matched with a predominance of females and a mean age of 69 years.

Patients in the UKR group showed less perioperative morbidity, but regained knee movement more rapidly and were discharged from hospital sooner.

At five years, two UKRs and one TKR had been revised; another TKR was radiologically loose. All other knees appeared to be clinically and radiologically sound.

Pain relief was good in both groups but the number of knees able to flex ≥ 120° was significantly higher in the UKR group (p < 0.001) and there were more excellent results in this group.

Our findings have shown that UKR gives better results than TKR and that this superiority is maintained for at least five years.

We have carried out a randomised, controlled trial on 70 patients having unilateral total knee replacement in which transfusion was either with homologous bank blood or by reinfusion of unwashed blood salvaged after operation.

No complications or adverse effects were observed from reinfusion. The need for bank blood was reduced by 86% in the reinfusion group but, more importantly, the number of infective episodes was significantly less when the use of bank blood was avoided. The mean length of stay in hospital was also reduced by more than two days.

Nerve injury is a rare complication of total hip replacement which may be related to the exposure used for the operation. The posterior approach is traditionally associated with injury to the sciatic nerve. We have compared the incidence of nerve injury after primary total hip replacement (THR) using either a posterior or a direct lateral approach.

We studied 42 consecutive patients undergoing primary total hip replacement. The surgeons used a posterior (22 patients) or direct lateral (20 patients) approach in accordance with their normal practice. The obturator, femoral, posterior tibial and common peroneal nerves were assessed clinically and electrophysiologically by electromyography (EMG) and measurement of the velocity of nerve conduction before operation and at four weeks after.

All patients were free from symptoms of nerve injury after operation but five lesions were identified in four patients by the electrophysiological studies; the obturator nerve was involved in two, the femoral in one, the common peroneal in one and the posterior tibial in one. All these injuries occurred using the lateral approach.

Clinical assessment alone underestimates the incidence of nerve injury complicating THR. Our study does not confirm the association of nerve injury with the posterior approach which had been described previously.

We report a prospective case-controlled study which compared the outcome of knee replacement in seriously deformed and slightly deformed knees. There were 51 knees with varus or valgus deformity greater than 20 degrees matched for age, gender, disease, type of prosthesis and time of operation with a control group in which the alignment of the leg was within 5 degrees of normal. The clinical outcome at a mean 5.5 years was similar in the two groups. Some deformity persisted in 14 patients in the first group, 13 of whom were initially in valgus. These patients had a significantly poorer mean clinical outcome. Lateral dislocation or subluxation of the patella was found in four knees, all of which had had valgus deformity of 30 degrees or more.

The stabilising effects on the glenohumeral joint of each of the rotator-cuff muscles and of the biceps were studied with the arm in abduction and external rotation in 13 cadaver shoulders. The muscles were loaded one at a time with forces proportional to their cross-sectional areas. We recorded the positions of the humeral head before and after the application to the humerus of an anterior force of 1.5 kg. When the capsule was intact, the anterior displacement with the subscapularis loaded was significantly larger than with the other muscles loaded (p = 0.0009). With the capsule vented, the displacement with the biceps loaded was significantly smaller than that with the subscapularis loaded (p = 0.0052). After creating an imitation Bankart lesion, the displacement with the biceps loaded was significantly less than with any of the rotator-cuff muscles loaded (p = 0.0132). We conclude that in the intact shoulder, the subscapularis is the least important anterior stabiliser, and that the biceps becomes more important than the rotator-cuff muscles as stability from the capsuloligamentous structure decreases. Strengthening of the biceps as well as the rotator-cuff muscles should be part of the rehabilitation programme for anterior shoulder instability.

We studied the mechanical properties of cartilage from the apparently unaffected compartment of knees with unicompartmental osteoarthritis (OA). Plugs of cartilage and subchondral bone, 8 mm in diameter, were obtained from the tibial plateau of seven patients treated by total knee replacement. Control specimens were obtained from eight cadaver knees of similar age. Specimens were loaded by a plane-ended indentor in a hydraulic materials testing machine; we measured thickness, 'softness', rate of creep, and compressive strength of the articular cartilage. We found that the 'unaffected' cartilage from OA knees was significantly thinner and softer than control cartilage, and it was slightly, although not significantly, weaker. We conclude that the apparently unaffected cartilage in knees with unicompartmental OA is mechanically inferior to normal cartilage, even although clinically, radiologically and morphologically it appears to be sound.

This new blood test for infection is based on the phenomenon of leukergy in which white cells agglomerate in the peripheral blood of patients with inflammatory diseases. It was used in 26 patients with proven bone or joint infection and was positive in 25. The leukergy test was more accurate than the ESR, white cell count or blood culture. The percentage of cells agglomerated correlated with the clinical severity of the infection and the test detected reactivation of the septic process better than the other haematological tests. It is a rapid and inexpensive method which is useful in the diagnosis and management of bone and joint infections.

We studied the contributions of the long and short heads of the biceps (LHB, SHB) to anterior stability in 13 cadaver shoulders. The LHB and SHB were replaced by spring devices and translation tests at 90 degrees abduction of the arm were performed by applying a 1.5 kg anterior force. The position of the humeral head was monitored by an electromagnetic tracking device with or without an anterior translational force; with 0 kg, 1.5 kg or 3 kg loads applied on either LHB or SHB tendons in 60 degrees, 90 degrees or 120 degrees of external rotation; and with the capsule intact, vented, or damaged by a Bankart lesion. The anterior displacement of the humeral head under 1.5 kg force was significantly decreased by both the LHB and SHB loading in all capsular conditions when the arm was in 60 degrees or 90 degrees of external rotation. At 120 degrees of external rotation, anterior displacement was significantly decreased by LHB and SHB loading only when there was a Bankart lesion. We conclude that LHB and SHB have similar functions as anterior stabilizers of the glenohumeral joint with the arm in abduction and external rotation, and that their role increases as shoulder stability decreases. Both heads of the biceps have been shown to have a stabilising function in resisting anterior head displacement, and consideration should therefore be given to strengthening the biceps during rehabilitation programmes for chronic anterior instability of the shoulder.

We conducted a prospective randomised trial to compare the results of anatomical reduction and medial displacement osteotomy in 127 consecutive patients with unstable intertrochanteric fractures, of whom 109 completed the study. After an average follow-up of 11 months, we found no significant differences in walking ability, social status or failure of fixation in the two groups. Postoperative complication rates and the early mortality rate were not significantly different, but operating time and blood loss were significantly higher in the osteotomy group. With the use of modern sliding hip screws, medial displacement osteotomy is rarely indicated for unstable intertrochanteric fractures.

We have reviewed 185 articles published since 1966 to assess the scientific evidence for methods of treatment for lateral epicondylitis of the elbow. Of the 185 articles, 78 discussed treatment, but since the natural history of the syndrome is uncertain we considered only those series with concurrent control groups. Only 18 of these were randomised and controlled studies. We then graded these papers for scientific validity, using the methods of Chalmers et al (1981). The mean score of the 18 articles was only 33%, with a range from 6% to 73%. A minimum of 70% is required for a valid clinical trial, and we therefore concluded that there was insufficient scientific evidence to support any of the current methods of treatment. There were too many methodological differences to allow a quantitative meta-analysis, but our qualitative review established the importance of the natural evolution of the syndrome and of the placebo effect of all treatments. Properly designed, controlled trials are needed.

Diaphyseal fractures of the tibia in 80 patients were treated by external skeletal fixation using a unilateral frame, either in a fixed mode or in a mode which allowed the application of a small amount of predominantly axial micromovement. Patients were allocated to each regime by random selection. Fracture healing was assessed clinically, radiologically and by measurement of the mechanical stiffness of the fracture. Both clinical and mechanical healing were enhanced in the group subjected to micromovement, compared to those treated with frames in a fixed mode possessing an overall stiffness similar to that of others in common clinical use. The differences in healing time were statistically significant and independently related to the treatment method. There was no difference in complication rates between treatment groups.

A new method of recording the three-dimensional anatomy of the proximal femur from a single anteroposterior radiograph is described. This technique shows that in Perthes' disease the femoral head and neck are in significant anteversion and true varus. This anatomical configuration may be important in the pathogenesis and treatment of this disorder.

The effect of hypobaric spinal anaesthesia or narcotic-halothane-relaxant general anaesthesia on the incidence of postoperative deep vein thrombosis was studied in 140 elective total hip replacements in a prospective randomised manner. Deep vein thrombosis was diagnosed using impedance plethysmography and the 125I fibrinogen uptake test, combined, in selected cases, with ascending contrast venography. The overall incidence of deep vein thrombosis was 20%. Nine patients (13%) developed deep vein thrombosis in the spinal group and nineteen (27%) in the general anaesthetic group (p less than 0.05). The incidences of proximal thrombosis and of bilateral thrombi were also less with spinal anaesthesia than with general anaesthesia. It is concluded that spinal anaesthesia reduces the risks of postoperative thromboembolism in hip replacement surgery. The presence of varicose veins, being a non-smoker and having a low body mass index were associated with an increased incidence of deep vein thrombosis.

We have reviewed the results of treating 75 fractures of the proximal femoral shaft in the presence of a cemented femoral prosthesis. A simple radiographic classification into four types is proposed, and suggestions are made on the appropriate management of each. Comminuted fractures around the implant need early revision, whilst spiral fractures in this region may be treated conservatively or by operation. Transverse fractures at the level of the tip of the prosthesis are difficult to manage, and may require open reduction and internal fixation.

Antibiotic levels in bone and fat were measured in patients undergoing knee replacement to determine the time that should elapse between intravenous injection and tourniquet inflation. The tissue levels increased progressively with time, and there was wide variation in absorption rate between patients and between the two cephalosporins assessed. Five minutes should probably be left between systemic injection and inflation of the tourniquet, though two minutes may be long enough for drugs which are rapidly absorbed.

This paper reports the results of bone scans on 78 painful feet. Scanning helped in the diagnosis of persistent foot pain following injury and it enabled stress fractures, fractures of the sesamoids and subtalar arthritis to be diagnosed earlier. It reliably excluded bone infection and was useful as a screening test when radiographs were normal.

The results of excision of the distal ulna in 34 wrists of 25 patients with chronic rheumatoid arthritis of the distal radio-ulnar joint were reviewed. Rest pain had been cured or relieved in 77%, pain on pronation-supination in 86%, and limitation of pronation-supination in 90%, while 88% of the patients graded the result as excellent or fair. Despite this marked relief of symptoms, function of the upper limb was improved in only 25% of patients and remained unchanged in 60%. Ulnar subluxation of the carpus had occurred in 24% but seemed to be related to the destructive disease process rather than to the operation itself. The length of ulna resected was not related to the outcome of the operation.

An unusually wide pneumatic tourniquet has recently become available; we provide a simple formula for its use with a low but effective inflation pressure. A prospective, randomised and controlled trial in 600 lower limb and 150 upper limb operations is reported. The wide tourniquet (12.5 cm) was as effective at low pressure as was a conventional tourniquet (9 cm) inflated to significantly higher pressures. Fewer patients suffered from painful paraesthesiae after operation using the broad, low-pressure tourniquet.

We have made a retrospective comparison between the results of 49 high tibial osteotomies and 42 unicompartmental replacement arthroplasties performed for the treatment of osteoarthritis of the knee, assessed 5 to 10 years after operation. The type of operation depended on the policy of the consultant responsible for treatment but analysis of the pre-operative findings showed that the two groups were sufficiently similar for direct comparison between them. In the replacement group, 32 (76%) were good, 4 were fair, 3 were poor and 3 had been revised. In the osteotomy group 21 (43%) were good, 11 were fair, 7 were poor and 10 had been revised. It was concluded that, in this series, the results of unicompartmental replacement were significantly better and that this group had shown no sign of late deterioration.

A model of tourniquet ischaemia was developed in the hind limb of the rat, and the metabolic changes that occurred in the calf muscles were monitored by the non-invasive technique of phosphorus-31 nuclear magnetic resonance spectroscopy. During ischaemia the intramyocellular pH became acidic as the level of phosphocreatine declined and that of inorganic phosphate rose. Phosphocreatine was no longer detectable after approximately 2 hours and ATP was depleted after approximately 3.5 hours. Metabolic recovery was rapid (1 hour) if ATP was present when the tourniquet was released but was prolonged (3 or more hours) if ATP was depleted. Hourly release of the tourniquet for 10 minutes ensured the maintenance of ATP and rapid metabolic recovery. Release for intervals of only 5 minutes did not have the same protective effect and in fact worsened tissue pH during the period of tourniquet ischaemia. Heparin and corticosteroids were without effect during and after periods of tourniquet ischaemia.

Five elderly patients with chronic pyrophosphate arthropathy developed stress fractures of the tibia. All patients had deformed, painful knees with the result that their increasing symptoms were not readily attributed to a stress fracture. Such a possibility should be considered in patients with chronic pyrophosphate arthropathy since early recognition makes management of the stress fracture easier.

Six different conditions of non-infective bone and joint pathology have been seen amongst 67 patients with diabetic neuropathy. The characteristics of each are described. Not all the conditions require treatment but they should be differentiated from osteomyelitis. Charcot osteoarthropathy is the most common condition seen but spontaneous fractures and dislocations generally present greater therapeutic problems. The aim of treatment should be to obtain a stable foot in which there is no undue pressure on the skin from a bony prominence.

The clinical details of six patients who developed spontaneous dislocations in the foot or ankle are presented. All were shown to have diabetic neuropathy. This previously unreported condition can occur with a short history of diabetes. Some cases can be managed without operation, though arthrodesis probably offers the best chance of obtaining a stable foot of satisfactory shape.

Intertrochanteric osteotomy gives compensatory correction for the severely slipped upper femoral epiphysis without endangering its blood supply. The results of thirty-five such osteotomies carried out over an eighteen-year period are reviewed. The indication for operation was a chronic slip of a third or more of the growth plate in the lateral radiograph. The mean age at operation was fourteen years and the mean follow-up period seven and a half years. The results showed that even a moderate correction of deformity as shown by the radiograph could produce a hip with a functionally satisfactory range of movement. Chondrolysis was the most serious complication and occurred in four hips. The radiological results are discussed in relation to details of operative technique and also to long-term prognosis.