There was an increased incidence of AVN after closed than open reduction but this became not statistically significant when one study with a markedly higher reported incidence of AVN was excluded. The difference in the incidence of NU and AVN following early (<
12 hours) or late (>
12 hours) surgery was not significant for either NU or AVN.
Conventional treatment for nondisplaced intracapsular hip fractures is with cannulated screws. Some authors have argued that in the older patient a hemiarthroplasty offers a better outcome even in the case of a nondisplaced fracture. We have compared the outcomes of an age, sex &
co-morbidity matched cohort of 346 patients who have had their nondisplaced hip fracture treated using cannulated screws with a group of 346 patients who have had a displaced fracture treated with a hemi-arthroplasty. The average age of the patients studied was 80.8 years. All operations were carried out at Peter-borough District Hospital and the follow up data was collected as part of the hip fracture project. Operation time, hospital stay and peroperative complication rate are less for the fixation group. They also have better outcomes in terms of pain, use of walking aids and mobility scores at one year. Mortality is 4% less at one year in the patients treated with screws and this, again, is statistically significant. There is no difference in terms of residential status at one year. In patients where the fracture is initially treated with cannulated screws the reoperation rate is considerably higher (17 % versus 6%) but length of stay is less for secondary procedures. We feel that there is little evidence to justify the use of hemi-arthroplasty in nondisplaced femoral neck fractures in patients of any age.
Radiographic analysis suggests that the position of the screws on the AP view (superior, middle, inferior or spread) did not alter the outcome significantly. However three factors were related to lower risk of non-union on the lateral view: the closer the middle screw to the center of the head (p<
0.04), the more anterior the anterior screw (p<
0.008), and the greater the ‘spread’ between the anterior and posterior screws (p<
0.005).
Open operative treatment compared with non-operative treatment was associated with a lower risk of re-rupture (odds ratio (OR) = 0.25, 95% confidence interval (CI) = 0.1–0.6, p=0.003) but a higher risk of other complications including infection, adhesions and disturbed sensibility (OR = 14.1, 95%CI = 6.3–31.7, p<
0.00001). Open versus percutaneous operative surgical repair was associated with a longer operation duration and higher risk of infection (OR = 12.9, 95%CI = 1.6–105.6, p=0.02). Patients splinted with a functional brace rather than a cast post-operatively tended to have a shorter in-patient stay, less time off work, quicker return to sporting activities and fewer reported complications (p=0.0003). Because of the small number of patients involved no definitive conclusions could be made regarding different operative techniques and different non-operative regimes.
Previous studies on the timing of hip fracture surgery provide limited and conflicting evidence as to whether early operative intervention influences length of hospital stay, functional outcome and mortality rate. The aim of this study was to determine in a large, consecutive and prospectively followed group of patients the effect of a delay to surgery other than for medical reason. Patients who met the following criteria were included in the study: 1) Fragility fracture of the proximal femur. 2) Age over 60. 3) Complete data sets. 4) Complete follow up. Excluded patients were: 1) Younger than 60 years of age. 2) Conservative fracture treatment. 3) Pathological fracture. 4) Delay from admission to surgery for any medical reason. All patients were subdivided into six groups according to the delay between admission and operation (A:1–12 hours, B:13–24 hours, C:25–36 hours, D:37–48 hours, E:49–72 hours, F:73 + hours). All patients were followed up for one year or until death. Data on the mean length of hospital stay and the discharge destination as a parameter for the functional outcome were analysed in each of the six groups. A total of 3628 patients met the inclusion criteria. The average age was 81 years. 95.2% of patients were operated on between 1 and 48 hours after the admission, and 4.8% between 49 or more hours after the admission. Reason for delay was either lack of theatre time or unavailability of a surgeon or an anaesthetist. Statistical analysis with the unpaired t-test showed a significant difference in the hospital length of stay of 21 days for patients operated within 48 hours of admission versus 32 days for patients operated after 48 hours (p The functional outcome was significantly worse in the group with a delay of more than 48 hours with only 71% of patients discharged to their own home (86% in the early group, p<
0.0001). This study provides further and conclusive evidence that early operative intervention in elderly patients with fragility fractures of the proximal femur results in a decreased hospital stay and a better functional outcome.
There was an increased incidence of AVN after closed than open reduction (P= 0.0005, RR = 2.77, 95% CI: 1.45 to 5.29) but this became not statistically significant when one study with a markedly higher reported incidence of AVN was excluded (P = 0.07, RR= 1.85, 95% CI: 0.93 to 3.68). The difference in the incidence of non-union and AVN following early (<
12 hours) or late (>
12 hours) surgery was not significant for either non-union or AVN (13/110 [11.8%] versus 3/60 [5.0%], p=0.18, RR2.36, CI 0.70 to 7.97 for non-union, 15/110 [13.6%] versus 9/60 [15.0%], p=0.82, RR=0.91, CI 0.42 to 1.95 for AVN).
Areal BMD (aBMD) is relatively poor at discriminating those patients at risk of hip fracture. This study tested the hypothesis that a measure of bending resistance, cross section moment of inertia (CSMI) and section modulus, derived from 3D peripheral quantitative computed tomography (pQCT) images made ex-vivo, would discriminate cases of hip fracture from controls better than areal bone mineral density. The biopsies were from (n = 20, F) subjects that had suffered an intracapsular hip fracture. The control material (n = 23, F) was from post-mortem subjects. Serial pQCT 1mm thick cross-sectional images using the Densiscan 1000 pQCT clinical forearm densitometer were obtained, and matched for location along the neck. The image voxels were converted to units of bone mass, which were then used to derive the mass weighted CSMI (MWCSMI), section modulus and areal bone mineral density, (see Table). The aBMD results showed that the difference between the means of the fracture cases compared to the controls was 9.9% (−0.061g/cm2; +0.0055g/cm2, −0.127g/cm2; 95% confidence interval). However, the MWCSMI was 29.5% (−5966mm4; −8868mm4,−3066mm4; 95% confidence interval) lower in the fracture cases compared to the controls, while section modulus was 32.5% (−242mm3; −133mm3, −352mm3 95% confidence interval) lower. When presented as Z scores the fracture cases had considerably lower section modulus Z scores (mean −1.27 SD, p=0.0001) than aBMD – Z scores (mean −0.5 SD, p=0.07). To simulate the forces experienced during a sideways fall, the model’s neutral axis was rotated by 210°. The results were similar for section modulus to those at 0°. This study suggests that biomechanical analysis of the distribution of bone within the femoral neck may offer a marked improvement in the ability to discriminate patients with an increased risk of intracapsular fracture. Progress towards implementing this form of analysis in clinical densitometry should improve its diagnostic value.
The displaced intracapsular fracture in the elderly has frequently been termed the ‘unsolved’ fracture because of the debate as whether the femoral head should be preserved or replaced. To answer this question 413 patients aged over 70 years with a displaced intracapsular fracture were entered into a prospective randomised trial, to treatment with either an uncemented Austin Moore hemiarthroplasty or reduction and fixation with three cancellous screws. Pathological fractures, Paget’s disease and rheumatoid arthritis patients were excluded. Analysis of pre-operative characteristics of patients showed there was no significant difference between the two groups. Mean follow-up of surviving patients was 827 days. Internal fixation resulted in a reduced mean operative time (22 versus 47 minutes), operative blood loss (23ml versus 171mls) and transfusion requirements. There was no significant differences in the incidence of post-operative complications between treatment other than and increased risk of wound sepsis for arthroplasty (4/207 versus 0/206 deep wound infections). There was a consistent tendency to a marginally lower mortality following internal fixation (15.5% versus 12.7% at 90 days). Six patients in the arthroplasty group required revision, four for loosening, one for sepsis and one for fracture around the implant. Non-union occurred in 64(31%) of those treated by internal fixation. Most of these patients had conversion to arthroplasty. Other complications of internal fixation requiring secondary operations were avascular necrosis (4 cases), fracture below implant (1 cases) and removal for painful screw heads (7 cases). Functional assessment of the survivors at one year from injury showed no significant difference between the two groups for pain or change in mobility. These results indicate that arthroplasty for displaced intracapsular fractures in the elderly is associated with a reduced re-operation rate but at the expense of a marginally increased mortality.
We assessed 882 patients presenting with a proximal femoral fracture by a new mobility score and by a mental test score, to determine which was of the most value in forecasting mortality at one year. Both scores gave a highly significant prediction, but the mobility score had a greater predictive value and is easier to perform.
We studied prospectively a consecutive series of 765 patients with proximal femoral fractures to determine if the time interval between injury and surgery influenced the outcome. Patients in whom surgery had been delayed for medical reasons were excluded. We divided the patients into four groups depending on the delay to surgery. Analysis of pre- and postoperative characteristics showed the groups to be similar. Mortality in the four groups was not significantly different but morbidity was increased by delay, particularly with regard to the incidence of pressure sores.