While computed tomography (CT) provides an accurate measure of osteolysis volume, it would be advantageous in general clinical practice if plain radiographs could be used to monitor osteolysis. This study determined the ability of plain radiographs to detect the presence of and determine the progression in size of osteolytic lesions around cementless acetabular components. Nineteen acetabular components were diagnosed with osteolysis using a high-resolution multi-slice CT scanner with metal artefact suppression. Mean duration since arthroplasty was 14 years (range 10–15 years) at initial CT. Repeat CT scans were undertaken over a five year period to determine osteolysis progression. On anteroposterior pelvis (AP) radiographs and oblique radiographs of the acetabulum seen on the rolled lateral hip view, which were taken at the same time as the CT scans, area of osteolysis was measured manually correcting for magnification. Osteolysis was detected on the AP radiographs in 8 of 19 hips (42%), on the oblique radiographs in 6 of 19 hips (32%) and on the combined AP and oblique radiographs in 8 of 19 hips (42%). Throughout the study period, osteolysis was detected on 31 of 76 AP radiographs (41%) and 22 of 75 oblique radiographs (29%). Osteolysis was more likely to be detected on plain radiographs if the lesion volume was greater than 10cm3 in size (p=0.005). On CT, osteolysis progressed by more than 1cm3/yr in 10 of 19 hips (55%). In these ten hips, osteolysis progression was detected on AP radiographs in six hips and on oblique radiographs in three hips. No correlation was found between osteolysis progression measured by CT and that measured on AP (r2=0.16, p=0.37) or oblique (r2=0.37, p=0.15) or AP and oblique radiographs (r2=0.34, p=0.17). Plain radiographs are poor in monitoring progression in size of periacetabular osteolytic lesions. Plain radiographs may detect lesions more than 10cm3 in size, but are unreliable.
Computed tomography (CT) provides a sensitive and accurate measure of periacetabular osteolytic lesion volume, however, there may remain a role for plain radiographs in monitoring osteolysis. This study aimed to compare CT and plain radiographs for determining the progression in size of osteolytic lesions around cementless acetabular components. A high-resolution multi-slice CT scanner with metal artefact suppression was used to determine the volume and progression of osteolysis around 19 cementless Harris Galante-1 and PCA acetabular components. The mean duration since arthroplasty was 14 years (range 10–15 years) at initial CT. Repeat scans of the hip were undertaken over a five year period to determine the progression in size of osteolytic lesions over time. A second blinded observer manually measured the area of osteolytic lesions off anteroposterior pelvis radiographs and oblique radiographs of the acetabulum that were taken at the same time as the CT scan. All 19 hips had CT detected osteolysis. Osteolysis was detected on one or both of the anteroposterior pelvis or oblique radiographs from at least one time point in eight of 19 hips (42%). Osteolysis was detected on 31 of 76 anteroposterior pelvis radiographs (41%) and on 22 of 75 oblique radiographs (29%) (p=0.140). Osteolysis was more likely to be detected on plain radiographs if the lesion volume was greater than 10cm3 in size compared to those 5–10cm3 and less than 5cm3 in size (p=0.009). In 10 of 19 hips (55%), CT determined that osteolytic lesions progressed in size by more than 1cm3/yr. The mean volume of osteolysis progression was 3.2cm3/yr (range 1.1–7.5cm3/yr). Progression in size of osteolytic lesions was significantly associated with hips with larger osteolytic lesions at the initial CT (p=0.0004). Radiographic measurements detected progression of osteolytic lesions in 5 of the 10 hips (50%) that progressed. No correlation was found between progression in size of osteolytic lesions as measured by CT and progression in size of osteolytic lesions as measured off the anteroposterior pelvis (r2 = 0.16, p=0.37), oblique (r2=0.37, p=0.15) and combined anteroposterior pelvis and oblique radiographs (r2=0.34, p=0.17). Periacetabular osteolytic lesions are more likely to be detected on plain radiographs if they are more than 10cm3 in size. Plain radiographs may therefore provide some monitoring value as lesions more than 10cm3 are more likely to be progressive. However, plain radiographs should not be relied upon to monitor the progression of these lesions.
In vitro studies recommend concentric placement of the acetabular component. There are however no in vitro studies on acetabular component positioning.
There was no difference in mean dose of propofol used in either group, 15mg/kg/hr (