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The Bone & Joint Journal
Vol. 106-B, Issue 7 | Pages 744 - 750
1 Jul 2024
Saeed A Bradley CS Verma Y Kelley SP

Aims. Radiological residual acetabular dysplasia (RAD) has been reported in up to 30% of children who had successful brace treatment of infant developmental dysplasia of the hip (DDH). Predicting those who will resolve and those who may need corrective surgery is important to optimize follow-up protocols. In this study we have aimed to identify the prevalence and predictors of RAD at two years and five years post-bracing. Methods. This was a single-centre, prospective longitudinal cohort study of infants with DDH managed using a published, standardized Pavlik harness protocol between January 2012 and December 2016. RAD was measured at two years’ mean follow-up using acetabular index-lateral edge (AI-L) and acetabular index-sourcil (AI-S), and at five years using AI-L, AI-S, centre-edge angle (CEA), and acetabular depth ratio (ADR). Each hip was classified based on published normative values for normal, borderline (1 to 2 standard deviations (SDs)), or dysplastic (> 2 SDs) based on sex, age, and laterality. Results. Of 202 infants who completed the protocol, 181 (90%) had two and five years’ follow-up radiographs. At two years, in 304 initially pathological hips, the prevalence of RAD (dysplastic) was 10% and RAD (borderline) was 30%. At five years, RAD (dysplastic) decreased to 1% to 3% and RAD (borderline) decreased to < 1% to 2%. On logistic regression, no variables were predictive of RAD at two years. Only AI-L at two years was predictive of RAD at five years (p < 0.001). If both hips were normal at two years’ follow-up (n = 96), all remained normal at five years. In those with bilateral borderline hips at two years (n = 21), only two were borderline at five years, none were dysplastic. In those with either borderline-dysplastic or bilateral dysplasia at two years (n = 26), three (12%) were dysplastic at five years. Conclusion. The majority of patients with RAD at two years post-brace treatment, spontaneously resolved by five years. Therefore, children with normal radiographs at two years post-brace treatment can be discharged. Targeted follow-up for those with abnormal AI-L at two years will identify the few who may benefit from surgical correction at five years’ follow-up. Cite this article: Bone Joint J 2024;106-B(7):744–750


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_II | Pages 129 - 129
1 Feb 2004
Street J Phillips M O’Byrne J McCormack D
Full Access

Management of symptomatic residual acetabular dysplasia in adolescence and early adulthood remains a major therapeutic challenge. At our unit the two senior authors review all patients preoperatively and simultaneously perform each procedure. In the four years from 1998 forty-three Bernese osteotomies were performed in 40 patients with residual acetabular dysplasia. The mean average age at surgery was 21 years (range 12 – 43 years) and there were 34 female patients. The indication for surgery was symptomatic hip dysplasia (all idiopathic but for one male with a history of slipped capital femoral epiphysis) presenting with pain and restricted ambulation. 4 patients had previous surgery on the affected hip (2 Salter’s osteotomy, one Shelf procedure and one proximal femoral osteotomy). 27.5% of patients had symptomatic bilateral disease. 42% of patients had Severin class IV or V dysplasia at presentation. 100% of patients had preservation of the hip joint at last follow-up evaluation (mean 2.4 years), with excellent results in 82%, an average post-operative Harris hip score of 96, and an average d’Aubigne hip score of 16.1. The mean post-operative improvements in radiographic measures were as follows: Anterior centre edge angle +19.4°, Lateral centre angle +25.8°, Acetabular Index – 10.7°. Head to Ischial distance – 7.3mm. Surgical operative time decreased from 128 minutes to 43 minutes from the first to the most recent case. Average blood loss has reduced from 1850mls to 420mls over the four years experience. Predonation of 2 units of blood requested from all patients with baseline hemoglobin of > 12g/dl. When combined with intraoperative cell salvage the need for transfusion of homologous blood has been eliminated. All complications occurred in the first 9 patients: (one major – iliac vein injury requiring no further treatment; four moderate – lateral cutaneous nerve injuries; four minor – asymptomatic heterotopic ossification). Our experience confirms that the Ganz peri-acetabular osteotomy is an efficacious procedure for the treatment of the residually dysplastic hip, providing excellent clinical results, where early intervention is the key to improved outcome. It is a technically demanding procedure with a significant early learning curve and we believe that a two-surgeon approach is invaluable to the management of these difficult cases


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_III | Pages 271 - 271
1 Mar 2003
Milickovic S Vukasinovic Z
Full Access

Treatment of residual acetabular dysplasia is still controversial regarding the timing of Surgery, and the type of surgical procedur. Material and Methods: We analyzed 70 patients (83 hips) operated between 1980–1988 year, in which Salter innominate osteotomy was performed in the treatment of residual acetabular dysplasia in DDH. Patients were divided in two different age groups: from 2–4 (53 hips) and 4–6 (30 hips) years. The average follow up was 7 years (from 2 to 10 years). Acetabular remodeling was radiographically assessed by measuring of the Acetabular Index (AI) at the beginning and after the 5 years of age subsequently by measuring the CE angle of Wiberg. All preoperative hips were dysplastic according to Tonnis (+2SD) criteria. Results were statistically analyzed by using the Student’s T test, and One Way Repeated Measures ANOVA, with the correction for the different age groups. Results: We found that there were no statistically significant differences in AI and CE angle between these two age groups and between these groups and normal values. Conclusion: We recommend Salter innominate osteotomy as a procedure of choice in the treatment of acetabular dysplasia in DDH, provided the patient is younger than 6 years of age


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_III | Pages 204 - 205
1 Mar 2003
Pitto R Schramm M Hohmann D
Full Access

The purpose of this study was to evaluate the long-term clinical and radiological results of patients with hip dysplasia who underwent spherical acetabular osteotomy. The surgical technique used was that described by Wagner.

The first 26 unilateral spherical osteotomies performed by one surgeon at one institution were reviewed at a minimum clinical follow-up of 20 years (median 23.9, maximum 29 years). One patient had died 5 years after the index operation unrelated to the procedure. Three patients (3 hips, 11 %) could not be traced. Preoperative and follow-up radiographic measurements included lateral and anterior centre-edge angle, acetabular index angle, and acetabulum-head index of Heyman and Herndon. Antero-posterior radiographs of the pelvis were evaluated for the presence of joint congruency, joint space narrowing, increased sclerosis of the subchondral bone, and bone cysts.

Osteotomy improved the mean lateral centre-edge angle from −20 to +130, and the acetabular head index from 52% to 72%. The mean postoperative anterior centre-edge angle of Lequesne and de Seze was 23 (range: −10 to 62). Seven of 22 hips (32%) needed conversion to total hip replacement. The average Harris hip score at latest follow-up of the remaining 15 hips was rated 86 points (range: 50 to 100 points). Overall, 11 of the 15 hips were clinically rated good or excellent. On latest follow-up severity of osteoarthritis was unchanged in 13 of 15 hips. Only 3 of 9 hips requiring conversion to total hip replacement or showing progressive osteoarthritis were rated congruent after the index operation. On the other hand, 10 of 13 hips not requiring conversion to total hip replacement or progressive osteoarthritis were congruent. The 20-year-follow-up Kaplan-Meier survival estimates based on conversion to total hip replacement as an end point was 86.4%. (95% confidence interval: 63.4% to 95.4%). The 25-year-follow-up survivorship was 65.1 % (95% confidence interval: 35.6% to 83.7%).

The long-term results of the spherical osteotomy are satisfactory from the standpoint of both improvement in clinical condition and the radiological appearance of the joint. The Wagner spherical osteotomy had prevented progression of degenerative changes in 13 out of 22 hips (59%) after a median 23.9 year follow-up. Congruency of the joint seems to be a major factor predicting long-term outcome.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 21 - 21
1 Sep 2012
Pospischill R Weninger J Pokorny A Altenhuber J Ganger R Grill F
Full Access

Background. Several risk factors for the development of osteonecrosis following treatment of developmental dislocated hip have been reported. The need for further research with a large-enough sample size including statistical adjustment of confounders was demanded. The purpose of the present study was to find reliable predictors of osteonecrosis in patients managed for developmental dislocation of the hip. Methods. A retrospective cohort study of children, who have been hospitalized at our department between January 1998 and February 2007 with a developmental dislocation of the hip, was completed. Sixty-four patients satisfied the criteria for inclusion. Three groups according to age and treatment were identified. Group A and B included patients treated with closed or open reductions aged less than twelve months. Patients of group C were past walking age at the time of reduction and were treated by open reduction combined with concomitant pelvic and femoral osteotomies. The average duration of follow-up for all patients was 6.8 years. Logistic regression analysis was conducted to identify predictors for the development of osteonecrosis. Results. The overall rate of osteonecrosis in group A and B was 27.4% compared to 88.2% in patients of group C. After pooling of all data, no protective effect of the ossific nucleus of the femoral head on the development of osteonecrosis was found (p = 0.14). Additionally, an increase of surgical procedures in children of group C could not be demonstrated (p = 0.17). By using logistic regression analysis the type of reduction and secondary reconstructive procedure due to residual acetabular dysplasia could be identified as predictors for the development of osteonecrosis. Conclusions. Open reduction combined with concomitant osteotomies and secondary reconstructive interventions due to residual acetabular dysplasia increase the risk for osteonecrosis in the treatment of the developmental dislocated hip. Therefore, we advocate early reduction of the dislocated hip in the first year of life to avoid the need for concomitant osteotomies combined with open reduction. Level of Evidence. Prognostic study, level II-1 (retrospective study)


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 56 - 56
1 Mar 2006
Street J Lenehan B Phillips M O’Byrne J McCormack D
Full Access

Management of symptomatic residual acetabular dysplasia in adolescence and early adulthood remains a major therapeutic challenge. At our unit the two senior authors review all patients preoperatively and simultaneously perform each procedure. In the four years from 1998 forty-three Bernese osteotomies were performed in 40 patients with residual acetabular dysplasia. The mean average age at surgery was 21 years (range 12 – 43 years) and there were 34 female patients. The indication for surgery was symptomatic hip dysplasia (all idiopathic but for one male with a history of slipped capital femoral epiphysis) presenting with pain and restricted ambulation. 4 patients had previous surgery on the affected hip (2 Salter’s osteotomy, one Shelf procedure and one proximal femoral osteotomy). 27.5% of patients had symptomatic bilateral disease. 42% of patients had Severin class IV or V dysplasia at presentation. 100% of patients had preservation of the hip joint at last follow-up evaluation (mean 2.4 years), with excellent results in 82%, an average post-operative Harris hip score of 96, and an average d’Aubigne hip score of 16.1. The mean post-operative improvements in radiographic measures were as follows: Anterior centre edge angle +19.4°, Lateral centre angle +25.8°, Acetabular Index – 10.7°. Head to Ischial distance – 7.3mm. Surgical operative time decreased from 128 minutes to 43 minutes from the first to the most recent case. Average blood loss has reduced from 1850mls to 420mls over the four years experience. Predonation of 2 units of blood requested from all patients with baseline hemoglobin of > 12g/dl. When combined with intraopera-tive cell salvage the need for transfusion of homologous blood has been eliminated. All complications occurred in the first 9 patients: (one major – iliac vein injury requiring no further treatment; four moderate – lateral cutaneous nerve injuries; four minor – asymptomatic heterotopic ossification). Our experience confirms that the Ganz periacetabular osteotomy is an efficacious procedure for the treatment of the residually dysplastic hip, providing excellent clinical results, where early intervention is the key to improved outcome. It is a technically demanding procedure with a significant early learning curve and we believe that a two


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_9 | Pages 7 - 7
1 Aug 2015
Carsi M Clarke N
Full Access

This retrospective matched cohort study tested the hypothesis that an incomplete periacetabular acetabuloplasty, as an added step to delayed open reduction, diminishes the risk of developing acetabular dysplasia. 29 hips from 23 patients with idiopathic DDH that underwent intentionally delayed open reduction and acetabuloplasty at our institution from 2003 to 2010 were matched for age at presentation and bilaterality to historic controls. These were 29 hips from 26 patients, treated with open reduction alone from 1989 to 2003. Residual dysplasia treated with pelvic osteotomy, AVN grade II-IV, and rate of re-intervention were the outcome measures. The mean ages at diagnosis and at surgery were 8.62 weeks and 12.97 months, respectively. At latest follow-up, 27 hips in the acetabuloplasty group and 22 in the open reduction alone group had satisfactory radiographic outcome (Severin class Ia, Ib or II) (p=0.16). 18 of the 58 hips (31.0%) had AVN, 7 (24.14%) in the case group and 11(37.93%) in the control group. Further surgery was required in 15 of the 29 hips in the open reduction alone group. These included 2 revision of open reductions, 5 pelvic osteotomies, 3 varus derotation osteotomies, and 5 apo or epiphysiodesis whilst only one patient in the acetabuloplasty group required a medial screw epiphysiodesis for late lateral growth arrest. There is a positive association between the need for further surgery and open reductions alone: the odds ratio is 14.00 and the 95% confidence interval (1.97, 99.63), p=0.0017. The five hips in the open reduction alone group that required a pelvic osteotomy were intervened at an average of 31.45 (±9.07) months. The addition of an incomplete periacetabular periacetabuloplasty to all hips undergoing open reduction eliminated residual acetabular dysplasia in this cohort whilst it does not appear to have deleterious effects, as evidenced by the similar Severin and McKay scores


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_II | Pages 103 - 103
1 Feb 2003
O’Hara JN Munjal S
Full Access

In the period 1991 to 1993, twenty-five patients had Tonnis Triple Pelvis Osteotomy (TPO) performed. The presenting condition was primary or residual acetabular dysplasia. The age range was 24 to 54. Fifteen operations were on the left and two patients had bilateral operations at intervals of more than one year. The anterior approach (Salter incision) was limited to an internal dissection, with the most limited possible abductor elevation of 2cm at the level of the iliac osteotomy. An Orthofix leg-lengthener was used intraoperatively to manoeuvre the central acetabular fragment, to accurately correct the presenting deformity as determined by CT scans. Two or three 6. 5mm screws were used to fix the osteotomy. No immobilisation was used. Mean blood loss was 580mis (range 375–1050mis). All patients presented with pain, and only two patients had (mild) pain at review. The adult acetabular index was corrected from mean 31 deg to mean 4deg (max 1 Odeg). The CEA was corrected from mean 8 deg to 20–35 (mean 29) degrees. There was one temporary sciatic neuropraxia in the first patient. One patient has been converted to a resurfacing. Harris Hip Scores (HHS) have been measured yearly from three years post-op. Presenting HHS was mean 58 (range 44–72). At most recent follow-up it was mean 91 (range 79–1 00). Only two patients had HHS < 85. These patients had only 50% joint space at presentation. There was no reduction in HHS with longer follow-up. The operation shows durable and promising results in the medium-term, consistent with other series reported in Europe. The authors recommend that this type of operation be performed before any joint space narrowing develops, so that irretrievable deterioration occurs


The Bone & Joint Journal
Vol. 105-B, Issue 2 | Pages 140 - 147
1 Feb 2023
Fu Z Zhang Z Deng S Yang J Li B Zhang H Liu J

Aims

Eccentric reductions may become concentric through femoral head ‘docking’ (FHD) following closed reduction (CR) for developmental dysplasia of the hip (DDH). However, changes regarding position and morphology through FHD are not well understood. We aimed to assess these changes using serial MRI.

Methods

We reviewed 103 patients with DDH successfully treated by CR and spica casting in a single institution between January 2016 and December 2020. MRI was routinely performed immediately after CR and at the end of each cast. Using MRI, we described the labrum-acetabular cartilage complex (LACC) morphology, and measured the femoral head to triradiate cartilage distance (FTD) on the midcoronal section. A total of 13 hips with initial complete reduction (i.e. FTD < 1 mm) and ten hips with incomplete MRI follow-up were excluded. A total of 86 patients (92 hips) with a FTD > 1 mm were included in the analysis.


The Bone & Joint Journal
Vol. 105-B, Issue 8 | Pages 935 - 942
1 Aug 2023
Bradley CS Verma Y Maddock CL Wedge JH Gargan MF Kelley SP

Aims

Brace treatment is the cornerstone of managing developmental dysplasia of the hip (DDH), yet there is a lack of evidence-based treatment protocols, which results in wide variations in practice. To resolve this, we have developed a comprehensive nonoperative treatment protocol conforming to published consensus principles, with well-defined a priori criteria for inclusion and successful treatment.

Methods

This was a single-centre, prospective, longitudinal cohort study of a consecutive series of infants with ultrasound-confirmed DDH who underwent a comprehensive nonoperative brace management protocol in a unified multidisciplinary clinic between January 2012 and December 2016 with five-year follow-up radiographs. The radiological outcomes were acetabular index-lateral edge (AI-L), acetabular index-sourcil (AI-S), centre-edge angle (CEA), acetabular depth ratio (ADR), International Hip Dysplasia Institute (IHDI) grade, and evidence of avascular necrosis (AVN). At five years, each hip was classified as normal (< 1 SD), borderline dysplastic (1 to 2 SDs), or dysplastic (> 2 SDs) based on validated radiological norm-referenced values.


Bone & Joint Open
Vol. 1, Issue 4 | Pages 55 - 63
7 Apr 2020
Terjesen T Horn J

Aims

When the present study was initiated, we changed the treatment for late-detected developmental dislocation of the hip (DDH) from several weeks of skin traction to markedly shorter traction time. The aim of this prospective study was to evaluate this change, with special emphasis on the rate of stable closed reduction according to patient age, the development of the acetabulum, and the outcome at skeletal maturity.

Methods

From 1996 to 2005, 49 children (52 hips) were treated for late-detected DDH. Their mean age was 13.3 months (3 to 33) at reduction. Prereduction skin traction was used for a mean of 11 days (0 to 27). Gentle closed reduction under general anaesthesia was attempted in all the hips. Concurrent pelvic osteotomy was not performed. The hips were evaluated at one, three and five years after reduction, at age eight to ten years, and at skeletal maturity. Mean age at the last follow-up was 15.7 years (13 to 21).


Bone & Joint 360
Vol. 6, Issue 4 | Pages 31 - 34
1 Aug 2017


Bone & Joint 360
Vol. 7, Issue 6 | Pages 36 - 39
1 Dec 2018


Bone & Joint 360
Vol. 6, Issue 6 | Pages 36 - 38
1 Dec 2017


Bone & Joint 360
Vol. 2, Issue 6 | Pages 31 - 33
1 Dec 2013

The December 2013 Children’s orthopaedics Roundup360 looks at: Long term-changes in hip morphology following osteotomy; Arthrogrypotic wrist contractures are surgically amenable; Paediatric femoral lengthening over a nail; Current management of paediatric supracondylar fractures; MRI perfusion index predictive of Perthes’ progression; Abduction bracing effective in residual acetabular deformity; Hurler syndrome in the spotlight; and the Pavlik works for femoral fractures too!


Bone & Joint 360
Vol. 4, Issue 5 | Pages 26 - 28
1 Oct 2015

The October 2015 Children’s orthopaedics Roundup360 looks at: Radiographic follow-up of DDH; When the supracondylar goes wrong; Apophyseal avulsion fractures; The ‘pulled elbow’; Surgical treatment of active or aggressive aneurysmal bone cysts in children; Improving stability in supracondylar fractures; Biological reconstruction may be preferable in children’s osteosarcoma; The paediatric hip fracture


Bone & Joint Research
Vol. 3, Issue 1 | Pages 1 - 6
1 Jan 2014
Yamada K Mihara H Fujii H Hachiya M

Objectives

There are several reports clarifying successful results following open reduction using Ludloff’s medial approach for congenital (CDH) or developmental dislocation of the hip (DDH). This study aimed to reveal the long-term post-operative course until the period of hip-joint maturity after the conventional surgical treatments.

Methods

A long-term follow-up beyond the age of hip-joint maturity was performed for 115 hips in 103 patients who underwent open reduction using Ludloff’s medial approach in our hospital. The mean age at surgery was 8.5 months (2 to 26) and the mean follow-up was 20.3 years (15 to 28). The radiological condition at full growth of the hip joint was evaluated by Severin’s classification.