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The Journal of Bone & Joint Surgery British Volume
Vol. 47-B, Issue 4 | Pages 728 - 738
1 Nov 1965
Devas MB

1. Stress fractures of the femoral neck in twenty-five patients are described. 2. Two distinct radiological types, compression fractures and transverse fractures, are described. A clinical distinction cannot be made in the early stages. 3. The importance of the early differential diagnosis between the two types is emphasised because the transverse stress fracture of the femoral neck will become displaced. 4. The morbidity after a displaced transverse fracture of the femoral neck can be severe


The Journal of Bone & Joint Surgery British Volume
Vol. 43-B, Issue 1 | Pages 87 - 89
1 Feb 1961
Maudsley RH Arden GP

1. Three cases are described of a calf swelling occurring in rheumatoid arthritis. 2. This condition has been described by Baker, though many of his patients had tuberculous infection of the knee. 3. The diagnosis may present difficulty because of the distance of the swelling from its origin in the knee joint. 4. Excision of the cyst is advised when it causes pain, but recurrence is likely if disease of the joint remains active


Bone & Joint Research
Vol. 6, Issue 12 | Pages 640 - 648
1 Dec 2017
Xia B Li Y Zhou J Tian B Feng L

Objectives

Osteoporosis is a chronic disease. The aim of this study was to identify key genes in osteoporosis.

Methods

Microarray data sets GSE56815 and GSE56814, comprising 67 osteoporosis blood samples and 62 control blood samples, were obtained from the Gene Expression Omnibus database. Differentially expressed genes (DEGs) were identified in osteoporosis using Limma package (3.2.1) and Meta-MA packages. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analyses were performed to identify biological functions. Furthermore, the transcriptional regulatory network was established between the top 20 DEGs and transcriptional factors using the UCSC ENCODE Genome Browser. Receiver operating characteristic (ROC) analysis was applied to investigate the diagnostic value of several DEGs.


The Journal of Bone & Joint Surgery British Volume
Vol. 66-B, Issue 4 | Pages 586 - 591
1 Aug 1984
Guiloff R Scadding J Klenerman L

In an attempt to improve the accuracy of diagnosis, 16 patients suffering from Morton's metatarsalgia were investigated clinically and electrophysiologically. The histological findings were related to these observations. The precise aetiology of Morton's metatarsalgia remains obscure, but the findings are compatible with an entrapment syndrome. Nerve conduction studies have a place in the investigation of patients with atypical presentation of pain in the foot. Further refinement of the electrophysiological technique should be possible


The Journal of Bone & Joint Surgery British Volume
Vol. 84-B, Issue 6 | Pages 873 - 877
1 Aug 2002
Lackman RD Khoury LD Esmail A Donthineni-Rao R

Giant-cell tumours of the sacrum are difficult to treat. Surgery carries a high risk of morbidity, local recurrence and mortality. Radiation is effective in some patients, but has a risk of malignant change. We evaluated the effectiveness of serial arterial embolisation as an alternative to surgery. Five patients with giant-cell tumours of the sacrum which had been primarily treated by serial embolisation were retrospectively reviewed for changes in the size of the tumour. In four the symptoms resolved with full return of function and arrest in the growth of the tumour. They remained free from growth, recurrence, or metastases at follow-up (4 to 17 years). One patient died from metastatic disease within 18 months of the initial diagnosis


The Journal of Bone & Joint Surgery British Volume
Vol. 59-B, Issue 4 | Pages 485 - 489
1 Nov 1977
Simons G

A radiographic method is described for making the diagnosis of talo-navicular subluxation before ossification of the navicular bone occurs. Seven basic combinations of deformities are thought to occur in the club foot. Radiography before operation enables the surgeon to determine which of these combinations exists in a particular foot, and radiography during operation enables him to determine wheter or not all the existing deformities have been corrected, and therefore whether or not the operation must be extended


The Journal of Bone & Joint Surgery British Volume
Vol. 57-B, Issue 1 | Pages 104 - 105
1 Feb 1975
Sutherland AD

Joint deformity secondary to extensive haemangiomatous involvement of the soft tissues has been well described and is easy to diagnose. If the haemangioma is small, localised and within the belly of a muscle the diagnosis is more difficult. In equinus deformity of obscure aetiology localised calf tenderness may be the only diagnostic sign. Three children with equinus deformity caused by a small haemangioma in the calf muscles were treated by simple excision with satisfactory results


The Journal of Bone & Joint Surgery British Volume
Vol. 50-B, Issue 1 | Pages 116 - 127
1 Feb 1968
Clough JR Price CHG

1. The clinical, radiological, operative and histological features of twelve aneurysmal bone cysts are recorded. 2. Attention is drawn to atypical features, and the problem of diagnosis is discussed. 3. It is recommended that treatment should be complete excision, except where this would interfere with function. 4. Various theories on pathogenesis are considered and favour given to the view that these cysts result from a local change in haemodynamics occurring possibly in a pre-existing lesion


The Journal of Bone & Joint Surgery British Volume
Vol. 40-B, Issue 1 | Pages 47 - 57
1 Feb 1958
Busfield PI

1. Neuroblastoma is a disease that may concern the orthopaedic surgeon closely. 2. Six such cases are reported. 3. Early diagnosis may be difficult, but can be achieved if the condition is suspected and an adequate investigation is carried out on suspicion alone. 4. The prognosis in these patients is still poor, but might be improved by a vigorous combination of surgery, irradiation and chemotherapy. The recent advance in treatment with vitamin B 12 may improve the prognosis substantially


The Journal of Bone & Joint Surgery British Volume
Vol. 35-B, Issue 1 | Pages 57 - 69
1 Feb 1953
Buxton SJD Waugh W

1 . Complications of the Judet arthroplasty are few. 2. The antero-lateral approach provides good access to the joint for insertion of the prosthesis. 3. Details of treatment before and after operation are described and their importance in limiting complications is emphasised. 4. The complications that have been encountered—including dislocation and fracture of the stem—are described and factors in their causation are discussed. 5. Study of the mechanical state of the new joint and the diagnosis of complications are aided by radio-opaque markers in the prosthesis


The Journal of Bone & Joint Surgery British Volume
Vol. 84-B, Issue 5 | Pages 706 - 711
1 Jul 2002
Foukas AF Deshmukh NS Grimer RJ Mangham DC Mangos EG Taylor S

We studied 55 patients with stage-IIB osteosarcoma around the knee with respect to the expression of matrix metalloproteinase (MMP)-9 in the surviving tumour cells in surgical resection specimens. They were followed up for a minimum of 2.5 years. Factors significantly associated with poor overall survival were a high serum level of alkaline phosphatase at diagnosis and tumour cells expressing MMP-9 in the resection specimens. The only factor strongly associated with disease-free survival was the immunohistochemical status of tumour cells for MMP-9 in the resection specimens. The percentage of necrosis after chemotherapy failed marginally to reach statistical significance. On Cox regression analysis only MMP-9 remained significant for overall and disease-free survival


The Journal of Bone & Joint Surgery British Volume
Vol. 72-B, Issue 1 | Pages 94 - 97
1 Jan 1990
Paterson M Hoffman E Roux P

We reviewed the records of 1,156 patients treated for acute staphylococcal osteitis or septic arthritis over a 12-year period; 38 had been critically ill with evidence of multiple-organ involvement and 30 (79%) had features of the toxic shock syndrome. The mortality rate of these 38 patients was 13% and the long-term orthopaedic complication rate was 39%. The diagnosis and management of patients with osteitis or septic arthritis, disseminated staphylococcal disease, and the toxic shock syndrome is discussed


The Journal of Bone & Joint Surgery British Volume
Vol. 75-B, Issue 2 | Pages 233 - 239
1 Mar 1993
Hoffman E Crosier J Cremin B

We compared the usefulness of radiography, CT and MRI in 25 children with spinal tuberculosis. Radiography provided most of the information necessary for diagnosis and treatment. Axial CT was the most accurate method for visualising the posterior bony elements. Sagittal MRI best showed the severity and content of extradural compression and helped to differentiate between an abscess and fibrous tissue. The main value of CT and MRI is in the preoperative evaluation of the small proportion of patients who require surgical treatment for paraplegia


The Journal of Bone & Joint Surgery British Volume
Vol. 70-B, Issue 5 | Pages 807 - 811
1 Nov 1988
Maurice H Crone M Watt I

We reviewed 53 cases of synovial chondromatosis and compared their clinical, radiological and pathological features. A radiological diagnosis is possible with increasing frequency as the disease progresses; in the early phase arthrography is helpful. Radiologically the disease may be classified as either extra-articular, or intra-articular; the intra-articular variety may be localised or generalised. Recurrence after operation was seen in 11.5% and was much the same after either synovectomy or simple removal of loose bodies. A protocol for treatment is proposed


The Journal of Bone & Joint Surgery British Volume
Vol. 70-B, Issue 5 | Pages 798 - 801
1 Nov 1988
McAuliffe T Pangayatselvan T Bayley I

We have reviewed 36 patients who had recurrent anterior dislocation of the shoulder after a previous anterior repair and analysed the various causes of failure. It was found that failure could have been avoided in virtually all of the patients by correct pre-operative diagnosis, selection of the appropriate operation and its proper execution. The further management of these patients is described and suggestions are made as to means of reducing the incidence of failure after primary operation


The Bone & Joint Journal
Vol. 100-B, Issue 6 | Pages 687 - 692
1 Jun 2018
McCormack DJ Gulati A Mangwani J

Our aim in this paper was to investigate the guidelines and laws governing informed consent in the English-speaking world. We noted a recent divergence from medical paternalism within the United Kingdom, highlighted by the Montgomery v Lanarkshire Health Board ruling of 2015. We investigated the situation in the United Kingdom, Australia, New Zealand, Canada, and the United States of America. We read the national guidance regarding obtaining consent for surgical intervention for each country. We used the references from this guidance to identify the laws that helped inform the guidance, and reviewed the court documents for each case.

There has been a trend towards a more patient-focused approach in consent in each country. Surgeons should be aware of the guidance and legal cases so that they can inform patients fully, and prevent legal problems if outdated practices are followed.

Cite this article: Bone Joint J 2018;100-B:687–92.


The Bone & Joint Journal
Vol. 100-B, Issue 6 | Pages 755 - 760
1 Jun 2018
Lou T Hamushan M Li H Wang C Chai Y Han P

Aims

The aim of this study was to describe the technique of distraction osteogenesis followed by arthrodesis using internal fixation to manage complex conditions of the ankle, and to present the results of this technique.

Patients and Methods

Between 2008 and 2014, distraction osteogenesis followed by arthrodesis using internal fixation was performed in 12 patients with complex conditions of the ankle due to trauma or infection. There were eight men and four women: their mean age was 35 years (23 to 51) at the time of surgery. Bone healing and functional recovery were evaluated according to the criteria described by Paley. Function was assessed using the ankle-hindfoot scale of the American Orthopedic Foot and Ankle Society (AOFAS).


The Journal of Bone & Joint Surgery British Volume
Vol. 84-B, Issue 4 | Pages 530 - 534
1 May 2002
Bhojraj S Nene A

We have reviewed, retrospectively, 66 adult patients who were treated for lumbar or lumbosacral tuberculosis. A total of 45 had a paravertebral or epidural abscess, 24 had clinical instability and 18 presented with a radiculopathy, of which six also had a motor deficit. The diagnosis was usually made on clinical and radiological grounds and they were followed up until there were clinical and radiological signs of full recovery. Conservative treatment with antituberculous drugs was successful in 55 patients (83%). None had persistent instability, radiculopathy or neurological compromise. We feel that tuberculous spondylodiscitis, especially in the lumbar spine, can usually be satisfactorily managed conservatively and that there are few indications for surgical treatment


The Journal of Bone & Joint Surgery British Volume
Vol. 69-B, Issue 3 | Pages 453 - 456
1 May 1987
van den Oever M Merrick M Scott J

In 66 patients with back pain and suspected spondylolysis, the results of bone scintigraphy have been correlated with operative findings and clinical follow-up. Although bone scintigraphy is of little value for primary diagnosis, it helps to distinguish between those patients with established non-union of the defect, and those in whom healing is still progressing and who may benefit from immobilisation. We also found that increased uptake on the contralateral side to a unilateral spondylolysis is suggestive of impending fracture


The Journal of Bone & Joint Surgery British Volume
Vol. 69-B, Issue 1 | Pages 41 - 44
1 Jan 1987
de Jonge-Bok J Macfarlane J

This report details seven patients who had an arthropathy at presentation of their haemochromatosis. The spectrum ranged from arthralgia and normal radiographs to classic polyarthritis and the typical radiological triad of joint-space narrowing, sclerosis and cysts. Some atypical presentations are highlighted. An early diagnosis of haemochromatosis requires clinical suspicion; support can be obtained from serum iron studies, particularly saturation of iron-binding capacity and ferritin, and from biopsy of liver and/or synovium