Free radicals, such as reactive oxygen species (ROS) which are released abruptly after deflation of an ischaemic tourniquet, cause reperfusion injuries. Ischaemic precondition (IPC), however, can reduce the injury. In clinical practice, the sequential application and release of tourniquets is often used in bilateral
The appearance of the ‘grand-piano sign’ on the anterior resected surface of the femur has been considered to be a marker for correct femoral rotational alignment during
The results of
PCL retaining fixed-bearing
The results of
Objectives. Because posterior cruciate ligament (PCL) resection makes flexion
gaps wider in
We carried out a prospective randomised study to evaluate the blood loss in 60 patients having a
Between 1992 and 1994 we performed a prospective study of the effect of
We carried out three
We report the long-term results of the management
of neglected chronically infected
We performed a CT-based computer simulation study
to determine how the relationship between any inbuilt posterior
slope in the proximal tibial osteotomy and cutting jig rotational
orientation errors affect tibial component alignment in total knee
replacement. Four different posterior slopes (3°, 5°, 7° and 10°),
each with a rotational error of 5°, 10°, 15°, 20°, 25° or 30°, were
simulated. Tibial cutting block malalignment of 20° of external
rotation can produce varus malalignment of 2.4° and 3.5° with a
7° and a 10° sloped cutting jig, respectively. Care must be taken in
orientating the cutting jig in the sagittal plane when making a
posterior sloped proximal tibial osteotomy in
Intra-operative, peri-articular injection of
local anaesthesia is an increasingly popular way of controlling
pain following
In posterior stabilised total knee replacement
(TKR) a larger femoral component is sometimes selected to manage the
increased flexion gap caused by resection of the posterior cruciate
ligament. However, concerns remain regarding the adverse effect
of the increased anteroposterior dimensions of the femoral component
on the patellofemoral (PF) joint. Meanwhile, the gender-specific
femoral component has a narrower and thinner anterior flange and
is expected to reduce the PF contact force. PF contact forces were
measured at 90°, 120°, 130° and 140° of flexion using the NexGen
Legacy Posterior Stabilized (LPS)-Flex Fixed Bearing Knee system
using Standard, Upsized and Gender femoral components during
We undertook a prospective, randomised study in order to evaluate the efficacy of clamping the drains after intra-articular injection of saline with 1:500 000 adrenaline compared with post-operative blood salvage in reducing blood loss in 212
We investigated the outcome of deep-vein thrombosis (DVT) in the calf after
We previously compared the component alignment in
We analysed the serum C-reactive protein level, synovial fluid obtained by joint aspiration and five synovial biopsies from 145 knee replacements prior to revision to assess the value of these parameters in diagnosing late peri-prosthetic infection. Five further synovial biopsies were used for histological analysis. Samples were also obtained during the revision and incubated and analysed in an identical manner for 14 days. A total of 40
We studied the influence of soft-tissue releases and soft-tissue balance on the outcome of 526
As part of the national initiative to reduce
waiting times for joint replacement surgery in Wales, the Cardiff
and Vale NHS Trust referred 224 patients to the NHS Treatment Centre
in Weston-Super-Mare for
Component malalignment can be associated with
pain following