Induced membrane technique is a relatively new technique in the reconstruction of large bone defects. It involves the implantation of polymethylmethacrylate (PMMA) cement in the bone defects to induce the formation of membranes after radical debridement and reconstruction of bone defects using an autologous cancellous bone graft in a span of four to eight weeks. The purpose of this study was to explore the clinical outcomes of the induced membrane technique for the treatment of post-traumatic osteomyelitis in 32 patients. A total of 32 cases of post-traumatic osteomyelitis were admitted to our department between August 2011 and October 2012. This retrospective study included 22 men and ten women, with a mean age of 40 years (19 to 70). Within this group there were 20 tibias and 12 femurs with a mean defect of 5 cm (1.5 to 12.5). Antibiotic-loaded PMMA cement was inserted into the defects after radical debridement. After approximately eight weeks, the defects were implanted with bone graft.Objectives
Methods
The use of autograft bone is the best option
when undertaking a procedure that requires bone graft because it
is osteogenic, osteoconductive and osseo-inductive. Pain, morbidity
and complications associated with harvesting iliac or non-iliac
sites occur in between 6% and 30% of cases. An alternative source
of graft with possibly a lower morbidity is the intramedullary canal.
In this study, 28 patients undergoing 30 arthrodesis procedures
on the hindfoot had a mean of 48 cm3 (43 to 50) of bone
harvested locally from the hindfoot or the tibial shaft by antegrade or
retrograde reaming. No patient sustained a fracture of the calcaneum,
talus or tibia. There was no morbidity except for one complication
when the reamer breached the medial tibial cortex. This healed uneventfully. This method of using the reamer–irrigator–aspirator system is
an extension of the standard technique of intramedullary reaming
of the lower limb: it produces good-quality bone graft with viable
growth factors consistent with that of the iliac crest, and donor
site morbidity is low. This is an efficient method of obtaining
autologous bone for use in arthrodesis of the ankle or hindfoot.