The medial-stabilised (MS) knee implant, characterised by a spherical medial condyle on the femoral component and a medially congruent tibial bearing, was developed to improve knee kinematics and stability relative to performance obtained in posterior-stabilised (PS) and cruciate-retaining (CR) designs. We aimed to compare in vivo six-degree-of-freedom (6-DOF) kinematics during overground walking for these three knee designs. Seventy-five patients (42 males, 33 females, age 68.4±6.6 years) listed for total knee arthroplasty (TKA) surgery were recruited to this study, which was approved by the relevant Human Research Ethics committees. Each patient was randomly- assigned a PS, CR or MS knee (Medacta International AB, Switzerland) resulting in three groups of 23, 26 and 26 patients, respectively. Patients visited the Biomotion Laboratory at the University of Melbourne 6±1.1 months after surgery, where they walked overground at their self-selected speed. A custom Mobile Biplane X-ray (MoBiX) imaging system tracked and imaged the implanted knee at 200 Hz. The MoBiX system measures 6-DOF tibiofemoral kinematics of TKA knees during overground gait with maximum RMS errors of 0.65° and 0.33 mm for rotations and translations, respectively.INTRODUCTION
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