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The Journal of Bone & Joint Surgery British Volume
Vol. 90-B, Issue 12 | Pages 1597 - 1601
1 Dec 2008
Thompson NW Kapoor A Thomas J Hayton MJ

We describe the use of a vascularised periosteal patch onlay graft based on the 1,2 intercompartmental supraretinacular artery in the management of 11 patients (ten men, one woman) with chronic nonunion involving the proximal third of the scaphoid. The mean age of the patients was 31 years (21 to 45) with the dominant hand affected in eight. Six of the patients were smokers and three had undergone previous surgery to the scaphoid. All of the proximal fragments were avascular. The presence of union was assessed using longitudinal axis CT.

Only three patients progressed to union of the scaphoid and four required a salvage operation for a symptomatic nonunion. The remaining four patients with a persistent nonunion are asymptomatic with low pain scores, good grip strength and a functional range of wrist movement.

Although this technique has potential technical advantages over vascularised pedicled bone grafting, the rate of union has been disappointing and we do not recommend it as a method of treatment.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 540 - 540
1 Aug 2008
O’Flaherty MT Thompson NW Ellis PK Barr RJ
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Introduction: Fractures of the femoral neck are common in elderly patients. Malignancy increases in incidence with increasing age. Therefore, it is inevitable that a proportion of patients with a history of malignancy will suffer a fracture of the femoral neck.

Our aim was to quantify the proportion of patients admitted with a femoral neck fracture and a co-existent history of malignancy, and determine if full-length femoral radiographs are beneficial in preoperative screening of distal metastatic disease.

Methods: 133 patients (47 males, 86 females) were admitted with a femoral neck fracture and co-existent history of malignant disease from January 2004 to 2006. The mean age was 80.1 years (range, 30–96 years). In 114 cases the fracture was traumatic in origin. In 19 cases the fracture was pathological, presenting most commonly with increasing pain.

Primary malignancies included breast (34.6%), large bowel(21.8%), prostatic (18.0%) and bronchogenic carcinomas (6.8%).

There were 73 extracapsular fractures and 60 intracapsular fractures. For the intracapsular fractures 49 cases were treated with hemiarthroplasty, 4 cases by total hip arthroplasty and 7 cases using cannulated screws. For the extracapsular fractures, 59 cases were stabilized using a DHS and 14 cases were managed by intramedullary nailing.

Results: A consultant radiologist reviewed all 133 full-length femoral radiographs (AP and lateral). No patients had evidence of distal pathology visible. No patients were re-admitted with a secondary fracture relating to the development of disease in the distal femur.

Conclusion: Femoral neck fractures do occur in patients with a co-existent history of malignancy. Full-length femoral radiographs of the femur are of no additional benefit for preoperative planning. These patients can be managed similarly to other patients presenting with a femoral neck fracture..


The Journal of Bone & Joint Surgery British Volume
Vol. 89-B, Issue 7 | Pages 915 - 918
1 Jul 2007
Hanratty BM Thompson NW Wilson RK Beverland DE

We have studied the concept of posterior condylar offset and the importance of its restoration on the maximum range of knee flexion after posterior-cruciate-ligament-retaining total knee replacement (TKR). We measured the difference in the posterior condylar offset before and one year after operation in 69 patients who had undergone a primary cruciate-sacrificing mobile bearing TKR by one surgeon using the same implant and a standardised operating technique. In all the patients true pre- and post-operative lateral radiographs had been taken.

The mean pre- and post-operative posterior condylar offset was 25.9 mm (21 to 35) and 26.9 mm (21 to 34), respectively. The mean difference in posterior condylar offset was + 1 mm (−6 to +5). The mean pre-operative knee flexion was 111° (62° to 146°) and at one year postoperatively, it was 107° (51° to 137°).

There was no statistical correlation between the change in knee flexion and the difference in the posterior condylar offset after TKR (Pearson correlation coefficient r = −0.06, p = 0.69).


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_I | Pages 83 - 83
1 Jan 2004
Verzin EJ Mohan B Thompson NW Ruiz A Tohill M Dennison J Beverland D Nixon JR
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We performed a prospective clinical study in order to assess the effectiveness of repair of the short hip rotators, divided in the course of total hip replacement by the posterior approach, by the use of radio-opaque markers.

Fifteen patients, each with a diagnosis of osteoarthritis of the hip, were selected consecutively from a single surgeon’s operating list. Uncemented Duraloc® acetabular components and custom made cemented femoral components were implanted via the posterior approach in all patients.

Following implantation, the capsule and the short rotator tendons were sutured on to tendinous soft tissue around the greater trochanter using No 1 Vicryl. One radio-opaque marker clip was attached to the short rotators and capsule and a second marker was attached to the greater trochanter.

Standard antero-posterior pelvic X-rays were taken at three to five days post-operatively, and at three months following surgery. Significant separation of the radio-opaque markers in fourteen of the fifteen patients was demonstrated on the day three to five X-ray, indicating failure of the repair.

We conclude that this soft tissue repair is unsatisfactory. It may be of value to develop a more effective repair technique, with the overall aim of reducing total hip replacement dislocation, and as such we are currently investigating a soft tissue to bone repair.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_II | Pages 132 - 132
1 Feb 2003
Geddis CJ Thompson NW Watson AM Beverland DE
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Total knee arthroplasty has evolved considerably over the last thirty years. Early implant design achieved the short-term goals of pain relief and mobility, however loosening and polyethylene wear associated with over constraint was problematic. The Low Contact Stress total knee arthroplasty was developed in an attempt to address the problems of loosening and polyethylene wear. The highly congruent interface between the femoral component and the mobile insert minimises stress within the polyethylene and reduces the potential of wear and damage. Furthermore, the mobile bearing phenomenon minimises both torsional and shear stresses at the component bone interface. In our unit the impact of choice is the LCS rotating platform prosthesis, which is inserted with cruciate-sacrifice.

We reviewed 219 patients (272 knees) with an average follow-up of 6 years (5–8 years). In almost all cases the components were inserted with cement fixation. The patella was primarily resurfaced in 20 patients (21 knees). All operations were performed or supervised by the senior author. Female to male ratio was 2:1. Average age at surgery was 68 years (40–86) with osteoarthritis being the commonest primary diagnosis (89%). Postoperative range of motion ranges from 30–130° (average 103°). Average Oxford Knee, American Knee Society Score and Patellar Score was 19 (12–53), 160 (42–199) and 25 (4–30) respectively. Six patients (1.7%) required MUA at six weeks. Two patients (0.6%) required secondary patellar resurfacing. Three patients (0.8%) had revision of their components for persistent pain. At operation all components were noted to be well fixed. Spinout of the rotating platform occurred in one patient (0.3%). This was treated by exchange of the insert.

In conclusion, our early results of the LCS rotating platform prosthesis are encouraging with no cases of component loosening to date. This supports the continued use of the implant.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_I | Pages 60 - 60
1 Jan 2003
Thompson NW Doran EM Ruiz AL Brown JG
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Fracture of the femur in association with total hip arthroplasty is a challenging complication that has been well described. A variety of surgical treatment options have been reported. We present our experience of the Kent hip prosthesis in the management of periprosthetic femoral fractures.

We reviewed all patients (46) who had a Kent hip inserted for a periprosthetic femoral fracture. This group consisted of 16 males and 30 females of average age 73 years (43–96 years) at the time of fracture. Follow up ranged from 2 to 85 months (average, 4 years).

In 26 cases the primary prosthesis was a Charnley stem. Of the remaining cases the primary prostheses were as follows: 6 Austin Moore prostheses, 5 Howse, 4 Custom, 1 Exeter, 1 DHS, 1 Richards and 1 Thompson stem. There were 6 intraoperative fractures. Of the postoperative fractures forty-four were associated with a traumatic event. Time to fracture varied from 3 weeks to 20 years (average, 8 years). Prior to fracture 42 patients were living in their own home and 24 patients were mobile unaided. Twenty patients had pain prior to their fracture. The majority of patients were deemed ASA grade II or III. Thirty fractures were Johanssen type II, 14 type I, and 2 type III.

At the time of surgery, 32 patients had a loose stem and/or cup. Operating time was on average 143 minutes (range, 65–235 minutes) and intraoperative transfusion requirements ranged from 0–7 units of packed red cells (average, 3 units). Duration of hospital stay was on average 23 days (range, 7–77 days). Two patients developed superficial wound infections, six patients dislocated their prosthesis and one patient developed a chronic wound sinus.

In 34 cases fracture union was complete at latest review. Three patients required revision surgery for stem breakage and in 10 cases there was evidence of screw breakage.

At latest review, of the 31 patients that could be contacted 18 are still resident in their own homes. Twenty-six patients require the use of a walking aid (most commonly one stick). Ten patients have ongoing pain in relation to their operated hip.

In conclusion, we feel that the Kent hip prosthesis is a useful surgical option in the one-stage management of periprosthetic femoral fractures.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_I | Pages 58 - 58
1 Jan 2003
Thompson NW Mulgrew AD Cooke A Currie S Nixon JR Beverland DE
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Currently, all details regarding implants are entered into a real time application on the Musgrave Park Hospital site using the Belfast Orthopaedic Information System (BOIS). This is a visual basic client application with data being stored in an SQL server database. This data collection system operates throughout every location within the hospital including the theatre block.

Loss of continuity occurs however when joint replacement takes place in Musgrave Park Hospital and then revision surgery or other procedures are carried out at other locations. The goal therefore of the Northern Ire-land Implant Register is to collect information on all implants performed and their revisions regardless of their location.

The dataset collected is based on the work of the National Joint Replacement Registry. Our system is designed to support and extend that dataset to provide a more comprehensive joint replacement registry database. This means that reports can be provided to individual sites and data entered into the National registry if required at a later stage.

At present every hospital in Northern Ireland is connected to the HPSS network (similar to the HPSSNet in the UK). What has been developed is a web browser based front end, which requires no complex software installation on any client machine. From this web based tool, staff at other locations can access information held at Musgrave Park Hospital, they can select an implant, or record a new implant and then link any revisions or other procedures carried out.

As all of the information is entered directly into the BOIS database, there is no delay in the information being available to all who access the system. This reduces the need for case notes to be transferred to other sites and the need to contact the other site directly regarding the case. The interface also provides a comprehensive reporting capability so that commonly requested standard reports are available for authorized staff to run from their web browser.

We present an overview of how the web interface works in practice and how data is entered into the system.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_I | Pages 57 - 58
1 Jan 2003
Thompson NW Watson AM Geddis CJ O’Brien S Beverland DE
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Rapidly progressive cases of primary idiopathic hip osteoarthrosis are well known and recognised. The prevalence reported in the literature varies from 4–18%. Three types have been identified- type 1 (rapid), type 2 (moderate) and type 3 (delayed) depending on the duration of chondrolysis and the subsequent rate of bone loss per year.

We reviewed the charts of all patients deemed to be RPO type 1 who had underwent hip arthroplasty under the care of the senior author (DEB) over a two-year period in an attempt to identify risk factors, which may have contributed to the rapid progression of their disease. All patients were treated using a custom femoral stem and a spiked Duraloc cementless socket following careful preparation of the acetabulum.

We identified 34 patients (40 hips) with type 1 rapidly progressive osteoarthrosis. Over the same time period 991 patients had underwent primary total hip arthroplasty, giving a prevalence of 4%. Of the 34 patients, 29 were female of average age 70.6 years (range, 51–83 years). All of the bilateral cases (6 patients) were female. Body mass index (BMI) for the female group ranged from 20.6 to 41.1Kg/m2 (average, 28.2kg/m2) whilst that for the males was on average 25.8Kg/m2 (range, 23.4–29.7Kg/m2).

Preoperative erythrocyte sedimentation rate (ESR) was 18mm/hr on average for the female group (range, 2–65mm/hr) and ranged from 3–52mm/hr (average, 20mm/hr) for the male patients. The preoperative Oxford Hip Score averaged 51 points for the female group and 48 points for the male group.

A detailed review of occupational history did not reveal any common occupational hazard. The majority of patients were non-smokers and denied any regular alcohol intake. Twenty-two patients (65%) had a history of hypertension. Twenty-seven patients (79%) had a history of non-steroidal anti-inflammatory use (most common preparation-diclofenac). Twenty-four patients (71%) resided in a rural area.

When compared to a cohort of patients undergoing primary total hip arthroplasty over the same time period, the only statistically significant risk factor identified was female gender.

We conclude, that patients who develop rapidly progressive osteoarthrosis of the hip are difficult to identify due to the absence of specific clinical features. We also outline our experience in the management of these technically challenging cases.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_II | Pages 165 - 165
1 Jul 2002
Thompson NW Wilson DS Beverland DE
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Many factors have been demonstrated to influence the range of knee movement that an individual can achieve.

The purpose of this study was to objectively demonstrate how range of knee movement is affected when the influence of pain is abolished.

Sixty-eight patients with degenerative joint disease presenting for primary total knee arthroplasty were recruited. Using a digital camera, images were taken before and after the induction of anaesthesia with the lower limb in four positions- extension, forced extension, flexion and forced flexion. Camera set up was standard and the range of knee motion was measured from the digital images.

Average arc of motion before anaesthesia was 96° (range, 41°–157°). After induction of anaesthesia, the arc of motion increased to 115° (range, 410–161°). Knee extension improved by an average of 5° (range, 0–15°) and flexion improved by an average of 16° (range, 0–65°).

In conclusion, these results demonstrate that pain has a significant inhibitory effect on the measured range of knee movement before surgical intervention.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_II | Pages 154 - 154
1 Jul 2002
Charlwood P Thompson NW Brown JG Nixon PJR
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Recurrent posterior dislocation is a recognised complication following primary total hip arthroplasty. Incidences of between 0.11% and 4.5% have been reported in the literature.

Component revision is regarded as standard management of recurrent posterior dislocation. However, revision surgery is a major surgical procedure and is often unsuitable for elderly, frail patients.

A congruent, ultra-high molecular weight polyethylene acetabular augment with a stainless steel backing plate has been developed. This can be inserted providing there is no malalignment, wear or loosening of the primary components.

In this study we compared twenty patients who underwent conventional revision surgery to twenty patients who had a PLAD inserted for recurrent posterior dislocation following primary Charnley total hip arthroplasty. Both groups were age and sex-matched and the average number of dislocations prior to surgery was three for each group.

For the PLAD group, the mean operative time, the mean intraoperative blood loss, the time spent in HDU, the transfusion requirements and the duration of hospital stay was significantly less than that for the revision group. Furthermore, there was no significant difference in the Oxford Hip Score recorded preoperatively and at 6 weeks, 6 months, one year and two years following surgery. None of the patients had sustained a further dislocation at latest review.

We conclude that the Posterior Lip Augmentation Device is a safe and effective option in the management of patients with recurrent posterior hip dislocation when there is no evidence of component failure or gross malposition.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_II | Pages 164 - 164
1 Jul 2002
Thompson NW Wilson DS Beverland DE
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Dislocation of the polyethylene-rotating platform is a recognised complication of LCS knee arthroplasty.

We report ten cases of rotating platform dislocation out of 2151 primary total knee arthroplasties (0.5%) performed to date in our unit.

Of the ten cases (3 male: 7 female), six patients had a preoperative valgus deformity, two had a varus deformity and the remaining two patients were in neutral alignment, although the wear was predominantly within the lateral compartment. Two patients also had a previous patellectomy on the side of the platform spinout.

Of the ten cases, six patients were symptomatic as a result of their platform dislocation. The remaining four patients were asymptomatic and mobilising without any difficulty. In these patients, the dislocated platform was diagnosed on x-ray at outpatient review. Time to detection of the platform dislocation ranged from six days to two years.

Three patients required revision of their original insert to a larger, deeper dish insert. Three were managed by open reduction of the original insert. Of the remaining patients, one was managed successfully by closed reduction, one required an arthrodesis and one had the tibial insert cemented to the tibial tray. All patients at latest review have a functional and stable knee joint.

In conclusion, we feel that surgical error was to blame for the majority of our ten cases. Furthermore, we emphasise the importance of producing equal and balanced flexion and extension gaps at the time of knee arthroplasty in order to prevent mobile bearing dislocation. A novel technique for reducing a dislocated rotating platform is also described.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_II | Pages 156 - 156
1 Jul 2002
Thompson NW McAlinden MG Breslin E Crone MD Kernohan WIS Beverland DE
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Periprosthetic fractures are a recognised complication of total knee arthroplasty. They may occur intraoperatively or postoperatively and risk factors have been identified which may predispose an individual to such a complication.

We report seven cases of periprosthetic tibial fractures following LCS total knee arthroplasty, a complication only encountered by the senior author following a change in practice from a cemented implant to a cementless one.

In light of this previously unreported complication in our unit, we have attempted to identify common features within this group of patients, that may have contributed to fracture occurrence.

Statistical analysis revealed a highly significant risk of periprosthetic tibial fracture in those patients with a preoperative neutral or valgus knee. Age, gender and diagnosis did not appear to significantly increase the risk of fracture. All patients displayed evidence of reduced bone mineral density in the lumbar spine and femoral neck regions on dual energy x-ray absorptiometry scanning.

We feel that those patients with a preoperative neutral or valgus knee and local evidence of osteopenia represent a high-risk group, in whom particular care in alignment should be taken. In this group it may also be preferable to have the tibial component inserted with cement fixation.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_II | Pages 157 - 157
1 Jul 2002
Thompson NW Ruiz AL Breslin E Beverland DE
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Isolated patello-femoral osteoarthritis has been reported to occur in approximately 5% of patients with gonarthrosis of the knee. We present the results of the surgical management of this disorder in our unit. Thirty-one patients (33 knees) with symptomatic patello-femoral osteoarthritis and minimal tibio-femoral changes underwent LCS total knee replacement without patellar resurfacing.

Average age was 73 years (range, 58–89 years) with a female to male ratio of 5: 1. Average follow-up was 20 months (range, 12–40 months). All except four patients had grade 3 or 4 patello-femoral osteoarthritis according to the classification by Sperner et al.

Preoperatively, all patients had significant knee pain. Sleep disturbance was reported in 21 patients. All but 10 patients required walking aids. Average range of motion was 108° (range, 80°–125°).

At latest review, 21 knees are pain-free, the remaining 12 knees describing only occasional knee pain. Two patients continue to have night pain. Average range of motion was 104° (range, 700 – 135°). Lateral patellar tilt improved in all but five knees by an average of 7° (range, 10–26°). Patellar congruency improved in all but three knees by an average of 18% (range, 3–63%). None of the patients to date have required revision surgery. We suggest that knee arthroplasty without patellar resurfacing is an effective option in older patients with isolated patello-femoral osteoarthritis.