Anatomical referencing, component positioning, limb alignments and correction of mechanical axes are essential first steps in successful computer assisted navigation. However, apart from basic gap balancing and quantification of ranges of motion, routine navigation technique usually fails to use the full potential of the registered information. Enhanced dynamic assessment using an upgraded navigation system (Brainlab V. 2.2) is now capable of producing enhanced ‘range of motion’ analysis, ‘tracking curves’ and ‘contact point observations’.

‘Range of motion analysis’ was performed simultaneously for both tibio-femoral and patella-femoral joints. Other dynamic information including epicondylar axis motion, valgus and varus alignments, antero-posterior tibio-femoral shifts, as well as flexion and extension gaps were simultaneously stored as a series of ‘tracking curves’ throughout a full range of motion. Simultaneous tracking values for both tibiofemoral and patellofemoral motion was also obtained after performing registration of the prosthetic trochlea. However, there seems to be little point in carrying out such observations without fully assessing joint stability by applying controlled force to the prosthetic joint.

Therefore, in order to fully assess ‘potential envelopes of motion’, observations have been made using a set of standardised simple dynamic tests during insertion and after final positioning of trial components. Also, such tests have been carried out before and after any necessary ligament balancing. Firstly, the lower leg was placed in neutral alignment and the knee put through a flexion-extension cycle. Secondly the test was repeated but with the lower leg being placed into varus and internal rotation. The third test was performed with the lower leg in valgus and external rotation. Force applied was up to the point where resistance occurred without any gross elastic deformation of capsule or ligament in a manner typical of any surgeon assessing the stability of the construct. Also a passive technique of using gravity to ‘Drop-Test’ the limb into flexion and extension gave useful information regarding potential problems such as blocks to extension, over-stuffing of the extensor mechanism and tightness of the flexion gap. All the definitive tests were performed after temporary medial capsular closure.

Ten total knee arthroplasties have been studied using this technique with particular reference to the patterns of instability found before, during and after adjustments to component positioning and ligament balancing. Marked intra-operative variation in the stability characteristics of the trial implanted joints has been quantified before correction. These corrections have been analysed in terms of change in translations, rotations and contact points induced by any such adjustments to components and ligament. Certain major typical patterns of instability have begun to be identified including excessive rotational and translational movements. Instability to valgus and external rotational stress was found in two cases and to varus and internal rotational stress in one case before correction. In particular, surprising amounts of edge loading in mid-flexion under stress testing has been identified and corrective measures carried out. Reductions in paradoxical tibio-femoral antero-posterior motion were also observed. Global instability and conversely tightness were also observed in early stages of surgery. Adjustments to component sizes, rotations, tibial slope angles and insert thickness were found to be necessary to optimise range of motion and stability characterisitics on an almost case-by-case basis. Two cases were identified where use of more congruent or stabilised components was necessary. Observation of quite marked loss of contact between tibia and femur was seen on the lateral side of the knee in deep flexion in several cases. Patellar tracking was also being observed during such dynamic tests and in two cases staged partial lateral retinacular releases were carried out to centre patellar tracking on the prosthetic trochlea.

Although numbers in this case series are small, it has been possible to begin to observe, classify and quantify patterns of instability intra-operatively using simple stress tests. Such enhanced intra-operative information may in future make it possible to create algorithms for logical and precise adjustments to ligaments and components in order to optimise range of motion, contact areas and stability in TKR.

CASN is generally good at bone morphing and sizing, assisting with component orientation, gap balancing and providing reasonably accurate alignments of limb and components alike. However, such routine navigation technique fails to use the full potential of the registered information. Current technique provides reasonable static stability information in the coronal plane, but with axial and sagittal planes less well considered. A more dynamic approach seems to be necessary to define ‘potential envelopes of motion’, seeming to be the best possible way in which CASN will finally show fundamental improvements over ‘conventional’ technique.

Enhanced dynamic assessment using an upgraded CASN system (Brainlab) is now capable of improved ROM analysis and contact point observations. This consists of storing dynamic information including a) epicondylar axis motion, b) valgus and varus alignments, c) antero-posterior shifts, as well as d) flexion and extension gaps. Tracking values for both tibiofemoral and patellofemoral motion can also be obtained after performing registration of the prosthetic trochlea.

Observations can be made using a set of standardised dynamic tests. Firstly, the lower leg can be placed in neutral alignment and the knee put through a flexion-extension cycle. Secondly the test can be repeated but with the lower leg being placed into varus and internal rotation. The third test can be performed with the lower leg in valgus and external rotation. Also a new passive technique of ‘Drop and Push Testing’ into a) flexion and b) extension is giving new information which may prove useful a) in terms of over-stuffing of the extensor mechanism and tightness of flexion gap and b) provision of hyperextension to assist gait. Upgraded software prompts can improve workflows to facilitate optimisation of joint dynamics.

Twenty total knee arthroplasties have been studied using these techniques with particular reference to the patterns of instability found. Marked intra-operative variation in the stability characteristics of the trial implanted joints has been quantified before corrections have been made and final assessments performed. These corrections have also been analysed in terms of change in antero-posterior translations, rotations and contact points. Edge loading and excessive paradoxical motions have been identified and corrective measures carried out, thereby improving PCL tensioning. Component rotations, tibial slope angles, insert thicknesses and femoral sizing have had to be adjusted to optimise range of motion and stability characteristics. Certain cases have been identified where use of more congruent or even stabilised components was considered necessary. Patellar tracking has also been observed during such dynamic tests and appropriate adjustments made to components and soft tissue balancing.

In summary, this study has enabled intra-operative observation, classification and quantification of patterns of instability in 6 degrees of freedom using simple stress tests followed by appropriate adjustments.

Degenerate chondral surfaces can be assessed in many ways, but arthroscopy is often performed without proper categorisation, mapping, zoning or sizing of lesions. Progression of disease in un-resurfaced compartments is well-recognised to occur, but is only one of several failure mechanism in partial knee replacement.

A validated ‘Functional Zone’ mapping method was used to document articular surface damage in 250 sequential cases of knee arthroscopy in patients over the age of 40. Size, shape, location and severity of each chondral lesion were noted using the Outerbridge classification. Analysis determined rates of involvement of particular compartments and assessed potential for partial replacement or local treatment and also to consider the risk of future progression. Radiographs including antero-posterior standing, postero-anterior flexion views (Rosenberg), lateral and skyline views were graded (Kellgren and Lawrence) and compared with the arthroscopic findings.

Our results showed that out of the 210 knees with Grade 3 or greater damage 13.3% of knees showed ‘isolated’ medial disease of Outerbridge Grade 3 or worse. Isolated lateral disease was noted in 1.4%, patello-femoral disease in 24.3%, bi-compartmental (Medial/PFJ) disease in 30.9% with tibio-femoral and tri-compartmental disease seen in 15.2%. The combination of lateral and patello-femoral disease was seen in 14.8%. Provided that Grade 1 and 2 changes (which were found in other compartments in high percentages) were ignored and ACL status considered, this information seemed to indicate that at the time these procedures were performed, 13.3% of cases were suitable for a medial uni-compartmental device, with sub-analysis of lesion sizes indicating that 17 out of 28 cases (60.7%) were suitable for a localised resurfacing. Lateral uni-compartmental replacement seemed suitable for only 1.4%, patello-femoral replacement in 24.3%, bi-compartmental in 30.9% and total knee replacement in 30%. The mean age for partial resurfacing was 53years and 59 years for total joint replacements.

Radiological analysis found that the antero-posterior standing views had only 66% sensitivity and 73% specificity for the presence of Grade 3 changes or worse in the medial compartment in comparison with Rosenberg views having a sensitivity of 73% and a specificity of 83%. Skyline views had a sensitivity of 56% and 100% specificity.

This study indicates that a large proportion of cases may be suited to local and limited resurfacing. Cases suitable for Patello-femoral and Bi-compartmental replacements were very common, but with the patella-femoral joint's tendency to be more forgiving in terms of symptoms, meaning that indications for uni-compartmental replacement might well be much higher than the arthroscopic findings suggested. On the other hand, the presence of high levels of Grade 1 and 2 changes in other compartments seems to indicate a need for caution particularly in younger patients. This study also indicates a need for better methods of assessing local cartilage health such as enhanced MRI scanning or spectroscopy.

Controversy still exists in the literature regarding efficacy and usefulness of CASN in knee arthroplasty. However, obsession with basic alignments and proper correction of mechanical axes fails to recognise the full future potential of CASN which seems to lie in enhanced dynamic assessment. Basic dynamics usually at least includes intraoperative assessment of limb alignments, flexion-extension gap balancing and simple testing through ranges of motion. However our upgraded CASN system (Brainlab) is also capable of enhanced assessment not only including the provision of data on initial to final alignments but also contact point observations. The system can also perform an enhanced ‘Range Of Motion’ (ROM) analysis including observation of epicondylar axis motion, valgus and varus, antero-posterior shifts as well as flexion and extension gaps. Tracking values for both tibiofemoral and patellofemoral motion have also been obtained after performing registration of the prosthetic trochlea.

Observations were then made using a set of standardised dynamic tests. Firstly, the lower leg was placed in neutral alignment and the knee put through a flexionextension cycle. Secondly the test was repeated but with the lower leg being placed into varus and internal rotation. The third test was performed with the lower leg in valgus and external rotation.

We have been able to carry out these observations in a limited case series of 15 total knee arthroplasties and have found it possible to observe and quantify marked intra-operative variation in the stability characteristics of the implanted joints before corrections have been made and final assessments performed. Indeed contact point observation has found several cases of edge loading before corrections have been made. Also ROM analysis has demonstrated the ability of the system in other cases to observe and then make necessary adjustments of implant positions and ligament balance which alter the amounts of antero-posterior and lateral translations. In this way paradoxical antero-posterior and larger rotational movements have been minimised. Cases where conversion to posterior stabilisation has been necessary have been encountered. Also patellar tracking has been observed during such dynamic tests and appropriate adjustments made to components and soft tissue balancing.

Although numbers in this case series are small, it has been possible to begin to observe, classify and quantify patterns of instability intra-operatively using simple stress tests. Such enhanced intra-operative information may in future make it possible to create algorithms for logical adjustments to ligament balance, component sizes, types and positions. In this way CASN becomes a more useful tool.

It is believed by some that knee radiographs may underestimate the extent of osteoarthritis. Often severe changes are noted at arthroscopic assessment despite the observation of preserved joint spaces on plain radiographs. This has important implications regarding the indications for different types of partial joint replacement if damage is underestimated.

Aims:

To determine the correlation if any between radiographic findings and arthroscopic findings.

Methods and patient selection: The pre-operative radiographs and intra-operative articular surface mappings were collected for 100 consecutive patients undergoing prospectively audited outcome of arthroscopic debridement. All the patients examined were aged 40 and above with knee pain. The intra-operative findings and any work done (debridement of meniscal tears or cartilage flap tears) were also recorded on zoned articular maps and meniscal diagrams. The pre-operative radiographs (AP standing, lateral, Rosenberg and skyline views) were examined and graded using the Kellgren and Lawrence grading system.

Results: Correlations made between arthroscopic findings and AP standing views yielded a sensitivity of 72% and specificity of 64%. The positive predictive value was 91% and negative predictive value was 32%. Rosenberg views were better at predicting the presence of osteoarthritis (sensitivity 76%, specificity 88%, positive predictive value 97%, negative predictive value 44%). Skyline views were found to particularly unreliable in assessment of patello-femoral damage. Analysis of the actual patterns of articular damage found at arthroscopy did show that it is possible to identify cohorts of patients who may in future be suitable for different types of partial replacement.

Conclusions: Radiographs and in particular skyline views are limited in terms of sensitivity and specificity in the prediction of osteoarthritis. Rosenberg views offer better prediction of osteoarthritis compared with weight bearing AP radiographs. Arthroscopy carried out in any event for clinical indications appears to offer useful additional information regarding indications for future surgery.

Patellofemoral complications in total knee arthroplasty (TKA) are common. Patellar tracking can be adversely affected by component positioning, soft tissue imbalance and bony deformity. Lateral patellar release rates reported in the literature vary from 6– 40%. Computer assisted surgery has largely been confined to the tibio-femoral component of total knee replacement. However, with recently developed software, it can be used to visualise and quantify patellar tracking and thus guide the precise extent and site of lateral patellar release. The aim of this early study was to define the diagnostic envelope for identification and quantisation of patella maltracking using a current generation patella navigation system.

Our previous prospective analysis of 100 patients undergoing primary TKA identified pre-operative radiographic indices that correlate with maltracking of the patellofemoral joint. 20 cases were subsequently selected for computer assisted total knee replacement surgery. The navigation system (Vector Vision (BrainLab) version 1.6) was used to achieve accurate alignment and position of the femoral and tibial components. All knee replacements were performed using a posterior cruciate-retaining prosthesis. The femoral component was of a ‘patella-friendly’ design with inbuilt 3 degrees external rotation, and the patella was resurfaced in all cases with a biconvex inlay patellar prosthesis.

Patellar tracking was assessed intra-operatively using an additional patellar array and patella tracking-specific software. Real-time displays of patella shift, tilt, rotation and circle radii during multiple flexion-extension cycles were obtained. Where necessary, an ‘outside-to-in’ release of the lateral retinacular complex was performed. The navigation system was used to provide contemporaneous feedback on the effect of the soft tissue releases on the tracking characteristics of the patella component on the prosthetic trochlea. Primary outcomes included the sensitivity and specificity of the system for peri-operative patella maltracking; secondary outcomes included the definition of interventional endpoints and correlation of intra-operative tracking data with post-operative x-rays.

The demographic data for the 20 patients enrolled in this study was essentially unremarkable. As compared to standard intra-operative clinical evaluation of patella tracking, the computer navigation system is equally sensitive and specific, and it can potentially detect more subtle instances of maltracking that may elude conventional clinical evaluation. We present patterns of patellar tracking during the surgery for patient with and without pre-operative patellar maltracking. However, the significance of this is unknown without longer-term outcome data. Patella shift abnormalities that were detected by the system, but not tilt, correlated with clinical judgement of patella maltracking (p< 0.05).

Soft tissue balancing of the patella can now be performed by observing precise changes in shift and tilt. This can be as important as component alignment for optimising patellar tracking and minimising patellofemoral complications.

Introduction: Referrals for Low Back Pain (LBP) are common and many patients appear to see more than one specialist. In one acute trust, a dedicated Spinal Assessment Clinic (SAC) run by nurse practitioners was developed.

Objective: To determine patterns of referral for LBP from primary to secondary care.

Method: All new referrals to the hospital for LBP in an index period June–November 1998 were included. Consultations for these patients in the preceding six months and the subsequent two years were studied.

Results: A total of 801 patients were referred in the audit period. The patients were seen in the SAC 75%, orthopaedics 5.5%, rheumatology 4.5%, neurosurgery 12% and the pain clinic 4%. Onward referrals made after the initial appointment from the SAC 4.9%, from orthopaedics 26.7%, from rheumatology 8.6%, from neurosurgery 33.7% and from the pain clinic 10.3%. Subsequent repeat referrals made by the GP occurred in 3.7%of patients initially seen in the SAC, 11.1% from orthopaedics, 2.9% from Rheumatology, 3.2% from Neurosurgery and 17.2% from the pain clinic. The average wait in days for a first appointment was SAC 42, orthopaedics 103, Rheumatology 82, Neurosurgery 78 and pain clinic 77.

Conclusion: The SAC offers a shorter wait for patients and an extremely low “churn” rate, implying high rates of satisfaction in patients and GP’s. The wait for other specialities is longer, and in orthopaedics and neurosurgery the re-referral rate is almost one third. Referral procedures to secondary care might need to be streamlined for more efficiency.

We designed an experimental study to prove the existence of the popliteofibular ligament (PFL) and to define its role in providing static stability of the knee. We also examined the contribution of the lateral collateral ligament (LCL).

We found this ligament to be present in all eight human cadaver knees examined. These specimens were mounted on a specially designed rig and subjected to posterior, varus and external rotational forces. We used the technique of selective sectioning of ligaments and measured the displacement with a constant force applied, before and after its division. We recorded the displacement in primary posterior translation, coupled external rotation, primary varus angulation and primary external rotation. Statistical analysis using the standard error of the mean by plotting 95% confidence intervals, was used to evaluate the results.

The PFL had a significant role in preventing excessive posterior translation and varus angulation, and in restricting excessive primary and coupled external rotation. Isolated section of the belly of popliteus did not cause significant posterolateral instability of the knee. The LCL was also seen to act as a primary restraint against varus angulation and secondary restraint against external rotation and posterior displacement. Our findings showed that in knees with isolated disruption of the PFL stability was restored when it was reconstructed. However in knees in which the LCL was also disrupted, isolated reconstruction of the PFL did not restore stability.

We measured the effect of arthroscopic lavage and debridement of the osteoarthritic knee by comparing objective measurements of thigh muscle function before and after operation. There was some improvement in quadriceps isokinetic torque at six and 12 weeks after joint lavage but not after debridement. Neither method significantly relieved the patients' symptoms.

We examined the effect of periosteal devascularisation upon the early healing of osteotomies of sheep tibiae held in an instrumented external fixation system with an axial stiffness of 240 N/mm. At 14 days, cortical blood flow measured by the microsphere technique was 19.3 ml/min/100g in the well-vascularised osteotomies, but only 1.7 ml/min/100g in the devascularised osteotomies, despite an increase in medullary flow (p less than 0.0005). Delay in healing of the devascularised osteotomies was suggested by an in vivo monitoring system and confirmed by post-mortem mechanical testing. We suggest that the osteogenic stimulus of dynamic external fixation is dependent on the early restoration of cortical blood flow in devascularised fractures.

There has been a long-standing debate as to whether medullary or periosteal flow is the dominant vascular supply during the healing of diaphyseal fractures. We used radioactive microspheres to quantify blood flow to the canine tibia two weeks after an osteotomy. There was a significant contribution from the periosteum to the blood supply of healing cortical bone after nutrient artery ligation, with a reversal of flow from a centrifugal to a centripetal direction. Our study has confirmed the qualitative observations of Trueta (1974) regarding the significant recruitment of vessels from surrounding soft tissue during fracture healing. We have not studied the later stages of healing.

The uptake of 99mTc-MDP was studied in 73 patients after a tibial fracture. The image obtained five minutes after injection during a period between one and four weeks after fracture was found to be related to the incidence of non-union after six months. A ratio of 1.3 between the uptake at the fracture site and at normal bone adjacent to it predicted non-union in an individual patient with a sensitivity of about 70% and a specificity of 90%.