Current weight-bearing instruction protocols involve non-quantitative guidelines, based on the patient’s amount of discomfort while walking or subjective perception. However, the interpretation of these instructions is inaccurate and subjective, and varies among clinicians and patients. New biofeedback technology concepts are beginning to be implemented in the rehabilitation process. The Smart-Step system is a new weight bearing monitoring system that assists clinicians and physical therapists to accurately assess, train and monitor patients’ weight bearing capabilities.
During treatment, the patients were trained by the PT in FWB according to the instruction of the surgeon. Data of age and body weight was collected from all patients. Patients in both study groups used the SmartStep System. This system consists of an in-shoe inflatable insole, pressure sensors and a control unit for data storage. The control unit provides also an audio signal whenever the patient was bearing body weight at a recommended and pre-calibrated level.
Data obtained in both groups (in kg) during the pre-test and during the gait tests was converted into percentage of the patients BW. The means of the differences between the pre-test results and the gait test results in both groups were 9 + 6.7% and 1.5 + 6% in the study and control group, respectably (p=0.0002).
Positive predictive value calculated for SPECT is 81%, while the negative predictive value calculated is 40%. Separate calculations revealed a PPV of 90.5% in medial meniscal tears and a PPV of 86.7% in lateral meniscal tears respectively. In 13 cases additional inra-articular pathology was noted. In five cases the presumptive diagnosis of a meniscal tear on SPECT was rejected on arthroscopy, in three of these cases the anterior cruciate ligament was injured. One patient with a negative SPECT scan was operated and a meniscal tear found.
Osteochondral lesions are frequent as a result of sport and daily activities. The healing processes of these defects are prolonged and complicated and often leading to irreversible ostheo-arthritic changes. In this study, biotechanical and bioChemical approaches are being combined in an attempt to identify potential uses of biofabricated marine carbonate materials in biomedical applications, particularly as for remodeling cartilage and bone tissue. Biofabricated material was grafted into osteochondral induced defects in animals’ models during knee arthrotomy. Using histological sections, SEM, EDS studies it was revealed that the biofabricated, porous material is highly biocompatible. The graft was incorporated into the osteochondral defect area and followed by surface remodeling. After 4 months the interface and subchondral areas were been replaced by new cartilage and bone. We believe that it is the first time that such biofabricated materials have been used for biomedical purposes. In face of the obvious environmental disadvantages of harvesting from limited natural resources, we propose the use of bio-engineered coralline and other materials such as those cultured by our group under field and laboratory conditions as a possible biomatrix for hard tissue remodeling.