Osteophytes are bony spurs on normal bone that develop as an adaptive reparative process due to excessive stress at/near a joint. As osteophytes develop from normal bone, they are not always well depicted in common imaging techniques (e.g. CT, MRI). This creates a challenge for preoperative planning and image-guided surgical methods that are commonly incorporated in the clinical routine of orthopaedic surgery.

The study examined the accuracy of osteophyte detection in clinical CT and MRI scans of varying types of joints.

The investigation was performed on fresh-frozen ex-vivo human resected joints identified as having a high potential for presentation of osteophytes. The specimens underwent varying imaging protocols for CT scanning and clinical protocols for MRI. After dissection of the joint, the specimens were subjected to structured 3D light scanning to establish a reference model of the anatomy. Scans from the imaging protocols were segmented and their 3D models were co-registered to the light scanner models. The quality of the osteophyte images were evaluated by determining the Root Mean Square (RMS) error between the segmented osteophyte models and the light scan model.

The mean RMS errors for CT and MRI scanning were 1.169mm and 1.419mm, respectively. Comparing the different CT parameters, significance was achieved with scanning at 120kVp and 1.25mm slice thickness to depict osteophytes; significance was also apparent at a lower voltage (100kVp).

Preliminary results demonstrate that osteophyte detection may be dependent on the degree of calcification of the osteophyte. They also illustrate that while some imaging parameters were more favourable than others, a more accurate osteophyte depiction may result from the combination of both MRI and CT scanning.

Metal-on-metal hip resurfacing arthroplasty (MoMHRA) has been a popular alternative treatment for young patients with hip osteoarthritis. Despite its advantages over total hip arthroplasty, the use of MoMHRA remains controversial. Achieving the correct positioning of the prosthetic is a concern due to the difficulty and novelty of this procedure. Furthermore, it has been reported that post-operative management using 2D radiographs contains high degrees of variance leading to poor detection of prosthetic malpositioning. In order to compensate for the lack of available technology, current literature has suggested the use of blood metal ion levels as indirect predictors of prosthetic malpositioning due to the abnormal release of metal ions, particularly Chromium and Cobalt, as a result of increase wear and tear. The purpose of this study was to determine whether 2D/3D registration technology can report prosthetic orientation in vivo and, to establish whether 3D technology can accurately deduce prosthetic wear by correlating prosthetic angles with metal ion counts.

To begin this study, post-operative x-rays (n=72) were used as the two-dimensional media to measure acetabular orientation. Only the acetabular component was examined in this study and acetabular orientation was defined as the function of inclination and version angles. Virtual three-dimensional models of the native, pre-operative pelvises and the acetabular implant were generated and were manually superimposed over the post-operative x-ray images according to anatomical landmarks. A manual 2D/3D registration program was specifically designed for this task. Inclination and version angles of the 2D/3D registered product were measured. Post-operative CT models, which offer the most accurate depiction of the prosthetic in vivo, were generated for validation. Contrary to the study's hypotheses and current literature, no significant difference was observed between 2D vs. 2D/3D vs. CT data, suggesting that 2D and 2D/3D measurements were similar to the results of the gold standard CT model (although 2D/3D measurements were more precise compared to 2D media). Furthermore, statistical analyses revealed no significant correlation in either 2D or 2D/3D compared to metal ion levels, although a stronger trend was demonstrated using 2D/3D measurements. These results are suggestive that 2D/3D registered measurements are equivocal to those using the conventional 2D x-ray and, manual 2D/3D registered measurements do not demonstrate greater efficacy in predicting prosthetic wear. Moreover, the data from this study also revealed insignificant correlations between the angles of acetabular orientation and metal ion release. Combined angles within and beyond the acceptable ranges for inclination (30°–50°) and version (5°–20°) angles did not produce significant trends with metal ion release. These results lead to the paradoxical conclusion that acetabular orientation does not influence prosthetic wear. The findings of this study are inconsistent with the reports in current literature and further investigation is required.

Introduction

Computer-assisted methods for acetabulum cup navigation have shown to be able to improve the accuracy of the procedure, but are time-consuming and difficult to use. The goal of this project was to develop an easy-to-use navigation technique, requiring minimal equipment for acetabular cup alignment.

Introduction

Osteochondral autologous autograft (also called mosaic arthroplasty) is the preferred treatment method for very large osteochondral defects in the ankle. For long-term success of this procedure, the transplanted plugs should reconstruct the curvature of the articular surface. The different curvatures between femoral-patella joint and the dome of the talus makes the reconstruction difficult and requires lots of experience.

Femoroacetabular impingement is a condition in which the femoral head/neck region abnormally contacts the acetabulum, limiting the range of motion of the hip and often associated with pain, damage, and loss of function. The pathophysiology of osteoarthritic changes stemming from impingement syndromes has been linked to the shape of the hip; however, little is known about the influence of the soft tissues to this process.

In this pilot study, we used computer-assisted navigation technology to track motion on a cadaver that had mild bilateral cam-impingement lesions, and then performed a virtual simulation to locate sites of impingement. We hypothesised that soft tissues contribute to the degree and location of impingement, so we compared impingements across three different dissection states: (i) all soft tissues intact; (ii) post-capsulectomy; with only the labrum and ligamentum teres remaining; and (iii) disarticulated, with labrum and ligamentum teres removed.

With ethical approval, we used one fresh frozen cadaver pelvis that was sectioned above the fifth lumbar vertebra and at the knee. The femurs and pelvis were implanted with fiducial screws as an accurate means for surface-based image registration. With all soft tissues intact, tissues were imaged using computed tomography with a slice thickness of 0.625 mm. The CT scans were imported into Mimics (v13.0, Materialise, Belgium) and carefully segmented, with particular detail to the articular regions and fiducials, to create 3D digital models of the pelvis and femurs.

On each side, optical local coordinate reference (LCR) bodies were attached at the proximal femur and iliac crest to permit spatial tracking with an Optotrak Certus camera (Northern Digital Inc., Waterloo, Canada). The 3D digital models were imported into the VSS navigation system (iGO Technologies, Kingston, Canada) and scrupulously registered to the anatomy using the fiducial screws and a calibrated probe. The pose of the femur and pelvis were recorded throughout a series of twelve movements involving various combinations of flexion-extension, abduction-adduction, internal-external rotation and circumduction, as well as functional movements typical of a clinical hip screening. Soft tissues were selectively removed and the movements were repeated post-capsulectomy and completely disarticulated.

The recorded pose data were applied to the 3D digital models to perform a computational simulation of the movements during the trials. The pose data were expressed in coordinates of the anterior pelvic plane to compute angles of motion in the principal directions (flexion, abduction, rotation). The motion data were further filtered so that only comparable ranges of motion were present for data analysis. Algorithms were developed to determine bone-on-bone impingement locations by finding contact points between the models.

Impingement locations were plotted on the digital models of the femur and pelvis in order to establish zones of impingement. The surface area of each impingement zone was computed by using a Crust-based algorithm that triangulated impingement points encompassing a region, and then summed the surface area of each triangle to estimate the total impingement surface area.

Upon visual inspection, it was immediately apparent that impingements tended to occur in well-defined regions. On the femur, these were found along aspects of the head-neck junction, especially on or near osteophytes. On the pelvis, impingement regions were found along the acetabular rim and extending into the lunate region.

With soft tissues intact, both femurs and pelvis had prominent anterior and posterior impingement zones. In contrast, post-capsulectomy impingement zones were predominately confined to the anterior region. It should be noted, however, that the total impingement area decreased post-capsulectomy, representing only about 25% of the total area of impingements when all soft tissues were intact. This was also true in the disarticulated state.

Both femurs had mild posterior cam lesions, the right worse than the left. Impingements were seen at these sites with soft tissues intact, but diminished almost entirely post-capsulectomy. The anterior lesions were located contra coup to these cam lesions.

With soft tissues intact, impingements tended to occur in external rotation and abduction. With soft tissues removed there was a pronounced shift towards impingements occurring in internal rotation. Impingements were also noted in large flexion angles and large abduction-adduction angles in the absence of soft tissues.

Although it is widely accepted that the hip is spherical in shape and has ball-and-socket kinematics, recent work suggests that the osteoarthritic hip is aspherical and that translational motion is present. On a very limited series, this work is supportive of the latter observation: if hip motion is purely spherical, a decrease in impingements post-capsulectomy is exceedingly hard to describe. However, if soft tissues cause translatory motion, then their absence logically should lead to a change in the impingement pattern (which we found).

This preliminary study provides a methodology for studying the effects of soft tissue on impingements. We conclude that soft tissues do indeed play an important role in impingement and may even contribute to the development of impingement lesions. Limitations include a small sample size, so further studies are required prior to conclusively establishing impingement patterns in passive kinematics of cadaver hips.

Hip Resurfacing Arthroplasty (HRA) is a surgical technique that has become more popular in recent years for the treatment of hip osteoarthritis in young patients. For these patients, an HRA offers the advantages of preserving the physiologic anatomy of a patient's femoral head size and neck offset, which has been theoretically suggested to improve range of motion and muscle function, as well as preserving bone stock for future revision surgeries. Although the improvements in quality of life outcomes in patients undergoing total hip arthroplasty (THA) are well-documented, there is a lack of literature documenting the improvements in quality of life in patients undergoing HRA.

The purpose of this study was to compare the accuracy and precision of acetabular component placement in cadavers using conventional techniques and CT-based individualised guides by both orthopaedic trainees and surgeons.

Seven cadaveric pelvises underwent a computerised tomography (CT) scan and a three-dimensional virtual model was created. Based on this model, cup orientation was planned for 40 degrees of inclination and 20 degrees of anteversion and an individualised guide was designed. A physical model of the individualised guide was created using a Rapid Prototyping machine (dimension SST, Stratasys, Inc., USA).

The pelvises were mounted in the lateral position and covered with a soft tissue envelope exposing only the acetabulum as would be visualised during a lateral approach to the hip. A total of 26 participants (16 orthopaedic surgery residents, 10 orthopaedic surgeons) were asked to use an acetabular cup impactor to place the cup in 40 degrees of inclination and 20 degrees of anteversion. This was first completed for all seven pelvises using conventional placement. Each participant was then instructed on how to use the individualised guide. They were provided with the guide and an individualised acetabular model to practice placement. Once they were comfortable with the system they were then asked to use the individualised guides in each of the seven pelvises.

An optoelectronic navigation system was used to evaluate the accuracy of the placement of the acetabular cup. An Optotrak Certus Motion Tracking System (Northern Digital Inc., Waterloo, Canada) was used. An optoelectronic marker was attached to the acetabulum and a combined pair-point and surface matching was performed. After the guide was placed in the acetabulum, a tracked axial pointing device was aligned inside the guidance cylinder and its three-dimensional orientation stored. The angle deviation between the achieved position and the planned cup orientation was calculated.

There were no statistically significant differences between trainees and surgeons in either conventional placement or use of the individualised guides. There were no statistically significant differences in anteversion between the groups. The individualised guide showed statistical improvement in the absolute deviation from planned inclination compared to conventional placement (4.2° vs. 9.1°, p< 0.001) as well as a reduction in standard deviation (3.3 vs. 5.9, p< 0.001).

The use of individualised guides can improve the accuracy and precision in the placement of acetabular component positioning. The current guide design controls well for inclination, which is a key factor in the function of a total hip arthroplasty. Based on this data, we will implement design changes to better address version of the component. Future work will likely include comparison to computer-assisted cup placement as well.