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Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_14 | Pages 4 - 4
23 Jul 2024
Roberts RHR Shams N Ingram-Walpole S Barlow D Syed A Joshi Y Malek I
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Periprosthetic joint infections (PJIs) and osteosynthesis-associated infections (OSIs) present significant challenges in trauma and orthopaedic surgery, substantially impacting patient morbidity, mortality, and economic burden. This concern is heightened in patients with pre-existing comorbidities, such as diabetes mellitus, which are not always modifiable at presentation. A novel intraoperative strategy to prevent these infections is the use of Defensive Antibacterial Coating (DAC), a bio-absorbable antibiotic-containing hydrogel applied to implant surfaces at implantation, acting as a physical barrier to prevent infection.

The purpose of this study is to assess the use of a commercially available hydrogel (DAC), highlighting its characteristics that make it suitable for managing PJIs and OSIs in orthopaedics and traumatology. Twenty-five patients who underwent complex orthopaedic procedures with intraoperative application of DAC between March 2022 and April 2023 at a single hospital site were included. Post-operative assessment encompassed clinical, laboratory, and radiographic examinations.

In this study, 25 patients were included, with a mean age of 70 ± 14.77 years and an average ASA grade of 2.46 ± 0.78. The cohort presented an average Charleston Comorbidity score of 5.45 ± 2.24. The procedures included 8 periprosthetic fractures, 8 foot and ankle surgeries, 5 upper limb surgeries, and 4 elective hip and knee surgeries. Follow-up assessments at 6 weeks and 6 months revealed no evidence of PJI or OSI in any patients, nor were any treatments for PJI or OSI required during the interim period.

DAC demonstrated efficacy in preventing infections in high-risk patients undergoing complex orthopaedic procedures. Our findings warrant further investigation into the use of DAC in complex hosts with randomized control trials.


Aims

Classifying trochlear dysplasia (TD) is useful to determine the treatment options for patients suffering from patellofemoral instability (PFI). There is no consensus on which classification system is more reliable and reproducible for the purpose of guiding clinicians’ management of PFI. There are also concerns about the validity of the Dejour Classification (DJC), which is the most widely used classification for TD, having only a fair reliability score. The Oswestry-Bristol Classification (OBC) is a recently proposed system of classification of TD, and the authors report a fair-to-good interobserver agreement and good-to-excellent intraobserver agreement in the assessment of TD. The aim of this study was to compare the reliability and reproducibility of these two classifications.

Methods

In all, six assessors (four consultants and two registrars) independently evaluated 100 axial MRIs of the patellofemoral joint (PFJ) for TD and classified them according to OBC and DJC. These assessments were again repeated by all raters after four weeks. The inter- and intraobserver reliability scores were calculated using Cohen’s kappa and Cronbach’s α.


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_4 | Pages 3 - 3
3 Mar 2023
Roy K Joshi P Ali I Shenoy P Syed A Barlow D Malek I Joshi Y
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Classifying trochlear dysplasia (TD) is useful to determine the treatment options for patients suffering from patellofemoral instability (PFI). There is no consensus on which classification system is more reliable and reproducible for this purpose to guide clinicians in order to treat PFI. There are also concerns about validity of the Dejour classification (DJC), which is the most widely used classification for TD, having only a fair reliability score.

The Oswestry-Bristol classification (OBC) is a recently proposed system of classification of TD and the authors report a fair-to-good interobserver agreement and good-to-excellent intra-observer agreement in the assessment of TD. The aim of this study was to compare the reliability and reproducibility of these two classifications.

6 assessors (4 consultants and 2 registrars) independently evaluated 100 magnetic resonance axial images of the patella-femoral joint for TD and classified them according to OBC and DJC. These assessments were again repeated by all raters after 4 weeks. The inter and intra-observer reliability scores were calculated using Cohen's kappa and Cronbach's alpha.

Both classifications showed good to excellent interobserver reliability with high alpha scores. The OBC classification showed a substantial intra-observer agreement (mean kappa 0.628)[p<0.005] whereas the DJC showed a moderate agreement (mean kappa 0.572) [p<0.005]. There was no significant difference in the kappa values when comparing the assessments by consultants to those by registrars, in either classification systems.

This large study from a non-founding institute shows both classification systems to be reliable for classifying TD based on magnetic resonance axial images of the patella-femoral joint, with the simple to use OBC having a higher intra-observer reliability score compared to the DJC.


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_10 | Pages 5 - 5
1 Oct 2015
Babu A Joshi Y Lewis K Singh R
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Aim

To determine effectiveness of Collagenase Clostridium Histolyticum (CCH) in deformity correction and hand function for patients with Dupuytren's disease.

Materials & Methods

Patients with MCPJ contractures with no previous surgery to the same finger were included. Treatment consisted of one Xiapex injection to a prominent pretendinous band as an outpatient procedure. Follow up was arranged at 48 hours, 3 weeks and final follow up > 6 months.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_19 | Pages 16 - 16
1 Apr 2013
Shah A Badge R Joshi Y Choudhary N Sochart D
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Introduction

Negative remodelling of the femoral cortex in the form of calcar resorption due to stress shielding and cortical hypertrophy at the level of the tip of the implant, due to distal load transfer, is frequently noted following cemented total hip replacement, most commonly with composite beam implants, but also with polished double tapers. The C-stem polished femoral component was designed with a third taper running from lateral to medial across and along the entire length of the implant, with the aim of achieving more proximal and therefore more natural loading of the femur. The hoop stresses generated in the cement mantle are transferred to the proximal bone starting at the calcar, which should theoretically minimise stress-shielding and calcar resorption, as well as reducing distal load transfer, as signified by the development of distal femoral cortical hypertrophy.

Materials/Methods

We present the results of a consecutive series of 500 total hip replacements performed between March 2000 and December 2005 at a single institution, using a standard surgical technique and third generation cementing with Palacos-R antibiotic loaded cement. Data was collected prospectively and the patients remain under annual follow-up.

500 arthroplasties were performed on 455 patients with an average age of 68.3 years (23–92). 77 patients have died (73 arthroplasties) and the average duration of follow-up for the entire series is 81 months (52–124).


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_19 | Pages 13 - 13
1 Apr 2013
Badge R Shah A Joshi Y Choudhary N Sochart D
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Introduction

Traditionally the use of small diameter femoral head (22mm) with the posterior approach has been perceived as an increased risk of dislocation. We present this prospective study of 400 consecutive total hip replacements performed using a 22mm femoral head and the posterior approach.

Materials/Methods

Between March 2000 and November 2005 364 patients underwent 400 total hip replacements with a small diameter 22mm head under the care of four different consultants, using a standard posterior approach. All of the femoral implants were cemented using modular C-stems (Depuy Ltd.) and all of the acetabular components were cemented flanged monobloc all-polyethylene components with long posterior wall with a third generation cementing technique. A standard posterior approach was used in all cases, with direct repair of the capsule and short external rotators.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_21 | Pages 17 - 17
1 Apr 2013
Stevenson J Tong A Joshi Y Laing P Makwana N
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Introduction

Patients who present with atypical foot pain in a non specific sensory distribution may benefit from having nerve conduction studies (NCS). The aim of this study was to confirm whether NCS is a useful tool.

Methods

Between July 2005 and March 2011, 78 patients had NCS to investigate foot pain. The management following NCS was compared with the initial management plan.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IV | Pages 64 - 64
1 Mar 2012
Peter V Joshi Y George H Bass A
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Introduction

Some patients with Cerebral Palsy who had a de-rotation osteotomy performed for correction of excessive anteversion had persistence of internal foot progression even after surgery. Potential causes which have been implicated include: weak hip abductors, spasticity of the anterior fibres of the gluteus medius, hip adductor spasm and persistent femoral anterversion. The aim of this study was to see if there is any relationship between significant abductor weakness [less than Grade III: MRC] and persistence of internal foot progression.

Methods

We included all ambulatory patients with cerebral palsy who had had a derotation osteotomy between the periods of 2000-2005, who had also had a pre and post operative gait analysis, assessment of anteversion [Gage Test], hip range of motion and muscle charting.

There were 12 patients [17 hips, 5 bilateral] with an average age of 13. Seven were diplegic, two hemiplegic and three had asymmetric diplegia. Data was assessed using SPSS13.0. The Spearman Co-relation Coefficient was used to test if there was any correlation.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IV | Pages 9 - 9
1 Mar 2012
Joshi Y Ali M Pradhan N Wainwright O
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Introduction

We conducted a study of 312 patients undergoing primary hip and knee arthroplasty in 2005. The aim was to identify the correlation between length of stay, ASA (American society of Anaesthesiologist) grade and BMI (Body Mass Index).

Method and materials

312 patients underwent hip and knee arthroplasty in 2005. ASA grade for surgery was documented by the anaesthetist and BMI by the nurses. 67 patients had inadequate documentation. SPSS software was used for analysis.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 504 - 504
1 Oct 2010
Joshi Y Agrawal Y Phaltankar P Quah C
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Purpose of Study: To prospectively evaluate the outcome of single surgeon endoscopic anterior cruciate ligament (ACL) reconstruction with quadrupled hamstring tendons drilling femoral tunnel independent of the tibial tunnel.

Methods and Results: 28 patients underwent endoscopic ACL reconstruction by a single surgeon in a DGH setting. All patients had symptomatic ACL deficiency proven by either MRI or previous arthroscopy. All patients were prospectively scored using the International Knee Documentation Committee (IKDC) score, the Lysholm score, Tegner activity score and the SF36 score. In each patient, an ipsilateral four-strand semi-tendinosus/gracilis tendon graft was used. The femoral tunnel was drilled through the anteromedial portal independent of the tibial tunnel as per the technique described by Leo Pinczewski, Sydney, Australia. This technique was used to place the femoral end of the graft in a more lateral position than obtained by the traditional transtibial technique. The ACL graft was fixed using RCI interference screws. All patients underwent standard accelerated rehabilitation program. All patients were reviewed clinically and radiologically at a mean follow-up 9 months. A significant improvement was noted in all the scores at the time of follow-up. Radiologically all femoral and tibial tunnels were satisfactorily placed with the femoral tunnels being in the 10 o’clock or 2 o’clock position with no evidence of tunnel widening. None of the grafts had failed. We feel that this technique may allow better rotational stability following ACL reconstruction.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 595 - 595
1 Oct 2010
Joshi Y Bass A Peter V
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Purpose: The aim of this study was to see if there is any relationship between a positive hamstring shift test, which is a measure of knee flexion deformity after eliminating pelvic tilt with anterior pelvic tilt during the gait cycle.

Methods: We included all patients with cerebral palsy who had a gait analysis and a full physical assessment including measurement of the popliteal angle and hamstring shift test between August and December 05. The difference in measurement of knee flexion between the popliteal angle at 90 degrees and the hamstring shift test was termed hamstring length (HL). There were 33 patients of which 9 [18 limbs] were selected who fulfilled the criteria of a significant positive hamstring shift [> 10 degrees difference]. Maximum dynamic hip extension and average pelvic tilt were estimated from the gait analysis graph. SPSS13.0 was used to analyse the data.

Results: Mean HL was found to be 15.28 degrees. 6 (33.3%) patients had average pelvic tilt < 5 degrees, 8 (44.4%) was between 5–10 degrees and 4 (22.2%) patients had pelvic tilt of more than 10 degrees. The data had a normal distribution. There was no co relation between HL and pelvis tilt [p value:0.363 and r= −0.228.] or between average anterior pelvic tilt and the hip fixed flexion deformity. (p=0.361). However, it was found that maximum dynamic hip extension had strong negative association with average pelvic tilt (p=0.05, r = −0.455).

Conclusion: This study suggests that hamstring shift test does not have any correlation with pelvic tilt. In patients with a positive hamstring shift test, correcting the pelvic tilt will not correct the flexion deformities of the knee.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 595 - 595
1 Oct 2010
Joshi Y Bass A Peter V
Full Access

Purpose: Some patients with Cerebral Palsy who had a de-rotation osteotomy performed for correction of excessive anteversion had persistence of internal foot progression even after the surgery. The aim of this study was to see if there is any relationship between significant abductor weakness [less than Grade III: MRC] and persistence of internal foot progression.

Methods: We included all ambulatory patients with cerebral palsy who had had a de-rotation osteotomy between the periods of 2000 – 2005, who had also had a pre and post operative gait analysis, assessment of anteversion, muscle charting and hip range of movements. There were 12 patients [17 hips, 5 bilateral] 5 male 7 female with an average age of 13. Seven were diplegic, two hemiplegic and three had asymmetric diplegia. Data was assessed using SPSS 13.0. As the data was found to be normally distributed the Fisher exact test and the Spearman’s Co-relation Coefficient was used.

Results: Of the 17 limbs operated, preoperative femoral anteversion was 20–60 degrees [mean: 45] and post op femoral anteversion was 0–35[mean: 15]. Of these 7 hips had persistent internal rotation gait on gait analysis. None of these patients with persistent internal rotation had any hip capsular contractures, and there was no significant change in abductor power after surgery. On testing the hypothesis it was found that there is no relationship between weak hip abductors and persistent internal rotation. [Fisher exact test: p value: 0.8, r = −0.07]

Conclusion: Weak abductors may not be a cause of persistent internal rotation following de-rotation osteotomy. Weak abductor power is not a contraindication to de-rotation osteotomies and do not affect outcome of surgery.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 498 - 498
1 Oct 2010
Quah C Chougle A Joshi Y Mcgraw P
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Introduction: Elective joint replacement patients routinely require transfusion following surgery. Haemoglobin must remain within red blood cells in order to be functional. The process of surgery and collection in the reinfusion drain may disrupt cell membranes resulting in non functional haemoglobin. The filtration and collection process does not eliminate free haemoglobin. This results in intracellular and free haemoglobin being transfused into patients giving false functional haemoglobin levels.

Aim: To determine the proportion of intracellular haemoglobin in autologous blood transfusion drain following joint replacement.

Research Methodology: Research ethical approval was obtained prior to conducting this study. 20 consecutive patients undergoing elective total hip replacement (THR) and 20 consecutive patients undergoing elective knee replacement (TKR) from April 08–July 08 were consented to participate in this study. A standard full blood count sample of 3 mls was taken from the rein-fused blood. Each sample had the total haemoglobin (THb) concentration determined (i.e. free and intra-cellular) from the blood in the specimen tube. The sample was then centrifuged, and the THb of the supernatant was determined. This determined the concentation of ‘free’ haemoglobin. From these two respective values, the proportion of haemolysed haemoglobin was determined from each sample.

Results: There were a total of 35 participants of which 20 were TKR and 15 were THR. The average THb concentration for the THR and TKR were 7.7g/dl and 10.3g/dl respectively. The proportion of haemolysed Hb was 1.46% and 0% respectively. The THb and proportion of haemolysed Hb for all 35 patients were 8.76g/dl and 0.63%.

Conclusion: Autologous blood transfusion is not only safe and economical but remains an effective procedure with a negligible proportion of haemolysis


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_III | Pages 370 - 370
1 Jul 2010
George HL Joshi Y James LE Shivrathri D Bruce CE
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Purpose: Scarf osteotomies are commonly performed in adults with symptomatic bunions. We have reported the radiological and clinical outcome of this procedure in the treatment of moderate to severe hallux valgus among adolescent children.

Methods: Data was collected retrospectively from a tertiary referral children hospital between April 2001 and June 2006. The pre and postoperative intermetatarsal angle (IMA), hallux valgus angle (HVA) and distal metatarsal articular angle (DMAA) were determined. Patients were followed up for a mean of 8.6 months (3–18).

Results: 23 scarf osteotomies were performed in 16 patients with a mean age of 14.3 years (12–18). The mean pre operative IMA of 14.4 degrees was improved to a postoperative value of 9.3 degrees, p< 0.0001. The mean HVA angle was improved from 34.7 to 16.5 degrees, p< 0.0001. The DMAA was improved from 13.1 to 8 degrees, p< 0.0001. There were 2 cases of superficial wound infections successfully treated with oral antibiotics. One patient developed a complex regional pain syndrome that resolved with physiotherapy and analgesia.

Conclusion: We believe that scarf osteotomy is a safe and effective option for the management of the adolescent symptomatic bunions.

Significance: There are no published reports in the English literature of scarf osteotomy in the management of adolescent children with symptomatic hallux valgus. The aim of this paper is to report the radiological and clinical outcome of scarf osteotomy in the treatment of moderate to severe hallux valgus among adolescent children.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 522 - 522
1 Aug 2008
George HL Joshi Y James LA Garg N Bruce CE
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Purpose of Study: To present the clinical features, investigations, histopathology, differential diagnosis and treatment options for lipoblastoma, based on a series of six encountered in our paediatric orthopaedic practice.

Method: The records of six children with lipoblastoma who attended Alder Hey Hospital between 2000 and 2006 were reviewed. Mean age was 17 months and mean follow up was 26 months.

Results: The youngest was a six month old infant with a swelling on his right instep. The second patient, a three year old girl, presented with a limp and swelling in her foot. The third patient was an 18 month old boy with a swelling on the dorsum of his left forearm. The fourth patient had a swelling of his left thigh and two patients had swellings in their backs. Each was investigated by MRI (1), CT (1) or US (4) and surgical excision planned accordingly. There were no post operative complications. None has shown recurrence during follow-up.

Conclusions: All patients were originally thought to have simple lipomata or soft tissue swellings. This is primarily because lipoblastoma is a rare tumour, yet lipoblastoma is the most likely diagnosis of a fatty lump in a child aged less than two. Differential diagnoses include myxoid liposarcoma, well-differentiated liposarcoma, spindle cell lipoma, typical lipoma and soft tissue sarcoma.

Lipoblastomata need thorough imaging. Cytogenetic evaluation of tumour cells often reveals chromosomal anomalies, such as abnormalities of the long arm of chromosome 8 leading to rearrangement of the PLAG1 gene. Biopsy of the lesion is recommended for accurate diagnosis, as clinical and radiological diagnoses can be misleading.

Lipoblastomata tend to spread locally and may recur after incomplete resection; metastatic potential has not been reported. Complete surgical resection is mandatory to prevent recurrence.