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Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_15 | Pages 41 - 41
1 Dec 2021
VANCOMYCIN BONE AND TISSUE CONCENTRATIONS FOLLOWING TIBIAL INTRAOSSEOUS ADMINISTRATION: EVALUATED IN A PORCINE MODEL
Kipp JO Hanberg P Slater J Nielsen LM Jakobsen SS Stilling M Bue M
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Background

Systemically administered vancomycin may provide insufficient target-site concentrations. Intraosseous vancomycin administration has the potential to overcome this concern by providing high target-site concentrations.

Aim

To evaluate the local bone and tissue concentrations following tibial intraosseous vancomycin administration in a porcine model.

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