Dislocations have impact on quality of life, but it is difficult to quantify this impact for each patient. The Quality-of-Life Time Trade-Off assesses the percentage of a patient's remaining life that the patient would be willing to trade for perfect health [1]. This technique has been used for non-unions [2], but never proposed for dislocation.

154 patients (with 3 recurrent dislocations) undergoing revision were asked to choose between living with their associated dislocation risk or trading a portion of their life expectancy for a period of perfect health without dislocation, thus determining their Quality-of-Life score. This score may range from 0.1 (willing to trade nine years among 10) to 1.0 (unwilling to trade any years). Additionally, patients were assessed on their willingness to trade implant survival time for a reduced risk of dislocation, considering various implant options that might offer lower (but not necessary) survival time before revision than the theoretical best (for the surgeon) “standard” implant, thus determining a “Survival Implant Quality” score.

Patients diagnosed with 3 hip dislocations have a low health-related quality of life. The score of our “dislocation” cohort was average 0.77 with patients willing to trade average 23% of remaining lifespan for perfect health (range 48% to 12%). This score is below that (0.88) of illnesses type-I diabetes mellitus [3] and just higher than tibial non-union (0.68) score [2]. The mean “Survival Implant Quality” score of our recurrent dislocation cohort was 0.71 (range 0.59 to 0.78) which means that patients accept to trade average 3 years (range 2 to 4 years) among 10 theoretical years of survival of the implant.

Hip dislocation has a devastating impact that can be quantified for each patient when discussing revision and choice of implants for instability.

For references, please contact the author directly.

The purpose was to determine the lifetime risk of re-operation due to specific complications related to dual mobility using re-operation as a competing risk, excluding loosening, periprosthetic fracture, and infection.

1503 mono-block dual mobility total hip arthroplasty (DM-THAs). Defining the re-operation when anesthesia (for dislocation) and revision when the implant changed. Surgery (801 for primary, 702 for revision with 201 for recurrent dislocation and 501 for loosening) performed between 1990 and 2020 in average 81-year-old (range 50–102) patients, with 522 living patients at 10 years follow-up.

During the first month, outer dislocation (60 cases; 4%) was the cause re-operation (1% among primary and 6 % among revisions). Twenty-four intra-prosthetic dislocations (IPD) were an iatrogenic consequence of a failed closed reduction (reduction maneuver dissociating the inner head) with 1.6% revision.

Between 1 month and 1 year, 22 new outer dislocations, while 25 of the 60 “first month” dislocations had recurrent dislocation. Fifteen other IPDs as iatrogenic consequences were observed. At one year, the cumulative revision was 3% (49 of 82 dislocations).

Between 1- 10-year FU, 132 other dislocations, and 45 other revisions for dislocations were observed. Corrosion was another cause of revision (37 cases): between the cobalt-chromium shell and the femoral neck (23 hips), or 14 crevice corrosion between the trunnion and the metal head (trunnion damage).

In summary, at 10-year: dislocation first cause of re-operation (214 anesthesia, 14%), while among 131 revisions (8.9 %) the 55 iatrogenic intra-prosthetic dislocations were the first revision cause before 39 recurrent dislocations and 37 corrosions.

The 522 patients followed ten years or more had a 15% risk revision due to DM specific complications during their lifetime and 10% more risk associated with loosening (6%), periprosthetic fracture (2%) and infection (2%).

The variables involved in a robotic THA can exceed 52: many parameters as pelvic orientation with CT scan, templating, offset, and leg-length, acetabular reaming, femoral osteotomy, mapping the anatomy; predefining safe zones, robotic execution, femoral head size, thickness of PE etc. with several variables for each parameter, with a total number of variables exceeding 52. This familiar number is the number of cards in a standard deck. The number of possible combinations (factorial 52! = 10^67) to shuffle the cards (and may be to perform a THA) is greater than the number of atoms on earth! Thinking that artificial intelligence and robotics can solve these problems, some surgeons and implant manufacturers have turned to artificial intelligence and robotics.

We asked two questions:1) can robot with artificial intelligence really process 52 variables that represent 10^67 combinations? 2) the safety of the technology was ascertained by interrogating Food and Drug Administration (FDA) database about software-related recalls in computer-assisted and robotic arthroplasty [1], between 2017 and 2022.

1)

The best computers can only calculate around 100 thousand billion combinations (10^14), and with difficulty: it takes more than 100 days to arrive at this number of digits (10^14) after the decimal point for the number π (pi). We can, therefore, expect the robot to be imperfect.

Hip surgeon is as intelligent as a robot and almost twice as safe.

Symptomatic and non-symptomatic hip osteonecrosis related to sickle cell disease (SCD) has a high risk of progression to collapse and total hip arthroplasty (THA) in this disease has a high rate of complications. We asked question about the benefit of performing an IRM to detect and treat with cell therapy an early (stage I or II) contralateral osteonecrosis.

430 consecutive SCD adult (32 years, 18 to 51) patients (225 males) with bilateral osteonecrosis (diagnosed with MRI) were included in this study from 1990 to 2010. One side with collapse was treated with THA and the contralateral without collapse (stage I or II) treated with cell therapy. The volume of osteonecrosis was measured with MRI. For cell therapy, the average total number of mesenchymal stem cells (MSCs) counted as number of colony forming units-fibroblast injected in each hip was 160,000 ± 45,000 cells (range 75,000 to 210,000 cells).

At the most recent FU (20 years, range 10 to 30), among the 430 hips treated with cell therapy, 45 hips (10.5%) had collapsed and had required THA at 10 years (range 5 to 14 years) and 380 hips (88%) were without collapse and asymptomatic (or with few symptoms) with a decrease percentage of necrosis on MRI from 45% to 11%. Among the 430 contralateral THA, 96 (22.3%) had required one revision, 28 had a re-revision, and 12 a third re-revision with aseptic loosening (85% of revisions) and/or infection (6% of revisions). Hips undergoing cell therapy were approximately three times less likely to undergo revision or re-revision surgery (p < 0.01) as compared with hips undergoing a primary THA.

THA is the usual treatment of collapsed ON in patients with SCD. In this population, it is worth looking with MRI for an early stage on the contralateral hip and performing (when necessary) bone marrow cell implantation during the same anesthesia as for arthroplasty.

We questioned about bearing surface and infection in two populations of patients who had bilateral THA with different bearings performed in the same hospital by the same surgical team from the year 1981 to the year 2010 (mean followup 15 years; 7 to 35).

1) first population (mean age 32 years): 325 patients (650 hips) with sickle cell disease (SCD) with two different bearing on each side. 116 patients had Metal on PE (MoP) on one side and Ceramic on PE (CoP) on the contralateral; 106 patients had (CoP) and Ceramic on Ceramic (CoC); 103 patients had MoP and CoC. 2) matched control population (same age, same period) of 820 patients without co-morbidities: 354 patients had MoP and CoP; 237 had CoP and CoC; 229 had MoP and CoC.

Among the 2290 hips, 3 early (less than 12 months) unilateral infections (2 in the controls, 1 in the SCD), and 59 late unilateral infections: 23 (1.4%) in 1640 THAs control, versus 36 (5.5%) in the SCD 650 THAs (P < 0.0001) during the observation period of 35 years.

In control group with the Kaplan-Meier analysis, increase infections over time but different (p=0.02) for each bearing surfaces, respectively from 0% at one year to 0.4% revision (2 cases) at most recent follow-up for 466 CoC hips, from 0% to 1.1% (7 cases) for 591 CoP hips, and from 0.3% to 2.4% (14 cases) for 583 MoP hips.

In sickle cell disease group MoP hips had higher risk of infection (26 among 219) when compared with CoP (9 among 222; p=0.002), and CoC (1 among 209 hips; p=0.0004); with increase over time from 1% at one year to 4% with CoP, and from 1% to 11.8% with MoP.

When contralateral hip of same patient is control, PE components are more prone to infection than those involving ceramic-on-ceramic.

It is unknown whether the risk of periprosthetic femoral fracture is the same in patients with two different bearing surfaces, ceramic on ceramic (CoC) and ceramic on polyethylene (CoP).

We retrospectively reviewed selected 126 patients (252 hips) with bilateral THA (one ceramic-ceramic, AL/AL and the contralateral ceramic-polyethylene, AL/PE) who had THA performed between from 1981 to 1985 for osteonecrosis. Surgery was performed in patients who were average 50 years (range 30–60) old. The stem was always cemented and the same for both sides. The alumina head was 32 mm in diameter. The acetabular component was a polyethylene cup or an alumina cup and was always cemented. The mean follow-up for living patients was 35 years (range 32 to 36), and the mean follow-up for patients who had died was 23 years range 15 to 30).

14 periprosthetic fractures occurred in 252 hips after THA, representing an overall prevalence of 5.5% for hips and 11% for patients. Periprosthetic fractures increased in number with followup: 3 patients (3%) sustained fractures within 10 years of their primary implantation, 7 within 20 years, 10 within 30 years, 14 (11%) within 35 years. The risk of fracture was influenced (p=0.01) by the bearing surfaces at the time of prosthetic implantation, low (1%) for ceramic on ceramic (1/14 fractures; 1/126 hips), higher (10%) for ceramic on PE (13/14; 13/126).

When the contralateral hip of the same patient is the control, the long-term risk of periprosthetic fracture on the side with PE cup is greater (10%) than on the side with ceramic/ceramic bearing.

Background

Definitive proof is lacking on mesenchymal stem cell (MSCs) cellular therapy to regenerate bone if biological potential is insufficient. High number of MSCs after GMP expansion may solve the progenitor insufficiency at the injury but clinical trials are pending.

Total hip arthroplasty (THA) has been efficacious for treating hip fractures. However, in these patients with fractures a widely variable prevalence of dislocation has been reported, partly because of varying durations of follow-up for this specific end-point. The purpose of the present study was to determine the risk of dislocation as a function of time after total hip arthroplasty in these patients with fractures and to investigate if constrained liners influence the cumulative risk of dislocation.

Between 2000 and 2005, 425 patients with neck fracture underwent primary THA using a constrained acetabular liner (Cemented retentive cup, Groupe lépine, Genay, France). The results of these 425 constrained acetabular liners were compared with 380 THA without constrained liners performed for neck fractures between 1994 and 1999 in the same hospital. All patients were followed for a minimum of 5 years for radiographic evidence of implant failure. The patients were followed at routine intervals and were specifically queried about dislocation. The cumulative risk of dislocation was calculated with use of the Kaplan-Meier method.

Introduction

This study reports the results of percutaneous autologous bone marrow grafting in 62 patients with corticosteroids treatment who had one hip osteonecrosis treated with bone marrow (BM) injection and the other contralateral hip osteonecrosis with core decompression (CD) alone. Only patients with bilateral symptomatic osteonecrosis and with those hips at stage I or II (as defined by Steinberg) were included in this study.

Purpose of the study: When the acetabular component is revised alone, if the femoral stem has not been loosened, the question becomes what should be done about the osteolysis of the femur: Change the femoral piece systematically and graft the osteolysis? Curettage and grafting of the osteolysis? Curettage alone? This study reports the outcome of superior femoral osteolysis with a calcar granuloma and no other procedure (no curettage) after replacing the cup.

Material and methods: This was a retrospective analysis of 54 acetabular revisions performed from 1988 to 1998. The cemented femoral piece was stable, with no lucent line and in position since the initial implantation. The reoperation consisted in cementing a new polyethylene cup (< 32 mm) with or without a graft. The femoral head was initially ceramic (alumina 29 and zircon 25) and was preserved in ten cases (alumina) and changed systematically for the zircon heads. New heads were implanted: 20 alumina (32mm) and 24 metal. Calcar osteolysis was measured in mm² on the x-rays before and after changing the acetabular piece and then regularly every year to last follow-up (10 to 20 years).

Results: Preoperatively, superior femoral osteolysis was 156 mm² (48–576m²) situated in Guren zone 1 and 7. At last follow-up, it was 135 mm² (38–616 mm²) with no femoral loosening, decreased in 34 cases, unchanged in 11 and increased in 9. Spontaneous decline in preoperative osteolysis was observed when the bearing was alumina-polyethylne and the preoperative osteolysis was less than 100 mm². Increased osteolysis (minor but undeniable) was observed with the couple was metal-polyethylene and when the preoperative osteolysis was > 300 mm².

Discussion: If the superior femoral osteolysis does not compromise the stability of the femoral implant when undertaking isolated revision of the acetabular component alone, it can be neglected. Changing the bearing stabilizes the progression of the osteolysis and does not appear to compromise the mid-term outcome (15 years) for the femoral piece. Spontaneous decline of the osteolysis can be observed if the initial osteolysis is less than 1 cm² and if the new bearing is alumina-polyethylene.

Purpose of the study: In vivo kinematics of the knee joint (anteroposterior translation or rollback, axial rotation, elevation of the femoral condyle, range of motion) was determined for the knees of 30 subjects with a total knee prosthesis with a fixed or mobile plateau and also for the normal knees.

Material and methods: Videofluoroscopic images were recorded during gait and maximal flexion. An automatic 3D adaptation-modelling process was then applied to the fluoroscopic images to determine knee kinematics.

Results: For the normal knee, a certain degree of femoral rollback was noted for the lateral compartment (4.2 mm on average) while minimal translation was observed medially. The femoral rollback increased laterally during maximal flexion (14.4 mm on average) while the medial translation was minimal (1.5 mm on average). Thus, the average movement, which was not observed for all normal knees tested, was a pivot movement centred medially. The variability observed during maximal flexion was wide for all knee prostheses with a fixed or mobile plateau which do not have a stabilising system substituting for the absent posterior cruciate. During flexion, the normal knees exhibited mean 10° external rotation of the over the tibia. All of the rotational knee prostheses presented external rotation (mean 5°, ragne 0–10°). Inversely, the posterostabilised prostheses exhibited medial rotation of the femur over the tibia (mean 5°, range 0–10°), i.e. paradoxical movement.

Discussion: Unlike the normal knee where femoral rollback occurs during maximal flexion, paradoxical anterior translation of the femorotibial point of contact after arthroplasty, in particular in subjects with a fixed plateau prosthesis. For prostheses substituting for the posterior cruciate, femoral rollback involving the lateral condyle occurs regularly with minimal variability in the femorotibial contact point due to the regular engagement of the cam and cam follower mechanism during maximal flexion.

Purpose of the study: The alumina-polyethylene bearing has been used for many years but no study has evaluated polyethylene wear and osteolysis with a 32 mm head with a follow-up exceeding 20 years.

Material and methods: Thirty-six arthroplasties implanted between 1983 and 1985 (26 patients, mean age 54 years, range 35–65 years) were studied. The same cemented implants were used in all cases, with no loosening. Penetration of the head into the polyethylene was measured annually on digital radiographs and with computer assistance. Osteolysis was quantified in mm² on the merckel.

Results: At 20 years follow-up (minimum) or more, penetration of the femoral head into the cup was on average 0.07mm/y. The characteristic feature of the wear curve was the perfect stability after the third year and the absence of any increase over time. Extrapolation of the straight part of the curve to the origin determined the creep. True wear was limited: 0.05mm/y. It was not modified by the polyethylene thickness (eight 52mm cups, twenty-three 50mm and five 48mm). Corresponding volumetric wear was estimated at 640 mm3 at maximum follow-up. At last follow-up, osteolysis measured in mm² on the meckel was 65 mm² on average. In general, this osteolysis appeared around the second year with an imprint on the merckel; it then increased linearly and regularly to the 20th year. Acetabular osteolysis was nevertheless greater than that observed with the Al/Al bearing of controlateral hips implanted at the same period when evaluated on the scan for both hips (20 cases).

Discussion: The alumina-polyethylene bearing enables long implant survival for at least 20 years, even for relatively thin polyethylene thicknesses. The characteristic feature of the bearing is the linear polyethylene wear which does not increase with time but remains constant, undoubtedly in relation to the absence of any change in the roughness of the head despite the very long follow-up. Osteolysis remains minimal, but superior to that observed with Al/Al bearings implanted during the same period in controlateral hips.

From a theoritical point of vue, experience is an important factor in obtaining a satisfactory result in arthroplasty surgery. We wished to determine whether standard posterior stabilized total knee replacement (PS TKA) performed by young surgeons (Group A) increased rates of mortality and complications compared with PS TKA performed by senior surgeons (Group B) using the same model of arthroplasty. Between 1990 and 1995, 195 patients underwent 250 total knee arthroplasties in the same orthopaedic university department of the hospital by two senior surgeons (100 TKA; Group B) and 12 younger surgeons without senior assistance (150 TKA; Group A). The procedures were undertaken consecutively and the implant was always the same.

There were no significant pre-operative differences between the groups in terms of age, gender, height, weight, body mass index, diagnosis, comorbidity and duration of follow-up, which was more than 15 years in both groups. Pre-and postoperative assessments were made according to the system of the Knee Society. The preoperative and postoperative deformities were measured on weight-bearing radiographs of the whole limb (hip-knee-ankle angle).

The mean Knee Society knee and functional scores were not significantly different (p = 0.125) pre-operatively: 37.5 points (16 to 53) and 15 points (0 to 20) respectively in the Group B, and 36.0 points (10 to 58) and 17 points (0 to 30) respectively in the Group A; and at final follow-up (p = 0.145): 91 points (42 to 100) and 82 points (25 to 100) respectively in the Group B, and 89 points (58 to 100) and 84 points (35 to 100) respectively in the Group A.

The rate of survival at ten years, with revision as the endpoint for failure, was 96% (95% CI, 93 to 100) in both groups; at fifteen years 91% (95% CI, 85 to 97) in group B, and 92% (95% CI, 90 to 94) in group A. There were no significant differences in revision rates in Group B or Group A (p = 0.735). In the Group B group, 1 knee (0.6%) revised for osteolysis, 1 (0.6%) deep infection, 1 (0.6%) aseptic loosening, and 1 (0.6%) for fracture. In the Group A, 1 knee (1%) revised for deep infection, none for osteolysis and 2 (2%) for aseptic loosening, and one for dislocation.

In this series surgeons in the early stages of their careers achieved the same results as seniors; so this study is very reassuring for patients undergoing surgery in a university hospital. Our study has however limitations. All the patients received cemented TKA in a large-volume centre specialising in joint reconstruction. It is not a randomised-controlled trial; but it would be impossible to perform one. Would really patients sign up to a study where they would be randomised between an inexperienced and experienced surgeon? What is difficult to assess is how the ‘learning curve’ of one implant affects the ‘learning curve’ for a different implant.

Introduction: This study evaluated the creep and true wear in 55 medial and in 35 lateral fixed bearing uni-compartmental implants that had a flat articular surface at the time of implantation.

Materials and Methods: All the polyethylene components had the same design, the same sterilization, and were retrieved from 11 to 244 months after their implantation. The postoperative deformity had been measured on weight-bearing radiographs of the whole limb (hip-knee-ankle angle). The retrieved implants were placed in a coordinate measuring machine.Using this system, a three dimensional scaled image was used to calculate the total penetration of the femoral implant in relation with true wear and creep. To separate plastic deformation from true wear, the volume of true wear was calculated by wheighing the tibial components and comparing the results with non implanted components. Difference between the penetration determined by the coordinate machine and penetration determined by wheighing was considered to be in relation with creep.

Results: Total linear penetration rates ranged from 0.2 to 2.6 mm/year (mean 0.19 mm/year) and was significantly less in lateral (mean 0.14 mm/year) than in medial implants (mean 0.25 mm/year). Linear penetration rates in relation with wear ranged from 0.1 to 1.4 mm/year (mean 0.13 mm/year), and penetration in relation with creep ranged from 0.1 to 1.9 mm/year (mean 0.12 mm/year). The linear penetration of the femoral condyle in relation with true wear was negatively correlated with length implantation in both medial and lateral implants. The linear penetration in relation with creep was higher in the first two years after the implantation versus the subsequent years in both medial and lateral implants. Using multiple linear regression analyses to remove the confounding effects of age, weight, gender and thickness of the implant, we found that an increase of the postoperative deformity was in relation (p = 0.03) with an increase of creep and an increase of true wear for medial implants. But an increase of the postoperative deformity was not in relation (p = 0.34) with an increase of creep or an increase of true wear for lateral implants.

Discussion: the postoperative deformity has a high influence on the penetration rate of the femoral condyle in the polyethylene of medial unicompartmental fixed bearing tibial implants. This phenomenon was not observed for the lateral fixed bearing implants and wear was significantly (p= 0.01) less in lateral than in medial implants. This phenomenon (important for the surgical technique and the choice of implant designs) may be in relation with different kinematics in the two compartments.

Maltracking or subluxation is one of the complication of patellofemoral arthroplasty (PFA). The purpose of this investigation was to measure femoral component rotational alignment in PFA using a standard computed tomography (CT) scanner. Second, apply this technique to two groups; a control group of patients with well functioning PFA and a study of a group of patients with patellofemoral problems as maltracking or subluxation.

Data was analyzed from our center that has continuously performed PFA for isolated patellofemoral degenerative disease since 1978. Patients were included if they had a minimum four year follow up. A total of 124 patients (149 knees) were treated with PFA. There were 39 men and 85 women who had a mean age of 64 years (range, 46 to 78 years). A pre-operative and post-operative CT scan is performed in our center for all the patients since this period to assess femoro-patellar malalignment. The trochlear twist angle was determined using the single axial CT image through the femoral epi-condyles. To determine whether the femoral component was in excessive internal or external rotation, measurements were done on the post-operative CT scan and the trochlear twist angle of the femoral component was compared to the pre-operative trochlear twist angle.

At a mean follow up of 13 years (range, 4 to 30 years), overall prosthetic survival and preservation was 91 per cent. There were 112 knees (75 per cent) with good or excellent clinical results (Knee Society score of 80 points or more). Revision to total knee replacement for femoro-tibial disease progression was necessary in 9 knees (6 per cent). Complications related to the patellofemoral arthroplasty (28 knees) included : residual pain or mechanical symptom 10 (7 per cent) requiring other ancillary procedures ; maltracking or subluxation 18 (12%) with component revision in 10 knees; Radiographic findings show 2 component loosenings and 1 patella fracture. There was no incidence of infection or component wear.

The group with patellofemoral complications had excessive (p less than 0.01) femoral internal component rotation. This excessive combined internal rotation was directly proportional to the severity of the patellofemoral complication. Small amounts of internal rotation (1–4 degrees) correlated with pain. Moderate combined internal rotation (5–10 degrees) with lateral tracking and patellar tilting. Large amounts of combined internal rotational (10–17 degrees) correlated with patellar sub-luxation, early patellar dislocation or late patellar prosthesis failure (fracture of the patella or loosening of the patella button). The control group (112 knees without complications) was in external rotation (10-0 degrees).

This study showed that increasing amounts of excessive internal rotational malalignment resulted in more severe patellofemoral complications.

Purpose of the study: Perception of leg length discrepancy after total hip arthroplasty (THA) is a source of patient dissatisfaction. We followed 100 patients with firstintention THA to determine the clinical significance of radiological leg length discrepancy of less than 15 mm.

Materials and Methods: An investigator blinded to the clinical context measured radiological leg length discrepancy in 100 patients after THA. Another investigator evaluated the clinical perception of leg length discrepancy in the same patients 15 days, one month, three months and one year after implantation of their THA.

Results: At 15 days, 73 patients had a clinical perception of leg length discrepancy; 48 at one month; 24 at three months; and 15 at one year. Although the 15 patients (15%) presented leg length discrepancy greater than 10 mm (but less than 15 mm), only four still perceived this difference at one year. At one year, there was no correlation between the length of the discrepancy and clinical perception by the patient. When patients had a length discrepancy greater than 10 mm (but less than 15 mm), the probability of perceiving the difference clinically was not greater (p> 0.05) than for patients whose leg length discrepancy was less than 10 mm. Conversely, patients who perceived a leg length discrepancy at one year had significantly more pronounced (p=0.02) spinal disorders and more permanent hip flexion.

Discussion: Perception of leg length discrepancy is a frequent complaint postoperatively, but rare at one year, even when the radiological difference reaches 15 mm. At one year, the perception of leg length discrepancy is not correlated with the radiological difference but rather with the degree of spinal disorder or permanent hip flexion.

Conclusion: Navigation would have a modest effect on this problem which is probably related in part to spinal rehabilitation.

Severe acute respiratory syndrome (SARS) is a newly described infectious disease caused by the SARS coronavirus which attacks the immune system and pulmonary epithelium. It is treated with regular high doses of corticosteroids. Our aim was to determine the relationship between the dosage of steroids and the number and distribution of osteonecrotic lesions in patients treated with steroids during the SARS epidemic in Beijing, China in 2003.

We identified 114 patients for inclusion in the study. Of these, 43 with osteonecrosis received a significantly higher cumulative and peak methylprednisolone-equivalent dose than 71 patients with no osteonecrosis identified by MRI. We confirmed that the number of osteonecrotic lesions was directly related to the dosage of steroids and that a very high dose, a peak dose of more than 200 mg or a cumulative methylprednisolone-equivalent dose of more than 4000 mg, is a significant risk factor for multifocal osteonecrosis with both epiphyseal and diaphyseal lesions. Patients with diaphyseal osteonecrosis received a significantly higher cumulative methylprednisolone-equivalent dose than those with epiphyseal osteonecrosis. Multifocal osteonecrosis should be suspected if a patient is diagnosed with osteonecrosis in the shaft of a long bone.

Purpose of the study: This retrospective analysis compared surgical treatments of femoral neck fractures in patients aged over 80 years.

Material and methods: Two hundred femoral neck fractures (Garden 3 and 4) were treated in three different manners: total prosthesis with a retaining cup (74 patients), intermediary prosthesis (58 patients), and osteosynthesis (68 patients). Indications were the same, but the periods of treatment were successive. Study variables were: mortality, number of revisions, duration of hospital stay, discharge to home or rehabilitation center, cost per hospital day. Follow-up was at least two years. The chi-square test was applied with p< 0.05.

Results: Mortality was similar for the three groups: eight deaths during stay in orthopedic unit (4%), three after total prosthesis (4%), three after osteosynthesis (5%) and two after intermediary prosthesis (3%). The difference was nonsignificant (p=0.24). Among the total prostheses, five dislocations (6.7%) required anesthesia despite the retaining cup. The rate of dislocation was 12% for intermediary prostheses and to avoid recurrence four revisions were needed to totalize an intermediary prosthesis with a retaining cup. Among the osteosynthesis cases, the rate of revision was 25%; transformation to a total prosthesis was necessary for 17% and material removal with resection of the head and neck was necessary in 8%. One total prosthesis and one intermediary prosthesis had to be removed because of infection. Resection of the head and neck for infection also occurred in one patient with an intermediary prosthesis. The rate of revision for an orthopedic problem was significantly less (p< 0.01) in the total prosthesis group. At last follow-up, or before death, patients with a total prosthesis were more independent and returned to their home significantly more often than patients treated with osteosynthesis. The economic cost of these interventions were not significantly different, the cost of the implant being insignificant compared with the cost of hospitalization and reeducation of this very elderly population.

Discussion: Total hip arthroplasty is a recognized treatment for painful degenerative hip disease. Historically, the total prosthesis was not considered as a first-intention treatment for fractures of the femoral neck in elderly subjects due to the risk of intraoperative blood loss, the risk of infection, and the risk of dislocation if a hip stabilization mechanism was not applied. This study demonstrated that, in light of the complications observed with the other methods, progress in anesthesia and use of implants avoiding dislocation can be proposed as first-intention treatment for total prosthesis patients who suffer a fracture of the femoral neck.

Purpose of the study: The aim of this study was to analyze rotation of the normal and prosthetic distal femur as well as the spaces from 90 to 130 degrees flexion.

Material and methods: Torsion scans were obtained preoperatively and postoperatively for 44 total knee prostheses. The difference in femoral torsion between the pre- and postoperative image was used to assess the rotation in which the femoral component was implanted. The prostheses were divided into two groups: group I when the femoral implant was implanted with external rotation of more than 5°; group II when the femoral implant was implanted with external rotation less than 5°. A preoperative stress scan was obtained in 20 patients then repeated during the year following implantation. Stress images with knee flexion at angles from 90° to 130° were obtained. The patient was installed in the ventral supine position. 8mm scan slices were centered on the lower end of the femur, ten 50ms images were acquired during flexion movement from 90° to 130°. This enabled determination of the knee flexion axis preoperatively and postoperatively, to measure the variation in the epicondylar axis compared with the mechanical axis of the tibia between 90° and 130° flexion and finally to deduct change in the femorotibial space in flexion from 90° to 130°.

Results: The 18 total knee prostheses with a femoral component implanted with external rotation greater than 5° (group I) showed significantly greater range of flexion (p< 0.05) (mean 120°, range 110°–130°) than the 26 prostheses in group II with a femoral component implanted in external rotation less than 5° (mean 100°, range 80°–115°. For the 20 knees with stress scans, the preoperative images showed an epicondylar axis about 5° fro the mechanical axis of the tibia when the knee flexed in the 90°–130° range. After surgery, the stress scans showed that this epicondylar axis of rotation of the prosthesis-bearing knees occurred especially for knees with a wide range of flexion. The 20 knees with flexion limited to 100° did not present an epicondylar rotation axis compared with the mechanical axis of the tibia. The 15 knees with 125° flexion or more had an epicondylar axis of rotation after 90° flexion. Rotation of the epicondylar axis in relation to the mechanical axis of the tibia between 90° and 130° flexion was the consequence of a femorotibial space which changed in the medial and laeral femorotibial compartments between 90° and 130° flexion: after 90° flexion, the medial femorotibial space decreased and the lateral femorotibial space increased. This explains why movement from 90° flexion to 130° flexion was facilitated by placing the femoral piece in external rotation.

Discussion: Search for ligament balance for knee flexion above 90° is logical only if the goal is to obtain knee stability in extension and flexion at 90°. It is probably no rational if the goal is to allow the knee to reach flexion in the 120°–130° range. Ligament balance in flexion above 90° is important and should be maintained up through 130° flexion. The other solution is to empirically increase external rotation of the femoral component a few degrees in order to allow greater range of flexion.

Purpose of the study: The humeral head is the second most frequent localization of non-traumatic osteonecrosis. For certain etiologies, for example sickle-cell anemia, the frequency is similar to that observed for the femoral head. There have nevertheless been very few publications on this pathology and its treatment. The purpose of this study was to assess outcome in a series of 771 cases of humeral head osteonecrosis in order to establish the natural history of the disease, criteria predictive of outcome, and therapeutic options.

Material and methods: The diagnosis of osteonecrosis of the humeral head was established for 771 humeri in 424 patients between 1981 to 2000. Minimum follow-up was five years (maximum 23 and mean 13 years). Outcome was assessed in terms of the clinical course, specifically the need for surgery due to pain or functional impotency. The radiological assessment was made on serial AP and lateral views taken every year or two years. The extent of the osteonecrosis was assessed on the basis of the magnetic resonance imaging (MRI) findings when available (after 1985). The ARlet and Ficat classification established for the femoral head was adapted to the shoulder: grade I: osteonecrosis of the humeral head visualized solely with MRI; grade II: radiologically detectable osteonecrosis; grade III: subchondral dissection without loss of spherical shape: grade IV: loss of spherical shape without visible osteoarthritis: grade V: osteoarthritis.

Results: Bilateral osteonecrosis was observed in 82% of the 424 patients. This gave 771 cases of humeral head necrosis. There was no gender predominance. Mean age at diagnosis was 32 years (range 18–57 years). The most frequent etiology was sickle-cell anemia (307 patients), followed by corticosteroid therapy (80 patients). Other etiologies were much less frequent: alcohol abuse, Gaucher’s disease, hyperlipidemia. Osteonecrosis of the humeral head was generally associated with another localization, particularly involving the hip and the knee joints. Multifocal osteonecrosis was also a common finding. Among the patients whose dignosis of osteonecrosis was established before symptom onset (scintigraphy or MRI performed in patients with multifocal osteonecrosis), the natural history was on average three years between MRI diagnosis and onset of pain. For 46% of the cases, pain appeared at grade I, before the development of radiographic signs. In 54% of the cases, grade II occurred before pain. It took six years before all of the cases with osteonecrosis diagnosed in a non-symptomatic phase produced pain. Factors affecting the rapidity of the radiological course were: etiology, size of the necrotic focus, presence and rapidity of osteonecrosis in other localizations (hip and knee). The humeral head lost its spherical shape on average four to five years after the diagnosis of osteoarthritic degradation of the joint, at about seven to eight years of evolution. Among the 256 patients followed for more than ten years, 51% required surgery. These 131 operations were for: drilling with bone marrow grafting (grade I or II) (n=62), cimentoplasty after loss of spherical shape but before glenohumeral osteoarthritis (n=15), resection of sequestered necrosis after loss of spherical shape (n=12), shoulder arthroplasty (n=42).

Discussion and conclusion: This study demonstrated that the natural history of osteonecrosis of the humeral head has a poor long-term outcome. Shoulder arthroplasty is rarely required during the first decade of the disease. Other therapeutic alternatives can help avoid or retard the need for shoulder arthroplasty in these very young patients.