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Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IV | Pages 136 - 136
1 Mar 2012
Sivardeen Z Bisbinas I De Silva U Green M Grimer R Learmonth D
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Pigmented villonodular synovitis is a monoarticular proliferative process most commonly involving the synovium of the knee joint. There is considerable debate with regards to diagnosis and effective treatment.

We present our experience of managing PVNS of the knee joint over a 12 year period. Twenty-eight patients were reviewed. MRI was used to establish recurrence in symptomatic patients rather than routine screening and to identify posterior disease prior to surgery.

Eight patients had localised disease and were all treated with open synovectomy and excision of the lesion, with no evidence of recurrence. Twenty patients had diffuse disease, eight treated arthroscopically and twelve with open total synovectomy. Nineteen patients (95%) had recurrence on MRI, however, only five (25%) had evidence of clinical recurrence.

There were no significant complications following arthroscopic synovectomy. Open synovectomy, in contrast, was associated with three wound infections and two thrombo-embolisms. Three patients had Complex regional pain syndrome.

We believe diffuse disease should be treated with arthroscopic synovectomy which is associated with minimal morbidity and can be repeated to maintain disease control. Radiotherapy is helpful in very aggressive cases. TKR was used when there was associated articular erosion.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_I | Pages 35 - 35
1 Jan 2011
Mohammed R Unnithan A Kaustubh D Bansal M Jimulia T Green M Learmonth D
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The results of a multi-surgeon, multi-implant series of patellofemoral joint arthroplasty performed over a ten year period are presented. All patellofemoral joint arthroplasty performed from the years 1996 to 2006 were retrospectively reviewed using case notes, radiographs and clinic appointments until their latest follow-up period.

101 arthroplasties in 91 patients were followed up for average period of 48 months (range 6–96 months). The average age was 57 years with female patients thrice as common as male patients. There were 5 (5%) complications with 1 deep infection and 4 stiff knees. 35 subsequent procedures were performed in 28 patients including arthroscopic debridement in 18, arthroscopic lateral retinacular release in 8, tibial tuberosity transfer in 3, manipulation for stiffness in 2, and revision to total knee arthroplasty in 4 patients (3 for progression of tib-iofemoral osteoarthritis and 1 for infection).

The necessity of further surgeries in one third of the study group suggests that close follow-up of these patients is needed to address any concerns that can be easily resolved.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 36 - 36
1 Mar 2010
Mohammed R Unnithan A Durve K Bansal M Jimulia T Green M Learmonth D
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Purpose: Isolated patellofemoral joint (PFJ) osteoarthritis has long been a common observation as an important source of knee pain. Once non-operative treatment modalities have been exhausted, the surgical options available are transposition/elevation of tibial tubercle, drilling, realignment procedures, patellectomy, patellar resurfacing, patellofemoral arthroplasty (PFA) and total knee arthroplasty (TKA). Among these, PFA is an established treatment of isolated PFJ osteoarthritis. We present our multi-surgeon, multi-implant series of patellofemoral joint arthroplasty performed over a 10 year period.

Method: This study was a retrospective review of all PFA performed in the Knee Arthroplasty Unit at our hospital over a ten year period from 1997 to 2006. The unit comprises seven specialist surgeons, each with considerable experience in knee arthroplasty and numerous trainee surgeons. One hundred and one PFA performed in 91 patients were identified from the theatre records. Three different implant models were used: the Lubinus implant (Waldemar Link), the FPV system (Wright Medical) and the Avon system (Stryker Howmedica Osteonics).

Results: 101 arthroplasties in 91 patients were followed up for average period of 48.8 months (6–96 months). Of these, none were lost to follow up. The average age was 57 years with female patients thrice as common as male patients. Concomitant procedures in the form of 23 lateral retinacular release or 6 osteochondral autograft transfer system (OATS) were performed. There were 6 complications with 2 infections and 4 stiff knees. 31 arthroplasties had subsequent procedures including arthroscopic debridement (18), arthroscopic lateral retinacular release (8), tibial tuberosity transfer (3) and manipulation for stiffness (2). A total of 4 arthroplasties underwent revision to total knee arthroplasty, 2 for infection and 2 for progression of tibiofemoral osteoarthritis.

Conclusion: The necessity of revision surgeries in one third of the cases suggests that close follow-up of the patients is needed to address any concerns that can be easily resolved. A majority of the patients in our study had very good outcomes and did not need subsequent procedures in the medium term. Our study reiterates the importance of proper patient selection, surgeon experience and correct surgical technique in successful outcomes from PFA.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 350 - 350
1 Jul 2008
Sivardeen K Green M Massoud S Learmonth D
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Background – Frozen Shoulder is a common condition which causes significant morbidity in people of working age. The 2 most popular forms of surgical treatment for this condition are Manipulation under Anaesthesia (MUA) or MUA plus Arthroscopic Capsular Release (ACR). Both treatment modalities are known to give good results, but no-one has compared the 2 to see which is better.

Aim – To compare the outcome in patients with primary frozen shoulder, who are treated by either MUA or MUA plus ACR.

Method – 61 patients with primary frozen shoulder were treated by either MUA or MUA plus ACR. Each patient had their American Shoulder and Elbow Score (ASES), and their Oxford Shoulder Score (OSS) measured pre and post-operatively.

Results – The patients who had MUA plus ACR had a mean ASES of 24.8 preoperatively, 64 at 4 months, and a mean of 75.4 at 12 months. The mean OSS was 32.5 pre-operatively, 48.5 at 4 months and 53.4 at 12months. The patients who had a MUA had a mean ASES of 28.7 pre-operatively, 60.9 at 4months and 69.6 at 12months. The mean OSS was 33 preoperatively, 46.5 at 4 months and 50.9 at 12 months.

Conclusions – Both treatments give good results. MUA plus ACR give superior numerical results at 6 to 12 months post-operatively, however, these figures did not reach statistical significance


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 360 - 360
1 Jul 2008
Sivardeen K Green M Massoud S Learmonth D
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The aim of this study was to review the results of surgery on patients who had recurrent instabilty of the shoulder associated with significant bone loss who were treated by autogenous iliac crest tricortical grafts. Ten consecutive patients were reviewed. All had significant loss of glenoid bone stock as assessed by CT scan. All were treated by use of tricortical bone graft harvested from the iliac crest and fashioned to reconstitute the anterior glenoid defect. This was fixed intra-articularly with cannulated screws. The antero-inferior capsule was then repaired to this new “glenoid rim”. All patients had a standard rehabilitation regime. All patients had an assessment of the Oxford Shoulder Instability Score (OIS) and the American Shoulder and Elbow Surgeons Score (ASES) before and after the operation. At an average follow-up of 26 months, the mean OIS had improved from 38.3 to 22.3 and the mean ASES had increased from 40.5 to 86.6. None had had a recurrent dislocation. The use of autogenous iliac crest bone graft to treat recurrent shoulder instability associated with significant glenoid bone loss is an effective treatment for this difficult condition.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 115 - 115
1 Mar 2006
Karataglis D Green M Learmonth D
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Full-thickness chondral defects of weight-bearing articular surfaces of the knee are a difficult condition to treat. Our aim is to evaluate the mid- and long-term functional outcome of the treatment of osteochondral defects of the knee with autologous osteochondral transplantation with the OATS technique.

Thirty-six patients (37 procedures) were included in this study. Twenty-three patients were male and 13 female with a mean age of 31,9 years (range: 18 to 48 years). The cause of the defect was OCD in 10 cases, AVN in 2, lateral patellar maltracking in 7, while in the remaining 17 patients the defect was post-traumatic. The lesion was located on the femoral condyles in 26 cases and the patellofemoral joint in the remaining 11. The average area covered was 2,73cm2 (range: 0,8 to 12cm2) and patients were followed for an average of 36,9 months (range: 18–73 months).

The average score in their Tegner Activity Scale was 3,76 (range: 1–8), while their score in Activities of Daily Living Scale of the Knee Outcome Survey ranged from 18 to 98 with an average of 72,3. Thirty-two out of 37 patients (86,5%) reported improvement of their pre-operative symptoms. All but 5 patients returned to their previous occupation while 18 went back to sports. No correlation was found between patient age at operation, the size or site of the chondral lesion and the functional outcome.

We believe that autologous osteochondral grafting with the OATS technique is a safe and successful treatment option for focal osteochondral defects of the knee. It offers a very satisfactory functional outcome and does not compromise in any way patients’ future options.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 109 - 109
1 Mar 2006
Karataglis D Green M Learmonth D
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Patellofemoral problems are probably the most common type of knee complaint in adolescents and adults. Our aim is to evaluate the mid- and long-term functional outcome, as well as to detect factors affecting it in patients who underwent a modified Elmslie-Trillat procedure.

Forty-two patients (49 procedures) were included in this study. Nine were male and the 33 female, with a mean age of 31,3 years (range: 19 to 56). The reason for operation was patellar instability (recurrent subluxation or dislocation) in 13 cases (26,5%), anterior knee pain with malalignment of the extensor mechanism in 17 cases (34,7%) and a combination of both in the remaining 19 cases (38,8%). Patients were followed for a minimum of 18 months and an average of 38,6 months (range: 18 to 130 months).

The functional outcome according to Cox’s criteria was excellent in 14 cases (28,6%), good in 20 cases (40,8%), fair in 9 cases (18,4%) and poor in the remaining 6 cases (12,2%). Patients scored an average of 3,57 (range: 2–8) in their Tegner Activity Scale, while their score in Activities of Daily Living Scale of the Knee Outcome Survey ranged from 43 to 98 (average: 75,8). Result analysis revealed that the functional outcome was better in the subgroup that had the procedure due to patellar instability. Furthermore, the outcome was significantly better in the absence of grade 3 or 4 chondral changes in the patellofemoral joint at the time of operation (t-test: p=0,0362).

Elmslie-Trillat procedure satisfactorily restores patellofemoral stability and offers a very good functional outcome, especially in the absence of significant chondral changes in the patellofemoral joint at the time of operation.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 150 - 150
1 Apr 2005
Karataglis D Bisbinas I Green M Learmonth D
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Multiple ligament deficiency in knees is usually the aftermath of high velocity trauma and leads to complex multidirectional instability, that can in turn greatly compromise the patient’s functional level if left untreated. The aim of this study is to evaluate the mid- and long-term functional outcome of patients who underwent complex reconstruction for multiple ligament deficiency.

Twenty-nine patients (21 male and 8 female) with an average age of 35.54 years (range 17–60) underwent arthroscopic or arthroscopically assisted multiple ligament reconstruction at an average of 2.1 years following their initial knee injury. Thirteen of them sustained a multiple ligament injury following an RTA, 11 during sports and 5 following a fall from a height.

They were followed for a period of 13 to 108 months (average: 45.8) and functionally evaluated according to Clancy’s criteria. The functional outcome was excellent in five patients (17.2%), good in ten (34.5%), fair in twelve (41.4%), while two reconstructions resulted in a failure (6.9%). Eleven patients returned to sporting activities and all but three returned to work, although sometimes in lighter duties.

Arthroscopic multiple ligament reconstruction is a complex and technically demanding procedure that should be carried out in specialised units. Although it rarely results in a “normal” knee, it offers in most cases a stable as well as functional knee.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_I | Pages 97 - 97
1 Jan 2004
Bisbinas I Mirza A Green M Learmonth D
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Rotator cuff pathology is common in orthopaedic patients. However, there are still debates about the best way of treating those patients. We present the clinical experience from our Unit.

We present 85 patients who had arthroscopic or arthroscopically assisted shoulder surgery for full thickness rotator cuff tears between 1994 and 2001. Their medical records and radiological investigations were reviewed, and the management as well as the outcome of their treatment were recorded. The aim was to review those patients and determine if optimum assessment and management was implemented to them.

There were 47 male and 38 female patients with average age 58.8 years and weight 79.9 kg, 32 of the patients reported trauma prior to their symptoms. 63 patients had MRI scan and they had average 2.6 years of symptoms and 2.4 steroid injections before their operative management. 27 patients had arthroscopic and 58 mini open rotator cuff repair. From those with recorded pain management 32 patients had interscalene block and 21 infiltration with local anaesthetic. Their average hospital stay was 1.4 and 1.8 days for the arthroscopic and mini open repairs respectively. In 69 (77.7%) patients the result was considered overall satisfactory; 8 (9.4%) patients had temporary shoulder stiffness and/or pain, which were treated conservatively with steroid injections and physiotherapy. 11 (12.9%) of the patients required reoperation, 5 from which required cuff resuturing and 4 manipulations under anaesthetic for postoperative stiffness. 3 patients (3.5%) had other than shoulder complications including CVA, chest infection, and CTS.

Rotator cuff surgery remains a challenge where often the working surgical plan is altered intraoperatively and tissue quality is of major importance for the final outcome. Arthroscopy has reduced patient’s hospital stay and rehabilitation time. However, a not durable repair, or postoperative stiffness can be a potential risk complicating the surgical result.

In this study it is demonstrated that treatment of patients with rotator cuff disease is still a challenge, time in hospital is reduced with arthroscopic management, but the overall risk for reoperation/MUA either for not durable previous repair or postoperative stiffness was still quite high (12.9%).


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_I | Pages 97 - 97
1 Jan 2004
Bisbinas I Mirza A Green M Learmonth D
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Rotator cuff or long head of biceps tendon tears are common in patients with degenerative shoulder rotator cuff disease. Most often they are investigated with an MRI scan. Diagnosis prior to surgery is useful for the appropriate surgical planning.

We present 63 consecutive patients who had arthroscopic shoulder surgery and prior to that had MRI investigation between 1994 and 2001. Their medical records were reviewed; arthroscopic operative findings as well as the report of the MRI scan were recorded and compared retrospectively. The aim of our study was to assess the accuracy of MRI findings comparing the arthroscopic ones regarding rotator cuff and biceps tendon pathology.

There were 63 patients with mean age 58 years. All of these had MRI scan investigation and the waiting time prior to surgery was 10 months. It was found that there were 6 false (−)ve, 1 false (+)ve and two cases with full thickness cuff tears which were reported as probable tears. Further to that, there were 11 frayed biceps tendons, 8 partially ruptured, 3 subluxed, 4 complete ruptures and 1 SLAP lesion. All biceps lesions were not commented in the MRI scan reports.

MRI scan is very sensitive detecting soft tissue pathology in shoulder investigation. However, even on that basis, rotator cuff and in particular biceps tendon pathology can be missed. The shoulder arthroscopy is the best method to accurately diagnose those lesions. However, it should be noted that often the surgeon has got to alter to working surgical plan in order to address the problem intraoperatively.

In this study it is demonstrated the MRI scan often misses rotator cuff or long head of biceps tendon pathology. The most sensitive method for the diagnosis of it is the shoulder arthroscopy, which address its treatment in the same time.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_II | Pages 168 - 168
1 Jul 2002
Pimpalnerkar A Myers G Van Dellen D Green M Learmonth D
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Full thickness defects of articular cartilage have a poor capacity for biological repair and often progress to osteoarthritis. Various surgical techniques have been developed to overcome the inability of chondrocytes to heal injured cartilage. Arthroscopic lavage and debridement offer temporary symptomatic relief whereas marrow-stimulating techniques like drilling, microfracture and abrasion arthroplasty yield poor quality fibro-cartilage that is incapable of withstanding the mechanical stresses to which healthy articular cartilage is subjected.

We present our experience using the osteochondral graft transfer technique in the treatment of isolated Outerbridge grade 4 lesions of the knee. The study includes nineteen patients with a mean age of 29 years (range 17 to 40) presenting with symptomatic lesions of the knee with a mean defect size of 2.4cm (0.8 to 6). At a mean follow-up of 20 months (6 to 40) our results showed a significant improvement in patient function by a mean of 46 points or a 23% mean improvement as assessed by the Knee Society Score (P< 0.0001; One sample t-test). Similarly there was significant improvement in the Brittberg scores with a mean improvement by 2 clinical grades (p< 0.0001; Wilcoxon Rank test). Quality of life scores as measured by the Short Form 36 were dramatically improved by a mean of 24 points (p< 0.0001; Wilcoxon Rank test). In addition, there was significant reduction in pain post-operatively (p< 0.0001; Wilcoxon Rank test) with patients describing a mean improvement of 6 points as measured on the visual analogue chart. A significant number of patients (84.2%) were able to return to active sporting levels by 6 months (p< 0.0001;McNemar Change test).

The results of the osteochondral graft transfer technique, at relatively short-term follow-up, are encouraging with a high percentage of subjective satisfaction. This procedure proved to be a reliable and valid solution for treating isolated osteochondral defects of the knee, providing functional and durable cartilage that is critical to joint function.


The Journal of Bone & Joint Surgery British Volume
Vol. 71-B, Issue 3 | Pages 509 - 513
1 May 1989
Mackie I Green M Clarke H Isaac D

Bone samples from the iliac crest of patients with no signs of bone disorder were treated with collagenase to remove the collagen component and so allow detailed observation of the mineral hydroxyapatite. Both polished and unpolished surfaces were studied in the scanning electron microscope and they showed that the mineral component of bone is composed of small rounded units about 10 nm across which are fused together to form larger spheroidal units roughly 100 nm in diameter. In the unpolished surfaces these 100 nm units are seen to aggregate to form columns approximately parallel to their neighbours and with numerous interconnections forming a continuous mineral phase. The polished sections also show the hydroxyapatite as a continuous phase of contiguous spheroids and the holes from which the collagen fibres were removed are clearly revealed. Lamellations in the surface are interpreted as resulting from adjacent layers of collagen fibres having orientations approximately perpendicular to each other.