Robotically-assisted unicondylar knee arthroplasty (UKA) is intended to improve the precision with which the components are implanted, but the impact of alignment using this technique on subsequent polyethylene surface damage has not been determined. Therefore, we examined retrieved ultra-high-molecular-weight polyethylene UKA tibial inserts from patients who had either robotic-assisted UKA or UKA performed using conventional manual techniques and compared differences in polyethylene damage with differences in implant component alignment between the two groups. We aimed to answer the following questions: (1) Does robotic guidance improve UKA component position compared to manually implanted UKA? (2) Is polyethylene damage or edge loading less severe in patients who had robotically aligned UKA components? (3) Is polyethylene damage or edge loading less severe in patients with properly aligned UKA components? We collected 13 medial compartment, non-conforming, fixed bearing, polyethylene tibial inserts that had been implanted using a passive robotic-arm system and 21 similarly designed medial inserts that had been manually implanted using a conventional surgical technique. Pre-revision radiographs were used to determine the coronal and sagittal alignment of the tibial components. Retrieval analysis of the tibial articular surfaces included damage mapping and 3D laser scanning to determine the extent of polyethylene damage and whether damage was consistent with edge loading of the surface by the opposing femoral component.Introduction
Methods
Cementless acetabular components are commonly used in primary and revision total hip arthroplasty, and most designs have been successful despite differences in the porous coating structure. Components with 2D titanium fiber mesh coating (FM) have demonstrated high survivorships up to 97% at 20 years1. 3D tantalum porous coatings (TPC) have been introduced in an attempt to improve osseointegration and therefore implant fixation. Animal models showed good results with this new material one year after implantation2, and clinical and radiographic studies have demonstrated satisfactory outcomes3. However, few retrieval studies exist evaluating in vivo bone ingrowth into TPC components in humans. We compared bone ingrowth between well-fixed FM and TPC retrieved acetabular shells using backscatter scanning electron microscopy (BSEM). 16 retrieved, well-fixed, porous coated acetabulum components, 8 FM matched to 8 TPC by gender, BMI and age, all revised for reasons other than loosening and infection, were identified from our retrieval archive (Fig. 1). The mean time in-situ was 42 months for TPC and 172 for FM components. Components were cleaned, dehydrated, and embedded in PMMA. They were then sectioned, polished, and examined using BSEM. Cross-sectional slices were analyzed for percent bone ingrowth and percent depth of bone ingrowth (Fig. 2). Analysis was done using manual segmentation and grayscale thresholding to calculate areas of bone, metal, and void space. Percent bone ingrowth was determined by assessing the area of bone compared to the void space that had potential for bone ingrowth.Introduction
Methods
Neutral mechanical alignment in TKA has been shown to be an important consideration for survivorship, wear, and aseptic loosening. However, native knee anatomy is described by a joint line in 3° of varus, 2–3° of mechanical distal femoral valgus, and 2–3° of proximal tibia varus. Described kinematic planning methods replicate native joint alignment in extension without changing tibiofemoral alignment, but do not account for native alignment through a range of motion. An asymmetric TKA femoral component with a thicker medial femoral condyle and posterior condylar internal rotation paired with an asymmetric polyethylene insert aligns the joint line in 3° of varus while maintaining distal femoral and proximal tibial cuts perpendicular to mechanical axis. The asymmetric components recreate an anatomic varus joint line while avoiding tibiofemoral malalignment or femoral component internal rotation, a risk factor for patellofemoral maltracking. The study seeks to determine how many patients would be candidates for a kinematically planned knee without violating the principle of a neutral mechanical axis (0° ± 3°). A cohort comprised of 55 consecutive preoperative THA patients with asymptomatic knees and 55 consecutive preoperative primary unilateral TKA patients underwent simultaneous biplanar radiographic imaging. Full length coronal images from the thoracolumbar junction to the ankles were measured by two independent observers for the following: mechanical tibiofemoral angle (mTFA), mechanical lateral distal femoral angle (mLDFA), and mechanical medial proximal tibial angle (mMPTA). Patients who met the following conditions: mTFA 0°±3°; mLDFA 87°±3°; and mMPTA 87°±3°, were considered candidates for TKA with an asymmetric implant that would achieve a kinematic joint line and neutral mechanical axis. Similarly, patients with the following conditions: mTFA 0°±3°; mLDFA 90°±3°; and mMPTA 90°±3°, were considered candidates for TKA with a symmetric implant that would achieve a kinematic joint line and neutral mechanical axis.Introduction
Methods
The longevity of total hip arthroplasty (THA) is dependent on acetabular component position. We measured the reliability and accuracy of a CT-based navigation system to achieve the intended acetabular component position and orientation using three dimensional imaging. The purpose of the current study was to determine if the CT-guided robotic navigation system could accurately achieve the desired acetabular component position (center of rotation (COR)) and orientation (inclination and anteversion). The postoperative orientation and location of the components was determined in 20 patients undergoing THA using CT images, the gold standard for acetabular component orientation. Twenty primary unilateral THA patients were enrolled in this IRB-approved, prospective cohort study to assess the accuracy of the robotic navigation system. Pre- and post-operative CT exams were obtained and aligned 3D segmented models were used to measure the difference in center of rotation and orientation (anteversion and inclination). Patients with pre-existing implants, posttraumatic arthritis, contralateral hip arthroplasty, septic arthritis, or previous hip fracture were excluded. All patients underwent unilateral THA using robotic arm CT-guided navigation (RIO Makoplasty; MAKO Surgical Corp).Introduction
Methods
Highly crosslinked ultrahigh-molecular-weight polyethylene (XLPE) reduces wear and osteolysis in total hip arthroplasty, but it is unclear if XLPE will provide the same clinical benefit in total knee arthroplasty (TKA). Adhesive and abrasive wear generally dominate in polyethylene acetabular components, whereas fatigue wear is an important wear mechanism in polyethylene TKA tibial inserts. The wear resistance of XLPE depends on the crosslink density of the material, which may decrease during in vivo mechanical loading, leading to more wear and increased oxidation. To examine this possibility, we measured crosslink density and oxidation levels in loaded and unloaded locations of retrieved tibial inserts to evaluate the short-term performance of XLPE material in TKA. Forty retrieved XLPE tibial inserts (23 remelted, 17 annealed) retrieved after a mean time of 18 ± 14 months were visibly inspected to identify loaded (burnished) and unloaded (unburnished) locations on the plateaus of each insert using a previously published damage mapping method. For each insert, four cubes (3 mm3) were cut from loaded and unloaded surface and subsurface locations (Fig. 1). Swell ratio testing was done according to ASTM F2214 to calculate crosslink density of the cubes. With a microtome, 200 μm sections were taken adjacent to the cubes and oxidation was assessed with Fourier transform infrared spectroscopy following ASTM F2102 (Fig. 2). Surface oxidation was measured in the sections adjacent the surface cubes and subsurface oxidation was measured in sections adjacent to the subsurface cubes. The effects of location (surface vs. subsurface in the loaded and unloaded regions) and thermal treatment (annealed vs. remelted) on crosslink density and oxidation were assessed with repeated measures generalized estimating equations (GEEs), with the implant treated as the repeated factor. Results are presented as means and 95% confidence intervals and the level of significance was α=0.05.Introduction
Materials and Methods
Implant position plays a major role in the mechanical stability of a total hip replacement. The standard modality for assessing hip component position postoperatively is a 2D anteroposterior radiograph, due to low radiation dose and low cost. Recently, the EOS® X-Ray Imaging Acquisition System has been developed as a new low-dose radiation system for measuring hip component position. EOS imaging can calculate 3D patient information from simultaneous frontal and lateral 2D radiographs of a standing patient without stitching or vertical distortion, and has been shown to be more reliable than conventional radiographs for measuring hip angles[1]. The purpose of this prospective study was to compare EOS imaging to computer tomography (CT) scans, which are the gold standard, to assess the reproducibility of hip angles. Twenty patients undergoing unilateral THA consented to this IRB-approved analysis of post-operative THA cup alignment. Standing EOS imaging and supine CT scans were taken of the same patients 6 weeks post-operatively. Postoperative cup alignment and femoral anteversion were measured from EOS radiographs using sterEOS® software. CT images of the pelvis and femur were segmented using MIMICS software (Materialise, Leuven, Belgium), and component position was measured using Geomagic Studio (Morrisville, NC, USA) and PTC Creo Parametric (Needham, MA). The Anterior Pelvic Plane (APP), which is defined by the two anterior superior iliac spines and the pubic symphysis, was used as an anatomic reference for acetabular inclination and anteversion. The most posterior part of the femoral condyles was used as an anatomic reference for femoral anteversion. Two blinded observers measured hip angles using sterEOS® software. Reproducibility was analysed by the Bland-Altman method, and interobserver reliability was calculated using the Cronbach's alpha (∝) coefficient of reliability.Introduction
Materials and Methods
Proper acetabular component orientation is an important part of successful total hip replacement surgery. Poorly positioned implants can lead to early complications, such as dislocation. Mal-positioned acetabular components can also generate increase wear debris due to edge loading which can cause pre-mature loosening. It is essential to be able to measure post-operative implant orientation accurately to assure that implants are positioned properly. It is difficult and potentially inaccurate to manually measure implant orientation on a post-op radiograph. This is particularly true for the immediate post-op radiograph where the patient is not as well aligned relative to the x-ray beam. However, the best time to determine if an acetabular component is mal-aligned is immediately following surgery so the patient could be taken back to the OR for immediate revision. Taking post-op CT scans is expensive and subjects the patient to increased radiation exposure, so using CT post-operatively is not done routinely. With the increased use of robotics and computer navigation at surgery there are often pre-op CT scans for total hip replacement patients. Current radiological tools do not take advantage of this pre-op CT scan for assessment of acetabular component orientation. A new software module for Mimics medical imaging software (Materialise, Leuven, Belgium) is able to overlay 3D CT data onto radiographs. We used this x-ray module to see if we could measure acetabular component orientation using the pre-op CT scan and the routine post-op x-ray that is taken immediately following total hip arthroplasty at our institution. From a prior study, we had pre-op, and post-op CT scans of a group of twenty patients who received a total hip replacement. The post-op scan was used to measure the actual acetabular component orientation, both inclination and anteversion (Figure 1). We then measured component orientation using only the pre-op CT scan and the initial post-op x-ray using the Mimics x-ray module. We created a 3D model of the pelvis from the pre-op CT using Mimics. Then, the x-ray module was used to import the post-op radiograph into the Mimics file. Using the software, the x-ray was registered to the pre-op 3D pelvis. A 3D .stl file of the acetabular component used at surgery was then imported into the Mimics file and also registered according to the post-op radiograph (Figures 2 and 3). Once the cup and pelvis were both registered to the post-op radiograph, they were exported as .stl files and the acetabular anteversion and inclination were measured using the same method we used for the post-op scan. We then compared the results of our measurements from the post-op 3D reconstruction to the 2D overlay method to determine the accuracy of this new measurement technique.Introduction
Methods
Acetabular component position is considered a major factor affecting the etiology of hip dislocation. The ‘Lewinnek safe zone’ has been the most widely accepted range for component position to avoid hip dislocation, but recent studies suggest that this safe zone is outdated. We used a large prospective institutional registry to ask: 1) is there a ‘safe zone’ for acetabular component position, as measured on an anteroposterior radiograph, within which the risk of hip dislocation is low?, and 2) do other patient and implant factors affect the risk of hip dislocation? From 2007 to 2012, 19,449 patients (22,097 hip procedures) were recorded in an IRB approved prospective total joint replacement registry. All patients who underwent primary THA were prospectively enrolled, of which 9,107 patients consented to participate in the registry. An adverse event survey (80% compliance) was used to identify patients who reported a dislocation event in the six months after hip replacement surgery. Postoperative AP radiographs of hips that dislocated were matched with AP radiographs of stable hips, and acetabular position was measured using Ein Bild Röntgen Analyse software. Dislocators in radiographic zones (± 5°, ± 10°, ± 15° boundaries) were counted for every 1° of anteversion and inclination angles.Introduction
Materials and Methods
Pelvic flexion and extension in different body positions can affect acetabular orientation after total hip arthroplasty, and this may predispose patients to dislocation. The purpose of this study was to evaluate functional acetabular component position in total hip replacement patients during standing and sitting. We hypothesize that patients with degenerative lumbar disease will have less pelvic extension from standing to sitting, compared to patients with a normal lumbar spine or single level spine disease. A prospective cohort of 20 patients with primary unilateral THR underwent spine-to-ankle standing and sitting lateral radiographs that included the lumbar spine and pelvis using EOS imaging. Patients were an average age of 58 ± 12 years and 6 patients were female. Patients had (1) normal lumbar spines or single level degeneration, (2) multilevel degenerative disc disease or (3) scoliosis. We measured acetabular anteversion (cup relative to the horizontal), sacral slope angle (superior endplate of S1 relative to the horizontal), and lumbar lordosis angles (superior endplates of L1 and S1). We calculated the absolute difference in acetabular anteversion and the absolute difference in lumbar lordosis during standing and sitting (Figure 1).Introduction
Methods
Wear-related osteolysis continues to be a concern in the long-term outcome and survivorship of total hip arthroplasty (THA) and there continues to be an emphasis on bearing materials that exhibit improved wear profiles. Oxidized zirconium metal (Oxinium®, Smith & Nephew) was developed to reduce the amount of polyethylene wear as compared to cobalt chromium femoral heads, without the risk of brittle fracture seen with older generation ceramics. There are a limited number of retrieval studies evaluating the performance of Oxinium in THA. The aims of this study were 1) to visually assess damage on the surface of a large number of retrieved Oxinium femoral heads, 2) to measure surface roughness of scratches on the surfaces of Oxinium femoral heads, and 3) to use scanning electron microscopy (SEM) to assess the integrity of the oxidized zirconium surface in damaged areas. BIOLOX From 2006 to 2013, 59 retrieved Oxinium femoral heads in THAs were collected after an average time to revision surgery of 1.64 years. The mean patient age was 61.9 years, with 32 males and 27 females. Reasons for revision surgery were recurrent dislocation (24), femoral component loosening or subsidence (13), infection (9), acetabular loosening (4), periprosthethic fracture (4), acetabular malposition (2), heterotopic ossification (2), and 1 case of leg length discrepancy. The diameters of the femoral heads were 28 mm (9), 32 mm (22), 36mm (26) and 40mm (2). Three observers visually graded surface damage on all femoral heads according to the following criteria: 1) no scratches, 2) minimal damage with one to two scratches, 3) significant damage with multiple scratches. We measured the surface roughness of retrieved Oxinium and BIOLOX Introduction
Methods
Digital templating is a critical part of preoperative planning for total hip arthroplasty (THA) that is increasingly used by orthopaedic surgeons as part of their preoperative planning process. Digital templating has been used as a method of reducing hospital costs by eliminating the need for acetate films and providing an accurate method of preoperative planning. Pre-operative templating can help anticipate and predict appropriate component sizes to help avoid postoperative leg length discrepancy, failure to restore offset, femoral fracture, and instability. A preoperative plan using digital radiographs for surgical templating for component size can improve intraoperative accuracy and precision. While templating on conventional and digital radiographs is reliable and accurate, the accuracy of templating on digital images acquired with a novel biplanar imaging system (EOS Imaging Inc, Cambridge, MA, USA) remains unknown. EOS imaging captures whole body images of a standing patient without stitching or vertical distortion, less magnification error and exposes patients to less radiation than a pelvis AP radiograph. Therefore, the purpose of this study was to compare EOS imaging and conventional anteroposterior (AP) xrays for preoperative digital templating for THA, and compare the results to the implant sizes used intraoperatively. Forty primary unilateral THA patients had preoperative supine AP xrays and standing EOS imaging. The mean age for patients was 61 ± 8 years, the mean body mass index 29 ± 6 kg/m2 and 21 patients were female. All patients underwent a THA with the same THA system (R3 Acetabular System and Synergy Cementless Stem, Smith & Nephew, TN, USA) by a single surgeon. Two blinded observers preoperatively templated using both AP xray and EOS imaging for each patient to predict acetabular size, femoral component size, and stem offset. All templating was performed by two observers with standard software (Ortho Toolbox, Sectra AB, Linköping, Sweden) [Figure 1] one week prior to surgery, and were compared using the Cronbach's alpha (∝) coefficient of reliability. The accuracy of templating was reported as the average percent agreement between the implanted size and the templated size for each component.Background
Methods
Sagittal pelvic tilt (PT) has been shown to effect the functional position of acetabular components in patients with total hip replacements (THR). This change in functional component position may have clinical implications including increased likelihood of wear or dislocation. Surgeons can use computer-assisted navigation intraoperatively to account for a patient's pelvic tilt and to adjust the position of the acetabular component. However, the accuracy of this technique has been questioned due to the concern that PT may change after THR. The purpose of this study was to measure the change in PT after THR, and to determine if preoperative clinical and radiographic parameters can predict PT changes after THR. 138 consecutive patients who underwent unilateral THR by one surgeon received standing bi-planar lumbar spine and lower extremity radiographs preoperatively and six weeks postoperatively. Patients with prior contralateral THR, conversion THR and instrumented lumbosacral fusions were excluded. PT and pelvic incidence (PI) were measured preoperatively for each patient, and PT was measured on the postoperative imaging. A negative value for PT indicated posterior pelvic tilt. Patient demographics were collected from the chart. Average age was 56.8±10.9 years, average BMI was 28.3±6.0 kg/m2, and 67 patients (48.6%) were female. Mean preoperative pelvic tilt was 0.6°±7.3° (range: −19.0° to 17.9°). We found greater than 10° of sagittal PT in 23 out of 138 (16.6%) patients in this sample. Mean post-operative pelvic tilt was 0.3°±7.4° (range: −18.4° to 15.0°). Mean change in pelvic tilt was −0.3°±3.6° (range: −9.6° to 13.5°). PT changed by less than 5° in 119 of 138 patients (86.2%). The mean difference in pre-operative and post-operative PT is not statistically significant (p = 0.395). Pre-operative PT was strongly correlated with post-operative PT (r2 = 0.88, p = 0.0001) (Figure 1). There was not a statistically significant relationship between PI and change in PT (r2 = −0.16, p = 0.06). In conclusion, based on the variability in pelvic tilt in this study population and the relatively small change in pelvic tilt following THA tilt-adjustment of the acetabular component position based on standing pre-operative imaging is likely to be of benefit in the majority of patients undergoing navigated THA. However, we have been unable to predict the relatively rare occurrence of a large change in pelvic tilt, which would confound tilt-adjusted component position.
The purpose of this study was to prospectively measure serum cobalt and chromium ion levels in patients who had MITCH Resurfacing (Stryker) and to correlate these with acetabular component orientation (anteversion and inclination). Twenty-seven patients were enrolled in the study. Serum ion levels were measured pre-operatively, six weeks, six months, twelve months and twenty-four months post-operatively. Axial CT scans of the pelvis were used to measure cup anteversion and plain radiographs used to measure cup inclination. The median serum cobalt and chromium levels at one year were 14.5 nmol/l (range, 6 nmol/l to 59 nmol/l) and 36 nmol/l (range, 17nmol/l to 63 nmol/l) respectively. The median serum cobalt and chromium levels at two years were 16.5 nmol/l (range, 6 nmol/l to 75 nmol/l) and 37.5 nmol/l (range, 13 nmol/l to 109 nmol/l) respectively. The mean cup inclination was 43° (range, 30° to 60°). The mean cup anteversion was 19° (range, 1° to 47°). There was no clear correlation with cup position and serum ion levels. There was one outlier with slightly elevated chromium (109 nmol/l) in a female with a small head size. All patients at all time points showed serum cobalt and chromium levels below the level indicating a high-risk implant (7 parts per billion or chromium >134 nmol/l and cobalt > 119 nmol/l). Our results show no clear relationship between cup position and serum metal ions in this group of patients with relatively well-positioned components
Modularity is being increasingly used throughout the world for both primary and revision total hip arthroplasty. Recently there have been concerns of increased corrosion and fretting at the modular junctions. In the SROM® modular hip system, two modular junctions are the head-neck taper junction and the stem-sleeve taper junction. The aim of this study was to investigate corrosion at these junctions with the use of different bearing materials. Between 1994 and 2012, fourty-two patients were revised with SROM® stems. Reasons for revision included aseptic loosening of the cup or stem (11), periprosthetic fracture (2), osteolysis (8), dislocation (13) and other reasons (7). One was revised for stem breakage, and this was excluded from this study. We examined 41 retrieved S-ROM® comprised of 6 metal-on-metal (MOM), 12 metal-on-polyethylene (MOP), 7 ceramic-on-polyethylene (COP) and 16 ceramic-on-ceramic (COC). The orientation for all components was marked at the time of revision surgery. Both the proximal sleeve/stem and the femoral head-neck modular junctions were examined under 10X magnification, and graded by two independent observers. The head tapers were divided into 4 regions, and graded using a previously published 3 point scoring system for fretting and corrosion damage (Goldberg et al, Kop et al), for a total corrosion damage score of 12. The SROM stems were also assessed at the sleeve/stem taper junction. Each stem was divided into 8 quadrants, and graded for corrosion and fretting using the same system as the taper. In addition to severity, we also quantified area of corrosion damage of the stem at the sleeve-stem junction from 0–3, which was multiplied by the severity of damage, to give a score out of 9 for each quadrant (maximum total score of 72 for the stem). The bearing type was unknown to the investigators, so the grading was done in a blinded fashion. Corrosion scores were divided by time to account for differences in time to revision.Introduction
Methods
Edge loading commonly occurs in all bearings in hip arthroplasty. Edge loading wear can occur in these bearings when the biomechanical loading axis reaches the edge and the femoral head loads the edge of the cup producing wear damage on both the head and cup edge. When the biomechanical loading axis passes through the polished articulating surface of the acetabular component and does not reach the edge, the center of the head and the center of the cup are concentric. The resulting wear known as concentric wear is low in metal-on-metal (MOM) bearings, and is negligible in ceramic-on-ceramic (COC) bearings. Edge loading is well defined in COC hip bearings. However, edge loading is difficult to identify in MOM bearings, since the metal bearing surfaces do not show wear patterns macroscopically. The aims of this study are to compare edge loading wear rates in COC and MOM bearings, and to relate edge loading to clinical complications. Twenty-nine failed large diameter metal-on-metal hip bearings (17 total hips, 12 resurfacings) were compared to 54 failed alumina-on-alumina bearings collected from 1998 to 2011. Most COC bearings were revised for aseptic loosening or periprosthetic bone fracture, while most MOM bearings were revised for pain, soft tissue reactions or impingement. The median time to revision was 3.2 years for the metal hip bearings and 3.5 years for alumina hip bearings. The surface topography of the femoral heads was measured using a RedLux AHP (Artificial Hip Profiler, RedLux Ltd, Southampton, UK).Introduction
Materials and Methods
In patients with conventional metal-on-Polyethylene (MoP) hip replacements, osteolysis can occur in response to wear debris. During revision hip surgery, surgeons usually remove the source of osteolysis (polyethylene) but cannot always remove all of the inflammatory granulomatous tissues in the joint. We used a human/rat xenograft model to evaluate the effects of polyethylene granuloma tissues on bone healing. Human osteoarthritic and periprosthetic tissues collected during primary and revision hip arthroplasty surgeries were transplanted into the distal femora of athymic (nude) rats. The tissues were assessed before and after implantation and the bone response to the tissues was evaluated after 1 week and 3 weeks using micro-computed tomography, histology, and immunohistochemistry. After 3 weeks, the majority (70%) of defects filled with osteoarthritic tissues healed, while only 21% of defects with polyethylene granuloma tissues healed. Polyethylene granuloma tissues in trabecular bone defects inhibited bone healing. Surgeons should remove polyethylene granuloma tissues during revision surgery when possible, since these tissues may slow bone healing around a newly implanted prosthesis. This model provides a method for delivering clinically relevant sized particles into an
Two types of ceramic materials currently used in total hip replacements are third generation hot isostatic pressed (HIPed) alumina ceramic (commercially known as BIOLOX® Ceramic bearings revised at one center from 1998 to 2010 were collected (61 bearings). Eleven Introduction
Material and Methods
Edge loading commonly occurs in all bearings in hip arthroplasty. The aim of this study compares metal bearings with edge loading to alumina bearings with edge loading and to metal bearings without edge loading. Seventeen failed large diameter metal-on-metal hip bearings (8 total hips, 9 resurfacings) were compared to 55 failed alumina-on-alumina bearings collected from 1998 to 2010. The surface topography of the femoral heads was measured using a chromatically encoded confocal measurement machine (Artificial Hip Profiler, RedLux Ltd.). The median time to revision for the metal hip bearings and the alumina hip bearings was 2.7 years. Forty-six out of 55 (84%) alumina bearings and 9 out 17 (53%) metal bearings had edge loading wear (p<0.01). The average volumetric wear rate for metal femoral heads was 7.87 mm3/yr (median 0.25 mm3/yr) and for alumina heads was 0.78 mm3/yr (median 0.18 mm3/yr) (p=0.02). The average volumetric wear rate for metal heads with edge loading was 16.51 mm3/yr (median 1.77 mm3/yr) and for metal heads without edge loading was 0.19 mm3/yr (median 0 mm3/yr) (p=0.1). There was a significant difference in gender, with a higher ratio of females in the alumina group than the metal group (p=0.02). Large diameter metal femoral heads with edge loading have a higher wear rate than smaller alumina heads with edge loading. Metal-on-metal bearings have low wear when edge loading does not occur.
Two types of ceramic materials currently used in total hip replacements are third generation hot isostatic pressed (HIPed) alumina ceramic (commercially known as BIOLOX®forte, CeramTec) and an alumina matrix composite material consisting of 75% alumina, 24% zirconia, and 1% mixed oxides (BIOLOX®delta, CeramTec). The aim of this study is to compare BIOLOX delta femoral heads to BIOLOX forte femoral heads revised within 2 years in vivo. Ceramic bearings revised at one center from 1998 to 2010 were collected (61 bearings). BIOLOX delta heads (n=11) revised between 1–33 months were compared to BIOLOX forte femoral heads with less than 24 months in vivo (n=20). The surface topography of the femoral heads was measured using a chromatically encoded confocal measurement machine (Artificial Hip Profiler, RedLux Ltd.). The median time to revision for BIOLOX delta femoral heads was 12 months, compared to 13 months for BIOLOX forte femoral heads. Sixteen out of 20 BIOLOX forte femoral heads and 6 out of 11 BIOLOX delta femoral heads had edge loading wear. The average volumetric wear rate for BIOLOX forte was 0.96 mm3/yr (median 0.13 mm3/yr), and 0.06 mm3/yr (median 0.01 mm3/yr) for BIOLOX delta (p=0.03). There was no significant difference (p>0.05) in age, gender, time to revision or femoral head diameter between the two groups. Early results suggest less volumetric wear with BIOLOX delta femoral heads in comparison to BIOLOX forte femoral heads.
