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Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_I | Pages 76 - 77
1 Jan 2011
Chuter GSJ Barwick TW Murray SA Gerrand CH
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Introduction: The workload of a bone and soft tissue tumour (BSTT) multidisciplinary team (MDT) is varied. Only a proportion of the workload attracts specific funding from the National Commissioning Group (NCG) but many patients who do not have primary malignant bone tumours are also seen and treated. We analysed the workload of our supra-regional BSTT MDT to determine the variety of conditions seen, the proportion that does not attract specific funding and the expertise required to run the service.

Methods: A prospective database was used to identify all new patients discussed at our weekly BSTT MDT meetings between 2004 and 2008 inclusively. Patients were divided by diagnosis into eight categories and further identified as to whether or not they attracted funding under NCG regulations.

Results: 1743 new patients were identified of which 83 were excluded. Of the remaining 1660, 65% were non-sarcoma and 50% were benign. 31% of the malignant workload was non-sarcoma. Only 11% of patients were eligible for NCG funding. Of those requiring surgery, the orthopaedic team managed 93% of benign and 77% of malignant cases; general, plastic, or thoracic surgical teams managed the remainder.

Discussion: NCG funds the management of all malignant primary bone tumours and the investigation and/or treatment of other selected conditions; the majority of our workload does not qualify. Despite fluctuations in the total workload, the ratio of benign to malignant cases remains relatively constant. Considerable expertise across many different specialties is essential for an effective and efficient MDT.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_I | Pages 79 - 79
1 Jan 2011
Barwick TW Chuter G Murray S Gerrand C
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Introduction: Well-differentiated liposarcomas have a tendency to recur locally but do not metastasise unless dedifferentiation occurs. In this study, a tumour superficial to the deep fascia of the trunk or limb is termed an atypical lipoma (AL) and one deep to fascia, a lipoma-like liposarcoma (LL) reflecting increased difficulty in wide local excision.

Methods: We prospectively collected data for 87 well-differentiated liposarcomas excised at our institution from 1998–2008. Data was recorded on a multidisciplinary team database and verification was undertaken using patient records. Any radiological investigation performed was determined retrospectively. Primary excisions performed elsewhere were excluded. The aim was to produce recommendations on the clinical and radiographical post-operative management of these common tumours.

Results: LL was seen in 74 patients and AL in 13 (mean age 58 years, mean follow up 5 years). The mean size of LL excisional biopsy was 148mm and 54mm for AL (p< 0.05). There were no AL recurrences. Five LL (7%) locally recurred within a mean of 5 years (range 2–10 years). All were deeply related to neurovascular structures (4 thigh-marginal/complete excisions and 1 upper arm-piecemeal excision). One recurrence was detected by MRI from 26 LL patients (35%), the other four being clinically suspected prior to re-scanning. During follow up, a chest radiograph was performed in 21 LL patients (27%) and no metastases were detected.

Discussion: Patients with a completely excised superficial AL need no routine follow up. Follow up of LL is determined by the patient, the tumour size and the location. The routine use of interval MRI to detect local recurrence of uncomplicated LL is not necessary. MRI provides ‘base-line’ post-operative information where a neurovascular bundle was closely related to the tumour or excision was incomplete. Chest radiographs are not indicated in screening for metastases in these tumours unless locally recurrent.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_I | Pages 79 - 80
1 Jan 2011
Barwick TW Chuter G Murray S Gerrand CH
Full Access

Introduction: The ‘Two Week Wait’ (2ww) process has been in force since the year 2000, with the subsequent implementation of 32-day diagnosis and 62-day treatment ‘rules’, as part of reforms to NHS cancer services. The aims of this study were to compile a definitive diagnostic profile of 2ww referrals, establish whether a histological diagnosis was required and consider the current 2ww impact on services in our centre.

Methods: Two hundred and nine patients were referred to the North of England Bone and Soft Tissue Tumour service and prospectively recorded on a computerised multidisciplinary tumour database from 2006–8. The data was reviewed and verified using pathology, radiology reports and patient records.

Results: Malignancy was diagnosed in 41(20%) patients (n=209). This comprised 21 soft tissue sarcomas (10%), 11 primary bone tumours (5%), and 9 metastatic bone tumours (4%).

63 (30%) benign bone or soft tissue neoplasia and 80 (38%) non-neoplastic conditions were diagnosed. No mass lesion was identifiable in 25 patients (12%). A diagnostic or therapeutic biopsy was undertaken in 108 (52%) patients.

Discussion: Fifteen percent of 2ww referrals to our centre have a primary bone or soft tissue malignancy. The 2ww caseload has increased significantly in recent years and non-malignant conditions (80%) must still be diagnosed within the 31 day rule. We utilise a ‘one-stop clinic’ approach, with access to ultrasound guided biopsy, and a weekly multidisciplinary meeting to facilitate timely investigation and treatment of all patients regardless of referral route.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 548 - 548
1 Aug 2008
Barwick TW Proctor P Wallace IW
Full Access

Introduction: There have been concerns regarding early loosening of the Elite Plus implant. In addition, catastrophic failure has been reported with the Zirconia ceramic head in combination with Hylamer Ultra-High-Molecular-weight-polyethylene (UHMWPE) acetabular liner.

We reviewed all patients under the care of the senior author, who had undergone Elite Plus hip arthroplasty.

Methods: All patients are under regular review in a nurse-led clinic and complications recorded.

Pre and post-operative radiographs were assessed for adequacy of cementation and evidence of loosening.

Results: 197 patients (mean age 72 years) had undergone 225 Elite Plus total hip arthroplasties since 1996. An additional 21 patients had no radiographs or case notes available at the time of review – none of these are known to have failed.

Standard UHMWPE Ogee acetabular components were used in all cases. Thirty-six percent of heads were Zirconia. Mean survivorship of all implants 5 years 2 months.

The revision rate was 2.7%. Only one revision was performed for femoral component loosening.

At latest radiographic review all patients were asymptomatic. However, 31% of femoral components were possibly loose, 5% probably loose and none definitely loose using the Harris criteria. Thirty-four percent of acetabular components were possibly loose, 8% probably loose and 1% definitely loose using Charnley/DeLee criteria.

Discussion: Our results demonstrate satisfactory performance for this hip system. We have not found significant evidence of early failure with the Zirconia and Ogee combination.

A cement restrictor, high-viscosity cement and pressurisation were used as standard. Alternative cementation techniques may partially explain early failure seen in other series.