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Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_3 | Pages 9 - 9
1 Feb 2017
Aldinger P Pawar V
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INTRODUCTION

Due to increasing interest into taper corrosion observed primarily in hip arthroplasty devices with modular tapers, efforts towards characterizing the corrosion byproducts are prevalent in the literature [1–4]. As a result of this motivation, several studies postulate cellular induced corrosion due to the presence of remarkable features in the regions near taper junction regions and articulating surfaces [3–5]. Observations made on explanted devices from a retrieval database as well as laboratory tests have led to the alternative proposal of electrocautery-electrosurgery damage as the cause of these features. These surgical instruments are commonly used for hemostasis or different degrees of tissue dissection.

METHODS

Scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS) were used to evaluate the features observed on retrieved devices. Retrieved devices consisted of OXINIUM and cobalt-chromium-molybdenum (CoCrMo) femoral implants, a Titanium-alloy hip stem, and a CoCrMo metal-on-metal femoral head. Electrocautery-electrosurgery damage was created using a SurgiStat II (Valleylab, Colorado) onto various components (CoCrMo, OXINIUM femoral heads as well as Ti-6Al-4V and CoCrMo alloy test stem constructs). Test components were evaluated using the same methods as the retrieved devices.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_34 | Pages 379 - 379
1 Dec 2013
Kretzer JP Reinders J Sonntag R Merle C Omlor G Streit M Gotterbarm T Aldinger P
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Corrosion in modular taper connections of total joint replacement has become a hot topic in the orthopaedic community and failures of modular systems have been reported. The objective of the present study was to determine in vivo titanium ion levels following cementless total hip arthroplasty (THA) using a modular neck system.

A consecutive series of 173 patients who underwent cementless modular neck THA and a ceramic on polyethylene bearing was evaluated retrospectively. According to a standardized protocol, titanium ion measurements were performed on 67 patients using high-resolution inductively coupled plasma-mass spectrometry. Ion levels were compared to a control group comprising patients with non-modular titanium implants and to individuals without implants.

Although there was a higher range, modular-neck THA (unilateral THA: 3.0 μg/L (0.8–21.0); bilateral THA: 6.0 μg/L (2.0–20.0)) did not result in significant elevated titanium ion levels compared to non-modular THA (unilateral THA: 2.7 μg/L (1.1–7.0), p = 0.821; bilateral THA: 6.2 μg/L, (2.3–8.0), p = 0.638). In the modular-neck THA group, patients with bilateral implants had significantly higher titanium ion levels than patients with an unilateral implant (p < 0.001). Compared to healthy controls (0.9 μg/L (0.1–4.5)), both modular THA (unilateral: p = 0.029; bilateral p = 0.003) and non-modular THA (unilateral: p < 0.001; bilateral: p < 0.001) showed elevated titanium ion levels.

The data suggest that the present modular stem system does not result in elevated systemic titanium ion levels in the medium term when compared to non-modular stems. However, more outliner were seen in modular-neck THA. Further longitudinal studies are needed to evaluate the use of systemic titanium ion levels as an objective diagnostic tool to identify THA failure and to monitor patients following revision surgery.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_34 | Pages 260 - 260
1 Dec 2013
Cartner J Aldinger P Fessenden M Li C
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INTRODUCTION:

The use of tapered junctions in primary hip arthroplasty has excellent results. Large heads are being used to mitigate dislocation and optimize range of motion. The prevalence of larger heads, coupled with recent findings regarding corrosion artifacts at tapered surfaces, has spurred growing interest when considering revision rates. The purpose of this study was to determine if correlations exist between severity of corrosion artifacts and head size, head offset, time in vivo, orhead material in a 15 year retrieval database.

METHODS:

Retrieved hip arthroplasty devices with CoCrMo or oxidized zirconium (OxZr) heads were investigated for corrosion artifacts in this study. Female tapered surfaces were scored independently by a panel according to the Goldberg system for assessment of corrosion. Exclusion criteria included less than 1 week in vivo, ceramic taper, and modular proximal stem sleeves. Evaluation was performed on only stem/head taper junctions. SEM analyses and a newly developed method of vertical straightness deviation (VSD) were used on a subset of devices as an additional measure to quantify corrosion within the taper contact region by measuring depth of material loss.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 412 - 412
1 Sep 2012
Merle C Streit M Inmann M Gotterbarm T Aldinger P
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Introduction

Total Hip Arthroplasty (THA) in patients after proximal femoral osteotomy remains a major challenge. Inferior survival for both cementless and cemented THA has been reported in this subgroup of patients.

Methods

We retrospectively evaluated the clinical and radiographic results of a consecutive series of 48 THAs (45 Patients) who had undergone conversion THA for failed intertrochanteric osteotomy after a mean of 12 years (2–33 years) using a cementless, grit-blasted, double-tapered femoral stem. Mean follow-up was 20 years (range, 15–25 years), mean age at surgery was 47 years (range, 13–55 years). Clinical results were evaluated using the Harris Hip Score. Kaplan-Meier survivorship analysis was performed to determine long-term outcomes for different end points.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVI | Pages 47 - 47
1 Aug 2012
Merle C Waldstein W Pegg E Streit M Gotterbarm T Aldinger P Murray D Gill H
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In pre-operative planning for total hip arthroplasty (THA), femoral offset (FO) is frequently underestimated on AP pelvis radiographs as a result of inaccurate patient positioning, imprecise magnification, and radiographic beam divergence. The aim of the present study was to evaluate the reliability and accuracy of predicting three-dimensional (3-D) FO as measured on computed tomography (CT) from measurements performed on standardised AP pelvis radiographs.

In a retrospective cohort study, pre-operative AP pelvis radiographs and corresponding CT scans of a consecutive series of 345 patients (345 hips, 146 males, 199 females, mean age 60 (range: 40-79) years, mean body-mass-index 27 (range: 29-57) kg/m2) with primary end-stage hip osteoarthritis were reviewed. Patients were positioned according to a standardised protocol and all images were calibrated. Using validated custom programmes, FO was measured on corresponding AP pelvis radiographs and CT scans. Inter- and intra-observer reliability of the measurement methods were evaluated using intra-class correlation coefficients (ICC). To predict 3-D FO from AP pelvis measurements, the entire cohort was randomly split in two groups and gender specific linear regression equations were derived from a subgroup of 250 patients (group A). The accuracy of the derived prediction equations was subsequently assessed in a second subgroup of 100 patients (group B).

In the entire cohort, mean FO was 39.2mm (95%CI: 38.5-40.0mm) on AP pelvis radiographs and 44.6mm (95%CI: 44.0-45.2mm) on CT scans. FO was underestimated by 14% on AP pelvis radiographs compared to CT (5.4mm, 95%CI: 4.8-6.0mm, p<0.001) and both parameters demonstrated a linear correlation (r=0.642, p<0.001). In group B, we observed no significant difference between gender specific predicted FO (males: 48.0mm, 95%CI: 47.1-48.8mm; females: 42.0mm, 95%CI: 41.1-42.8mm) and FO as measured on CT (males: 47.7mm, 95%CI: 46.1-49.4mm, p=0.689; females: 41.6mm, 95%CI: 40.3-43.0mm, p=0.607).

The results of the present study suggest that femoral offset can be accurately and reliably predicted from AP pelvis radiographs in patients with primary end-stage hip osteoarthritis. Our findings support the surgeon in pre-operative templating and may improve offset and limb length restoration in THA without the routine performance of CT.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVI | Pages 78 - 78
1 Aug 2012
Merle C Waldstein W Gregory J Goodyear S Aspden R Aldinger P Murray D Gill H
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In uncemented total hip arthroplasty (THA), the optimal femoral component should allow both maximum cortical contact with proximal load transfer and accurate restoration of individual joint biomechanics. This is often compromised due to a high variability in proximal femoral anatomy. The aim of this on-going study is to assess the variation in proximal femoral canal shape and its association with geometric and anthropometric parameters in primary hip OA.

In a retrospective cohort study, AP-pelvis radiographs of 98 consecutive patients (42 males, 56 females, mean age 61 (range:45-74) years, BMI 27.4 (range:20.3-44.6) kg/m2) who underwent THA for primary hip OA were reviewed. All radiographs were calibrated and femoral offset (FO) and neck-shaft-angle (NSA) were measured using a validated custom programme. Point-based active shape modelling (ASM) was performed to assess the shape of the inner cortex of the proximal femoral meta- and diaphysis. Independent shape modes were identified using principal component analysis (PCA). Hierarchical cluster analysis of the shape modes was performed to identify natural groupings of patients. Differences in geometric measures of the proximal femur (FO, NSA) and demographic parameters (age, height, weight, BMI) between the clusters were evaluated using Kruskal-Wallis one-way-ANOVA or Chi-square tests, as appropriate.

In the entire cohort, mean FO was 39.0 mm, mean NSA was 131 degrees. PCA identified 10 independent shape modes accounting for over 90% of variation in proximal femoral canal shape within the dataset. Cluster Analysis revealed 6 shape clusters for which all 10 shape modes demonstrated a significantly different distribution (p-range:0.000-0.015). We observed significant differences in age (p=0.032), FO (p<0.001) and NSA (p<0.001) between the clusters. No significant differences with regard to gender or BMI were seen.

Our preliminary analysis has identified 6 different patterns of proximal femoral canal shape which are associated with significant differences in femoral offset, neck-shaft-angle and age at time of surgery. We are currently evaluating the entire dataset of 345 patients which will allow a comprehensive classification of variation in proximal femoral shape and joint geometry. The present data may optimise preoperative planning and improve future implant design in THA.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_III | Pages 60 - 60
1 Feb 2012
Aldinger P Jung A Gatermann S Ewerbeck V Thomsen M Parsch D
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Introduction

Up to date there are only few reports in literature on the long term survival of uncemented stems. As for cemented THA, 10 year survival of at least 90% is required for any THA.

Materials and methods

We followed the first 354 consecutive implantations of an uncemented, straight femoral stem (CLS, Zimmer Inc, Warsaw, USA) in 326 patients. Mean time of follow-up evaluation was 17 years (range, 15-20 years).


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 131 - 131
1 May 2011
Seeger J Haas D Aldinger P Jaeger S Bruckner T Clarius M
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Periprosthetic tibial plateau fractures (PTPF) represent a rare but serious complication in unicompartmental knee arthroplasty (UKA). Although excellent long-term results have been reported with cemented UKA, surgeons continue to be interested in cementless fixation. The aim of the study was to compare fracture loads of cementless and cemented UKA.

Tibial components of the Oxford UKA were implanted in six paired fresh-frozen tibiae. In one set surgery was performed with cement fixation and in the other cementless components were implanted. Loads were then applied under standardised conditions to fracture the specimens.

Mean loads of 3.6 (0.7–6.9) kN led to fractures in the cemented group, whereas the tibiae fractured in the cementless group with a mean load of 1.9 (0.2–4.3) kN (p< 0.05).

The loading capacity in tibiae with cementless components is significantly less compared to cemented fixation. Our results suggest that, patients with poor bone quality who are treated with a cementless UKA are at higher risk for periprosthetic fractures.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 154 - 154
1 May 2011
Streit M Merle C Innmann M Aldinger P
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Introduction: High survival rates have been reported for the uncemented CLS Spotorno stem up to 20 years. To confirm survival at longer follow-up we report the minimum 20-year (mean, 22 years; range, 20–25 years) results using this device.

Methods: We retrospectively evaluated the clinical and radiographic results of a consecutive series of 354 total hip arthroplasties using an uncemented grit-blasted, tapered femoral stem (CLS Spotorno) in 326 patients. Mean time of follow-up evaluation was 22 years (range, 20–25 years), mean age at surgery was 57 years (range, 13–81 years). Clinical results were evaluated using the Harris Hip Score. Kaplan-Meier survivorship analysis was used to determine long term outcomes for different end points.

Results: At final follow-up, 126 patients (136 hips) had died, and 7 patients (8 hips) were lost to follow-up. Forty-one hips (12%) in 38 patients underwent femoral revision – 10 (3%) for infection, 12 (3%) for late periprosthetic fracture, and 19 (5%) for aseptic loosening of the stem. Kaplan-Meier analysis, with revision of the femoral component for any reason as the end point, revealed that the survival rate at 22 years was 86% (95%-confidence limits, 82%–90%). The survival rate with femoral revision for aseptic loosening as the end point was 93% at 22 years (95%-confidence limits, 90% – 96%).

Discussion and Conclusion: The long-term results with this type of uncemented femoral component are encouraging and compare to the best reported series in primary cemented total hip arthroplasty. Besides aseptic loosening, periprosthetic femoral fracture is an important mode of failure in the long term following uncemented THA.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 208 - 208
1 May 2011
Merle C Streit M Volz C Aldinger P
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Introduction: Continous periprosthetic bone loss after uncemented THA may lead to proximal femoral atrophy and increase the risk for aseptic loosening or peripros-thetic femoral fracture in the long-term. Little is known about the extent and the pattern of bone remodeling around stable, straight uncemented stems after 15 years.

Patients and Methods: In a prospective longitudinal study, bone mineral density (BMD) was measured in 131 patients with 146 stable, uncemented, double- tapered, grit- blasted stems (CLS Spotorno, Zimmer, Warsaw, USA) using dual- energy x-ray absorptiometry (DEXA) after a mean of 12 years (range:10–15, t1) postoperatively. Patients were followed with radiographs and Harris hip scores (HHS), and a second and third DEXA were performed at a mean follow-up of 17 years (range: 15–20, t2) and 22 years (range: 20–25, t3) using the identical protocol.

Results: We obtained a complete prospective set of data of three consecutive DEXA measurements for 37 hips (32 patients, 14 male, 18 female). In all cases regular bone ongrowth did occur and on radiographic evaluation there were no signs of loosening and no significant change in periprosthetic bone formation. There was no case of severe bone loss and no case of diaphyseal cortical hypertrophy. We analyzed the differences in overall femoral BMD (netavg) and in BMD in zones 1–7 according Gruen. There was no significant change in overall netavg BMD for both male and female patients (p> 0,05) comparing t1 and t3. We found a significant change in periprosthetic BMD in zone 7 (−6,62%, p< 0,05) in male patients and in zones 1, 6 and 7 (−8,7%/−5,1%/−14,2%, p< 0,01/0,05/0,01) in female patients.

Discussion and Conclusion: The results of our study suggest that there are no clinically relevant changes in overall periprosthetic BMD around stable, uncemented straight stems in the long- term. However, continuous bone remodeling with slow but steady proximal bone loss occurs, predominantly in female patients. Once osseous integration is observed, stress shielding remains moderate and changes in periprosthetic BMD are limited to the metaphyseal region.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 620 - 620
1 Oct 2010
Seeger J Aldinger P Bruckner T Clarius M Haas D Jäger S
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Background and Purpose: Periprosthetic tibial plateau fractures are a rare but serious complication of UKA. Since they usually appear perioperatively they can be associated with sawing defects during implantation. The aim of the study was to evaluate fracture loads and fracture patterns under particular consideration whether extended vertical saw cuts reduce the stability of the tibial plateau and increase the risk of periprosthetic tibial plateau fractures.

Material and Methods: In 6 matched paired fresh frozen tibiae (donor data: f/m = 2/4, mean age 81.2 years, mean weight 61.7kg) tibial implantation of the cemented Oxford Uni was performed in group A and with an extended vertical saw cut of 10° in group B in a randomized fashion. Before fracturing the tibiae with a maximum load of 10.0kN under standard conditions, DEXA bone density measurement and standard X-Ray were accomplished. After load induction fracture patterns and maximum fracture loads were analyzed and correlated to BMD, BMI, bodyweight (BW), age and surface area of the tibial implant.

Results: In group A a maximum load of Fmax = 3.912 (2.346–8.500) kN lead to fractures, whereas in group B all tibiae fractured with a mean load of Fmax = 2.622 (1.085–5.036) kN. The difference was statistically different with p=0.028. The induced fractures were similar to those observed in clinical practice.

Between BMI and the maximum fracture loads inducing tibial plateau fractures a significant correlation could be proven for all tibiae (r=0.643).

Discussion: The observed fracture pattern showed metaphyseal fractures similar to those observed in clinical practise. Extended vertical saw cuts weaken the bone structure and therefore raise the risk of medial tibial plateau fractures. In our study extended vertical saw cuts of 10° reduce maximum fracture loads about 30%.

We recommend special training and modified instruments for inexperienced surgeons to minimize the incidence of extended vertical saw cuts and to reduce the risk of periprosthetic fractures.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 509 - 509
1 Oct 2010
Aldinger P Aldinger G Krahmer K Omlor G Ulrich H
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Introduction: Improved biomechanics and stem fit facilitated by gender adepted dual stems and modularity has the potential to make THA easier and thereby decrease the complication rate. Increased fretting wear at the connecting interfaces may be a drawback. 10 year survival exceeding 90% is required to endorse modular necks and dual stem gender technology.

Materials and Methods: We followed the first 190 consecutive implantations of an uncemented, straight femoral stem with dual stem technology and modular necks (European Hip System (EHS)/Profemur E, Wright Medical Technology Inc., Arlington, TN, USA) and a grit blasted titanium acetabular cup with a ceramic on polyethylene bearing in 178 patients from 1992 to 1997. Mean time of follow-up evaluation was 10 (8–13) years. Titanium serum ion levels were measured to detect fretting in the metal connection.

Results: At follow-up, 21 patients (22 hips, 11.6%) had died, and 13 (14 hips, 7.4%) were lost to follow-up. One hip underwent femoral revision for a periprosthetic fracture. Overall stem survival was 99 (98–100) % at 10 years, survival with femoral revision for aseptic loosening as an end point was 100 (99–100) % at 10 years. Three acetabular components were revised, one for infection and two for aseptic loosening of the titanium shell. There was one fracture of a high offset modular neck at the laser labeling without trauma; the design was changed subsequently. The mean Harris-Hip-Score at follow-up was 88 points. 153 hips were available for radiolographic evaluation. No case of femoral or acetabular osteolysis or loosening was found. Accelerated wear was not detected on radiographs. No dislocation was found during the study period. The results showed no increased titanium serum ion levels compared to an age matched control group.

Conclusions: The complication rate with this uncemented modular gender hip system was extremely low with a high patient (and surgeon) satisfaction. The modular neck system as well as the dual stem technology proved to be reliable. The metal ion analysis revealed no elevated serum ion levels. Modular necks and dual gender stems are a reliable and durable option in primary total hip arthroplasty.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 293 - 293
1 May 2010
Aldinger P Jung A Thomsen M Ewerbeck V Parsch D
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Introduction: THA in young and active patients remains a major challenge. Uncemented femoral components have been advocated in young patients, but there are only few reports with more than 10 years follow-up.

Materials and Methods: We followed the first 153 consecutive implantations of an uncemented, straight femoral stem (CLS, Zimmer Inc, Warsaw, USA) in 141 patients. Mean time of follow-up evaluation was 17 years (range, 15–20 years), mean age at surgery was 47 years (23–55).

Results: At follow-up, 20 patients (20 hips) had died, and 7 (7 hips) were lost to follow-up. 10 patients (10 hips) underwent femoral revision–1 for infection, 4 for periprosthetic fracture, and 5 for aseptic loosening of the stem. Overall survival was 91% at 17 years (95%-confidence limits, 88%-94%), survival with femoral revision for aseptic loosening as an end point was 95% (95%-confidence limits, 93%–98%). The mean Harris-Hip-Score at follow-up evaluation was 84 points. 116 hips were available for radiolographic evaluation. Radiolucent lines (< 2mm) in Gruen zones 1 and 7 were present in 12,9% (15 hips) and 13,8% (16 hips), respectively. Radiolucencies in zones 2–6 were found in 0,9% (1 hip) – 2,6% (3 hips) on ap x-rays. Only one case of distal osteolysis was found after a previous Wagner resurfacing. No case of severe femoral osteolysis was found at follow-up.

Conclusions: The long-term results with this type of uncemented femoral component are encouraging and compare favorably with those achieved in primary cemented total hip arthroplasty in this group of young and active patients.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 271 - 271
1 May 2010
Aldinger P Jung A Ewerbeck V Parsch D
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Introduction: Despite improved cementing techniques, the long term survival of hip arthroplasty in younger patients have been disappointing. THA in this group of young and active patients remains a major challenge. Consequently, cementless components have been developed. Longer implant survival, preservation of bone stock and ‘easier’ revisions have been advocated as potential benefits of cementless stems. Up to date there are only few reports in the literature on the long term results of uncemented stems. Like in cemented THA, 10 year survival of at least 90% is required for any THA.

Materials and Methods: We followed 133 implantations of an uncemented, grit blasted straight titanium stem (CLS, Zimmer Inc, Warsaw, USA). The mean follow-up evaluation was 14 (10 – 20) years. The mean age at surgery was 37 (16 – 45) years.

Results: At follow-up, 14 patients (10,5%) had died, and 10 (7,5%) were lost to follow-up. 3 patients under-went femoral revision. One for infection an two for aseptic loosening of the stem. There was no case of clinical or radiographic loosening at the time of follow-up. Overall survival was 96% at 14 years, survival with femoral revision for aseptic loosening as an end point was 97% at 14 years. The mean Harris-Hip-Score at follow-up was 81 points (range 45–100). 96 hips were available for radiolographic evaluation. Radiolucent lines (< 2mm) in Gruen zone 1 were present in 7 hips and in Gruen zone 7 in 2 hips, respectively. Small osteolytic lesions (< 1cm) in Gruen zone 1 were present in one hip and in Gruen zone 7 in 5 hips. Larger lesions (> 1cm) were present in one case in Gruen zone 1 and 7. No osteolysis or radiolucency was found in zones 2 – 6. No case of severe femoral osteolysis was found.

Conclusions: The long-term results with this type uncemented stem in a young and active patient group are encouraging and better than those of cemented stems in this age group. We recommend the uncemented CLS stem for hip arthroplasty in young demanding patients.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 47 - 47
1 Mar 2009
Aldinger P Hauck C Clarius M
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Radiolucent lines (RL) are a common radiographic finding following Oxford Uni knee arthroplastv. These RL are commonly seen at the bone-cement interface under the tibial tray and can only be evaluated using screened radiographs. These lines occur during the first year, are well defined and remain constant for years. The clinical relevance of this phenomenon is unclear. Pulse lavage has the potential to thoroughly clean the trabecular bone by clearing the bone from bone marrow and debris and can thereby facilitate cement penetration and interdigitation into trabecular bone.

Pulse lavage can reduce the occurrence of radiolucent lines under the tibial tray by improving cement penetration and interdigitation.

Since 2001 we routinely use pulse lavage before cementing the Oxford uni implants at the Orthopä-dische Universitätsklinik Heidelberg (group A). At Nuffield Orthopeadic Center, Oxford conventional irrigation has been used before cementing (group B). At a minimum follow-up of 1 year 56 screened AP radiographs of the knee after Oxford UCA have been blinded and evaluated for radiolucency and cement penetration by an independent observer. For standardized evaluation the cement bone interface has been devided into 4 zones and a specific algorithm for evaluation of the radiographs has been developed.

Complete radiolucencies were detected in 2 cases (4%) in group A and in 13 cases (23%) in group B (p=0,001). Partial radiolucent lines were seen in 32 knees of group A (57%) and in 40 knees (71%) in group B. In zone 1 RLs were found in 31 tibias (55%) in group A, in 32 tibias (57%) in group B. In zone 2 17 (30%) group A, 29 (52%) group B. In Zone 3 4 (7%) in Gruppe A, 20 (36%) in group B. In Zone 4 6 (11%) group A, 30 (54%) group B. The differences between group A and B were significant (P=0.001) in zones 2, 3 and 4.

In group A in 14 cases (25%) RL were limited to one zone, in group B in 5 cases (9%), respectively. In 12 cases (21%) 2 zones were affected in group A (12 cases (21%) group B). RLs in 3 zones were found in 4 cases (7%) in group A and in 10 cases (18%) in group B.

Mean cement penetration (mm) was 2,3mm in group A and in 1,4mm in group B. The use of pulsed lavage led to an increase in cement penetration by a factor of 1,6 (cement penetration in group A/B zone 1: 1,4mm/0,8mm; zone 2: 2,4mm/1,5mm; zone 3: 1,4mm/0,7mm; zone 4: 4,0mm/2,4mm).

The use of pulsed lavage significantly decreases the appearance of RLs at a minimum of 1 year follow-up by increasing cement penetration into cancellous bone. Even though the clinical relevance of tibial RLs in unclear we recommend the use of pulse lavage to improve cement penetration and interdigitation with cancellous bone. Unnecessary revisions due to misinterpretation of RLs may be prevented.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 50 - 50
1 Mar 2009
Aldinger P Volz C Jung A Ewerbeck V Parsch D
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Aim: Stress-shielding is a common problem after uncemented THA that may lead to proximal femoral atrophy and consecutive aseptic loosening.

Methods: In 143 patients with 154 uncemented CLS-stems periprosthetic bone mineral density (BMD) was measured using DXA after a mean of 12 years (10–15) postoperatively (T1). Five years later the same group of patients was examined at a mean of 17 years (range: 15–20) (T2) using the identical protocol.

Results: We obtained a complete prospective set of data of two consecutive DXA measurements in 76 cases (32 men, 44 women). In all cases regular bone ongrowth did occur and there were no signs of radiographic loosening (T1 and T2). On radiographic evaluation there was no significant change in periprosthetic bone formation in all Gruen zones between T1 and T2. There was no significant change in activity and BMD. In male patients we found no significant changes in periprosthetic BMD (netavg T1–T2: −1,19%, p< 0,01), in female patients there was no significant difference either (netavg T1–T2: −1,32%,p< 0,01). We analyzed the differences in BMD in all Gruen zones (zone 1–7) comparing T1 and T2 and found no significant differences in any zone (p< 0,01).

Conclusion: This study showed that there is no significant change in periprosthetic bone mineral density in the long term using the uncemented CLS stem. There was not a single case of stress shielding in the long term. Once osseous integration has occurred the periprostethic BMD changes remain minimal in the long term.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 51 - 51
1 Mar 2009
Aldinger P Jung A Ewerbeck V Parsch D
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Introduction: THA in young and active patients remains a major challenge. Uncemented femoral components have been advocated in young patients, but there are only few reports with more than 10 years follow-up.

Materials and Methods: We followed the first 153 consecutive implantations of an uncemented, straight femoral stem (CLS, Zimmer Inc, Warsaw, USA) in 141 patients. Mean time of follow-up evaluation was 17 years (range, 15 – 20 years), mean age at surgery was 47 years (23–55).

Results: At follow-up, 20 patients (20 hips) had died, and 7 (7 hips) were lost to follow-up. 10 patients (10 hips) underwent femoral revision- 1 for infection, 4 for periprosthetic fracture, and 5 for aseptic loosening of the stem. Overall survival was 91% at 17 years (95%-confidence limits, 88%–94%), survival with femoral revision for aseptic loosening as an end point was 95% (95%-confidence limits, 93% – 98%). The mean Harris-Hip-Score at follow-up evaluation was 84 points. 116 hips were available for radiolographic evaluation. Radiolucent lines (< 2mm) in Gruen zones 1 and 7 were present in 12,9% (15 hips) and 13,8% (16 hips), respectively. Radiolucencies in zones 2 – 6 were found in 0,9% (1 hip) – 2,6% (3 hips) on ap x-rays. Only one case of distal osteolysis was found after a previous Wagner resurfacing. No case of severe femoral osteolysis was found at follow-up.

Conclusions: The long-term results with this type of uncemented femoral component are encouraging and compare favorably with those achieved in primary cemented total hip arthroplasty in this group of young and active patients.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 369 - 369
1 Jul 2008
Gallagher J Lee C Schablowski M Aldinger P Gill H Murray D
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Background: The Oxford unicompartmental knee replacement (UKR) use in the lateral compartment has been associated with a reduced flexion range and diminished femoral rollback. It is postulated that this may be due to a flat tibial tray replacing the domed anatomy of the lateral tibia, tightening the posterolateral flex-ion gap. A new design incorporating a domed tibial component and a biconcave meniscal bearing has been developed to increase; (i) the posterolateral flexion gap in deep knee flexion (ii) meniscal bearing movement and (iii) lateral femoral condyle (LFC) rollback. A cadaveric study was designed to test these three outcomes.

Methods: The sagittal plane kinematics of seven thawed fresh frozen cadaver specimens within an upright Oxford testing rig were assessed under three different conditions; (i) intact normal cadaver knee (ii) flat lateral Oxford UKR (iii) domed lateral Oxford UKR. Each condition was tested during three ranges of motion (ROM) and data recorded during a flexion or extension half cycle. Knee flexion angle (KFA) and displacement measures of the lateral collateral ligament (LCL), LFC rollback and anteroposterior meniscal bearing movement were performed throughout knee ROM using four [3 linear, 1 rotary] potentiometer devices. Potentiometer data was recorded as a voltage reading and subsequently converted to either a millimetre displacement or degree measure using a calibration formula. All data points were compared at 10 degree interpolations of KFA.

Results: The flexion half cycles demonstrated the flat Oxford lateral UKR achieved 80.7% of normal cadaveric LFC rollback. The domed Oxford lateral UKR achieved 108.8% of normal cadaveric LFC rollback. The ratio of LFC rollback in the domed to flat UKR’s was 1.35 times (134.9%). Meniscal bearing movement in flexion demonstrated a domed to flat UKR ratio of 1.3 times (129.7%). Similar values were obtained for extension half cycles in favour of the domed Oxford lateral UKR. No significant differences were identified in LCL measures.

Conclusions: The domed Oxford lateral UKR implant allows for improved bearing movement and femoral rollback when compared to the flat Oxford lateral UKR. The sagittal plane kinematics of the domed Oxford lateral UKR as represented by femoral rollback values approximate those of the normal cadaver knee.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 153 - 154
1 Mar 2008
Aldinger P Gill H Rumolo C Schneider M Murray D Breusch S
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Objectives : To determine the change in passive knee kinematics after Oxford Unicompartment Arthoplasty (UKA) (Biomet, Uk); and to compare the change in kinematics post-operatively between image guided and the normal surgical procedure.

Background: In anteromedial osteoarthritis, only the medial compartment of the knee is affected and the collateral ligaments as well as the cruciate mechanism are intact. These preconditions make the knee suitable for UKA. The operative technique of the Oxford UKA theoretically allows the surge on to replicate the natural kinematics of the knee, due to accurate ligament balancing and fully congruent meniscal bearing design of the prosthesis. Our hypothesis was that no difference in tibiofemoral kinematics is observed after UKA. In addition we also hypothesised that the results of the image guided surgery would be the same as the normal surgical procedure.

Design/Methods: To test this hypothesis, we conducted a study using 13 normal human cadaveric knees. For kinematic analysis, the Surgetics TM surgical navigation system (Praxim, France), equipped with custom written tracking software, was used. Reference markers were mounted to the proximal tibia and the distal femur. In a standardized set-up, the knee was positioned in a leg holder and preoperative kinematics of the normal knee was recorded after a para-patellar mini-incision (70–90 mm). Joint kinematics were recorded during passive knee flexion and plotted against flexion angle. Oxford UKA was performed; the standard Phase III instrumentation was used for six knees and the image guided procedure was used for seven knees. The main difference between the standard and image guided procedures was that the inter-medullary rod was not used for the image guided surgery. After the operation postoperative kinematics were recorded using the same measurement protocol. All data were processed using Matlab 6.1 analysis software (The Math Works Inc., MA, USA). Preoperative and postoperative tibiofemoral kinematics were determined and compared. The mechanical axes of the tibia and femur were determined and kinematics represented as functions of knee flexion range. Over both the flexing and extending cycles of the knee the changes in tibiofemoral rotation (& #916;ROT), tibiofemoral ab/adduction (& #916;ABD), and distances between the origins of the mechanical axes (& #916;X, & #916;Y, & #916;Z) were calculated between pre and post-operative states.

Design/Methods: To test this hypothesis, we conducted a study using 13 normal human cadaveric knees. For kinematic analysis, the Surgetics TM surgical navigation system (Praxim, France), equipped with custom written tracking software, was used. Reference markers were mounted to the proximal tibia and the distal femur. In a standardized set-up, the knee was positioned in a leg holder and preoperative kinematics of the normal knee was recorded after a para-patellar mini-incision (70–90 mm). Joint kinematics were recorded during passive knee flexion and plotted against flexion angle. Oxford UKA was performed; the standard Phase III instrumentation was used for six knees and the image guided procedure was used for seven knees. The main difference between the standard and image guided procedures was that the inter-medullary rod was not used for the image guided surgery. After the operation postoperative kinematics were recorded using the same measurement protocol. All data were processed using Matlab 6.1 analysis software (The Math Works Inc., MA, USA). Preoperative and postoperative tibiofemoral kinematics were determined and compared. The mechanical axes of the tibia and femur were determined and kinematics represented as functions of knee flexion range. Over both the flexing and extending cycles of the knee the changes in tibiofemoral rotation (& #916;ROT), tibiofemoral ab/adduction (& #916;ABD), and distances between the origins of the mechanical axes (& #916;X, & #916;Y, & #916;Z) were calculated between pre and post-operative states.

Conclusions: The image guidance system used in our study is a valuable tool for assessing pre- and postoperative knee kinematics. Oxford Unicompartmental Knee Arthroplasty with the Phase III instrumentation in the presence of the cruciate mechanism reproduces the normal kinematics of the knee very accurately. The image guided procedure, performed without the inter-medullary rod, produced similar results to the standard surgery. Image guidance has a great potential for the assessment of pre- and post-replacement kinematics of the knee joint during surgery.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_III | Pages 372 - 372
1 Oct 2006
Aldinger P Gill H Rumolo C Breusch S Murray D
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Introduction: Minimally invasive surgery (MIS) presents challenges in achieving alignment for unicompartmental knee arthroplasty (UKA). Aim: Development and assessment of an image guidance system for MIS implanted Oxford UKA.

Methods: The Surgetics platform which uses intra-operative data acquisition was chosen as the base system. Software was developed to determine height of tibial cut, image guidance of saws, alignment of components and assessment of ligament tension. The accuracy of component placement was assessed in vitro using matched pairs of knees randomised into navigated (NAV n=10) and standard manual (MAN n=10) procedures; standardised postoperative A-P and lateral radiographs were used. Pre and post-operative kinematics were assessed (NAV n=6, MAN n=7). The changes postoperatively over knee flexion and extension were calculated for tibiofemoral rotation (ΔROT) and ab/adduction (ΔABD).

Results: Accurate component placement was achieved with both methods without significant differences. Tibial cut height was more accurately in the NAV group (re-cut rate: NAV 33%, MAN 50%). NAV femoral component placement was as accurate as MAN with intramedullary rod. For the flexing cycle mean ΔROT was −0.06° (range 6.08° to −3.93°) and mean ΔABD was −0.04° (range 3.39° to −5.72°). There were no observable differences between the NAV and MAN kinematics. Overall, no observable differences were found between pre and post-operative kinematics.

Conclusions: Image guidance produces accurate placement through MIS approach and reduces the amount of tibial bone resection.