Introduction:. Backside wear has been previously reported through in-vitro and in-vivo to have a significant contribution to the total wear in rotating bearing TKRs. The present study investigated the contribution of backside wear to the total wear in the PFC Sigma rotating platform mobile bearing TKR. In addition, the wear results were compared to the computed wear rates of the PFC Sigma fixed bearing TKR, with two different bearing materials. Materials and Methods:. The commercially available PFC Sigma rotating platform mobile bearing and PFC Sigma fixed bearing total knee replacements, size 3 (DePuy, UK) were tested, with either conventional or moderately cross-linked (5 MRad) GUR1020 UHMWPE bearing materials. The computational wear model for the knee implants was based on the contact area and an independent experimentally determined non-dimensional wear coefficient [1,2,3]. The experimental wear test for the mobile bearing was force controlled using the ISO anterior-posterior force (ISO14243-1-2009). However, due to time limitation of the explicit simulation required to run the force controlled model, the simulation was run using the AP displacements taken from the experimental knee simulator which was run under the ISO AP force. The Sigma fixed bearing TKR was run under high level of anterior-posterior displacements (maximum of 10 mm). Results and Discussion:. The rotating platform bearing showed lower wear rates, compared to that of the PFC Sigma fixed bearing, for both conventional and moderately cross-linked UHMWPE bearing materials (Fig. 1). Moreover, the results showed a high contribution of backside wear to the total wear, approximately 1 mm. 3. /million cycles (∼30% of the total wear). The computational wear predictions were in good agreements with the clinical and experimental measurements [4,5]. Contrasting the effect of bearing material on wear prediction, introducing the moderately cross-linked UHMWPE as a bearing material reduced the predicted wear rates by approximately 1 mm. 3. /million cycles in rotating platform bearing, compared to more than 5 mm. 3. /million cycles in PFC fixed bearing TKR. This reduced effect of cross-linking on wear in mobile bearing was mainly attributed to the lower cross-shear ratios in these bearings, compared to fixed bearings, and the less dependency of wear in moderately cross-linked UHMWPE on the degree of cross-shear, compared to conventional UHMWPE. Decreasing the degree of cross-shear from higher values (Sigma curved insert, high kinematic) to lower ones (rotating platform bearing) changed the predicted wear rates from 8.7 to 3.3 and from 3.4 to 2.4 (mm. 3. /million cycles), for conventional and moderately cross-linked UHMWPE materials respectively (Fig. 2). Conclusion:. The modelling confirmed the previous experimental observations of very low wear with the rotating platform knee. The models also determined the level of wear from the backside of the rotating platform knee which was approximately 1 mm. 3. /million cycles. The fixed bearing knee with moderately cross linked polyethylene also showed low wear at approximately 3 mm. 3. /million cycles. These low wear rates were determined under high kinematic walking cycles conditions. Future work will consider additional conditions

The posterior-stabilized knee prosthesis is designed specifically to provide the posterior stability to a knee arthroplasty when PCL is deficient or has to be sacrificed. Posterior dislocation of such prosthesis is rare but dreaded complication. There are several causes of postoperative dislocation such as malposition of the prosthesis, preoperative valgus deformity, a defect of the extensor mechanism and overwidening of the flexion gap. Posterior-stabilized rotating-platform mobile-bearing knee implants have been widely used to further improve the postoperative range of motion by incorporation of the post and cam mechanism to improve the posterior roll back during flexion and to overcome the wear and osteolysis problems due to significant undersurface micromotion of posterior-stabilized fixed-bearing knees. But, spin-out or rotatory dislocation of the polyethylene insert can occurs as result of excessive rotation of the rotating platform accompanied by translation of the femur on the tibia after mobile-bearing total knee arthroplasty, but that is very rare. Here, authors describe an unusual case of acute 180° rotatory dislocation of the rotating platform after posterior dislocation of a posterior-stabilized mobile-bearing total knee arthroplasty. A 71-year-old male with knee osteoarthritis underwent a TKRA using posterior-stabilized mobile-bearing prosthesis. The posterior dislocation of the total knee arthroplasty occurred 5 weeks postoperatively(Fig. 1). We underwent closed reduction of posterior dislocated total knee arthroplasty resulting in a complete 180° rotatory dislocation of the rotating platform (Fig. 2). He was treated with open exploration and polyethylene exchange with a larger component. This case illustrates that dislocation of a posterior-stabilized mobile-bearing total knee arthroplasty can occur with valgus laxity, cause 90° spin-out of the polyethylene insert and closed reduction attempts may contribute to complete 180° rotatory dislocation of the rotating platform. Special attention needs to be paid to both AP and lateral view to ensure that the platform is truly reduced and not just rotated 180° as was in this case

Purpose. Prospective randomized intervention trial to determine whether patients undergoing rotating platform total knee arthroplasty have better clinical outcomes at two years when compared to patients receiving fixed bearing total knee arthroplasty as measured by the WOMAC, SF-36 and Knee Society (KSS) scores. Method. 67 consecutive patients (33 males and 34 females; average age 66 years) were randomized into either receiving a DePuy Sigma rotating platform (RP) total knee arthroplasty (29 patients) or a DePuy Sigma fixed bearing (FB) total knee arthroplasty (38 patients). Inclusion criteria included patients between the ages of 45–75 undergoing single-sided total knee arthoplasty for clinically significant osteoarthritic degeneration. Pain, disability and well-being were assessed using the WOMAC, KSS, and SF-36 preoperatively and at 6 months, 1 year and 2 years post-operatively. In addition, intraoperative measures were collected. Pre-operative radiographs were analyzed using the Kellgren and Lawrence Score, modified Scotts Scoring and mechanical axis. Post-operative radiographs were collected at 1 and 2 years and analyzed to identify evidence of prosthetic loosening, implant positioning and limb alignment. Results. The two groups were well-matched following randomization (age, BMI, side) and had no significant differences in intraoperative measures (operative time, estimated blood loss). There were no differences in the groups with respect to their preoperative radiographs. The average female patient was younger compared to their male cohorts (mean female = 63; mean male 68 p=0.005). The post-operative radiographs did not reveal any differences between RP and FB groups when comparing sagittal alignment of femoral and tibial components, patellar tilt and patellar location. With respect to clinical outcomes, both groups reported statistically significant improvements in KSS, WOMAC and SF-36 scores. There were no differences in their pre- and post-operative SF-36 mental component scores. The 1 year WOMAC function score was significantly higher (worse outcome) in the FB group (mean = 18) compared to the RP group (mean 7.8) (p < 0.01). Two year KSS scores were significantly higher (better outcome) in the FB group (mean = 95.7) compared to the RP group (mean = 85.9) (p < 0.05). Conclusion. Both rotating platform and fixed bearing total knee arthroplasty result in clinical improvement over pre-operative function, but has no effect on the mental component of the SF-36. The current study suggests that there is not a clear benefit in selecting either a rotating platform or a fixed bearing total knee system; rather both implants result in improved function. Interestingly, when comparing the results of the WOMAC and KSS, although both measure functional outcomes, when applied to the same population demonstrate differing sensitivity

INTRODUCTION. The intact, healthy human knee joint is stable under anterior-posterior (AP) loading but allows for substantial internal-external (IE) laxity. In vivo clinical studies of the intact knee consistently demonstrate femoral rollback with flexion (Hill et al., 2000, Dennis et al., 2005). A tri-condylar, posterior stabilized (PS) total knee arthroplasty (TKA) with a rotating platform bearing (TKA-A) has been designed to address these characteristics of the intact knee. The third condyle is designed to guide the femoral component throughout the entire flexion arc (AP stability and femoral rollback with flexion), while the rotating platform bearing allows for IE rotation. This study used a computer model to compare the AP and IE laxity of a new TKA-A to that of two clinically established TKAs (TKA-B: rotating PS TKA, TKA-C: fixed PS TKA) and to demonstrate improvements in AP stability, IE rotation, and femoral rollback. METHODS. A specimen-specific, robotically calibrated computer knee model (Siggelkow et al., 2012), consisting of the femur, tibia and fibula as well as the kinetic contribution of the ligaments and capsule was virtually implanted with appropriate sizes of TKA-A, TKA-B and TKA-C adhering to the respective surgical techniques. A similar extension gap was targeted for all designs. The following kinematic data resulting from applied loads and moments were analyzed: 1) Passive AP and IE laxity (AP load: ± 50 N, IE moment: ± 6 Nm) of the midpoint between the flexion facet centers (Iwaki et al., JBJS, 2000) under low compression (44 N), 2) AP position of the medial and lateral low points (LP) of the femoral component during a lunge motion (Varadarajan et al., 2008). RESULTS. The TKA-A design demonstrated decreased AP laxity compared to TKA-B and TKA-C at all evaluated flexion angles beyond full extension (Figure 1, A). Both the TKA-A and TKA-B designs demonstrated greater IE laxity than TKA-C in early and mid-flexion (Figure 1, B). Considering lunge kinematics, the TKA-A design experienced the greatest rollback (change in AP position) of both condyles throughout flexion (lateral: 13 mm, medial: 7 mm) compared to TKA-B and TKA-C (lateral: 10 mm, medial: −1 mm; lateral: 9 mm medial: 6 mm), respectively. Rollback of the lateral condyle was greater than that of the medial condyle for all designs, which is consistent with the patterns reported for the intact knee (Hill et al., 2000, Dennis et al., 2005). Furthermore, the rate of rollback was more consistent for TKA-A compared to TKA-B and TKA-C. CONCLUSION. The new tri-condylar TKA design exhibited greater AP stability at all flexion angles and greater IE laxity through mid-flexion compared to two clinically-established TKA designs. In addition, posterior femoral rollback was more continuous for this new design. We attribute these findings to the design of the third condyle and the rotating platform bearing. For any figures or tables, please contact authors directly (see Info & Metrics tab above).

Background and Purpose of Study. The Valgus knee in total knee Arthroplasty, is considered a more demanding procedure, often with ligament balance a greater challenge than seen with neutral or Varus knees. It has also frequently been suggested that prostheses with higher levels of constraint be used to avoid late-onset instability. Various lateral release techniques have also been suggested in the literature. This study is aimed at assessing the outcomes of an unconstrained, rotating platform designed prosthesis, the LCS, using our technique, in the management of severe valgus deformity. Methods. 44 knees in 42 patients with a pre-operative valgus deformity of more than 10 degrees were included in our retrospective series. We analyzed the radiographs for the degree of correction, the angle of tibial tray implantation, and femoral implantation angle, tibial slope, as well as the presence (or degree) of lift off and any complications were noted. In this group, 7 had a Valgus deformity of greater than 25 degrees, with a mean Valgus deformity of 17,36 degrees. The mean age at operation was 65. Clinical and radiological analysis was done Pre-hospital discharge and again post-operatively 6 weeks. Results. The mean coronal alignment was corrected from 17,36 degrees to 5 degrees of Valgus post operatively. 2 knees were corrected past neutral to varus alignment. There was 1 case of bearing spin out experienced early on in the series. The mean tibial implant angle was 1,7 degrees from neutral. Lift off in the early post-operative X-rays was seen in 6 patients, however at 3 month follow up the knees appeared to be well balanced. There were no infections or revisions for wear, one re-operation for bearing dislocation, and no cases of loosening in our series. There were no cases of delayed instability. Patient satisfaction was 86 %. Conclusions. The rotating platform, mobile bearing prosthesis, using our technique, provided a reproducible correction of deformity in Valgus knees, a well-balanced knee, a low complication rate, and an excellent degree of patient satisfaction. NO DISCLOSURES

Introduction. Electromyography (EMG) is the best known method in obtaining in vivo muscle activation signals during dynamic activities, and this study focuses on comparing the EMG signals of the quadriceps muscles for different TKA designs and normal knees during maximum weight bearing flexion. It is hypothesized that the activation levels will be higher for the TKA groups than the normal group. Methods. Twenty-five subjects were involved in the study with 11 having a normal knee, five a rotating platform (RP) posterior stabilized (PS) TKA, and nine subjects with a PFC TC3 revision TKA. EMG signals were obtained from the rectus femoris, vastus medialis, and vastus lateralis as the patients performed a deep knee bend from full extension to maximum flexion. The data was synchronized with the activity so that the EMG data could be set in flexion-space and compared across the groups. EMG signals were pre-processed by converting the raw signals into neural excitations and normalizing this data with the maximum voluntary contraction (MVC) performed by the subject. The signals were then processed to find the muscle activations which, normalized by MVC, range from 0 to 1. Results. The average muscle activations for each of the three groups are shown in Figures 1, 2, and 3 for the rectus femoris, vastus medialis, and vastus lateralis respectively. The vastus medialis had the highest activation of the muscles during the weight bearing activity from 0 to 90 degrees flexion. On average, the trend seen is that the normal group had lower muscle activation levels to perform the weight bearing activity as opposed to the TKA groups which supports our hypothesis. The PS RP TKA had lower peak values than the PFC TC3 TKA. Discussion. EMG analysis provides insight into muscle activation during dynamic activities. When designing TKA devices for implantation, the patient themselves must be taken into account. In a subject with deficient ligaments, a more constrained device can make day-to-day activities easier, but at the expense of extra effort in achieving higher flexion activities. The high constraints within the PFC TC3 may cause the patient to have to put more effort into the activity. The rotating platform TKA had closer to normal muscle activation levels for the maximum weight bearing knee flexion activity

Some mobile bearing knee replacement designs have shown truly excellent long-term clinical results. The higher laxity of a mobile bearing helps reduce the shear forces and torques transmitted to the prosthesis-bone interface, and this could only help reduce the risk of loosening. Some argue that self-alignment of a mobile bearing rotationally can produce more central patellar tracking. However, the most commonly assumed benefit of mobile bearings is the reduction in contact stress, which is typically expected to reduce fatigue and wear. In a rotating platform TKR for example, wear is also expected to be less because the rolling/sliding motion is separated from the transverse rotational motion onto two separate articulating surfaces, thus less cross-paths and less wear. Such expectations may have dominated the thinking and perhaps even clouded the expectations of TKR wear test engineers. Such wear reduction however has not really been categorically proven clinically. This paper combines in-vitro wear results from two separate laboratories, one in Nebraska USA and one in Germany. These two (industrially unattached labs) possess between them a very large set of in-vitro wear testing results across the widest variety of fixed and mobile bearing TKR designs. Fortunately, the wear testing methodology using the force-control regime used in the two labs was largely similar, and was highly consistent within each lab. The fixed and the mobile bearings were subjected to the exact same force fields, allowing their Anterior-Posterior translation and internal-external rotation kinematics to vary based on the individual TKR design. Tens of implant designs have been tested, both fixed and mobile, in total (bycondylar) form and unicompartmental, of various sizes. Some mobile bearings had rotating platforms and some were rotating-translating. Some of the tests specifically compared mobile to fixed bearing tibial components using identical femoral components. Between both labs, and across all tests, no statistically significant difference resulted in wear between fixed and mobile bearings. Yet, such differences did clearly feature with known superior bearing materials (for wear) and other favored design features. Also, generally, the force-control test methodology has proven highly discriminatory in its simulation and measurement of wear as a potential clinical failure mode. The take home message to test engineers is to expect the wear of both mobile and fixed bearings to depend more on the detailed design and materials of the TKR than on the mobility of the bearing. The results of this study re-confirm the need for wear testing to be performed prior to any clinical use on all implant designs, despite seemingly similar predicates or success of some mobile bearings

INTRODUCTION. Implant wear testing is traditionally undertaken using standardized inputs set out by ISO or ASTM. These inputs are based on a single individual performing a single activity with a specific implant. Standardization helps ensure that implants are tested to a known set of parameters from which comparisons may be drawn but it has limitations as patients perform varied activities, with different implant sizes and designs that produce different kinematics/kinetics. In this study, wear performance has been evaluated using gait implant specific loading/kinematics and comparing to a combination deep knee bend (DKB), step down (SD) and gait implant specific loading on cruciate retaining (CR) rotating platform (RP) total knee replacements (TKR). This combination activity profile better replicates patient activities of daily living (ADL). METHODS. Two sets of three ATTUNE. ®. size 5 right leg CR RP TKRs (DePuy Synthes, Warsaw, IN) were used in a study to evaluate ADL implant wear. Implant specific loading profiles were produced via a validated finite element lower limb model [1] that uses activity data such as gait (K1L_110108_1_86p), SD (K1L_240309_2_144p), and DKB (K9P_2239_0_9_I1) from the Orthoload database [2] to produce external boundary conditions. Each set of components were tested using a VIVO joint simulator (AMTI, Watertown, MA, Figure 1) for a total of 4.5 million cycles (Mcyc). All cycles were conducted at 0.8Hz in force-control with flexion driven in displacement control. Bovine calf serum lubricant was prepared to a total protein concentration of 18g/L and maintained at 37°±2°C. Wear of the tibial inserts was quantified via gravimetric methods per ISO14243–2:2009(E). Polyethylene tibial insert weights were taken prior to testing and every 0.5Mcyc there after which corresponded to serum exchange intervals. The multi-activity test intervals were split into10 loops of 1,250 DKB, 3,000 SD, and 45,750 gait cycles in series. Based on activity data presented by Wimmer et al. the number of cycles per activity and activities used is sufficient for a person that is considered active [3]. A loaded soak control was used to compensate for fluid absorption in wear rate calculations. Wear rates were calculated using linear regression. RESULTS SECTION. The wear rate for the gait-only activity test was calculated to be 0.20±0.04mg/Mcyc conversely the wear rate for the multi-activity test was 2.65±0.67mg/Mcyc (Figure 2). Wear scars can be found in Figure 3. Using a two-sided t-test of unequal variance, it was found that there was a significant difference between the two wear rates (p=0.004). DISCUSSION. Adding activities to the wear simulation test significantly increased the average wear rate of the test samples, confirming that changes in cross shear from different activities will tend to increase the wear of an implant. The results of this study prove that single activity wear testing may not be the most clinically severe wear testing that can be used for pre-clinical wear assessment. For any figures or tables, please contact the authors directly

Introduction. In an effort to provide a TKA bearing material that balances resistance to wear, mechanical failure and oxidation, manufacturers introduced antioxidant polyethylene. In many designs, this is accomplished through pre-blending the polymer with the antioxidant before consolidation and radiation crosslinking. This study reports the wear performance (in terms of thickness change) of a hindered phenol (PBHP) UHMWPE from analysis of an early series of knee retrievals and explores these questions: 1) What is early-time performance of this new bearing material? 2) Is there a difference in performance between fixed and mobile bearings in this design? 3) How does quantitative surface analysis help understand performance at the insert-tray modular interface?. Methods. A series of 100 consecutive Attune™ knee inserts (DePuy Synthes, Warsaw, IN) received at revision by an IRB approved retrieval laboratory between September 2014 and March 2019 were investigated. In vivo duration was 0–52 months. Both the fixed bearing design (n=74) and the rotating platform mobile bearing design (n=26) were included. Dimensional change was determined by measurement of each insert and compared to the as-manufactured dimensions, provided by the manufacturer. The insert-tray interfaces under the loaded bearing zones were analyzed with light interferometry using an optical surface profiler (NewView™ 7300, Zygo, Middlefield, CT). Statistical analyses to explore relationships between measured variables were conducted using SPSS. Results. Mean total through-thickness change of the inserts was 0.052 mm. Mean rate of thickness change for all inserts having in vivo duration > 12 months was 0.038 mm/year (fixed bearing 0.042, mobile bearing 0.029 mm/year). The rate of thickness change for all inserts showed a decreasing trend with duration that was not statistically significant, (rho -.244, p=.094); however, the mobile bearing cohort alone showed a significant decrease in thickness change rate with duration (rho= −.659; p=.014). Surface roughness (Sa) of the distal surface of the UHMWPE inserts under the bearing areas averaged 1.24 µm (range 0.12 – 8.53) and peak-to-valley height (PV) averaged 27.1 µm (range 4 – 95). Sa and PV both showed a decreasing trend with duration in vivo in the mobile bearing inserts, but that trend did not reach statistical significance (p= 0.05 criterion). Neither Sa nor PV showed correlation with measured thickness change. Discussion. This study indicates that the rate of thickness change of a relatively new antioxidant cross-linked bearing material is very similar to other reported wear rates of crosslinked knee inserts. Lower wear rate of mobile bearing inserts compared to fixed bearings also is consistent with earlier published studies. Direct comparison between quantitative thickness change and objective, quantitative surface metrology on the same series brings new information to the arena of measuring and reporting “wear” of UHMWPE and underscores the importance of the distinction between visual damage and actual thinning of the bearing. The systematic surface analysis of the modular interfaces showing that surface roughness (Sa) and total damage feature topography (PV) trend downward with in vivo duration of mobile bearings supports the hypothesis that relative motion at that interface may ‘polish out’ the surface topography over time. For any figures or tables, please contact authors directly

Instability currently represents the most frequent cause for revision total knee replacement. Instability can be primary from the standpoint of inadequately performed collateral and/or posterior cruciate ligament balancing during primary total knee replacement or it may be secondary to malalignment/loosening which can develop later progressive instability. Revision surgery must take into consideration any component malalignment that may have primarily contributed to instability. Care should be given to assessing collateral ligament integrity. This can be done during physical examination by radiological stress testing to see if the mediolateral stress of the knee comes to a good endpoint. If there is no sense of a palpable endpoint, then the surgeon must assume structural incompetency of the medial or lateral collateral ligament or both. In posterior cruciate retaining knees, anteroposterior instability must be assessed. For instability, most revisions will require a posterior cruciate substituting design or a constrained condylar design that is unlinked. However, if the patient displays considerable global instability, a linked, rotating platform constrained total knee replacement design will be required. Recent data has shown that the rotating hinges work quite well in restoring stability to the knee with maintenance of the clinical results over a considerable length of time. Intramedullary stems should be utilised in most cases when bone integrity is suspect and insufficient. Infection should be ruled out by aspiration and off of antibiotics prior to any revision operation, especially if loosening of the components represents the cause of instability. The surgeon should attempt to restore collateral ligament balance whenever possible as this yields the best clinical result

There exists a variety of options for a medial compartment knee with osteoarthritis, specifically a unicompartmental knee, high tibial osteotomy, and total knee arthroplasty. This surgeon prefers a rotating platform posterior stabilised total knee to the unicompartmental knee. Unicompartmental knee arthroplasty (UKA) in younger patients is being performed with increasing frequency. While UKA is a powerful marketing tool because of its minimally invasive nature and quality of knee function that is superior to the total knee arthroplasty (TKA), it has tremendous drawbacks. These include: the selection criteria is very specific and the number of patients that fit in that category is small, there is a steep learning curve for the surgeon to perfect the technique, higher failure due to wear and loss of fixation, and unexplained pain. Based on level 1 and 2 evidence available it is not justified to do more UKAs at present when the results of a TKA are so successful

Introduction: Although volumetric wear reduction has been demonstrated in knee simulator studies, there is no long-term in-vivo evidence supporting wear reduction and durability with uni-directional rotating platform PS design. This design was introduced to reduced spin-out and provide greater range of motion. This is the first long-term report of this implant, a prospective study investigating clinical and radiographic survivorship with 10 years follow-up. Material and Methods: Between January 2000 to March 2001, 118 consecutive patients (141 knees) received cemented RP TKRs. All patients were followed prospectively using clinical and radiographic criteria as defined by the Knee Society. At minimum nine years follow-up 20 patients were deceased, 11 were lost to follow-up and two refused to participate in the study, leaving 85 patients (100 knees) for final analysis. Results: Good to excellent results were achieved in 95% of patients. There were no cases of malalignment, spinout, aseptic loosening or osteolysis. The mean ROM improved from 111.2 ± 15.2 degrees to 119 ± 3.8 degrees. The mean WOMAC score was 30 ± 14, KSS scores improved from an average of 48 to 96. Sporting activities such as golf, tennis and walking was 29%, 12% and 32%, respectively. Anterior knee pain was present in 15% of cases. The incidence of asymptomatic crepitation and painful crepitation requiring scar excision was 10% and 4% respectively. During this period we had one case of infection and one revision for fracture. Kaplan-Meier survivorship at 10 years for mechanical failure and failure for all failures was 100% and 95.7%, respectively. Discussion and Conclusion: Ten-year follow-up of RP-PS design demonstrates excellent clinical and radiographic results with no failures for mechanical reasons. There were no spin-out and average ROM was 119 ± 3.8 degrees

Why are total knees being revised? Aseptic loosening, poly wear, and instability account for up to 59% of revision TKA procedures. Younger and more active patients are placing greater demands on total knee arthroplasty (TKA) implants and international registries have documented a much higher rate of TKA failure in this population. Implant designs utilised in the active patient population should focus on optimisation of long term wear properties and minimising interface stress. Instability after TKA, often related to technical concerns at the time of the index procedure, accounts for by far the greatest subset of failures, excluding infection, in the early revision TKA patients (<5 years). The inability to achieve a rectangular flexion gap with certain TKA techniques for certain deformities has been documented. The adverse clinical consequence of flexion gap asymmetry has also been published in peer reviewed manuscripts. Techniques should be considered that optimise flexion space balance and enhance mid-flexion stability in active, physically demanding patients. This surgical demonstration will highlight gap balancing techniques and a new rotating platform TKA system as an option for the active patient population

Sagittal stability of the knee is believed to be of significant importance following total knee arthroplasty. We examine four different knee designs at a minimum of twenty-four months postoperatively. Sagittal stability was measured at four degrees of flexion: 0°; 30°; 60°; and 90°, to examine the effect of design on mid-flexion stability. The knee designs included were: the rotating platform LCS design (DePuy); the cruciate sparing Triathlon system (Stryker); SAIPH system (Matortho, UK); and the medial rotating knee design, MRK (Matortho, UK). Following ethical approval, 64 cases were enrolled into the study, 22 male and 42 female. Inclusion criteria included: a minimum of 18 months from surgery; ability to flex beyond 90 degrees; and have no postoperative complications. 18 LCS, 18 MRK, 14 SAIPH and 14 Triathlon knee designs were analysed. Sagittal stability was measured using the KT1000 device. Active range of movement was measured using a hand held goniometer and recorded as was Oxford knee score, WOMAC knee score, SF12 and Kujala patellofemoral knee score. Mean follow-up was 33.7 months postoperative, with a mean age of 72 years. Mean weight was 82.7kgs and height 164cms. There was no significant difference in preoperative demographics between the groups. Mean active post-operative range of motion of the knee was from 2–113° with no significant difference between groups. Sagittal stability was similar in all four groups in full extension; however the MRK and SAIPH designs showed improved stability in the mid-range of flexion (30–90°). Patient satisfaction also showed a similar trend with MRK achieving better patient reported functional outcomes and satisfaction than that of the SAIPH, LCS and Triathlon systems. All four knee designs demonstrated good post-operative range of movement with comparative improvement of patient scores to other reported studies. The MRK and SAIPH knee design showed an improved mid-flexion sagittal stability with better patient reported satisfaction and functional scores

Whether to preserve the posterior cruciate ligament in total knee arthroplasty remains a topic of debate. Long term studies out to 20 or more years have shown both posterior-stabilised (PS) as well as cruciate-retaining (CR) total knees to perform well. Studies supporting both sides are abundant, and there are even studies supporting one being superior to the other, and vice versa. In closer examination of this issue through a recent meta-analysis, the following conclusions can be drawn: . Flexion: mean difference of 2.24, favoring PS designs (p = 0.009). Range of Motion: mean difference of 3.33, favoring PS designs (p = 0.0009). Complications: no statistical difference between PS vs CR. Proprioception. Swanik et al. – PS knee patients were more accurate at reproducing joint position. My bias: PS knees can be utilised in all patients with all deformities. Patellar crepitance with PS designs can be minimised with design alternations and techniques for patella preparation. Any issues with post impingement can be minimised using PS rotating platform designs. The debate of PS vs CR total knees remains unresolved. There is not a 100% clear advantage. Surgeons should make their choice based on their own clinical outcomes, objectively monitored over the long term. For me personally, the choice is PS

Instability currently represents the most frequent cause for revision total knee replacement. Instability can be primary from the standpoint of inadequately performed collateral and/or posterior cruciate ligament balancing during primary total knee replacement or it may be secondary to malalignment secondary to loosening and settling of the implants which can develop later progressive instability. Revision surgery must take into consideration any component malalignment that may have primarily contributed to instability. Also, collateral ligament integrity may change following total knee replacement slightly after complete correction of a severe deformity that presents rarely as instability after several months. Care should be given to assessing collateral ligament integrity. This can be done during physical examination by manual or radiological stress testing to see if the mediolateral stress of the knee comes to a good endpoint. If there is no sense of a palpable endpoint, then the surgeon must assume structural incompetency of the medial or lateral collateral ligament or both. In posterior cruciate ligament retaining knees, anteroposterior instability must be assessed. For instability, most revisions will require a posterior cruciate substituting design or a constrained unlinked condylar design. Occasionally, a posterior cruciate ligament preserving design can be used in situations where the bone-stock is well preserved and the posterior cruciate ligament shows excellent structural integrity. However, if the patient displays considerable global instability, a linked, rotating platform constrained total knee replacement design will be required. Recent data has shown that the rotating hinges work quite well in restoring stability to the knee with maintenance of the clinical results over a considerable length of time. Revision can range from simple polyethylene insert exchange to a thicker dimension, isolated component revision or complete revision of both femoral and tibial devices. During revision surgery, laminar spreaders may be utilised to assess the flexion and extension spaces after the tibial platform is restored. If a symmetric flexion and extension space is achieved, then the collateral ligaments are intact. Depending on the remaining existing bone stock, a posterior stabilised or constrained condylar unlinked prosthesis may be used for implantation. In cases with considerable asymmetry or a large flexion/extension mismatch, a rotating hinge design should be utilised. Intramedullary stems should be utilised in most cases when bone integrity is suspect and insufficient. Currently, stems should be placed cementless to permit easier future revision. Cementing the stems is only recommended if there is lack of intramedullary isthmic support or there is a hip prosthetic stem that prohibits a stem from engaging the isthmic cortex. However, it should be realised that later revision of the fully cemented revision implant may be quite difficult. Infection should be ruled out by aspiration off of antibiotics prior to any revision operation, especially if loosening of the components represents the cause of instability early. The surgeon should attempt to restore collateral ligament balance whenever possible as this yields the best clinical result

The natural knee allows multi-planar freedoms of rotation and translation, while retaining stability in the antero-posterior direction. It allows flexion with roll back, and medial, lateral and central rotation movements. The natural femoral condyles of the knee are spiral, therefore inducing a side to side translatory movement during flexion and extension. Incorporating all these features is vital in successful knee replacement design. The different knee designs currently in use demonstrate different deficiencies in knee function. A study of 150 Posterior Cruciate (PCL) Retaining Total Knee Replacements [1] has shown that in 72% of knees direct impingement of the tibial insert posteriorly against the back of the femur was responsible for blocking further flexion. The mean pre-operative range of flexion was 105° and post-operative was 105.9°. For every 2mm decrease in posterior condylar offset, the maximum flexion was reduced by 12.2°. The major disadvantage of the Posterior Stabilised (PS) Total Knee Replacement is gross anterior to posterior mid-flexion instability [2]. The Medial Rotation Total Knee Replacement is good in mid-flexion but not in high flexion where the femur slides forward on the tibia leading to impingement. The Birmingham Knee Replacement (BKR) is a rotating platform knee design which is stable throughout the range of flexion. In high flexion, the BKR brings the femur to the back of the tibia. The BKR also has spiral femoral condyles, matching the natural kinematics of the knee. The combined static and dynamic effect is 10mm lateral translation of the femur in flexion and vice versa in extension. Results for seventy nine BKRs (in seventy two patients) show the best Oxford Knee Score of 12 at follow up – excluding ten patients whose inferior scores were due to other pathologies. Knee flexion results show a 21° post-operative improvement in range of flexion. On objective independent testing, maximum walking speed is slower for patients with a standard knee replacement (6.5km/h) and the loading through the replaced side does not match the normal side. Comparatively, patients with a BKR have a faster maximum walking speed of 11km/h and the loading closely matches that of the normal knee. Studies based on the National Joint Register PROMs data [2] show that nearly thirty percent of Total Knee Replacement patients are not much better since their operation. A lot of improvement is needed in the design of knee replacements in order to achieve better function for knee replacement patients

To restore a physiologic kinematic is one of the goals of total knee replacement (TKR). This study compared the intra-operative registration of the knee kinematics during standard, navigated TKR performed either with a well validated floating platform design with posterior cruciate (PCL) preservation, or with a newly designed TKR with a rotating platform and PCL substitution. It was hypothesised that this new design will significantly alter the kinematic recorded after TKR implantation in comparison to the conventional design. A standard navigation software has been modified to allow the intra-operative registration of the knee kinematic during a flexion-extension movement before and after implantation. Kinematic registration was performed twice: 1) before any bone resection or ligamentous balancing; 2) after fixation of the final implants. Post-operative kinematic was classified as following: 1) Occurrence of a normal femoral roll-back during knee flexion, no roll-back or paradoxical femoral roll-forward. 2) Occurrence of a normal tibial internal rotation during knee flexion, no tibial rotation or paradoxical tibial external rotation. 20 patients were operated on with either the PCL preserving or sacrificing designs. The kinematic behaviour was compared on a patient specific basis before and after the TKR. About femoral roll-back, 54% had a normal femoral roll-back during knee flexion after total knee replacement, 13% had no significant roll-back and 33% had a paradoxical femoral roll-forward. About tibia rotation, 65% had a normal tibia internal rotation during knee flexion, 16% had no significant tibia rotation and 19 had a paradoxical tibia external rotation. There was no difference of repartition between the two designs. The new software allows actually validating new designs of a TKR in terms of intra-operative kinematic behaviour

Introduction. LCS total knee arthroplasty was used in many nations worldwide. This implant's features are not only mobile bearing but also has very unique concepts of mechanism. Meniscal bearing (MB) is a one of the types of implant. 2 separate bearings move on the tibia plate. This implant has been known to need revision in cases of over ten years. F.F. Buechel. 1). reported a 5% revision rate at an average of 10.1 years. On the other hand, another type of implant, which is a rotating platform bearing LCS, had only 1.2% at an average of 9.9 years. Patients and Methods. We used the meniscal bearing type LCS (MB-LCS) 289 knees from May 1995 to Dec. 2005. All cases were supervised by chief surgeon Makoto Kobori. He reported on the long term follow up of LCS until 2006. There were 18 cases revision of the MB-LCS (revision rate 6%) and in all cases only the meniscal bearings were replaced. 2). We followed further until April 2014. Results. After 2006, we have had many revision cases of MB-LCS. We followed on those 289 knees until April 2014. The follow up rate was 76.2% (lost follow up 69 knees / 289 knees). 32 knee revision out of 289 knees of MB. 29 knees had only MB replaced and 3 knees needed to have all components changed. There was one case of infection after replacing MB. The MB-LCS revision rate was 11% at an average of 11 years, which is clearly an increase over other reports. Discussion. Production of MB-LCS was stopped in recently. Because there was a high revision rate, difficult for surgery due to the unique mechanism and less market share. Buechel said the polyethylene wear problems due to sterilization of the bearing by a gamma irradiation in air process which resulted in high oxidation when left on an inventory shelf. 1). Fortunately, MB-LCS revision was easy to replace only the MBs in many knees. However the implant maker stopped making MB, creating an unacceptable problem. t We hope for the continued production of MB for revision surgery

With the introduction of new technology in orthopaedics, surgeons must balance anticipated benefits in patient outcomes with challenges or complications associated with surgical learning curve for the technology. The purpose of this study was to determine whether surgeon learning curve with a new multi-radius primary TKA system and instruments designed to improve surgical team ease would impact clinical outcomes, surgical time, and complications. From November 2012 to July 2015, 2369 primary TKAs were prospectively enrolled in two multicentre studies across 50 sites in 14 countries with a new knee system (NEW-TKA) evenly balanced across four configurations: cruciate retaining or posterior stabilised with either fixed bearing or rotating platform (CRFB, CRRP, PSFB, PSRP). 2128 knees had a<1 year visit and 1189 had a minimum 1 year visit. These knees were compared to a reference dataset of 843 primary TKAs from three manufacturers in the same four configurations with currently available products (CA-TKA). Demographics for NEW-TKA and CA-TKA were similar and typical for primary TKA. Operative times, clinical outcomes and a series of five patient reported outcomes were compared for NEW-TKA vs. CA-TKA. The first 10 New-TKA subjects for each surgeon were defined as learning curve cases (N=520) and were compared to all later subjects (N=1849). Patient reported outcome measure and clinical outcome analyses were covariate adjusted for patient demographics, pre-op assessment and days post-op. Mean (SD) surgical time for NEW-TKA learning curve cases was 79.1 (24.3) minutes, which reduced thereafter to 73.6 (24.3) (p=0.002). Beyond 10 cases, there was a continued reduction in NEW-TKA surgical time (R-Squared = 0.031). After 10 cases, surgical time was on par with the mean (SD) 71.9 (21.6) for CA-TKA (p=0.078). PROM outcomes of the first 10 learning curve cases for NEW-TKA were not statistically different from later cases at less than 1 year or later when adjusted for relevant covariates including configuration, patient demographics, pre-op functional status, and time post-op (p-values > 0.01). PROM outcomes for NEW-TKA vs. CA-TKA under the same covariate adjustments showed a trend favoring KOOS ADL, Symptoms, and Sport and Recreation subscores at minimum 1 year (p-values < 0.01). The incidence of intraoperative operative site complications was 1.3% for the NEW-TKA learning curve cases which was similar to the 0.6% rate for historical CA-TKA (p=0.231) and the intraoperative complication rate for the NEW-TKA later cases was consistent with learning curve cases (p=0.158). The introduction of new implants into the market place needs to have adequate data to support that they are safe and effective. Except for a minor increase in surgical time during the first 10 patients, this study found that surgeon learning curve with this new primary TKA system does not adversely affect patient short term outcomes and complication rates