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Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_10 | Pages 72 - 72
1 Oct 2022
Fes AF Pérez-Prieto D Alier A Verdié LP Diaz SM Pol API Redó MLS Gómez-Junyent J Gomez PH
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Aim. The gold standard treatment for late acute hematogenous (LAH) periprosthetic joint infection (PJI) is surgical debridement, antibiotics and implant retention (DAIR). However, this strategy is still controversial in the case of total knee arthroplasty (TKA) as some studies report a higher failure rate. The aim of the present study is to report the functional outcomes and cure rate of LAH PJI following TKA treated by means of DAIR at a long-term follow-up. Method. A consecutive prospective cohort consisting of 2,498 TKA procedures was followed for a minimum of 10 years (implanted between 2005 and 2009). The diagnosis of PJI and classification into LAH was done in accordance with the Zimmerli criteria (NEJM 2004). The primary outcome was the failure rate, defined as death before the end of antibiotic treatment, a further surgical intervention for treatment of infection was needed and life-long antibiotic treatment or chronic infection. The Knee Society Score (KSS) was used to evaluate clinical outcomes. Surgical management, antibiotic treatment, the source of infection (primary focus) and the microorganisms isolated were also assessed. Results. Among the 2,498 TKA procedures, 10 patients were diagnosed with acute hematogenous PJI during the study period (0.4%). All those 10 patients were operated by means of DAIR, which of course included the polyethylene exchange. They were performed by a knee surgeon and/or PJI surgeon. The failure rate was 0% at the 8.5 years (SD, 2.4) follow-up mark. The elapsed time between primary total knee replacement surgery and the DAIR intervention was 4.7 years (SD, 3.6). DAIR was performed at 2.75 days (SD 1.8) of the onset of symptoms. The most common infecting organism was S. aureus (30%) and E. coli (30%). There were 2 infections caused by coagulase-negative staphylococci and 2 culture-negative PJI. All culture-positive PJI microorganisms were susceptible to anti-biofilm antibiotics. The source of infection was identified in only 3 cases. The mean duration of antibiotic treatment was 11.4 weeks (SD 1.9). The postoperative clinical outcomes were excellent, with a mean KSS of 84.1 points (SD, 14.6). Conclusions. Although the literature suggests that TKA DAIR for acute hematogenous periprosthetic joint infection is associated with high rates of failure, the results presented here suggest a high cure rate with good functional outcomes. Some explanations for this disparity in results may be the correct diagnosis of LHA, not misdiagnosing acute chronic PJI, and a thorough debridement by surgeons specialized in PJI


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_8 | Pages 71 - 71
1 May 2019
Chow J
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The goals of a total knee arthroplasty include approximation of the function of a normal knee and achievement of balance post-surgery. Accurate bone preparation and the preservation of natural ligaments along with a functional knee design, holds the potential to provide a method of restoring close to normal function. Although conventional knee arthroplasty is considered a successful intervention for end-stage osteoarthritis, some patients still experience reduced functionality and in some cases, require revision procedures. With conventional manual techniques, accurate alignment of the tibial component has been difficult to achieve. Even in the hands of skilled knee surgeons, outliers beyond 2 degrees of the desired alignment may occur in as many as 40%-60% of cases using conventional methods, and the range of component alignment varies considerably. Similarly, for total knee replacement outliers beyond 2 degrees of the desired alignment may occur in as many as 15% of cases in the coronal plane, going up to 40% of unsatisfactory alignment in the sagittal plane. Robotics-assisted arthroplasty has gained increasing popularity as orthopaedic surgeons aim to increase accuracy and precision of implant positioning. With advances in computer generated data, with image free data, surgeons have the ability to better predict and influence surgical outcomes. Based on planned implant position and soft tissue considerations, robotics-assisted systems can provide surgeons with virtual tools to make informed decisions for knee replacement, specific to the needs of the patient. Here, for the first time in a live surgical setting, we assess the accuracy and technique of a novel imageless semiautonomous handheld robotic surgical technique in bi-cruciate retaining total knee arthroplasty (Navio, Smith and Nephew). The system supports image-free anatomic data collection, intraoperative surgical planning and execution of the plan using a combination of robotic burring and saw cut guides


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_18 | Pages 18 - 18
1 Apr 2013
Lancaster S Robinson J Spalding T Brown C
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There is increasing interest in the placement of the femoral and tibial tunnels for anterior cruciate ligament (ACL) reconstruction, with a trend towards a more anatomically accurate reconstruction. Non-anatomical reconstruction of the ACL has been suggested to be one of the major causes of osteoarthritis in the knee following ACL rupture. Knee surgeons from an international community were invited to demonstrate their method for arthroscopic ACL tunnel placement in an ACL deficient cadaveric knee. These positions were recorded with image intensification and compared with the native ACL insertion sites, which had previously been recorded with image intensification, before the ACL had been resected. Some clear trends were observed; the use of three tunnel placement techniques (anatomic ridges, ‘ruler method’ and use of image intensification) was associated with most accurate position of the femoral tunnel in the centre of the native ACL femoral insertion site. The choice of arthroscopy portals also affected tunnel placement. There is considerable variation in ACL reconstruction tunnel placement amongst experienced knee surgeons. This study provides useful information as to which tunnel placement methods are associated with the most anatomically accurate ACL reconstruction


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_20 | Pages 51 - 51
1 Dec 2017
Cucchi D Compagnoni R Ferrua P Menon A Randelli P
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Patient specific instrumentation (PSI) for total knee arthroplasty (TKA) may improve component position and sizing. However, little has been reported about the accuracy of the default plan created by the manufacturer. The purpose of the study was to evaluate the reliability of the manufacturer plan and the impact of surgeon's changes on the final accuracy of the cutting guide sizes. The planned sizes of 45 TKAs were prospectively recorded from the in the initial manufacturer's proposal and from the final plan modified after surgeon's evaluation and compared to the actually implanted sizes. The manufacturer's initial proposal differed from the final implant in 20% of the femoral and 51.11% of the tibial components, while the surgeon's plan in 13.33% of the femoral and 26.67% of the tibial components. Surgeon's modifications in the pre-operative were carried out for 11.11% of the femoral components and 51.11% of the tibial ones (p = 0.0299). Appropriate modification occurred in of 88% and 76% of femoral and tibial changes respectively. The surgeon's accuracy to predict the final component size was significantly different from that of the manufacturer and changes on the manufacturer's plan were necessary to get an accurate preoperative plan of the implant sizes. Careful evaluation by an experienced knee surgeon is mandatory when planning TKA with PSI. Collaboration between surgeons and manufacturers may help obtain improved accuracy in PSI size planning


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_15 | Pages 66 - 66
1 Aug 2017
Haidukewych G
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There are many challenges facing the revision knee surgeon. Bony defects, ligamentous imbalance, and difficult gap balancing scenarios are common and require practical management strategies. Typically, an implant with the least amount of constraint necessary to provide a well-aligned, well-balanced arc of motion is preferred. Constraint in implants increases the stresses on both the bearing surfaces and the bony interfaces and may result in earlier mechanical failure of the implant. Despite this fact, there are situations where one cannot rely on a simple larger polyethylene post (such as found in CCK type devices) to balance gaps. The author prefers to choose hinge-type devices in situations that demonstrate massive gap imbalance (typically huge flexion gaps), situations with deficient extensor mechanisms that can result in recurvatum stresses, or in situations of global ligamentous instability. Techniques of supporting the bony interfaces with stems and sleeves may improve the longevity of these constructs. Complications are common, including extensor mechanism problems. Multiple studies have demonstrated reasonable results of hinged implants for these challenging revision scenarios, and the hinge should remain in the armamentarium of the revision surgeon


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIX | Pages 242 - 242
1 Sep 2012
Varghese M Ibrahim M Barton S Hopton B
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Introduction. Anterior cruciate ligament (ACL) rupture is a common sporting injury, often managed surgically with patella-tendon or hamstrings autograft. Surgeons are under increasing pressure for open transparent assessment of their performance. Scoring systems can be used to assess outcome. More than 50 different scoring systems have been identified to assess the ACL deficient knee. Aims. The survey is investigating the use of ACL scoring systems between knee surgeons in the United Kingdom as a method of assessing performance. Method. 134 knee surgeons in the United Kingdom, performing ACL reconstruction, were asked to complete a written questionnaire regarding their use of scoring systems & outcome measures. Written questionnaires were sent and responses were received by post. Results. 81 (60%) surgeons responded to the questionnaire by stating their preferred scoring system. 40 (49%) surgeons routinely use ACL scoring systems versus 41 (51%) surgeons who do not. The Lysholm (I and II) knee scoring scale (80%) and Tegner activity score (67.5%) were most commonly used (57.5% both of them) followed by the Knee injury and osteoarthritis outcome score (KOOS) (30%), International Knee Documentation Committee (IKDC) subjective knee score (22.5%), Medical Outcome Study 12 Item Short Form (SF12) (20%), the Medical Outcome Study 36 Item Short Form (SF 36) (12.5%), Cincinnati Knee Scoring System (10%), and ACL Quality of Life scoring system (7.5%). Recommendations. The routine use of ACL scoring systems by 49% of surgeons raises the question - should all surgeons be using scoring systems in their ACL practice? This would be relatively easy to do as most patients are followed up post operatively for 6 months. This will help to adopt a transparent assessment of the performance of every consultant to the procedure they perform


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_7 | Pages 113 - 113
1 Apr 2017
Haidukewych G
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There are many challenges facing the revision knee surgeon. Bony defects, ligamentous imbalance, and difficult gap balancing scenarios are common and require practical management strategies. Typically, am implant with the least amount of constraint necessary to provide a well-aligned, well-balanced arc of motion is preferred. Constraint in implants increases the stresses on both the bearing surfaces and the bony interfaces and may result in earlier mechanical failure of the implant. Despite this fact, there are situations where one cannot rely on a simple larger polyethylene post (such as found in CCK type devices) to balance gaps. The author prefers to choose hinge type devices in situations that demonstrate massive gap imbalance (typically huge flexion gaps), situations with deficient extensor mechanisms that can result in recurvatum stresses, or in situations of global ligamentous instability. Techniques of supporting the bony interfaces with stems and sleeves may improve the longevity of these constructs. Complications are common, including extensor mechanism problems. Multiple studies have demonstrated reasonable results of hinged implants for these challenging revision scenarios, and the hinge should remain in the armamentarium of the revision surgeon


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_10 | Pages 126 - 126
1 Jun 2018
Berend K
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It is a not so uncommon clinical scenario: well-fixed, well-aligned, balanced total knee arthroplasty with continued pain. However, radiographs also demonstrate an unresurfaced patella. The debate continues and the controversy remains as whether or not to routinely resurface the patella in total knee arthroplasty. In perhaps the most widely referenced article on the topic, the overall revision rates were no different between the resurfaced (9%) and the unresurfaced (12%) groups and thus their conclusion was that similar results can be obtained with and without resurfacing. However, a deeper look in to the data in this study shows that 4 times more knees in the unresurfaced group were revised for patellofemoral problems. A more recent study concluded that selectively not resurfacing the patella provided similar results when compared to routinely resurfacing. The study does emphasise however, that this conclusion depends greatly on femoral component design and operative diagnoses. This suggests that selective resurfacing with a so-called “patella friendly” femoral component in cases of tibio-femoral osteoarthritis, is a safe and effective strategy. Finally, registry data would support routine resurfacing with a 2.3 times higher relative risk of revision seen in the unresurfaced TKA. Regardless of which side of the debate one lies, the not so uncommon clinical scenario remains; what do we do with the painful TKA with an unresurfaced patella. Precise and accurate diagnosis of the etiology of a painful TKA can be very difficult, and there is likely a strong bias towards early revision with secondary patellar resurfacing in the painful TKA with an unresurfaced TKA. At first glance, secondary resurfacing is associated with relatively poor outcomes. Correia, et al. reported that only half the patients underwent revision TKA with secondary resurfacing had resolution of their complaints. Similarly, only 53% of patients in another series were satisfied with the procedure and pain relief. The conclusions that can be drawn from these studies and others are that either routine patellar resurfacing should be performed in all TKA or, perhaps more importantly, we need to better understand the etiology of pain in an otherwise well-aligned, well-balanced, well-fixed TKA. It is this author's contingency that the presence of an unresurfaced patella leads surgeons to reoperate earlier, without truly identifying the etiology of pain or dissatisfaction. This strong bias; basically there is something more that can be done, therefore we should do it, is the same bias that leads to early revision of partial knee arthroplasty. While very difficult, we as knee surgeons should not revise a partial knee or secondarily resurface a patella due to pain or dissatisfaction. Doing so, unfortunately, only works about half the time. The diagnostic algorithm for evaluating the painful, uresurfaced TKA includes routinely ruling out infection with serum markers and an aspiration. Pre-arthroplasty radiographs should be obtained to confirm suitability and severity of disease for an arthroplasty. An intra-articular diagnostic injection with Marcaine +/− corticosteroid should provide significant pain relief. MARS MRI may be beneficial to evaluate edema within the patella. Lastly, operative implant stickers to confirm implant manufacturer and type are critical as some implants perform less favorably with unresurfaced patellae. To date, no studies of secondary resurfacing describe the results of this, or similar, algorithms for defining patellofemoral problems in the unresurfaced TKA and therefore it is still difficult to conclude that poor results are not simply due to our inherent bias towards early revision and secondary resurfacing of the unresurfaced patella


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_22 | Pages 86 - 86
1 Dec 2016
Thienpont E
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A majority of patients present with varus alignment and predominantly medial compartment disease. The secret of success in osteoarthritis (OA) treatment is patient selection and patient specific treatment. Different wear patterns have been described and that knowledge should be utilised in modern knee surgery. In case of isolated anteromedial OA, unicompartmental knee arthroplasty (UKA) should be one of the therapeutic options available to the knee surgeon. The discussion not to offer a UKA to patients is based on the fear of the surgeon not being able to identify the right patient and not being able to perform the surgery accurately. The common modes of failure for UKA, which are dislocation or overcorrection leading to disease progression, can be avoided with a fixed bearing implant. Wear can probably be avoided with newer polyethylenes and avoidance of overstuffing in flexion of the knee. Revision for unexplained pain and unknown causes should disappear once surgeons understand persistent pain after surgery much better than they do today. The choice in favor of UKA is a choice of function over survivorship, a choice for reduced comorbidity and lower mortality. Many of the common problems in TKA are not an issue in UKA. Component overhang, decreased posterior offset, changed joint line height, gap mismatch, flexion gap instability, lift off and paradoxical motion hardly exist in UKA if the replacement is performed according to resurfacing principles with respect for the native knee anatomy. New technologies like navigation, PSI and robotics will help with alignment and component positioning. Surgeon education and training should allow over time UKA to be performed by all of us


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_16 | Pages 64 - 64
1 Dec 2015
Williams R Khan W Huntley N Morgan-Jones R
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Joint degeneration may make a total knee arthroplasty (TKA) a requirement for pain relief and function. However, the presence of ipsilateral limb osteomyelitis (OM) makes surgical management extremely challenging. We report the experience of a high volume revision knee surgeon managing ipsilateral limb multi resistant OM and the outcome of subsequent TKA. Four consecutive patients were identified who had either ipsilateral femoral or tibial chronic osteomyelitis treated prior to undergoing TKA. Surgery to eradicate the osteomyelitis involved a Lautenbach compartmental debridement, and where necessary, healing by secondary intention. The decision to proceed to a TKA was based on history, clinical examination and radiological findings of advanced osteoarthritic change. The patients had a mean age of 50 years. They had a background of multi-organism OM and underwent single-stage TKAs at an average of 63 months following eradication of the underlying OM. Three patients did well but had complications associated with poor skin and soft tissues, and abnormal bone anatomy. One patient developed an infection and following a re-revision had an arthrodesis. The results for the four cases are summarised in Table 1. We have highlighted that patients with ipsilateral limb multi resistant OM are a difficult cohort to manage


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_8 | Pages 4 - 4
1 Jun 2015
Akhtar M Bonner T White L Hui A
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Recurrent patellar instability is common in young and active patients. Medial patellofemoral ligament (MPFL) reconstruction with a single bundle hamstring graft is one method of surgical treatment for this problem. This is a retrospective case series of patients who underwent MPFL reconstruction by a single specialist knee surgeon between January 2009 and July 2014. Data was collected prospectively for the purpose of service evaluation. Recorded data included gender, age, length of rehabilitation, complications, Knee Injury and Outcome Score (KOOS) and International Knee Documentation Score (IKDC). Data is expressed as mean (range). 108 knees (103 patients) were identified (56 female, 52 male) with a mean age of 24.5 years (12–58). Mean length of rehabilitation was 3.2 months (0–11 months). Three patients required further revision surgery for recurrent instability. KOOS and IKDC scores improved from 44 (4–86) and 38 (2–81), respectively before surgery, to 77 (49–100) and 69 (37–95) after rehabilitation. MPFL reconstruction with a single bundle hamstring graft produces a marked improvement in knee function with a low recurrence of instability


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_22 | Pages 93 - 93
1 Dec 2016
Cameron H
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Persistent post-surgical pain remains a problem after knee replacement with some studies reporting up to 20% incidence. Pain is usually felt by those who do not operate to be a monolithic entity. All orthopaedic surgeons know that this is not the case. At its most basic level, pain can be divided into two categories, mechanical and non-mechanical. Mechanical pain is like the pain of a fresh fracture. If the patient does not move, the pain is less. This type of pain is relieved by opiates. Mechanical pain is seen following knee replacement, but is fortunately becoming less frequent. It is caused by a combination of malrotations and maltranslations, often minor, which on their own would not produce problems. The combination of them, however, may produce a knee in which there is overload of the extensor mechanism or of the medial stabilizing structures. If these minor mechanical problems can be identified, then corrective surgery will help. Non-mechanical pain is present on a constant basis. It is not significantly worsened by activities. Opiates may make the patient feel better, but they do not change the essential nature of the pain. Non-mechanical pain falls into three broad groups, infection, neuropathic and perceived pain. Infection pain is usually relieved by opiates. Since some of this pain is probably due to pressure, its inclusion in the non-mechanical pain group is questionable, but it is better left there so that the surgeon always considers it. Low grade chronic infection can be extremely difficult to diagnose. Loosening of noncemented knee components is so rare that when it is noted radiologically, infection should be very high on the list of suspicions. The name neuropathic pain suggests that we know much more about it than we do in reality. Causalgia or CRPS-type two is rare following knee replacement. CRPS type one or reflex sympathetic dystrophy probably does exist, but it is probably over-diagnosed especially by the author of this abstract. The optimum treatment I have found is lumbar sympathetic blocks. Perceived pain is the largest group. It does not matter what you tell the patient, some believe a new knee should be like a new car, i.e. you step into it and drive away. The fact that they have to work to make it work is horrifying. Some of this pain is actually mechanical, especially in those with no benefits such as hairstylists. Perceived pain is widespread. The classic treatise on this is Dr. Ian McNabb's book “Backache”. It should be studied by all orthopaedic surgeons, who wish to understand pain complaints. Any experienced knee surgeon will have his list of red flags or caveats. These are often politically incorrect and this information is transferred to young surgeons, usually in dim bars late at night. I will list only a few. If the patient comes in with a form asking for a disability pension on the first visit. If the patient's mother answers the questions. If the patient comes in taking massive doses of opiates. If the patient is referred to you by a surgeon, who does more knee replacements than you do. There is also the recently described Fern Silverman's syndrome


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_1 | Pages 65 - 65
1 Jan 2016
Camillieri G Calvisi V
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Self-locking button-like fixation devices for ACL reconstruction are attracting knee surgeons' attention due to promising technical advantages: complete filling of the tunnel with graft, anatomic reconstruction (AM portal), fixation achievement even when a short tunnel is reamed, opportunity of graft re-tensioning after tibial fixation and/or cyclic load. We compared two similar devices (TightRope vs ToggleLocZL). 20 fresh-frozen porcine femurs (mean age 2.1 years) were assigned to the two groups by randomization. Hamstrings with 9 mm of diameter were obtained using bovine tendons that show the same biomechanic behaviour of human hamstrings. Femoral tunnel was created by AM portal technique (anatomic position). Zwick-Roell z010 tension/compression device with bone and tendon clamps, was used for the study:. Cyclic test (1000 cycles, 0.5 Hz, 50–250 N/cycle, 50 cycles of preload at 10–80 N/cycle). Final pull-out test (1 mm/s). Failure analysis. CT scan and densitometry. Any implant didn't fail during cyclic test. The elongation average was 2.85±1.63 for ToggleLoc and 2.71±.85 for TightRope (P>0.05). Pull-out test showed different values in terms of Ultimate Strength Failure (USF), Stiffness at USF, and Stiffness:. The failure mode was:. The mean method of failure was the fracture of the cortical bone of the femoral condyle, for both groups. But if we extrapolate the USF the difference was favourable(P<0.05) for TightRope (707.83 N) than ToggleLoc (580.16). The mean bone density of porcine femora was comparable to young human femora (1.12±0.31 BMD). The reproducibility of surgical technique, the mechanical strength and endurance of the systems suggest two valid options for ACL reconstruction with hamstring. ToggleLoc showed worse results due to the sharp squared edges of the button


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_16 | Pages 141 - 141
1 Dec 2015
Moore P Kempshall P Gosal H Mutimer J
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The diagnosis of periprosthetic joint infection may be difficult with patients presenting months or years after initial surgery with surgery-associated or haematogenously spread bacteria. Synovasure™ is a new point of care assay that measures alpha defensin produced by activated leucocytes in joints; it is licensed for the diagnosis of periprosthetic joint infections. We sought to include alpha defensin testing in a testing algorithm to improve the diagnosis of periprosthetic joint infection. An algorithm for testing patients with suspected periprosthetic joint infection was developed and agreed among knee surgeons in Gloucestershire, UK. Data was prospectively collected on all tests performed along with information on how the results of the alpha defensin test altered patient management. A sample of joint fluid was taken using aseptic technique in theatre and tested for alpha defensin production at the point of care. Samples were then referred for standard culture and selected samples for 16SrRNA PCR. 12 patients were assayed for alpha defensin in periprosthetic joint fluid during 2015. 7 patients were female, 5 male and ages ranged 64–86 years. 10 patients had a negative point of care alpha defensin test. Only 2 of these patients also had a leukeocyte esterase (LE) test performed and these were negative. The culture results from all samples were negative for both direct and enrichment cultures. 3 samples also had 16SrRNA PCR performed and these were negative. 2 patient samples tested positive for alpha defensin. LE tests were not performed. Both samples were culture negative on direct and enrichment culture however both samples were also referred for 16SrRNA PCR which detected DNA compatible with Staphylococcus caprae/capitis/ saccharolyticus/epidermidis from 1 patient and DNA with homology to Streptococcus gallolyticus/equinusI for the other. Alpha defensin testing improved the diagnosis of prosthetic joint infection. A positive alpha defensin test may be used to select patients for whom 16SrRNA PCR testing is useful in order to maximise the potential for pre-revision infection diagnosis and the planning of appropriate adjuncts such as antibiotic laden cement or calcium sulphate beads. Negative alpha defensin tests on aspirated joint fluid may avoid the need for arthroscopy and biopsy and allow planning for single stage revision surgery without concern for infection


Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_18 | Pages 15 - 15
1 Dec 2014
Thambapillay S Kornicks S Chakrabarty G
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Severe deformity and bone loss in patients with degenerative changes of the knee present a challenging surgical dilemma to the knee surgeon. We present the outcome following complex primary total knee replacements at our unit over 12 years undertaken by a single surgeon. Method:. 65 patients were followed up prospectively with regards to their pre- and post-operative Oxford knee scores, diagnoses, preoperative deformity, bone loss, surgical technique, type of implant used, bone substitutes, and perioperative, or long term complications. These patients were followed up annually. Result:. 70 complex primary total knee replacements were performed in 65 patients. The mean age was 70.5 years and the mean follow up was 62.4 months. Sleeve/wedge augmentation, and stemmed implant (Sigma®TC3- DePuy) were used in general. Bone grafting was utilized for contained bone defects. All except 4 patients were allowed to fully weight bear immediately postoperatively. The mean range of flexion was 112.5 degrees at their last follow up. The mean preoperative Oxford Knee Score was 12.8, and 41.5 postoperatively. 89.4% of patients had either an excellent or good, and the rest a fair outcome. Radiological appearance has been satisfactory in all patients at subsequent follow up, with no evidence of implant loosening. None required revision surgery. 6 patients required blood transfusion postoperatively. 2 patents developed symptomatic deep vein thrombosis and a further 2 had pulmonary embolus. Conclusion:. Our experience with complex primary total knee replacements has been promising with a good outcome


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_17 | Pages 63 - 63
1 Nov 2016
Jones R
Full Access

Persistent post-surgical pain (PPSP) remains a problem after knee replacement with some studies reporting up to 20% incidence. Pain is usually felt by those who do not operate to be a monolithic entity. All orthopaedic surgeons know that this is not the case. At its most basic level, pain can be divided into two categories, mechanical and non-mechanical. Mechanical pain is like the pain of a fresh fracture. If the patient does not move, the pain is less. This type of pain is relieved by opiates. Mechanical pain is seen following knee replacement, but is becoming less frequent. It is caused by a combination of malrotations and maltranslations, often minor, which on their own would not produce problems. The combination of them, however, may produce a knee in which there is overload of the extensor mechanism or of the medial stabilizing structures. If these minor mechanical problems can be identified, then corrective surgery will help. Non-mechanical pain is present on a constant basis. It is not significantly worsened by activities. Opiates may make the patient feel better, but they do not change the essential nature of the pain. Non-mechanical pain falls into three broad groups, infection, neuropathic and perceived pain. Infection pain is usually relieved by opiates. Since some of this pain is probably due to pressure, its inclusion in the non-mechanical pain group is questionable, but it is better left there so that the surgeon always considers it. Low grade chronic infection can be extremely difficult to diagnose. Loosening of noncemented knee components is so rare that when it is noted radiologically, infection should be very high on the list of suspicions. The name neuropathic pain suggests that we know much more about it than we do in reality. Causalgia or CRPS-type two is rare following knee replacement. CRPS-type one or reflex sympathetic dystrophy probably does exist, but it is probably over-diagnosed. The optimum treatment I have found is lumbar sympathetic blocks. Lyrica, Gabapentin and Cymbalta may also help. Perceived pain is the largest group. It does not matter what you tell the patient, some believe a new knee should be like a new car, i.e. you step into it and drive away. The fact that they have to work to make it work is horrifying. Perceived pain is widespread. The classic treatise, Dr. Ian McNabb's book “Backache”, should be studied by all who wish to understand pain complaints. Any experienced knee surgeon will have his list of red flags or caveats. I will list only a few. If the patient comes in with a form asking for a disability pension on the first visit. If the patient's mother answers the questions. If the patient comes in taking massive doses of opiates. If the patient is referred to you by a surgeon who does more knee replacements than you do. There are other issues such as good old fibromyalgia, which appears to have gone the way of the dodo. It has been replaced by something equally silly called central sensitization. The theory of central sensitization is that if one has pain somewhere or other for three months or six months or whatever, there are going to be changes in the brain and spinal cord. It then does not matter what happens to the original pain, i.e. whether or not it goes away, the pain will persist because of the changes in the brain, hence, the title of the pain in the brain syndrome. If this theory was correct, we might as well all go home because we have all been wasting our time for the last 30 years because none of our patients would get any better. After all, all of our patients have had pain for a lot longer than three months, many of them have been involved in trauma and sometimes, compensation is at issue. The pain in the brain theory, therefore, sounds about as realistic as the flat earth society or the treatment of Galileo


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_1 | Pages 103 - 103
1 Jan 2016
D'Lima D Patil S Bunn A Colwell C
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Background. Despite the success of total knee arthroplasty (TKA) restoration of normal function is often not achieved. Soft tissue balance is a major factor for poor outcomes including malalignment, instability, excessive wear, and subluxation. Computer navigation and robotic-assisted systems have increased the accuracy of prosthetic component placement. On the other hand, soft tissue balancing remains an art, relying on a qualitative feel for the balance of the knee, and is developed over years of practice. Several instruments are available to assist surgeons in estimating soft tissue balance. However, mechanical devices only measure the joint space in full extension and at 90° flexion. Further, because of lack of comprehensive characterization of the ligament balance of healthy knees, surgeons do not have quantitative guidelines relating the stability of an implanted to that of the normal knee. This study measures the ligament balance of normal knees and tests the accuracy of two mechanical distraction instruments and an electronic distraction instrument. Methods. Cadaver specimens were mounted on a custom knee rig and on the AMTI VIVO which replicated passive kinematics. A six-axis load cell and an infrared tracking system was used to document the kinematics and the forces acting on the knee. Dynamic knee laxity was measured under 10Nm of varus/valgus moment, 10Nm of axial rotational moment, and 200N of AP shear. Measurements were repeated after transecting the anterior cruciate ligament, after TKA, and after transecting the posterior cruciate ligament. The accuracy and reproducibility of two mechanical and one electronic distraction device was measured. Results. The maximum passive varus laxity measured over the range of flexion was 6.4°(±2.0) and maximum passive valgus laxity was 2.6°(±0.7), (p < 0.05). The maximum passive rotational laxity measured was 9.0°(±0.57) for internal and 14.1°(±1.6) for external rotation (p < 0.05). Average stiffness of the knee (Nm/deg) was 1.7 (varus), 2.4 (valgus), 0.8 (internal rotation), and 0.5 (external rotation). The difference in tibiofemoral gap between flexion and extension was 2.9mm (±1.6). The stiffness of the mechanical and electronic distractors was very linear over a distraction range of 0 to 6mm. At forces ranging from 40N to 120N, the accuracy and repeatability of the mechanical distractors was within 1mm, and that of the dynamic electronic distractor was 0.2mm. The electronic distractor measured the varus of the tibial cut and the distal femoral cut within 0.5°, and the rotation of the posterior femoral cut within 0.7° of surgical navigation measurements. Conclusions. The dynamic electronic distraction device was significantly more accurate than mechanical instruments and measured knee balance over the entire range of flexion. The stiffness of the normal knee was distinctly different in varus and valgus. The standard recommendation for equal medial and lateral gaps under distraction may have to be revisited. Combining implant design improvements with sophisticated balancing instruments is likely to make a significant impact on improving function after total knee arthroplasty


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIX | Pages 86 - 86
1 Sep 2012
Azam A Agarwal S Morgan-Jones R
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Introduction. This study was undertaken to evaluate the early results of a new implant system - the metaphyseal sleeve - in revision total knee replacement. The femoral and tibial metaphyseal sleeves are a modular option designed to deal with metaphyseal bone loss and achieve cementless fixation over a relatively wide area in the metaphysis. Methods. Over three years, femoral and/or tibial metaphyseal sleeves were implanted in 104 knees in 103 patients (54 male and 49 female). The clinical notes and radiographs of these patients were reviewed retrospectively. Thirty one patients had revision for infection, 42 for aseptic loosening, and 31 for instability, pain or stiffness. Eighty nine knees were revised as a single stage and 15 were done as two stage procedure. Minimum follow up is 12 months (average 18.5 months). Results. At the time of final follow up the sleeves showed good osseointegration in 102 knees with no evidence of loosening or subsidence. In two knees, a progressive radiolucency was noted around the metaphyseal sleeve 6 months after the revision procedure. Both these patients were symptomatic. The inflammatory markers were raised and Tc-99 bone scan showed increased uptake in the delayed phase. Loosening of the sleeve was confirmed on CT scans. SPECT scan raised suspicion of focal infection around the sleeve in one patient. Conclusion. The early results with the use of metaphyseal sleeves are encouraging. The sleeves provided firm fixation and structural support in patient with significant metaphyseal bone loss. This obviated the need for metal augments or bone graft. Further follow up will be required to evaluate the medium and long term results of this option. We believe the addition of cementless metaphyseal fixation is a useful tool in the armamentarium of the revision knee surgeon


Introduction. It is widely accepted that computer navigation more reliably restores neutral mechanical alignment than conventional instrumentation in total knee arthroplasty (TKA) surgery. Recently, magnetic resonance (MR) based instrumentation has been introduced to the market with a rapid growth in usage. However, a paucity of comparative data still exists on the precision of magnetic resonance (MR) based instruments in achieving acceptable lower limb alignment when compared to other validated techniques. In this analysis, we compare the radiographic outcomes of 3 techniques to achieve satisfactory prosthetic alignment by 2 surgeons using the same prosthesis and surgical technique. Methods. A series of 180 patients who had undergone TKA surgery were included in this study. Two fellowship-trained knee surgeons performed all surgeries using the same cemented, posterior stabilized implants (NexGen, Zimmer, Warsaw, In). Patients were stratified in to 3 groups according to the technique used to align the knee; 1. Conventional Intra-medullary Instrumentation, 2. Computer Navigation (Orthosoft), and 3. MR-based guides (Zimmer PSI). All patients underwent a post-operative CT Perth Protocol to assess coronal, sagittal and rotational alignment of the femoral and tibial implants. A radiographer who was blinded to the alignment technique used performed all radiographic measurements. Outliers were defined at a deviation of more than 3 degrees from the mechanical axis in all planes of motion. Results. The radiographic outcome measures will be presented to highlight the significant differences between 3 groups. In addition, the early surgical experience with the introduction of MR based instruments will be reviewed along with the early problems encountered from tibial sagittal alignment that became apparent with time. Conclusion. The rapid introduction of MR based instruments in to the market by several prosthetic companies has occurred without adequate pre-release analysis. This study will allow surgeons to make an informed decision on whether to use this technology based on validated radiographic measures, when compared to both conventional alignment techniques and computer navigation


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIV | Pages 27 - 27
1 Jul 2012
Henderson L Johnston A Stokes M Corry I Nicholas R
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Anterior cruciate ligament (ACL) reconstruction is a commonly performed operation. A variety of graft options are used with the most popular being bone-patellar-tendon-bone and hamstring autograft. There has been an increase in the popularity of hamstring autograft over the past decade. The aim of the study was to assess the ten year subjective knee function and activity level following four-strand semitendinosis and gracilis (STG) anterior cruciate ligament reconstruction. 86 patients underwent anterior cruciate reconstruction by two knee surgeons over a 12 month period (January 1999 to December 1999). 80 patients meet the inclusion criteria of arthroscopic ACL reconstruction. The same surgical technique was used by both surgeons involving four-strand STG autograft, single femoral and tibial tunnels and aperture graft fixation with the Round headed Cannulated Interference (RCI) screw. Patient evaluation was by completion of a Lysholm Knee Score and Tegner Activity Level Scale at a minimum of ten years from reconstructive surgery. This was by initial postal questionnaire and subsequent telephone follow-up. 80 patients underwent anterior cruciate reconstruction with average age 30.9 years (15 to 58 years). There was a 77.5% (62 patients) response at ten years to the questionnaire. The median Lysholm Knee Score at ten years was 94 (52 to 100). The median activity level had decreased from 9 to 5 at ten years according to the Tegner Activity Scale. 73% of patients reported a good or excellent outcome on the Lysholm score. The group of patients was further divided into those that required meniscal surgery and those that did not. The patients that did not require meniscal surgery had a median Lysholm score of 94 and those that required meniscal surgery had a similar median Lysholm score of 92.5. However it was noted that 8 patients required medial and lateral partial menisectomies at the time of original reconstruction. This group of patients had a median Lysholm Knee Score of 83.5 and Tegner Activity Scale of 4 at ten years following reconstruction. 17 of the 62 patients (27.4%) required re-operation because of further knee symptoms, with 4 patients requiring revision of the anterior cruciate following re-rupture. In conclusion anterior cruciate ligament reconstruction with four-strand STG hamstring autograft provides a reliable method of restoring knee function, with a 6% revision rate for re-rupture at ten years. Combined partial medial and lateral menisectomy at the time of the initial reconstruction is a poor prognostic indicator of function at ten years