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Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_10 | Pages 15 - 15
1 May 2017
Poyton R Cowell I Hall T Drew P Murtagh G McGregor A
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Background. Persistent low back and leg pain is a common and highly disabling musculoskeletal condition. Many patients seek the opinion of a neurosurgeon with a view to surgical intervention. Few data are available which document the experiences of patients at these consultations. Aims. To investigate the experiences of patients seeking a neurosurgical opinion for back and leg pain. Methods. 15 patients (Males 9 Females 6) were consented and recruited into this study and participated in an in-depth semi-structured interview about their experiences of the consultation. Interviews were recorded and transcribed. Transcribed data were read independently by two researchers and analysed using grounded theory. Results. Three subgroups of patients were identified from the interviews. Group 1: Patients that were offered surgery and described a positive experience. Group 2: Patients that were not offered surgery and described a positive experience. Group 3: Patients that were not offered surgery and described a negative experience. Analysis revealed a number of different themes pertaining to the experiences of each group. However, two overarching themes of i) meeting patients' expectations and ii) the factor of hope, emerged as significant contributors to their experience and were evident in all three subgroups. Conclusion. Findings identified the need to manage patient expectations in the consultation in order to provide a positive experience. Providing patients with hope who are not undergoing surgery, but who have an expectation for it, is likely to provide a more positive experience and therefore increased satisfaction with care. No conflicts of interest. Part funded by North East London Foundation Trust


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_2 | Pages 24 - 24
1 Feb 2018
Ely S Stynes S Ogollah R Foster N Konstantinou K
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Background. Criticisms about overuse of MRI in low back pain are well documented. Yet, with the exception of suspicion of serious pathology, little is known about factors that influence clinicians' preference for MRI. We investigated the factors associated with physiotherapists' preference for MRI for patients consulting with benign low back and leg pain (LBLP) including sciatica. Methods. Data were collected from 607 primary care patients consulting with LBLP and assessed by 7 physiotherapists, in the ATLAS cohort study. Following clinical assessment, physiotherapists documented whether he/she wanted the patient to have an MRI. Factors potentially associated with clinicians' preference for imaging were selected a priori, from patient characteristics and clinical assessment findings. A mixed-effect logistic regression model examined the associations between these factors and physiotherapists' preference for MRI. Results. Physiotherapists expressed a preference for MRI in 32% (196/607) of patients, of whom 22 did not have a clinical diagnosis of sciatica (radiculopathy). Factors associated with preference for MRI included; clinical diagnosis of sciatica (OR 4.23: 95% CI 2.29,7.81), greater than 3 months pain duration (OR 2.61: 95% CI 1.58,4.30), high pain intensity (OR 1.24: 95%CI 1.11,1.37), patient's low expectation of improvement (OR 2.40: 95% 1.50,3.83), physiotherapist's confidence in the diagnosis (OR 1.19: 95% CI 1.07,1.33) with greater confidence associated with higher probability of preference for MRI. Conclusion. A clinical diagnosis of sciatica and longer symptom duration were most strongly associated with physiotherapists' preference for MRI. Given current best practice guidelines, these appear to be justifiable reasons for wanting patients to have an MRI. Conflicts of interest: None. Funding. SE was supported through an NIHR internship linked to an NIHR Research Professorship awarded to NEF (RP-01-015). NEF is an NIHR Senior Investigator. KK is supported through a HEFCE Senior Clinical Lecturer award. The views and opinions expressed therein are those of the authors and do not necessarily reflect those of the NIHR, NHS or the Department of Health


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_2 | Pages 6 - 6
1 Feb 2015
Konstantinou K Dunn K Ogollah R Hay E
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Background. 60% of back pain patients report pain radiation in the leg(s), which is associated with worse symptoms and poorer recovery. The majority are treated in primary care, but detailed information about them is scarce. The objective of this study is to describe the characteristics of patients with back and leg pain-seeking treatment in primary care. Methods. Adult patients consulting their GP with back and leg pain were invited to the study. Participants completed questionnaires including sociodemographic, physical and psychosocial measures. They also underwent standardised clinical assessments by physiotherapists, and received an MRI scan. Results. 609 patients participated with 67.5% reporting pain below the knee. 62.6% were female, sample mean (SD) age 50.2 (13.9). 367 (60.7%) were in paid employment with 39.7% reporting time off work. Mean disability (RMDQ) was 12.7 (5.7) and mean pain intensity was 5.6 (2.2) and 5.2 (2.4) for back and leg respectively. Mean sciatica bothersomeness index (SBI) score was 14.9 (5.1). 74.2% (452/609) were clinically diagnosed as having sciatica. Patients in the sciatica group reported significantly higher levels of leg pain and SBI scores, leg pain worse than back pain and pain below the knee. Neuropathic pain was more prevalent in patients with referred leg pain. Conclusion. This primary care cohort reported high levels of disability and pain. Three quarters were diagnosed with sciatica. Follow-up of this cohort will investigate the prognostic value of their baseline characteristics. This abstract summarises independent research funded by the National Institute for Health Research (NIHR) under its Programme Grants for Applied Research Programme (Grant Reference Number RP-PG-0707-10131). The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health. This abstract has not been previously published in whole or substantial part nor has it been presented previously at a national meeting. Conflicts of interest: No conflicts of interest. K. Konstantinou is supported by a HEFCE/NIHR Senior Clinical Lectureship. KM Dunn is supported by the Wellcome Trust (083572)


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_I | Pages 27 - 27
1 Jan 2012
Buisson Y Catley M Lopez JG McGregor A Strutton P
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Introduction

Changes in the central nervous system (CNS) pathways controlling trunk and leg muscles in patients with low back pain and radiculopathy have been observed and this study investigated whether surgery impacts upon these changes.

Methods

Parameters of corticospinal control were examined on 3 occasions in 22 patients prior to, at 6 and 26 weeks following lumbar decompression surgery and in 14 control subjects at the same intervals. Electromyographic activity was recorded from tibialis anterior (TA), soleus (SOL), rectus abdominis (RA), external oblique (EO) and erector spinae (ES) muscles at the T12 & L4 levels in response to transcranial magnetic stimulation of the motor cortex.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 487 - 487
1 Nov 2011
Ali I Ulbricht C McGregor A
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Increasing attention has focused on the spinal muscles with respect to stability and low back pain (LBP) with suggestions of a de-conditioning syndrome. What is less clear is the extent of this degeneration and whether it is a long term of short term consequence of LBP. This study sought to explore the cross section area (CSA) and muscle quality of the spinal extensor group in a subset of LBP patients.

MRI scans of 100 spinal clinic patients were retrospectively reviewed; sagittal and transverse (from levels L3-5) images were annoymised and archived along with details of age, gender and presenting symptoms. An image analysis package was used to determine CSA of the extensor muscle groups, and levels of fat infiltration were calculated using a pseudocolouring technique.

46 patients had spinal stenosis (28 males, 18 females, mean age 66±14.2 years) and 54 had a disc prolapse (28 males, 26 females, mean age 50±12.9 years). CSA was significantly smaller in the stenotics at both L3/4 and L4/5. Patients presenting with leg pain and a disc herniation had a significantly smaller CSA (p< 0.01) at L3/4 and L4/5 levels. A left right CSA asymmetry was noted but this was not specific to diagnosis, or presenting symptoms. Fat infiltration was present in both groups but was significantly greater in the stenotic group (p< 0.01) and was present at a similar degree at all spinal levels. Multiple regression analysis confirmed that reduced CSA was linked to leg pain (p< 0.01) and age was linked with fat infiltration (0< 0.01).

Conflict of Interest: None

Source of Funding: None


Aims. To provide normative data that can assess spinal-related disability and the prevalence of back or leg pain among adults with no spinal conditions in the UK using validated questionnaires. Methods. A total of 1,000 participants with equal sex distribution were included and categorized in five age groups: 20 to 29, 30 to 39, 40 to 49, 50 to 59, and 60 to 69 years. Individuals with spinal pathologies were excluded. Participants completed the Scoliosis Research Society-22 (SRS-22r), visual analogue scale (VAS) for back/leg pain, and the EuroQol five-dimension index (EQ-5D/VAS) questionnaires, and disclosed their age, sex, and occupation. They were also categorized in five professional groups: doctors, nurses, allied health professionals, office workers, and manual workers. Results. The mean age of all participants was 43.8 years (20 to 69). There was no difference in the SRS-22r, EQ-5D, or VAS scores among male and female participants (p > 0.05). There was incremental decrease in SRS-22r total scores as the age increased. The mean EQ-5D index score (0.84) ranged little across the age groups (0.72 to 0.91) but reduced gradually with increasing age. There was difference between the SRS-22r total score (4.51), the individual domain scores, and the EQ-5D score (index: 0.94 and VAS: 89) for the doctors’ group compared to all other occupational categories (p < 0.001). Doctors had a younger mean age of participants, which may explain their improved spinal health. There was no difference in the total or sub-domain SRS-22r and EQ-5D scores between the other four occupational groups. Conclusion. This study provides the first normative data for the SRS-22r, EQ-5D, and VAS for back/leg pain questionnaires among adults in the UK. We recorded an excellent correlation between the three assessment tools with individuals who reported less back and leg pain having better quality of life and greater function. The participants’ age, rather than their sex or profession, appears to be the major determinant for spinal health and quality of life. Cite this article: Bone Jt Open 2022;3(2):130–134


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_II | Pages 118 - 118
1 Jul 2002
Brown RR Bull T
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Objective scoring techniques for back pain are increasingly being used both in the pre-operative selection of patients and as a post-operative outcome measure. Our aim was to determine the strength of correlation between three main scoring techniques used to quantify the severity of the back or leg pain on presentation to a chronic back pain clinic. The Oswestry Disability Index (ODI), the Medical Outcomes Study 36 item Short Form Health Survey (SF36), and the Visual Analogue Scale (VAS) were competed by 130 patients between July and December 1999. There were 65 males and 65 females with the mean age of 49 years. The patients were divided into three groups: with back pain only, sciatic leg pain only, and those with both. The correlation was analysed using the Pearson correlation test. There was a good correlation between the Oswestry Disability Index and Visual Analogue Scale for patients with back pain (r=0.641, p< 0.001) and with sciatic leg pain (r=0.469, p< .001). The physical component of the SF36 strongly correlates with the VAS in back pain (r=0.364) and sciatic leg pain (r=1). However there is a poor correlation between the ODI and VAS and all other components of the SF36


The Bone & Joint Journal
Vol. 106-B, Issue 7 | Pages 705 - 712
1 Jul 2024
Karlsson T Försth P Öhagen P Michaëlsson K Sandén B

Aims. We compared decompression alone to decompression with fusion surgery for lumbar spinal stenosis, with or without degenerative spondylolisthesis (DS). The aim was to evaluate if five-year outcomes differed between the groups. The two-year results from the same trial revealed no differences. Methods. The Swedish Spinal Stenosis Study was a multicentre randomized controlled trial with recruitment from September 2006 to February 2012. A total of 247 patients with one- or two-level central lumbar spinal stenosis, stratified by the presence of DS, were randomized to decompression alone or decompression with fusion. The five-year Oswestry Disability Index (ODI) was the primary outcome. Secondary outcomes were the EuroQol five-dimension questionnaire (EQ-5D), visual analogue scales for back and leg pain, and patient-reported satisfaction, decreased pain, and increased walking distance. The reoperation rate was recorded. Results. Five-year follow-up was completed by 213 (95%) of the eligible patients (mean age 67 years; 155 female (67%)). After five years, ODI was similar irrespective of treatment, with a mean of 25 (SD 18) for decompression alone and 28 (SD 22) for decompression with fusion (p = 0.226). Mean EQ-5D was higher for decompression alone than for fusion (0.69 (SD 0.28) vs 0.59 (SD 0.34); p = 0.027). In the no-DS subset, fewer patients reported decreased leg pain after fusion (58%) than with decompression alone (80%) (relative risk (RR) 0.71 (95% confidence interval (CI) 0.53 to 0.97). The frequency of subsequent spinal surgery was 24% for decompression with fusion and 22% for decompression alone (RR 1.1 (95% CI 0.69 to 1.8)). Conclusion. Adding fusion to decompression in spinal stenosis surgery, with or without spondylolisthesis, does not improve the five-year ODI, which is consistent with our two-year report. Three secondary outcomes that did not differ at two years favoured decompression alone at five years. Our results support decompression alone as the preferred method for operating on spinal stenosis. Cite this article: Bone Joint J 2024;106-B(7):705–712


The Bone & Joint Journal
Vol. 103-B, Issue 1 | Pages 131 - 140
1 Jan 2021
Lai MKL Cheung PWH Samartzis D Karppinen J Cheung KMC Cheung JPY

Aims. To study the associations of lumbar developmental spinal stenosis (DSS) with low back pain (LBP), radicular leg pain, and disability. Methods. This was a cross-sectional study of 2,206 subjects along with L1-S1 axial and sagittal MRI. Clinical and radiological information regarding their demographics, workload, smoking habits, anteroposterior (AP) vertebral canal diameter, spondylolisthesis, and MRI changes were evaluated. Mann-Whitney U tests and chi-squared tests were conducted to search for differences between subjects with and without DSS. Associations of LBP and radicular pain reported within one month (30 days) and one year (365 days) of the MRI, with clinical and radiological information, were also investigated by utilizing univariate and multivariate logistic regressions. Results. Subjects with DSS had higher prevalence of radicular leg pain, more pain-related disability, and lower quality of life (all p < 0.05). Subjects with DSS had 1.5 (95% confidence interval (CI) 1.0 to 2.1; p = 0.027) and 1.8 (95% CI 1.3 to 2.6; p = 0.001) times higher odds of having radicular leg pain in the past month and the past year, respectively. However, DSS was not associated with LBP. Although, subjects with a spondylolisthesis had 1.7 (95% CI 1.1 to 2.5; p = 0.011) and 2.0 (95% CI 1.2 to 3.2; p = 0.008) times greater odds to experience LBP in the past month and the past year, respectively. Conclusion. This large-scale study identified DSS as a risk factor of acute and chronic radicular leg pain. DSS was seen in 6.9% of the study cohort and these patients had narrower spinal canals. Subjects with DSS had earlier onset of symptoms, more severe radicular leg pain, which lasted for longer and were more likely to have worse disability and poorer quality of life. In these patients there is an increased likelihood of nerve root compression due to a pre-existing narrowed canal, which is important when planning surgery as patients are likely to require multi-level decompression surgery. Cite this article: Bone Joint J 2021;103-B(1):131–140


The Bone & Joint Journal
Vol. 103-B, Issue 9 | Pages 1464 - 1471
1 Sep 2021
Barker TP Steele N Swamy G Cook A Rai A Crawford R Lutchman L

Aims

Cauda equina syndrome (CES) can be associated with chronic severe lower back pain and long-term autonomic dysfunction. This study assesses the recently defined core outcome set for CES in a cohort of patients using validated questionnaires.

Methods

Between January 2005 and December 2019, 82 patients underwent surgical decompression for acute CES secondary to massive lumbar disc prolapse at our hospital. After review of their records, patients were included if they presented with the clinical and radiological features of CES, then classified as CES incomplete (CESI) or with painless urinary retention (CESR) in accordance with guidelines published by the British Association of Spinal Surgeons. Patients provided written consent and completed a series of questionnaires.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_I | Pages 5 - 5
1 Jan 2012
Konstantinou K Hider S Jordan J Lewis M Dunn K Hay E
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Purpose and background. Although low back pain (LBP) with leg pain, is considered by most a poor prognostic indicator, it is at the same time believed to have a favourable natural resolution, and is often treated along similar lines to non-specific LBP, in line with current guidelines. It is unclear whether patients with LBP and leg pain are a distinct subgroup that might benefit from early identification and targeted interventions. We set out to investigate the impact of LBP with leg pain on health outcomes and health resources compared with that of LBP alone, and to explore which factors contribute to the observed disability outcomes. Methods. A systematic literature search of all English language peer reviewed publications was conducted using Medline, EMBASE, and CINAHL for the years 1994 to 2009. Results. Of the 89 papers retrieved, 9 were included in the review. The heterogeneity of data allowed only for narrative analysis of findings. All studies reported worsening baseline health status in terms of poorer self-assessment and increasing use of health care the further the radiation of leg pain. Differences in quality of life measures were higher for physical than for mental health dimensions. Pain and disability outcome at follow up assessment appeared to be less favourable in this group than for individuals with LBP alone. Conclusion. LBP with leg pain is associated with poorer health outcomes and increased use of health resources. These findings argue for early identification of these cases by health care professionals and for pursuing effective treatments rather than simply treating similarly to non-specific LBP


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_3 | Pages 41 - 41
1 Mar 2021
Beauchamp-Chalifour P Street J Flexman A Charest-Morin R
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Frailty has been shown to be a risk predictor for peri-operative adverse events (AEs) in patients undergoing various type of spine surgery. However, its relationship with Patient Related Outcome Measures (PROMS) remains unknown. The primary objective of this study was to determine the impact of frailty on PROMS in patients undergoing surgery for thoraco-lumbar degenerative conditions. The secondary objective was to determine the association between frailty and baseline PROMS. This is a retrospective study of a prospective cohort of patients >55 years old who underwent surgery between 2012 and 2018. Patient data and PROMS (EQ-5D, SF-12, ODI, back and leg pain NRS) were extracted from the Canadian Spine Outcomes and Research Network registry for a single academic centre. Frailty was retrospectively calculated using the modified frailty index (mFI) and patient were classified as frail, pre-frail and non-frail. Patient characteristics and outcomes were analyzed using ANOVA or Kruskal-Wallis test for continuous variables and Chi square or Fisher's exact test for proportions. A generalized estimating equations (GEEs) regression model was used to assess the association between patients' baseline frailty status and PROMs measures at three and 12 months. 293 patients were included with a mean age of 67 ± 7 years. Twenty-two percent of the patients (n= 65) were frail, 59 % (n=172) were pre-frail and 19% (n=56) were non-frail. At baseline, the three groups had similar PROMS, except for the PCS which was worse in the frail group (mean difference [95% CI], −4.9 [−8.6;-1.1], p= 0.0083). The improvement in the EQ-5D, PCS, MCS, ODI, back and leg pain NRS scores was not significantly different between the three groups (p> 0.05). The was no difference in the evolution of the PROMS at three and 12 months between the three groups (p> 0.05). Although frailty is a known predictor of AEs, it does not predict worse PROMS after spine surgery in that population. At baseline, non-frail, pre-frail and frail patients have similar PROMS


The Bone & Joint Journal
Vol. 104-B, Issue 2 | Pages 265 - 273
1 Feb 2022
Mens RH Bisseling P de Kleuver M van Hooff ML

Aims. To determine the value of scoliosis surgery, it is necessary to evaluate outcomes in domains that matter to patients. Since randomized trials on adolescent idiopathic scoliosis (AIS) are scarce, prospective cohort studies with comparable outcome measures are important. To enhance comparison, a core set of patient-related outcome measures is available. The aim of this study was to evaluate the outcomes of AIS fusion surgery at two-year follow-up using the core outcomes set. Methods. AIS patients were systematically enrolled in an institutional registry. In all, 144 AIS patients aged ≤ 25 years undergoing primary surgery (median age 15 years (interquartile range 14 to 17) were included. Patient-reported (condition-specific and health-related quality of life (QoL); functional status; back and leg pain intensity) and clinician-reported outcomes (complications, revision surgery) were recorded. Changes in patient-reported outcome measures (PROMs) were analyzed using Friedman’s analysis of variance. Clinical relevancy was determined using minimally important changes (Scoliosis Research Society (SRS)-22r), cut-off values for relevant effect on functioning (pain scores) and a patient-acceptable symptom state (PASS; Oswestry Disability Index). Results. At baseline, 65 out of 144 patients (45%) reported numerical rating scale (NRS) back pain scores > 5. All PROMs significantly improved at two-year follow-up. Mean improvements in SRS-22r function (+ 1.2 (SD 0.6)), pain (+ 0.6 (SD 0.8)), and self-image (+ 1.1 (SD 0.7)) domain scores, and the SRS-22r total score (+ 0.5 (SD 0.5)), were clinically relevant. At two-year follow-up, 14 out of 144 patients (10%) reported NRS back pain > 5. Surgical site infections did not occur. Only one patient (0.7%) underwent revision surgery. Conclusion. Relevant improvement in functioning, condition-specific and health-related QoL, self-image, and a relevant decrease in pain is shown at two-year follow-up after fusion surgery for AIS, with few adverse events. Contrary to the general perception that AIS is a largely asymptomatic condition, nearly half of patients report significant preoperative back pain, which reduced to 10% at two-year follow-up. Cite this article: Bone Joint J 2022;104-B(2):265–273


The Bone & Joint Journal
Vol. 97-B, Issue 11 | Pages 1546 - 1554
1 Nov 2015
Kim HJ Park JW Chang BS Lee CK Yeom JS

Pain catastrophising is an adverse coping mechanism, involving an exaggerated response to anticipated or actual pain. The purpose of this study was to investigate the influence of pain ‘catastrophising’, as measured using the pain catastrophising scale (PCS), on treatment outcomes after surgery for lumbar spinal stenosis (LSS). A total of 138 patients (47 men and 91 women, mean age 65.9; 45 to 78) were assigned to low (PCS score < 25, n = 68) and high (PCS score ≥ 25, n = 70) PCS groups. The primary outcome measure was the Oswestry Disability Index (ODI) 12 months after surgery. Secondary outcome measures included the ODI and visual analogue scale (VAS) for back and leg pain, which were recorded at each assessment conducted during the 12-month follow-up period. The overall changes in the ODI and VAS for back and leg pain over a 12-month period were significantly different between the groups (ODI, p < 0.001; VAS for back pain, p < 0.001; VAS for leg pain, p = 0.040). The ODI and VAS for back and leg pain significantly decreased over time after surgery in both groups (p < 0.001 for all three variables). The patterns of change in the ODI and VAS for back pain during the follow-up period significantly differed between the two groups, suggesting that the PCS group is a potential treatment moderator. However, there was no difference in the ODI and VAS for back and leg pain between the low and high PCS groups 12 months after surgery. . In terms of minimum clinically important differences in ODI scores (12.8), 22 patients (40.7%) had an unsatisfactory surgical outcome in the low PCS group and 16 (32.6%) in the high PCS group. There was no statistically significant difference between the two groups (p = 0.539). . Pre-operative catastrophising did not always result in a poor outcome 12 months after surgery, which indicates that this could moderate the efficacy of surgery for LSS. Cite this article: Bone Joint J 2015;97-B:1546–54


Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_20 | Pages 15 - 15
12 Dec 2024
Drake B Purushothaman B
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Objectives. Sacroiliac joint dysfunction is a degenerative condition that can result in low back pain and is likely underdiagnosed. Diagnosis is made clinically with the patient experiencing pain in the sacroiliac joint region. Initial management is non-operative with pain management, physiotherapy, injections, and rhizolysis. If these fail then surgical management, by sacroiliac joint fusion, can be considered. The aim of this study was to review the outcomes of all patients who underwent sacroiliac joint fusion by a single surgeon in a large district general hospital between April 2018 and April 2023. Design and Methods. A retrospective review of all patients who underwent sacroiliac joint fusion between April 2018 and April 2023 was conducted. Data was collected from clinical letters, operative notes, and the British Spinal Registry. Oswestry Disability Index (ODI) and Visual Analogue Scale (VAS) for back and leg pain were recorded as well as any post-operative complications. Results. In total 19 patients underwent sacroiliac joint fusion. Mean age was 47 years (range 27 – 69 years). Nine were right sided procedures and ten were left. The mean BMI was 32.3. ODI improved from a mean of 55 pre-operative to 26 at one year and 15 at two years post-operative. VAS for back pain improved from a mean of six pre-operative to three at one year and one at two years post-operative. VAS for leg pain improved from a mean of five pre-operative to four at one year and zero at two years post-operative. There were no surgical site complications. One patient developed trochanteric bursitis post-operatively. Two patients have since undergone sacroiliac joint fusion on the contralateral side with a further patient awaiting contralateral surgery. Conclusion. In patients with sacroiliac joint pain where non-operative measures have failed to control symptoms sacroiliac joint fusion is a reliable and effective surgical option


The Journal of Bone & Joint Surgery British Volume
Vol. 93-B, Issue 11 | Pages 1518 - 1523
1 Nov 2011
Lakkol S Bhatia C Taranu R Pollock R Hadgaonkar S Krishna M

Recurrence of back or leg pain after discectomy is a well-recognised problem with an incidence of up to 28%. Once conservative measures have failed, several surgical options are available and have been tried with varying degrees of success. In this study, 42 patients with recurrent symptoms after discectomy underwent less invasive posterior lumbar interbody fusion (LI-PLIF). Clinical outcome was measured using the Oswestry Disability Index (ODI), Short Form 36 (SF-36) questionnaires and visual analogue scales for back (VAS-BP) and leg pain (VAS-LP). There was a statistically significant improvement in all outcome measures (p < 0.001). The debate around which procedure is the most effective for these patients remains controversial. Our results show that LI-PLIF is as effective as any other surgical procedure. However, given that it is less invasive, we feel that it should be considered as the preferred option


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 282 - 282
1 May 2009
Karppinen J Daavittila I Noponen N Männikkö M Haapea M Taimela S Vanharanta H Ala-Kokko L
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Introduction: We have shown that an IL6 haplotype (GGGA) associates with intervertebral disc disease (IDD) characterized by sciatica. However, its prognostic value for IDD is not known. Materials and methods: DNA from 153 sciatica patients, who participated in a randomized controlled trial of periradicular infiltration, was analyzed for IL6 variations: c.1–597G> A, c.1–572G> C, c.1–174G> C, and c.486T> A (Genebank #NM_000600.1). Patients recorded back and leg pain intensity and duration (number of days with pain), Oswestry disability, and back-related sick leaves. Repeated measures ANCOVA with adjustment for age, gender and physical work load was used. Square root transformations of outcome data at one, two and three years after the intervention were used for skewed variables. Results: The prevalence of the GGGA haplotype was 9% (14/153). Data was available from 10 (sick leaves) to 13 (VAS) subjects with and from 107 to 124 subjects without the haplotype. The groups did not differ with respect to pain intensities, or disability. Days with back and leg pain and sick leaves were significantly higher among subjects with the IL6 haplotype (p=0.024, 0.002 and 0.022, respectively). An interaction of the IL6 haplotype and physical work load was significant for duration of back and leg pain and sick leaves (p=0.010, 0.004 and 0.018, respectively). Discussion: This is the first observation of any prognostic genotype among sciatica patients. The IL6 haplotype GGGA predicted the number of days with back or leg pain, and sickness absence. Subjects with the IL6 haplotype may be more vulnerable when exposed to physically demanding job


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_20 | Pages 73 - 73
1 Nov 2016
Zarrabian M Aleem I Duncan J Ahmed A Eck J Rhee J Currier B Nassr A
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Although patient-reported outcomes (PROs) have become increasingly important in the evaluation of spine surgery patients, interpretability may be limited by a patient's ability to recall pre-intervention impairment. The accuracy of patient recall of preoperative back pain, leg pain, and disability after spine surgery remains unknown. We sought to characterise the accuracy of patient recall of preoperative symptoms in a cohort of lumbar spine surgery patients. We analysed consecutive patients undergoing lumbar decompression or decompression and fusion for lumbar radiculopathy by a single surgeon over a four-year period. Using standardised questionnaires, we recorded back and leg numeric pain scores (NPS) and Oswestry Disability Indices (ODI) preoperatively and asked patients to recall their preoperative status at a minimum of one-year following surgery. We then statistically compared and characterised patient recall of their pre-operative status and their actual pre-operative status. Patients with incomplete follow up or diagnoses other than degenerative lumbar stenosis were excluded. Sixty-seven patients with a mean age of 66.1 years (55% female) were included in the final analysis. All cases were either posterior or combined anterior/ posterior procedures. Mean levels of surgery was 1.7 and 93.8% of all cases were instrumented. Mean duration of preoperative symptoms was 44.5 months (3.7 years). Preoperative vs postoperative PROs improved with regards to NPS back (5.2 vs 2.2, p= to 2 point difference), exceeding the minimal clinical important difference (MCID) for NPS. This pattern was maintained across age, gender, and duration of preoperative symptoms. We also observed cases of symptom minimisation recall bias, and cases in which back and leg pain predominance were switched in severity during recall bias. Significant recall bias of preoperative symptoms exists in patients undergoing spine surgery, potentially limiting accurate assessment and interpretation of PROs. An understanding of PROs and their limitations is essential to assess treatment efficacy of spinal procedures


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_1 | Pages 9 - 9
1 Jan 2022
Haleem S Ahmed A Ganesan S McGillion S Fowler J
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Abstract. Objective. Flexible stabilisation has been utilised to maintain spinal mobility in patients with early-stage lumbar spinal stenosis (LSS). Previous literature has not yet established any non-fusion solution as a viable treatment option for patients with severe posterior degeneration of the lumbar spine. This feasibility study evaluates the mean five-year outcomes of patients treated with the TOPS (Total Posterior Spine System) facet replacement system in the surgical management of lumbar spinal stenosis and degenerative spondylolisthesis. Methods. Ten patients (2 males, 8 females, mean age 59.6) were enrolled into a non-randomised prospective clinical study. Patients were evaluated with standing AP, lateral, flexion and extension radiographs and MRI scans, back and leg pain visual analog scale (VAS) scores, Oswestry Disability Index (ODI), Zurich Claudication Questionnaire (ZCQ) and the SF-36 questionnaires, preoperatively, 6 months, one year, two years and latest follow-up at a mean of five years postoperatively (range 55–74 months). Flexion and extension standing lumbar spine radiographs were obtained at 2 years to assess range of motion (ROM) at the stabilised segment. Results. The clinical outcome scores for the cohort improved significantly across all scoring systems. Radiographs at 2 years did not reveal any loss of position or loosening of metal work. There were two incidental durotomies and no failures at 5 years with no patient requiring revision surgery. Conclusions. The TOPS implant maintains clinical improvement and motion in the surgical management of LSS and spondylolisthesis, indicating it can be considered an option for these indications


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 233 - 233
1 Mar 2010
Prout M Thacker M Barnard K Beith I
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Purpose of study: Pain mechanisms underlying the majority of low back and leg pain remain to be elucidated. A recently developed neuropathic pain questionnaire (PainDETECT) was used to assess for the presence of probable neuropathic pain in a group of patients with low back ± leg pain and the effect this has on them. Method: Patients with low back ± leg pain referred to an Extended Scope Practitioner Physiotherapy clinic who consented to take part completed the PainDETECT questionnaire, and the Roland Morris Disability Questionnaire, and the Fear Avoidance Beliefs Questionnaire. Patients were then grouped by the PainDETECT score into probable neuropathic pain, unlikely neuropathic pain or pain of uncertain underlying mechanism. In patients imaged subsequent to assessment in the clinic (MRI) the PainDETECT scores were compared to evidence of compression of nerve roots. Results: 17% of patients had probable neuropathic pain, in 47% neuropathic pain unlikely and 36% uncertain. Those with probable neuropathic pain when compared to unlikely neuropathic pain were more disabled (p> .001), scored higher on a visual analogue scale (p=0.013), but were no different on the Fear avoidance scale (p=0.08). Those with neuropathic components to their pain always reported leg pain (93% below knee), whereas 63% of unlikely neuropathic pain patients had leg pain (38% below knee). The relationship between nerve root compression and neuropathic pain score was uncertain. Conclusion: Patients with a neuropathic component to their back pain report higher levels of pain, more leg pain and are more disabled by their problem